Michael R. Blackburn - Publications

Affiliations: 
The University of Texas Graduate School of Biomedical Sciences at Houston 
Area:
Pathology, Biochemistry

111 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Collum SD, Molina JG, Hanmandlu A, Bi W, Pedroza M, Mertens TCJ, Wareing N, Wei W, Wilson C, Sun W, Rajadas J, Bollyky PL, Philip KM, Ren D, Thandavarayan RA, ... ... Blackburn MR, et al. Adenosine and hyaluronan modulate lung fibrosis and pulmonary hypertension in combined pulmonary fibrosis and emphysema (CPFE). Disease Models & Mechanisms. PMID 31036697 DOI: 10.1242/dmm.038711  0.4
2019 Weng T, Ko J, Masamha CP, Xia Z, Xiang Y, Chen NY, Molina JG, Collum S, Mertens TC, Luo F, Philip K, Davies J, Huang J, Wilson C, Thandavarayan RA, ... ... Blackburn MR, et al. Cleavage factor 25 deregulation contributes to pulmonary fibrosis through alternative polyadenylation. The Journal of Clinical Investigation. 130. PMID 30830875 DOI: 10.1172/JCI122106  0.4
2018 Liu H, Adebiyi M, Liu RR, Song A, Manalo J, Wen YE, Wen AQ, Weng T, Ko J, Idowu M, Kellems RE, Eltzschig HK, Blackburn MR, Juneja HS, Xia Y. Elevated ecto-5'-nucleotidase: a missing pathogenic factor and new therapeutic target for sickle cell disease. Blood Advances. 2: 1957-1968. PMID 30097462 DOI: 10.1182/bloodadvances.2018015784  0.4
2018 Mertens TCJ, Hanmandlu A, Tu L, Phan C, Collum SD, Chen NY, Weng T, Davies J, Liu C, Eltzschig HK, Jyothula SSK, Rajagopal K, Xia Y, Guha A, Bruckner BA, ... Blackburn MR, et al. Switching-Off Adora2b in Vascular Smooth Muscle Cells Halts the Development of Pulmonary Hypertension. Frontiers in Physiology. 9: 555. PMID 29910735 DOI: 10.3389/fphys.2018.00555  0.32
2018 Karmouty-Quintana H, Molina JG, Philip K, Bellocchi C, Gudenkauf B, Wu M, Chen NY, Collum SD, Ko J, Agarwal SK, Assassi S, Zhong H, Blackburn MR, Weng T. The Anti-fibrotic Effect of Adenosine A2B Receptor Antagonism in a Mouse Model of Dermal Fibrosis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 29771006 DOI: 10.1002/art.40554  0.76
2017 Xiang Y, Ye Y, Lou Y, Yang Y, Cai C, Zhang Z, Mills T, Chen NY, Kim Y, Muge Ozguc F, Diao L, Karmouty-Quintana H, Xia Y, Kellems RE, Chen Z, ... Blackburn MR, et al. Comprehensive Characterization of Alternative Polyadenylation in Human Cancer. Journal of the National Cancer Institute. PMID 29106591 DOI: 10.1093/jnci/djx223  0.4
2017 Neudecker V, Brodsky KS, Clambey ET, Schmidt EP, Packard TA, Davenport B, Standiford TJ, Weng T, Fletcher AA, Barthel L, Masterson JC, Furuta GT, Cai C, Blackburn MR, Ginde AA, et al. Neutrophil transfer of miR-223 to lung epithelial cells dampens acute lung injury in mice. Science Translational Medicine. 9. PMID 28931657 DOI: 10.1126/scitranslmed.aah5360  0.32
2017 Philip K, Mills TW, Davies J, Chen NY, Karmouty-Quintana H, Luo F, Molina JG, Amione-Guerra J, Sinha N, Guha A, Eltzschig HK, Blackburn MR. HIF1A up-regulates the ADORA2B receptor on alternatively activated macrophages and contributes to pulmonary fibrosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28701304 DOI: 10.1096/fj.201700219R  0.4
2017 Sun K, Liu H, Song A, Manalo JM, D'Alessandro A, Hansen KC, Kellems RE, Eltzschig HK, Blackburn MR, Roach RC, Xia Y. Erythrocyte Purinergic Signaling Components Underlie Hypoxia Adaptation. Journal of Applied Physiology (Bethesda, Md. : 1985). jap.00155.2017. PMID 28572494 DOI: 10.1152/japplphysiol.00155.2017  0.4
2017 Grenz A, Bauerle JD, Dalton JH, Ridyard D, Badulak A, Tak E, McNamee EN, Clambey E, Moldovan R, Reyes G, Klawitter J, Ambler K, Magee K, Christians U, Brodsky KS, ... ... Blackburn MR, et al. Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice. The Journal of Clinical Investigation. 127: 2438. PMID 28569735 DOI: 10.1172/JCI94890  0.32
2016 He B, Hoang TK, Wang T, Ferris M, Taylor CM, Tian X, Luo M, Tran DQ, Zhou J, Tatevian N, Luo F, Molina JG, Blackburn MR, Gomez TH, Roos S, et al. Resetting microbiota by Lactobacillus reuteri inhibits T reg deficiency-induced autoimmunity via adenosine A2A receptors. The Journal of Experimental Medicine. PMID 27994068 DOI: 10.1084/jem.20160961  0.4
2016 Liu H, Zhang Y, Wu H, D'Alessandro A, Yegutkin GG, Song A, Sun K, Li J, Cheng NY, Huang A, Edward Wen Y, Weng TT, Luo F, Nemkov T, Sun H, ... ... Blackburn MR, et al. Beneficial Role of Erythrocyte Adenosine A2B Receptor-Mediated AMP-Activated Protein Kinase Activation in High-Altitude Hypoxia. Circulation. 134: 405-21. PMID 27482003 DOI: 10.1161/CIRCULATIONAHA.116.021311  0.4
