Nancy Carrasco - Publications

Affiliations: 
Yeshiva University, New York, NY, United States 
Area:
Molecular Biology, Pharmacology, Biochemistry

72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Ravera S, Nicola JP, Salazar-De Simone G, Sigworth FJ, Karakas E, Amzel LM, Bianchet MA, Carrasco N. Structural insights into the mechanism of the sodium/iodide symporter. Nature. PMID 36517601 DOI: 10.1038/s41586-022-05530-2  0.796
2021 Martín M, Modenutti CP, Gil Rosas ML, Peyret V, Geysels RC, Bernal Barquero CE, Sobrero G, Muñoz L, Signorino M, Testa G, Miras MB, Masini-Repiso AM, Calcaterra NB, Coux G, Carrasco N, et al. A Novel SLC5A5 Variant Reveals the Crucial Role of Kinesin Light Chain 2 in Thyroid Hormonogenesis. The Journal of Clinical Endocrinology and Metabolism. PMID 33912899 DOI: 10.1210/clinem/dgab283  0.439
2021 Reyna-Neyra A, Jung L, Chakrabarti M, Suarez M, Amzel LM, Carrasco N. The iodide transport defect-causing Y348D mutation in the Na/I symporter (NIS) renders the protein intrinsically inactive and impairs its targeting to the plasma membrane. Thyroid : Official Journal of the American Thyroid Association. PMID 33779310 DOI: 10.1089/thy.2020.0931  0.527
2020 Llorente-Esteban A, Manville RW, Reyna-Neyra A, Abbott GW, Amzel LM, Carrasco N. Allosteric regulation of mammalian Na/I symporter activity by perchlorate. Nature Structural & Molecular Biology. 27: 533-539. PMID 32451489 DOI: 10.1038/S41594-020-0417-5  0.5
2020 Carrasco N. Molecular architecture of the key precursor of thyroid hormones revealed. Nature. 578: 520-521. PMID 32094915 DOI: 10.1038/D41586-020-00244-9  0.419
2019 Martín M, Modenutti CP, Peyret V, Geysels RC, Darrouzet E, Pourcher T, Masini-Repiso AM, Martí MA, Carrasco N, Nicola JP. A Carboxy-Terminal Monoleucine-Based Motif Participates in the Basolateral Targeting of the Na+/I- Symporter. Endocrinology. 160: 156-168. PMID 30496374 DOI: 10.1210/En.2018-00603  0.64
2019 Ravera S, Nicola JP, Mu X, Echeverría I, Sanchez YE, Amzel LM, Carrasco N. On the Nature of the High-Affinity Iodide Binding Site of the Na+/I− Symporter (NIS) Biophysical Journal. 116: 169a. DOI: 10.1016/J.Bpj.2018.11.939  0.412
2019 Llorente Esteban A, Reyna-Neyra A, Manville RW, Abbott GW, Carrasco N, Amzel LM. Perchlorate Binding to a Cryptic Allosteric Site Changes the Mechanism of Iodide Transport by the Na+/I− Symporter (NIS) Biophysical Journal. 116: 553a. DOI: 10.1016/J.Bpj.2018.11.2976  0.503
2018 Ravera S, Carrasco N, Gelernter J, Polimanti R. Phenomic Impact of Genetically-Determined Euthyroid Function and Molecular Differences between Thyroid Disorders. Journal of Clinical Medicine. 7. PMID 30248900 DOI: 10.3390/Jcm7100296  0.372
2018 Ziros PG, Habeos I, Chartoumpekis DV, Ntalampyra E, Somm E, Renaud CO, Bongiovanni M, Trougakos IP, Yamamoto M, Kensler TW, Santisteban P, Carrasco N, Ris-Stalpers C, Amendola E, Liao XH, et al. The NFE2-related transcription factor 2 (Nrf2) coordinates antioxidant defense with thyroglobulin production and iodination in the thyroid gland. Thyroid : Official Journal of the American Thyroid Association. PMID 29742982 DOI: 10.1089/Thy.2018.0018  0.339
2017 Ferrandino G, Kaspari RR, Reyna-Neyra A, Boutagy NE, Sinusas AJ, Carrasco N. An extremely high dietary iodide supply forestalls severe hypothyroidism in Na(+)/I(-) symporter (NIS) knockout mice. Scientific Reports. 7: 5329. PMID 28706256 DOI: 10.1038/S41598-017-04326-Z  0.539
