Roxanne A. Vaughan - Publications

Affiliations: 
The University of North Dakota 
Area:
Biochemistry

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Bolland DE, Moritz AE, Stanislowski DJ, Vaughan DR, Foster JD. Palmitoylation by multiple DHHC enzymes enhances dopamine transporter function and stability. Acs Chemical Neuroscience. PMID 30965003 DOI: 10.1021/acschemneuro.8b00558  0.36
2018 Yang JW, Larson G, Konrad L, Shetty M, Holy M, Jäntsch K, Kastein M, Heo S, Erdem FA, Lubec G, Vaughan RA, Sitte HH, Foster JD. Dephosphorylation of human dopamine transporter at threonine 48 by protein phosphatase PP1/2A upregulates transport velocity. The Journal of Biological Chemistry. PMID 30587577 DOI: 10.1074/jbc.RA118.005251  0.72
2018 Hovde MJ, Larson GH, Vaughan RA, Foster JD. Model systems for analysis of dopamine transporter function and regulation. Neurochemistry International. PMID 30179648 DOI: 10.1016/j.neuint.2018.08.015  0.72
2017 Challasivakanaka S, Zhen J, Smith ME, Reith MEA, Foster JD, Vaughan RA. Dopamine Transporter Phosphorylation Site Threonine 53 is Stimulated by Amphetamines and Regulates Dopamine Transport, Efflux, and Cocaine Analog Binding. The Journal of Biological Chemistry. PMID 28939767 DOI: 10.1074/jbc.M117.787002  0.72
2017 Krout D, Pramod AB, Dahal RA, Tomlinson MJ, Sharma B, Foster JD, Zou MF, Boatang C, Newman AH, Lever JR, Vaughan RA, Henry LK. Inhibitor mechanisms in the S1 binding site of the dopamine transporter defined by multi-site molecular tethering of photoactive cocaine analogs. Biochemical Pharmacology. PMID 28734777 DOI: 10.1016/j.bcp.2017.07.015  0.72
2017 Rastedt DE, Vaughan RA, Foster JD. Palmitoylation mechanisms in dopamine transporter regulation. Journal of Chemical Neuroanatomy. PMID 28115272 DOI: 10.1016/j.jchemneu.2017.01.002  0.72
2016 Foster JD, Vaughan RA. Phosphorylation Mechanisms in Dopamine Transporter Regulation. Journal of Chemical Neuroanatomy. PMID 27836487 DOI: 10.1016/j.jchemneu.2016.10.004  0.72
2015 Moritz AE, Rastedt DE, Stanislowski DJ, Shetty M, Smith MA, Vaughan RA, Foster JD. Reciprocal Phosphorylation and Palmitoylation Control Dopamine Transporter Kinetics. The Journal of Biological Chemistry. PMID 26424792 DOI: 10.1074/jbc.M115.667055  1
2015 Kumar V, Yarravarapu N, Lapinsky DJ, Perley D, Felts B, Tomlinson MJ, Vaughan RA, Henry LK, Lever JR, Newman AH. Novel Azido-Iodo Photoaffinity Ligands for the Human Serotonin Transporter Based on the Selective Serotonin Reuptake Inhibitor (S)-Citalopram. Journal of Medicinal Chemistry. PMID 26153715 DOI: 10.1021/acs.jmedchem.5b00682  1
2014 Dahal RA, Pramod AB, Sharma B, Krout D, Foster JD, Cha JH, Cao J, Newman AH, Lever JR, Vaughan RA, Henry LK. Computational and biochemical docking of the irreversible cocaine analog RTI 82 directly demonstrates ligand positioning in the dopamine transporter central substrate-binding site. The Journal of Biological Chemistry. 289: 29712-27. PMID 25179220 DOI: 10.1074/jbc.M114.571521  1
2014 Gaffaney JD, Shetty M, Felts B, Pramod AB, Foster JD, Henry LK, Vaughan RA. Antagonist-induced conformational changes in dopamine transporter extracellular loop two involve residues in a potential salt bridge. Neurochemistry International. 73: 16-26. PMID 24269640 DOI: 10.1016/j.neuint.2013.11.003  1
2013 Vaughan RA, Foster JD. Mechanisms of dopamine transporter regulation in normal and disease states. Trends in Pharmacological Sciences. 34: 489-96. PMID 23968642 DOI: 10.1016/j.tips.2013.07.005  1
2013 Moritz AE, Foster JD, Gorentla BK, Mazei-Robison MS, Yang JW, Sitte HH, Blakely RD, Vaughan RA. Phosphorylation of dopamine transporter serine 7 modulates cocaine analog binding. The Journal of Biological Chemistry. 288: 20-32. PMID 23161550 DOI: 10.1074/jbc.M112.407874  1
