Kenneth P. Nephew - Publications

Indiana University, Bloomington, Bloomington, IN, United States 
Cell Biology, Molecular Biology, Biochemistry

119 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Haley J, Tomar S, Pulliam N, Xiong S, Perkins SM, Karpf AR, Mitra S, Nephew KP, Mitra AK. Functional characterization of a panel of high-grade serous ovarian cancer cell lines as representative experimental models of the disease. Oncotarget. PMID 27147568 DOI: 10.18632/oncotarget.9053  1
2016 Özeş AR, Miller DF, Özeş ON, Fang F, Liu Y, Matei D, Huang T, Nephew KP. NF-κB-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer. Oncogene. PMID 27041570 DOI: 10.1038/onc.2016.75  1
2015 Cooley M, Fang P, Fang F, P Nephew K, Chien J. Molecular determinants of chemotherapy resistance in ovarian cancer. Pharmacogenomics. PMID 26554863 DOI: 10.2217/pgs.15.130  1
2015 Bowtell DD, Böhm S, Ahmed AA, Aspuria PJ, Bast RC, Beral V, Berek JS, Birrer MJ, Blagden S, Bookman MA, Brenton JD, Chiappinelli KB, Martins FC, Coukos G, Drapkin R, ... ... Nephew KP, et al. Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer. Nature Reviews. Cancer. 15: 668-79. PMID 26493647 DOI: 10.1038/nrc4019  1
2015 Benson EA, Skaar TC, Liu Y, Nephew KP, Matei D. Carboplatin with Decitabine Therapy, in Recurrent Platinum Resistant Ovarian Cancer, Alters Circulating miRNAs Concentrations: A Pilot Study. Plos One. 10: e0141279. PMID 26485143 DOI: 10.1371/journal.pone.0141279  1
2015 Rhodes LV, Tate CR, Hoang VT, Burks HE, Gilliam D, Martin EC, Elliott S, Miller DB, Buechlein A, Rusch D, Tang H, Nephew KP, Burow ME, Collins-Burow BM. Regulation of triple-negative breast cancer cell metastasis by the tumor-suppressor liver kinase B1. Oncogenesis. 4: e168. PMID 26436950 DOI: 10.1038/oncsis.2015.27  1
2015 Rhodes LV, Martin EC, Segar HC, Miller DF, Buechlein A, Rusch DB, Nephew KP, Burow ME, Collins-Burow BM. Dual regulation by microRNA-200b-3p and microRNA-200b-5p in the inhibition of epithelial-to-mesenchymal transition in triple-negative breast cancer. Oncotarget. 6: 16638-52. PMID 26062653  1
2015 Mitra AK, Davis DA, Tomar S, Roy L, Gurler H, Xie J, Lantvit DD, Cardenas H, Fang F, Liu Y, Loughran E, Yang J, Sharon Stack M, Emerson RE, Cowden Dahl KD, ... ... Nephew KP, et al. In vivo tumor growth of high-grade serous ovarian cancer cell lines. Gynecologic Oncology. PMID 26050922 DOI: 10.1016/j.ygyno.2015.05.040  1
2015 Chou JL, Huang RL, Shay J, Chen LY, Lin SJ, Yan PS, Chao WT, Lai YH, Lai YL, Chao TK, Lee CI, Tai CK, Wu SF, Nephew KP, Huang TH, et al. Hypermethylation of the TGF-β target, ABCA1 is associated with poor prognosis in ovarian cancer patients. Clinical Epigenetics. 7: 1. PMID 25628764 DOI: 10.1186/s13148-014-0036-2  1
2015 Miller DF, Yan PX, Fang F, Buechlein A, Ford JB, Tang H, Huang TH, Burow ME, Liu Y, Rusch DB, Nephew KP. Stranded Whole Transcriptome RNA-Seq for All RNA Types. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. 84: 11.14.1-11.14.23. PMID 25599667 DOI: 10.1002/0471142905.hg1114s84  1
2015 Chen Z, Lan X, Thomas-Ahner JM, Wu D, Liu X, Ye Z, Wang L, Sunkel B, Grenade C, Chen J, Zynger DL, Yan PS, Huang J, Nephew KP, Huang TH, et al. Agonist and antagonist switch DNA motifs recognized by human androgen receptor in prostate cancer. The Embo Journal. 34: 502-16. PMID 25535248 DOI: 10.15252/embj.201490306  1
2015 Tang J, Fang F, Miller DF, Pilrose JM, Matei D, Huang TH, Nephew KP. Global DNA methylation profiling technologies and the ovarian cancer methylome. Methods in Molecular Biology (Clifton, N.J.). 1238: 653-75. PMID 25421685 DOI: 10.1007/978-1-4939-1804-1_34  1
2015 Chae H, Rhee S, Nephew KP, Kim S. BioVLAB-MMIA-NGS: microRNA-mRNA integrated analysis using high-throughput sequencing data. Bioinformatics (Oxford, England). 31: 265-7. PMID 25270639 DOI: 10.1093/bioinformatics/btu614  1
2015 Strong AL, Shi Z, Strong MJ, Miller DF, Rusch DB, Buechlein AM, Flemington EK, McLachlan JA, Nephew KP, Burow ME, Bunnell BA. Effects of the endocrine-disrupting chemical DDT on self-renewal and differentiation of human mesenchymal stem cells. Environmental Health Perspectives. 123: 42-8. PMID 25014179 DOI: 10.1289/ehp.1408188  1
