Louis B. Hersh - Publications

University of Kentucky, Lexington, KY 

125 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Chow KM, Whiteheart SW, Smiley JR, Sharma S, Boaz K, Coleman MJ, Maynard A, Hersh LB, Vander Kooi CW. Immunization of Alpacas (Lama pacos) with Protein Antigens and Production of Antigen-specific Single Domain Antibodies. Journal of Visualized Experiments : Jove. PMID 30741259 DOI: 10.3791/58471  0.56
2018 Song ES, Rodgers DW, Hersh LB. Insulin-degrading enzyme is not secreted from cultured cells. Scientific Reports. 8: 2335. PMID 29402917 DOI: 10.1038/S41598-018-20597-6  0.36
2017 Song ES, Jang H, Guo HF, Juliano MA, Juliano L, Morris AJ, Galperin E, Rodgers DW, Hersh LB. Inositol phosphates and phosphoinositides activate insulin-degrading enzyme, while phosphoinositides also mediate binding to endosomes. Proceedings of the National Academy of Sciences of the United States of America. PMID 28325868 DOI: 10.1073/Pnas.1613447114  0.36
2016 Liu M, Verma N, Peng X, Srodulski S, Morris A, Chow M, Hersh LB, Chen J, Zhu H, Netea MG, Margulies KB, Despa S, Despa F. Hyperamylinemia Increases IL-1β Synthesis in the Heart via Peroxidative Sarcolemmal Injury. Diabetes. PMID 27335231 DOI: 10.2337/Db16-0044  0.32
2016 Verma N, Ly H, Liu M, Chen J, Zhu H, Chow M, Hersh LB, Despa F. Intraneuronal Amylin Deposition Peroxidative Membrane Injury and Increased IL-1β Synthesis in Brains of Alzheimer's Disease Patients with Type-2 Diabetes and in Diabetic HIP Rats. Journal of Alzheimer's Disease : Jad. PMID 27163815 DOI: 10.3233/Jad-160047  0.32
2016 Despa F, Verma N, Ly H, Liu M, Chen J, Zhu H, Hersh L. Intraneuronal Amylin Deposition, Peroxidative Membrane Injury And Increased Il-1Ss Synthesis In Brains Of Alzheimer’S Disease Patients With Type-2 Diabetes And Diabetic Hip Rats Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.1264  0.32
2015 Guan H, Chow KM, Song E, Verma N, Despa F, Hersh LB. The Mitochondrial Peptidase Pitrilysin Degrades Islet Amyloid Polypeptide in Beta-Cells. Plos One. 10: e0133263. PMID 26191799 DOI: 10.1371/Journal.Pone.0133263  0.56
2015 Song ES, Ozbil M, Zhang T, Sheetz M, Lee D, Tran D, Li S, Prabhakar R, Hersh LB, Rodgers DW. An Extended Polyanion Activation Surface in Insulin Degrading Enzyme. Plos One. 10: e0133114. PMID 26186535 DOI: 10.1371/Journal.Pone.0133114  0.36
2015 Parthasarathy R, Chow KM, Derafshi Z, Fautsch MP, Hetling JR, Rodgers DW, Hersh LB, Pepperberg DR. Reduction of amyloid-beta levels in mouse eye tissues by intra-vitreally delivered neprilysin. Experimental Eye Research. PMID 26142956 DOI: 10.1016/J.Exer.2015.06.027  0.32
2015 Chin-Chan M, Segovia J, Quintanar L, Arcos-López T, Hersh LB, Chow KM, Rodgers DW, Quintanilla-Vega B. Mercury Reduces the Enzymatic Activity of Neprilysin in Differentiated SH-SY5Y Cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 145: 128-37. PMID 25673500 DOI: 10.1093/Toxsci/Kfv037  0.56
2015 Guan H, Chow KM, Song E, Verma N, Despa F, Hersh LB. The mitochondrial peptidase pitrilysin degrades islet amyloid polypeptide in beta-cells Plos One. 10. DOI: 10.1371/journal.pone.0133263  0.32
2015 Song ES, Ozbil M, Zhang T, Sheetz M, Lee D, Tran D, Li S, Prabhakar R, Hersh LB, Rodgers DW. An extended polyanion activation surface in insulin degrading enzyme Plos One. 10. DOI: 10.1371/journal.pone.0133114  0.56
2014 Niedowicz DM, Reeves VL, Platt TL, Kohler K, Beckett TL, Powell DK, Lee TL, Sexton TR, Song ES, Brewer LD, Latimer CS, Kraner SD, Larson KL, Ozcan S, Norris CM, ... Hersh LB, et al. Obesity and diabetes cause cognitive dysfunction in the absence of accelerated β-amyloid deposition in a novel murine model of mixed or vascular dementia. Acta Neuropathologica Communications. 2: 64. PMID 24916066 DOI: 10.1186/2051-5960-2-64  0.56
2013 Karoor V, Oka M, Walchak SJ, Hersh LB, Miller YE, Dempsey EC. Neprilysin regulates pulmonary artery smooth muscle cell phenotype through a platelet-derived growth factor receptor-dependent mechanism. Hypertension. 61: 921-30. PMID 23381789 DOI: 10.1161/Hypertensionaha.111.199588  0.56
