Emmanuel S. Tzanakakis - Publications

Affiliations: 
Chemical and Biological Engineering State University of New York, Buffalo, Buffalo, NY, United States 
Area:
Chemical Engineering, Biomedical Engineering

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ashok P, Tzanakakis ES. Proteomic Analysis of Exosomes during Cardiogenic Differentiation of Human Pluripotent Stem Cells. Cells. 10. PMID 34685602 DOI: 10.3390/cells10102622  0.487
2020 Jacobson EF, Chen Z, Stoukides DM, Nair GG, Hebrok M, Tzanakakis ES. Non-xenogeneic Expansion and Definitive Endoderm Differentiation of Human Pluripotent Stem Cells in an Automated Bioreactor. Biotechnology and Bioengineering. PMID 33205831 DOI: 10.1002/bit.27629  0.561
2020 Ashok P, Parikh A, Du C, Tzanakakis ES. Xenogeneic-Free System for Biomanufacturing of Cardiomyocyte Progeny From Human Pluripotent Stem Cells. Frontiers in Bioengineering and Biotechnology. 8: 571425. PMID 33195131 DOI: 10.3389/fbioe.2020.571425  0.599
2020 Nair GG, Tzanakakis ES, Hebrok M. Emerging routes to the generation of functional β-cells for diabetes mellitus cell therapy. Nature Reviews. Endocrinology. PMID 32587391 DOI: 10.1038/S41574-020-0375-3  0.468
2019 Chen Z, Downing S, Tzanakakis ES. Four Decades After the Discovery of Regenerating Islet-Derived (Reg) Proteins: Current Understanding and Challenges. Frontiers in Cell and Developmental Biology. 7: 235. PMID 31696115 DOI: 10.3389/Fcell.2019.00235  0.33
2019 Zhang F, Tzanakakis ES. Amelioration of diabetes in a murine model upon transplantation of pancreatic β-cells with optogenetic control of cyclic AMP. Acs Synthetic Biology. PMID 31518106 DOI: 10.1021/Acssynbio.9B00262  0.342
2018 Jacobson EF, Tzanakakis ES. Who Will Win: Induced Pluripotent Stem Cells Versus Embryonic Stem Cells for β Cell Replacement and Diabetes Disease Modeling? Current Diabetes Reports. 18: 133. PMID 30343423 DOI: 10.1007/S11892-018-1109-Y  0.642
2017 Zhang F, Tzanakakis ES. Optogenetic regulation of insulin secretion in pancreatic β-cells. Scientific Reports. 7: 9357. PMID 28839233 DOI: 10.1038/S41598-017-09937-0  0.316
2017 Jacobson EF, Tzanakakis ES. Human pluripotent stem cell differentiation to functional pancreatic cells for diabetes therapies: Innovations, challenges and future directions. Journal of Biological Engineering. 11: 21. PMID 28680477 DOI: 10.1186/S13036-017-0066-3  0.584
2016 Fan Y, Zhang F, Tzanakakis ES. Engineering Xeno-Free Microcarriers with Recombinant Vitronectin, Albumin and UV Irradiation for Human Pluripotent Stem Cell Bioprocessing. Acs Biomaterials Science & Engineering. 3: 1510-1518. PMID 28989958 DOI: 10.1021/Acsbiomaterials.6B00253  0.65
2015 Ashok P, Fan Y, Rostami MR, Tzanakakis ES. Aggregate and Microcarrier Cultures of Human Pluripotent Stem Cells in Stirred-Suspension Systems. Methods in Molecular Biology (Clifton, N.J.). PMID 26659793 DOI: 10.1007/7651_2015_312  0.67
2015 Rostami MR, Wu J, Tzanakakis ES. Inverse problem analysis of pluripotent stem cell aggregation dynamics in stirred-suspension cultures. Journal of Biotechnology. 208: 70-9. PMID 26036699 DOI: 10.1016/J.Jbiotec.2015.05.018  0.72
2015 Terranova C, Narla ST, Lee YW, Bard J, Parikh A, Stachowiak EK, Tzanakakis ES, Buck MJ, Birkaya B, Stachowiak MK. Global Developmental Gene Programing Involves a Nuclear Form of Fibroblast Growth Factor Receptor-1 (FGFR1). Plos One. 10: e0123380. PMID 25923916 DOI: 10.1371/Journal.Pone.0123380  0.412