2017 Ravera S, Reyna-Neyra A, Ferrandino G, Amzel LM, Carrasco N. The Sodium/Iodide Symporter (NIS): Molecular Physiology and Preclinical and Clinical Applications. Annual Review of Physiology. 79: 261-289. PMID 28192058 DOI: 10.1146/Annurev-Physiol-022516-034125  0.644
2016 Nagarajah J, Le M, Knauf JA, Ferrandino G, Montero-Conde C, Pillarsetty N, Bolaender A, Irwin C, Krishnamoorthy GP, Saqcena M, Larson SM, Ho AL, Seshan V, Ishii N, Carrasco N, et al. Sustained ERK inhibition maximizes responses of BrafV600E thyroid cancers to radioiodine. The Journal of Clinical Investigation. PMID 27669459 DOI: 10.1172/Jci89067  0.47
2016 Ferrandino G, Nicola JP, Sánchez YE, Echeverria I, Liu Y, Amzel LM, Carrasco N. Na+ coordination at the Na2 site of the Na+/I- symporter. Proceedings of the National Academy of Sciences of the United States of America. PMID 27562170 DOI: 10.1073/Pnas.1607231113  0.589
2016 Renier C, Do J, Reyna-Neyra A, Foster D, De A, Vogel H, Jeffrey SS, Tse V, Carrasco N, Wapnir I. Regression of experimental NIS-expressing breast cancer brain metastases in response to radioiodide/gemcitabine dual therapy. Oncotarget. PMID 27363025 DOI: 10.18632/Oncotarget.10238  0.357
2015 Nicola JP, Reyna-Neyra A, Saenger P, Rodriguez-Buritica DF, Gamez Godoy JD, Muzumdar R, Amzel LM, Carrasco N. Sodium/Iodide Symporter Mutant V270E Causes Stunted Growth but No Cognitive Deficiency. The Journal of Clinical Endocrinology and Metabolism. 100: E1353-61. PMID 26204134 DOI: 10.1210/Jc.2015-1824  0.612
2015 Ravera S, Quick M, Nicola JP, Carrasco N, Amzel LM. Beyond non-integer Hill coefficients: A novel approach to analyzing binding data, applied to Na+-driven transporters. The Journal of General Physiology. 145: 555-63. PMID 26009546 DOI: 10.1085/Jgp.201511365  0.523
2015 Nicola JP, Carrasco N, Masini-Repiso AM. Dietary I(-) absorption: expression and regulation of the Na(+)/I(-) symporter in the intestine. Vitamins and Hormones. 98: 1-31. PMID 25817864 DOI: 10.1016/Bs.Vh.2014.12.002  0.64
2015 Arriagada AA, Albornoz E, Opazo MC, Becerra A, Vidal G, Fardella C, Michea L, Carrasco N, Simon F, Elorza AA, Bueno SM, Kalergis AM, Riedel CA. Excess iodide induces an acute inhibition of the sodium/iodide symporter in thyroid male rat cells by increasing reactive oxygen species. Endocrinology. 156: 1540-51. PMID 25594695 DOI: 10.1210/En.2014-1371  0.724
2015 Sanchez YE, Amzel LM, Carrasco N, Nicola JP, Ferrandino G. Effect of Mutations on Transport by the Sodium/Iodide Symporter (NIS) Biophysical Journal. 108: 309a. DOI: 10.1016/J.Bpj.2014.11.1678  0.593
2015 Ravera S, Quick M, Nicola JP, Carrasco N, Amzel ML. A Novel Approach to Analyzing Binding Data from Na+ Driven Transporters: Beyond Non-Integer Hill Coefficients Biophysical Journal. 108: 308a. DOI: 10.1016/J.Bpj.2014.11.1675  0.473
2014 Nicola JP, Carrasco N, Amzel LM. Physiological sodium concentrations enhance the iodide affinity of the Na+/I- symporter. Nature Communications. 5: 3948. PMID 24888603 DOI: 10.1038/Ncomms4948  0.599
2014 Portulano C, Paroder-Belenitsky M, Carrasco N. The Na+/I- symporter (NIS): mechanism and medical impact. Endocrine Reviews. 35: 106-49. PMID 24311738 DOI: 10.1210/Er.2012-1036  0.848