2014 Cardenas H, Vieth E, Lee J, Segar M, Liu Y, Nephew KP, Matei D. TGF-β induces global changes in DNA methylation during the epithelial-to-mesenchymal transition in ovarian cancer cells. Epigenetics : Official Journal of the Dna Methylation Society. 9: 1461-72. PMID 25470663 DOI: 10.4161/15592294.2014.971608  1
2014 Mourad R, Hsu PY, Juan L, Shen C, Koneru P, Lin H, Liu Y, Nephew K, Huang TH, Li L. Estrogen induces global reorganization of chromatin structure in human breast cancer cells. Plos One. 9: e113354. PMID 25470140 DOI: 10.1371/journal.pone.0113354  1
2014 Zhuang Y, Nguyen HT, Burow ME, Zhuo Y, El-Dahr SS, Yao X, Cao S, Flemington EK, Nephew KP, Fang F, Collins-Burow B, Rhodes LV, Yu Q, Jayawickramarajah J, Shan B. Elevated expression of long intergenic non-coding RNA HOTAIR in a basal-like variant of MCF-7 breast cancer cells. Molecular Carcinogenesis. PMID 25328122 DOI: 10.1002/mc.22237  1
2014 Fang F, Munck J, Tang J, Taverna P, Wang Y, Miller DF, Pilrose J, Choy G, Azab M, Pawelczak KS, VanderVere-Carozza P, Wagner M, Lyons J, Matei D, Turchi JJ, ... Nephew KP, et al. The novel, small-molecule DNA methylation inhibitor SGI-110 as an ovarian cancer chemosensitizer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 6504-16. PMID 25316809 DOI: 10.1158/1078-0432.CCR-14-1553  1
2014 Martin EC, Rhodes LV, Elliott S, Krebs AE, Nephew KP, Flemington EK, Collins-Burow BM, Burow ME. microRNA regulation of mammalian target of rapamycin expression and activity controls estrogen receptor function and RAD001 sensitivity. Molecular Cancer. 13: 229. PMID 25283550 DOI: 10.1186/1476-4598-13-229  1
2014 Wang Y, Cardenas H, Fang F, Condello S, Taverna P, Segar M, Liu Y, Nephew KP, Matei D. Epigenetic targeting of ovarian cancer stem cells. Cancer Research. 74: 4922-36. PMID 25035395 DOI: 10.1158/0008-5472.CAN-14-1022  1
2014 Fang F, Zuo Q, Pilrose J, Wang Y, Shen C, Li M, Wulfridge P, Matei D, Nephew KP. Decitabine reactivated pathways in platinum resistant ovarian cancer. Oncotarget. 5: 3579-89. PMID 25003579  1
2014 Lengyel E, Burdette JE, Kenny HA, Matei D, Pilrose J, Haluska P, Nephew KP, Hales DB, Stack MS. Epithelial ovarian cancer experimental models. Oncogene. 33: 3619-33. PMID 23934194 DOI: 10.1038/onc.2013.321  1
2013 Rawlinson JW, Vaden K, Hunsaker J, Miller DF, Nephew KP. Adenoviral-delivered HE4-HSV-tk sensitizes ovarian cancer cells to ganciclovir. Gene Therapy & Molecular Biology. 15: 120-130. PMID 26005395  1
2013 Antoon JW, Martin EC, Lai R, Salvo VA, Tang Y, Nitzchke AM, Elliott S, Nam SY, Xiong W, Rhodes LV, Collins-Burow B, David O, Wang G, Shan B, Beckman BS, ... Nephew KP, et al. MEK5/ERK5 signaling suppresses estrogen receptor expression and promotes hormone-independent tumorigenesis. Plos One. 8: e69291. PMID 23950888 DOI: 10.1371/journal.pone.0069291  1
2013 Rhee JK, Kim K, Chae H, Evans J, Yan P, Zhang BT, Gray J, Spellman P, Huang TH, Nephew KP, Kim S. Integrated analysis of genome-wide DNA methylation and gene expression profiles in molecular subtypes of breast cancer. Nucleic Acids Research. 41: 8464-74. PMID 23887935 DOI: 10.1093/nar/gkt643  1
2013 Miller DF, Yan PS, Buechlein A, Rodriguez BA, Yilmaz AS, Goel S, Lin H, Collins-Burow B, Rhodes LV, Braun C, Pradeep S, Rupaimoole R, Dalkilic M, Sood AK, Burow ME, ... ... Nephew KP, et al. A new method for stranded whole transcriptome RNA-seq. Methods (San Diego, Calif.). 63: 126-34. PMID 23557989 DOI: 10.1016/j.ymeth.2013.03.023  1
2013 Di Leva G, Piovan C, Gasparini P, Ngankeu A, Taccioli C, Briskin D, Cheung DG, Bolon B, Anderlucci L, Alder H, Nuovo G, Li M, Iorio MV, Galasso M, Santhanam R, ... ... Nephew KP, et al. Estrogen mediated-activation of miR-191/425 cluster modulates tumorigenicity of breast cancer cells depending on estrogen receptor status. Plos Genetics. 9: e1003311. PMID 23505378 DOI: 10.1371/journal.pgen.1003311  1
2013 Antoon JW, Nitzchke AM, Martin EC, Rhodes LV, Nam S, Wadsworth S, Salvo VA, Elliott S, Collins-Burow B, Nephew KP, Burow ME. Inhibition of p38 mitogen-activated protein kinase alters microRNA expression and reverses epithelial-to-mesenchymal transition. International Journal of Oncology. 42: 1139-50. PMID 23403951 DOI: 10.3892/ijo.2013.1814  1
