Jun Nakamura - Publications

Affiliations: 
Environmental Sciences & Engineering University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Environmental Sciences, Molecular Biology, Toxicology

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Nakamura J. Potential doxorubicin-mediated dual-targeting chemotherapy in FANC/BRCA-deficient tumors via modulation of cellular formaldehyde concentration. Chemical Research in Toxicology. PMID 32876438 DOI: 10.1021/acs.chemrestox.0c00288  0.337
2020 Nakamura J, Holley DW, Kawamoto T, Bultman SJ. The failure of two major formaldehyde catabolism enzymes (ADH5 and ALDH2) leads to partial synthetic lethality in C57BL/6 mice. Genes and Environment : the Official Journal of the Japanese Environmental Mutagen Society. 42: 21. PMID 32514323 DOI: 10.1186/S41021-020-00160-4  0.413
2020 Nakamura J, Nakamura M. DNA-protein crosslink formation by endogenous aldehydes and AP sites. Dna Repair. 88: 102806. PMID 32070903 DOI: 10.1016/j.dnarep.2020.102806  0.327
2019 Ridpath JR, Nakamura J. Acid-specific formaldehyde donor is a potential, dual targeting cancer chemotherapeutic/chemo preventive drug for FANC/BRCA-mutant cancer. Genes and Environment : the Official Journal of the Japanese Environmental Mutagen Society. 41: 23. PMID 31890056 DOI: 10.1186/S41021-019-0136-5  0.734
2018 Saha LK, Kim S, Kang H, Akter S, Choi K, Sakuma T, Yamamoto T, Sasanuma H, Hirota K, Nakamura J, Honma M, Takeda S, Dertinger S. Differential micronucleus frequency in isogenic human cells deficient in DNA repair pathways is a valuable indicator for evaluating genotoxic agents and their genotoxic mechanisms. Environmental and Molecular Mutagenesis. PMID 29761828 DOI: 10.1002/Em.22201  0.374
2017 Tsuda M, Cho K, Ooka M, Shimizu N, Watanabe R, Yasui A, Nakazawa Y, Ogi T, Harada H, Agama K, Nakamura J, Asada R, Fujiike H, Sakuma T, Yamamoto T, et al. ALC1/CHD1L, a chromatin-remodeling enzyme, is required for efficient base excision repair. Plos One. 12: e0188320. PMID 29149203 DOI: 10.1371/Journal.Pone.0188320  0.47
2017 De La Rosa VY, Asfaha J, Fasullo M, Loguinov A, Li P, Moore LE, Rothman N, Nakamura J, Swenberg J, Scelo G, Zhang L, Smith MT, Vulpe CD. High throughput functional genomics identifies modulators of TCE metabolite genotoxicity and candidate susceptibility genes. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28973557 DOI: 10.1093/Toxsci/Kfx159  0.432
2016 Tian X, Patel K, Ridpath JR, Chen Y, Zhou YH, Neo D, Clement J, Takata M, Takeda S, Sale J, Wright FA, Swenberg JA, Nakamura J. Homologous Recombination and Translesion DNA Synthesis Play Critical Roles on Tolerating DNA Damage Caused by Trace Levels of Hexavalent Chromium. Plos One. 11: e0167503. PMID 27907204 DOI: 10.1371/Journal.Pone.0167503  0.779
2016 Hashimoto K, Sharma V, Sasanuma H, Tian X, Takata M, Takeda S, Swenberg JA, Nakamura J. Poor recognition of O6-isopropyl dG by MGMT triggers double strand break-mediated cell death and micronucleus induction in FANC-deficient cells. Oncotarget. PMID 27486975 DOI: 10.18632/Oncotarget.10928  0.456
2016 Sharma V, Collins LB, Chen TH, Herr N, Takeda S, Sun W, Swenberg JA, Nakamura J. Oxidative stress at low levels can induce clustered DNA lesions leading to NHEJ mediated mutations. Oncotarget. PMID 27015367 DOI: 10.18632/Oncotarget.8298  0.451
