| Year |
Citation |
Score |
| 2017 |
Liyanage PS, Walker AR, Brenlla A, Cisneros GA, Romano LJ, Rueda D. Bulky Lesion Bypass Requires Dpo4 Binding in Distinct Conformations. Scientific Reports. 7: 17383. PMID 29234107 DOI: 10.1038/S41598-017-17643-0 |
0.727 |
|
| 2017 |
Gahlon H, Romano LJ, Rueda D. Influence of DNA Lesions on Polymerase-mediated DNA Replication at Single-Molecule Resolution. Chemical Research in Toxicology. PMID 29020440 DOI: 10.1021/Acs.Chemrestox.7B00224 |
0.699 |
|
| 2015 |
Brenlla A, Rueda D, Romano LJ. Mechanism of aromatic amine carcinogen bypass by the Y-family polymerase, Dpo4. Nucleic Acids Research. PMID 26481355 DOI: 10.1093/Nar/Gkv1067 |
0.752 |
|
| 2014 |
Brenlla A, Markiewicz RP, Rueda D, Romano LJ. Nucleotide selection by the Y-family DNA polymerase Dpo4 involves template translocation and misalignment. Nucleic Acids Research. 42: 2555-63. PMID 24270793 DOI: 10.1093/Nar/Gkt1149 |
0.671 |
|
| 2013 |
Vrtis KB, Markiewicz RP, Romano LJ, Rueda D. Carcinogenic adducts induce distinct DNA polymerase binding orientations. Nucleic Acids Research. 41: 7843-53. PMID 23814187 DOI: 10.1093/Nar/Gkt554 |
0.743 |
|
| 2013 |
Vrtis KB, Markiewicz R, Romano LJ, Rueda D. Unveiling DNA Polymerase Synthesis, Proofreading, and Mutagenesis Activities - One Molecule at a Time Biophysical Journal. 104: 176a. DOI: 10.1016/J.Bpj.2012.11.993 |
0.737 |
|
| 2012 |
Markiewicz RP, Vrtis KB, Rueda D, Romano LJ. Single-molecule microscopy reveals new insights into nucleotide selection by DNA polymerase I. Nucleic Acids Research. 40: 7975-84. PMID 22669904 DOI: 10.1093/Nar/Gks523 |
0.656 |
|
| 2010 |
Federley RG, Romano LJ. DNA polymerase: structural homology, conformational dynamics, and the effects of carcinogenic DNA adducts. Journal of Nucleic Acids. 2010. PMID 20847947 DOI: 10.4061/2010/457176 |
0.809 |
|
| 2009 |
Christian TD, Romano LJ, Rueda D. Single-molecule measurements of synthesis by DNA polymerase with base-pair resolution. Proceedings of the National Academy of Sciences of the United States of America. 106: 21109-14. PMID 19955412 DOI: 10.1073/Pnas.0908640106 |
0.841 |
|
| 2009 |
Christian TD, Romano LJ. Monitoring the conformation of benzo[a]pyrene adducts in the polymerase active site using fluorescence resonance energy transfer. Biochemistry. 48: 5382-8. PMID 19435285 DOI: 10.1021/Bi900148T |
0.835 |
|
| 2009 |
Vooradi V, Romano LJ. Effect of N-2-acetylaminofluorene and 2-aminofluorene adducts on DNA binding and synthesis by yeast DNA polymerase eta. Biochemistry. 48: 4209-16. PMID 19354292 DOI: 10.1021/Bi9000722 |
0.749 |
|
| 2007 |
Lone S, Romano LJ. The role of specific amino acid residues in the active site of Escherichia coli DNA polymerase I on translesion DNA synthesis across from and past an N-2-aminofluorene adduct. Biochemistry. 46: 2599-607. PMID 17305316 DOI: 10.1021/Bi061324O |
0.824 |
|
| 2005 |
Gill JP, Romano LJ. Mechanism for N-acetyl-2-aminofluorene-induced frameshift mutagenesis by Escherichia coli DNA polymerase I (Klenow fragment). Biochemistry. 44: 15387-95. PMID 16285743 DOI: 10.1021/Bi051437S |