2012 Song ES, Melikishvili M, Fried MG, Juliano MA, Juliano L, Rodgers DW, Hersh LB. Cysteine 904 is required for maximal insulin degrading enzyme activity and polyanion activation. Plos One. 7: e46790. PMID 23077523 DOI: 10.1371/Journal.Pone.0046790  0.56
2012 Guan H, Chow KM, Shah R, Rhodes CJ, Hersh LB. Degradation of islet amyloid polypeptide by neprilysin. Diabetologia. 55: 2989-98. PMID 22898766 DOI: 10.1007/S00125-012-2678-Y  0.56
2012 Sexton T, Hitchcook LJ, Rodgers DW, Bradley LH, Hersh LB. Active site mutations change the cleavage specificity of neprilysin. Plos One. 7: e32343. PMID 22384224 DOI: 10.1371/Journal.Pone.0032343  0.56
2012 Holler CJ, Webb RL, Laux AL, Beckett TL, Niedowicz DM, Ahmed RR, Liu Y, Simmons CR, Dowling AL, Spinelli A, Khurgel M, Estus S, Head E, Hersh LB, Murphy MP. BACE2 expression increases in human neurodegenerative disease. The American Journal of Pathology. 180: 337-50. PMID 22074738 DOI: 10.1016/J.Ajpath.2011.09.034  0.56
2012 Noinaj N, Song ES, Bhasin S, Alper BJ, Schmidt WK, Hersh LB, Rodgers DW. Anion activation site of insulin-degrading enzyme. The Journal of Biological Chemistry. 287: 48-57. PMID 22049080 DOI: 10.1074/Jbc.M111.264614  0.56
2011 Noinaj N, Bhasin SK, Song ES, Scoggin KE, Juliano MA, Juliano L, Hersh LB, Rodgers DW. Identification of the allosteric regulatory site of insulysin. Plos One. 6: e20864. PMID 21731629 DOI: 10.1371/Journal.Pone.0020864  0.56
2011 Song ES, Rodgers DW, Hersh LB. Mixed dimers of insulin-degrading enzyme reveal a cis activation mechanism. The Journal of Biological Chemistry. 286: 13852-8. PMID 21343292 DOI: 10.1074/Jbc.M110.191668  0.36
2011 Kessler JH, Khan S, Seifert U, Le Gall S, Chow KM, Paschen A, Bres-Vloemans SA, De Ru A, Van Montfoort N, Franken KLMC, Benckhuijsen WE, Brooks JM, Van Hall T, Ray K, Mulder A, ... ... Hersh LB, et al. Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes Nature Immunology. 12: 45-53. PMID 21151101 DOI: 10.1038/Ni.1974  0.56
2011 Wick MJ, Buesing EJ, Wehling CA, Loomis ZL, Cool CD, Zamora MR, Miller YE, Colgan SP, Hersh LB, Voelkel NF, Dempsey EC. Decreased neprilysin and pulmonary vascular remodeling in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 183: 330-40. PMID 20813891 DOI: 10.1164/rccm.201002-0154OC  0.56
2011 Song ES, Rodgers DW, Hersh LB. Mixed dimers of insulin-degrading enzyme reveal a cis activation mechanism Journal of Biological Chemistry. 286: 13853-13858. DOI: 10.1074/jbc.M110.191668  0.56
2010 Chow KM, Guan H, Hersh LB. Aminopeptidases do not directly degrade tau protein. Molecular Neurodegeneration. 5: 48. PMID 21054848 DOI: 10.1186/1750-1326-5-48  0.56
2010 Liu Y, Studzinski C, Beckett T, Murphy MP, Klein RL, Hersh LB. Circulating neprilysin clears brain amyloid. Molecular and Cellular Neurosciences. 45: 101-7. PMID 20558294 DOI: 10.1016/J.Mcn.2010.05.014  0.56
2010 Song ES, Rodgers DW, Hersh LB. A monomeric variant of insulin degrading enzyme (IDE) loses its regulatory properties Plos One. 5. PMID 20300529 DOI: 10.1371/Journal.Pone.0009719  0.56
2009 Liu Y, Studzinski C, Beckett T, Guan H, Hersh MA, Murphy MP, Klein R, Hersh LB. Expression of neprilysin in skeletal muscle reduces amyloid burden in a transgenic mouse model of Alzheimer disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1381-6. PMID 19471248 DOI: 10.1038/Mt.2009.115  0.56
2009 Dempsey EC, Wick MJ, Karoor V, Barr EJ, Tallman DW, Wehling CA, Walchak SJ, Laudi S, Le M, Oka M, Majka S, Cool CD, Fagan KA, Klemm DJ, Hersh LB, et al. Neprilysin null mice develop exaggerated pulmonary vascular remodeling in response to chronic hypoxia. The American Journal of Pathology. 174: 782-96. PMID 19234135 DOI: 10.2353/Ajpath.2009.080345  0.56
2009 Chow KM, Gakh O, Payne IC, Juliano MA, Juliano L, Isaya G, Hersh LB. Mammalian pitrilysin: substrate specificity and mitochondrial targeting. Biochemistry. 48: 2868-77. PMID 19196155 DOI: 10.1021/Bi8016125  0.56
