| Year |
Citation |
Score |
| 2016 |
Haley J, Tomar S, Pulliam N, Xiong S, Perkins SM, Karpf AR, Mitra S, Nephew KP, Mitra AK. Functional characterization of a panel of high-grade serous ovarian cancer cell lines as representative experimental models of the disease. Oncotarget. PMID 27147568 DOI: 10.18632/oncotarget.9053 |
1 |
|
| 2016 |
Özeş AR, Miller DF, Özeş ON, Fang F, Liu Y, Matei D, Huang T, Nephew KP. NF-κB-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer. Oncogene. PMID 27041570 DOI: 10.1038/onc.2016.75 |
1 |
|
| 2015 |
Cooley M, Fang P, Fang F, P Nephew K, Chien J. Molecular determinants of chemotherapy resistance in ovarian cancer. Pharmacogenomics. PMID 26554863 DOI: 10.2217/pgs.15.130 |
1 |
|
| 2015 |
Bowtell DD, Böhm S, Ahmed AA, Aspuria PJ, Bast RC, Beral V, Berek JS, Birrer MJ, Blagden S, Bookman MA, Brenton JD, Chiappinelli KB, Martins FC, Coukos G, Drapkin R, ... ... Nephew KP, et al. Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer. Nature Reviews. Cancer. 15: 668-79. PMID 26493647 DOI: 10.1038/nrc4019 |
1 |
|
| 2015 |
Benson EA, Skaar TC, Liu Y, Nephew KP, Matei D. Carboplatin with Decitabine Therapy, in Recurrent Platinum Resistant Ovarian Cancer, Alters Circulating miRNAs Concentrations: A Pilot Study. Plos One. 10: e0141279. PMID 26485143 DOI: 10.1371/journal.pone.0141279 |
1 |
|
| 2015 |
Rhodes LV, Tate CR, Hoang VT, Burks HE, Gilliam D, Martin EC, Elliott S, Miller DB, Buechlein A, Rusch D, Tang H, Nephew KP, Burow ME, Collins-Burow BM. Regulation of triple-negative breast cancer cell metastasis by the tumor-suppressor liver kinase B1. Oncogenesis. 4: e168. PMID 26436950 DOI: 10.1038/oncsis.2015.27 |
1 |
|
| 2015 |
Rhodes LV, Martin EC, Segar HC, Miller DF, Buechlein A, Rusch DB, Nephew KP, Burow ME, Collins-Burow BM. Dual regulation by microRNA-200b-3p and microRNA-200b-5p in the inhibition of epithelial-to-mesenchymal transition in triple-negative breast cancer. Oncotarget. 6: 16638-52. PMID 26062653 |
1 |
|
| 2015 |
Mitra AK, Davis DA, Tomar S, Roy L, Gurler H, Xie J, Lantvit DD, Cardenas H, Fang F, Liu Y, Loughran E, Yang J, Sharon Stack M, Emerson RE, Cowden Dahl KD, ... ... Nephew KP, et al. In vivo tumor growth of high-grade serous ovarian cancer cell lines. Gynecologic Oncology. PMID 26050922 DOI: 10.1016/j.ygyno.2015.05.040 |
1 |
|
| 2015 |
Chou JL, Huang RL, Shay J, Chen LY, Lin SJ, Yan PS, Chao WT, Lai YH, Lai YL, Chao TK, Lee CI, Tai CK, Wu SF, Nephew KP, Huang TH, et al. Hypermethylation of the TGF-β target, ABCA1 is associated with poor prognosis in ovarian cancer patients. Clinical Epigenetics. 7: 1. PMID 25628764 DOI: 10.1186/s13148-014-0036-2 |
1 |
|
| 2015 |
Miller DF, Yan PX, Fang F, Buechlein A, Ford JB, Tang H, Huang TH, Burow ME, Liu Y, Rusch DB, Nephew KP. Stranded Whole Transcriptome RNA-Seq for All RNA Types. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. 84: 11.14.1-11.14.23. PMID 25599667 DOI: 10.1002/0471142905.hg1114s84 |
1 |
|
| 2015 |
Chen Z, Lan X, Thomas-Ahner JM, Wu D, Liu X, Ye Z, Wang L, Sunkel B, Grenade C, Chen J, Zynger DL, Yan PS, Huang J, Nephew KP, Huang TH, et al. Agonist and antagonist switch DNA motifs recognized by human androgen receptor in prostate cancer. The Embo Journal. 34: 502-16. PMID 25535248 DOI: 10.15252/embj.201490306 |
1 |
|
| 2015 |
Tang J, Fang F, Miller DF, Pilrose JM, Matei D, Huang TH, Nephew KP. Global DNA methylation profiling technologies and the ovarian cancer methylome. Methods in Molecular Biology (Clifton, N.J.). 1238: 653-75. PMID 25421685 DOI: 10.1007/978-1-4939-1804-1_34 |
1 |
|
| 2015 |
Chae H, Rhee S, Nephew KP, Kim S. BioVLAB-MMIA-NGS: microRNA-mRNA integrated analysis using high-throughput sequencing data. Bioinformatics (Oxford, England). 31: 265-7. PMID 25270639 DOI: 10.1093/bioinformatics/btu614 |
1 |
|
| 2015 |
Strong AL, Shi Z, Strong MJ, Miller DF, Rusch DB, Buechlein AM, Flemington EK, McLachlan JA, Nephew KP, Burow ME, Bunnell BA. Effects of the endocrine-disrupting chemical DDT on self-renewal and differentiation of human mesenchymal stem cells. Environmental Health Perspectives. 123: 42-8. PMID 25014179 DOI: 10.1289/ehp.1408188 |
1 |
|
| 2014 |
Cardenas H, Vieth E, Lee J, Segar M, Liu Y, Nephew KP, Matei D. TGF-β induces global changes in DNA methylation during the epithelial-to-mesenchymal transition in ovarian cancer cells. Epigenetics : Official Journal of the Dna Methylation Society. 9: 1461-72. PMID 25470663 DOI: 10.4161/15592294.2014.971608 |
