Daved H. Fremont - Publications

1998- Pathology and Immunology Washington University, Saint Louis, St. Louis, MO 
Immunology, General Biophysics, Biochemistry

127 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zhao H, Xu L, Bombardi R, Nargi R, Deng Z, Errico JM, Nelson CA, Dowd KA, Pierson TC, Crowe JE, Diamond MS, Fremont DH. Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge. The Journal of Experimental Medicine. PMID 31757867 DOI: 10.1084/jem.20191792  1
2019 Wang X, Piersma SJ, Elliott JI, Errico JM, Gainey MD, Yang L, Nelson CA, Yokoyama WM, Fremont DH. Cowpox virus encodes a protein that binds B7.1 and B7.2 and subverts T cell costimulation. Proceedings of the National Academy of Sciences of the United States of America. PMID 31575740 DOI: 10.1073/pnas.1909414116  1
2019 Hassan AO, Dmitriev IP, Kashentseva EA, Zhao H, Brough DE, Fremont DH, Curiel DT, Diamond MS. A Gorilla Adenovirus-Based Vaccine against Zika Virus Induces Durable Immunity and Confers Protection in Pregnancy. Cell Reports. 28: 2634-2646.e4. PMID 31484074 DOI: 10.1016/j.celrep.2019.08.005  1
2019 Earnest JT, Basore K, Roy V, Bailey AL, Wang D, Alter G, Fremont DH, Diamond MS. Neutralizing antibodies against Mayaro virus require Fc effector functions for protective activity. The Journal of Experimental Medicine. PMID 31337735 DOI: 10.1084/jem.20190736  1
2019 Basore K, Kim AS, Nelson CA, Zhang R, Smith BK, Uranga C, Vang L, Cheng M, Gross ML, Smith J, Diamond MS, Fremont DH. Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor. Cell. PMID 31080061 DOI: 10.1016/j.cell.2019.04.006  1
2019 Fox JM, Roy V, Gunn BM, Huang L, Edeling MA, Mack M, Fremont DH, Doranz BJ, Johnson S, Alter G, Diamond MS. Optimal therapeutic activity of monoclonal antibodies against chikungunya virus requires Fc-FcγR interaction on monocytes. Science Immunology. 4. PMID 30796092 DOI: 10.1126/sciimmunol.aav5062  1
2019 Salazar V, Jagger BW, Mongkolsapaya J, Burgomaster KE, Dejnirattisai W, Winkler ES, Fernandez E, Nelson CA, Fremont DH, Pierson TC, Crowe JE, Screaton GR, Diamond MS. Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice. Cell Reports. 26: 1585-1597.e4. PMID 30726740 DOI: 10.1016/j.celrep.2019.01.052  1
2018 Wang X, Piersma SJ, Christopher NA, Dia YN, Christensen T, Lazear E, Yang L, Sluijter M, van Hall T, Hansen TH, Yokoyama WM, Fremont DH. A herpesvirus encoded Qa-1 mimic inhibits natural killer cell cytotoxicity through CD94/NKG2A receptor engagement. Elife. 7. PMID 30575523 DOI: 10.7554/eLife.38667  0.32
2018 Kim AS, Austin SK, Gardner CL, Zuiani A, Reed DS, Trobaugh DW, Sun C, Basore K, Williamson LE, Crowe JE, Slifka MK, Fremont DH, Klimstra WB, Diamond MS. Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 glycoprotein. Nature Microbiology. PMID 30455470 DOI: 10.1038/s41564-018-0286-4  1
2018 Nelson CA, Wilen CB, Dai YN, Orchard RC, Kim AS, Stegeman RA, Hsieh LL, Smith TJ, Virgin HW, Fremont DH. Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor. Proceedings of the National Academy of Sciences of the United States of America. PMID 30194229 DOI: 10.1073/pnas.1805797115  1
2018 Zhang R, Kim AS, Fox JM, Nair S, Basore K, Klimstra WB, Rimkunas R, Fong RH, Lin H, Poddar S, Crowe JE, Doranz BJ, Fremont DH, Diamond MS. Mxra8 is a receptor for multiple arthritogenic alphaviruses. Nature. PMID 29769725 DOI: 10.1038/s41586-018-0121-3  1
2018 Fernandez E, Kose N, Edeling MA, Adhikari J, Sapparapu G, Lazarte SM, Nelson CA, Govero J, Gross ML, Fremont DH, Crowe JE, Diamond MS. Mouse and Human Monoclonal Antibodies Protect against Infection by Multiple Genotypes of Japanese Encephalitis Virus. Mbio. 9. PMID 29487230 DOI: 10.1128/mBio.00008-18  1
2018 Scott JM, Lebratti TJ, Richner JM, Jiang X, Fernandez E, Zhao H, Fremont DH, Diamond MS, Shin H. Cellular and Humoral Immunity Protect against Vaginal Zika Virus Infection in Mice. Journal of Virology. PMID 29343577 DOI: 10.1128/JVI.00038-18  1
2017 Barrow AD, Edeling MA, Trifonov V, Luo J, Goyal P, Bohl B, Bando JK, Kim AH, Walker J, Andahazy M, Bugatti M, Melocchi L, Vermi W, Fremont DH, Cox S, et al. Natural Killer Cells Control Tumor Growth by Sensing a Growth Factor. Cell. PMID 29275861 DOI: 10.1016/j.cell.2017.11.037  0.32