2013 Paroder V, Nicola JP, Ginter CS, Carrasco N. The iodide-transport-defect-causing mutation R124H: a δ-amino group at position 124 is critical for maturation and trafficking of the Na+/I- symporter. Journal of Cell Science. 126: 3305-13. PMID 23690546 DOI: 10.1242/Jcs.120246  0.784
2013 Li W, Nicola JP, Amzel LM, Carrasco N. Asn441 plays a key role in folding and function of the Na+/I- symporter (NIS). Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 3229-38. PMID 23650190 DOI: 10.1096/Fj.13-229138  0.669
2012 Nicola JP, Reyna-Neyra A, Carrasco N, Masini-Repiso AM. Dietary iodide controls its own absorption through post-transcriptional regulation of the intestinal Na+/I- symporter. The Journal of Physiology. 590: 6013-26. PMID 23006481 DOI: 10.1113/Jphysiol.2012.241307  0.571
2012 Lacoste C, Hervé J, Bou Nader M, Dos Santos A, Moniaux N, Valogne Y, Montjean R, Dorseuil O, Samuel D, Cassio D, Portulano C, Carrasco N, Bréchot C, Faivre J. Iodide transporter NIS regulates cancer cell motility and invasiveness by interacting with the Rho guanine nucleotide exchange factor LARG. Cancer Research. 72: 5505-15. PMID 22962269 DOI: 10.1158/0008-5472.Can-12-0516  0.801
2012 Purtell K, Paroder-Belenitsky M, Reyna-Neyra A, Nicola JP, Koba W, Fine E, Carrasco N, Abbott GW. The KCNQ1-KCNE2 K⁺ channel is required for adequate thyroid I⁻ uptake. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 3252-9. PMID 22549510 DOI: 10.1096/Fj.12-206110  0.518
2011 Paroder-Belenitsky M, Maestas MJ, Dohán O, Nicola JP, Reyna-Neyra A, Follenzi A, Dadachova E, Eskandari S, Amzel LM, Carrasco N. Mechanism of anion selectivity and stoichiometry of the Na+/I- symporter (NIS). Proceedings of the National Academy of Sciences of the United States of America. 108: 17933-8. PMID 22011571 DOI: 10.1073/Pnas.1108278108  0.667
2010 Kakizaki F, Aoki K, Miyoshi H, Carrasco N, Aoki M, Taketo MM. CDX transcription factors positively regulate expression of solute carrier family 5, member 8 in the colonic epithelium. Gastroenterology. 138: 627-35. PMID 19900445 DOI: 10.1053/J.Gastro.2009.10.047  0.316
2010 Carrasco N. Single Amino Acid Substitutions Change the Sodium/Iodide Symporter (NIS) Selectivity and Stoichiometry Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.302  0.694
2009 Riesco-Eizaguirre G, Rodríguez I, De la Vieja A, Costamagna E, Carrasco N, Nistal M, Santisteban P. The BRAFV600E oncogene induces transforming growth factor beta secretion leading to sodium iodide symporter repression and increased malignancy in thyroid cancer. Cancer Research. 69: 8317-25. PMID 19861538 DOI: 10.1158/0008-5472.Can-09-1248  0.448
2009 Roepke TK, King EC, Reyna-Neyra A, Paroder M, Purtell K, Koba W, Fine E, Lerner DJ, Carrasco N, Abbott GW. Kcne2 deletion uncovers its crucial role in thyroid hormone biosynthesis. Nature Medicine. 15: 1186-94. PMID 19767733 DOI: 10.1038/Nm.2029  0.382
2009 Nicola JP, Basquin C, Portulano C, Reyna-Neyra A, Paroder M, Carrasco N. The Na+/I- symporter mediates active iodide uptake in the intestine. American Journal of Physiology. Cell Physiology. 296: C654-62. PMID 19052257 DOI: 10.1152/Ajpcell.00509.2008  0.841
2008 Reed-Tsur MD, De la Vieja A, Ginter CS, Carrasco N. Molecular characterization of V59E NIS, a Na+/I- symporter mutant that causes congenital I- transport defect. Endocrinology. 149: 3077-84. PMID 18339708 DOI: 10.1210/En.2008-0027  0.714
