Year |
Citation |
Score |
2022 |
Hayter EA, Azibere S, Skrajewski LA, Soule LD, Spence DM, Martin RS. A 3D-printed, multi-modal microfluidic device for measuring nitric oxide and ATP release from flowing red blood cells. Analytical Methods : Advancing Methods and Applications. PMID 35959771 DOI: 10.1039/d2ay00931e |
0.386 |
|
2022 |
Liu Y, Hesse LE, Geiger MK, Zinn KR, McMahon TJ, Chen C, Spence DM. A 3D-printed transfusion platform reveals beneficial effects of normoglycemic erythrocyte storage solutions and a novel rejuvenating solution. Lab On a Chip. PMID 35258064 DOI: 10.1039/d2lc00030j |
0.345 |
|
2020 |
Jacobs MJ, Pinger CW, Castiaux AD, Maloney KJ, Spence DM. A novel 3D-printed centrifugal ultrafiltration method reveals in vivo glycation of human serum albumin decreases its binding affinity for zinc. Metallomics : Integrated Biometal Science. PMID 32626857 DOI: 10.1039/D0Mt00123F |
0.306 |
|
2020 |
Geiger M, Zinn K, Spence D. Investigating the Binding of Albumin and C‐peptide to Red Blood Cells The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05337 |
0.324 |
|
2019 |
Castiaux AD, Spence DM, Martin RS. Review of 3D Cell Culture with Analysis in Microfluidic Systems. Analytical Methods : Advancing Methods and Applications. 11: 4220-4232. PMID 32051693 DOI: 10.1039/C9Ay01328H |
0.328 |
|
2019 |
Castiaux AD, Pinger C, Hayter EA, Bunn ME, Martin RS, Spence DM. PolyJet 3D-Printed Enclosed Microfluidic Channels without Photocurable Supports. Analytical Chemistry. PMID 31035747 DOI: 10.1021/Acs.Analchem.9B01302 |
0.36 |
|
2018 |
Heller AA, Lockwood SY, Janes TM, Spence DM. Technologies for Measuring Pharmacokinetic Profiles. Annual Review of Analytical Chemistry (Palo Alto, Calif.). PMID 29324183 DOI: 10.1146/Annurev-Anchem-061417-125611 |
0.724 |
|
2018 |
Janes T, Spence DM. Steroid inhibition of erythrocyte-derived ATP reduces endothelial cell production of nitric oxide in a 3D-printed fluidic model Analytical Methods. 10: 3416-3422. DOI: 10.1039/C8Ay00870A |
0.377 |
|
2018 |
Pinger CW, Castiaux A, Speed S, Spence DM. Plate Reader Compatible 3D-Printed Device for Teaching Equilibrium Dialysis Binding Assays Journal of Chemical Education. 95: 1662-1667. DOI: 10.1021/Acs.Jchemed.8B00215 |
0.316 |
|
2017 |
Pinger C, Heller A, Spence DM. A Printed Equilibrium-Dialysis Device with Integrated Membranes for Improved Binding Affinity Measurements. Analytical Chemistry. PMID 28648046 DOI: 10.1021/Acs.Analchem.7B01848 |
0.331 |
|
2017 |
Gross B, Lockwood SY, Spence DM. Recent Advances in Analytical Chemistry by 3D Printing. Analytical Chemistry. 89: 57-70. PMID 28105825 DOI: 10.1021/Acs.Analchem.6B04344 |
0.71 |
|
2016 |
Chen C, Mehl BT, Munshi AS, Townsend AD, Spence DM, Martin RS. 3D-printed Microfluidic Devices: Fabrication, Advantages and Limitations-a Mini Review. Analytical Methods : Advancing Methods and Applications. 8: 6005-6012. PMID 27617038 DOI: 10.1039/C6Ay01671E |
0.332 |
|
2016 |
Lockwood SY, Summers S, Eggenberger E, Spence DM. An In Vitro Diagnostic for Multiple Sclerosis Based on C-peptide Binding to Erythrocytes. Ebiomedicine. PMID 27528268 DOI: 10.1016/J.Ebiom.2016.07.036 |
0.733 |
|
2016 |
LaBonia GJ, Lockwood SY, Heller AA, Spence DM, Hummon AB. Drug penetration and metabolism in 3-dimensional cell cultures treated in a 3D printed fluidic device: Assessment of irinotecan via MALDI imaging mass spectrometry. Proteomics. PMID 27198560 DOI: 10.1002/Pmic.201500524 |