1 |
|
| 2014 |
Mourad R, Hsu PY, Juan L, Shen C, Koneru P, Lin H, Liu Y, Nephew K, Huang TH, Li L. Estrogen induces global reorganization of chromatin structure in human breast cancer cells. Plos One. 9: e113354. PMID 25470140 DOI: 10.1371/journal.pone.0113354 |
1 |
|
| 2014 |
Zhuang Y, Nguyen HT, Burow ME, Zhuo Y, El-Dahr SS, Yao X, Cao S, Flemington EK, Nephew KP, Fang F, Collins-Burow B, Rhodes LV, Yu Q, Jayawickramarajah J, Shan B. Elevated expression of long intergenic non-coding RNA HOTAIR in a basal-like variant of MCF-7 breast cancer cells. Molecular Carcinogenesis. PMID 25328122 DOI: 10.1002/mc.22237 |
1 |
|
| 2014 |
Fang F, Munck J, Tang J, Taverna P, Wang Y, Miller DF, Pilrose J, Choy G, Azab M, Pawelczak KS, VanderVere-Carozza P, Wagner M, Lyons J, Matei D, Turchi JJ, ... Nephew KP, et al. The novel, small-molecule DNA methylation inhibitor SGI-110 as an ovarian cancer chemosensitizer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 6504-16. PMID 25316809 DOI: 10.1158/1078-0432.CCR-14-1553 |
1 |
|
| 2014 |
Martin EC, Rhodes LV, Elliott S, Krebs AE, Nephew KP, Flemington EK, Collins-Burow BM, Burow ME. microRNA regulation of mammalian target of rapamycin expression and activity controls estrogen receptor function and RAD001 sensitivity. Molecular Cancer. 13: 229. PMID 25283550 DOI: 10.1186/1476-4598-13-229 |
1 |
|
| 2014 |
Wang Y, Cardenas H, Fang F, Condello S, Taverna P, Segar M, Liu Y, Nephew KP, Matei D. Epigenetic targeting of ovarian cancer stem cells. Cancer Research. 74: 4922-36. PMID 25035395 DOI: 10.1158/0008-5472.CAN-14-1022 |
1 |
|
| 2014 |
Fang F, Zuo Q, Pilrose J, Wang Y, Shen C, Li M, Wulfridge P, Matei D, Nephew KP. Decitabine reactivated pathways in platinum resistant ovarian cancer. Oncotarget. 5: 3579-89. PMID 25003579 |
1 |
|
| 2014 |
Lengyel E, Burdette JE, Kenny HA, Matei D, Pilrose J, Haluska P, Nephew KP, Hales DB, Stack MS. Epithelial ovarian cancer experimental models. Oncogene. 33: 3619-33. PMID 23934194 DOI: 10.1038/onc.2013.321 |
1 |
|
| 2013 |
Rawlinson JW, Vaden K, Hunsaker J, Miller DF, Nephew KP. Adenoviral-delivered HE4-HSV-tk sensitizes ovarian cancer cells to ganciclovir. Gene Therapy & Molecular Biology. 15: 120-130. PMID 26005395 |
1 |
|
| 2013 |
Antoon JW, Martin EC, Lai R, Salvo VA, Tang Y, Nitzchke AM, Elliott S, Nam SY, Xiong W, Rhodes LV, Collins-Burow B, David O, Wang G, Shan B, Beckman BS, ... Nephew KP, et al. MEK5/ERK5 signaling suppresses estrogen receptor expression and promotes hormone-independent tumorigenesis. Plos One. 8: e69291. PMID 23950888 DOI: 10.1371/journal.pone.0069291 |
1 |
|
| 2013 |
Rhee JK, Kim K, Chae H, Evans J, Yan P, Zhang BT, Gray J, Spellman P, Huang TH, Nephew KP, Kim S. Integrated analysis of genome-wide DNA methylation and gene expression profiles in molecular subtypes of breast cancer. Nucleic Acids Research. 41: 8464-74. PMID 23887935 DOI: 10.1093/nar/gkt643 |
1 |
|
| 2013 |
Miller DF, Yan PS, Buechlein A, Rodriguez BA, Yilmaz AS, Goel S, Lin H, Collins-Burow B, Rhodes LV, Braun C, Pradeep S, Rupaimoole R, Dalkilic M, Sood AK, Burow ME, ... ... Nephew KP, et al. A new method for stranded whole transcriptome RNA-seq. Methods (San Diego, Calif.). 63: 126-34. PMID 23557989 DOI: 10.1016/j.ymeth.2013.03.023 |
1 |
|
| 2013 |
Di Leva G, Piovan C, Gasparini P, Ngankeu A, Taccioli C, Briskin D, Cheung DG, Bolon B, Anderlucci L, Alder H, Nuovo G, Li M, Iorio MV, Galasso M, Santhanam R, ... ... Nephew KP, et al. Estrogen mediated-activation of miR-191/425 cluster modulates tumorigenicity of breast cancer cells depending on estrogen receptor status. Plos Genetics. 9: e1003311. PMID 23505378 DOI: 10.1371/journal.pgen.1003311 |
1 |
|
| 2013 |
Antoon JW, Nitzchke AM, Martin EC, Rhodes LV, Nam S, Wadsworth S, Salvo VA, Elliott S, Collins-Burow B, Nephew KP, Burow ME. Inhibition of p38 mitogen-activated protein kinase alters microRNA expression and reverses epithelial-to-mesenchymal transition. International Journal of Oncology. 42: 1139-50. PMID 23403951 DOI: 10.3892/ijo.2013.1814 |
1 |
|
| 2012 |
Zhang P, Mourad R, Xiang Y, Huang K, Huang T, Nephew K, Liu Y, Li L. A dynamic time order network for time-series gene expression data analysis. Bmc Systems Biology. 6: S9. PMID 23281615 DOI: 10.1186/1752-0509-6-S3-S9 |
1 |
|
| 2012 |
Nam S, Long X, Kwon C, Kim S, Nephew KP. An integrative analysis of cellular contexts, miRNAs and mRNAs reveals network clusters associated with antiestrogen-resistant breast cancer cells. Bmc Genomics. 13: 732. PMID 23270413 DOI: 10.1186/1471-2164-13-732 |