2007 Dohán O, Portulano C, Basquin C, Reyna-Neyra A, Amzel LM, Carrasco N. The Na+/I symporter (NIS) mediates electroneutral active transport of the environmental pollutant perchlorate. Proceedings of the National Academy of Sciences of the United States of America. 104: 20250-5. PMID 18077370 DOI: 10.1073/Pnas.0707207104  0.842
2007 De la Vieja A, Reed MD, Ginter CS, Carrasco N. Amino acid residues in transmembrane segment IX of the Na+/I- symporter play a role in its Na+ dependence and are critical for transport activity. The Journal of Biological Chemistry. 282: 25290-8. PMID 17606623 DOI: 10.1074/Jbc.M700147200  0.625
2007 Altorjay A, Dohán O, Szilágyi A, Paroder M, Wapnir IL, Carrasco N. Expression of the Na+/I- symporter (NIS) is markedly decreased or absent in gastric cancer and intestinal metaplastic mucosa of Barrett esophagus. Bmc Cancer. 7: 5. PMID 17214887 DOI: 10.1186/1471-2407-7-5  0.605
2006 Paroder V, Spencer SR, Paroder M, Arango D, Schwartz S, Mariadason JM, Augenlicht LH, Eskandari S, Carrasco N. Na(+)/monocarboxylate transport (SMCT) protein expression correlates with survival in colon cancer: molecular characterization of SMCT. Proceedings of the National Academy of Sciences of the United States of America. 103: 7270-5. PMID 16670197 DOI: 10.1073/Pnas.0602365103  0.759
2006 Dohán O, De la Vieja A, Carrasco N. Hydrocortisone and purinergic signaling stimulate sodium/iodide symporter (NIS)-mediated iodide transport in breast cancer cells. Molecular Endocrinology (Baltimore, Md.). 20: 1121-37. PMID 16439463 DOI: 10.1210/Me.2005-0376  0.573
2005 De la Vieja A, Ginter CS, Carrasco N. Molecular analysis of a congenital iodide transport defect: G543E impairs maturation and trafficking of the Na+/I- symporter. Molecular Endocrinology (Baltimore, Md.). 19: 2847-58. PMID 15976004 DOI: 10.1210/Me.2005-0162  0.662
2004 Dohán O, Carrasco N. Thyroidal iodide transport and thyroid cancer. Cancer Treatment and Research. 122: 221-36. PMID 16209048 DOI: 10.1007/1-4020-8107-3_13  0.516
2004 Wapnir IL, Goris M, Yudd A, Dohan O, Adelman D, Nowels K, Carrasco N. The Na+/I- symporter mediates iodide uptake in breast cancer metastases and can be selectively down-regulated in the thyroid. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 4294-302. PMID 15240514 DOI: 10.1158/1078-0432.Ccr-04-0074  0.54
2004 Dadachova E, Carrasco N. The Na/I symporter (NIS): imaging and therapeutic applications. Seminars in Nuclear Medicine. 34: 23-31. PMID 14735456 DOI: 10.1053/J.Semnuclmed.2003.09.004  0.564
2004 De La Vieja A, Ginter CS, Carrasco N. The Q267E mutation in the sodium/iodide symporter (NIS) causes congenital iodide transport defect (ITD) by decreasing the NIS turnover number. Journal of Cell Science. 117: 677-87. PMID 14734652 DOI: 10.1242/Jcs.00898  0.635
2003 Dohán O, Carrasco N. Advances in Na(+)/I(-) symporter (NIS) research in the thyroid and beyond. Molecular and Cellular Endocrinology. 213: 59-70. PMID 15062574 DOI: 10.1016/J.Mce.2003.10.059  0.627
2003 Wapnir IL, van de Rijn M, Nowels K, Amenta PS, Walton K, Montgomery K, Greco RS, Dohán O, Carrasco N. Immunohistochemical profile of the sodium/iodide symporter in thyroid, breast, and other carcinomas using high density tissue microarrays and conventional sections. The Journal of Clinical Endocrinology and Metabolism. 88: 1880-8. PMID 12679487 DOI: 10.1210/Jc.2002-021544  0.468