2009 Rose JB, Crews L, Rockenstein E, Adame A, Mante M, Hersh LB, Gage FH, Spencer B, Potkar R, Marr RA, Masliah E. Neuropeptide Y fragments derived from neprilysin processing are neuroprotective in a transgenic model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1115-25. PMID 19176820 DOI: 10.1523/Jneurosci.4220-08.2009  0.56
2009 Guan H, Liu Y, Daily A, Police S, Kim MH, Oddo S, LaFerla FM, Pauly JR, Murphy MP, Hersh LB. Peripherally expressed neprilysin reduces brain amyloid burden: a novel approach for treating Alzheimer's disease. Journal of Neuroscience Research. 87: 1462-73. PMID 19021293 DOI: 10.1002/Jnr.21944  0.56
2008 Hersh LB, Rodgers DW. Neprilysin and amyloid beta peptide degradation Current Alzheimer Research. 5: 225-231. PMID 18393807 DOI: 10.2174/156720508783954703  0.56
2008 Horiguchi A, Chen DY, Goodman OB, Zheng R, Shen R, Guan H, Hersh LB, Nanus DM. Neutral endopeptidase inhibits prostate cancer tumorigenesis by reducing FGF-2-mediated angiogenesis. Prostate Cancer and Prostatic Diseases. 11: 79-87. PMID 17563767 DOI: 10.1038/Sj.Pcan.4500984  0.56
2007 Liu Y, Guan H, Beckett TL, Juliano MA, Juliano L, Song ES, Chow KM, Murphy MP, Hersh LB. In vitro and in vivo degradation of Abeta peptide by peptidases coupled to erythrocytes. Peptides. 28: 2348-55. PMID 17988763 DOI: 10.1016/J.Peptides.2007.09.015  0.56
2007 Horiguchi A, Zheng R, Goodman OB, Shen R, Guan H, Hersh LB, Nanus DM. Lentiviral vector neutral endopeptidase gene transfer suppresses prostate cancer tumor growth. Cancer Gene Therapy. 14: 583-9. PMID 17415380 DOI: 10.1038/Sj.Cgt.7701047  0.56
2007 Kim M, Hersh LB, Leissring MA, Ingelsson M, Matsui T, Farris W, Lu A, Hyman BT, Selkoe DJ, Bertram L, Tanzi RE. Decreased catalytic activity of the insulin-degrading enzyme in chromosome 10-linked Alzheimer disease families. The Journal of Biological Chemistry. 282: 7825-32. PMID 17244626 DOI: 10.1074/Jbc.M609168200  0.56
2007 Horiguchi A, Shen R, Zheng R, Goodman OB, Guan H, Hersh LB, Nanus DM. 149: Lentiviral Vector Neutral Endopeptidase Gene Transfer Suppresses Prostate Cancer Tumor Growth The Journal of Urology. 177: 51-51. DOI: 10.1016/S0022-5347(18)30414-2  0.56
2006 Song ES, Cady C, Fried MG, Hersh LB. Proteolytic fragments of insulysin (IDE) retain substrate binding but lose allosteric regulation. Biochemistry. 45: 15085-91. PMID 17154546 DOI: 10.1021/Bi061298U  0.56
2006 Stricker R, Chow KM, Walther D, Hanck T, Hersh LB, Reiser G. Interaction of the brain-specific protein p42IP4/centaurin-alpha1 with the peptidase nardilysin is regulated by the cognate ligands of p42IP4, PtdIns(3,4,5)P3 and Ins(1,3,4,5)P4, with stereospecificity. Journal of Neurochemistry. 98: 343-54. PMID 16805830 DOI: 10.1111/J.1471-4159.2006.03869.X  0.56
2006 Shimojo M, Hersh LB. Characterization of the REST/NRSF-interacting LIM domain protein (RILP): localization and interaction with REST/NRSF. Journal of Neurochemistry. 96: 1130-8. PMID 16417580 DOI: 10.1111/J.1471-4159.2005.03608.X  0.56
2005 Shinall H, Song ES, Hersh LB. Susceptibility of amyloid beta peptide degrading enzymes to oxidative damage: a potential Alzheimer's disease spiral. Biochemistry. 44: 15345-50. PMID 16285738 DOI: 10.1021/Bi050650L  0.32
2005 Chow KM, Ma Z, Cai J, Pierce WM, Hersh LB. Nardilysin facilitates complex formation between mitochondrial malate dehydrogenase and citrate synthase. Biochimica Et Biophysica Acta. 1723: 292-301. PMID 15809022 DOI: 10.1016/J.Bbagen.2005.02.010  0.56
2005 Song ES, Hersh LB. Insulysin: an allosteric enzyme as a target for Alzheimer's disease. Journal of Molecular Neuroscience : Mn. 25: 201-6. PMID 15800373 DOI: 10.1385/Jmn:25:3:201  0.56
2005 Lazarov O, Robinson J, Tang YP, Hairston IS, Korade-Mirnics Z, Lee VM, Hersh LB, Sapolsky RM, Mirnics K, Sisodia SS. Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice. Cell. 120: 701-13. PMID 15766532 DOI: 10.1016/J.Cell.2005.01.015  0.56
2005 Song ES, Daily A, Fried MG, Juliano MA, Juliano L, Hersh LB. Mutation of active site residues of insulin-degrading enzyme alters allosteric interactions. The Journal of Biological Chemistry. 280: 17701-6. PMID 15749695 DOI: 10.1074/Jbc.M501896200  0.56
