Xiaodong Cheng - Publications

Emory University, Atlanta, GA 

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Woodcock CB, Yu D, Zhang X, Cheng X. Human HemK2/KMT9/N6AMT1 is an active protein methyltransferase, but does not act on DNA in vitro, in the presence of Trm112. Cell Discovery. 5: 50. PMID 31632689 DOI: 10.1038/s41421-019-0119-5  0.48
2019 Yang J, Zhang X, Blumenthal RM, Cheng X. JMB Special Issue on "Reading DNA and RNA methylation" Detection of DNA modifications by sequence-specific transcription factors. Journal of Molecular Biology. PMID 31626807 DOI: 10.1016/j.jmb.2019.09.013  0.48
2019 Horton JR, Woodcock CB, Opot SB, Reich NO, Zhang X, Cheng X. The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site. Nature Communications. 10: 4600. PMID 31601797 DOI: 10.1038/s41467-019-12498-7  0.48
2019 Zhang X, Cheng X, Yin B, Wang J, Li S, Liu G, Hu Z, Wu W, Zhang Y. Finite element analysis of spiral plate and Herbert screw fixation for treatment of midshaft clavicle fractures. Medicine. 98: e16898. PMID 31441868 DOI: 10.1097/MD.0000000000016898  0.48
2019 Dai S, Horton JR, Woodcock CB, Wilkinson AW, Zhang X, Gozani O, Cheng X. Structural basis for the target specificity of actin histidine methyltransferase SETD3. Nature Communications. 10: 3541. PMID 31388018 DOI: 10.1038/s41467-019-11554-6  0.48
2019 Li W, Meng Y, Wang Y, Cheng X, Wang C, Xiao S, Zhang X, Deng Z, Hu M, Shen P, Xu S, Fu C, Jiang W, Wu B, Li K, et al. Association of age and viral factors with high-risk HPV persistence: A retrospective follow-up study. Gynecologic Oncology. PMID 31242966 DOI: 10.1016/j.ygyno.2019.05.026  0.48
2019 Ren R, Hardikar S, Horton JR, Lu Y, Zeng Y, Singh AK, Lin K, Coletta LD, Shen J, Lin Kong CS, Hashimoto H, Zhang X, Chen T, Cheng X. Structural basis of specific DNA binding by the transcription factor ZBTB24. Nucleic Acids Research. PMID 31226215 DOI: 10.1093/nar/gkz557  0.48
2019 Wang Y, Meng Y, Li W, Zhang X, Deng Z, Hu M, Shen P, Xu S, Fu C, Jiang W, Wu B, Li K, Chen G, Wei J, Xi L, ... ... Cheng X, et al. Prevalence and Characteristics of hrHPV Infection among 414,540 Women: A Multicenter Study in Central and Eastern China. Journal of Cancer. 10: 1902-1908. PMID 31205548 DOI: 10.7150/jca.30157  0.48
2019 Yang J, Horton JR, Li J, Huang Y, Zhang X, Blumenthal RM, Cheng X. Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine. Nucleic Acids Research. PMID 31081034 DOI: 10.1093/nar/gkz381  0.48
2019 Wang J, Zhang X, Li S, Yin B, Liu G, Cheng X, Zhang Y. Plating System Design Determines Mechanical Environment in Long Bone Mid-shaft Fractures: A Finite Element Analysis. Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research. 1-10. PMID 30885085 DOI: 10.1080/08941939.2019.1567875  0.48
2018 Wilkinson AW, Diep J, Dai S, Liu S, Ooi YS, Song D, Li TM, Horton JR, Zhang X, Liu C, Trivedi DV, Ruppel KM, Vilches-Moure JG, Casey KM, Mak J, ... ... Cheng X, et al. SETD3 is an actin histidine methyltransferase that prevents primary dystocia. Nature. PMID 30626964 DOI: 10.1038/s41586-018-0821-8  0.48
2018 Yang J, Horton JR, Wang D, Ren R, Li J, Sun D, Huang Y, Zhang X, Blumenthal RM, Cheng X. Structural basis for effects of CpA modifications on C/EBPβ binding of DNA. Nucleic Acids Research. PMID 30566668 DOI: 10.1093/nar/gky1264  0.48
2018 Horton JR, Woodcock CB, Chen Q, Liu X, Zhang X, Shanks J, Rai G, Mott BT, Jansen DJ, Kales SC, Henderson MJ, Cyr M, Pohida K, Hu X, Shah P, ... ... Cheng X, et al. Structure-based engineering of irreversible inhibitors against histone lysine demethylase KDM5A. Journal of Medicinal Chemistry. PMID 30392349 DOI: 10.1021/acs.jmedchem.8b01219  0.48