2016 Sapparapu G, Fernandez E, Kose N, Cao B, Fox JM, Bombardi RG, Zhao H, Nelson CA, Bryan AL, Barnes T, Davidson E, Mysorekar IU, Fremont DH, Doranz BJ, Diamond MS, et al. Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice. Nature. PMID 27819683 DOI: 10.1038/nature20564  1
2016 Zuiani A, Chen K, Schwarz MC, White JP, Luca VC, Fremont DH, Wang D, Evans MJ, Diamond MS. An E2 gene infectious HCV library reveals growth adaptive mutations that modulate interactions with the scavenger receptor class B type I. Journal of Virology. PMID 27630236 DOI: 10.1128/JVI.01011-16  1
2016 Orchard RC, Wilen CB, Doench JG, Baldridge MT, McCune BT, Lee YJ, Lee S, Pruett-Miller SM, Nelson CA, Fremont DH, Virgin HW. Discovery of a proteinaceous cellular receptor for a norovirus. Science (New York, N.Y.). PMID 27540007 DOI: 10.1126/science.aaf1220  1
2016 Zhao H, Fernandez E, Dowd KA, Speer SD, Platt DJ, Gorman MJ, Govero J, Nelson CA, Pierson TC, Diamond MS, Fremont DH. Structural Basis of Zika Virus-Specific Antibody Protection. Cell. PMID 27475895 DOI: 10.1016/j.cell.2016.07.020  1
2016 Lubman OY, Fremont DH. Parallel Evolution of Chemokine Binding by Structurally Related Herpesvirus Decoy Receptors. Structure (London, England : 1993). 24: 57-69. PMID 26671708 DOI: 10.1016/j.str.2015.10.018  1
2015 Fox JM, Long F, Edeling MA, Lin H, van Duijl-Richter MK, Fong RH, Kahle KM, Smit JM, Jin J, Simmons G, Doranz BJ, Crowe JE, Fremont DH, Rossmann MG, Diamond MS. Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress. Cell. PMID 26553503 DOI: 10.1016/j.cell.2015.10.050  1
2015 Nelson CA, Epperson ML, Singh S, Elliott JI, Fremont DH. Structural Conservation and Functional Diversity of the Poxvirus Immune Evasion (PIE) Domain Superfamily. Viruses. 7: 4878-98. PMID 26343707 DOI: 10.3390/v7092848  1
2015 Sakala IG, Kjer-Nielsen L, Eickhoff CS, Wang X, Blazevic A, Liu L, Fairlie DP, Rossjohn J, McCluskey J, Fremont DH, Hansen TH, Hoft DF. Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites. Journal of Immunology (Baltimore, Md. : 1950). 195: 587-601. PMID 26063000 DOI: 10.4049/jimmunol.1402545  1
2015 Warren JT, Zou W, Decker CE, Rohatgi N, Nelson CA, Fremont DH, Teitelbaum SL. Correlating RANK Ligand/RANK Binding Kinetics with Osteoclast Formation and Function. Journal of Cellular Biochemistry. PMID 25864714 DOI: 10.1002/jcb.25191  1
2014 Warren JT, Nelson CA, Decker CE, Zou W, Fremont DH, Teitelbaum SL. Manipulation of receptor oligomerization as a strategy to inhibit signaling by TNF superfamily members. Science Signaling. 7: ra80. PMID 25140055 DOI: 10.1126/scisignal.2004948  1
2014 Edeling MA, Austin SK, Shrestha B, Dowd KA, Mukherjee S, Nelson CA, Johnson S, Mabila MN, Christian EA, Rucker J, Pierson TC, Diamond MS, Fremont DH. Potent dengue virus neutralization by a therapeutic antibody with low monovalent affinity requires bivalent engagement. Plos Pathogens. 10: e1004072. PMID 24743696 DOI: 10.1371/journal.ppat.1004072  1
2014 Edeling MA, Diamond MS, Fremont DH. Structural basis of Flavivirus NS1 assembly and antibody recognition. Proceedings of the National Academy of Sciences of the United States of America. 111: 4285-90. PMID 24594604 DOI: 10.1073/pnas.1322036111  1
2014 Nelson CA, Lee CA, Fremont DH. Oxidative refolding from inclusion bodies. Methods in Molecular Biology (Clifton, N.J.). 1140: 145-57. PMID 24590715 DOI: 10.1007/978-1-4939-0354-2_11  1
2014 Nelson CA, McCoy WH, Fremont DH. Eukaryotic expression systems for structural studies. Methods in Molecular Biology (Clifton, N.J.). 1140: 107-16. PMID 24590712 DOI: 10.1007/978-1-4939-0354-2_8  1
2014 Fortin JS, Genève L, Gauthier C, Shoukry NH, Azar GA, Younes S, Yassine-Diab B, Sékaly RP, Fremont DH, Thibodeau J. MMTV superantigens coerce an unconventional topology between the TCR and MHC class II. Journal of Immunology (Baltimore, Md. : 1950). 192: 1896-906. PMID 24453254 DOI: 10.4049/jimmunol.1203130  1
2014 Lubman OY, Cella M, Wang X, Monte K, Lenschow DJ, Huang YH, Fremont DH. Rodent herpesvirus Peru encodes a secreted chemokine decoy receptor. Journal of Virology. 88: 538-46. PMID 24173234 DOI: 10.1128/JVI.02729-13  1
2013 Lee PD, Mukherjee S, Edeling MA, Dowd KA, Austin SK, Manhart CJ, Diamond MS, Fremont DH, Pierson TC. The Fc region of an antibody impacts the neutralization of West Nile viruses in different maturation states. Journal of Virology. 87: 13729-40. PMID 24109224 DOI: 10.1128/JVI.02340-13  1
