Xiaodong Cheng - Publications

Emory University, Atlanta, GA 

59/210 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Dai S, Horton JR, Wilkinson AW, Gozani O, Zhang X, Cheng X. An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation. The Journal of Biological Chemistry. PMID 31911441 DOI: 10.1074/jbc.RA119.012319  0.48
2019 Woodcock CB, Yu D, Hajian T, Li J, Huang Y, Dai N, Corrêa IR, Wu T, Vedadi M, Zhang X, Cheng X. Human MettL3-MettL14 complex is a sequence-specific DNA adenine methyltransferase active on single-strand and unpaired DNA in vitro. Cell Discovery. 5: 63. PMID 31885874 DOI: 10.1038/s41421-019-0136-4  0.48
2019 Horton JR, Yang J, Zhang X, Petronzio T, Fomenkov A, Wilson GG, Roberts RJ, Cheng X. Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 Å. Nucleic Acids Research. PMID 31879785 DOI: 10.1093/nar/gkz1195  0.48
2019 Woodcock CB, Yu D, Zhang X, Cheng X. Human HemK2/KMT9/N6AMT1 is an active protein methyltransferase, but does not act on DNA in vitro, in the presence of Trm112. Cell Discovery. 5: 50. PMID 31632689 DOI: 10.1038/s41421-019-0119-5  0.48
2019 Yang J, Zhang X, Blumenthal RM, Cheng X. JMB Special Issue on "Reading DNA and RNA methylation" Detection of DNA modifications by sequence-specific transcription factors. Journal of Molecular Biology. PMID 31626807 DOI: 10.1016/j.jmb.2019.09.013  0.48
2019 Horton JR, Woodcock CB, Opot SB, Reich NO, Zhang X, Cheng X. The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site. Nature Communications. 10: 4600. PMID 31601797 DOI: 10.1038/s41467-019-12498-7  0.48
2019 Zhang X, Cheng X, Yin B, Wang J, Li S, Liu G, Hu Z, Wu W, Zhang Y. Finite element analysis of spiral plate and Herbert screw fixation for treatment of midshaft clavicle fractures. Medicine. 98: e16898. PMID 31441868 DOI: 10.1097/MD.0000000000016898  0.48
2019 Dai S, Horton JR, Woodcock CB, Wilkinson AW, Zhang X, Gozani O, Cheng X. Structural basis for the target specificity of actin histidine methyltransferase SETD3. Nature Communications. 10: 3541. PMID 31388018 DOI: 10.1038/s41467-019-11554-6  0.48
2019 Li W, Meng Y, Wang Y, Cheng X, Wang C, Xiao S, Zhang X, Deng Z, Hu M, Shen P, Xu S, Fu C, Jiang W, Wu B, Li K, et al. Association of age and viral factors with high-risk HPV persistence: A retrospective follow-up study. Gynecologic Oncology. PMID 31242966 DOI: 10.1016/j.ygyno.2019.05.026  0.48
2019 Ren R, Hardikar S, Horton JR, Lu Y, Zeng Y, Singh AK, Lin K, Coletta LD, Shen J, Lin Kong CS, Hashimoto H, Zhang X, Chen T, Cheng X. Structural basis of specific DNA binding by the transcription factor ZBTB24. Nucleic Acids Research. PMID 31226215 DOI: 10.1093/nar/gkz557  0.48
2019 Wang Y, Meng Y, Li W, Zhang X, Deng Z, Hu M, Shen P, Xu S, Fu C, Jiang W, Wu B, Li K, Chen G, Wei J, Xi L, ... ... Cheng X, et al. Prevalence and Characteristics of hrHPV Infection among 414,540 Women: A Multicenter Study in Central and Eastern China. Journal of Cancer. 10: 1902-1908. PMID 31205548 DOI: 10.7150/jca.30157  0.48
2019 Yang J, Horton JR, Li J, Huang Y, Zhang X, Blumenthal RM, Cheng X. Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine. Nucleic Acids Research. PMID 31081034 DOI: 10.1093/nar/gkz381  0.48
