Year |
Citation |
Score |
2014 |
Xiao Y, Blumenthal K, Cummins TR. Gating-pore currents demonstrate selective and specific modulation of individual sodium channel voltage-sensors by biological toxins. Molecular Pharmacology. 86: 159-67. PMID 24898004 DOI: 10.1124/mol.114.092338 |
1 |
|
2010 |
Xiao Y, Blumenthal K, Jackson JO, Liang S, Cummins TR. The tarantula toxins ProTx-II and huwentoxin-IV differentially interact with human Nav1.7 voltage sensors to inhibit channel activation and inactivation. Molecular Pharmacology. 78: 1124-34. PMID 20855463 DOI: 10.1124/mol.110.066332 |
1 |
|
2010 |
Edgerton GB, Blumenthal KM, Hanck DA. Inhibition of the activation pathway of the T-type calcium channel Ca(V)3.1 by ProTxII. Toxicon : Official Journal of the International Society On Toxinology. 56: 624-36. PMID 20600227 DOI: 10.1016/j.toxicon.2010.06.009 |
1 |
|
2008 |
Edgerton GB, Blumenthal KM, Hanck DA. Evidence for multiple effects of ProTxII on activation gating in Na(V)1.5. Toxicon : Official Journal of the International Society On Toxinology. 52: 489-500. PMID 18657562 DOI: 10.1016/j.toxicon.2008.06.023 |
1 |
|
2008 |
Page B, Young R, Iyer V, Suzuki G, Lis M, Korotchkina L, Patel MS, Blumenthal KM, Fallavollita JA, Canty JM. Persistent regional downregulation in mitochondrial enzymes and upregulation of stress proteins in swine with chronic hibernating myocardium. Circulation Research. 102: 103-12. PMID 17967786 DOI: 10.1161/CIRCRESAHA.107.155895 |
1 |
|
2007 |
Smith JJ, Cummins TR, Alphy S, Blumenthal KM. Molecular interactions of the gating modifier toxin ProTx-II with NaV 1.5: implied existence of a novel toxin binding site coupled to activation. The Journal of Biological Chemistry. 282: 12687-97. PMID 17339321 DOI: 10.1074/jbc.M610462200 |
1 |
|
2007 |
Coling DE, Ding D, Young R, Lis M, Stofko E, Blumenthal KM, Salvi RJ. Proteomic analysis of cisplatin-induced cochlear damage: methods and early changes in protein expression. Hearing Research. 226: 140-56. PMID 17321087 DOI: 10.1016/j.heares.2006.12.017 |
1 |
|
2007 |
Smith JJ, Blumenthal KM. Site-3 sea anemone toxins: molecular probes of gating mechanisms in voltage-dependent sodium channels. Toxicon : Official Journal of the International Society On Toxinology. 49: 159-70. PMID 17095031 DOI: 10.1016/j.toxicon.2006.09.020 |
0.96 |
|
2007 |
Priest BT, Blumenthal KM, Smith JJ, Warren VA, Smith MM. ProTx-I and ProTx-II: gating modifiers of voltage-gated sodium channels. Toxicon : Official Journal of the International Society On Toxinology. 49: 194-201. PMID 17087985 DOI: 10.1016/j.toxicon.2006.09.014 |
0.96 |
|
2006 |
Kashlan OB, Maarouf AB, Kussius C, Denshaw RM, Blumenthal KM, Kleyman TR. Distinct structural elements in the first membrane-spanning segment of the epithelial sodium channel. The Journal of Biological Chemistry. 281: 30455-62. PMID 16912051 DOI: 10.1074/jbc.M604615200 |
1 |
|
2005 |
Smith JJ, Alphy S, Seibert AL, Blumenthal KM. Differential phospholipid binding by site 3 and site 4 toxins. Implications for structural variability between voltage-sensitive sodium channel domains. The Journal of Biological Chemistry. 280: 11127-33. PMID 15632158 DOI: 10.1074/jbc.M412552200 |