2013 Skillman KM, Ma CI, Fremont DH, Diraviyam K, Cooper JA, Sept D, Sibley LD. The unusual dynamics of parasite actin result from isodesmic polymerization. Nature Communications. 4: 2285. PMID 23921463 DOI: 10.1038/ncomms3285  1
2013 Sukupolvi-Petty S, Brien JD, Austin SK, Shrestha B, Swayne S, Kahle K, Doranz BJ, Johnson S, Pierson TC, Fremont DH, Diamond MS. Functional analysis of antibodies against dengue virus type 4 reveals strain-dependent epitope exposure that impacts neutralization and protection. Journal of Virology. 87: 8826-42. PMID 23785205 DOI: 10.1128/JVI.01314-13  1
2013 Pal P, Dowd KA, Brien JD, Edeling MA, Gorlatov S, Johnson S, Lee I, Akahata W, Nabel GJ, Richter MK, Smit JM, Fremont DH, Pierson TC, Heise MT, Diamond MS. Development of a highly protective combination monoclonal antibody therapy against Chikungunya virus. Plos Pathogens. 9: e1003312. PMID 23637602 DOI: 10.1371/journal.ppat.1003312  1
2013 Zhou Y, Austin SK, Fremont DH, Yount BL, Huynh JP, de Silva AM, Baric RS, Messer WB. The mechanism of differential neutralization of dengue serotype 3 strains by monoclonal antibody 8A1 Virology. 439: 57-64. PMID 23453578 DOI: 10.1016/j.virol.2013.01.022  1
2013 McCoy WH, Wang X, Yokoyama WM, Hansen TH, Fremont DH. Cowpox virus employs a two-pronged strategy to outflank MHCI antigen presentation. Molecular Immunology. 55: 156-8. PMID 23312338 DOI: 10.1016/j.molimm.2012.11.011  0.32
2013 Luca VC, Nelson CA, Fremont DH. Structure of the St. Louis encephalitis virus postfusion envelope trimer. Journal of Virology. 87: 818-28. PMID 23115296 DOI: 10.1128/JVI.01950-12  1
2013 Lazear E, Peterson LW, Nelson CA, Fremont DH. Crystal structure of the cowpox virus-encoded NKG2D ligand OMCP. Journal of Virology. 87: 840-50. PMID 23115291 DOI: 10.1128/JVI.01948-12  1
2012 McCoy WH, Wang X, Yokoyama WM, Hansen TH, Fremont DH. Structural mechanism of ER retrieval of MHC class I by cowpox. Plos Biology. 10: e1001432. PMID 23209377 DOI: 10.1371/journal.pbio.1001432  0.32
2012 Banchereau J, Zurawski S, Thompson-Snipes L, Blanck JP, Clayton S, Munk A, Cao Y, Wang Z, Khandelwal S, Hu J, McCoy WH, Palucka KA, Reiter Y, Fremont DH, Zurawski G, et al. Immunoglobulin-like transcript receptors on human dermal CD14+ dendritic cells act as a CD8-antagonist to control cytotoxic T cell priming. Proceedings of the National Academy of Sciences of the United States of America. 109: 18885-90. PMID 23112154 DOI: 10.1073/pnas.1205785109  1
2012 Austin SK, Dowd KA, Shrestha B, Nelson CA, Edeling MA, Johnson S, Pierson TC, Diamond MS, Fremont DH. Structural basis of differential neutralization of DENV-1 genotypes by an antibody that recognizes a cryptic epitope. Plos Pathogens. 8: e1002930. PMID 23055922 DOI: 10.1371/journal.ppat.1002930  1
2012 Nelson CA, Warren JT, Wang MW, Teitelbaum SL, Fremont DH. RANKL employs distinct binding modes to engage RANK and the osteoprotegerin decoy receptor. Structure (London, England : 1993). 20: 1971-82. PMID 23039992 DOI: 10.1016/j.str.2012.08.030  1
2012 Youn S, Li T, McCune BT, Edeling MA, Fremont DH, Cristea IM, Diamond MS. Evidence for a genetic and physical interaction between nonstructural proteins NS1 and NS4B that modulates replication of West Nile virus. Journal of Virology. 86: 7360-71. PMID 22553322 DOI: 10.1128/JVI.00157-12  1
2012 Shrestha B, Austin SK, Dowd KA, Prasad AN, Youn S, Pierson TC, Fremont DH, Ebel GD, Diamond MS. Complex phenotypes in mosquitoes and mice associated with neutralization escape of a Dengue virus type 1 monoclonal antibody. Virology. 427: 127-34. PMID 22406169 DOI: 10.1016/j.virol.2012.02.010  1
2012 Luca VC, AbiMansour J, Nelson CA, Fremont DH. Crystal structure of the Japanese encephalitis virus envelope protein. Journal of Virology. 86: 2337-46. PMID 22156523 DOI: 10.1128/JVI.06072-11  1
2012 Sabo MC, Luca VC, Ray SC, Bukh J, Fremont DH, Diamond MS. Hepatitis C virus epitope exposure and neutralization by antibodies is affected by time and temperature. Virology. 422: 174-84. PMID 22078164 DOI: 10.1016/j.virol.2011.10.023  1