2016 Hu X, Adebiyi MG, Luo J, Sun K, Le TT, Zhang Y, Wu H, Zhao S, Karmouty-Quintana H, Liu H, Huang A, Wen YE, Zaika OL, Mamenko M, Pochynyuk OM, ... ... Blackburn MR, et al. Sustained Elevated Adenosine via ADORA2B Promotes Chronic Pain through Neuro-immune Interaction. Cell Reports. PMID 27320922 DOI: 10.1016/j.celrep.2016.05.080  0.4
2016 Wirsdörfer F, de Leve S, Cappuccini F, Eldh T, Meyer AV, Gau E, Thompson LF, Chen NY, Karmouty-Quintana H, Fischer U, Kasper M, Klein D, Ritchey JW, Blackburn MR, Westendorf AM, et al. Extracellular adenosine production by ecto-5'-nucleotidase (CD73) enhances radiation-induced lung fibrosis. Cancer Research. PMID 26921334 DOI: 10.1158/0008-5472.CAN-15-2310  1
2016 Bowser JL, Blackburn MR, Shipley GL, Molina JG, Dunner K, Broaddus RR. Loss of CD73-mediated actin polymerization promotes endometrial tumor progression. The Journal of Clinical Investigation. 126: 220-38. PMID 26642367 DOI: 10.1172/JCI79380  1
2015 Iriyama T, Sun K, Parchim NF, Li J, Zhao C, Song A, Hart LA, Blackwell SC, Sibai BM, Chan LN, Chan TS, Hicks JM, Blackburn MR, Kellems RE, Xia Y. Response to Letter Regarding Article, "Elevated Placental Adenosine Signaling Contributes to the Pathogenesis of Preeclampsia". Circulation. 132: e222-3. PMID 26527698 DOI: 10.1161/CIRCULATIONAHA.115.017262  1
2015 Luo F, Le NB, Mills T, Chen NY, Karmouty-Quintana H, Molina JG, Davies J, Philip K, Volcik KA, Liu H, Xia Y, Eltzschig HK, Blackburn MR. Extracellular adenosine levels are associated with the progression and exacerbation of pulmonary fibrosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26527068 DOI: 10.1096/fj.15-274845  1
2015 Pedroza M, Le TT, Lewis K, Karmouty-Quintana H, To S, George AT, Blackburn MR, Tweardy DJ, Agarwal SK. STAT-3 contributes to pulmonary fibrosis through epithelial injury and fibroblast-myofibroblast differentiation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26324850 DOI: 10.1096/fj.15-273953  1
2015 Evans CM, Raclawska DS, Ttofali F, Liptzin DR, Fletcher AA, Harper DN, McGing MA, McElwee MM, Williams OW, Sanchez E, Roy MG, Kindrachuk KN, Wynn TA, Eltzschig HK, Blackburn MR, et al. The polymeric mucin Muc5ac is required for allergic airway hyperreactivity. Nature Communications. 6: 6281. PMID 25687754 DOI: 10.1038/ncomms7281  1
2015 Sun K, Zhang Y, Bogdanov MV, Wu H, Song A, Li J, Dowhan W, Idowu M, Juneja HS, Molina JG, Blackburn MR, Kellems RE, Xia Y. Elevated adenosine signaling via adenosine A2B receptor induces normal and sickle erythrocyte sphingosine kinase 1 activity. Blood. 125: 1643-52. PMID 25587035 DOI: 10.1182/blood-2014-08-595751  0.4
2015 Iriyama T, Sun K, Parchim NF, Li J, Zhao C, Song A, Hart LA, Blackwell SC, Sibai BM, Chan LN, Chan TS, Hicks MJ, Blackburn MR, Kellems RE, Xia Y. Elevated placental adenosine signaling contributes to the pathogenesis of preeclampsia. Circulation. 131: 730-41. PMID 25538227 DOI: 10.1161/CIRCULATIONAHA.114.013740  1
2015 Karmouty-Quintana H, Philip K, Acero LF, Chen NY, Weng T, Molina JG, Luo F, Davies J, Le NB, Bunge I, Volcik KA, Le TT, Johnston RA, Xia Y, Eltzschig HK, ... Blackburn MR, et al. Deletion of ADORA2B from myeloid cells dampens lung fibrosis and pulmonary hypertension. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 50-60. PMID 25318478 DOI: 10.1096/fj.14-260182  1
2014 Yang W, Hu B, Wu W, Batra S, Blackburn MR, Alcorn JL, Fallon MB, Zhang J. Alveolar type II epithelial cell dysfunction in rat experimental hepatopulmonary syndrome (HPS). Plos One. 9: e113451. PMID 25419825 DOI: 10.1371/journal.pone.0113451  1
2014 Weng T, Poth JM, Karmouty-Quintana H, Garcia-Morales LJ, Melicoff E, Luo F, Chen NY, Evans CM, Bunge RR, Bruckner BA, Loebe M, Volcik KA, Eltzschig HK, Blackburn MR. Hypoxia-induced deoxycytidine kinase contributes to epithelial proliferation in pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine. 190: 1402-12. PMID 25358054 DOI: 10.1164/rccm.201404-0744OC  1
2014 Le TT, Karmouty-Quintana H, Melicoff E, Le TT, Weng T, Chen NY, Pedroza M, Zhou Y, Davies J, Philip K, Molina J, Luo F, George AT, Garcia-Morales LJ, Bunge RR, ... ... Blackburn MR, et al. Blockade of IL-6 Trans signaling attenuates pulmonary fibrosis. Journal of Immunology (Baltimore, Md. : 1950). 193: 3755-68. PMID 25172494 DOI: 10.4049/jimmunol.1302470  1