2012 Zhang P, Mourad R, Xiang Y, Huang K, Huang T, Nephew K, Liu Y, Li L. A dynamic time order network for time-series gene expression data analysis. Bmc Systems Biology. 6: S9. PMID 23281615 DOI: 10.1186/1752-0509-6-S3-S9  1
2012 Nam S, Long X, Kwon C, Kim S, Nephew KP. An integrative analysis of cellular contexts, miRNAs and mRNAs reveals network clusters associated with antiestrogen-resistant breast cancer cells. Bmc Genomics. 13: 732. PMID 23270413 DOI: 10.1186/1471-2164-13-732  1
2012 Antoon JW, Lai R, Struckhoff AP, Nitschke AM, Elliott S, Martin EC, Rhodes LV, Yoon NS, Salvo VA, Shan B, Beckman BS, Nephew KP, Burow ME. Altered death receptor signaling promotes epithelial-to-mesenchymal transition and acquired chemoresistance. Scientific Reports. 2: 539. PMID 22844580 DOI: 10.1038/srep00539  1
2012 Bratton MR, Frigo DE, Segar HC, Nephew KP, McLachlan JA, Wiese TE, Burow ME. The organochlorine o,p'-DDT plays a role in coactivator-mediated MAPK crosstalk in MCF-7 breast cancer cells. Environmental Health Perspectives. 120: 1291-6. PMID 22609851 DOI: 10.1289/ehp.1104296  1
2012 Matei D, Fang F, Shen C, Schilder J, Arnold A, Zeng Y, Berry WA, Huang T, Nephew KP. Epigenetic resensitization to platinum in ovarian cancer. Cancer Research. 72: 2197-205. PMID 22549947 DOI: 10.1158/0008-5472.CAN-11-3909  1
2012 Balch C, Naegeli K, Nam S, Ballard B, Hyslop A, Melki C, Reilly E, Hur MW, Nephew KP. A unique histone deacetylase inhibitor alters microRNA expression and signal transduction in chemoresistant ovarian cancer cells. Cancer Biology & Therapy. 13: 681-93. PMID 22549158 DOI: 10.4161/cbt.20086  1
2012 Tilghman SL, Bratton MR, Segar HC, Martin EC, Rhodes LV, Li M, McLachlan JA, Wiese TE, Nephew KP, Burow ME. Endocrine disruptor regulation of microRNA expression in breast carcinoma cells. Plos One. 7: e32754. PMID 22403704 DOI: 10.1371/journal.pone.0032754  1
2012 Jeon BN, Kim MK, Choi WI, Koh DI, Hong SY, Kim KS, Kim M, Yun CO, Yoon J, Choi KY, Lee KR, Nephew KP, Hur MW. KR-POK interacts with p53 and represses its ability to activate transcription of p21WAF1/CDKN1A. Cancer Research. 72: 1137-48. PMID 22253232 DOI: 10.1158/0008-5472.CAN-11-2433  1
2012 Chen B, Chen J, House MG, Cullen KJ, Nephew KP, Guo Z. Role of neurofilament light polypeptide in head and neck cancer chemoresistance. Molecular Cancer Research : McR. 10: 305-15. PMID 22246235 DOI: 10.1158/1541-7786.MCR-11-0300  1
2012 Garofalo M, Romano G, Di Leva G, Nuovo G, Jeon YJ, Ngankeu A, Sun J, Lovat F, Alder H, Condorelli G, Engelman JA, Ono M, Rho JK, Cascione L, Volinia S, ... Nephew KP, et al. EGFR and MET receptor tyrosine kinase-altered microRNA expression induces tumorigenesis and gefitinib resistance in lung cancers. Nature Medicine. 18: 74-82. PMID 22157681 DOI: 10.1038/nm.2577  1
2012 Hahn NM, Bonney PL, Dhawan D, Jones DR, Balch C, Guo Z, Hartman-Frey C, Fang F, Parker HG, Kwon EM, Ostrander EA, Nephew KP, Knapp DW. Subcutaneous 5-azacitidine treatment of naturally occurring canine urothelial carcinoma: a novel epigenetic approach to human urothelial carcinoma drug development. The Journal of Urology. 187: 302-9. PMID 22099988 DOI: 10.1016/j.juro.2011.09.010  1
2012 Rhodes LV, Nitschke AM, Segar HC, Martin EC, Driver JL, Elliott S, Nam SY, Li M, Nephew KP, Burow ME, Collins-Burow BM. The histone deacetylase inhibitor trichostatin A alters microRNA expression profiles in apoptosis-resistant breast cancer cells. Oncology Reports. 27: 10-6. PMID 21971930 DOI: 10.3892/or.2011.1488  1
2011 Vaughan S, Coward JI, Bast RC, Berchuck A, Berek JS, Brenton JD, Coukos G, Crum CC, Drapkin R, Etemadmoghadam D, Friedlander M, Gabra H, Kaye SB, Lord CJ, Lengyel E, ... ... Nephew KP, et al. Rethinking ovarian cancer: recommendations for improving outcomes. Nature Reviews. Cancer. 11: 719-25. PMID 21941283 DOI: 10.1038/nrc3144  1
2011 Rhodes LV, Bratton MR, Zhu Y, Tilghman SL, Muir SE, Salvo VA, Tate CR, Elliott S, Nephew KP, Collins-Burow BM, Burow ME. Effects of SDF-1-CXCR4 signaling on microRNA expression and tumorigenesis in estrogen receptor-alpha (ER-α)-positive breast cancer cells. Experimental Cell Research. 317: 2573-81. PMID 21906588 DOI: 10.1016/j.yexcr.2011.08.016  1