2015 Hashimoto K, Takeda S, Swenberg JA, Nakamura J. Incorporation of metabolic activation potentiates cyclophosphamide-induced DNA damage response in isogenic DT40 mutant cells. Mutagenesis. 30: 821-8. PMID 26085549 DOI: 10.1093/Mutage/Gev042  0.44
2015 Hirota K, Yoshikiyo K, Guilbaud G, Tsurimoto T, Murai J, Tsuda M, Phillips LG, Narita T, Nishihara K, Kobayashi K, Yamada K, Nakamura J, Pommier Y, Lehmann A, Sale JE, et al. The POLD3 subunit of DNA polymerase δ can promote translesion synthesis independently of DNA polymerase ζ. Nucleic Acids Research. 43: 1671-83. PMID 25628356 DOI: 10.1093/Nar/Gkv023  0.449
2015 Smith-Roe SL, Nakamura J, Holley D, Chastain PD, Rosson GB, Simpson DA, Ridpath JR, Kaufman DG, Kaufmann WK, Bultman SJ. SWI/SNF complexes are required for full activation of the DNA-damage response. Oncotarget. 6: 732-45. PMID 25544751 DOI: 10.18632/Oncotarget.2715  0.766
2014 Nakamura J, Mutlu E, Sharma V, Collins L, Bodnar W, Yu R, Lai Y, Moeller B, Lu K, Swenberg J. The endogenous exposome. Dna Repair. 19: 3-13. PMID 24767943 DOI: 10.1016/J.Dnarep.2014.03.031  0.403
2014 Sharma V, Collins LB, Clement JM, Zhang Z, Nakamura J, Swenberg JA. Molecular dosimetry of endogenous and exogenous O(6)-methyl-dG and N7-methyl-G adducts following low dose [D3]-methylnitrosourea exposures in cultured human cells. Chemical Research in Toxicology. 27: 480-2. PMID 24628573 DOI: 10.1021/Tx5000602  0.32
2014 Tian X, Patel K, Ridpath JR, Swenberg JA, Nakamura J. Abstract 5363: Genotoxicity of trace level of hexavalent chromium existing in city water Cancer Research. 74: 5363-5363. DOI: 10.1158/1538-7445.Am2014-5363  0.744
2014 Nakamura J, Tian X. Abstract 2410: Crucial role of the non-BRCT automodification domain of PARP1 in either DNA binding and PARP inhibitor-mediated cell toxicity Cancer Research. 74: 2410-2410. DOI: 10.1158/1538-7445.Am2014-2410  0.427
2013 Hira A, Yabe H, Yoshida K, Okuno Y, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Nakamura J, Kojima S, Ogawa S, Matsuo K, Takata M, Yabe M. Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients. Blood. 122: 3206-9. PMID 24037726 DOI: 10.1182/Blood-2013-06-507962  0.355
2013 Pachkowski B, Nakamura J. A neutral glyoxal gel electrophoresis method for the detection and semi-quantitation of DNA single-strand breaks. Methods in Molecular Biology (Clifton, N.J.). 1054: 133-43. PMID 23913289 DOI: 10.1007/978-1-62703-565-1_8  0.422
2013 Nakamura J, Tian X, Swenberg J. Abstract LB-151: REV1 has critical roles in base excision repair intermediate-mediated transversion mutations but not for O6-methylguanine-initiated mutations in vertebrate cells. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-151  0.412
2013 Clement J, Nakamura J. Abstract 4486: 5-Hydroxymethyl-2’-deoxyuridine, but not temozolomide, enhances the selective synthetic lethality in BRCA1 and BRCA2-deficient cells caused by PARP inhibition. Cancer Research. 73: 4486-4486. DOI: 10.1158/1538-7445.Am2013-4486  0.47
2013 Tian X, Swenberg J, Nakamura J. Abstract 1281: POLD3 is required for DNA damage response to endogenous and exogenous DNA damage in human cells. Cancer Research. 73: 1281-1281. DOI: 10.1158/1538-7445.Am2013-1281  0.495