0.831 |
|
| 2004 |
Dutta S, Li Y, Johnson D, Dzantiev L, Richardson CC, Romano LJ, Ellenberger T. Crystal structures of 2-acetylaminofluorene and 2-aminofluorene in complex with T7 DNA polymerase reveal mechanisms of mutagenesis. Proceedings of the National Academy of Sciences of the United States of America. 101: 16186-91. PMID 15528277 DOI: 10.1073/Pnas.0406516101 |
0.862 |
|
| 2003 |
Lone S, Romano LJ. Mechanistic insights into replication across from bulky DNA adducts: a mutant polymerase I allows an N-acetyl-2-aminofluorene adduct to be accommodated during DNA synthesis. Biochemistry. 42: 3826-34. PMID 12667073 DOI: 10.1021/Bi027297T |
0.787 |
|
| 2002 |
Alekseyev YO, Romano LJ. Effects of benzo[a]pyrene adduct stereochemistry on downstream DNA replication in vitro: evidence for different adduct conformations within the active site of DNA polymerase I (Klenow fragment). Biochemistry. 41: 4467-79. PMID 11914095 DOI: 10.1021/Bi015850L |
0.821 |
|
| 2001 |
Alekseyev YO, Dzantiev L, Romano LJ. Effects of benzo[a]pyrene DNA adducts on Escherichia coli DNA polymerase I (Klenow fragment) primer-template interactions: evidence for inhibition of the catalytically active ternary complex formation. Biochemistry. 40: 2282-90. PMID 11329298 DOI: 10.1021/Bi002245U |
0.84 |
|
| 2001 |
Dzantiev L, Alekseyev YO, Morales JC, Kool ET, Romano LJ. Significance of nucleobase shape complementarity and hydrogen bonding in the formation and stability of the closed polymerase - DNA complex Biochemistry. 40: 3215-3221. PMID 11258938 DOI: 10.1021/Bi002569I |
0.77 |
|
| 2000 |
Alekseyev YO, Romano LJ. In vitro replication of primer-templates containing benzo[a]pyrene adducts by exonuclease-deficient Escherichia coli DNA polymerase I (Klenow fragment): effect of sequence context on lesion bypass. Biochemistry. 39: 10431-8. PMID 10956033 DOI: 10.1021/Bi000552U |
0.783 |
|
| 2000 |
Dzantiev L, Romano LJ. Differential effects of N-acetyl-2-aminofluorene and N-2-aminofluorene adducts on the conformational change in the structure of DNA polymerase I (Klenow fragment). Biochemistry. 39: 5139-45. PMID 10819981 DOI: 10.1021/Bi992571D |
0.869 |
|
| 2000 |
Dzantiev L, Romano LJ. A conformational change in E. coli DNA polymerase I (Klenow fragment) is induced in the presence of a dNTP complementary to the template base in the active site. Biochemistry. 39: 356-61. PMID 10630996 DOI: 10.1021/Bi991952O |
0.865 |
|
| 1999 |
Weisenberger DJ, Romano LJ. Cytosine methylation in a CpG sequence leads to enhanced reactivity with Benzo[a]pyrene diol epoxide that correlates with a conformational change. The Journal of Biological Chemistry. 274: 23948-55. PMID 10446162 DOI: 10.1074/Jbc.274.34.23948 |
0.745 |
|
| 1999 |
Dzantiev L, Romano LJ. Interaction of Escherichia coli DNA polymerase I (Klenow fragment) with primer-templates containing N-acetyl-2-aminofluorene or N-2-aminofluorene adducts in the active site. The Journal of Biological Chemistry. 274: 3279-84. PMID 9920867 DOI: 10.1074/Jbc.274.6.3279 |