2019 Wang J, Zhang X, Li S, Yin B, Liu G, Cheng X, Zhang Y. Plating System Design Determines Mechanical Environment in Long Bone Mid-shaft Fractures: A Finite Element Analysis. Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research. 1-10. PMID 30885085 DOI: 10.1080/08941939.2019.1567875  0.48
2018 Wilkinson AW, Diep J, Dai S, Liu S, Ooi YS, Song D, Li TM, Horton JR, Zhang X, Liu C, Trivedi DV, Ruppel KM, Vilches-Moure JG, Casey KM, Mak J, ... ... Cheng X, et al. SETD3 is an actin histidine methyltransferase that prevents primary dystocia. Nature. PMID 30626964 DOI: 10.1038/s41586-018-0821-8  0.48
2018 Yang J, Horton JR, Wang D, Ren R, Li J, Sun D, Huang Y, Zhang X, Blumenthal RM, Cheng X. Structural basis for effects of CpA modifications on C/EBPβ binding of DNA. Nucleic Acids Research. PMID 30566668 DOI: 10.1093/nar/gky1264  0.48
2018 Horton JR, Woodcock CB, Chen Q, Liu X, Zhang X, Shanks J, Rai G, Mott BT, Jansen DJ, Kales SC, Henderson MJ, Cyr M, Pohida K, Hu X, Shah P, ... ... Cheng X, et al. Structure-based engineering of irreversible inhibitors against histone lysine demethylase KDM5A. Journal of Medicinal Chemistry. PMID 30392349 DOI: 10.1021/acs.jmedchem.8b01219  0.48
2018 Ren R, Horton JR, Zhang X, Blumenthal RM, Cheng X. Detecting and interpreting DNA methylation marks. Current Opinion in Structural Biology. 53: 88-99. PMID 30031306 DOI: 10.1016/j.sbi.2018.06.004  0.48
2018 Patel A, Yang P, Tinkham M, Pradhan M, Sun MA, Wang Y, Hoang D, Wolf G, Horton JR, Zhang X, Macfarlan T, Cheng X. DNA Conformation Induces Adaptable Binding by Tandem Zinc Finger Proteins. Cell. PMID 29551271 DOI: 10.1016/j.cell.2018.02.058  0.48
2018 Horton JR, Liu X, Wu L, Zhang K, Shanks J, Zhang X, Rai G, Mott BT, Jansen DJ, Kales SC, Henderson MJ, Pohida K, Fang Y, Hu X, Jadhav A, ... ... Cheng X, et al. Insights into the action of inhibitor enantiomers against histone lysine demethylase 5A. Journal of Medicinal Chemistry. PMID 29537847 DOI: 10.1021/acs.jmedchem.8b00261  0.48
2018 Zhao X, Wu Q, Wang X, Fu Y, Zhang X, Tian X, Cheng B, Lu B, Yu X, Lan S, Lu W, Ma D, Cheng X, Xie X. The performance of human papillomavirus DNA detection with type 16/18 genotyping by hybrid capture in primary test of cervical cancer screening: A cross-sectional study in 10,669 Chinese women. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. PMID 29518562 DOI: 10.1016/j.cmi.2018.02.027  0.48
2017 Wang D, Horton JR, Zheng Y, Blumenthal RM, Zhang X, Cheng X. Role for first zinc finger of WT1 in DNA sequence specificity: Denys-Drash syndrome-associated WT1 mutant in ZF1 enhances affinity for a subset of WT1 binding sites. Nucleic Acids Research. PMID 29294058 DOI: 10.1093/nar/gkx1274  0.48
2017 Murray IA, Morgan RD, Luyten Y, Fomenkov A, Corrêa IR, Dai N, Allaw MB, Zhang X, Cheng X, Roberts RJ. The non-specific adenine DNA methyltransferase M.EcoGII. Nucleic Acids Research. PMID 29228259 DOI: 10.1093/nar/gkx1191  0.48
2017 Patel A, Zhang X, Blumenthal RM, Cheng X. Structural basis of human PRDM9 allele C specific recognition of its cognate DNA sequence. The Journal of Biological Chemistry. PMID 28801461 DOI: 10.1074/jbc.M117.805754  0.48
2017 Hashimoto H, Wang D, Horton JR, Zhang X, Corces VG, Cheng X. Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. Molecular Cell. PMID 28529057 DOI: 10.1016/j.molcel.2017.05.004  0.48
