Nancy Carrasco - Publications

Yeshiva University, New York, NY, United States 
Molecular Biology, Pharmacology, Biochemistry

35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Martín M, Modenutti CP, Peyret V, Geysels RC, Darrouzet E, Pourcher T, Masini-Repiso AM, Martí MA, Carrasco N, Nicola JP. A Carboxy-Terminal Monoleucine-Based Motif Participates in the Basolateral Targeting of the Na+/I- Symporter. Endocrinology. 160: 156-168. PMID 30496374 DOI: 10.1210/en.2018-00603  0.44
2017 Ferrandino G, Kaspari RR, Spadaro O, Reyna-Neyra A, Perry RJ, Cardone R, Kibbey RG, Shulman GI, Dixit VD, Carrasco N. Pathogenesis of hypothyroidism-induced NAFLD is driven by intra- and extrahepatic mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 114: E9172-E9180. PMID 29073114 DOI: 10.1073/pnas.1707797114  0.36
2017 Ferrandino G, Kaspari RR, Reyna-Neyra A, Boutagy NE, Sinusas AJ, Carrasco N. An extremely high dietary iodide supply forestalls severe hypothyroidism in Na(+)/I(-) symporter (NIS) knockout mice. Scientific Reports. 7: 5329. PMID 28706256 DOI: 10.1038/s41598-017-04326-z  0.36
2017 Ravera S, Reyna-Neyra A, Ferrandino G, Amzel LM, Carrasco N. The Sodium/Iodide Symporter (NIS): Molecular Physiology and Preclinical and Clinical Applications. Annual Review of Physiology. 79: 261-289. PMID 28192058 DOI: 10.1146/annurev-physiol-022516-034125  0.36
2016 Ferrandino G, Nicola JP, Sánchez YE, Echeverria I, Liu Y, Amzel LM, Carrasco N. Na+ coordination at the Na2 site of the Na+/I- symporter. Proceedings of the National Academy of Sciences of the United States of America. PMID 27562170 DOI: 10.1073/pnas.1607231113  0.44
2016 Renier C, Do J, Reyna-Neyra A, Foster D, De A, Vogel H, Jeffrey SS, Tse V, Carrasco N, Wapnir I. Regression of experimental NIS-expressing breast cancer brain metastases in response to radioiodide/gemcitabine dual therapy. Oncotarget. PMID 27363025 DOI: 10.18632/oncotarget.10238  0.36
2015 Oikawa T, Wauthier E, Dinh TA, Selitsky SR, Reyna-Neyra A, Carpino G, Levine R, Cardinale V, Klimstra D, Gaudio E, Alvaro D, Carrasco N, Sethupathy P, Reid LM. Model of fibrolamellar hepatocellular carcinomas reveals striking enrichment in cancer stem cells. Nature Communications. 6: 8070. PMID 26437858 DOI: 10.1038/ncomms9070  0.36
2015 Nicola JP, Reyna-Neyra A, Saenger P, Rodriguez-Buritica DF, Gamez Godoy JD, Muzumdar R, Amzel LM, Carrasco N. Sodium/Iodide Symporter Mutant V270E Causes Stunted Growth but No Cognitive Deficiency. The Journal of Clinical Endocrinology and Metabolism. 100: E1353-61. PMID 26204134 DOI: 10.1210/jc.2015-1824  0.36
2015 Ravera S, Quick M, Nicola JP, Carrasco N, Amzel LM. Beyond non-integer Hill coefficients: A novel approach to analyzing binding data, applied to Na+-driven transporters. The Journal of General Physiology. 145: 555-63. PMID 26009546 DOI: 10.1085/jgp.201511365  0.44
2015 Nicola JP, Carrasco N, Masini-Repiso AM. Dietary I(-) absorption: expression and regulation of the Na(+)/I(-) symporter in the intestine. Vitamins and Hormones. 98: 1-31. PMID 25817864 DOI: 10.1016/bs.vh.2014.12.002  0.44
2015 Arriagada AA, Albornoz E, Opazo MC, Becerra A, Vidal G, Fardella C, Michea L, Carrasco N, Simon F, Elorza AA, Bueno SM, Kalergis AM, Riedel CA. Excess iodide induces an acute inhibition of the sodium/iodide symporter in thyroid male rat cells by increasing reactive oxygen species. Endocrinology. 156: 1540-51. PMID 25594695 DOI: 10.1210/en.2014-1371  0.36