2012 Luke AM, Nakamura J. O-hydroxylamine-coupled alkaline gel electrophoresis assay for the detection and measurement of DNA single-strand breaks. Methods in Molecular Biology (Clifton, N.J.). 920: 307-13. PMID 22941612 DOI: 10.1007/978-1-61779-998-3_21  0.399
2012 Hu J, Nakamura J, Richardson SD, Aitken MD. Evaluating the effects of bioremediation on genotoxicity of polycyclic aromatic hydrocarbon-contaminated soil using genetically engineered, higher eukaryotic cell lines. Environmental Science & Technology. 46: 4607-13. PMID 22443351 DOI: 10.1021/Es300020E  0.337
2012 Nakamura J, Gul H, Tian X, Bultman SJ, Swenberg JA. Detection of PIGO-deficient cells using proaerolysin: a valuable tool to investigate mechanisms of mutagenesis in the DT40 cell system. Plos One. 7: e33563. PMID 22428069 DOI: 10.1371/Journal.Pone.0033563  0.397
2012 Lu K, Craft S, Nakamura J, Moeller BC, Swenberg JA. Use of LC-MS/MS and stable isotopes to differentiate hydroxymethyl and methyl DNA adducts from formaldehyde and nitrosodimethylamine. Chemical Research in Toxicology. 25: 664-75. PMID 22148432 DOI: 10.1021/Tx200426B  0.409
2012 Nakamura J, Tian X, Bultman S, Swenberg JA. Abstract 2552: Detection of PIGO-deficient cells using proaerolysin: a valuable tool to investigate mechanisms of mutagenesis in the DT40 cell system Cancer Research. 72: 2552-2552. DOI: 10.1158/1538-7445.Am2012-2552  0.443
2011 Swenberg JA, Lu K, Moeller BC, Gao L, Upton PB, Nakamura J, Starr TB. Endogenous versus exogenous DNA adducts: their role in carcinogenesis, epidemiology, and risk assessment. Toxicological Sciences : An Official Journal of the Society of Toxicology. 120: S130-45. PMID 21163908 DOI: 10.1093/Toxsci/Kfq371  0.358
2011 Swenberg JA, Bordeerat NK, Boysen G, Carro S, Georgieva NI, Nakamura J, Troutman JM, Upton PB, Albertini RJ, Vacek PM, Walker VE, Sram RJ, Goggin M, Tretyakova N. 1,3-Butadiene: Biomarkers and application to risk assessment. Chemico-Biological Interactions. 192: 150-4. PMID 20974116 DOI: 10.1016/J.Cbi.2010.10.010  0.367
2011 Ridpath JR, Takeda S, Swenberg JA, Nakamura J. Convenient, multi-well plate-based DNA damage response analysis using DT40 mutants is applicable to a high-throughput genotoxicity assay with characterization of modes of action. Environmental and Molecular Mutagenesis. 52: 153-60. PMID 20839229 DOI: 10.1002/Em.20595  0.765
2010 Masunaga SI, Tano K, Nakamura J, Watanabe M, Kashino G, Suzuki M, Kinashi Y, Ono K. Adverse effect of mild temperature hyperthermia combined with hexamethylenetetramine compared to its effect combined with tirapazamine in the treatment of solid tumors. Experimental and Therapeutic Medicine. 1: 169-174. PMID 23136610 DOI: 10.3892/Etm_00000027  0.323
2010 Luke AM, Chastain PD, Pachkowski BF, Afonin V, Takeda S, Kaufman DG, Swenberg JA, Nakamura J. Accumulation of true single strand breaks and AP sites in base excision repair deficient cells. Mutation Research. 694: 65-71. PMID 20851134 DOI: 10.1016/J.Mrfmmm.2010.08.008  0.432
2010 Inoue E, Tano K, Yoshii H, Nakamura J, Tada S, Watanabe M, Seki M, Enomoto T. SOD1 Is Essential for the Viability of DT40 Cells and Nuclear SOD1 Functions as a Guardian of Genomic DNA. Journal of Nucleic Acids. 2010. PMID 20811569 DOI: 10.4061/2010/795946  0.403