2005 Nath A, Hersh LB. Tat and amyloid: multiple interactions. Aids (London, England). 19: 203-4. PMID 15668546 DOI: 10.1097/00002030-200501280-00013  0.56
2004 Yao J, Erickson JD, Hersh LB. Protein kinase A affects trafficking of the vesicular monoamine transporters in PC12 cells. Traffic (Copenhagen, Denmark). 5: 1006-16. PMID 15522101 DOI: 10.1111/J.1600-0854.2004.00240.X  0.56
2004 Song ES, Juliano MA, Juliano L, Fried MG, Wagner SL, Hersh LB. ATP effects on insulin-degrading enzyme are mediated primarily through its triphosphate moiety. The Journal of Biological Chemistry. 279: 54216-20. PMID 15494400 DOI: 10.1074/Jbc.M411177200  0.56
2004 Huang J, Guan H, Booze RM, Eckman CB, Hersh LB. Estrogen regulates neprilysin activity in rat brain. Neuroscience Letters. 367: 85-7. PMID 15308303 DOI: 10.1016/J.Neulet.2004.05.085  0.56
2004 Cai Y, Cronin CN, Engel AG, Ohno K, Hersh LB, Rodgers DW. Choline acetyltransferase structure reveals distribution of mutations that cause motor Embo Journal. 23: 2047-2058. PMID 15131697 DOI: 10.1038/Sj.Emboj.7600221  0.56
2004 Shimojo M, Hersh LB. Regulation of the cholinergic gene locus by the repressor element-1 silencing transcription factor/neuron restrictive silencer factor (REST/NRSF). Life Sciences. 74: 2213-25. PMID 15017977 DOI: 10.1016/J.Lfs.2003.08.045  0.56
2004 Ma Z, Chow KM, Yao J, Hersh LB. Nuclear shuttling of the peptidase nardilysin. Archives of Biochemistry and Biophysics. 422: 153-60. PMID 14759602 DOI: 10.1016/J.Abb.2003.11.024  0.56
2004 Marr RA, Guan H, Rockenstein E, Kindy M, Gage FH, Verma I, Masliah E, Hersh LB. Neprilysin regulates amyloid Beta peptide levels. Journal of Molecular Neuroscience : Mn. 22: 5-11. PMID 14742905 DOI: 10.1385/Jmn:22:1-2:5  0.56
2003 Thompson MW, Hersh LB. Analysis of conserved residues of the human puromycin-sensitive aminopeptidase. Peptides. 24: 1359-65. PMID 14706550 DOI: 10.1016/J.Peptides.2003.07.012  0.56
2003 Shimojo M, Hersh LB. REST/NRSF-interacting LIM domain protein, a putative nuclear translocation receptor. Molecular and Cellular Biology. 23: 9025-31. PMID 14645515 DOI: 10.1128/Mcb.23.24.9025-9031.2003  0.56
2003 Song ES, Juliano MA, Juliano L, Hersh LB. Substrate activation of insulin-degrading enzyme (insulysin). A potential target for drug development. The Journal of Biological Chemistry. 278: 49789-94. PMID 14527953 DOI: 10.1074/Jbc.M308983200  0.32
2003 Wu CK, Nagykery N, Hersh LB, Scinto LFM, Geula C. Selective age-related loss of calbindin-D28k from basal forebrain cholinergic neurons in the common marmoset (callithrix jacchus) Neuroscience. 120: 249-259. PMID 12849757 DOI: 10.1016/S0306-4522(03)00248-3  0.56
2003 Miller BC, Eckman EA, Sambamurti K, Dobbs N, Chow KM, Eckman CB, Hersh LB, Thiele DL. Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo. Proceedings of the National Academy of Sciences of the United States of America. 100: 6221-6. PMID 12732730 DOI: 10.1073/Pnas.1031520100  0.56
2003 Thompson MW, Govindaswami M, Hersh LB. Mutation of active site residues of the puromycin-sensitive aminopeptidase: conversion of the enzyme into a catalytically inactive binding protein. Archives of Biochemistry and Biophysics. 413: 236-42. PMID 12729622 DOI: 10.1016/S0003-9861(03)00123-1  0.56
2003 Yamada ES, Dmitrieva N, Keyser KT, Lindstrom JM, Hersh LB, Marshak DW. Synaptic connections of starburst amacrine cells and localization of acetylcholine receptors in primate retinas. The Journal of Comparative Neurology. 461: 76-90. PMID 12722106 DOI: 10.1002/Cne.10672  0.56
2003 Kim MH, Lu M, Rogers G, Parsons S, Hersh LB. Specificity of the rat vesicular acetylcholine transporter. Neurochemical Research. 28: 473-6. PMID 12675133 DOI: 10.1023/A:1022804903088  0.56
2003 Marr RA, Rockenstein E, Mukherjee A, Kindy MS, Hersh LB, Gage FH, Verma IM, Masliah E. Neprilysin gene transfer reduces human amyloid pathology in transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1992-6. PMID 12657655 DOI: 10.1523/Jneurosci.23-06-01992.2003  0.56