1 |
|
| 2012 |
Antoon JW, Lai R, Struckhoff AP, Nitschke AM, Elliott S, Martin EC, Rhodes LV, Yoon NS, Salvo VA, Shan B, Beckman BS, Nephew KP, Burow ME. Altered death receptor signaling promotes epithelial-to-mesenchymal transition and acquired chemoresistance. Scientific Reports. 2: 539. PMID 22844580 DOI: 10.1038/srep00539 |
1 |
|
| 2012 |
Bratton MR, Frigo DE, Segar HC, Nephew KP, McLachlan JA, Wiese TE, Burow ME. The organochlorine o,p'-DDT plays a role in coactivator-mediated MAPK crosstalk in MCF-7 breast cancer cells. Environmental Health Perspectives. 120: 1291-6. PMID 22609851 DOI: 10.1289/ehp.1104296 |
1 |
|
| 2012 |
Matei D, Fang F, Shen C, Schilder J, Arnold A, Zeng Y, Berry WA, Huang T, Nephew KP. Epigenetic resensitization to platinum in ovarian cancer. Cancer Research. 72: 2197-205. PMID 22549947 DOI: 10.1158/0008-5472.CAN-11-3909 |
1 |
|
| 2012 |
Balch C, Naegeli K, Nam S, Ballard B, Hyslop A, Melki C, Reilly E, Hur MW, Nephew KP. A unique histone deacetylase inhibitor alters microRNA expression and signal transduction in chemoresistant ovarian cancer cells. Cancer Biology & Therapy. 13: 681-93. PMID 22549158 DOI: 10.4161/cbt.20086 |
1 |
|
| 2012 |
Tilghman SL, Bratton MR, Segar HC, Martin EC, Rhodes LV, Li M, McLachlan JA, Wiese TE, Nephew KP, Burow ME. Endocrine disruptor regulation of microRNA expression in breast carcinoma cells. Plos One. 7: e32754. PMID 22403704 DOI: 10.1371/journal.pone.0032754 |
1 |
|
| 2012 |
Jeon BN, Kim MK, Choi WI, Koh DI, Hong SY, Kim KS, Kim M, Yun CO, Yoon J, Choi KY, Lee KR, Nephew KP, Hur MW. KR-POK interacts with p53 and represses its ability to activate transcription of p21WAF1/CDKN1A. Cancer Research. 72: 1137-48. PMID 22253232 DOI: 10.1158/0008-5472.CAN-11-2433 |
1 |
|
| 2012 |
Chen B, Chen J, House MG, Cullen KJ, Nephew KP, Guo Z. Role of neurofilament light polypeptide in head and neck cancer chemoresistance. Molecular Cancer Research : McR. 10: 305-15. PMID 22246235 DOI: 10.1158/1541-7786.MCR-11-0300 |
1 |
|
| 2012 |
Garofalo M, Romano G, Di Leva G, Nuovo G, Jeon YJ, Ngankeu A, Sun J, Lovat F, Alder H, Condorelli G, Engelman JA, Ono M, Rho JK, Cascione L, Volinia S, ... Nephew KP, et al. EGFR and MET receptor tyrosine kinase-altered microRNA expression induces tumorigenesis and gefitinib resistance in lung cancers. Nature Medicine. 18: 74-82. PMID 22157681 DOI: 10.1038/nm.2577 |
1 |
|
| 2012 |
Hahn NM, Bonney PL, Dhawan D, Jones DR, Balch C, Guo Z, Hartman-Frey C, Fang F, Parker HG, Kwon EM, Ostrander EA, Nephew KP, Knapp DW. Subcutaneous 5-azacitidine treatment of naturally occurring canine urothelial carcinoma: a novel epigenetic approach to human urothelial carcinoma drug development. The Journal of Urology. 187: 302-9. PMID 22099988 DOI: 10.1016/j.juro.2011.09.010 |
1 |
|
| 2012 |
Rhodes LV, Nitschke AM, Segar HC, Martin EC, Driver JL, Elliott S, Nam SY, Li M, Nephew KP, Burow ME, Collins-Burow BM. The histone deacetylase inhibitor trichostatin A alters microRNA expression profiles in apoptosis-resistant breast cancer cells. Oncology Reports. 27: 10-6. PMID 21971930 DOI: 10.3892/or.2011.1488 |
1 |
|
| 2011 |
Vaughan S, Coward JI, Bast RC, Berchuck A, Berek JS, Brenton JD, Coukos G, Crum CC, Drapkin R, Etemadmoghadam D, Friedlander M, Gabra H, Kaye SB, Lord CJ, Lengyel E, ... ... Nephew KP, et al. Rethinking ovarian cancer: recommendations for improving outcomes. Nature Reviews. Cancer. 11: 719-25. PMID 21941283 DOI: 10.1038/nrc3144 |
1 |
|
| 2011 |
Rhodes LV, Bratton MR, Zhu Y, Tilghman SL, Muir SE, Salvo VA, Tate CR, Elliott S, Nephew KP, Collins-Burow BM, Burow ME. Effects of SDF-1-CXCR4 signaling on microRNA expression and tumorigenesis in estrogen receptor-alpha (ER-α)-positive breast cancer cells. Experimental Cell Research. 317: 2573-81. PMID 21906588 DOI: 10.1016/j.yexcr.2011.08.016 |
1 |
|
| 2011 |
Bareford MD, Hamed HA, Tang Y, Cruickshanks N, Burow ME, Fisher PB, Moran RG, Nephew KP, Grant S, Dent P. Sorafenib enhances pemetrexed cytotoxicity through an autophagy-dependent mechanism in cancer cells. Autophagy. 7: 1261-2. PMID 21814046 DOI: 10.4161/auto.7.10.17029 |
1 |
|
| 2011 |
Chen B, Rao X, House MG, Nephew KP, Cullen KJ, Guo Z. GPx3 promoter hypermethylation is a frequent event in human cancer and is associated with tumorigenesis and chemotherapy response. Cancer Letters. 309: 37-45. PMID 21684681 DOI: 10.1016/j.canlet.2011.05.013 |