2014 Dahm PH, Richards JB, Karmouty-Quintana H, Cromar KR, Sur S, Price RE, Malik F, Spencer CY, Barreno RX, Hashmi SS, Blackburn MR, Haque IU, Johnston RA. Effect of antigen sensitization and challenge on oscillatory mechanics of the lung and pulmonary inflammation in obese carboxypeptidase E-deficient mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 307: R621-33. PMID 25009214 DOI: 10.1152/ajpregu.00205.2014  1
2014 Ning C, Wen J, Zhang Y, Dai Y, Wang W, Zhang W, Qi L, Grenz A, Eltzschig HK, Blackburn MR, Kellems RE, Xia Y. Excess adenosine A2B receptor signaling contributes to priapism through HIF-1α mediated reduction of PDE5 gene expression. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 2725-35. PMID 24614760 DOI: 10.1096/fj.13-247833  1
2014 Roy MG, Livraghi-Butrico A, Fletcher AA, McElwee MM, Evans SE, Boerner RM, Alexander SN, Bellinghausen LK, Song AS, Petrova YM, Tuvim MJ, Adachi R, Romo I, Bordt AS, Bowden MG, ... ... Blackburn MR, et al. Muc5b is required for airway defence. Nature. 505: 412-6. PMID 24317696 DOI: 10.1038/nature12807  1
2014 Blackwell TS, Tager AM, Borok Z, Moore BB, Schwartz DA, Anstrom KJ, Bar-Joseph Z, Bitterman P, Blackburn MR, Bradford W, Brown KK, Chapman HA, Collard HR, Cosgrove GP, Deterding R, et al. Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report. American Journal of Respiratory and Critical Care Medicine. 189: 214-22. PMID 24160862 DOI: 10.1164/rccm.201306-1141WS  1
2013 Wang J, Webb-Robertson BJ, Matzke MM, Varnum SM, Brown JN, Riensche RM, Adkins JN, Jacobs JM, Hoidal JR, Scholand MB, Pounds JG, Blackburn MR, Rodland KD, McDermott JE. A semiautomated framework for integrating expert knowledge into disease marker identification. Disease Markers. 35: 513-23. PMID 24223463 DOI: 10.1155/2013/613529  1
2013 Karmouty-Quintana H, Weng T, Garcia-Morales LJ, Chen NY, Pedroza M, Zhong H, Molina JG, Bunge R, Bruckner BA, Xia Y, Johnston RA, Loebe M, Zeng D, Seethamraju H, Belardinelli L, ... Blackburn MR, et al. Adenosine A2B receptor and hyaluronan modulate pulmonary hypertension associated with chronic obstructive pulmonary disease. American Journal of Respiratory Cell and Molecular Biology. 49: 1038-47. PMID 23855769 DOI: 10.1165/rcmb.2013-0089OC  1
2013 Zimmerman MA, Tak E, Ehrentraut SF, Kaplan M, Giebler A, Weng T, Choi DS, Blackburn MR, Kam I, Eltzschig HK, Grenz A. Equilibrative nucleoside transporter (ENT)-1-dependent elevation of extracellular adenosine protects the liver during ischemia and reperfusion. Hepatology (Baltimore, Md.). 58: 1766-78. PMID 23703920 DOI: 10.1002/hep.26505  1
2013 Barreno RX, Richards JB, Schneider DJ, Cromar KR, Nadas AJ, Hernandez CB, Hallberg LM, Price RE, Hashmi SS, Blackburn MR, Haque IU, Johnston RA. Endogenous osteopontin promotes ozone-induced neutrophil recruitment to the lungs and airway hyperresponsiveness to methacholine. American Journal of Physiology. Lung Cellular and Molecular Physiology. 305: L118-29. PMID 23666750 DOI: 10.1152/ajplung.00080.2013  1
2013 Eckle T, Hughes K, Ehrentraut H, Brodsky KS, Rosenberger P, Choi DS, Ravid K, Weng T, Xia Y, Blackburn MR, Eltzschig HK. Crosstalk between the equilibrative nucleoside transporter ENT2 and alveolar Adora2b adenosine receptors dampens acute lung injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 3078-89. PMID 23603835 DOI: 10.1096/fj.13-228551  1
2013 Zhang W, Zhang Y, Wang W, Dai Y, Ning C, Luo R, Sun K, Glover L, Grenz A, Sun H, Tao L, Zhang W, Colgan SP, Blackburn MR, Eltzschig HK, et al. Elevated ecto-5'-nucleotidase-mediated increased renal adenosine signaling via A2B adenosine receptor contributes to chronic hypertension. Circulation Research. 112: 1466-78. PMID 23584256 DOI: 10.1161/CIRCRESAHA.111.300166  1
2013 Li H, Zhang Z, Blackburn MR, Wang SW, Ribelayga CP, O'Brien J. Adenosine and dopamine receptors coregulate photoreceptor coupling via gap junction phosphorylation in mouse retina. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 3135-50. PMID 23407968 DOI: 10.1523/JNEUROSCI.2807-12.2013  1