2012 Lapinsky DJ, Yarravarapu N, Nolan TL, Surratt CK, Lever JR, Tomlinson M, Vaughan RA, Deutsch HM. Evolution of a Compact Photoprobe for the Dopamine Transporter Based on (±)-threo-Methylphenidate. Acs Medicinal Chemistry Letters. 3: 378-382. PMID 23066448 DOI: 10.1021/ml3000098  1
2012 Foster JD, Yang JW, Moritz AE, Challasivakanaka S, Smith MA, Holy M, Wilebski K, Sitte HH, Vaughan RA. Dopamine transporter phosphorylation site threonine 53 regulates substrate reuptake and amphetamine-stimulated efflux. The Journal of Biological Chemistry. 287: 29702-12. PMID 22722938 DOI: 10.1074/jbc.M112.367706  1
2012 Lapinsky DJ, Aggarwal S, Nolan TL, Surratt CK, Lever JR, Acharya R, Vaughan RA, Pandhare A, Blanton MP. (±)-2-(N-tert-Butylamino)-3'-[(125)I]-iodo-4'-azidopropiophenone: a dopamine transporter and nicotinic acetylcholine receptor photoaffinity ligand based on bupropion (Wellbutrin, Zyban). Bioorganic & Medicinal Chemistry Letters. 22: 523-6. PMID 22119468 DOI: 10.1016/j.bmcl.2011.10.086  1
2011 Speed N, Saunders C, Davis AR, Owens WA, Matthies HJ, Saadat S, Kennedy JP, Vaughan RA, Neve RL, Lindsley CW, Russo SJ, Daws LC, Niswender KD, Galli A. Impaired striatal Akt signaling disrupts dopamine homeostasis and increases feeding. Plos One. 6: e25169. PMID 21969871 DOI: 10.1371/journal.pone.0025169  1
2011 Lapinsky DJ, Velagaleti R, Yarravarapu N, Liu Y, Huang Y, Surratt CK, Lever JR, Foster JD, Acharya R, Vaughan RA, Deutsch HM. Azido-iodo-N-benzyl derivatives of threo-methylphenidate (Ritalin, Concerta): Rational design, synthesis, pharmacological evaluation, and dopamine transporter photoaffinity labeling. Bioorganic & Medicinal Chemistry. 19: 504-12. PMID 21129986 DOI: 10.1016/j.bmc.2010.11.002  1
2011 Foster JD, Vaughan RA. Palmitoylation controls dopamine transporter kinetics, degradation, and protein kinase C-dependent regulation. The Journal of Biological Chemistry. 286: 5175-86. PMID 21118819 DOI: 10.1074/jbc.M110.187872  0.72
2011 Vaughan R. NET, norepinephrine transporter Xpharm: the Comprehensive Pharmacology Reference. 1-11. DOI: 10.1016/B978-008055232-3.60443-X  1
2011 Parnas ML, Vaughan R. DAT, dopamine transporter Xpharm: the Comprehensive Pharmacology Reference. 1-10. DOI: 10.1016/B978-008055232-3.60441-6  1
2010 Speed NK, Matthies HJ, Kennedy JP, Vaughan RA, Javitch JA, Russo SJ, Lindsley CW, Niswender K, Galli A. Akt-dependent and isoform-specific regulation of dopamine transporter cell surface expression. Acs Chemical Neuroscience. 1: 476-81. PMID 22778840 DOI: 10.1021/cn100031t  1
2010 Cervinski MA, Foster JD, Vaughan RA. Syntaxin 1A regulates dopamine transporter activity, phosphorylation and surface expression. Neuroscience. 170: 408-16. PMID 20643191 DOI: 10.1016/j.neuroscience.2010.07.025  1
2009 Lapinsky DJ, Aggarwal S, Huang Y, Surratt CK, Lever JR, Foster JD, Vaughan RA. A novel photoaffinity ligand for the dopamine transporter based on pyrovalerone. Bioorganic & Medicinal Chemistry. 17: 3770-4. PMID 19442525 DOI: 10.1016/j.bmc.2009.04.057  1
2009 Gorentla BK, Moritz AE, Foster JD, Vaughan RA. Proline-directed phosphorylation of the dopamine transporter N-terminal domain. Biochemistry. 48: 1067-76. PMID 19146407 DOI: 10.1021/bi801696n  1
2008 Foster JD, Adkins SD, Lever JR, Vaughan RA. Phorbol ester induced trafficking-independent regulation and enhanced phosphorylation of the dopamine transporter associated with membrane rafts and cholesterol. Journal of Neurochemistry. 105: 1683-99. PMID 18248623 DOI: 10.1111/j.1471-4159.2008.05262.x  0.72