2011 Riboldi E, Daniele R, Parola C, Inforzato A, Arnold PL, Bosisio D, Fremont DH, Bastone A, Colonna M, Sozzani S. Human C-type lectin domain family 4, member C (CLEC4C/BDCA-2/CD303) is a receptor for asialo-galactosyl-oligosaccharides. The Journal of Biological Chemistry. 286: 35329-33. PMID 21880719 DOI: 10.1074/jbc.C111.290494  1
2011 Sabo MC, Luca VC, Prentoe J, Hopcraft SE, Blight KJ, Yi M, Lemon SM, Ball JK, Bukh J, Evans MJ, Fremont DH, Diamond MS. Neutralizing monoclonal antibodies against hepatitis C virus E2 protein bind discontinuous epitopes and inhibit infection at a postattachment step. Journal of Virology. 85: 7005-19. PMID 21543495 DOI: 10.1128/JVI.00586-11  1
2011 Chua WJ, Kim S, Myers N, Huang S, Yu L, Fremont DH, Diamond MS, Hansen TH. Endogenous MHC-related protein 1 is transiently expressed on the plasma membrane in a conformation that activates mucosal-associated invariant T cells. Journal of Immunology (Baltimore, Md. : 1950). 186: 4744-50. PMID 21402896 DOI: 10.4049/jimmunol.1003254  1
2011 Loh J, Zhao G, Nelson CA, Coder P, Droit L, Handley SA, Johnson LS, Vachharajani P, Guzman H, Tesh RB, Wang D, Fremont DH, Virgin HW. Identification and sequencing of a novel rodent gammaherpesvirus that establishes acute and latent infection in laboratory mice. Journal of Virology. 85: 2642-56. PMID 21209105 DOI: 10.1128/JVI.01661-10  1
2011 Swiecki M, Scheaffer SM, Allaire M, Fremont DH, Colonna M, Brett TJ. Structural and biophysical analysis of BST-2/tetherin ectodomains reveals an evolutionary conserved design to inhibit virus release. The Journal of Biological Chemistry. 286: 2987-97. PMID 21084286 DOI: 10.1074/jbc.M110.190538  0.48
2010 Hansen TH, Connolly JM, Gould KG, Fremont DH. Basic and translational applications of engineered MHC class I proteins. Trends in Immunology. 31: 363-9. PMID 20832361 DOI: 10.1016/j.it.2010.07.003  1
2010 Brien JD, Austin SK, Sukupolvi-Petty S, O'Brien KM, Johnson S, Fremont DH, Diamond MS. Genotype-specific neutralization and protection by antibodies against dengue virus type 3. Journal of Virology. 84: 10630-43. PMID 20702644 DOI: 10.1128/JVI.01190-10  1
2010 Youn S, Cho H, Fremont DH, Diamond MS. A short N-terminal peptide motif on flavivirus nonstructural protein NS1 modulates cellular targeting and immune recognition. Journal of Virology. 84: 9516-32. PMID 20592095 DOI: 10.1128/JVI.00775-10  1
2010 Sukupolvi-Petty S, Austin SK, Engle M, Brien JD, Dowd KA, Williams KL, Johnson S, Rico-Hesse R, Harris E, Pierson TC, Fremont DH, Diamond MS. Structure and function analysis of therapeutic monoclonal antibodies against dengue virus type 2. Journal of Virology. 84: 9227-39. PMID 20592088 DOI: 10.1128/JVI.01087-10  1
2010 Campbell JA, Davis RS, Lilly LM, Fremont DH, French AR, Carayannopoulos LN. Cutting edge: FcR-like 5 on innate B cells is targeted by a poxvirus MHC class I-like immunoevasin. Journal of Immunology (Baltimore, Md. : 1950). 185: 28-32. PMID 20519648 DOI: 10.4049/jimmunol.1000240  1
2010 Shrestha B, Brien JD, Sukupolvi-Petty S, Austin SK, Edeling MA, Kim T, O'Brien KM, Nelson CA, Johnson S, Fremont DH, Diamond MS. The development of therapeutic antibodies that neutralize homologous and heterologous genotypes of dengue virus type 1. Plos Pathogens. 6: e1000823. PMID 20369024 DOI: 10.1371/journal.ppat.1000823  1
2009 Kaufmann B, Chipman PR, Holdaway HA, Johnson S, Fremont DH, Kuhn RJ, Diamond MS, Rossmann MG. Capturing a flavivirus pre-fusion intermediate. Plos Pathogens. 5: e1000672. PMID 19956725 DOI: 10.1371/journal.ppat.1000672  1
2009 Mehlhop E, Nelson S, Jost CA, Gorlatov S, Johnson S, Fremont DH, Diamond MS, Pierson TC. Complement protein C1q reduces the stoichiometric threshold for antibody-mediated neutralization of West Nile virus. Cell Host & Microbe. 6: 381-91. PMID 19837377 DOI: 10.1016/j.chom.2009.09.003  1
2009 Cherrier MV, Kaufmann B, Nybakken GE, Lok SM, Warren JT, Chen BR, Nelson CA, Kostyuchenko VA, Holdaway HA, Chipman PR, Kuhn RJ, Diamond MS, Rossmann MG, Fremont DH. Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody. The Embo Journal. 28: 3269-76. PMID 19713934 DOI: 10.1038/emboj.2009.245  1
2009 Wahl A, McCoy W, Schafer F, Bardet W, Buchli R, Fremont DH, Hildebrand WH. T-cell tolerance for variability in an HLA class I-presented influenza A virus epitope. Journal of Virology. 83: 9206-14. PMID 19553306 DOI: 10.1128/JVI.00932-09  1