2011 Bareford MD, Hamed HA, Tang Y, Cruickshanks N, Burow ME, Fisher PB, Moran RG, Nephew KP, Grant S, Dent P. Sorafenib enhances pemetrexed cytotoxicity through an autophagy-dependent mechanism in cancer cells. Autophagy. 7: 1261-2. PMID 21814046 DOI: 10.4161/auto.7.10.17029  1
2011 Chen B, Rao X, House MG, Nephew KP, Cullen KJ, Guo Z. GPx3 promoter hypermethylation is a frequent event in human cancer and is associated with tumorigenesis and chemotherapy response. Cancer Letters. 309: 37-45. PMID 21684681 DOI: 10.1016/j.canlet.2011.05.013  1
2011 Bareford MD, Park MA, Yacoub A, Hamed HA, Tang Y, Cruickshanks N, Eulitt P, Hubbard N, Tye G, Burow ME, Fisher PB, Moran RG, Nephew KP, Grant S, Dent P. Sorafenib enhances pemetrexed cytotoxicity through an autophagy-dependent mechanism in cancer cells. Cancer Research. 71: 4955-67. PMID 21622715 DOI: 10.1158/0008-5472.CAN-11-0898  1
2011 Yeh KT, Chen TH, Yang HW, Chou JL, Chen LY, Yeh CM, Chen YH, Lin RI, Su HY, Chen GC, Deatherage DE, Huang YW, Yan PS, Lin HJ, Nephew KP, et al. Aberrant TGFβ/SMAD4 signaling contributes to epigenetic silencing of a putative tumor suppressor, RunX1T1 in ovarian cancer. Epigenetics : Official Journal of the Dna Methylation Society. 6: 727-39. PMID 21540640 DOI: 10.4161/epi.6.6.15856  1
2011 Rhodes LV, Short SP, Neel NF, Salvo VA, Zhu Y, Elliott S, Wei Y, Yu D, Sun M, Muir SE, Fonseca JP, Bratton MR, Segar C, Tilghman SL, Sobolik-Delmaire T, ... ... Nephew KP, et al. Cytokine receptor CXCR4 mediates estrogen-independent tumorigenesis, metastasis, and resistance to endocrine therapy in human breast cancer. Cancer Research. 71: 603-13. PMID 21123450 DOI: 10.1158/0008-5472.CAN-10-3185  1
2011 Rao X, Di Leva G, Li M, Fang F, Devlin C, Hartman-Frey C, Burow ME, Ivan M, Croce CM, Nephew KP. MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways. Oncogene. 30: 1082-97. PMID 21057537 DOI: 10.1038/onc.2010.487  0.4
2010 Balch C, Matei DE, Huang TH, Nephew KP. Role of epigenomics in ovarian and endometrial cancers. Epigenomics. 2: 419-47. PMID 22121902 DOI: 10.2217/epi.10.19  1
2010 Mitchell C, Yacoub A, Hossein H, Martin AP, Bareford MD, Eulitt P, Yang C, Nephew KP, Dent P. Inhibition of MCL-1 in breast cancer cells promotes cell death in vitro and in vivo. Cancer Biology & Therapy. 10: 903-17. PMID 20855960 DOI: 10.4161/cbt.10.9.13273  1
2010 Foley J, Nickerson NK, Nam S, Allen KT, Gilmore JL, Nephew KP, Riese DJ. EGFR signaling in breast cancer: bad to the bone. Seminars in Cell & Developmental Biology. 21: 951-60. PMID 20813200 DOI: 10.1016/j.semcdb.2010.08.009  1
2010 Bapat SA, Jin V, Berry N, Balch C, Sharma N, Kurrey N, Zhang S, Fang F, Lan X, Li M, Kennedy B, Bigsby RM, Huang TH, Nephew KP. Multivalent epigenetic marks confer microenvironment-responsive epigenetic plasticity to ovarian cancer cells. Epigenetics. 5: 716-29. PMID 20676026  0.64
2010 Fang F, Balch C, Schilder J, Breen T, Zhang S, Shen C, Li L, Kulesavage C, Snyder AJ, Nephew KP, Matei DE. A phase 1 and pharmacodynamic study of decitabine in combination with carboplatin in patients with recurrent, platinum-resistant, epithelial ovarian cancer. Cancer. 116: 4043-53. PMID 20564122 DOI: 10.1002/cncr.25204  1
2010 Hsu PY, Hsu HK, Singer GA, Yan PS, Rodriguez BA, Liu JC, Weng YI, Deatherage DE, Chen Z, Pereira JS, Lopez R, Russo J, Wang Q, Lamartiniere CA, Nephew KP, et al. Estrogen-mediated epigenetic repression of large chromosomal regions through DNA looping. Genome Research. 20: 733-44. PMID 20442245 DOI: 10.1101/gr.101923.109  1
2010 Rickert EL, Oriana S, Hartman-Frey C, Long X, Webb TT, Nephew KP, Weatherman RV. Synthesis and characterization of fluorescent 4-hydroxytamoxifen conjugates with unique antiestrogenic properties. Bioconjugate Chemistry. 21: 903-10. PMID 20420372 DOI: 10.1021/bc900461h  1