1 |
|
| 2011 |
Bareford MD, Park MA, Yacoub A, Hamed HA, Tang Y, Cruickshanks N, Eulitt P, Hubbard N, Tye G, Burow ME, Fisher PB, Moran RG, Nephew KP, Grant S, Dent P. Sorafenib enhances pemetrexed cytotoxicity through an autophagy-dependent mechanism in cancer cells. Cancer Research. 71: 4955-67. PMID 21622715 DOI: 10.1158/0008-5472.CAN-11-0898 |
1 |
|
| 2011 |
Yeh KT, Chen TH, Yang HW, Chou JL, Chen LY, Yeh CM, Chen YH, Lin RI, Su HY, Chen GC, Deatherage DE, Huang YW, Yan PS, Lin HJ, Nephew KP, et al. Aberrant TGFβ/SMAD4 signaling contributes to epigenetic silencing of a putative tumor suppressor, RunX1T1 in ovarian cancer. Epigenetics : Official Journal of the Dna Methylation Society. 6: 727-39. PMID 21540640 DOI: 10.4161/epi.6.6.15856 |
1 |
|
| 2011 |
Rhodes LV, Short SP, Neel NF, Salvo VA, Zhu Y, Elliott S, Wei Y, Yu D, Sun M, Muir SE, Fonseca JP, Bratton MR, Segar C, Tilghman SL, Sobolik-Delmaire T, ... ... Nephew KP, et al. Cytokine receptor CXCR4 mediates estrogen-independent tumorigenesis, metastasis, and resistance to endocrine therapy in human breast cancer. Cancer Research. 71: 603-13. PMID 21123450 DOI: 10.1158/0008-5472.CAN-10-3185 |
1 |
|
| 2011 |
Rao X, Di Leva G, Li M, Fang F, Devlin C, Hartman-Frey C, Burow ME, Ivan M, Croce CM, Nephew KP. MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways. Oncogene. 30: 1082-97. PMID 21057537 DOI: 10.1038/onc.2010.487 |
0.4 |
|
| 2010 |
Balch C, Matei DE, Huang TH, Nephew KP. Role of epigenomics in ovarian and endometrial cancers. Epigenomics. 2: 419-47. PMID 22121902 DOI: 10.2217/epi.10.19 |
1 |
|
| 2010 |
Mitchell C, Yacoub A, Hossein H, Martin AP, Bareford MD, Eulitt P, Yang C, Nephew KP, Dent P. Inhibition of MCL-1 in breast cancer cells promotes cell death in vitro and in vivo. Cancer Biology & Therapy. 10: 903-17. PMID 20855960 DOI: 10.4161/cbt.10.9.13273 |
1 |
|
| 2010 |
Foley J, Nickerson NK, Nam S, Allen KT, Gilmore JL, Nephew KP, Riese DJ. EGFR signaling in breast cancer: bad to the bone. Seminars in Cell & Developmental Biology. 21: 951-60. PMID 20813200 DOI: 10.1016/j.semcdb.2010.08.009 |
1 |
|
| 2010 |
Bapat SA, Jin V, Berry N, Balch C, Sharma N, Kurrey N, Zhang S, Fang F, Lan X, Li M, Kennedy B, Bigsby RM, Huang TH, Nephew KP. Multivalent epigenetic marks confer microenvironment-responsive epigenetic plasticity to ovarian cancer cells. Epigenetics. 5: 716-29. PMID 20676026 |
0.64 |
|
| 2010 |
Fang F, Balch C, Schilder J, Breen T, Zhang S, Shen C, Li L, Kulesavage C, Snyder AJ, Nephew KP, Matei DE. A phase 1 and pharmacodynamic study of decitabine in combination with carboplatin in patients with recurrent, platinum-resistant, epithelial ovarian cancer. Cancer. 116: 4043-53. PMID 20564122 DOI: 10.1002/cncr.25204 |
1 |
|
| 2010 |
Hsu PY, Hsu HK, Singer GA, Yan PS, Rodriguez BA, Liu JC, Weng YI, Deatherage DE, Chen Z, Pereira JS, Lopez R, Russo J, Wang Q, Lamartiniere CA, Nephew KP, et al. Estrogen-mediated epigenetic repression of large chromosomal regions through DNA looping. Genome Research. 20: 733-44. PMID 20442245 DOI: 10.1101/gr.101923.109 |
1 |
|
| 2010 |
Rickert EL, Oriana S, Hartman-Frey C, Long X, Webb TT, Nephew KP, Weatherman RV. Synthesis and characterization of fluorescent 4-hydroxytamoxifen conjugates with unique antiestrogenic properties. Bioconjugate Chemistry. 21: 903-10. PMID 20420372 DOI: 10.1021/bc900461h |
1 |
|
| 2010 |
Chou JL, Su HY, Chen LY, Liao YP, Hartman-Frey C, Lai YH, Yang HW, Deatherage DE, Kuo CT, Huang YW, Yan PS, Hsiao SH, Tai CK, Lin HJ, Davuluri RV, ... ... Nephew KP, et al. Promoter hypermethylation of FBXO32, a novel TGF-beta/SMAD4 target gene and tumor suppressor, is associated with poor prognosis in human ovarian cancer. Laboratory Investigation; a Journal of Technical Methods and Pathology. 90: 414-25. PMID 20065949 DOI: 10.1038/labinvest.2009.138 |
1 |
|
| 2010 |
Long X, Fan M, Nephew KP. Estrogen receptor-alpha-interacting cytokeratins potentiate the antiestrogenic activity of fulvestrant. Cancer Biology & Therapy. 9: 389-96. PMID 20061804 |
1 |
|
| 2010 |
Matei DE, Nephew KP. Epigenetic therapies for chemoresensitization of epithelial ovarian cancer. Gynecologic Oncology. 116: 195-201. PMID 19854495 DOI: 10.1016/j.ygyno.2009.09.043 |
1 |
|
| 2009 |