2018 Ren R, Horton JR, Zhang X, Blumenthal RM, Cheng X. Detecting and interpreting DNA methylation marks. Current Opinion in Structural Biology. 53: 88-99. PMID 30031306 DOI: 10.1016/j.sbi.2018.06.004  0.48
2018 Patel A, Yang P, Tinkham M, Pradhan M, Sun MA, Wang Y, Hoang D, Wolf G, Horton JR, Zhang X, Macfarlan T, Cheng X. DNA Conformation Induces Adaptable Binding by Tandem Zinc Finger Proteins. Cell. PMID 29551271 DOI: 10.1016/j.cell.2018.02.058  0.48
2018 Horton JR, Liu X, Wu L, Zhang K, Shanks J, Zhang X, Rai G, Mott BT, Jansen DJ, Kales SC, Henderson MJ, Pohida K, Fang Y, Hu X, Jadhav A, ... ... Cheng X, et al. Insights into the action of inhibitor enantiomers against histone lysine demethylase 5A. Journal of Medicinal Chemistry. PMID 29537847 DOI: 10.1021/acs.jmedchem.8b00261  0.48
2018 Zhao X, Wu Q, Wang X, Fu Y, Zhang X, Tian X, Cheng B, Lu B, Yu X, Lan S, Lu W, Ma D, Cheng X, Xie X. The performance of human papillomavirus DNA detection with type 16/18 genotyping by hybrid capture in primary test of cervical cancer screening: A cross-sectional study in 10,669 Chinese women. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. PMID 29518562 DOI: 10.1016/j.cmi.2018.02.027  0.48
2017 Wang D, Horton JR, Zheng Y, Blumenthal RM, Zhang X, Cheng X. Role for first zinc finger of WT1 in DNA sequence specificity: Denys-Drash syndrome-associated WT1 mutant in ZF1 enhances affinity for a subset of WT1 binding sites. Nucleic Acids Research. PMID 29294058 DOI: 10.1093/nar/gkx1274  0.48
2017 Murray IA, Morgan RD, Luyten Y, Fomenkov A, Corrêa IR, Dai N, Allaw MB, Zhang X, Cheng X, Roberts RJ. The non-specific adenine DNA methyltransferase M.EcoGII. Nucleic Acids Research. PMID 29228259 DOI: 10.1093/nar/gkx1191  0.48
2017 Patel A, Zhang X, Blumenthal RM, Cheng X. Structural basis of human PRDM9 allele C specific recognition of its cognate DNA sequence. The Journal of Biological Chemistry. PMID 28801461 DOI: 10.1074/jbc.M117.805754  0.48
2017 Hashimoto H, Wang D, Horton JR, Zhang X, Corces VG, Cheng X. Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. Molecular Cell. PMID 28529057 DOI: 10.1016/j.molcel.2017.05.004  0.48
2017 Wu Q, Zhao X, Fu Y, Wang X, Zhang X, Tian X, Cheng B, Lu B, Yu X, Lan S, Lu W, Ma D, Cheng X, Xie X. A cross-sectional study on HPV testing with type 16/18 genotyping for cervical cancer screening in 11,064 Chinese women. Cancer Medicine. PMID 28378404 DOI: 10.1002/cam4.1060  0.48
2017 Hong S, Wang D, Horton JR, Zhang X, Speck SH, Blumenthal RM, Cheng X. Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta. Nucleic Acids Research. PMID 28158710 DOI: 10.1093/nar/gkx057  0.48
2016 Wang D, Hashimoto H, Zhang X, Barwick BG, Lonial S, Boise LH, Vertino PM, Cheng X. MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma. Nucleic Acids Research. PMID 27903915 DOI: 10.1093/nar/gkw1184  0.48
2016 Hashimoto H, Zhang X, Zheng Y, Wilson GG, Cheng X. Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications. Nucleic Acids Research. PMID 27596598 DOI: 10.1093/nar/gkw766  0.48
2016 Hashimoto H, Wang D, Steves AN, Jin P, Blumenthal RM, Zhang X, Cheng X. Distinctive Klf4 mutants determine preference for DNA methylation status. Nucleic Acids Research. PMID 27596594 DOI: 10.1093/nar/gkw774  0.48
2016 Horton JR, Liu X, Gale M, Wu L, Shanks JR, Zhang X, Webber PJ, Bell JS, Kales SC, Mott BT, Rai G, Jansen DJ, Henderson MJ, Urban DJ, Hall MD, ... ... Cheng X, et al. Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds. Cell Chemical Biology. PMID 27427228 DOI: 10.1016/j.chembiol.2016.06.006  0.48