2003 Hersh LB, Shimojo M. Regulation of cholinergic gene expression by the neuron restrictive silencer factor/repressor element-1 silencing transcription factor. Life Sciences. 72: 2021-8. PMID 12628452 DOI: 10.1016/S0024-3205(03)00065-1  0.56
2003 Chow KM, Oakley O, Goodman J, Ma Z, Juliano MA, Juliano L, Hersh LB. Nardilysin cleaves peptides at monobasic sites. Biochemistry. 42: 2239-44. PMID 12590613 DOI: 10.1021/Bi027178D  0.56
2002 Ma Z, Chow KM, Csuhai E, Hersh LB. The use of proteolysis to study the structure of nardilysin. Archives of Biochemistry and Biophysics. 401: 198-204. PMID 12054470 DOI: 10.1016/S0003-9861(02)00020-6  0.56
2002 Fischer HS, Zernig G, Hauser KF, Gerard C, Hersh LB, Saria A. Neutral endopeptidase knockout induces hyperalgesia in a model of visceral pain, an effect related to bradykinin and nitric oxide. Journal of Molecular Neuroscience : Mn. 18: 129-34. PMID 11931342 DOI: 10.1385/Jmn:18:1-2:129  0.56
2001 Shimojo M, Lee JH, Hersh LB. Role of zinc finger domains of the transcription factor neuron-restrictive silencer factor/repressor element-1 silencing transcription factor in DNA binding and nuclear localization. The Journal of Biological Chemistry. 276: 13121-6. PMID 11145971 DOI: 10.1074/Jbc.M011193200  0.56
2000 Shen R, Sumitomo M, Dai J, Hardy DO, Navarro D, Usmani B, Papandreou CN, Hersh LB, Shipp MA, Freedman LP, Nanus DM. Identification and characterization of two androgen response regions in the human neutral endopeptidase gene Molecular and Cellular Endocrinology. 170: 131-142. PMID 11162897 DOI: 10.1016/S0303-7207(00)00326-9  0.56
2000 Lian W, Chen G, Wu D, Brown CK, Madauss K, Hersh LB, Rodgers DW. Crystallization and preliminary analysis of neurolysin Acta Crystallographica Section D: Biological Crystallography. 56: 1644-1646. PMID 11092934 DOI: 10.1107/S0907444900012683  0.56
2000 Wu CK, Hersh LB, Geula C. Cyto- and chemoarchitecture of basal forebrain cholinergic neurons in the common marmoset (Callithrix jacchus) Experimental Neurology. 165: 306-326. PMID 10993691 DOI: 10.1006/Exnr.2000.7468  0.56
2000 Siems W, Maul B, Krause W, Gerard C, Hauser KF, Hersh LB, Fischer HS, Zernig G, Saria A. Neutral endopeptidase and alcohol consumption, experiments in neutral endopeptidase-deficient mice. European Journal of Pharmacology. 397: 327-34. PMID 10844131 DOI: 10.1016/S0014-2999(00)00222-3  0.56
2000 Cho GW, Kim MH, Chai YG, Gilmor ML, Levey AI, Hersh LB. Phosphorylation of the rat vesicular acetylcholine transporter. The Journal of Biological Chemistry. 275: 19942-8. PMID 10748073 DOI: 10.1074/Jbc.M902174199  0.56
1999 German DC, Manaye KF, Wu D, Hersh LB, Zweig RM. Mesopontine cholinergic and non-cholinergic neurons in schizophrenia. Neuroscience. 94: 33-8. PMID 10613494 DOI: 10.1016/S0306-4522(99)00305-X  0.56
1999 Holt DJ, Herman MM, Hyde TM, Kleinman JE, Sinton CM, German DC, Hersh LB, Graybiel AM, Saper CB. Evidence for a deficit in cholinergic interneurons in the striatum in schizophrenia. Neuroscience. 94: 21-31. PMID 10613493 DOI: 10.1016/S0306-4522(99)00279-1  0.56
1999 Shimojo M, Paquette AJ, Anderson DJ, Hersh LB. Protein kinase A regulates cholinergic gene expression in PC12 cells: REST4 silences the silencing activity of neuron-restrictive silencer factor/REST. Molecular and Cellular Biology. 19: 6788-95. PMID 10490617 DOI: 10.1128/Mcb.19.10.6788  0.56
1999 Gilmor ML, Erickson JD, Varoqui H, Hersh LB, Bennett DA, Cochran EJ, Mufson EJ, Levey AI. Preservation of nucleus basalis neurons containing choline acetyltransferase and the vesicular acetylcholine transporter in the elderly with mild cognitive impairment and early Alzheimer's disease. The Journal of Comparative Neurology. 411: 693-704. PMID 10421878 DOI: 10.1002/(Sici)1096-9861(19990906)411:4<693::Aid-Cne13>3.0.Co;2-D  0.56
1999 Thompson MW, Tobler A, Fontana A, Hersh LB. Cloning and analysis of the gene for the human puromycin-sensitive aminopeptidase. Biochemical and Biophysical Research Communications. 258: 234-40. PMID 10329370 DOI: 10.1006/Bbrc.1999.0604  0.56