0.749 |
|
2016 |
Lockwood SY, Meisel JE, Monsma FJ, Spence DM. A Diffusion-Based and Dynamic 3D-Printed Device That Enables Parallel in Vitro Pharmacokinetic Profiling of Molecules. Analytical Chemistry. PMID 26727249 DOI: 10.1021/Acs.Analchem.5B04270 |
0.756 |
|
2016 |
Mu R, Chen C, Wang Y, Spence DM. A quantitative, in vitro appraisal of experimental low-glucose storage solutions used for blood banking Analytical Methods. 8: 6856-6864. DOI: 10.1039/C6Ay02128J |
0.338 |
|
2015 |
Gross BC, Anderson KB, Meisel JE, McNitt MI, Spence DM. Polymer Coatings in 3D-Printed Fluidic Device Channels for Improved Cellular Adherence Prior to Electrical Lysis. Analytical Chemistry. 87: 6335-41. PMID 25973637 DOI: 10.1021/Acs.Analchem.5B01202 |
0.639 |
|
2015 |
Liu Y, Chen C, Summers S, Medawala W, Spence DM. C-peptide and zinc delivery to erythrocytes requires the presence of albumin: implications in diabetes explored with a 3D-printed fluidic device. Integrative Biology : Quantitative Biosciences From Nano to Macro. 7: 534-43. PMID 25825241 DOI: 10.1039/C4Ib00243A |
0.346 |
|
2014 |
Selimovic A, Erkal JL, Spence DM, Martin RS. Microfluidic device with tunable post arrays and integrated electrodes for studying cellular release. The Analyst. 139: 5686-94. PMID 25105251 DOI: 10.1039/C4An01062K |
0.409 |
|
2014 |
Erkal JL, Selimovic A, Gross BC, Lockwood SY, Walton EL, McNamara S, Martin RS, Spence DM. 3D printed microfluidic devices with integrated versatile and reusable electrodes. Lab On a Chip. 14: 2023-32. PMID 24763966 DOI: 10.1039/C4Lc00171K |
0.757 |
|
2014 |
Chen C, Wang Y, Lockwood SY, Spence DM. 3D-printed fluidic devices enable quantitative evaluation of blood components in modified storage solutions for use in transfusion medicine. The Analyst. 139: 3219-26. PMID 24660218 DOI: 10.1039/C3An02357E |
0.754 |
|
2014 |
Lockwood SY, Erkal JL, Spence DM. Endothelium-derived nitric oxide production is increased by ATP released from red blood cells incubated with hydroxyurea. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 38: 1-7. PMID 24530476 DOI: 10.1016/J.Niox.2014.02.003 |
0.809 |
|
2014 |
Gross BC, Erkal JL, Lockwood SY, Chen C, Spence DM. Evaluation of 3D printing and its potential impact on biotechnology and the chemical sciences. Analytical Chemistry. 86: 3240-53. PMID 24432804 DOI: 10.1021/Ac403397R |
0.711 |
|
2014 |
Wang Y, Giebink A, Spence DM. Microfluidic evaluation of red cells collected and stored in modified processing solutions used in blood banking. Integrative Biology : Quantitative Biosciences From Nano to Macro. 6: 65-75. PMID 24292633 DOI: 10.1039/C3Ib40187A |
0.788 |
|
2013 |
Anderson KB, Lockwood SY, Martin RS, Spence DM. A 3D printed fluidic device that enables integrated features. Analytical Chemistry. 85: 5622-6. PMID 23687961 DOI: 10.1021/Ac4009594 |
0.791 |
|
2013 |
Anderson KB, Halpin ST, Johnson AS, Martin RS, Spence DM. Integration of multiple components in polystyrene-based microfluidic devices part II: cellular analysis. The Analyst. 138: 137-43. PMID 23120748 DOI: 10.1039/C2An36171J |
0.816 |
|
2013 |
Johnson AS, Anderson KB, Halpin ST, Kirkpatrick DC, Spence DM, Martin RS. Integration of multiple components in polystyrene-based microfluidic devices part I: fabrication and characterization. The Analyst. 138: 129-36. PMID 23120747 DOI: 10.1039/C2An36168J |