Huang YW, Jansen RA, Fabbri E, Potter D, Liyanarachchi S, Chan MW, Liu JC, Crijns AP, Brown R, Nephew KP, van der Zee AG, Cohn DE, Yan PS, Huang TH, Lin HJ. Identification of candidate epigenetic biomarkers for ovarian cancer detection. Oncology Reports. 22: 853-61. PMID 19724865 DOI: 10.3892/or_00000509 |
1 |
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| 2009 |
Qin H, Chan MW, Liyanarachchi S, Balch C, Potter D, Souriraj IJ, Cheng AS, Agosto-Perez FJ, Nikonova EV, Yan PS, Lin HJ, Nephew KP, Saltz JH, Showe LC, Huang TH, et al. An integrative ChIP-chip and gene expression profiling to model SMAD regulatory modules. Bmc Systems Biology. 3: 73. PMID 19615063 DOI: 10.1186/1752-0509-3-73 |
1 |
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| 2009 |
Balch C, Fang F, Matei DE, Huang TH, Nephew KP. Minireview: epigenetic changes in ovarian cancer. Endocrinology. 150: 4003-11. PMID 19574400 DOI: 10.1210/en.2009-0404 |
1 |
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| 2009 |
Xin F, Li M, Balch C, Thomson M, Fan M, Liu Y, Hammond SM, Kim S, Nephew KP. Computational analysis of microRNA profiles and their target genes suggests significant involvement in breast cancer antiestrogen resistance. Bioinformatics (Oxford, England). 25: 430-4. PMID 19091772 DOI: 10.1093/bioinformatics/btn646 |
1 |
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| 2009 |
Nephew KP, Balch C, Skalnik DG. Methyl group acceptance assay for the determination of global DNA methylation levels. Methods in Molecular Biology (Clifton, N.J.). 507: 35-41. PMID 18987804 DOI: 10.1007/978-1-59745-522-0_3 |
1 |
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| 2008 |
Chan MW, Huang YW, Hartman-Frey C, Kuo CT, Deatherage D, Qin H, Cheng AS, Yan PS, Davuluri RV, Huang TH, Nephew KP, Lin HJ. Aberrant transforming growth factor beta1 signaling and SMAD4 nuclear translocation confer epigenetic repression of ADAM19 in ovarian cancer. Neoplasia (New York, N.Y.). 10: 908-19. PMID 18714391 |
0.4 |
|
| 2008 |
Long X, Fan M, Bigsby RM, Nephew KP. Apigenin inhibits antiestrogen-resistant breast cancer cell growth through estrogen receptor-alpha-dependent and estrogen receptor-alpha-independent mechanisms. Molecular Cancer Therapeutics. 7: 2096-108. PMID 18645020 DOI: 10.1158/1535-7163.MCT-07-2350 |
1 |
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| 2008 |
Zhang S, Balch C, Chan MW, Lai HC, Matei D, Schilder JM, Yan PS, Huang TH, Nephew KP. Identification and characterization of ovarian cancer-initiating cells from primary human tumors. Cancer Research. 68: 4311-20. PMID 18519691 DOI: 10.1158/0008-5472.CAN-08-0364 |
1 |
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| 2008 |
Tan B, Long X, Nakshatri H, Nephew KP, Bigsby RM. Striatin-3 gamma inhibits estrogen receptor activity by recruiting a protein phosphatase. Journal of Molecular Endocrinology. 40: 199-210. PMID 18434427 DOI: 10.1677/JME-07-0132 |
1 |
|
| 2008 |
Berry NB, Fan M, Nephew KP. Estrogen receptor-alpha hinge-region lysines 302 and 303 regulate receptor degradation by the proteasome. Molecular Endocrinology (Baltimore, Md.). 22: 1535-51. PMID 18388150 DOI: 10.1210/me.2007-0449 |
0.48 |
|
| 2008 |
Wang G, Wang X, Wang Y, Yang JY, Li L, Nephew KP, Edenberg HJ, Zhou FC, Liu Y. Identification of transcription factor and microRNA binding sites in responsible to fetal alcohol syndrome. Bmc Genomics. 9: S19. PMID 18366608 DOI: 10.1186/1471-2164-9-S1-S19 |
1 |
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| 2008 |
Cheng AS, Culhane AC, Chan MW, Venkataramu CR, Ehrich M, Nasir A, Rodriguez BA, Liu J, Yan PS, Quackenbush J, Nephew KP, Yeatman TJ, Huang TH. Epithelial progeny of estrogen-exposed breast progenitor cells display a cancer-like methylome. Cancer Research. 68: 1786-96. PMID 18339859 DOI: 10.1158/0008-5472.CAN-07-5547 |
1 |
|
| 2008 |
Bapat S, Collins A, Dean M, Nephew K, Rasheed S. Cancer Stem Cells: Similarities and Variations in the Theme of Normal Stem Cells Cancer Stem Cells: Identification and Targets. 1-26. DOI: 10.1002/9780470391594.ch1 |
1 |
|
| 2007 |
Abbosh PH, Li X, Li L, Gardner TA, Kao C, Nephew KP. A conditionally replicative, Wnt/beta-catenin pathway-based adenovirus therapy for anaplastic thyroid cancer. Cancer Gene Therapy. 14: 399-408. PMID 17218945 DOI: 10.1038/sj.cgt.7701024 |
1 |
|
| 2007 |
Fan M, Rickert EL, Chen L, Aftab SA, Nephew KP, Weatherman RV. Characterization of molecular and structural determinants of selective estrogen receptor downregulators. Breast Cancer Research and Treatment. 103: 37-44. PMID 17033922 DOI: 10.1007/s10549-006-9353-2 |