1999 Manaye KF, Zweig R, Wu D, Hersh LB, De Lacalle S, Saper CB, German DC. Quantification of cholinergic and select non-cholinergic mesopontine neuronal populations in the human brain. Neuroscience. 89: 759-70. PMID 10199611 DOI: 10.1016/S0306-4522(98)00380-7  0.56
1999 Csuhai E, Juliano MA, Pyrek JS, Harms AC, Juliano L, Hersh LB. New fluorogenic substrates for N-arginine dibasic convertase Analytical Biochemistry. 269: 149-154. PMID 10094786 DOI: 10.1006/Abio.1999.4033  0.56
1998 Tanaka H, Shimojo M, Wu D, Hersh LB. Regulation of the cholinergic gene locus. Journal of Physiology, Paris. 92: 149-52. PMID 9782460 DOI: 10.1016/S0928-4257(98)80154-X  0.56
1998 Shimojo M, Wu D, Hersh LB. The cholinergic gene locus is coordinately regulated by protein kinase A II in PC12 cells. Journal of Neurochemistry. 71: 1118-26. PMID 9721736 DOI: 10.1046/J.1471-4159.1998.71031118.X  0.56
1998 Sarada B, Thiele D, Dang T, Lee J, Safavia A, Hersh LB, Cottam GL. Anti-CD3 activation of human CD4+ T cells increases expression of the intracellular β-endorphin endopeptidase (IDE/γ-EpGE) Journal of Neuroimmunology. 85: 59-68. PMID 9626998 DOI: 10.1016/S0165-5728(97)00268-3  0.56
1997 Saria A, Hauser KF, Traurig HH, Turbek CS, Hersh L, Gerard C. Opioid-related changes in nociceptive threshold and in tissue levels of enkephalins after target disruption of the gene for neutral endopeptidase (EC in mice. Neuroscience Letters. 234: 27-30. PMID 9347938 DOI: 10.1016/S0304-3940(97)00660-5  0.56
1996 Miller BC, Thiele D, Hersh LB, Cottam GL. A secreted peptidase involved in T cell β-endorphin metabolism Immunopharmacology. 31: 151-161. PMID 8861741 DOI: 10.1016/0162-3109(95)00046-1  0.56
1996 Holt DJ, Hersh LB, Saper CB. Cholinergic innervation in the human striatum: a three-compartment model. Neuroscience. 74: 67-87. PMID 8843078 DOI: 10.1016/0306-4522(96)00094-2  0.56
1996 Lian W, Wu D, Konings WN, Mierau I, Hersh LB. Heterologous expression and characterization of recombinant Lactococcus lactis neutral endopeptidase (neprilysin). Archives of Biochemistry and Biophysics. 333: 121-6. PMID 8806762 DOI: 10.1006/Abbi.1996.0372  0.56
1996 Li C, Booze RM, Hersh LB. Tissue-specific expression of rat neutral endopeptidase mRNAs. Annals of the New York Academy of Sciences. 780: 145-55. PMID 8602727 DOI: 10.1111/J.1749-6632.1996.Tb15118.X  0.56
1995 Li C, Booze RM, Hersh LB. Tissue-specific expression of rat neutral endopeptidase (neprilysin) mRNAs. The Journal of Biological Chemistry. 270: 5723-8. PMID 7890699 DOI: 10.1074/Jbc.270.11.5723  0.56
1995 Inoue H, Li YP, Wagner JA, Hersh LB. Expression of the choline acetyltransferase gene depends on protein kinase A activity Journal of Neurochemistry. 64: 985-990. PMID 7861180 DOI: 10.1046/J.1471-4159.1995.64030985.X  0.56
1995 Kioussi C, Mamalaki A, Jessen K, Mirsky R, Hersh LB, Matsas R. Expression of endopeptidase-24.11 (common acute lymphoblastic leukaemia antigen CD10) in the sciatic nerve of the adult rat after lesion and during regeneration. The European Journal of Neuroscience. 7: 951-61. PMID 7613630 DOI: 10.1111/J.1460-9568.1995.Tb01083.X  0.56
1995 Constam DB, Tobler AR, Rensing-Ehl A, Kemler I, Hersh LB, Fontana A. Puromycin-sensitive aminopeptidase: Sequence analysis, expression, and functional characterization Journal of Biological Chemistry. 270: 26931-26939. PMID 7592939 DOI: 10.1074/Jbc.270.45.26931  0.56
1994 Quay T, Slaughter C, Davis TP, Merrill BJ, Hersh LB. Positional effects in the neprilysin (neutral endopeptidase) reaction. Archives of Biochemistry and Biophysics. 308: 133-6. PMID 8311445 DOI: 10.1006/Abbi.1994.1019  0.56
1994 De Lacalle S, Lim C, Sobreviela T, Mufson EJ, Hersh LB, Saper CB. Cholinergic innervation in the human hippocampal formation including the entorhinal cortex. The Journal of Comparative Neurology. 345: 321-44. PMID 7929905 DOI: 10.1002/Cne.903450302  0.56
1994 Selden N, Geula C, Hersh L, Mesulam MM. Human striatum: chemoarchitecture of the caudate nucleus, putamen and ventral striatum in health and Alzheimer's disease. Neuroscience. 60: 621-36. PMID 7523983 DOI: 10.1016/0306-4522(94)90491-X  0.56