2009 Thompson BS, Moesker B, Smit JM, Wilschut J, Diamond MS, Fremont DH. A therapeutic antibody against west nile virus neutralizes infection by blocking fusion within endosomes. Plos Pathogens. 5: e1000453. PMID 19478866 DOI: 10.1371/journal.ppat.1000453  1
2009 Huang S, Martin E, Kim S, Yu L, Soudais C, Fremont DH, Lantz O, Hansen TH. MR1 antigen presentation to mucosal-associated invariant T cells was highly conserved in evolution. Proceedings of the National Academy of Sciences of the United States of America. 106: 8290-5. PMID 19416870 DOI: 10.1073/pnas.0903196106  0.32
2008 Diamond MS, Pierson TC, Fremont DH. The structural immunology of antibody protection against West Nile virus. Immunological Reviews. 225: 212-25. PMID 18837784 DOI: 10.1111/j.1600-065X.2008.00676.x  1
2008 Pierson TC, Fremont DH, Kuhn RJ, Diamond MS. Structural insights into the mechanisms of antibody-mediated neutralization of flavivirus infection: implications for vaccine development. Cell Host & Microbe. 4: 229-38. PMID 18779049 DOI: 10.1016/j.chom.2008.08.004  1
2008 Diamond MS, Fremont DH. Ebola images emerge from the cave. Cell Host & Microbe. 4: 87-9. PMID 18692765 DOI: 10.1016/j.chom.2008.07.011  1
2008 Huang S, Gilfillan S, Kim S, Thompson B, Wang X, Sant AJ, Fremont DH, Lantz O, Hansen TH. MR1 uses an endocytic pathway to activate mucosal-associated invariant T cells. The Journal of Experimental Medicine. 205: 1201-11. PMID 18443227 DOI: 10.1084/jem.20072579  1
2008 Tomasson MH, Xiang Z, Walgren R, Zhao Y, Kasai Y, Miner T, Ries RE, Lubman O, Fremont DH, McLellan MD, Payton JE, Westervelt P, DiPersio JF, Link DC, Walter MJ, et al. Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia. Blood. 111: 4797-808. PMID 18270328 DOI: 10.1182/blood-2007-09-113027  1
2008 Lok SM, Kostyuchenko V, Nybakken GE, Holdaway HA, Battisti AJ, Sukupolvi-Petty S, Sedlak D, Fremont DH, Chipman PR, Roehrig JT, Diamond MS, Kuhn RJ, Rossmann MG. Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins. Nature Structural & Molecular Biology. 15: 312-7. PMID 18264114 DOI: 10.1038/nsmb.1382  1
2008 Truscott SM, Wang X, Lybarger L, Biddison WE, McBerry C, Martinko JM, Connolly JM, Linette GP, Fremont DH, Hansen TH, Carreno BM. Human major histocompatibility complex (MHC) class I molecules with disulfide traps secure disease-related antigenic peptides and exclude competitor peptides. The Journal of Biological Chemistry. 283: 7480-90. PMID 18195006 DOI: 10.1074/jbc.M709935200  1
2008 Nelson CA, Fremont MD, Sedy JR, Norris PS, Ware CF, Murphy KM, Fremont DH. Structural determinants of herpesvirus entry mediator recognition by murine B and T lymphocyte attenuator. Journal of Immunology (Baltimore, Md. : 1950). 180: 940-7. PMID 18178834  1
2008 Xiang Z, Zhao Y, Mitaksov V, Fremont DH, Kasai Y, Molitoris A, Ries RE, Miner TL, McLellan MD, DiPersio JF, Link DC, Payton JE, Graubert TA, Watson M, Shannon W, et al. Identification of somatic JAK1 mutations in patients with acute myeloid leukemia. Blood. 111: 4809-12. PMID 18160671 DOI: 10.1182/blood-2007-05-090308  1
2007 Mehlhop E, Ansarah-Sobrinho C, Johnson S, Engle M, Fremont DH, Pierson TC, Diamond MS. Complement protein C1q inhibits antibody-dependent enhancement of flavivirus infection in an IgG subclass-specific manner. Cell Host & Microbe. 2: 417-26. PMID 18078693 DOI: 10.1016/j.chom.2007.09.015  1
2007 Alexander-Brett JM, Fremont DH. Dual GPCR and GAG mimicry by the M3 chemokine decoy receptor. The Journal of Experimental Medicine. 204: 3157-72. PMID 18070938 DOI: 10.1084/jem.20071677  1
2007 Pierson TC, Xu Q, Nelson S, Oliphant T, Nybakken GE, Fremont DH, Diamond MS. The stoichiometry of antibody-mediated neutralization and enhancement of West Nile virus infection. Cell Host & Microbe. 1: 135-45. PMID 18005691 DOI: 10.1016/j.chom.2007.03.002  1
2007 Sukupolvi-Petty S, Austin SK, Purtha WE, Oliphant T, Nybakken GE, Schlesinger JJ, Roehrig JT, Gromowski GD, Barrett AD, Fremont DH, Diamond MS. Type- and subcomplex-specific neutralizing antibodies against domain III of dengue virus type 2 envelope protein recognize adjacent epitopes. Journal of Virology. 81: 12816-26. PMID 17881453 DOI: 10.1128/JVI.00432-07  1