2010 Chou JL, Su HY, Chen LY, Liao YP, Hartman-Frey C, Lai YH, Yang HW, Deatherage DE, Kuo CT, Huang YW, Yan PS, Hsiao SH, Tai CK, Lin HJ, Davuluri RV, ... ... Nephew KP, et al. Promoter hypermethylation of FBXO32, a novel TGF-beta/SMAD4 target gene and tumor suppressor, is associated with poor prognosis in human ovarian cancer. Laboratory Investigation; a Journal of Technical Methods and Pathology. 90: 414-25. PMID 20065949 DOI: 10.1038/labinvest.2009.138  1
2010 Long X, Fan M, Nephew KP. Estrogen receptor-alpha-interacting cytokeratins potentiate the antiestrogenic activity of fulvestrant. Cancer Biology & Therapy. 9: 389-96. PMID 20061804  1
2010 Matei DE, Nephew KP. Epigenetic therapies for chemoresensitization of epithelial ovarian cancer. Gynecologic Oncology. 116: 195-201. PMID 19854495 DOI: 10.1016/j.ygyno.2009.09.043  1
2009 Huang YW, Jansen RA, Fabbri E, Potter D, Liyanarachchi S, Chan MW, Liu JC, Crijns AP, Brown R, Nephew KP, van der Zee AG, Cohn DE, Yan PS, Huang TH, Lin HJ. Identification of candidate epigenetic biomarkers for ovarian cancer detection. Oncology Reports. 22: 853-61. PMID 19724865 DOI: 10.3892/or_00000509  1
2009 Qin H, Chan MW, Liyanarachchi S, Balch C, Potter D, Souriraj IJ, Cheng AS, Agosto-Perez FJ, Nikonova EV, Yan PS, Lin HJ, Nephew KP, Saltz JH, Showe LC, Huang TH, et al. An integrative ChIP-chip and gene expression profiling to model SMAD regulatory modules. Bmc Systems Biology. 3: 73. PMID 19615063 DOI: 10.1186/1752-0509-3-73  1
2009 Balch C, Fang F, Matei DE, Huang TH, Nephew KP. Minireview: epigenetic changes in ovarian cancer. Endocrinology. 150: 4003-11. PMID 19574400 DOI: 10.1210/en.2009-0404  1
2009 Xin F, Li M, Balch C, Thomson M, Fan M, Liu Y, Hammond SM, Kim S, Nephew KP. Computational analysis of microRNA profiles and their target genes suggests significant involvement in breast cancer antiestrogen resistance. Bioinformatics (Oxford, England). 25: 430-4. PMID 19091772 DOI: 10.1093/bioinformatics/btn646  1
2009 Nephew KP, Balch C, Skalnik DG. Methyl group acceptance assay for the determination of global DNA methylation levels. Methods in Molecular Biology (Clifton, N.J.). 507: 35-41. PMID 18987804 DOI: 10.1007/978-1-59745-522-0_3  1
2008 Chan MW, Huang YW, Hartman-Frey C, Kuo CT, Deatherage D, Qin H, Cheng AS, Yan PS, Davuluri RV, Huang TH, Nephew KP, Lin HJ. Aberrant transforming growth factor beta1 signaling and SMAD4 nuclear translocation confer epigenetic repression of ADAM19 in ovarian cancer. Neoplasia (New York, N.Y.). 10: 908-19. PMID 18714391  0.4
2008 Long X, Fan M, Bigsby RM, Nephew KP. Apigenin inhibits antiestrogen-resistant breast cancer cell growth through estrogen receptor-alpha-dependent and estrogen receptor-alpha-independent mechanisms. Molecular Cancer Therapeutics. 7: 2096-108. PMID 18645020 DOI: 10.1158/1535-7163.MCT-07-2350  1
2008 Zhang S, Balch C, Chan MW, Lai HC, Matei D, Schilder JM, Yan PS, Huang TH, Nephew KP. Identification and characterization of ovarian cancer-initiating cells from primary human tumors. Cancer Research. 68: 4311-20. PMID 18519691 DOI: 10.1158/0008-5472.CAN-08-0364  1
2008 Tan B, Long X, Nakshatri H, Nephew KP, Bigsby RM. Striatin-3 gamma inhibits estrogen receptor activity by recruiting a protein phosphatase. Journal of Molecular Endocrinology. 40: 199-210. PMID 18434427 DOI: 10.1677/JME-07-0132  1
2008 Berry NB, Fan M, Nephew KP. Estrogen receptor-alpha hinge-region lysines 302 and 303 regulate receptor degradation by the proteasome. Molecular Endocrinology (Baltimore, Md.). 22: 1535-51. PMID 18388150 DOI: 10.1210/me.2007-0449  0.48
2008 Wang G, Wang X, Wang Y, Yang JY, Li L, Nephew KP, Edenberg HJ, Zhou FC, Liu Y. Identification of transcription factor and microRNA binding sites in responsible to fetal alcohol syndrome. Bmc Genomics. 9: S19. PMID 18366608 DOI: 10.1186/1471-2164-9-S1-S19  1
2008 Cheng AS, Culhane AC, Chan MW, Venkataramu CR, Ehrich M, Nasir A, Rodriguez BA, Liu J, Yan PS, Quackenbush J, Nephew KP, Yeatman TJ, Huang TH. Epithelial progeny of estrogen-exposed breast progenitor cells display a cancer-like methylome. Cancer Research. 68: 1786-96. PMID 18339859 DOI: 10.1158/0008-5472.CAN-07-5547  1
2008 Bapat S, Collins A, Dean M, Nephew K, Rasheed S. Cancer Stem Cells: Similarities and Variations in the Theme of Normal Stem Cells Cancer Stem Cells: Identification and Targets. 1-26. DOI: 10.1002/9780470391594.ch1  1