1993 de Lacalle S, Hersh LB, Saper CB. Cholinergic innervation of the human cerebellum. The Journal of Comparative Neurology. 328: 364-76. PMID 8440786 DOI: 10.1002/Cne.903280304  0.56
1993 Wu D, Schormann N, Lian W, Deisenhofer J, Hersh LB. Expression, purification, and characterization of recombinant Drosophila choline acetyltransferase. Journal of Neurochemistry. 61: 1416-22. PMID 8376995 DOI: 10.1111/J.1471-4159.1993.Tb13635.X  0.56
1993 Armstrong DM, Sheffield R, Buzsaki G, Chen KS, Hersh LB, Nearing B, Gage FH. Morphologic alterations of choline acetyltransferase-positive neurons in the basal forebrain of aged behaviorally characterized Fisher 344 rats. Neurobiology of Aging. 14: 457-70. PMID 8247228 DOI: 10.1016/0197-4580(93)90104-J  0.56
1992 Mesulam MM, Mash D, Hersh L, Bothwell M, Geula C. Cholinergic innervation of the human striatum, globus pallidus, subthalamic nucleus, substantia nigra, and red nucleus. The Journal of Comparative Neurology. 323: 252-68. PMID 1401259 DOI: 10.1002/Cne.903230209  0.56
1992 Mesulam MM, Hersh LB, Mash DC, Geula C. Differential cholinergic innervation within functional subdivisions of the human cerebral cortex: a choline acetyltransferase study. The Journal of Comparative Neurology. 318: 316-28. PMID 1374768 DOI: 10.1002/Cne.903180308  0.56
1991 Ibáñez CF, Pelto-Huikko M, Söder O, Ritzèn EM, Hersh LB, Hökfelt T, Persson H. Expression of choline acetyltransferase mRNA in spermatogenic cells results in an accumulation of the enzyme in the postacrosomal region of mature spermatozoa. Proceedings of the National Academy of Sciences of the United States of America. 88: 3676-80. PMID 2023918 DOI: 10.1073/Pnas.88.9.3676  0.56
1991 Armstrong DM, Brady R, Hersh LB, Hayes RC, Wiley RG. Expression of choline acetyltransferase and nerve growth factor receptor within hypoglossal motoneurons following nerve injury. The Journal of Comparative Neurology. 304: 596-607. PMID 1849521 DOI: 10.1002/Cne.903040407  0.56
1991 Fuxe K, Tinner B, Staines W, Hemsén A, Hersh L, Lundberg JM. Demonstration and nature of endothelin-3-like immunoreactivity in somatostatin and choline acetyltransferase-immunoreactive nerve cells of the neostriatum of the rat. Neuroscience Letters. 123: 107-11. PMID 1676496 DOI: 10.1016/0304-3940(91)90169-T  0.56
1990 Wang FZ, Nelson PG, Fitzgerald SC, Hersh LB, Neale EA. Cholinergic function in cultures of mouse spinal cord neurons. Journal of Neuroscience Research. 25: 312-23. PMID 2325157 DOI: 10.1002/Jnr.490250307  0.56
1990 Geula C, Tokuno H, Hersh L, Mesulam MM. Human striatal cholinergic neurons in development, aging and Alzheimer's disease. Brain Research. 508: 310-2. PMID 2306623 DOI: 10.1016/0006-8993(90)90414-7  0.56
1990 Johnson GD, Hersh LB. Studies on the subsite specificity of the rat brain puromycin-sensitive aminopeptidase Archives of Biochemistry and Biophysics. 276: 305-309. PMID 2306097 DOI: 10.1016/0003-9861(90)90724-D  0.56
1989 Alderson RF, Hua ZW, Hersh LB. Nerve growth factor and phorbol esters increase the number of choline acetyltransferase-positive cells in two morphologically distinct classes of basal forebrain neurons in primary cultures. Brain Research. Developmental Brain Research. 48: 229-41. PMID 2776295 DOI: 10.1016/0165-3806(89)90078-3  0.56
1989 Lysakowski A, Wainer BH, Bruce G, Hersh LB. An atlas of the regional and laminar distribution of choline acetyltransferase immunoreactivity in rat cerebral cortex. Neuroscience. 28: 291-336. PMID 2646551 DOI: 10.1016/0306-4522(89)90180-2  0.56
1989 Kordower JH, Gash DM, Bothwell M, Hersh L, Mufson EJ. Nerve growth factor receptor and choline acetyltransferase remain colocalized in the nucleus basalis (Ch4) of Alzheimer's patients. Neurobiology of Aging. 10: 67-74. PMID 2547171 DOI: 10.1016/S0197-4580(89)80013-2  0.56