2013 Weng T, Karmouty-Quintana H, Garcia-Morales LJ, Molina JG, Pedroza M, Bunge RR, Bruckner BA, Loebe M, Seethamraju H, Blackburn MR. Hypoxia-induced deoxycytidine kinase expression contributes to apoptosis in chronic lung disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 2013-26. PMID 23392349 DOI: 10.1096/fj.12-222067  1
2013 Karmouty-Quintana H, Xia Y, Blackburn MR. Adenosine signaling during acute and chronic disease states. Journal of Molecular Medicine (Berlin, Germany). 91: 173-81. PMID 23340998 DOI: 10.1007/s00109-013-0997-1  0.32
2013 Wu H, Chen L, Zhang X, Zhou Q, Li JM, Berger S, Borok Z, Zhou B, Xiao Z, Yin H, Liu M, Wang Y, Jin J, Blackburn MR, Xia Y, et al. Aqp5 is a new transcriptional target of Dot1a and a regulator of Aqp2. Plos One. 8: e53342. PMID 23326416 DOI: 10.1371/journal.pone.0053342  0.32
2012 Carbonaro DA, Jin X, Wang X, Yu XJ, Rozengurt N, Kaufman ML, Wang X, Gjertson D, Zhou Y, Blackburn MR, Kohn DB. Gene therapy/bone marrow transplantation in ADA-deficient mice: roles of enzyme-replacement therapy and cytoreduction. Blood. 120: 3677-87. PMID 22833548 DOI: 10.1182/blood-2012-02-408591  1
2012 Karmouty-Quintana H, Zhong H, Acero L, Weng T, Melicoff E, West JD, Hemnes A, Grenz A, Eltzschig HK, Blackwell TS, Xia Y, Johnston RA, Zeng D, Belardinelli L, Blackburn MR. The A2B adenosine receptor modulates pulmonary hypertension associated with interstitial lung disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 2546-57. PMID 22415303 DOI: 10.1096/fj.11-200907  1
2012 Wu M, Schneider DJ, Mayes MD, Assassi S, Arnett FC, Tan FK, Blackburn MR, Agarwal SK. Osteopontin in systemic sclerosis and its role in dermal fibrosis. The Journal of Investigative Dermatology. 132: 1605-14. PMID 22402440 DOI: 10.1038/jid.2012.32  1
2012 Grenz A, Bauerle JD, Dalton JH, Ridyard D, Badulak A, Tak E, McNamee EN, Clambey E, Moldovan R, Reyes G, Klawitter J, Ambler K, Magee K, Christians U, Brodsky KS, ... ... Blackburn MR, et al. Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice. The Journal of Clinical Investigation. 122: 693-710. PMID 22269324 DOI: 10.1172/JCI60214  1
2012 Blackburn MR, Thompson LF. Adenosine deaminase deficiency: unanticipated benefits from the study of a rare immunodeficiency. Journal of Immunology (Baltimore, Md. : 1950). 188: 933-5. PMID 22262755 DOI: 10.4049/jimmunol.1103519  0.52
2012 Zhang W, Wang W, Yu H, Zhang Y, Dai Y, Ning C, Tao L, Sun H, Kellems RE, Blackburn MR, Xia Y. Interleukin 6 underlies angiotensin II-induced hypertension and chronic renal damage. Hypertension. 59: 136-44. PMID 22068875 DOI: 10.1161/HYPERTENSIONAHA.111.173328  1
2012 Schneider DJ, Wu M, Le TT, Cho SH, Brenner MB, Blackburn MR, Agarwal SK. Cadherin-11 contributes to pulmonary fibrosis: potential role in TGF-β production and epithelial to mesenchymal transition. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 503-12. PMID 21990376 DOI: 10.1096/fj.11-186098  1
2011 Pedroza M, Schneider DJ, Karmouty-Quintana H, Coote J, Shaw S, Corrigan R, Molina JG, Alcorn JL, Galas D, Gelinas R, Blackburn MR. Interleukin-6 contributes to inflammation and remodeling in a model of adenosine mediated lung injury. Plos One. 6: e22667. PMID 21799929 DOI: 10.1371/journal.pone.0022667  1
2011 Allen-Gipson DS, Blackburn MR, Schneider DJ, Zhang H, Bluitt DL, Jarrell JC, Yanov D, Sisson JH, Wyatt TA. Adenosine activation of A(2B) receptor(s) is essential for stimulated epithelial ciliary motility and clearance. American Journal of Physiology. Lung Cellular and Molecular Physiology. 301: L171-80. PMID 21622845 DOI: 10.1152/ajplung.00203.2010  1
2011 Ma W, Ortiz-Quintero B, Rangel R, McKeller MR, Herrera-Rodriguez S, Castillo EF, Schluns KS, Hall M, Zhang H, Suh WK, Okada H, Mak TW, Zhou Y, Blackburn MR, Martinez-Valdez H. Coordinate activation of inflammatory gene networks, alveolar destruction and neonatal death in AKNA deficient mice. Cell Research. 21: 1564-77. PMID 21606955 DOI: 10.1038/cr.2011.84  1
2011 Ghaemi Oskouie F, Shameli A, Yang A, Desrosiers MD, Mucsi AD, Blackburn MR, Yang Y, Santamaria P, Shi Y. High levels of adenosine deaminase on dendritic cells promote autoreactive T cell activation and diabetes in nonobese diabetic mice. Journal of Immunology (Baltimore, Md. : 1950). 186: 6798-806. PMID 21593382 DOI: 10.4049/jimmunol.1004222  1