0.783 |
|
2013 |
Giebink AW, Vogel PA, Medawala W, Spence DM. C-peptide-stimulated nitric oxide production in a cultured pulmonary artery endothelium is erythrocyte mediated and requires Zn(2+). Diabetes/Metabolism Research and Reviews. 29: 44-52. PMID 23007928 DOI: 10.1002/Dmrr.2359 |
0.768 |
|
2012 |
Anderson KB, Karunarathne W, Spence DM. Measuring P2X1 receptor activity in washed platelets in the absence of exogenous apyrase Analytical Methods. 4: 101-105. DOI: 10.1039/C1Ay05530E |
0.783 |
|
2011 |
Vogel PA, Halpin ST, Martin RS, Spence DM. Microfluidic transendothelial electrical resistance measurement device that enables blood flow and postgrowth experiments. Analytical Chemistry. 83: 4296-301. PMID 21513343 DOI: 10.1021/Ac2004746 |
0.771 |
|
2010 |
Halpin ST, Spence DM. Direct plate-reader measurement of nitric oxide released from hypoxic erythrocytes flowing through a microfluidic device. Analytical Chemistry. 82: 7492-7. PMID 20681630 DOI: 10.1021/Ac101130S |
0.785 |
|
2010 |
Raththagala M, Karunarathne W, Kryziniak M, McCracken J, Spence DM. Hydroxyurea stimulates the release of ATP from rabbit erythrocytes through an increase in calcium and nitric oxide production European Journal of Pharmacology. 645: 32-38. PMID 20655902 DOI: 10.1016/J.Ejphar.2010.07.012 |
0.81 |
|
2010 |
Letourneau S, Hernandez L, Faris AN, Spence DM. Evaluating the effects of estradiol on endothelial nitric oxide stimulated by erythrocyte-derived ATP using a microfluidic approach. Analytical and Bioanalytical Chemistry. 397: 3369-75. PMID 20393839 DOI: 10.1007/S00216-010-3687-7 |
0.811 |
|
2010 |
Keltner Z, Meyer JA, Johnson EM, Palumbo AM, Spence DM, Reid GE. Mass spectrometric characterization and activity of zinc-activated proinsulin C-peptide and C-peptide mutants. The Analyst. 135: 278-88. PMID 20098759 DOI: 10.1039/B917600D |
0.516 |
|
2010 |
Tolan NV, Meyer JA, Ku CJ, Karunarathne W, Spence DM. Use of the red blood cell as a simple drug target and diagnostic by manipulating and monitoring its ability to release adenosine triphosphate (ATP) Pure and Applied Chemistry. 82: 1623-1634. DOI: 10.1351/Pac-Con-10-02-10 |
0.793 |
|
2009 |
Medawala W, McCahill P, Giebink A, Meyer J, Ku CJ, Spence DM. A Molecular Level Understanding of Zinc Activation of C-peptide and its Effects on Cellular Communication in the Bloodstream. The Review of Diabetic Studies : Rds. 6: 148-58. PMID 20039004 DOI: 10.1900/RDS.2009.6.148 |
0.778 |
|
2009 |
Karunarathne W, Ku CJ, Spence DM. The dual nature of extracellular ATP as a concentration-dependent platelet P2X1 agonist and antagonist. Integrative Biology : Quantitative Biosciences From Nano to Macro. 1: 655-63. PMID 20027374 DOI: 10.1039/B909873A |
0.67 |
|
2009 |
Meyer JA, Subasinghe W, Sima AA, Keltner Z, Reid GE, Daleke D, Spence DM. Zinc-activated C-peptide resistance to the type 2 diabetic erythrocyte is associated with hyperglycemia-induced phosphatidylserine externalization and reversed by metformin. Molecular Biosystems. 5: 1157-62. PMID 19756305 DOI: 10.1039/B908241G |
0.543 |
|
2009 |
Tolan NV, Genes LI, Subasinghe W, Raththagala M, Spence DM. Personalized metabolic assessment of erythrocytes using microfluidic delivery to an array of luminescent wells. Analytical Chemistry. 81: 3102-8. PMID 19301907 DOI: 10.1021/Ac900084G |