2017 Wu Q, Zhao X, Fu Y, Wang X, Zhang X, Tian X, Cheng B, Lu B, Yu X, Lan S, Lu W, Ma D, Cheng X, Xie X. A cross-sectional study on HPV testing with type 16/18 genotyping for cervical cancer screening in 11,064 Chinese women. Cancer Medicine. PMID 28378404 DOI: 10.1002/cam4.1060  0.48
2017 Hong S, Wang D, Horton JR, Zhang X, Speck SH, Blumenthal RM, Cheng X. Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta. Nucleic Acids Research. PMID 28158710 DOI: 10.1093/nar/gkx057  0.48
2016 Wang D, Hashimoto H, Zhang X, Barwick BG, Lonial S, Boise LH, Vertino PM, Cheng X. MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma. Nucleic Acids Research. PMID 27903915 DOI: 10.1093/nar/gkw1184  0.48
2016 Hashimoto H, Zhang X, Zheng Y, Wilson GG, Cheng X. Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications. Nucleic Acids Research. PMID 27596598 DOI: 10.1093/nar/gkw766  0.48
2016 Hashimoto H, Wang D, Steves AN, Jin P, Blumenthal RM, Zhang X, Cheng X. Distinctive Klf4 mutants determine preference for DNA methylation status. Nucleic Acids Research. PMID 27596594 DOI: 10.1093/nar/gkw774  0.48
2016 Horton JR, Liu X, Gale M, Wu L, Shanks JR, Zhang X, Webber PJ, Bell JS, Kales SC, Mott BT, Rai G, Jansen DJ, Henderson MJ, Urban DJ, Hall MD, ... ... Cheng X, et al. Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds. Cell Chemical Biology. PMID 27427228 DOI: 10.1016/j.chembiol.2016.06.006  0.48
2016 Patel A, Horton JR, Wilson GG, Zhang X, Cheng X. Structural basis for human PRDM9 action at recombination hot spots. Genes & Development. 30: 257-65. PMID 26833727 DOI: 10.1101/gad.274928.115  0.48
2015 Horton JR, Engstrom A, Zoeller EL, Liu X, Shanks JR, Zhang X, Johns MA, Vertino PM, Fu H, Cheng X. Characterization of a linked Jumonji domain of the KDM5/JARID1 family of histone H3 lysine 4 demethylases. The Journal of Biological Chemistry. PMID 26645689 DOI: 10.1074/jbc.M115.698449  0.48
2015 Hashimoto H, Pais JE, Dai N, Corrêa IR, Zhang X, Zheng Y, Cheng X. Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA. Nucleic Acids Research. PMID 26323320 DOI: 10.1093/nar/gkv870  0.48
2015 Hashimoto H, Zhang X, Vertino PM, Cheng X. The Mechanisms of Generation, Recognition, and Erasure of DNA 5-Methylcytosine and Thymine Oxidations. The Journal of Biological Chemistry. 290: 20723-33. PMID 26152719 DOI: 10.1074/jbc.R115.656884  0.48
2015 Horton JR, Zhang X, Blumenthal RM, Cheng X. Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression. Nucleic Acids Research. 43: 4296-308. PMID 25845600 DOI: 10.1093/nar/gkv251  0.48
2014 Horton JR, Wang H, Mabuchi MY, Zhang X, Roberts RJ, Zheng Y, Wilson GG, Cheng X. Modification-dependent restriction endonuclease, MspJI, flips 5-methylcytosine out of the DNA helix. Nucleic Acids Research. 42: 12092-101. PMID 25262349 DOI: 10.1093/nar/gku871  0.48
2014 Hashimoto H, Olanrewaju YO, Zheng Y, Wilson GG, Zhang X, Cheng X. Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence. Genes & Development. 28: 2304-13. PMID 25258363 DOI: 10.1101/gad.250746.114  0.48
2014 Hong S, Hashimoto H, Kow YW, Zhang X, Cheng X. The carboxy-terminal domain of ROS1 is essential for 5-methylcytosine DNA glycosylase activity. Journal of Molecular Biology. 426: 3703-12. PMID 25240767 DOI: 10.1016/j.jmb.2014.09.010  0.48