1 |
|
| 2006 |
Fan M, Yan PS, Hartman-Frey C, Chen L, Paik H, Oyer SL, Salisbury JD, Cheng AS, Li L, Abbosh PH, Huang TH, Nephew KP. Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant. Cancer Research. 66: 11954-66. PMID 17178894 DOI: 10.1158/0008-5472.CAN-06-1666 |
1 |
|
| 2006 |
Li L, Cheng AS, Jin VX, Paik HH, Fan M, Li X, Zhang W, Robarge J, Balch C, Davuluri RV, Kim S, Huang TH, Nephew KP. A mixture model-based discriminate analysis for identifying ordered transcription factor binding site pairs in gene promoters directly regulated by estrogen receptor-alpha. Bioinformatics (Oxford, England). 22: 2210-6. PMID 16809387 DOI: 10.1093/bioinformatics/btl329 |
0.48 |
|
| 2006 |
Abbosh PH, Montgomery JS, Starkey JA, Novotny M, Zuhowski EG, Egorin MJ, Moseman AP, Golas A, Brannon KM, Balch C, Huang TH, Nephew KP. Dominant-negative histone H3 lysine 27 mutant derepresses silenced tumor suppressor genes and reverses the drug-resistant phenotype in cancer cells. Cancer Research. 66: 5582-91. PMID 16740693 DOI: 10.1158/0008-5472.CAN-05-3575 |
1 |
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| 2006 |
Wei SH, Balch C, Paik HH, Kim YS, Baldwin RL, Liyanarachchi S, Li L, Wang Z, Wan JC, Davuluri RV, Karlan BY, Gifford G, Brown R, Kim S, Huang TH, ... Nephew KP, et al. Prognostic DNA methylation biomarkers in ovarian cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 2788-94. PMID 16675572 DOI: 10.1158/1078-0432.CCR-05-1551 |
1 |
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| 2006 |
Long X, Nephew KP. Fulvestrant (ICI 182,780)-dependent interacting proteins mediate immobilization and degradation of estrogen receptor-alpha. The Journal of Biological Chemistry. 281: 9607-15. PMID 16459337 DOI: 10.1074/jbc.M510809200 |
1 |
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| 2006 |
Cheng AS, Jin VX, Fan M, Smith LT, Liyanarachchi S, Yan PS, Leu YW, Chan MW, Plass C, Nephew KP, Davuluri RV, Huang TH. Combinatorial analysis of transcription factor partners reveals recruitment of c-MYC to estrogen receptor-alpha responsive promoters. Molecular Cell. 21: 393-404. PMID 16455494 DOI: 10.1016/j.molcel.2005.12.016 |
1 |
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| 2005 |
Balch C, Yan P, Craft T, Young S, Skalnik DG, Huang TH, Nephew KP. Antimitogenic and chemosensitizing effects of the methylation inhibitor zebularine in ovarian cancer. Molecular Cancer Therapeutics. 4: 1505-14. PMID 16227399 DOI: 10.1158/1535-7163.MCT-05-0216 |
1 |
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| 2005 |
Fan M, Park A, Nephew KP. CHIP (carboxyl terminus of Hsc70-interacting protein) promotes basal and geldanamycin-induced degradation of estrogen receptor-alpha. Molecular Endocrinology (Baltimore, Md.). 19: 2901-14. PMID 16037132 DOI: 10.1210/me.2005-0111 |
0.48 |
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| 2005 |
Abbosh PH, Nephew KP. Multiple signaling pathways converge on beta-catenin in thyroid cancer. Thyroid : Official Journal of the American Thyroid Association. 15: 551-61. PMID 16029121 DOI: 10.1089/thy.2005.15.551 |
1 |
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| 2005 |
Li L, Shi H, Yiannoutsos C, Huang TH, Nephew KP. Epigenetic hypothesis tests for methylation and acetylation in a triple microarray system. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 12: 370-90. PMID 15857248 DOI: 10.1089/cmb.2005.12.370 |
1 |
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| 2005 |
Reed CA, Berndtson AK, Nephew KP. Dose-dependent effects of 4-hydroxytamoxifen, the active metabolite of tamoxifen, on estrogen receptor-α expression in the rat uterus Anti-Cancer Drugs. 16: 559-567. PMID 15846122 DOI: 10.1097/00001813-200506000-00012 |
1 |
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| 2004 |
Jin VX, Leu YW, Liyanarachchi S, Sun H, Fan M, Nephew KP, Huang TH, Davuluri RV. Identifying estrogen receptor alpha target genes using integrated computational genomics and chromatin immunoprecipitation microarray. Nucleic Acids Research. 32: 6627-35. PMID 15608294 DOI: 10.1093/nar/gkh1005 |
0.48 |
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| 2004 |
Leu YW, Yan PS, Fan M, Jin VX, Liu JC, Curran EM, Welshons WV, Wei SH, Davuluri RV, Plass C, Nephew KP, Huang TH. Loss of estrogen receptor signaling triggers epigenetic silencing of downstream targets in breast cancer. Cancer Research. 64: 8184-92. PMID 15548683 DOI: 10.1158/0008-5472.CAN-04-2045 |