2010 Chastain PD, Nakamura J, Rao S, Chu H, Ibrahim JG, Swenberg JA, Kaufman DG. Abasic sites preferentially form at regions undergoing DNA replication. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 3674-80. PMID 20511393 DOI: 10.1096/Fj.09-145276  0.392
2010 Asagoshi K, Tano K, Chastain PD, Adachi N, Sonoda E, Kikuchi K, Koyama H, Nagata K, Kaufman DG, Takeda S, Wilson SH, Watanabe M, Swenberg JA, Nakamura J. FEN1 functions in long patch base excision repair under conditions of oxidative stress in vertebrate cells. Molecular Cancer Research : McR. 8: 204-15. PMID 20145043 DOI: 10.1158/1541-7786.Mcr-09-0253  0.369
2010 Masunaga S, Tano K, Nakamura J, Watanabe M, Kashino G, Takahashi A, Tanaka H, Suzuki M, Ohnishi K, Kinashi Y, Liu Y, Ohnishi T, Ono K. Usefulness of hexamethylenetetramine as an adjuvant to radiation and cisplatin in the treatment of solid tumors: its independency of p53 status. Journal of Radiation Research. 51: 27-35. PMID 19801892 DOI: 10.1269/Jrr.09072  0.322
2010 Zhang L, Freeman LE, Nakamura J, Hecht SS, Vandenberg JJ, Smith MT, Sonawane BR. Formaldehyde and leukemia: epidemiology, potential mechanisms, and implications for risk assessment. Environmental and Molecular Mutagenesis. 51: 181-91. PMID 19790261 DOI: 10.1002/Em.20534  0.352
2009 Pachkowski BF, Tano K, Afonin V, Elder RH, Takeda S, Watanabe M, Swenberg JA, Nakamura J. Cells deficient in PARP-1 show an accelerated accumulation of DNA single strand breaks, but not AP sites, over the PARP-1-proficient cells exposed to MMS. Mutation Research. 671: 93-9. PMID 19778542 DOI: 10.1016/J.Mrfmmm.2009.09.006  0.458
2009 Boysen G, Pachkowski BF, Nakamura J, Swenberg JA. The formation and biological significance of N7-guanine adducts. Mutation Research. 678: 76-94. PMID 19465146 DOI: 10.1016/J.Mrgentox.2009.05.006  0.362
2009 Masunaga S, Kono K, Nakamura J, Tano K, Yoshida H, Watanabe M, Kashino G, Suzuki M, Kinashi Y, Liu Y, Ono K. Usefulness of hexamethylenetetramine in combination with chemotherapy using free and pegylated liposomal doxorubicin in vivo, referring to the effect on quiescent cells. Oncology Reports. 21: 1307-12. PMID 19360308 DOI: 10.3892/Or_00000355  0.313
2009 Masunaga SI, Tano K, Watanabe M, Kashino G, Suzuki M, Kinashi Y, Ono K, Nakamura J. Evaluation of the potential of hexamethylenetetramine, compared with tirapazamine, as a combined agent with γ-irradiation and cisplatin treatment in vivo British Journal of Radiology. 82: 392-400. PMID 19153181 DOI: 10.1259/Bjr/54190057  0.303
2008 Damiani LA, Yingling CM, Leng S, Romo PE, Nakamura J, Belinsky SA. Carcinogen-induced gene promoter hypermethylation is mediated by DNMT1 and causal for transformation of immortalized bronchial epithelial cells. Cancer Research. 68: 9005-14. PMID 18974146 DOI: 10.1158/0008-5472.Can-08-1276  0.358
2008 Oka H, Sakai W, Sonoda E, Nakamura J, Asagoshi K, Wilson SH, Kobayashi M, Yamamoto K, Heierhorst J, Takeda S, Taniguchi Y. DNA damage response protein ASCIZ links base excision repair with immunoglobulin gene conversion. Biochemical and Biophysical Research Communications. 371: 225-9. PMID 18433721 DOI: 10.1016/J.Bbrc.2008.04.052  0.438