2014 Kao TH, Liao HF, Wolf D, Tai KY, Chuang CY, Lee HS, Kuo HC, Hata K, Zhang X, Cheng X, Goff SP, Ooi SK, Bestor TH, Lin SP. Ectopic DNMT3L triggers assembly of a repressive complex for retroviral silencing in somatic cells. Journal of Virology. 88: 10680-95. PMID 24991018 DOI: 10.1128/JVI.01176-14  0.48
2014 Horton JR, Borgaro JG, Griggs RM, Quimby A, Guan S, Zhang X, Wilson GG, Zheng Y, Zhu Z, Cheng X. Structure of 5-hydroxymethylcytosine-specific restriction enzyme, AbaSI, in complex with DNA. Nucleic Acids Research. 42: 7947-59. PMID 24895434 DOI: 10.1093/nar/gku497  0.48
2014 Horton JR, Nugent RL, Li A, Mabuchi MY, Fomenkov A, Cohen-Karni D, Griggs RM, Zhang X, Wilson GG, Zheng Y, Xu SY, Cheng X. Structure and mutagenesis of the DNA modification-dependent restriction endonuclease AspBHI. Scientific Reports. 4: 4246. PMID 24604015 DOI: 10.1038/srep04246  0.48
2014 Liu Y, Olanrewaju YO, Zheng Y, Hashimoto H, Blumenthal RM, Zhang X, Cheng X. Structural basis for Klf4 recognition of methylated DNA. Nucleic Acids Research. 42: 4859-67. PMID 24520114 DOI: 10.1093/nar/gku134  0.48
2014 Hashimoto H, Pais JE, Zhang X, Saleh L, Fu ZQ, Dai N, Corrêa IR, Zheng Y, Cheng X. Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA. Nature. 506: 391-5. PMID 24390346 DOI: 10.1038/nature12905  0.48
2014 Valente S, Liu Y, Schnekenburger M, Zwergel C, Cosconati S, Gros C, Tardugno M, Labella D, Florean C, Minden S, Hashimoto H, Chang Y, Zhang X, Kirsch G, Novellino E, ... ... Cheng X, et al. Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells. Journal of Medicinal Chemistry. 57: 701-13. PMID 24387159 DOI: 10.1021/jm4012627  0.48
2013 Liu Y, Olanrewaju YO, Zhang X, Cheng X. DNA recognition of 5-carboxylcytosine by a Zfp57 mutant at an atomic resolution of 0.97 Å. Biochemistry. 52: 9310-7. PMID 24236546 DOI: 10.1021/bi401360n  0.48
2013 Hashimoto H, Zhang X, Cheng X. Activity and crystal structure of human thymine DNA glycosylase mutant N140A with 5-carboxylcytosine DNA at low pH. Dna Repair. 12: 535-40. PMID 23680598 DOI: 10.1016/j.dnarep.2013.04.003  0.48
2013 Liu Y, Zhang X, Blumenthal RM, Cheng X. A common mode of recognition for methylated CpG. Trends in Biochemical Sciences. 38: 177-83. PMID 23352388 DOI: 10.1016/j.tibs.2012.12.005  0.48
2013 Hashimoto H, Zhang X, Cheng X. Selective excision of 5-carboxylcytosine by a thymine DNA glycosylase mutant. Journal of Molecular Biology. 425: 971-6. PMID 23337108 DOI: 10.1016/j.jmb.2013.01.013  0.48
2012 Liu Y, Toh H, Sasaki H, Zhang X, Cheng X. An atomic model of Zfp57 recognition of CpG methylation within a specific DNA sequence. Genes & Development. 26: 2374-9. PMID 23059534 DOI: 10.1101/gad.202200.112  0.48
2012 Hashimoto H, Hong S, Bhagwat AS, Zhang X, Cheng X. Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylation. Nucleic Acids Research. 40: 10203-14. PMID 22962365 DOI: 10.1093/nar/gks845  0.48
2012 Horton JR, Mabuchi MY, Cohen-Karni D, Zhang X, Griggs RM, Samaranayake M, Roberts RJ, Zheng Y, Cheng X. Structure and cleavage activity of the tetrameric MspJI DNA modification-dependent restriction endonuclease. Nucleic Acids Research. 40: 9763-73. PMID 22848107 DOI: 10.1093/nar/gks719  0.48