1 |
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| 2004 |
Fan M, Nakshatri H, Nephew KP. Inhibiting proteasomal proteolysis sustains estrogen receptor-alpha activation. Molecular Endocrinology (Baltimore, Md.). 18: 2603-15. PMID 15284335 DOI: 10.1210/me.2004-0164 |
0.48 |
|
| 2004 |
Berry NB, Cho YM, Harrington MA, Williams SD, Foley J, Nephew KP. Transcriptional targeting in ovarian cancer cells using the human epididymis protein 4 promoter. Gynecologic Oncology. 92: 896-904. PMID 14984958 DOI: 10.1016/j.ygyno.2003.12.024 |
1 |
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| 2004 |
Bigsby RM, Caperell-Grant A, Berry N, Nephew K, Lubahn D. Estrogen induces a systemic growth factor through an estrogen receptor-alpha-dependent mechanism. Biology of Reproduction. 70: 178-83. PMID 13679309 DOI: 10.1095/biolreprod.103.021337 |
0.64 |
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| 2003 |
Fan M, Bigsby RM, Nephew KP. The NEDD8 pathway is required for proteasome-mediated degradation of human estrogen receptor (ER)-alpha and essential for the antiproliferative activity of ICI 182,780 in ERalpha-positive breast cancer cells. Molecular Endocrinology (Baltimore, Md.). 17: 356-65. PMID 12554766 DOI: 10.1210/me.2002-0323 |
0.64 |
|
| 2002 |
Bailey JA, Nephew KP. Strain differences in tamoxifen sensitivity of Sprague-Dawley and Fischer 344 rats Anti-Cancer Drugs. 13: 939-948. PMID 12394257 DOI: 10.1097/00001813-200210000-00006 |
1 |
|
| 2002 |
Fan M, Long X, Bailey JA, Reed CA, Osborne E, Gize EA, Kirk EA, Bigsby RM, Nephew KP. The activating enzyme of NEDD8 inhibits steroid receptor function. Molecular Endocrinology (Baltimore, Md.). 16: 315-30. PMID 11818503 DOI: 10.1210/mend.16.2.0778 |
1 |
|
| 2001 |
Long X, Gize EA, Nephew K, Bigsby RM. Evidence for estrogenic contamination of the MAPK inhibitor PD98059. Endocrinology. 142: 5390-3. PMID 11713241 DOI: 10.1210/endo.142.12.8649 |
0.52 |
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| 2001 |
Ahluwalia A, Hurteau JA, Bigsby RM, Nephew KP. DNA methylation in ovarian cancer. II. Expression of DNA methyltransferases in ovarian cancer cell lines and normal ovarian epithelial cells. Gynecologic Oncology. 82: 299-304. PMID 11531283 DOI: 10.1006/gyno.2001.6284 |
1 |
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| 2001 |
Ahluwalia A, Yan P, Hurteau JA, Bigsby RM, Jung SH, Huang TH, Nephew KP. DNA methylation and ovarian cancer. I. Analysis of CpG island hypermethylation in human ovarian cancer using differential methylation hybridization. Gynecologic Oncology. 82: 261-8. PMID 11531277 DOI: 10.1006/gyno.2001.6291 |
0.64 |
|
| 2001 |
Cárdenas H, Burke KA, Bigsby RM, Pope WF, Nephew KP. Estrogen receptor beta in the sheep ovary during the estrous cycle and early pregnancy. Biology of Reproduction. 65: 128-34. PMID 11420232 DOI: 10.1095/biolreprod65.1.128 |
1 |
|
| 2001 |
Long X, Burke KA, Bigsby RM, Nephew KP. Effects of the xenoestrogen bisphenol A on expression of vascular endothelial growth factor (VEGF) in the rat. Experimental Biology and Medicine (Maywood, N.J.). 226: 477-83. PMID 11393178 |
1 |
|
| 2001 |
Hlaing M, Nam K, Lou J, Pope WF, Nephew KP. Evidence for expression of estrogen receptor cofactor messenger ribonucleic acid in the ovary and uterus of domesticated animals (sheep, cow and pig). Life Sciences. 68: 1427-38. PMID 11388694 DOI: 10.1016/S0024-3205(01)00937-7 |
0.76 |
|
| 2000 |
Nephew KP, Ray S, Hlaing M, Ahluwalia A, Wu SD, Long X, Hyder SM, Bigsby RM. Expression of estrogen receptor coactivators in the rat uterus. Biology of Reproduction. 63: 361-7. PMID 10906038 |
1 |
|
| 2000 |
Burke KA, Schroeder DM, Abel RA, Richardson SC, Bigsby RM, Nephew KP. Immunohistochemical detection of estrogen receptor alpha in male rat spinal cord during development. Journal of Neuroscience Research. 61: 329-37. PMID 10900080 DOI: 10.1002/1097-4547(20000801)61:3<329::AID-JNR11>3.0.CO;2-A |
1 |
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| 2000 |
Long X, Steinmetz R, Ben-Jonathan N, Caperell-Grant A, Young PC, Nephew KP, Bigsby RM. Strain differences in vaginal responses to the xenoestrogen bisphenol A. Environmental Health Perspectives. 108: 243-7. PMID 10706531 |
1 |
|
| 2000 |
Puga A, Barnes SJ, Chang C, Zhu H, Nephew KP, Khan SA, Shertzer HG. Activation of transcription factors activator protein-1 and nuclear factor-kappaB by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Biochemical Pharmacology. 59: 997-1005. PMID 10692565 DOI: 10.1016/S0006-2952(99)00406-2 |