0.871 |
|
| 1998 |
Arghavani MB, SantaLucia J, Romano LJ. Effect of mismatched complementary strands and 5'-change in sequence context on the thermodynamics and structure of benzo[a]pyrene-modified oligonucleotides Biochemistry. 37: 8575-8583. PMID 9622509 DOI: 10.1021/Bi980237W |
0.552 |
|
| 1998 |
Mekhovich O, Tang Ms, Romano LJ. Rate of incision of N-acetyl-2-aminofluorene and N-2-aminofluorene adducts by UvrABC nuclease is adduct- and sequence-specific: comparison of the rates of UvrABC nuclease incision and protein-DNA complex formation. Biochemistry. 37: 571-9. PMID 9425079 DOI: 10.1021/Bi971544P |
0.645 |
|
| 1996 |
Yong Y, Romano LJ. Benzo[a]pyrene-DNA adducts inhibit the DNA helicase activity of the bacteriophage T7 gene 4 protein Chemical Research in Toxicology. 9: 179-187. PMID 8924589 DOI: 10.1021/Tx950112H |
0.614 |
|
| 1996 |
Arghavani MB, Romano LJ. A method for the purification of oligonucleotides containing strong intra- or intermolecular interactions by reversed-phase high-performance liquid chromatography. Analytical Biochemistry. 231: 201-9. PMID 8678302 DOI: 10.1006/Abio.1995.1521 |
0.307 |
|
| 1996 |
Li G, Wang H, Romano LJ. Human MutSα Specifically Binds to DNA Containing Aminofluorene and Acetylaminofluorene Adducts Journal of Biological Chemistry. 271: 24084-24088. DOI: 10.1074/Jbc.271.39.24084 |
0.649 |
|
| 1995 |
Rigler MN, Romano LJ. Differences in the mechanism of stimulation of T7 DNA polymerase by two binding modes of Escherichia coli single-stranded DNA-binding protein Journal of Biological Chemistry. 270: 8910-8919. PMID 7721799 DOI: 10.1074/Jbc.270.15.8910 |
0.659 |
|
| 1995 |
Yong Y, Romano LJ. Nucleotide and DNA-induced conformational changes in the bacteriophage T7 gene 4 protein Journal of Biological Chemistry. 270: 24509-24517. PMID 7592668 DOI: 10.1074/Jbc.270.41.24509 |
0.628 |
|
| 1994 |
Zhou Y, Romano LJ. Solid-phase synthesis of oligonucleotides containing site-specific N-(2'-deoxyguanosin-8-yl)-2-(acetylamino)fluorene adducts using 9-fluorenylmethoxycarbonyl as the base-protecting group. Biochemistry. 32: 14043-52. PMID 8268183 DOI: 10.1021/Bi00213A038 |
0.399 |
|
| 1994 |
Tebbs RS, Romano LJ. Mutagenesis at a site-specifically modified NarI sequence by acetylated and deacetylated aminofluorene adducts. Biochemistry. 33: 8998-9006. PMID 8043586 DOI: 10.1021/Bi00196A018 |
0.384 |
|
| 1994 |
Zhou Y, Chladek S, Romano LJ. Synthesis of Oligonucleotides Containing Site-specific Carcinogen Adducts. Preparation of the 2-Cyanoethyl N,N-Diisopropylphosphoramidite of N-(2'-Deoxyguanosin-8-yl)-2-(acetylamino)fluorene with Fmoc as the Base-Protecting Group The Journal of Organic Chemistry. 59: 556-563. DOI: 10.1021/Jo00082A011 |
0.371 |
|
| 1993 |
Levis RJ, Romano LJ, Rajan J, Schilke D, DeWitt M. High-speed DNA sequencing in the gas phase Proceedings of Spie. 1891: 102-112. DOI: 10.1117/12.146710 |
0.509 |
|
| 1991 |