2012 Hashimoto H, Zhang X, Cheng X. Excision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: structural basis and implications for active DNA demethylation. Nucleic Acids Research. 40: 8276-84. PMID 22740654 DOI: 10.1093/nar/gks628  0.48
2012 Hashimoto H, Liu Y, Upadhyay AK, Chang Y, Howerton SB, Vertino PM, Zhang X, Cheng X. Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation. Nucleic Acids Research. 40: 4841-9. PMID 22362737 DOI: 10.1093/nar/gks155  0.48
2008 Jurkowska RZ, Anspach N, Urbanke C, Jia D, Reinhardt R, Nellen W, Cheng X, Jeltsch A. Formation of nucleoprotein filaments by mammalian DNA methyltransferase Dnmt3a in complex with regulator Dnmt3L. Nucleic Acids Research. 36: 6656-63. PMID 18945701 DOI: 10.1093/nar/gkn747  0.48
2008 Subramanian K, Jia D, Kapoor-Vazirani P, Powell DR, Collins RE, Sharma D, Peng J, Cheng X, Vertino PM. Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase. Molecular Cell. 30: 336-47. PMID 18471979 DOI: 10.1016/j.molcel.2008.03.022  0.48
2008 Dhayalan A, Jurkowski TP, Laser H, Reinhardt R, Jia D, Cheng X, Jeltsch A. Mapping of protein-protein interaction sites by the 'absence of interference' approach. Journal of Molecular Biology. 376: 1091-9. PMID 18191145 DOI: 10.1016/j.jmb.2007.12.032  0.48
2007 Jia D, Jurkowska RZ, Zhang X, Jeltsch A, Cheng X. Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation. Nature. 449: 248-51. PMID 17713477 DOI: 10.1038/nature06146  0.48
2007 Ooi SK, Qiu C, Bernstein E, Li K, Jia D, Yang Z, Erdjument-Bromage H, Tempst P, Lin SP, Allis CD, Cheng X, Bestor TH. DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature. 448: 714-7. PMID 17687327 DOI: 10.1038/nature05987  0.48
2005 Collins RE, Tachibana M, Tamaru H, Smith KM, Jia D, Zhang X, Selker EU, Shinkai Y, Cheng X. In vitro and in vivo analyses of a Phe/Tyr switch controlling product specificity of histone lysine methyltransferases. The Journal of Biological Chemistry. 280: 5563-70. PMID 15590646 DOI: 10.1074/jbc.M410483200  0.48
Low-probability matches
2020 Liu H, Mei FC, Yang W, Wang H, Wong E, Cai J, Toth E, Luo P, Li YM, Zhang W, Cheng X. Epac1 inhibition ameliorates pathological angiogenesis through coordinated activation of Notch and suppression of VEGF signaling. Science Advances. 6: eaay3566. PMID 31911948 DOI: 10.1126/sciadv.aay3566  0.04
2019 Wu X, Liu S, Sagum C, Chen J, Singh R, Chaturvedi A, Horton JR, Kashyap TR, Fushman D, Cheng X, Bedford MT, Wang B. Crosstalk between Lys63- and Lys11-polyubiquitin signaling at DNA damage sites is driven by Cezanne. Genes & Development. PMID 31699778 DOI: 10.1101/gad.332395.119  0.04
2019 Zoeller EL, Pedro B, Konen J, Dwivedi B, Rupji M, Sundararaman N, Wang L, Horton JR, Zhong C, Barwick BG, Cheng X, Martinez ED, Torres MP, Kowalski J, Marcus AI, et al. Genetic heterogeneity within collective invasion packs drives leader and follower cell phenotypes. Journal of Cell Science. PMID 31515279 DOI: 10.1242/jcs.231514  0.04
2019 Milite C, Feoli A, Horton JR, Rescigno D, Cipriano A, Pisapia V, Viviano M, Pepe G, Amendola G, Novellino E, Cosconati S, Cheng X, Castellano S, Sbardella G. Discovery of a novel chemotype of histone lysine methyltransferase EHMT1/2 (GLP/G9a) inhibitors: rational design, synthesis, biological evaluation and co-crystal structure. Journal of Medicinal Chemistry. PMID 30753076 DOI: 10.1021/acs.jmedchem.8b02008  0.04