2007 Ridpath JR, Nakamura A, Tano K, Luke AM, Sonoda E, Arakawa H, Buerstedde JM, Gillespie DA, Sale JE, Yamazoe M, Bishop DK, Takata M, Takeda S, Watanabe M, Swenberg JA, Nakamura J, et al. Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde. Cancer Research. 67: 11117-22. PMID 18056434 DOI: 10.1158/0008-5472.Can-07-3028  0.78
2007 Suraweera A, Becherel OJ, Chen P, Rundle N, Woods R, Nakamura J, Gatei M, Criscuolo C, Filla A, Chessa L, Fusser M, Epe B, Gueven N, Lavin MF. Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage. The Journal of Cell Biology. 177: 969-79. PMID 17562789 DOI: 10.1083/Jcb.200701042  0.462
2007 Tano K, Nakamura J, Asagoshi K, Arakawa H, Sonoda E, Braithwaite EK, Prasad R, Buerstedde JM, Takeda S, Watanabe M, Wilson SH. Interplay between DNA polymerases beta and lambda in repair of oxidation DNA damage in chicken DT40 cells. Dna Repair. 6: 869-75. PMID 17363341 DOI: 10.1016/J.Dnarep.2007.01.011  0.406
2007 Gueven N, Chen P, Nakamura J, Becherel OJ, Kijas AW, Grattan-Smith P, Lavin MF. A subgroup of spinocerebellar ataxias defective in DNA damage responses. Neuroscience. 145: 1418-25. PMID 17224243 DOI: 10.1016/J.Neuroscience.2006.12.010  0.467
2006 Chastain PD, Nakamura J, Swenberg J, Kaufman D. Nonrandom AP site distribution in highly proliferative cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2612-4. PMID 17068113 DOI: 10.1096/Fj.06-6145Fje  0.347
2006 Yoshimura M, Kohzaki M, Nakamura J, Asagoshi K, Sonoda E, Hou E, Prasad R, Wilson SH, Tano K, Yasui A, Lan L, Seki M, Wood RD, Arakawa H, Buerstedde JM, et al. Vertebrate POLQ and POLbeta cooperate in base excision repair of oxidative DNA damage. Molecular Cell. 24: 115-25. PMID 17018297 DOI: 10.1016/J.Molcel.2006.07.032  0.448
2006 Dantzer F, Amé JC, Schreiber V, Nakamura J, Ménissier-de Murcia J, de Murcia G. Poly(ADP-ribose) polymerase-1 activation during DNA damage and repair. Methods in Enzymology. 409: 493-510. PMID 16793420 DOI: 10.1016/S0076-6879(05)09029-4  0.454
2006 Pachkowski BF, Winkel S, Kubota Y, Swenberg JA, Millikan RC, Nakamura J. XRCC1 genotype and breast cancer: functional studies and epidemiologic data show interactions between XRCC1 codon 280 His and smoking. Cancer Research. 66: 2860-8. PMID 16510609 DOI: 10.1158/0008-5472.Can-05-3388  0.325
2006 Cabelof DC, Nakamura J, Heydari AR. A sensitive biochemical assay for the detection of uracil. Environmental and Molecular Mutagenesis. 47: 31-7. PMID 16106443 DOI: 10.1002/Em.20165  0.418
2005 Jeong YC, Nakamura J, Upton PB, Swenberg JA. Pyrimido[1,2-a]-purin-10(3H)-one, M1G, is less prone to artifact than base oxidation. Nucleic Acids Research. 33: 6426-34. PMID 16282591 DOI: 10.1093/Nar/Gki944  0.394
2005 Lin PH, Pan WC, Kang YW, Chen YL, Lin CH, Lee MC, Chou YH, Nakamura J. Effects of naphthalene quinonoids on the induction of oxidative DNA damage and cytotoxicity in calf thymus DNA and in human cultured cells. Chemical Research in Toxicology. 18: 1262-70. PMID 16097799 DOI: 10.1021/Tx050018T  0.481