2014 Nicola JP, Carrasco N, Amzel LM. Physiological sodium concentrations enhance the iodide affinity of the Na+/I- symporter. Nature Communications. 5: 3948. PMID 24888603 DOI: 10.1038/ncomms4948  0.44
2014 Portulano C, Paroder-Belenitsky M, Carrasco N. The Na+/I- symporter (NIS): mechanism and medical impact. Endocrine Reviews. 35: 106-49. PMID 24311738 DOI: 10.1210/er.2012-1036  0.44
2013 Paroder V, Nicola JP, Ginter CS, Carrasco N. The iodide-transport-defect-causing mutation R124H: a δ-amino group at position 124 is critical for maturation and trafficking of the Na+/I- symporter. Journal of Cell Science. 126: 3305-13. PMID 23690546 DOI: 10.1242/jcs.120246  0.64
2013 Li W, Nicola JP, Amzel LM, Carrasco N. Asn441 plays a key role in folding and function of the Na+/I- symporter (NIS). Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 3229-38. PMID 23650190 DOI: 10.1096/fj.13-229138  0.36
2012 Nicola JP, Reyna-Neyra A, Carrasco N, Masini-Repiso AM. Dietary iodide controls its own absorption through post-transcriptional regulation of the intestinal Na+/I- symporter. The Journal of Physiology. 590: 6013-26. PMID 23006481 DOI: 10.1113/jphysiol.2012.241307  0.44
2012 Lacoste C, Hervé J, Bou Nader M, Dos Santos A, Moniaux N, Valogne Y, Montjean R, Dorseuil O, Samuel D, Cassio D, Portulano C, Carrasco N, Bréchot C, Faivre J. Iodide transporter NIS regulates cancer cell motility and invasiveness by interacting with the Rho guanine nucleotide exchange factor LARG. Cancer Research. 72: 5505-15. PMID 22962269 DOI: 10.1158/0008-5472.CAN-12-0516  0.44
2012 Purtell K, Paroder-Belenitsky M, Reyna-Neyra A, Nicola JP, Koba W, Fine E, Carrasco N, Abbott GW. The KCNQ1-KCNE2 K⁺ channel is required for adequate thyroid I⁻ uptake. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 3252-9. PMID 22549510 DOI: 10.1096/fj.12-206110  0.44
2011 Paroder-Belenitsky M, Maestas MJ, Dohán O, Nicola JP, Reyna-Neyra A, Follenzi A, Dadachova E, Eskandari S, Amzel LM, Carrasco N. Mechanism of anion selectivity and stoichiometry of the Na+/I- symporter (NIS). Proceedings of the National Academy of Sciences of the United States of America. 108: 17933-8. PMID 22011571 DOI: 10.1073/pnas.1108278108  0.36
2009 Riesco-Eizaguirre G, Rodríguez I, De la Vieja A, Costamagna E, Carrasco N, Nistal M, Santisteban P. The BRAFV600E oncogene induces transforming growth factor beta secretion leading to sodium iodide symporter repression and increased malignancy in thyroid cancer. Cancer Research. 69: 8317-25. PMID 19861538 DOI: 10.1158/0008-5472.CAN-09-1248  0.64
2009 Roepke TK, King EC, Reyna-Neyra A, Paroder M, Purtell K, Koba W, Fine E, Lerner DJ, Carrasco N, Abbott GW. Kcne2 deletion uncovers its crucial role in thyroid hormone biosynthesis. Nature Medicine. 15: 1186-94. PMID 19767733 DOI: 10.1038/nm.2029  0.36
2009 Nicola JP, Basquin C, Portulano C, Reyna-Neyra A, Paroder M, Carrasco N. The Na+/I- symporter mediates active iodide uptake in the intestine. American Journal of Physiology. Cell Physiology. 296: C654-62. PMID 19052257 DOI: 10.1152/ajpcell.00509.2008  0.44
2008 Reed-Tsur MD, De la Vieja A, Ginter CS, Carrasco N. Molecular characterization of V59E NIS, a Na+/I- symporter mutant that causes congenital I- transport defect. Endocrinology. 149: 3077-84. PMID 18339708 DOI: 10.1210/en.2008-0027  0.64