2007 Mitaksov V, Truscott SM, Lybarger L, Connolly JM, Hansen TH, Fremont DH. Structural engineering of pMHC reagents for T cell vaccines and diagnostics. Chemistry & Biology. 14: 909-22. PMID 17719490 DOI: 10.1016/j.chembiol.2007.07.010  1
2007 Oliphant T, Nybakken GE, Austin SK, Xu Q, Bramson J, Loeb M, Throsby M, Fremont DH, Pierson TC, Diamond MS. Induction of epitope-specific neutralizing antibodies against West Nile virus. Journal of Virology. 81: 11828-39. PMID 17715236 DOI: 10.1128/JVI.00643-07  1
2007 Chung KM, Thompson BS, Fremont DH, Diamond MS. Antibody recognition of cell surface-associated NS1 triggers Fc-gamma receptor-mediated phagocytosis and clearance of West Nile Virus-infected cells. Journal of Virology. 81: 9551-5. PMID 17582005 DOI: 10.1128/JVI.00879-07  1
2007 Purtha WE, Myers N, Mitaksov V, Sitati E, Connolly J, Fremont DH, Hansen TH, Diamond MS. Antigen-specific cytotoxic T lymphocytes protect against lethal West Nile virus encephalitis. European Journal of Immunology. 37: 1845-54. PMID 17559174 DOI: 10.1002/eji.200737192  1
2007 Hansen TH, Huang S, Arnold PL, Fremont DH. Patterns of nonclassical MHC antigen presentation. Nature Immunology. 8: 563-8. PMID 17514210 DOI: 10.1038/ni1475  1
2007 Truscott SM, Lybarger L, Martinko JM, Mitaksov VE, Kranz DM, Connolly JM, Fremont DH, Hansen TH. Disulfide bond engineering to trap peptides in the MHC class I binding groove. Journal of Immunology (Baltimore, Md. : 1950). 178: 6280-9. PMID 17475856  1
2007 Martin AP, Alexander-Brett JM, Canasto-Chibuque C, Garin A, Bromberg JS, Fremont DH, Lira SA. The chemokine binding protein M3 prevents diabetes induced by multiple low doses of streptozotocin. Journal of Immunology (Baltimore, Md. : 1950). 178: 4623-31. PMID 17372021  1
2006 Chung KM, Liszewski MK, Nybakken G, Davis AE, Townsend RR, Fremont DH, Atkinson JP, Diamond MS. West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H. Proceedings of the National Academy of Sciences of the United States of America. 103: 19111-6. PMID 17132743 DOI: 10.1073/pnas.0605668103  1
2006 Pekosz A, Schaecher SR, Diamond MS, Fremont DH, Sims AC, Baric RS. Structure, expression, and intracellular localization of the SARS-CoV accessory proteins 7a and 7b. Advances in Experimental Medicine and Biology. 581: 115-20. PMID 17037516 DOI: 10.1007/978-0-387-33012-9_20  1
2006 Oliphant T, Nybakken GE, Engle M, Xu Q, Nelson CA, Sukupolvi-Petty S, Marri A, Lachmi BE, Olshevsky U, Fremont DH, Pierson TC, Diamond MS. Antibody recognition and neutralization determinants on domains I and II of West Nile Virus envelope protein. Journal of Virology. 80: 12149-59. PMID 17035317 DOI: 10.1128/JVI.01732-06  1
2006 Nybakken GE, Nelson CA, Chen BR, Diamond MS, Fremont DH. Crystal structure of the West Nile virus envelope glycoprotein. Journal of Virology. 80: 11467-74. PMID 16987985 DOI: 10.1128/JVI.01125-06  1
2006 Kaufmann B, Nybakken GE, Chipman PR, Zhang W, Diamond MS, Fremont DH, Kuhn RJ, Rossmann MG. West Nile virus in complex with the Fab fragment of a neutralizing monoclonal antibody. Proceedings of the National Academy of Sciences of the United States of America. 103: 12400-4. PMID 16895988 DOI: 10.1073/pnas.0603488103  1
2006 Arnold PL, Fremont DH. Structural determinants of chemokine binding by an Ectromelia virus-encoded decoy receptor. Journal of Virology. 80: 7439-49. PMID 16840324 DOI: 10.1128/JVI.00576-06  1
2006 Brett TJ, Legendre-Guillemin V, McPherson PS, Fremont DH. Structural definition of the F-actin-binding THATCH domain from HIP1R. Nature Structural & Molecular Biology. 13: 121-30. PMID 16415883 DOI: 10.1038/nsmb1043  0.48
2006 Chung KM, Nybakken GE, Thompson BS, Engle MJ, Marri A, Fremont DH, Diamond MS. Antibodies against West Nile Virus nonstructural protein NS1 prevent lethal infection through Fc gamma receptor-dependent and -independent mechanisms. Journal of Virology. 80: 1340-51. PMID 16415011 DOI: 10.1128/JVI.80.3.1340-1351.2006  1
2005 Nybakken GE, Oliphant T, Johnson S, Burke S, Diamond MS, Fremont DH. Structural basis of West Nile virus neutralization by a therapeutic antibody. Nature. 437: 764-9. PMID 16193056 DOI: 10.1038/nature03956  1
2005 Hansen TH, Lybarger L, Yu L, Mitaksov V, Fremont DH. Recognition of open conformers of classical MHC by chaperones and monoclonal antibodies. Immunological Reviews. 207: 100-11. PMID 16181330 DOI: 10.1111/j.0105-2896.2005.00315.x  0.32