2007 Abbosh PH, Li X, Li L, Gardner TA, Kao C, Nephew KP. A conditionally replicative, Wnt/beta-catenin pathway-based adenovirus therapy for anaplastic thyroid cancer. Cancer Gene Therapy. 14: 399-408. PMID 17218945 DOI: 10.1038/sj.cgt.7701024  1
2007 Fan M, Rickert EL, Chen L, Aftab SA, Nephew KP, Weatherman RV. Characterization of molecular and structural determinants of selective estrogen receptor downregulators. Breast Cancer Research and Treatment. 103: 37-44. PMID 17033922 DOI: 10.1007/s10549-006-9353-2  1
2006 Fan M, Yan PS, Hartman-Frey C, Chen L, Paik H, Oyer SL, Salisbury JD, Cheng AS, Li L, Abbosh PH, Huang TH, Nephew KP. Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant. Cancer Research. 66: 11954-66. PMID 17178894 DOI: 10.1158/0008-5472.CAN-06-1666  1
2006 Li L, Cheng AS, Jin VX, Paik HH, Fan M, Li X, Zhang W, Robarge J, Balch C, Davuluri RV, Kim S, Huang TH, Nephew KP. A mixture model-based discriminate analysis for identifying ordered transcription factor binding site pairs in gene promoters directly regulated by estrogen receptor-alpha. Bioinformatics (Oxford, England). 22: 2210-6. PMID 16809387 DOI: 10.1093/bioinformatics/btl329  0.48
2006 Abbosh PH, Montgomery JS, Starkey JA, Novotny M, Zuhowski EG, Egorin MJ, Moseman AP, Golas A, Brannon KM, Balch C, Huang TH, Nephew KP. Dominant-negative histone H3 lysine 27 mutant derepresses silenced tumor suppressor genes and reverses the drug-resistant phenotype in cancer cells. Cancer Research. 66: 5582-91. PMID 16740693 DOI: 10.1158/0008-5472.CAN-05-3575  1
2006 Wei SH, Balch C, Paik HH, Kim YS, Baldwin RL, Liyanarachchi S, Li L, Wang Z, Wan JC, Davuluri RV, Karlan BY, Gifford G, Brown R, Kim S, Huang TH, ... Nephew KP, et al. Prognostic DNA methylation biomarkers in ovarian cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 2788-94. PMID 16675572 DOI: 10.1158/1078-0432.CCR-05-1551  1
2006 Long X, Nephew KP. Fulvestrant (ICI 182,780)-dependent interacting proteins mediate immobilization and degradation of estrogen receptor-alpha. The Journal of Biological Chemistry. 281: 9607-15. PMID 16459337 DOI: 10.1074/jbc.M510809200  1
2006 Cheng AS, Jin VX, Fan M, Smith LT, Liyanarachchi S, Yan PS, Leu YW, Chan MW, Plass C, Nephew KP, Davuluri RV, Huang TH. Combinatorial analysis of transcription factor partners reveals recruitment of c-MYC to estrogen receptor-alpha responsive promoters. Molecular Cell. 21: 393-404. PMID 16455494 DOI: 10.1016/j.molcel.2005.12.016  1
2005 Balch C, Yan P, Craft T, Young S, Skalnik DG, Huang TH, Nephew KP. Antimitogenic and chemosensitizing effects of the methylation inhibitor zebularine in ovarian cancer. Molecular Cancer Therapeutics. 4: 1505-14. PMID 16227399 DOI: 10.1158/1535-7163.MCT-05-0216  1
2005 Fan M, Park A, Nephew KP. CHIP (carboxyl terminus of Hsc70-interacting protein) promotes basal and geldanamycin-induced degradation of estrogen receptor-alpha. Molecular Endocrinology (Baltimore, Md.). 19: 2901-14. PMID 16037132 DOI: 10.1210/me.2005-0111  0.48
2005 Abbosh PH, Nephew KP. Multiple signaling pathways converge on beta-catenin in thyroid cancer. Thyroid : Official Journal of the American Thyroid Association. 15: 551-61. PMID 16029121 DOI: 10.1089/thy.2005.15.551  1
2005 Li L, Shi H, Yiannoutsos C, Huang TH, Nephew KP. Epigenetic hypothesis tests for methylation and acetylation in a triple microarray system. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 12: 370-90. PMID 15857248 DOI: 10.1089/cmb.2005.12.370  1
2005 Reed CA, Berndtson AK, Nephew KP. Dose-dependent effects of 4-hydroxytamoxifen, the active metabolite of tamoxifen, on estrogen receptor-α expression in the rat uterus Anti-Cancer Drugs. 16: 559-567. PMID 15846122 DOI: 10.1097/00001813-200506000-00012  1
2004 Jin VX, Leu YW, Liyanarachchi S, Sun H, Fan M, Nephew KP, Huang TH, Davuluri RV. Identifying estrogen receptor alpha target genes using integrated computational genomics and chromatin immunoprecipitation microarray. Nucleic Acids Research. 32: 6627-35. PMID 15608294 DOI: 10.1093/nar/gkh1005  0.48