Michaels ML, Reid TM, King CM, Romano LJ. Accurate in vitro translesion synthesis by Escherichia coli DNA polymerase I (large fragment) on a site-specific, aminofluorene-modified oligonucleotide. Carcinogenesis. 12: 1641-6. PMID 1893522 DOI: 10.1093/Carcin/12.9.1641 |
0.7 |
|
| 1991 |
Brown WC, Romano LJ. Effects of benzo[a]pyrene-DNA adducts on a reconstituted replication system. Biochemistry. 30: 1342-50. PMID 1846752 DOI: 10.1021/Bi00219A026 |
0.647 |
|
| 1991 |
Nath ST, Romano LJ. Transcription by T7 RNA polymerase using benzo[a]pyrene-modified templates Carcinogenesis. 12: 1531-1531. DOI: 10.1093/Carcin/12.8.1531-A |
0.507 |
|
| 1991 |
Romano LJ, Levis RJ. Nondestructive laser vaporization of high molecular weight, single-stranded DNA Journal of the American Chemical Society. 113: 9665-9667. DOI: 10.1021/Ja00025A038 |
0.502 |
|
| 1991 |
Levis RJ, Romano LJ. Laser vaporization of single-stranded DNA. A study of photoinduced phosphodiester bond scission Journal of the American Chemical Society. 113: 7802-7803. DOI: 10.1021/Ja00020A074 |
0.547 |
|
| 1989 |
Schaap AP, Akhavan H, Romano LJ. Chemiluminescent substrates for alkaline phosphatase: application to ultrasensitive enzyme-linked immunoassays and DNA probes. Clinical Chemistry. 35: 1863-1864. DOI: 10.1093/clinchem/35.9.1863 |
0.431 |
|
| 1987 |
Johnson DL, Reid TM, Lee MS, King CM, Romano LJ. Chemical stability of oligonucleotides containing the acetylated and deacetylated adducts of the carcinogen N-2-acetylaminofluorene. Carcinogenesis. 8: 619-23. PMID 3829325 DOI: 10.1093/Carcin/8.4.619 |
0.534 |
|
| 1987 |
Nath ST, Lee MS, Romano LJ. Effect of carcinogenic adducts on transcription by T7 RNA polymerase. Nucleic Acids Research. 15: 4257-71. PMID 3588293 DOI: 10.1093/Nar/15.10.4257 |
0.425 |
|
| 1986 |
Smeekens SP, Romano LJ. Promoter and nonspecific DNA binding by the T7 RNA polymerase. Nucleic Acids Research. 14: 2811-27. PMID 3960735 DOI: 10.1093/Nar/14.6.2811 |
0.554 |
|
| 1986 |
Johnson DL, Reid TM, Lee MS, King CM, Romano LJ. Preparation and characterization of a viral DNA molecule containing a site-specific 2-aminofluorene adduct: a new probe for mutagenesis by carcinogens. Biochemistry. 25: 449-56. PMID 3006762 DOI: 10.1021/Bi00350A026 |
0.673 |
|
| 1984 |
Basu AK, Marnett LJ, Romano LJ. Dissociation of malondialdehyde mutagenicity in Salmonella typhimurium from its ability to induce interstrand DNA cross-links. Mutation Research. 129: 39-46. PMID 6387469 DOI: 10.1016/0027-5107(84)90121-0 |
0.565 |
|
| 1981 |
Romano LJ, Tamanoi F, Richardson CC. Initiation of DNA replication at the primary origin of bacteriophage T7 by purified proteins: requirement for T7 RNA polymerase Proceedings of the National Academy of Sciences of the United States of America. 78: 4107-4111. PMID 6945573 DOI: 10.1073/Pnas.78.7.4107 |
0.624 |
|
| 1979 |
Richardson CC, Romano LJ, Kolodner R, LeClerc JE, Tamanoi F, Engler MJ, Dean FB, Richardson DS. Replication of bacteriophage T7 DNA by purified proteins. Cold Spring Harbor Symposia On Quantitative Biology. 427-40. PMID 225112 DOI: 10.1101/Sqb.1979.043.01.049 |
0.461 |
|
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