1989 Mesulam MM, Geula C, Bothwell MA, Hersh LB. Human reticular formation: cholinergic neurons of the pedunculopontine and laterodorsal tegmental nuclei and some cytochemical comparisons to forebrain cholinergic neurons. The Journal of Comparative Neurology. 283: 611-33. PMID 2545747 DOI: 10.1002/Cne.902830414  0.56
1989 Hirsch EC, Graybiel AM, Hersh LB, Duyckaerts C, Agid Y. Striosomes and extrastriosomal matrix contain different amounts of immunoreactive choline acetyltransferase in the human striatum. Neuroscience Letters. 96: 145-50. PMID 2522606 DOI: 10.1016/0304-3940(89)90048-7  0.56
1989 Shipp MA, Vijayaraghavan J, Schmidt EV, Masteller EL, D'Adamio L, Hersh LB, Reinherz EL. Common acute lymphoblastic leukemia antigen (CALLA) is active neutral endopeptidase 24.11 ('enkephalinase'): Direct evidence by cDNA transfection analysis Proceedings of the National Academy of Sciences of the United States of America. 86: 297-301. PMID 2521388 DOI: 10.1073/Pnas.86.1.297  0.56
1988 Armstrong DM, Hersh LB, Gage FH. Morphologic alterations of cholinergic processes in the neocortex of aged rats. Neurobiology of Aging. 9: 199-205. PMID 3374737 DOI: 10.1016/S0197-4580(88)80051-4  0.56
1988 Armstrong DM, Rotler A, Hersh LB, Pickel VM. Localization of choline acetyltransferase in perikarya and dendrites within the nuclei of the solitary tracts. Journal of Neuroscience Research. 20: 279-90. PMID 3225867 DOI: 10.1002/Jnr.490200302  0.56
1988 Hersh LB, Takane K, Gylys K, Moomaw C, Slaughter C. Conservation of amino acid sequences between human and porcine choline acetyltransferase Journal of Neurochemistry. 51: 1843-1845. PMID 3183663 DOI: 10.1111/J.1471-4159.1988.Tb01166.X  0.56
1987 Armstrong DM, Bruce G, Hersh LB, Gage FH. Development of cholinergic neurons in the septal/diagonal band complex of the rat. Brain Research. 433: 249-56. PMID 3690335 DOI: 10.1016/0165-3806(87)90028-9  0.56
1987 Armstrong DM, Terry RD, Deteresa RM, Bruce G, Hersh LB, Gage FH. Response of septal cholinergic neurons to axotomy. The Journal of Comparative Neurology. 264: 421-36. PMID 3680637 DOI: 10.1002/Cne.902640309  0.56
1987 Shiromani PJ, Armstrong DM, Bruce G, Hersh LB, Groves PM, Gillin JC. Relation of pontine choline acetyltransferase immunoreactive neurons with cells which increase discharge during REM sleep. Brain Research Bulletin. 18: 447-55. PMID 3580914 DOI: 10.1016/0361-9230(87)90019-0  0.56
1986 Lysakowski A, Wainer BH, Rye DB, Bruce G, Hersh LB. Cholinergic innervation displays strikingly different laminar preferences in several cortical areas. Neuroscience Letters. 64: 102-8. PMID 3008035 DOI: 10.1016/0304-3940(86)90671-3  0.56
1986 Armstrong DM, Bruce G, Hersh LB, Terry RD. Choline acetyltransferase immunoreactivity in neuritic plaques of Alzheimer brain. Neuroscience Letters. 71: 229-34. PMID 2431362 DOI: 10.1016/0304-3940(86)90564-1  0.56
1985 Bruce G, Wainer BH, Hersh LB. Immunoaffinity purification of human choline acetyltransferase: comparison of the brain and placental enzymes. Journal of Neurochemistry. 45: 611-20. PMID 4009177 DOI: 10.1111/J.1471-4159.1985.Tb04030.X  0.56
1985 German DC, Bruce G, Hersh LB. Immunohistochemical staining of cholinergic neurons in the human brain using a polyclonal antibody to human choline acetyltransferase. Neuroscience Letters. 61: 1-5. PMID 3908999 DOI: 10.1016/0304-3940(85)90391-X  0.56
1985 Ojeda SR, Costa ME, Katz KH, Hersh LB. Evidence for the existence of substance P in the prepubertal rat ovary. I. Biochemical and physiologic studies. Biology of Reproduction. 33: 286-95. PMID 2412598 DOI: 10.1095/Biolreprod33.2.286  0.56
1980 Blumberg S, Teichberg VI, Charli JL, Hersh LB, McKelvy JF. Cleavage of substance P to an N-terminal tetrapeptide and a C-terminal heptapeptide by a post-proline Cleaving enzyme from bovine brain. Brain Research. 192: 477-86. PMID 6155176 DOI: 10.1016/0006-8993(80)90898-7  0.56
1978 Hersh LB, Coe B, Casey L. A fluorometric assay for choline acetyltransferase and its use in the purification of the enzyme from human placenta. Journal of Neurochemistry. 30: 1077-85. PMID 660185 DOI: 10.1111/J.1471-4159.1978.Tb12401.X  0.56
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