2011 Wen J, Grenz A, Zhang Y, Dai Y, Kellems RE, Blackburn MR, Eltzschig HK, Xia Y. A2B adenosine receptor contributes to penile erection via PI3K/AKT signaling cascade-mediated eNOS activation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2823-30. PMID 21566208 DOI: 10.1096/fj.11-181057  1
2011 Thompson LF, Picher M, Blackburn MR. Animal models of airway diseases. Sub-Cellular Biochemistry. 55: 195-234. PMID 21560049 DOI: 10.1007/978-94-007-1217-1_8  0.52
2011 Abbott AN, Welsh KJ, Hwang SA, Płoszaj P, Choudhury T, Boyd S, Blackburn MR, Hunter RL, Actor JK. IL-6 mediates 11βHSD type 2 to effect progression of the mycobacterial cord factor trehalose 6,6'-dimycolate-induced granulomatous response. Neuroimmunomodulation. 18: 212-25. PMID 21389736 DOI: 10.1159/000323776  1
2011 Blackburn MR. P2Y6 and vascular inflammation. Blood. 117: 2304-5. PMID 21350062 DOI: 10.1182/blood-2011-01-327973  1
2011 Zhang Y, Dai Y, Wen J, Zhang W, Grenz A, Sun H, Tao L, Lu G, Alexander DC, Milburn MV, Carter-Dawson L, Lewis DE, Zhang W, Eltzschig HK, Kellems RE, ... Blackburn MR, et al. Detrimental effects of adenosine signaling in sickle cell disease. Nature Medicine. 17: 79-86. PMID 21170046 DOI: 10.1038/nm.2280  1
2011 Zhou Y, Schneider DJ, Morschl E, Song L, Pedroza M, Karmouty-Quintana H, Le T, Sun CX, Blackburn MR. Distinct roles for the A2B adenosine receptor in acute and chronic stages of bleomycin-induced lung injury. Journal of Immunology (Baltimore, Md. : 1950). 186: 1097-106. PMID 21149612 DOI: 10.4049/jimmunol.1002907  1
2010 Csóka B, Németh ZH, Rosenberger P, Eltzschig HK, Spolarics Z, Pacher P, Selmeczy Z, Koscsó B, Himer L, Vizi ES, Blackburn MR, Deitch EA, Haskó G. A2B adenosine receptors protect against sepsis-induced mortality by dampening excessive inflammation. Journal of Immunology (Baltimore, Md. : 1950). 185: 542-50. PMID 20505145 DOI: 10.4049/jimmunol.0901295  1
2010 Lu Q, Harrington EO, Newton J, Casserly B, Radin G, Warburton R, Zhou Y, Blackburn MR, Rounds S. Adenosine protected against pulmonary edema through transporter- and receptor A2-mediated endothelial barrier enhancement. American Journal of Physiology. Lung Cellular and Molecular Physiology. 298: L755-67. PMID 20228181 DOI: 10.1152/ajplung.00330.2009  1
2010 Zhou Y, Murthy JN, Zeng D, Belardinelli L, Blackburn MR. Alterations in adenosine metabolism and signaling in patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis. Plos One. 5: e9224. PMID 20169073 DOI: 10.1371/journal.pone.0009224  0.36
2010 Yang A, Mucsi AD, Desrosiers MD, Chen JF, Schnermann JB, Blackburn MR, Shi Y. Adenosine mediated desensitization of cAMP signaling enhances T-cell responses. European Journal of Immunology. 40: 449-59. PMID 19950175 DOI: 10.1002/eji.200939586  0.32
2010 Wen J, Jiang X, Dai Y, Zhang Y, Tang Y, Sun H, Mi T, Phatarpekar PV, Kellems RE, Blackburn MR, Xia Y. Increased adenosine contributes to penile fibrosis, a dangerous feature of priapism, via A2B adenosine receptor signaling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 740-9. PMID 19858092 DOI: 10.1096/fj.09-144147  1
2010 Wen J, Jiang X, Dai Y, Zhang Y, Tang Y, Sun H, Mi T, Kellems RE, Blackburn MR, Xia Y. Adenosine deaminase enzyme therapy prevents and reverses the heightened cavernosal relaxation in priapism. The Journal of Sexual Medicine. 7: 3011-22. PMID 19845544 DOI: 10.1111/j.1743-6109.2009.01552.x  1
2010 Schneider DJ, Lindsay JC, Zhou Y, Molina JG, Blackburn MR. Adenosine and osteopontin contribute to the development of chronic obstructive pulmonary disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 70-80. PMID 19720619 DOI: 10.1096/fj.09-140772  1
2010 Zaynagetdinov R, Ryzhov S, Goldstein AE, Yin H, Novitskiy SV, Goleniewska K, Polosukhin VV, Newcomb DC, Mitchell D, Morschl E, Zhou Y, Blackburn MR, Peebles RS, Biaggioni I, Feoktistov I. Attenuation of chronic pulmonary inflammation in A2B adenosine receptor knockout mice. American Journal of Respiratory Cell and Molecular Biology. 42: 564-71. PMID 19556606 DOI: 10.1165/rcmb.2008-0391OC  0.36
2009 Blackburn MR, Vance CO, Morschl E, Wilson CN. Adenosine receptors and inflammation. Handbook of Experimental Pharmacology. 215-69. PMID 19639284 DOI: 10.1007/978-3-540-89615-9_8  0.36
2009 Zhou Y, Mohsenin A, Morschl E, Young HW, Molina JG, Ma W, Sun CX, Martinez-Valdez H, Blackburn MR. Enhanced airway inflammation and remodeling in adenosine deaminase-deficient mice lacking the A2B adenosine receptor. Journal of Immunology (Baltimore, Md. : 1950). 182: 8037-46. PMID 19494329 DOI: 10.4049/jimmunol.0900515  1