2005 Rusyn I, Asakura S, Li Y, Kosyk O, Koc H, Nakamura J, Upton PB, Swenberg JA. Effects of ethylene oxide and ethylene inhalation on DNA adducts, apurinic/apyrimidinic sites and expression of base excision DNA repair genes in rat brain, spleen, and liver. Dna Repair. 4: 1099-110. PMID 16051529 DOI: 10.1016/J.Dnarep.2005.05.009  0.409
2005 Rinne ML, He Y, Pachkowski BF, Nakamura J, Kelley MR. N-methylpurine DNA glycosylase overexpression increases alkylation sensitivity by rapidly removing non-toxic 7-methylguanine adducts. Nucleic Acids Research. 33: 2859-67. PMID 15905475 DOI: 10.1093/Nar/Gki601  0.456
2005 McDorman KS, Pachkowski BF, Nakamura J, Wolf DC, Swenberg JA. Oxidative DNA damage from potassium bromate exposure in Long-Evans rats is not enhanced by a mixture of drinking water disinfection by-products. Chemico-Biological Interactions. 152: 107-17. PMID 15840384 DOI: 10.1016/J.Cbi.2005.02.003  0.412
2005 Takanami T, Nakamura J, Kubota Y, Horiuchi S. The Arg280His polymorphism in X-ray repair cross-complementing gene 1 impairs DNA repair ability. Mutation Research. 582: 135-45. PMID 15781218 DOI: 10.1016/J.Mrgentox.2005.01.007  0.423
2005 Lin CH, Leow HT, Huang SC, Nakamura J, Swenberg JA, Lin PH. Induction of cytotoxicity, aldehydic DNA lesions, and poly(ADP-ribose) polymerase-1 activation by catechol derivatives of pentachlorophenol in calf thymus DNA and in human breast cancer cells. Chemical Research in Toxicology. 18: 257-64. PMID 15720130 DOI: 10.1021/Tx0498511  0.472
2005 Jeong YC, Sangaiah R, Nakamura J, Pachkowski BF, Ranasinghe A, Gold A, Ball LM, Swenberg JA. Analysis of M1G-dR in DNA by aldehyde reactive probe labeling and liquid chromatography tandem mass spectrometry. Chemical Research in Toxicology. 18: 51-60. PMID 15651849 DOI: 10.1021/Tx049853L  0.411
2004 Cabelof DC, Raffoul JJ, Nakamura J, Kapoor D, Abdalla H, Heydari AR. Imbalanced base excision repair in response to folate deficiency is accelerated by polymerase beta haploinsufficiency. The Journal of Biological Chemistry. 279: 36504-13. PMID 15218023 DOI: 10.1074/Jbc.M405185200  0.42
2004 Zielinska-Park J, Nakamura J, Swenberg JA, Aitken MD. Aldehydic DNA lesions in calf thymus DNA and HeLa S3 cells produced by bacterial quinone metabolites of fluoranthene and pyrene. Carcinogenesis. 25: 1727-33. PMID 15117810 DOI: 10.1093/Carcin/Bgh174  0.464
2004 Raffoul JJ, Cabelof DC, Nakamura J, Meira LB, Friedberg EC, Heydari AR. Apurinic/apyrimidinic endonuclease (APE/REF-1) haploinsufficient mice display tissue-specific differences in DNA polymerase beta-dependent base excision repair. The Journal of Biological Chemistry. 279: 18425-33. PMID 14973123 DOI: 10.1074/Jbc.M313983200  0.396
2004 Okada T, Iwamoto A, Mukamoto M, Nakamura J, Kusakabe K, Kiso Y, Morioka H, Morikawa Y. Perinatal development of the rat kidney: apoptosis and epidermal growth factor. Congenital Anomalies. 43: 161-7. PMID 14684965 DOI: 10.1111/J.1741-4520.2003.Tb01039.X  0.339
2003 Nakamura J, Asakura S, Hester SD, de Murcia G, Caldecott KW, Swenberg JA. Quantitation of intracellular NAD(P)H can monitor an imbalance of DNA single strand break repair in base excision repair deficient cells in real time. Nucleic Acids Research. 31: e104. PMID 12930978 DOI: 10.1093/Nar/Gng105  0.431
2003 Lin PH, Nakamura J, Yamaguchi S, Asakura S, Swenberg JA. Aldehydic DNA lesions induced by catechol estrogens in calf thymus DNA. Carcinogenesis. 24: 1133-41. PMID 12807746 DOI: 10.1093/Carcin/Bgg049  0.38