2016 Patel A, Horton JR, Wilson GG, Zhang X, Cheng X. Structural basis for human PRDM9 action at recombination hot spots. Genes & Development. 30: 257-65. PMID 26833727 DOI: 10.1101/gad.274928.115  0.48
2015 Horton JR, Engstrom A, Zoeller EL, Liu X, Shanks JR, Zhang X, Johns MA, Vertino PM, Fu H, Cheng X. Characterization of a linked Jumonji domain of the KDM5/JARID1 family of histone H3 lysine 4 demethylases. The Journal of Biological Chemistry. PMID 26645689 DOI: 10.1074/jbc.M115.698449  0.48
2015 Hashimoto H, Pais JE, Dai N, Corrêa IR, Zhang X, Zheng Y, Cheng X. Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA. Nucleic Acids Research. PMID 26323320 DOI: 10.1093/nar/gkv870  0.48
2015 Hashimoto H, Zhang X, Vertino PM, Cheng X. The Mechanisms of Generation, Recognition, and Erasure of DNA 5-Methylcytosine and Thymine Oxidations. The Journal of Biological Chemistry. 290: 20723-33. PMID 26152719 DOI: 10.1074/jbc.R115.656884  0.48
2015 Horton JR, Zhang X, Blumenthal RM, Cheng X. Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression. Nucleic Acids Research. 43: 4296-308. PMID 25845600 DOI: 10.1093/nar/gkv251  0.48
2014 Horton JR, Wang H, Mabuchi MY, Zhang X, Roberts RJ, Zheng Y, Wilson GG, Cheng X. Modification-dependent restriction endonuclease, MspJI, flips 5-methylcytosine out of the DNA helix. Nucleic Acids Research. 42: 12092-101. PMID 25262349 DOI: 10.1093/nar/gku871  0.48
2014 Hashimoto H, Olanrewaju YO, Zheng Y, Wilson GG, Zhang X, Cheng X. Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence. Genes & Development. 28: 2304-13. PMID 25258363 DOI: 10.1101/gad.250746.114  0.48
2014 Hong S, Hashimoto H, Kow YW, Zhang X, Cheng X. The carboxy-terminal domain of ROS1 is essential for 5-methylcytosine DNA glycosylase activity. Journal of Molecular Biology. 426: 3703-12. PMID 25240767 DOI: 10.1016/j.jmb.2014.09.010  0.48
2014 Kao TH, Liao HF, Wolf D, Tai KY, Chuang CY, Lee HS, Kuo HC, Hata K, Zhang X, Cheng X, Goff SP, Ooi SK, Bestor TH, Lin SP. Ectopic DNMT3L triggers assembly of a repressive complex for retroviral silencing in somatic cells. Journal of Virology. 88: 10680-95. PMID 24991018 DOI: 10.1128/JVI.01176-14  0.48
2014 Horton JR, Borgaro JG, Griggs RM, Quimby A, Guan S, Zhang X, Wilson GG, Zheng Y, Zhu Z, Cheng X. Structure of 5-hydroxymethylcytosine-specific restriction enzyme, AbaSI, in complex with DNA. Nucleic Acids Research. 42: 7947-59. PMID 24895434 DOI: 10.1093/nar/gku497  0.48
2014 Horton JR, Nugent RL, Li A, Mabuchi MY, Fomenkov A, Cohen-Karni D, Griggs RM, Zhang X, Wilson GG, Zheng Y, Xu SY, Cheng X. Structure and mutagenesis of the DNA modification-dependent restriction endonuclease AspBHI. Scientific Reports. 4: 4246. PMID 24604015 DOI: 10.1038/srep04246  0.48
2014 Liu Y, Olanrewaju YO, Zheng Y, Hashimoto H, Blumenthal RM, Zhang X, Cheng X. Structural basis for Klf4 recognition of methylated DNA. Nucleic Acids Research. 42: 4859-67. PMID 24520114 DOI: 10.1093/nar/gku134  0.48
2014 Hashimoto H, Pais JE, Zhang X, Saleh L, Fu ZQ, Dai N, Corrêa IR, Zheng Y, Cheng X. Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA. Nature. 506: 391-5. PMID 24390346 DOI: 10.1038/nature12905  0.48
2014 Valente S, Liu Y, Schnekenburger M, Zwergel C, Cosconati S, Gros C, Tardugno M, Labella D, Florean C, Minden S, Hashimoto H, Chang Y, Zhang X, Kirsch G, Novellino E, ... ... Cheng X, et al. Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells. Journal of Medicinal Chemistry. 57: 701-13. PMID 24387159 DOI: 10.1021/jm4012627  0.48