2009 Zhou Y, Schneider DJ, Blackburn MR. Adenosine signaling and the regulation of chronic lung disease. Pharmacology & Therapeutics. 123: 105-16. PMID 19426761 DOI: 10.1016/j.pharmthera.2009.04.003  1
2009 Dai Y, Zhang Y, Phatarpekar P, Mi T, Zhang H, Blackburn MR, Xia Y. Adenosine signaling, priapism and novel therapies. The Journal of Sexual Medicine. 6: 292-301. PMID 19267852 DOI: 10.1111/j.1743-6109.2008.01187.x  0.32
2008 Joachims ML, Marble PA, Laurent AB, Pastuszko P, Paliotta M, Blackburn MR, Thompson LF. Restoration of adenosine deaminase-deficient human thymocyte development in vitro by inhibition of deoxynucleoside kinases. Journal of Immunology (Baltimore, Md. : 1950). 181: 8153-61. PMID 19018008  0.52
2008 Joachims ML, Marble P, Knott-Craig C, Pastuszko P, Blackburn MR, Thompson LF. Inhibition of deoxynucleoside kinases in human thymocytes prevents dATP accumulation and induction of apoptosis. Nucleosides, Nucleotides & Nucleic Acids. 27: 816-20. PMID 18600545 DOI: 10.1080/15257770802146270  0.52
2008 Morschl E, Molina JG, Volmer JB, Mohsenin A, Pero RS, Hong JS, Kheradmand F, Lee JJ, Blackburn MR. A3 adenosine receptor signaling influences pulmonary inflammation and fibrosis. American Journal of Respiratory Cell and Molecular Biology. 39: 697-705. PMID 18587054 DOI: 10.1165/rcmb.2007-0419OC  1
2008 Welsh KJ, Abbott AN, Hwang SA, Indrigo J, Armitige LY, Blackburn MR, Hunter RL, Actor JK. A role for tumour necrosis factor-alpha, complement C5 and interleukin-6 in the initiation and development of the mycobacterial cord factor trehalose 6,6'-dimycolate induced granulomatous response. Microbiology (Reading, England). 154: 1813-24. PMID 18524936 DOI: 10.1099/mic.0.2008/016923-0  1
2008 Takedachi M, Qu D, Ebisuno Y, Oohara H, Joachims ML, McGee ST, Maeda E, McEver RP, Tanaka T, Miyasaka M, Murakami S, Krahn T, Blackburn MR, Thompson LF. CD73-generated adenosine restricts lymphocyte migration into draining lymph nodes. Journal of Immunology (Baltimore, Md. : 1950). 180: 6288-96. PMID 18424752  0.52
2008 Carbonaro DA, Jin X, Cotoi D, Mi T, Yu XJ, Skelton DC, Dorey F, Kellems RE, Blackburn MR, Kohn DB. Neonatal bone marrow transplantation of ADA-deficient SCID mice results in immunologic reconstitution despite low levels of engraftment and an absence of selective donor T lymphoid expansion. Blood. 111: 5745-54. PMID 18356486 DOI: 10.1182/blood-2007-08-103663  1
2008 Mi T, Abbasi S, Zhang H, Uray K, Chunn JL, Xia LW, Molina JG, Weisbrodt NW, Kellems RE, Blackburn MR, Xia Y. Excess adenosine in murine penile erectile tissues contributes to priapism via A2B adenosine receptor signaling. The Journal of Clinical Investigation. 118: 1491-501. PMID 18340377 DOI: 10.1172/JCI33467  1
2008 Lewis CC, Yang JY, Huang X, Banerjee SK, Blackburn MR, Baluk P, McDonald DM, Blackwell TS, Nagabhushanam V, Peters W, Voehringer D, Erle DJ. Disease-specific gene expression profiling in multiple models of lung disease. American Journal of Respiratory and Critical Care Medicine. 177: 376-87. PMID 18029791 DOI: 10.1164/rccm.200702-333OC  1
2007 Mohsenin A, Mi T, Xia Y, Kellems RE, Chen JF, Blackburn MR. Genetic removal of the A2A adenosine receptor enhances pulmonary inflammation, mucin production, and angiogenesis in adenosine deaminase-deficient mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L753-61. PMID 17601796 DOI: 10.1152/ajplung.00187.2007  1
2007 Ochkur SI, Jacobsen EA, Protheroe CA, Biechele TL, Pero RS, McGarry MP, Wang H, O'Neill KR, Colbert DC, Colby TV, Shen H, Blackburn MR, Irvin CC, Lee JJ, Lee NA. Coexpression of IL-5 and eotaxin-2 in mice creates an eosinophil-dependent model of respiratory inflammation with characteristics of severe asthma. Journal of Immunology (Baltimore, Md. : 1950). 178: 7879-89. PMID 17548626  1
2007 Csóka B, Németh ZH, Virág L, Gergely P, Leibovich SJ, Pacher P, Sun CX, Blackburn MR, Vizi ES, Deitch EA, Haskó G. A2A adenosine receptors and C/EBPbeta are crucially required for IL-10 production by macrophages exposed to Escherichia coli. Blood. 110: 2685-95. PMID 17525287 DOI: 10.1182/blood-2007-01-065870  1