2007 Dohán O, Portulano C, Basquin C, Reyna-Neyra A, Amzel LM, Carrasco N. The Na+/I symporter (NIS) mediates electroneutral active transport of the environmental pollutant perchlorate. Proceedings of the National Academy of Sciences of the United States of America. 104: 20250-5. PMID 18077370 DOI: 10.1073/pnas.0707207104  0.36
2007 De la Vieja A, Reed MD, Ginter CS, Carrasco N. Amino acid residues in transmembrane segment IX of the Na+/I- symporter play a role in its Na+ dependence and are critical for transport activity. The Journal of Biological Chemistry. 282: 25290-8. PMID 17606623 DOI: 10.1074/jbc.M700147200  0.36
2007 Altorjay A, Dohán O, Szilágyi A, Paroder M, Wapnir IL, Carrasco N. Expression of the Na+/I- symporter (NIS) is markedly decreased or absent in gastric cancer and intestinal metaplastic mucosa of Barrett esophagus. Bmc Cancer. 7: 5. PMID 17214887 DOI: 10.1186/1471-2407-7-5  0.36
2006 Paroder V, Spencer SR, Paroder M, Arango D, Schwartz S, Mariadason JM, Augenlicht LH, Eskandari S, Carrasco N. Na(+)/monocarboxylate transport (SMCT) protein expression correlates with survival in colon cancer: molecular characterization of SMCT. Proceedings of the National Academy of Sciences of the United States of America. 103: 7270-5. PMID 16670197 DOI: 10.1073/pnas.0602365103  0.36
2006 Dohán O, De la Vieja A, Carrasco N. Hydrocortisone and purinergic signaling stimulate sodium/iodide symporter (NIS)-mediated iodide transport in breast cancer cells. Molecular Endocrinology (Baltimore, Md.). 20: 1121-37. PMID 16439463 DOI: 10.1210/me.2005-0376  0.64
2005 De la Vieja A, Ginter CS, Carrasco N. Molecular analysis of a congenital iodide transport defect: G543E impairs maturation and trafficking of the Na+/I- symporter. Molecular Endocrinology (Baltimore, Md.). 19: 2847-58. PMID 15976004 DOI: 10.1210/me.2005-0162  0.64
2004 Dohán O, Carrasco N. Thyroidal iodide transport and thyroid cancer. Cancer Treatment and Research. 122: 221-36. PMID 16209048  0.36
2004 Wapnir IL, Goris M, Yudd A, Dohan O, Adelman D, Nowels K, Carrasco N. The Na+/I- symporter mediates iodide uptake in breast cancer metastases and can be selectively down-regulated in the thyroid. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 4294-302. PMID 15240514 DOI: 10.1158/1078-0432.CCR-04-0074  0.36
2004 De La Vieja A, Ginter CS, Carrasco N. The Q267E mutation in the sodium/iodide symporter (NIS) causes congenital iodide transport defect (ITD) by decreasing the NIS turnover number. Journal of Cell Science. 117: 677-87. PMID 14734652 DOI: 10.1242/jcs.00898  0.64
2003 Dohán O, Carrasco N. Advances in Na(+)/I(-) symporter (NIS) research in the thyroid and beyond. Molecular and Cellular Endocrinology. 213: 59-70. PMID 15062574 DOI: 10.1016/j.mce.2003.10.059  0.36
2003 Dohán O, De la Vieja A, Paroder V, Riedel C, Artani M, Reed M, Ginter CS, Carrasco N. The sodium/iodide Symporter (NIS): characterization, regulation, and medical significance. Endocrine Reviews. 24: 48-77. PMID 12588808 DOI: 10.1210/er.2001-0029  0.64
2002 Dohán O, Gavrielides MV, Ginter C, Amzel LM, Carrasco N. Na(+)/I(-) symporter activity requires a small and uncharged amino acid residue at position 395. Molecular Endocrinology (Baltimore, Md.). 16: 1893-902. PMID 12145342 DOI: 10.1210/me.2002-0071  0.36
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