2015 Parikh A, Wu J, Blanton RM, Tzanakakis ES. Signaling Pathways and Gene Regulatory Networks in Cardiomyocyte Differentiation. Tissue Engineering. Part B, Reviews. 21: 377-392. PMID 25813860 DOI: 10.1089/Ten.Teb.2014.0662  0.67
2015 Wu J, Fan Y, Tzanakakis ES. Increased culture density is linked to decelerated proliferation, prolonged G1 phase, and enhanced propensity for differentiation of self-renewing human pluripotent stem cells. Stem Cells and Development. 24: 892-903. PMID 25405279 DOI: 10.1089/Scd.2014.0384  0.706
2015 Fan Y, Wu J, Ashok P, Hsiung M, Tzanakakis ES. Production of human pluripotent stem cell therapeutics under defined xeno-free conditions: progress and challenges. Stem Cell Reviews. 11: 96-109. PMID 25077810 DOI: 10.1007/S12015-014-9544-X  0.719
2014 Wu J, Rostami MR, Cadavid Olaya DP, Tzanakakis ES. Oxygen transport and stem cell aggregation in stirred-suspension bioreactor cultures. Plos One. 9: e102486. PMID 25032842 DOI: 10.1371/Journal.Pone.0102486  0.692
2014 Chen CK, Law WC, Aalinkeel R, Yu Y, Nair B, Wu J, Mahajan S, Reynolds JL, Li Y, Lai CK, Tzanakakis ES, Schwartz SA, Prasad PN, Cheng C. Biodegradable cationic polymeric nanocapsules for overcoming multidrug resistance and enabling drug-gene co-delivery to cancer cells. Nanoscale. 6: 1567-72. PMID 24326457 DOI: 10.1039/C3Nr04804G  0.557
2014 Fan Y, Hsiung M, Cheng C, Tzanakakis ES. Facile engineering of xeno-free microcarriers for the scalable cultivation of human pluripotent stem cells in stirred suspension. Tissue Engineering. Part A. 20: 588-99. PMID 24098972 DOI: 10.1089/Ten.Tea.2013.0219  0.616
2014 Kaplan AD, Lis A, Cimato TR, Tzanakakis ES, Zhou Q, Morales MJ, Rasmusson RL, Bett GC. Enhanced Differentiation of Stem Cell Derived Cardiac Myocytes by Electronic Expression of IK1 Reveals an Atrial-Specific Kv1.5-Like Current Biophysical Journal. 106: 631a. DOI: 10.1016/J.Bpj.2013.11.3490  0.474
2013 Tzanakakis ES, Hu WS. Stem cell science has made major strides in the last few years. Introduction. Biotechnology Advances. 31: 993. PMID 24176141 DOI: 10.1016/J.Biotechadv.2013.10.004  0.563
2013 Bett GC, Kaplan AD, Lis A, Cimato TR, Tzanakakis ES, Zhou Q, Morales MJ, Rasmusson RL. Electronic "expression" of the inward rectifier in cardiocytes derived from human-induced pluripotent stem cells. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 10: 1903-10. PMID 24055949 DOI: 10.1016/j.hrthm.2013.09.061  0.451
2013 Wu J, Tzanakakis ES. Deconstructing stem cell population heterogeneity: single-cell analysis and modeling approaches. Biotechnology Advances. 31: 1047-62. PMID 24035899 DOI: 10.1016/J.Biotechadv.2013.09.001  0.754
2013 Wu J, Rostami MR, Tzanakakis ES. Stem cell modeling: From gene networks to cell populations. Current Opinion in Chemical Engineering. 2: 17-25. PMID 23914346 DOI: 10.1016/J.Coche.2013.01.001  0.745
2013 Wu J, Tzanakakis ES. Distinct allelic patterns of nanog expression impart embryonic stem cell population heterogeneity. Plos Computational Biology. 9: e1003140. PMID 23874182 DOI: 10.1371/Journal.Pcbi.1003140  0.728
2012 Wu J, Tzanakakis ES. Contribution of stochastic partitioning at human embryonic stem cell division to NANOG heterogeneity. Plos One. 7: e50715. PMID 23226362 DOI: 10.1371/Journal.Pone.0050715  0.727
2012 Parikh A, Stephan AF, Tzanakakis ES. Regenerating proteins and their expression, regulation and signaling. Biomolecular Concepts. 3: 57-70. PMID 22582090 DOI: 10.1515/Bmc.2011.055  0.362