2007 Blackburn MR. A role for neural pathways in adenosine-induced bronchoconstriction. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L22-4. PMID 17513454 DOI: 10.1152/ajplung.00196.2007  1
2007 Young HW, Williams OW, Chandra D, Bellinghausen LK, Pérez G, Suárez A, Tuvim MJ, Roy MG, Alexander SN, Moghaddam SJ, Adachi R, Blackburn MR, Dickey BF, Evans CM. Central role of Muc5ac expression in mucous metaplasia and its regulation by conserved 5' elements. American Journal of Respiratory Cell and Molecular Biology. 37: 273-90. PMID 17463395 DOI: 10.1165/rcmb.2005-0460OC  1
2007 Mohsenin A, Burdick MD, Molina JG, Keane MP, Blackburn MR. Enhanced CXCL1 production and angiogenesis in adenosine-mediated lung disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1026-36. PMID 17227950 DOI: 10.1096/fj.06-7301com  1
2006 Sun CX, Zhong H, Mohsenin A, Morschl E, Chunn JL, Molina JG, Belardinelli L, Zeng D, Blackburn MR. Role of A2B adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury. The Journal of Clinical Investigation. 116: 2173-2182. PMID 16841096 DOI: 10.1172/JCI27303  1
2006 Young HW, Sun CX, Evans CM, Dickey BF, Blackburn MR. A3 adenosine receptor signaling contributes to airway mucin secretion after allergen challenge. American Journal of Respiratory Cell and Molecular Biology. 35: 549-58. PMID 16763221 DOI: 10.1165/rcmb.2006-0060OC  1
2006 Ma B, Blackburn MR, Lee CG, Homer RJ, Liu W, Flavell RA, Boyden L, Lifton RP, Sun CX, Young HW, Elias JA. Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis. The Journal of Clinical Investigation. 116: 1274-83. PMID 16670768 DOI: 10.1172/JCI26372  1
2006 Van De Wiele CJ, Joachims ML, Fesler AM, Vaughn JG, Blackburn MR, McGee ST, Thompson LF. Further differentiation of murine double-positive thymocytes is inhibited in adenosine deaminase-deficient murine fetal thymic organ culture. Journal of Immunology (Baltimore, Md. : 1950). 176: 5925-33. PMID 16670300  0.52
2006 Carbonaro DA, Jin X, Petersen D, Wang X, Dorey F, Kil KS, Aldrich M, Blackburn MR, Kellems RE, Kohn DB. In vivo transduction by intravenous injection of a lentiviral vector expressing human ADA into neonatal ADA gene knockout mice: a novel form of enzyme replacement therapy for ADA deficiency. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 1110-20. PMID 16651028 DOI: 10.1016/j.ymthe.2006.02.013  1
2006 Willems L, Reichelt ME, Molina JG, Sun CX, Chunn JL, Ashton KJ, Schnermann J, Blackburn MR, Headrick JP. Effects of adenosine deaminase and A1 receptor deficiency in normoxic and ischaemic mouse hearts. Cardiovascular Research. 71: 79-87. PMID 16626672 DOI: 10.1016/j.cardiores.2006.03.006  1
2006 Volmer JB, Thompson LF, Blackburn MR. Ecto-5'-nucleotidase (CD73)-mediated adenosine production is tissue protective in a model of bleomycin-induced lung injury. Journal of Immunology (Baltimore, Md. : 1950). 176: 4449-58. PMID 16547283  1
2006 Mohsenin A, Blackburn MR. Adenosine signaling in asthma and chronic obstructive pulmonary disease. Current Opinion in Pulmonary Medicine. 12: 54-9. PMID 16357580 DOI: 10.1097/01.mcp.0000199002.46038.cb  1
2006 Chunn JL, Mohsenin A, Young HW, Lee CG, Elias JA, Kellems RE, Blackburn MR. Partially adenosine deaminase-deficient mice develop pulmonary fibrosis in association with adenosine elevations. American Journal of Physiology. Lung Cellular and Molecular Physiology. 290: L579-87. PMID 16258000 DOI: 10.1152/ajplung.00258.2005  1
2005 Chunn JL, Molina JG, Mi T, Xia Y, Kellems RE, Blackburn MR. Adenosine-dependent pulmonary fibrosis in adenosine deaminase-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 175: 1937-46. PMID 16034138  1
2005 Blackburn MR, Kellems RE. Adenosine deaminase deficiency: metabolic basis of immune deficiency and pulmonary inflammation. Advances in Immunology. 86: 1-41. PMID 15705418 DOI: 10.1016/S0065-2776(04)86001-2  1
2005 Reichelt ME, Willems L, Molina JG, Sun CX, Noble JC, Ashton KJ, Schnermann J, Blackburn MR, Headrick JP. Genetic deletion of the A1 adenosine receptor limits myocardial ischemic tolerance. Circulation Research. 96: 363-7. PMID 15653569 DOI: 10.1161/01.RES.0000156075.00127.C3  1
2005 Sun CX, Young HW, Molina JG, Volmer JB, Schnermann J, Blackburn MR. A protective role for the A1 adenosine receptor in adenosine-dependent pulmonary injury. The Journal of Clinical Investigation. 115: 35-43. PMID 15630442 DOI: 10.1172/JCI22656  1