2004 Leu YW, Yan PS, Fan M, Jin VX, Liu JC, Curran EM, Welshons WV, Wei SH, Davuluri RV, Plass C, Nephew KP, Huang TH. Loss of estrogen receptor signaling triggers epigenetic silencing of downstream targets in breast cancer. Cancer Research. 64: 8184-92. PMID 15548683 DOI: 10.1158/0008-5472.CAN-04-2045  1
2004 Fan M, Nakshatri H, Nephew KP. Inhibiting proteasomal proteolysis sustains estrogen receptor-alpha activation. Molecular Endocrinology (Baltimore, Md.). 18: 2603-15. PMID 15284335 DOI: 10.1210/me.2004-0164  0.48
2004 Berry NB, Cho YM, Harrington MA, Williams SD, Foley J, Nephew KP. Transcriptional targeting in ovarian cancer cells using the human epididymis protein 4 promoter. Gynecologic Oncology. 92: 896-904. PMID 14984958 DOI: 10.1016/j.ygyno.2003.12.024  1
2004 Bigsby RM, Caperell-Grant A, Berry N, Nephew K, Lubahn D. Estrogen induces a systemic growth factor through an estrogen receptor-alpha-dependent mechanism. Biology of Reproduction. 70: 178-83. PMID 13679309 DOI: 10.1095/biolreprod.103.021337  0.64
2003 Fan M, Bigsby RM, Nephew KP. The NEDD8 pathway is required for proteasome-mediated degradation of human estrogen receptor (ER)-alpha and essential for the antiproliferative activity of ICI 182,780 in ERalpha-positive breast cancer cells. Molecular Endocrinology (Baltimore, Md.). 17: 356-65. PMID 12554766 DOI: 10.1210/me.2002-0323  0.64
2002 Bailey JA, Nephew KP. Strain differences in tamoxifen sensitivity of Sprague-Dawley and Fischer 344 rats Anti-Cancer Drugs. 13: 939-948. PMID 12394257 DOI: 10.1097/00001813-200210000-00006  1
2002 Fan M, Long X, Bailey JA, Reed CA, Osborne E, Gize EA, Kirk EA, Bigsby RM, Nephew KP. The activating enzyme of NEDD8 inhibits steroid receptor function. Molecular Endocrinology (Baltimore, Md.). 16: 315-30. PMID 11818503 DOI: 10.1210/mend.16.2.0778  1
2001 Long X, Gize EA, Nephew K, Bigsby RM. Evidence for estrogenic contamination of the MAPK inhibitor PD98059. Endocrinology. 142: 5390-3. PMID 11713241 DOI: 10.1210/endo.142.12.8649  0.52
2001 Ahluwalia A, Hurteau JA, Bigsby RM, Nephew KP. DNA methylation in ovarian cancer. II. Expression of DNA methyltransferases in ovarian cancer cell lines and normal ovarian epithelial cells. Gynecologic Oncology. 82: 299-304. PMID 11531283 DOI: 10.1006/gyno.2001.6284  1
2001 Ahluwalia A, Yan P, Hurteau JA, Bigsby RM, Jung SH, Huang TH, Nephew KP. DNA methylation and ovarian cancer. I. Analysis of CpG island hypermethylation in human ovarian cancer using differential methylation hybridization. Gynecologic Oncology. 82: 261-8. PMID 11531277 DOI: 10.1006/gyno.2001.6291  0.64
2001 Cárdenas H, Burke KA, Bigsby RM, Pope WF, Nephew KP. Estrogen receptor beta in the sheep ovary during the estrous cycle and early pregnancy. Biology of Reproduction. 65: 128-34. PMID 11420232 DOI: 10.1095/biolreprod65.1.128  1
2001 Long X, Burke KA, Bigsby RM, Nephew KP. Effects of the xenoestrogen bisphenol A on expression of vascular endothelial growth factor (VEGF) in the rat. Experimental Biology and Medicine (Maywood, N.J.). 226: 477-83. PMID 11393178  1
2001 Hlaing M, Nam K, Lou J, Pope WF, Nephew KP. Evidence for expression of estrogen receptor cofactor messenger ribonucleic acid in the ovary and uterus of domesticated animals (sheep, cow and pig). Life Sciences. 68: 1427-38. PMID 11388694 DOI: 10.1016/S0024-3205(01)00937-7  0.76
2000 Nephew KP, Ray S, Hlaing M, Ahluwalia A, Wu SD, Long X, Hyder SM, Bigsby RM. Expression of estrogen receptor coactivators in the rat uterus. Biology of Reproduction. 63: 361-7. PMID 10906038  1
2000 Burke KA, Schroeder DM, Abel RA, Richardson SC, Bigsby RM, Nephew KP. Immunohistochemical detection of estrogen receptor alpha in male rat spinal cord during development. Journal of Neuroscience Research. 61: 329-37. PMID 10900080 DOI: 10.1002/1097-4547(20000801)61:3<329::AID-JNR11>3.0.CO;2-A  1
2000 Long X, Steinmetz R, Ben-Jonathan N, Caperell-Grant A, Young PC, Nephew KP, Bigsby RM. Strain differences in vaginal responses to the xenoestrogen bisphenol A. Environmental Health Perspectives. 108: 243-7. PMID 10706531  1
2000 Puga A, Barnes SJ, Chang C, Zhu H, Nephew KP, Khan SA, Shertzer HG. Activation of transcription factors activator protein-1 and nuclear factor-kappaB by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Biochemical Pharmacology. 59: 997-1005. PMID 10692565 DOI: 10.1016/S0006-2952(99)00406-2  1