2012 Lee YW, Terranova C, Birkaya B, Narla S, Kehoe D, Parikh A, Dong S, Ratzka A, Brinkmann H, Aletta JM, Tzanakakis ES, Stachowiak EK, Claus P, Stachowiak MK. A novel nuclear FGF Receptor-1 partnership with retinoid and Nur receptors during developmental gene programming of embryonic stem cells. Journal of Cellular Biochemistry. 113: 2920-36. PMID 22539306 DOI: 10.1002/Jcb.24170  0.381
2012 Patil SA, Chandrasekaran EV, Matta KL, Parikh A, Tzanakakis ES, Neelamegham S. Scaling down the size and increasing the throughput of glycosyltransferase assays: activity changes on stem cell differentiation. Analytical Biochemistry. 425: 135-44. PMID 22449497 DOI: 10.1016/J.Ab.2012.03.009  0.458
2011 Lock LT, Laychock SG, Tzanakakis ES. Pseudoislets in stirred-suspension culture exhibit enhanced cell survival, propagation and insulin secretion. Journal of Biotechnology. 151: 278-86. PMID 21185337 DOI: 10.1016/J.Jbiotec.2010.12.015  0.435
2011 Jing D, Parikh A, Tzanakakis ES. Stem cell bioprocessing for regenerative medicine Stem Cells: From Mechanisms to Technologies. 197-229. DOI: 10.1142/9789814317931_0007  0.702
2011 Stachowiak MK, Stachowiak EK, Aletta JM, Tzanakakis ES. A common integrative nuclear signaling module for stem cell development Stem Cells: From Mechanisms to Technologies. 87-132. DOI: 10.1142/9789814317931_0004  0.543
2011 Stachowiak MK, Tzanakakis ES. Stem cells: From mechanisms to technologies Stem Cells: From Mechanisms to Technologies. 1-377. DOI: 10.1142/7849  0.574
2010 Jing D, Parikh A, Tzanakakis ES. Cardiac cell generation from encapsulated embryonic stem cells in static and scalable culture systems. Cell Transplantation. 19: 1397-412. PMID 20587137 DOI: 10.3727/096368910X513955  0.715
2010 Jing D, Kehoe DE, Tzanakakis ES. Expression of Reg family proteins in embryonic stem cells and its modulation by Wnt/beta-catenin signaling. Stem Cells and Development. 19: 1307-19. PMID 20050810 DOI: 10.1089/Scd.2009.0398  0.669
2010 Kehoe DE, Jing D, Lock LT, Tzanakakis ES. Scalable stirred-suspension bioreactor culture of human pluripotent stem cells. Tissue Engineering. Part A. 16: 405-21. PMID 19739936 DOI: 10.1089/Ten.Tea.2009.0454  0.748
2009 Lock LT, Tzanakakis ES. Expansion and differentiation of human embryonic stem cells to endoderm progeny in a microcarrier stirred-suspension culture. Tissue Engineering. Part A. 15: 2051-63. PMID 19196140 DOI: 10.1089/Ten.Tea.2008.0455  0.571
2008 Kehoe DE, Lock LT, Parikh A, Tzanakakis ES. Propagation of embryonic stem cells in stirred suspension without serum. Biotechnology Progress. 24: 1342-52. PMID 19194949 DOI: 10.1002/Btpr.57  0.619
2008 Jing D, Parikh A, Canty JM, Tzanakakis ES. Stem cells for heart cell therapies. Tissue Engineering. Part B, Reviews. 14: 393-406. PMID 18821841 DOI: 10.1089/Ten.Teb.2008.0262  0.674
2007 Chemler JA, Lock LT, Koffas MA, Tzanakakis ES. Standardized biosynthesis of flavan-3-ols with effects on pancreatic beta-cell insulin secretion. Applied Microbiology and Biotechnology. 77: 797-807. PMID 17938905 DOI: 10.1007/S00253-007-1227-Y  0.34
2007 Lock LT, Tzanakakis ES. Stem/Progenitor cell sources of insulin-producing cells for the treatment of diabetes. Tissue Engineering. 13: 1399-412. PMID 17550339 DOI: 10.1089/Ten.2007.0047  0.572
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