2008 Parnas ML, Gaffaney JD, Zou MF, Lever JR, Newman AH, Vaughan RA. Labeling of dopamine transporter transmembrane domain 1 with the tropane ligand N-[4-(4-azido-3-[125I]iodophenyl)butyl]-2beta-carbomethoxy-3beta-(4-chlorophenyl)tropane implicates proximity of cocaine and substrate active sites. Molecular Pharmacology. 73: 1141-50. PMID 18216182 DOI: 10.1124/mol.107.043679  1
2007 Vaughan RA, Sakrikar DS, Parnas ML, Adkins S, Foster JD, Duval RA, Lever JR, Kulkarni SS, Hauck-Newman A. Localization of cocaine analog [125I]RTI 82 irreversible binding to transmembrane domain 6 of the dopamine transporter. The Journal of Biological Chemistry. 282: 8915-25. PMID 17255098 DOI: 10.1074/jbc.M610633200  1
2006 Newman AH, Cha JH, Cao J, Kopajtic T, Katz JL, Parnas ML, Vaughan R, Lever JR. Design and synthesis of a novel photoaffinity ligand for the dopamine and serotonin transporters based on 2beta-carbomethoxy-3beta-biphenyltropane. Journal of Medicinal Chemistry. 49: 6621-5. PMID 17064081 DOI: 10.1021/jm0603973  1
2006 Foster JD, Cervinski MA, Gorentla BK, Vaughan RA. Regulation of the dopamine transporter by phosphorylation. Handbook of Experimental Pharmacology. 197-214. PMID 16722237 DOI: 10.1007/3-540-29784-7-10  1
2006 Henry LK, Field JR, Adkins EM, Parnas ML, Vaughan RA, Zou MF, Newman AH, Blakely RD. Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants. The Journal of Biological Chemistry. 281: 2012-23. PMID 16272152 DOI: 10.1074/jbc.M505055200  1
2005 Cervinski MA, Foster JD, Vaughan RA. Psychoactive substrates stimulate dopamine transporter phosphorylation and down-regulation by cocaine-sensitive and protein kinase C-dependent mechanisms. The Journal of Biological Chemistry. 280: 40442-9. PMID 16204245 DOI: 10.1074/jbc.M501969200  1
2005 Gorentla BK, Vaughan RA. Differential effects of dopamine and psychoactive drugs on dopamine transporter phosphorylation and regulation. Neuropharmacology. 49: 759-68. PMID 16181646 DOI: 10.1016/j.neuropharm.2005.08.011  1
2005 Lever JR, Zou MF, Parnas ML, Duval RA, Wirtz SE, Justice JB, Vaughan RA, Newman AH. Radioiodinated azide and isothiocyanate derivatives of cocaine for irreversible labeling of dopamine transporters: synthesis and covalent binding studies. Bioconjugate Chemistry. 16: 644-9. PMID 15898733 DOI: 10.1021/bc0497214  1
2005 Vaughan RA, Parnas ML, Gaffaney JD, Lowe MJ, Wirtz S, Pham A, Reed B, Dutta SM, Murray KK, Justice JB. Affinity labeling the dopamine transporter ligand binding site. Journal of Neuroscience Methods. 143: 33-40. PMID 15763134 DOI: 10.1016/j.jneumeth.2004.09.022  1
2004 Gaffaney JD, Vaughan RA. Uptake inhibitors but not substrates induce protease resistance in extracellular loop two of the dopamine transporter. Molecular Pharmacology. 65: 692-701. PMID 14978248 DOI: 10.1124/mol.65.3.692  1
2003 Foster JD, Pananusorn B, Cervinski MA, Holden HE, Vaughan RA. Dopamine transporters are dephosphorylated in striatal homogenates and in vitro by protein phosphatase 1. Brain Research. Molecular Brain Research. 110: 100-8. PMID 12573538 DOI: 10.1016/S0169-328X(02)00645-9  1
2002 Foster JD, Pananusorn B, Vaughan RA. Dopamine transporters are phosphorylated on N-terminal serines in rat striatum. The Journal of Biological Chemistry. 277: 25178-86. PMID 11994276 DOI: 10.1074/jbc.M200294200  0.72
2001 Vaughan RA, Gaffaney JD, Lever JR, Reith ME, Dutta AK. Dual incorporation of photoaffinity ligands on dopamine transporters implicates proximity of labeled domains. Molecular Pharmacology. 59: 1157-64. PMID 11306699 DOI: 10.1124/mol.59.5.1157  1