1 |
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| 2000 |
Nephew KP, Long X, Osborne E, Burke KA, Ahluwalia A, Bigsby RM. Effect of estradiol on estrogen receptor expression in rat uterine cell types. Biology of Reproduction. 62: 168-77. PMID 10611082 |
1 |
|
| 1997 |
Allen DL, Mitchner NA, Uveges TE, Nephew KP, Khan S, Ben-Jonathan N. Cell-specific induction of c-fos expression in the pituitary gland by estrogen. Endocrinology. 138: 2128-35. PMID 9112413 DOI: 10.1210/endo.138.5.5101 |
1 |
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| 1994 |
Nephew KP, Cárdenas H, McClure KE, Ott TL, Bazer FW, Pope WF. Effects of administration of human chorionic gonadotropin or progesterone before maternal recognition of pregnancy on blastocyst development and pregnancy in sheep. Journal of Animal Science. 72: 453-8. PMID 8157530 DOI: 10.2527/1994.722453x |
0.76 |
|
| 1993 |
Nephew KP, Webb DK, Akcali KC, Moulton BC, Khan SA. Hormonal regulation and expression of the jun-D protooncogene in specific cell types of the rat uterus Journal of Steroid Biochemistry and Molecular Biology. 46: 281-287. PMID 9831476 DOI: 10.1016/0960-0760(93)90217-K |
1 |
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| 1993 |
Day ML, Kurz SG, Nephew KP, Wright MD, Hu Y, Ford SP, Pope WF. Influence of catecholestradiol on short-lived corpora lutea in beef cows. Domestic Animal Endocrinology. 10: 95-102. PMID 8391961 DOI: 10.1016/0739-7240(93)90015-4 |
0.76 |
|
| 1992 |
Nephew KP, Xie S, Broermann-Ridder DM, McClure KE, Pope WF. Influence of the embryo on intrauterine migration in sheep. Journal of Animal Science. 70: 1911-5. PMID 1634415 DOI: 10.2527/1992.7061911x |
0.76 |
|
| 1991 |
Nephew KP, McClure KE, Ott TL, Dubois DH, Bazer FW, Pope WF. Relationship between variation in conceptus development and differences in estrous cycle duration in ewes. Biology of Reproduction. 44: 536-9. PMID 2015370 DOI: 10.1095/biolreprod44.3.536 |
0.76 |
|
| 1991 |
Hu Y, Nephew KP, Pope WF, Day ML. Uterine influences on the formation of subnormal corpora lutea in seasonally anestrous ewes. Journal of Animal Science. 69: 2532-7. PMID 1885368 DOI: 10.2527/1991.6962532x |
0.76 |
|
| 1990 |
Broermann DM, Xie S, Nephew KP, Pope WF. Limitations of oviductal transfers in swine. Theriogenology. 33: 709-21. PMID 16726767 DOI: 10.1016/0093-691X(90)90548-8 |
0.76 |
|
| 1990 |
Xie S, Broermann DM, Nephew KP, Bishop MD, Pope WF. Relationship between oocyte maturation and fertilization on zygotic diversity in swine. Journal of Animal Science. 68: 2027-33. PMID 2384393 DOI: 10.2527/1990.6872027x |
0.76 |
|
| 1990 |
Xie S, Broermann DM, Nephew KP, Geisert RD, Pope WF. Ovulation and early embryogenesis in swine. Biology of Reproduction. 43: 236-40. PMID 2378935 DOI: 10.1095/biolreprod43.2.236 |
0.76 |
|
| 1990 |
Xie S, Broermann DM, Nephew KP, Ottobre JS, Day ML, Pope WF. Changes in follicular endocrinology during final maturation of porcine oocytes. Domestic Animal Endocrinology. 7: 75-82. PMID 2311376 DOI: 10.1016/0739-7240(90)90056-6 |
0.76 |
|
| 1990 |
Nephew KP, McClure KE, Day ML, Xie S, Roberts RM, Pope WF. Effects of intramuscular administration of recombinant bovine interferon-alpha I1 during the period of maternal recognition of pregnancy. Journal of Animal Science. 68: 2766-70. PMID 2211405 DOI: 10.2527/1990.6892766x |
0.76 |
|
| 1990 |
Hu Y, Wright MD, Dyer RM, Nephew KP, Bolze RP, Day ML. Effects of cloprostenol sodium and clenbuterol HCl on reproductive performance in postparium anestrous cows Theriogenology. 34: 127-132. DOI: 10.1016/0093-691X(90)90583-F |
1 |
|
| 1989 |
Nephew KP, McClure KE, Pope WF. Embryonic migration relative to maternal recognition of pregnancy in sheep. Journal of Animal Science. 67: 999-1005. PMID 2715124 DOI: 10.2527/jas1989.674999x |
0.76 |
|
| 1989 |
Broermann DM, Xie S, Nephew KP, Pope WF. Effects of the oviduct and wheat germ agglutinin on enzymatic digestion of porcine zona pellucidae. Journal of Animal Science. 67: 1324-9. PMID 2661516 DOI: 10.2527/jas1989.6751324x |
0.76 |
|
| 1989 |
Nephew KP, Ford SP, Day ML, Pope WF. Extension of short cycles in postpartum beef cows by intrauterine treatment with catecholestradiol. Domestic Animal Endocrinology. 6: 363-70. PMID 2620506 DOI: 10.1016/0739-7240(89)90030-1 |
0.76 |
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