2003 Nakamura J, Purvis ER, Swenberg JA. Micromolar concentrations of hydrogen peroxide induce oxidative DNA lesions more efficiently than millimolar concentrations in mammalian cells. Nucleic Acids Research. 31: 1790-5. PMID 12626721 DOI: 10.1093/Nar/Gkg263  0.456
2002 Swenberg JA, Ham AJ, McDorman KS, Morinello EJ, Nakamura J, Schoonhoven R. Methods for measuring DNA adducts and abasic sites I: isolation, purification, and analysis of DNA adducts in intact DNA. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit3.8. PMID 23045079 DOI: 10.1002/0471140856.Tx0308S12  0.459
2002 Sobol RW, Watson DE, Nakamura J, Yakes FM, Hou E, Horton JK, Ladapo J, Van Houten B, Swenberg JA, Tindall KR, Samson LD, Wilson SH. Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress. Proceedings of the National Academy of Sciences of the United States of America. 99: 6860-5. PMID 11983862 DOI: 10.1073/Pnas.092662499  0.415
2001 Lin PH, Nakamura J, Yamaguchi S, La DK, Upton PB, Swenberg JA. Induction of direct adducts, apurinic/apyrimidinic sites and oxidized bases in nuclear DNA of human HeLa S3 tumor cells by tetrachlorohydroquinone. Carcinogenesis. 22: 635-9. PMID 11285200 DOI: 10.1093/Carcin/22.4.635  0.461
2001 Lin PH, Nakamura J, Yamaguchi S, Upton PB, La DK, Swenberg JA. Oxidative damage and direct adducts in calf thymus DNA induced by the pentachlorophenol metabolites, tetrachlorohydroquinone and tetrachloro-1,4-benzoquinone. Carcinogenesis. 22: 627-34. PMID 11285199 DOI: 10.1093/Carcin/22.4.627  0.395
2000 Ríos-Blanco MN, Faller TH, Nakamura J, Kessler W, Kreuzer PE, Ranasinghe A, Filser JG, Swenberg JA. Quantitation of DNA and hemoglobin adducts and apurinic/apyrimidinic sites in tissues of F344 rats exposed to propylene oxide by inhalation. Carcinogenesis. 21: 2011-8. PMID 11062162 DOI: 10.1093/Carcin/21.11.2011  0.387
2000 Nakamura J, La DK, Swenberg JA. 5'-nicked apurinic/apyrimidinic sites are resistant to beta-elimination by beta-polymerase and are persistent in human cultured cells after oxidative stress. The Journal of Biological Chemistry. 275: 5323-8. PMID 10681505 DOI: 10.1074/Jbc.275.8.5323  0.368
1999 Walker VE, Jones IM, Crippen TL, Meng Q, Walker DM, Bauer MJ, Reilly AA, Tates AD, Nakamura J, Upton PB, Skopek TR. Relationships between exposure, cell loss and proliferation, and manifestation of Hprt mutant T cells following treatment of preweanling, weanling, and adult male mice with N-ethyl-N-nitrosourea Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 431: 371-388. PMID 10636002 DOI: 10.1016/S0027-5107(99)00180-3  0.317
1999 Ham AJ, Ranasinghe A, Morinello EJ, Nakamura J, Upton PB, Johnson F, Swenberg JA. Immunoaffinity/gas chromatography/high-resolution mass spectrometry method for the detection of N(2),3-ethenoguanine. Chemical Research in Toxicology. 12: 1240-6. PMID 10604874 DOI: 10.1021/Tx990150R  0.4
1994 Dragan YP, Hully JR, Nakamura J, Mass MJ, Swenberg JA, Pitot HC. Biochemical events during initiation of rat hepatocarcinogenesis. Carcinogenesis. 15: 1451-8. PMID 8033324 DOI: 10.1093/Carcin/15.7.1451  0.327
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