2001 Dutta AK, Fei XS, Vaughan RA, Gaffaney JD, Wang N, Lever JR, Reith ME. Design, synthesis, and characterization of a novel, 4-[2-(diphenylmethoxy)ethyl]-1-benzyl piperidine-based, dopamine transporter photoaffinity label. Life Sciences. 68: 1839-49. PMID 11292062 DOI: 10.1016/S0024-3205(01)00981-X  1
2000 Thompson AC, Zapata A, Justice JB, Vaughan RA, Sharpe LG, Shippenberg TS. Kappa-opioid receptor activation modifies dopamine uptake in the nucleus accumbens and opposes the effects of cocaine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 9333-40. PMID 11125013  1
2000 Bauman AL, Apparsundaram S, Ramamoorthy S, Wadzinski BE, Vaughan RA, Blakely RD. Cocaine and antidepressant-sensitive biogenic amine transporters exist in regulated complexes with protein phosphatase 2A. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7571-8. PMID 11027216  1
1999 Letchworth SR, Sexton T, Childers SR, Vrana KE, Vaughan RA, Davies HM, Porrino LJ. Regulation of rat dopamine transporter mRNA and protein by chronic cocaine administration. Journal of Neurochemistry. 73: 1982-9. PMID 10537056  1
1999 Garzón M, Vaughan RA, Uhl GR, Kuhar MJ, Pickel VM. Cholinergic axon terminals in the ventral tegmental area target a subpopulation of neurons expressing low levels of the dopamine transporter. The Journal of Comparative Neurology. 410: 197-210. PMID 10414527 DOI: 10.1002/(SICI)1096-9861(19990726)410:2<197::AID-CNE3>3.0.CO;2-D  1
1998 Kokoshka JM, Vaughan RA, Hanson GR, Fleckenstein AE. Nature of methamphetamine-induced rapid and reversible changes in dopamine transporters European Journal of Pharmacology. 361: 269-275. PMID 9865517 DOI: 10.1016/S0014-2999(98)00741-9  1
1998 Vaughan RA. Cocaine and GBR photoaffinity labels as probes of dopamine transporter structure Methods in Enzymology. 296: 219-230. PMID 9779451 DOI: 10.1016/S0076-6879(98)96017-7  1
1998 Boja JW, Carroll FI, Vaughan RA, Kopajtic T, Kuhar MJ. Multiple binding sites for [125I]RTI-121 and other cocaine analogs in rat frontal cerebral cortex. Synapse (New York, N.Y.). 30: 9-17. PMID 9704876 DOI: 10.1002/(SICI)1098-2396(199809)30:1<9::AID-SYN2>3.0.CO;2-7  1
1998 Vaughan RA, Huff RA, Uhl GR, Kuhar MJ. Phosphorylation of dopamine transporters and rapid adaptation to cocaine. Advances in Pharmacology (San Diego, Calif.). 42: 1042-5. PMID 9328076 DOI: 10.1016/S1054-3589(08)60925-4  1
1997 Vaughan RA, Huff RA, Uhl GR, Kuhar MJ. Protein kinase C-mediated phosphorylation and functional regulation of dopamine transporters in striatal synaptosomes. The Journal of Biological Chemistry. 272: 15541-6. PMID 9182590 DOI: 10.1074/jbc.272.24.15541  1
1997 Huff RA, Vaughan RA, Kuhar MJ, Uhl GR. Phorbol esters increase dopamine transporter phosphorylation and decrease transport Vmax. Journal of Neurochemistry. 68: 225-32. PMID 8978729 DOI: 10.1046/j.1471-4159.1997.68010225.x  1
1996 Vaughan RA, Brown VL, McCoy MT, Kuhar MJ. Species- and brain region-specific dopamine transporters: immunological and glycosylation characteristics. Journal of Neurochemistry. 66: 2146-52. PMID 8780047 DOI: 10.1046/j.1471-4159.1996.66052146.x  1
1996 Vaughan RA, Kuhar MJ. Dopamine transporter ligand binding domains. Structural and functional properties revealed by limited proteolysis. The Journal of Biological Chemistry. 271: 21672-80. PMID 8702957 DOI: 10.1074/jbc.271.35.21672  1
1995 Freed C, Revay R, Vaughan RA, Kriek E, Grant S, Uhl GR, Kuhar MJ. Dopamine transporter immunoreactivity in rat brain. The Journal of Comparative Neurology. 359: 340-9. PMID 7499533 DOI: 10.1002/cne.903590211  1
1991 Vaughan RA, Simantov R, Lew R, Kuhar MJ. A rapid binding assay for solubilized dopamine transporters using [3H]WIN 35,428. Journal of Neuroscience Methods. 40: 9-16. PMID 1795555 DOI: 10.1016/0165-0270(91)90112-D  1
Show low-probability matches.