0.808 |
|
2009 |
Oblak TD, Meyer JA, Spence DM. A microfluidic technique for monitoring bloodstream analytes indicative of C-peptide resistance in type 2 diabetes. The Analyst. 134: 188-93. PMID 19082192 DOI: 10.1039/B816740K |
0.581 |
|
2008 |
Tolan NV, Genes LI, Spence DM. Merging Microfluidics with Micro-titre Technology for More Efficient Drug Discovery. Jala (Charlottesville, Va.). 13: 275-279. PMID 21113418 DOI: 10.1016/J.Jala.2008.05.002 |
0.713 |
|
2008 |
Ku CJ, D'Amico Oblak T, Spence DM. Interactions between multiple cell types in parallel microfluidic channels: monitoring platelet adhesion to an endothelium in the presence of an anti-adhesion drug. Analytical Chemistry. 80: 7543-8. PMID 18729474 DOI: 10.1021/Ac801114J |
0.779 |
|
2008 |
Subasinghe W, Spence DM. Simultaneous determination of cell aging and ATP release from erythrocytes and its implications in type 2 diabetes. Analytica Chimica Acta. 618: 227-33. PMID 18513544 DOI: 10.1016/J.Aca.2008.04.061 |
0.473 |
|
2008 |
Faris A, Spence DM. Measuring the simultaneous effects of hypoxia and deformation on ATP release from erythrocytes. The Analyst. 133: 678-82. PMID 18427692 DOI: 10.1039/B719990B |
0.79 |
|
2008 |
Meyer JA, Froelich JM, Reid GE, Karunarathne WK, Spence DM. Metal-activated C-peptide facilitates glucose clearance and the release of a nitric oxide stimulus via the GLUT1 transporter. Diabetologia. 51: 175-82. PMID 17965850 DOI: 10.1007/S00125-007-0853-3 |
0.801 |
|
2007 |
Hulvey MK, Genes LI, Spence DM, Martin RS. Fabrication and evaluation of a 3-dimensional microchip device where carbon microelectrodes individually address channels in the separate fluidic layers. The Analyst. 132: 1246-53. PMID 18318286 DOI: 10.1039/B711148G |
0.373 |
|
2007 |
Genes LI, V Tolan N, Hulvey MK, Martin RS, Spence DM. Addressing a vascular endothelium array with blood components using underlying microfluidic channels. Lab On a Chip. 7: 1256-9. PMID 17896007 DOI: 10.1039/B712619K |
0.373 |
|
2007 |
Carroll JS, Ku CJ, Karunarathne W, Spence DM. Red blood cell stimulation of platelet nitric oxide production indicated by quantitative monitoring of the communication between cells in the bloodstream. Analytical Chemistry. 79: 5133-8. PMID 17580956 DOI: 10.1021/Ac0706271 |
0.818 |
|
2007 |
Ku CJ, Karunarathne W, Kenyon S, Root P, Spence D. Fluorescence determination of nitric oxide production in stimulated and activated platelets. Analytical Chemistry. 79: 2421-6. PMID 17288406 DOI: 10.1021/Ac061572Q |
0.8 |
|
2006 |
Raththagala M, Root PD, Spence DM. Dynamic monitoring of glutathione in erythrocytes, without a separation step, in the presence of an oxidant insult. Analytical Chemistry. 78: 8556-60. PMID 17165853 DOI: 10.1021/Ac061163U |
0.776 |
|
2006 |
Martin RS, Root PD, Spence DM. Microfluidic technologies as platforms for performing quantitative cellular analyses in an in vitro environment. The Analyst. 131: 1197-206. PMID 17066186 DOI: 10.1039/B611041J |
0.352 |
|
2006 |
Carroll J, Raththagala M, Subasinghe W, Baguzis S, D'amico Oblak T, Root P, Spence D. An altered oxidant defense system in red blood cells affects their ability to release nitric oxide-stimulating ATP. Molecular Biosystems. 2: 305-11. PMID 16880949 DOI: 10.1039/B604362N |
0.777 |
|
2006 |