2004 Young HW, Molina JG, Dimina D, Zhong H, Jacobson M, Chan LN, Chan TS, Lee JJ, Blackburn MR. A3 adenosine receptor signaling contributes to airway inflammation and mucus production in adenosine deaminase-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 173: 1380-9. PMID 15240734  1
2004 Evans CM, Williams OW, Tuvim MJ, Nigam R, Mixides GP, Blackburn MR, DeMayo FJ, Burns AR, Smith C, Reynolds SD, Stripp BR, Dickey BF. Mucin is produced by clara cells in the proximal airways of antigen-challenged mice. American Journal of Respiratory Cell and Molecular Biology. 31: 382-94. PMID 15191915 DOI: 10.1165/rcmb.2004-0060OC  1
2004 Babich LG, Ku CY, Young HW, Huang H, Blackburn MR, Sanborn BM. Expression of capacitative calcium TrpC proteins in rat myometrium during pregnancy. Biology of Reproduction. 70: 919-24. PMID 14627551 DOI: 10.1095/biolreprod.103.023325  1
2004 Banerjee SK, Young HW, Barczak A, Erle DJ, Blackburn MR. Abnormal alveolar development associated with elevated adenine nucleosides. American Journal of Respiratory Cell and Molecular Biology. 30: 38-50. PMID 12855405 DOI: 10.1165/rcmb.2003-0102OC  1
2003 Aldrich MB, Chen W, Blackburn MR, Martinez-Valdez H, Datta SK, Kellems RE. Impaired germinal center maturation in adenosine deaminase deficiency. Journal of Immunology (Baltimore, Md. : 1950). 171: 5562-70. PMID 14607964  1
2003 Thompson LF, Vaughn JG, Laurent AB, Blackburn MR, Van De Wiele CJ. Mechanisms of apoptosis in developing thymocytes as revealed by adenosine deaminase-deficient fetal thymic organ cultures. Biochemical Pharmacology. 66: 1595-9. PMID 14555239  0.52
2003 Blackburn MR, Lee CG, Young HW, Zhu Z, Chunn JL, Kang MJ, Banerjee SK, Elias JA. Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway. The Journal of Clinical Investigation. 112: 332-44. PMID 12897202 DOI: 10.1172/JCI16815  1
2003 Zhong H, Shlykov SG, Molina JG, Sanborn BM, Jacobson MA, Tilley SL, Blackburn MR. Activation of murine lung mast cells by the adenosine A3 receptor. Journal of Immunology (Baltimore, Md. : 1950). 171: 338-45. PMID 12817016  1
2003 Blackburn MR. Too much of a good thing: adenosine overload in adenosine-deaminase-deficient mice. Trends in Pharmacological Sciences. 24: 66-70. PMID 12559769 DOI: 10.1016/S0165-6147(02)00045-7  1
2002 Van De Wiele CJ, Vaughn JG, Blackburn MR, Ledent CA, Jacobson M, Jiang H, Thompson LF. Adenosine kinase inhibition promotes survival of fetal adenosine deaminase-deficient thymocytes by blocking dATP accumulation. The Journal of Clinical Investigation. 110: 395-402. PMID 12163459 DOI: 10.1172/JCI15683  0.52
2002 Banerjee SK, Young HW, Volmer JB, Blackburn MR. Gene expression profiling in inflammatory airway disease associated with elevated adenosine. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L169-82. PMID 11792620 DOI: 10.1152/ajplung.00243.2001  1
2001 Chunn JL, Young HW, Banerjee SK, Colasurdo GN, Blackburn MR. Adenosine-dependent airway inflammation and hyperresponsiveness in partially adenosine deaminase-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 167: 4676-85. PMID 11591798  1
2001 Zhong H, Chunn JL, Volmer JB, Fozard JR, Blackburn MR. Adenosine-mediated mast cell degranulation in adenosine deaminase-deficient mice. The Journal of Pharmacology and Experimental Therapeutics. 298: 433-40. PMID 11454903  1
2000 Blackburn MR, Aldrich M, Volmer JB, Chen W, Zhong H, Kelly S, Hershfield MS, Datta SK, Kellems RE. The use of enzyme therapy to regulate the metabolic and phenotypic consequences of adenosine deaminase deficiency in mice. Differential impact on pulmonary and immunologic abnormalities. The Journal of Biological Chemistry. 275: 32114-21. PMID 10908569 DOI: 10.1074/jbc.M005153200  1
2000 Blackburn MR, Volmer JB, Thrasher JL, Zhong H, Crosby JR, Lee JJ, Kellems RE. Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction. The Journal of Experimental Medicine. 192: 159-70. PMID 10899903 DOI: 10.1084/jem.192.2.159  1
1999 Blackburn MR, Wubah JA, Chunn JL, Thompson LF, Knudsen TB. Transitory expression of the A2b adenosine receptor during implantation chamber development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 216: 127-36. PMID 10536053 DOI: 10.1002/(SICI)1097-0177(199910)216:2<127::AID-DVDY4>3.0.CO;2-C  1
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