1 |
|
2004 |
Seibert AL, Liu J, Hanck DA, Blumenthal KM. Role of Asn-16 and Ser-19 in anthopleurin B binding. Implications for the electrostatic nature of Na(V) site 3. Biochemistry. 43: 7082-9. PMID 15170345 DOI: 10.1021/bi0496135 |
1 |
|
2003 |
Seibert AL, Liu J, Hanck DA, Blumenthal KM. Arg-14 loop of site 3 anemone toxins: effects of glycine replacement on toxin affinity. Biochemistry. 42: 14515-21. PMID 14661964 DOI: 10.1021/bi035291d |
1 |
|
2003 |
Blumenthal KM, Seibert AL. Voltage-gated sodium channel toxins: poisons, probes, and future promise. Cell Biochemistry and Biophysics. 38: 215-38. PMID 12777715 DOI: 10.1385/CBB:38:2:215 |
1 |
|
2000 |
Howell ML, Alsabbagh E, Ma JF, Ochsner UA, Klotz MG, Beveridge TJ, Blumenthal KM, Niederhoffer EC, Morris RE, Needham D, Dean GE, Wani MA, Hassett DJ. AnkB, a periplasmic ankyrin-like protein in Pseudomonas aeruginosa, is required for optimal catalase B (KatB) activity and resistance to hydrogen peroxide Journal of Bacteriology. 182: 4545-4556. PMID 10913088 DOI: 10.1128/JB.182.16.4545-4556.2000 |
1 |
|
1998 |
Benzinger GR, Kyle JW, Blumenthal KM, Hanck DA. A specific interaction between the cardiac sodium channel and site-3 toxin anthopleurin B Journal of Biological Chemistry. 273: 80-84. PMID 9417050 DOI: 10.1074/jbc.273.1.80 |
1 |
|
1996 |
Kelso GJ, Drum CL, Hanck DA, Blumenthal KM. Role for Pro-13 in directing high-affinity binding of anthopleurin B to the voltage-sensitive sodium channel Biochemistry. 35: 14157-14164. PMID 8916901 DOI: 10.1021/bi961584d |
1 |
|
1996 |
Dias-Kadambi BL, Combs KA, Drum CL, Hanck DA, Blumenthal KM. The role of exposed tryptophan residues in the activity of the cardiotonic polypeptide anthopleurin B Journal of Biological Chemistry. 271: 23828-23835. PMID 8798612 DOI: 10.1074/jbc.271.39.23828 |
1 |
|
1996 |
Dias-Kadambi BL, Drum CL, Hanck DA, Blumenthal KM. Leucine 18, a hydrophobic residue essential for high affinity binding of anthopleurin B to the voltage-sensitive sodium channel Journal of Biological Chemistry. 271: 9422-9428. PMID 8621610 DOI: 10.1074/jbc.271.16.9422 |
1 |
|
1995 |
Khera PK, Benzinger GR, Lipkind G, Drum CL, Hanck DA, Blumenthal KM. Multiple cationic residues of anthopleurin B that determine high affinity and channel isoform discrimination Biochemistry. 34: 8533-8541. PMID 7612595 DOI: 10.1021/bi00027a003 |
1 |
|
1986 |
Lieberman DL, Blumenthal KM. Structure and action of heteronemertine polypeptide toxins. Specific cross-linking of Cerebratulus lacteus toxin B-IV to lobster axon membrane vesicles. Biochimica Et Biophysica Acta. 855: 41-8. PMID 3942745 DOI: 10.1016/0005-2736(86)90186-0 |
1 |
|
1980 |
Blumenthal KM, Kem WR. Structure and action of heteronemertine polypeptide toxins: inactivation of Cerebratulus lacteus toxin B-IV by tyrosine nitration. Archives of Biochemistry and Biophysics. 203: 816-21. PMID 7458356 DOI: 10.1016/0003-9861(80)90243-X |
1 |
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