2003 Dohán O, De la Vieja A, Paroder V, Riedel C, Artani M, Reed M, Ginter CS, Carrasco N. The sodium/iodide Symporter (NIS): characterization, regulation, and medical significance. Endocrine Reviews. 24: 48-77. PMID 12588808 DOI: 10.1210/Er.2001-0029  0.844
2002 Dohán O, Gavrielides MV, Ginter C, Amzel LM, Carrasco N. Na(+)/I(-) symporter activity requires a small and uncharged amino acid residue at position 395. Molecular Endocrinology (Baltimore, Md.). 16: 1893-902. PMID 12145342 DOI: 10.1210/Me.2002-0071  0.627
2002 Zhang X, Riedel C, Carrasco N, Arvan P. Polarized trafficking of thyrocyte proteins in MDCK cells. Molecular and Cellular Endocrinology. 188: 27-36. PMID 11911943 DOI: 10.1016/S0303-7207(01)00751-1  0.646
2001 Riedel C, Dohán O, De la Vieja A, Ginter CS, Carrasco N. Journey of the iodide transporter NIS: from its molecular identification to its clinical role in cancer. Trends in Biochemical Sciences. 26: 490-6. PMID 11504625 DOI: 10.1016/S0968-0004(01)01904-1  0.788
2001 Dohán O, Baloch Z, Bánrévi Z, Livolsi V, Carrasco N. Rapid communication: predominant intracellular overexpression of the Na(+)/I(-) symporter (NIS) in a large sampling of thyroid cancer cases. The Journal of Clinical Endocrinology and Metabolism. 86: 2697-700. PMID 11397873 DOI: 10.1210/Jcem.86.6.7746  0.613
2001 Riedel C, Levy O, Carrasco N. Post-transcriptional regulation of the sodium/iodide symporter by thyrotropin. The Journal of Biological Chemistry. 276: 21458-63. PMID 11290744 DOI: 10.1074/Jbc.M100561200  0.736
2001 Dohan O, De la Vieja A, Carrasco N. Molecular study of the sodium-iodide symporter (NIS): a new field in thyroidology. Trends in Endocrinology and Metabolism: Tem. 11: 99-105. PMID 10707050 DOI: 10.1016/S1043-2760(00)00237-X  0.641
2000 Tazebay UH, Wapnir IL, Levy O, Dohan O, Zuckier LS, Zhao QH, Deng HF, Amenta PS, Fineberg S, Pestell RG, Carrasco N. The mammary gland iodide transporter is expressed during lactation and in breast cancer. Nature Medicine. 6: 871-8. PMID 10932223 DOI: 10.1038/78630  0.443
2000 De La Vieja A, Dohan O, Levy O, Carrasco N. Molecular analysis of the sodium/iodide symporter: impact on thyroid and extrathyroid pathophysiology. Physiological Reviews. 80: 1083-105. PMID 10893432 DOI: 10.1152/Physrev.2000.80.3.1083  0.581
2000 Deleu S, Allory Y, Radulescu A, Pirson I, Carrasco N, Corvilain B, Salmon I, Franc B, Dumont JE, Van Sande J, Maenhaut C. Characterization of autonomous thyroid adenoma: metabolism, gene expression, and pathology. Thyroid : Official Journal of the American Thyroid Association. 10: 131-40. PMID 10718549 DOI: 10.1089/Thy.2000.10.131  0.342
2000 Caturegli P, Hejazi M, Suzuki K, Dohan O, Carrasco N, Kohn LD, Rose NR. Hypothyroidism in transgenic mice expressing IFN-gamma in the thyroid. Proceedings of the National Academy of Sciences of the United States of America. 97: 1719-24. PMID 10677524 DOI: 10.1073/Pnas.020522597  0.389
1999 Eng PH, Cardona GR, Fang SL, Previti M, Alex S, Carrasco N, Chin WW, Braverman LE. Escape from the acute Wolff-Chaikoff effect is associated with a decrease in thyroid sodium/iodide symporter messenger ribonucleic acid and protein. Endocrinology. 140: 3404-10. PMID 10433193 DOI: 10.1210/Endo.140.8.6893  0.451