2000 Nephew KP, Long X, Osborne E, Burke KA, Ahluwalia A, Bigsby RM. Effect of estradiol on estrogen receptor expression in rat uterine cell types. Biology of Reproduction. 62: 168-77. PMID 10611082  1
1997 Allen DL, Mitchner NA, Uveges TE, Nephew KP, Khan S, Ben-Jonathan N. Cell-specific induction of c-fos expression in the pituitary gland by estrogen. Endocrinology. 138: 2128-35. PMID 9112413 DOI: 10.1210/endo.138.5.5101  1
1994 Nephew KP, Cárdenas H, McClure KE, Ott TL, Bazer FW, Pope WF. Effects of administration of human chorionic gonadotropin or progesterone before maternal recognition of pregnancy on blastocyst development and pregnancy in sheep. Journal of Animal Science. 72: 453-8. PMID 8157530 DOI: 10.2527/1994.722453x  0.76
1993 Nephew KP, Webb DK, Akcali KC, Moulton BC, Khan SA. Hormonal regulation and expression of the jun-D protooncogene in specific cell types of the rat uterus Journal of Steroid Biochemistry and Molecular Biology. 46: 281-287. PMID 9831476 DOI: 10.1016/0960-0760(93)90217-K  1
1993 Day ML, Kurz SG, Nephew KP, Wright MD, Hu Y, Ford SP, Pope WF. Influence of catecholestradiol on short-lived corpora lutea in beef cows. Domestic Animal Endocrinology. 10: 95-102. PMID 8391961 DOI: 10.1016/0739-7240(93)90015-4  0.76
1992 Nephew KP, Xie S, Broermann-Ridder DM, McClure KE, Pope WF. Influence of the embryo on intrauterine migration in sheep. Journal of Animal Science. 70: 1911-5. PMID 1634415 DOI: 10.2527/1992.7061911x  0.76
1991 Nephew KP, McClure KE, Ott TL, Dubois DH, Bazer FW, Pope WF. Relationship between variation in conceptus development and differences in estrous cycle duration in ewes. Biology of Reproduction. 44: 536-9. PMID 2015370 DOI: 10.1095/biolreprod44.3.536  0.76
1991 Hu Y, Nephew KP, Pope WF, Day ML. Uterine influences on the formation of subnormal corpora lutea in seasonally anestrous ewes. Journal of Animal Science. 69: 2532-7. PMID 1885368 DOI: 10.2527/1991.6962532x  0.76
1990 Broermann DM, Xie S, Nephew KP, Pope WF. Limitations of oviductal transfers in swine. Theriogenology. 33: 709-21. PMID 16726767 DOI: 10.1016/0093-691X(90)90548-8  0.76
1990 Xie S, Broermann DM, Nephew KP, Bishop MD, Pope WF. Relationship between oocyte maturation and fertilization on zygotic diversity in swine. Journal of Animal Science. 68: 2027-33. PMID 2384393 DOI: 10.2527/1990.6872027x  0.76
1990 Xie S, Broermann DM, Nephew KP, Geisert RD, Pope WF. Ovulation and early embryogenesis in swine. Biology of Reproduction. 43: 236-40. PMID 2378935 DOI: 10.1095/biolreprod43.2.236  0.76
1990 Xie S, Broermann DM, Nephew KP, Ottobre JS, Day ML, Pope WF. Changes in follicular endocrinology during final maturation of porcine oocytes. Domestic Animal Endocrinology. 7: 75-82. PMID 2311376 DOI: 10.1016/0739-7240(90)90056-6  0.76
1990 Nephew KP, McClure KE, Day ML, Xie S, Roberts RM, Pope WF. Effects of intramuscular administration of recombinant bovine interferon-alpha I1 during the period of maternal recognition of pregnancy. Journal of Animal Science. 68: 2766-70. PMID 2211405 DOI: 10.2527/1990.6892766x  0.76
1990 Hu Y, Wright MD, Dyer RM, Nephew KP, Bolze RP, Day ML. Effects of cloprostenol sodium and clenbuterol HCl on reproductive performance in postparium anestrous cows Theriogenology. 34: 127-132. DOI: 10.1016/0093-691X(90)90583-F  1
1989 Nephew KP, McClure KE, Pope WF. Embryonic migration relative to maternal recognition of pregnancy in sheep. Journal of Animal Science. 67: 999-1005. PMID 2715124 DOI: 10.2527/jas1989.674999x  0.76
1989 Broermann DM, Xie S, Nephew KP, Pope WF. Effects of the oviduct and wheat germ agglutinin on enzymatic digestion of porcine zona pellucidae. Journal of Animal Science. 67: 1324-9. PMID 2661516 DOI: 10.2527/jas1989.6751324x  0.76
1989 Nephew KP, Ford SP, Day ML, Pope WF. Extension of short cycles in postpartum beef cows by intrauterine treatment with catecholestradiol. Domestic Animal Endocrinology. 6: 363-70. PMID 2620506 DOI: 10.1016/0739-7240(89)90030-1  0.76
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