D'Amico Oblak T, Root P, Spence DM. Fluorescence monitoring of ATP-stimulated, endothelium-derived nitric oxide production in channels of a poly(dimethylsiloxane)-based microfluidic device. Analytical Chemistry. 78: 3193-7. PMID 16643013 DOI: 10.1021/Ac052066O |
0.791 |
|
2006 |
Price AK, Martin RS, Spence DM. Monitoring erythrocytes in a microchip channel that narrows uniformly: towards an improved microfluidic-based mimic of the microcirculation. Journal of Chromatography. A. 1111: 220-7. PMID 16569581 DOI: 10.1016/J.Chroma.2005.07.083 |
0.407 |
|
2006 |
Spence DM, Meyer JA. Release of Erythrocyte-Derived ATP, a Recognized Stimulus of Nitric Oxide Production, Is Increased upon Incubation of Erythrocytes with C-Peptide. Blood. 108: 1567-1567. DOI: 10.1182/Blood.V108.11.1567.1567 |
0.458 |
|
2005 |
SPENCE D. Automation and Microfluidic Assays: In Vitro Models of the Mammalian Microcirculation Journal of the Association For Laboratory Automation. 10: 270-275. DOI: 10.1016/J.Jala.2005.06.006 |
0.3 |
|
2005 |
Li MW, Spence DM, Martin RS. A microchip-based system for immobilizing PC 12 cells and amperometrically detecting catecholamines released after stimulation with calcium Electroanalysis. 17: 1171-1180. DOI: 10.1002/Elan.200403231 |
0.381 |
|
2004 |
Spence DM, Torrence NJ, Kovarik ML, Martin RS. Amperometric determination of nitric oxide derived from pulmonary artery endothelial cells immobilized in a microchip channel. The Analyst. 129: 995-1000. PMID 15508026 DOI: 10.1039/B410547H |
0.408 |
|
2004 |
Price AK, Fischer DJ, Martin RS, Spence DM. Deformation-induced release of ATP from erythrocytes in a poly(dimethylsiloxane)-based microchip with channels that mimic resistance vessels. Analytical Chemistry. 76: 4849-55. PMID 15307797 DOI: 10.1021/Ac0495992 |
0.419 |
|
2003 |
Fischer DJ, Torrence NJ, Sprung RJ, Spence DM. Determination of erythrocyte deformability and its correlation to cellular ATP release using microbore tubing with diameters that approximate resistance vessels in vivo. The Analyst. 128: 1163-8. PMID 14529024 DOI: 10.1039/B308225N |
0.34 |
|
2003 |
Gordito MP, Kotsis DH, Minteer SD, Spence DM. Flow-based amperometric detection of dopamine in an immobilized cell reactor. Journal of Neuroscience Methods. 124: 129-34. PMID 12706842 DOI: 10.1016/S0165-0270(02)00383-7 |
0.345 |
|
2003 |
Sprague RS, Olearczyk JJ, Spence DM, Stephenson AH, Sprung RW, Lonigro AJ. Extracellular ATP signaling in the rabbit lung: erythrocytes as determinants of vascular resistance. American Journal of Physiology. Heart and Circulatory Physiology. 285: H693-700. PMID 12689860 DOI: 10.1152/Ajpheart.01026.2002 |
0.39 |
|
2003 |
Kotsis DH, Spence DM. Detection of ATP-induced nitric oxide in a biomimetic circulatory vessel containing an immobilized endothelium. Analytical Chemistry. 75: 145-51. PMID 12530831 DOI: 10.1021/Ac0258249 |
0.442 |
|
2002 |
Sprung R, Sprague R, Spence D. Determination of ATP release from erythrocytes using microbore tubing as a model of resistance vessels in vivo. Analytical Chemistry. 74: 2274-8. PMID 12038751 DOI: 10.1021/Ac011144E |
0.427 |
|
2001 |
Edwards J, Sprung R, Sprague R, Spence D. Chemiluminescence detection of ATP release from red blood cells upon passage through microbore tubing. The Analyst. 126: 1257-60. PMID 11534589 DOI: 10.1039/B100519G |
0.469 |
|
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