2013 Liu Y, Olanrewaju YO, Zhang X, Cheng X. DNA recognition of 5-carboxylcytosine by a Zfp57 mutant at an atomic resolution of 0.97 Å. Biochemistry. 52: 9310-7. PMID 24236546 DOI: 10.1021/bi401360n  0.48
2013 Hashimoto H, Zhang X, Cheng X. Activity and crystal structure of human thymine DNA glycosylase mutant N140A with 5-carboxylcytosine DNA at low pH. Dna Repair. 12: 535-40. PMID 23680598 DOI: 10.1016/j.dnarep.2013.04.003  0.48
2013 Liu Y, Zhang X, Blumenthal RM, Cheng X. A common mode of recognition for methylated CpG. Trends in Biochemical Sciences. 38: 177-83. PMID 23352388 DOI: 10.1016/j.tibs.2012.12.005  0.48
2013 Hashimoto H, Zhang X, Cheng X. Selective excision of 5-carboxylcytosine by a thymine DNA glycosylase mutant. Journal of Molecular Biology. 425: 971-6. PMID 23337108 DOI: 10.1016/j.jmb.2013.01.013  0.48
2012 Liu Y, Toh H, Sasaki H, Zhang X, Cheng X. An atomic model of Zfp57 recognition of CpG methylation within a specific DNA sequence. Genes & Development. 26: 2374-9. PMID 23059534 DOI: 10.1101/gad.202200.112  0.48
2012 Hashimoto H, Hong S, Bhagwat AS, Zhang X, Cheng X. Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylation. Nucleic Acids Research. 40: 10203-14. PMID 22962365 DOI: 10.1093/nar/gks845  0.48
2012 Horton JR, Mabuchi MY, Cohen-Karni D, Zhang X, Griggs RM, Samaranayake M, Roberts RJ, Zheng Y, Cheng X. Structure and cleavage activity of the tetrameric MspJI DNA modification-dependent restriction endonuclease. Nucleic Acids Research. 40: 9763-73. PMID 22848107 DOI: 10.1093/nar/gks719  0.48
2012 Hashimoto H, Zhang X, Cheng X. Excision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: structural basis and implications for active DNA demethylation. Nucleic Acids Research. 40: 8276-84. PMID 22740654 DOI: 10.1093/nar/gks628  0.48
2012 Hashimoto H, Liu Y, Upadhyay AK, Chang Y, Howerton SB, Vertino PM, Zhang X, Cheng X. Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation. Nucleic Acids Research. 40: 4841-9. PMID 22362737 DOI: 10.1093/nar/gks155  0.48
2008 Jurkowska RZ, Anspach N, Urbanke C, Jia D, Reinhardt R, Nellen W, Cheng X, Jeltsch A. Formation of nucleoprotein filaments by mammalian DNA methyltransferase Dnmt3a in complex with regulator Dnmt3L. Nucleic Acids Research. 36: 6656-63. PMID 18945701 DOI: 10.1093/nar/gkn747  0.48
2008 Subramanian K, Jia D, Kapoor-Vazirani P, Powell DR, Collins RE, Sharma D, Peng J, Cheng X, Vertino PM. Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase. Molecular Cell. 30: 336-47. PMID 18471979 DOI: 10.1016/j.molcel.2008.03.022  0.48
2008 Dhayalan A, Jurkowski TP, Laser H, Reinhardt R, Jia D, Cheng X, Jeltsch A. Mapping of protein-protein interaction sites by the 'absence of interference' approach. Journal of Molecular Biology. 376: 1091-9. PMID 18191145 DOI: 10.1016/j.jmb.2007.12.032  0.48
2007 Jia D, Jurkowska RZ, Zhang X, Jeltsch A, Cheng X. Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation. Nature. 449: 248-51. PMID 17713477 DOI: 10.1038/nature06146  0.48
2007 Ooi SK, Qiu C, Bernstein E, Li K, Jia D, Yang Z, Erdjument-Bromage H, Tempst P, Lin SP, Allis CD, Cheng X, Bestor TH. DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature. 448: 714-7. PMID 17687327 DOI: 10.1038/nature05987  0.48
2005 Collins RE, Tachibana M, Tamaru H, Smith KM, Jia D, Zhang X, Selker EU, Shinkai Y, Cheng X. In vitro and in vivo analyses of a Phe/Tyr switch controlling product specificity of histone lysine methyltransferases. The Journal of Biological Chemistry. 280: 5563-70. PMID 15590646 DOI: 10.1074/jbc.M410483200  0.48
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