2005 Markiewicz MA, Carayannopoulos LN, Naidenko OV, Matsui K, Burack WR, Wise EL, Fremont DH, Allen PM, Yokoyama WM, Colonna M, Shaw AS. Costimulation through NKG2D enhances murine CD8+ CTL function: similarities and differences between NKG2D and CD28 costimulation. Journal of Immunology (Baltimore, Md. : 1950). 175: 2825-33. PMID 16116168  1
2005 Oliphant T, Engle M, Nybakken GE, Doane C, Johnson S, Huang L, Gorlatov S, Mehlhop E, Marri A, Chung KM, Ebel GD, Kramer LD, Fremont DH, Diamond MS. Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus. Nature Medicine. 11: 522-30. PMID 15852016 DOI: 10.1038/nm1240  1
2005 Huang S, Gilfillan S, Cella M, Miley MJ, Lantz O, Lybarger L, Fremont DH, Hansen TH. Evidence for MR1 antigen presentation to mucosal-associated invariant T cells. The Journal of Biological Chemistry. 280: 21183-93. PMID 15802267 DOI: 10.1074/jbc.M501087200  1
2005 Nelson CA, Pekosz A, Lee CA, Diamond MS, Fremont DH. Structure and intracellular targeting of the SARS-coronavirus Orf7a accessory protein. Structure (London, England : 1993). 13: 75-85. PMID 15642263 DOI: 10.1016/j.str.2004.10.010  1
2004 Miley MJ, Messaoudi I, Metzner BM, Wu Y, Nikolich-Zugich J, Fremont DH. Structural basis for the restoration of TCR recognition of an MHC allelic variant by peptide secondary anchor substitution. The Journal of Experimental Medicine. 200: 1445-54. PMID 15557346 DOI: 10.1084/jem.20040217  1
2004 Mishra SK, Hawryluk MJ, Brett TJ, Keyel PA, Dupin AL, Jha A, Heuser JE, Fremont DH, Traub LM. Dual engagement regulation of protein interactions with the AP-2 adaptor alpha appendage. The Journal of Biological Chemistry. 279: 46191-203. PMID 15292237 DOI: 10.1074/jbc.M408095200  1
2004 Nikolich-Zugich J, Fremont DH, Miley MJ, Messaoudi I. The role of mhc polymorphism in anti-microbial resistance. Microbes and Infection / Institut Pasteur. 6: 501-12. PMID 15109966 DOI: 10.1016/j.micinf.2004.01.006  1
2004 Ota N, Brett TJ, Murphy TL, Fremont DH, Murphy KM. N-domain-dependent nonphosphorylated STAT4 dimers required for cytokine-driven activation. Nature Immunology. 5: 208-15. PMID 14704793 DOI: 10.1038/ni1032  0.48
2003 Miley MJ, Truscott SM, Yu YY, Gilfillan S, Fremont DH, Hansen TH, Lybarger L. Biochemical features of the MHC-related protein 1 consistent with an immunological function. Journal of Immunology (Baltimore, Md. : 1950). 170: 6090-8. PMID 12794138  1
2003 Lybarger L, Yu YY, Miley MJ, Fremont DH, Myers N, Primeau T, Truscott SM, Connolly JM, Hansen TH. Enhanced immune presentation of a single-chain major histocompatibility complex class I molecule engineered to optimize linkage of a C-terminally extended peptide. The Journal of Biological Chemistry. 278: 27105-11. PMID 12732632 DOI: 10.1074/jbc.M303716200  1
2002 Alexander JM, Nelson CA, van Berkel V, Lau EK, Studts JM, Brett TJ, Speck SH, Handel TM, Virgin HW, Fremont DH. Structural basis of chemokine sequestration by a herpesvirus decoy receptor. Cell. 111: 343-56. PMID 12419245 DOI: 10.1016/S0092-8674(02)01007-3  1
2002 Lam J, Abu-Amer Y, Nelson CA, Fremont DH, Ross FP, Teitelbaum SL. Tumour necrosis factor superfamily cytokines and the pathogenesis of inflammatory osteolysis. Annals of the Rheumatic Diseases. 61: ii82-3. PMID 12379631  1
2002 Smith HR, Heusel JW, Mehta IK, Kim S, Dorner BG, Naidenko OV, Iizuka K, Furukawa H, Beckman DL, Pingel JT, Scalzo AA, Fremont DH, Yokoyama WM. Recognition of a virus-encoded ligand by a natural killer cell activation receptor. Proceedings of the National Academy of Sciences of the United States of America. 99: 8826-31. PMID 12060703 DOI: 10.1073/pnas.092258599  1
2002 Brett TJ, Traub LM, Fremont DH. Accessory protein recruitment motifs in clathrin-mediated endocytosis. Structure (London, England : 1993). 10: 797-809. PMID 12057195  0.48
2002 Fremont DH, Dai S, Chiang H, Crawford F, Marrack P, Kappler J. Structural basis of cytochrome c presentation by IE(k). The Journal of Experimental Medicine. 195: 1043-52. PMID 11956295  1
2002 Facchetti F, Cella M, Festa S, Fremont DH, Colonna M. An unusual Fc receptor-related protein expressed in human centroblasts. Proceedings of the National Academy of Sciences of the United States of America. 99: 3776-81. PMID 11891275 DOI: 10.1073/pnas.022042699  0.32