1999 Ohno M, Zannini M, Levy O, Carrasco N, di Lauro R. The paired-domain transcription factor Pax8 binds to the upstream enhancer of the rat sodium/iodide symporter gene and participates in both thyroid-specific and cyclic-AMP-dependent transcription. Molecular and Cellular Biology. 19: 2051-60. PMID 10022892 DOI: 10.1128/Mcb.19.3.2051  0.488
1998 Levy O, De la Vieja A, Ginter CS, Riedel C, Dai G, Carrasco N. N-linked glycosylation of the thyroid Na+/I- symporter (NIS). Implications for its secondary structure model. The Journal of Biological Chemistry. 273: 22657-63. PMID 9712895 DOI: 10.1074/Jbc.273.35.22657  0.728
1998 Levy O, De la Vieja A, Carrasco N. The Na+/I- symporter (NIS): recent advances. Journal of Bioenergetics and Biomembranes. 30: 195-206. PMID 9672241 DOI: 10.1023/A:1020577426732  0.646
1998 Levy O, Ginter CS, De la Vieja A, Levy D, Carrasco N. Identification of a structural requirement for thyroid Na+/I- symporter (NIS) function from analysis of a mutation that causes human congenital hypothyroidism. Febs Letters. 429: 36-40. PMID 9657379 DOI: 10.1016/S0014-5793(98)00522-5  0.617
1997 Eskandari S, Loo DD, Dai G, Levy O, Wright EM, Carrasco N. Thyroid Na+/I- symporter. Mechanism, stoichiometry, and specificity. The Journal of Biological Chemistry. 272: 27230-8. PMID 9341168 DOI: 10.1074/Jbc.272.43.27230  0.566
1997 Uyttersprot N, Pelgrims N, Carrasco N, Gervy C, Maenhaut C, Dumont JE, Miot F. Moderate doses of iodide in vivo inhibit cell proliferation and the expression of thyroperoxidase and Na+/I- symporter mRNAs in dog thyroid. Molecular and Cellular Endocrinology. 131: 195-203. PMID 9296378 DOI: 10.1016/S0303-7207(97)00108-1  0.47
1997 Levy O, Dai G, Riedel C, Ginter CS, Paul EM, Lebowitz AN, Carrasco N. Characterization of the thyroid Na+/I- symporter with an anti-COOH terminus antibody. Proceedings of the National Academy of Sciences of the United States of America. 94: 5568-73. PMID 9159113 DOI: 10.1073/Pnas.94.11.5568  0.749
1997 Levy O, Carrasco N. Structure and function of the thyroid iodide transporter and its implications for thyroid disease Current Opinion in Endocrinology and Diabetes. 4: 364-370. DOI: 10.1097/00060793-199710000-00008  0.505
1996 Dai G, Levy O, Carrasco N. Cloning and characterization of the thyroid iodide transporter. Nature. 379: 458-60. PMID 8559252 DOI: 10.1038/379458A0  0.548
1996 Dai G, Levy O, Amzel LM, Carrasco N. Chapter 15 The mediator of thyroidal iodide accumulation: The sodium/iodide symporter Handbook of Biological Physics. 2: 343-368. DOI: 10.1016/S1383-8121(96)80056-X  0.346
1994 Kaminsky SM, Levy O, Salvador C, Dai G, Carrasco N. Na(+)-I- symport activity is present in membrane vesicles from thyrotropin-deprived non-I(-)-transporting cultured thyroid cells. Proceedings of the National Academy of Sciences of the United States of America. 91: 3789-93. PMID 8170988 DOI: 10.1073/Pnas.91.9.3789  0.522
1993 Carrasco N. Iodide transport in the thyroid gland. Biochimica Et Biophysica Acta. 1154: 65-82. PMID 8507647 DOI: 10.1016/0304-4157(93)90017-I  0.521
1991 Kaminsky SM, Levy O, Garry MT, Carrasco N. Inhibition of the Na+/I- symporter by harmaline and 3-amino-1-methyl-5H-pyrido(4,3-b)indole acetate in thyroid cells and membrane vesicles. European Journal of Biochemistry. 200: 203-7. PMID 1879425 DOI: 10.1111/J.1432-1033.1991.Tb21068.X  0.452
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