2001 Lam J, Nelson CA, Ross FP, Teitelbaum SL, Fremont DH. Crystal structure of the TRANCE/RANKL cytokine reveals determinants of receptor-ligand specificity. The Journal of Clinical Investigation. 108: 971-9. PMID 11581298 DOI: 10.1172/JCI13890  1
2001 Messaoudi I, LeMaoult J, Metzner BM, Miley MJ, Fremont DH, Nikolich-Zugich J. Functional evidence that conserved TCR CDR alpha 3 loop docking governs the cross-recognition of closely related peptide:class I complexes. Journal of Immunology (Baltimore, Md. : 1950). 167: 836-43. PMID 11441090  1
2001 Kersh GJ, Miley MJ, Nelson CA, Grakoui A, Horvath S, Donermeyer DL, Kappler J, Allen PM, Fremont DH. Structural and functional consequences of altering a peptide MHC anchor residue. Journal of Immunology (Baltimore, Md. : 1950). 166: 3345-54. PMID 11207290  1
2000 Van Berkel V, Barrett J, Tiffany HL, Fremont DH, Murphy PM, Mcfadden G, Speck SH, Virgin IV HW. Identification of a gammaherpesvirus selective chemokine binding protein that inhibits chemokine action Journal of Virology. 74: 6741-6747. PMID 10888612 DOI: 10.1128/JVI.74.15.6741-6747.2000  1
2000 Basu D, Horvath S, Matsumoto I, Fremont DH, Allen PM. Molecular basis for recognition of an arthritic peptide and a foreign epitope on distinct MHC molecules by a single TCR. Journal of Immunology (Baltimore, Md. : 1950). 164: 5788-96. PMID 10820257  1
1999 Traub LM, Downs MA, Westrich JL, Fremont DH. Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly. Proceedings of the National Academy of Sciences of the United States of America. 96: 8907-12. PMID 10430869  0.48
1998 Fremont DH, Crawford F, Marrack P, Hendrickson WA, Kappler J. Crystal structure of mouse H2-M. Immunity. 9: 385-93. PMID 9768758 DOI: 10.1016/S1074-7613(00)80621-4  1
1998 Fremont DH, Monnaie D, Nelson CA, Hendrickson WA, Unanue ER. Crystal structure of I-Ak in complex with a dominant epitope of lysozyme. Immunity. 8: 305-17. PMID 9529148 DOI: 10.1016/S1074-7613(00)80536-1  1
1996 Fremont DH, Hendrickson WA, Marrack P, Kappler J. Structures of an MHC class II molecule with covalently bound single peptides. Science (New York, N.Y.). 272: 1001-4. PMID 8638119  1
1995 Fremont DH, Stura EA, Matsumura M, Peterson PA, Wilson IA. Crystal structure of an H-2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove Proceedings of the National Academy of Sciences of the United States of America. 92: 2479-2483. PMID 7708669 DOI: 10.1073/pnas.92.7.2479  1
1994 Wilson IA, Stanfield RL, Jewell DA, Ghiara JB, Fremont DH, Stura EA. Immune recognition of viral antigens Infectious Agents and Disease. 3: 155-162. PMID 7812653  1
1993 Wilson IA, Fremont DH. Structural analysis of MHC class I molecules with bound peptide antigens. Seminars in Immunology. 5: 75-80. PMID 8504218 DOI: 10.1006/smim.1993.1011  1
1993 Fremont DH, Anderson DH, Wilson IA, Dennis EA, Xuong NH. Crystal structure of phospholipase A2 from Indian cobra reveals a trimeric association. Proceedings of the National Academy of Sciences of the United States of America. 90: 342-6. PMID 8419939  1
1992 Stura EA, Matsumura M, Fremont DH, Saito Y, Peterson PA, Wilson LA. Crystallization of murine major histocompatibility complex class I H-2Kb with single peptides Journal of Molecular Biology. 228: 975-982. PMID 1469730 DOI: 10.1016/0022-2836(92)90881-J  1
1992 Matsumura M, Fremont DH, Peterson PA, Wilson IA. Emerging principles for the recognition of peptide antigens by MHC class I molecules Science. 257: 927-934. PMID 1323878  1
1992 Fremont DH, Matsumura M, Stura EA, Peterson PA, Wilson IA. Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb Science. 257: 919-927. PMID 1323877  1
1991 Wilson IA, Stanfield RL, Rini JM, Arevalo JH, Schulze-Gahmen U, Fremont DH, Stura EA. Structural aspects of antibodies and antibody-antigen complexes. Ciba Foundation Symposium. 159: 13-28; discussion 28. PMID 1959445  1
1991 Wilson IA, Rini JM, Fremont DH, Fieser GG, Stura EA. X-ray crystallographic analysis of free and antigen-complexed Fab fragments to investigate structural basis of immune recognition. Methods in Enzymology. 203: 153-76. PMID 1762555  1
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