2018 Wu L, Cao J, Cai WL, Lang SM, Horton JR, Jansen DJ, Liu ZZ, Chen JF, Zhang M, Mott BT, Pohida K, Rai G, Kales SC, Henderson MJ, Hu X, ... ... Cheng X, et al. KDM5 histone demethylases repress immune response via suppression of STING. Plos Biology. 16: e2006134. PMID 30080846 DOI: 10.1371/journal.pbio.2006134  0.04
2017 Yang W, Mei FC, Cheng X. EPAC1 regulates endothelial annexin A2 cell surface translocation and plasminogen activation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 29217666 DOI: 10.1096/fj.201701027R  0.04
2017 Li X, Huang K, Zhang Q, Zhou J, Sun H, Tang F, Zhou H, Hu T, Wang S, Jia Y, Yang R, Chen Y, Cheng X, Lv W, Wu L, et al. Genome-wide association study identifies four SNPs associated with response to platinum-based neoadjuvant chemotherapy for cervical cancer. Scientific Reports. 7: 41103. PMID 28120872 DOI: 10.1038/srep41103  0.04
2015 Pais JE, Dai N, Tamanaha E, Vaisvila R, Fomenkov AI, Bitinaite J, Sun Z, Guan S, Corrêa IR, Noren CJ, Cheng X, Roberts RJ, Zheng Y, Saleh L. Biochemical characterization of a Naegleria TET-like oxygenase and its application in single molecule sequencing of 5-methylcytosine. Proceedings of the National Academy of Sciences of the United States of America. 112: 4316-21. PMID 25831492 DOI: 10.1073/pnas.1417939112  0.04
2015 Daugherty AB, Horton JR, Cheng X, Lutz S. STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF CIRCULAR PERMUTATION ON THE ACTIVE SITE OF OLD YELLOW ENZYME. Acs Catalysis. 5: 892-899. PMID 25692074 DOI: 10.1021/cs501702k  0.04
2014 Fu Y, Wang X, Cheng X, Ye F, Xie X, Lu W. Clinicopathological and biological significance of aberrant activation of glycogen synthase kinase-3 in ovarian cancer. Oncotargets and Therapy. 7: 1159-68. PMID 25028561 DOI: 10.2147/OTT.S62158  0.04
2013 Cheng X, Blumenthal RM. Response to mackay et Al. Trends in Biochemical Sciences. 38: 423. PMID 23992946 DOI: 10.1016/j.tibs.2013.06.010  0.04
2013 Shi Y, Li L, Hu Z, Li S, Wang S, Liu J, Wu C, He L, Zhou J, Li Z, Hu T, Chen Y, Jia Y, Wang S, Wu L, ... Cheng X, et al. A genome-wide association study identifies two new cervical cancer susceptibility loci at 4q12 and 17q12. Nature Genetics. 45: 918-22. PMID 23817570 DOI: 10.1038/ng.2687  0.04
2013 Liu X, Bennett RL, Cheng X, Byrne M, Reinhard MK, May WS. PKR regulates proliferation, differentiation, and survival of murine hematopoietic stem/progenitor cells. Blood. 121: 3364-74. PMID 23403623 DOI: 10.1182/blood-2012-09-456400  0.04
2013 Sun Z, Terragni J, Jolyon T, Borgaro JG, Liu Y, Yu L, Guan S, Wang H, Sun D, Cheng X, Zhu Z, Pradhan S, Zheng Y. High-resolution enzymatic mapping of genomic 5-hydroxymethylcytosine in mouse embryonic stem cells. Cell Reports. 3: 567-76. PMID 23352666 DOI: 10.1016/j.celrep.2013.01.001  0.04
2012 Hu T, Li S, Chen Y, Shen J, Li X, Huang K, Yang R, Wu L, Chen Z, Jia Y, Wang S, Cheng X, Han X, Lin Z, Xing H, et al. Matched-case comparison of neoadjuvant chemotherapy in patients with FIGO stage IB1-IIB cervical cancer to establish selection criteria. European Journal of Cancer (Oxford, England : 1990). 48: 2353-60. PMID 22503395 DOI: 10.1016/j.ejca.2012.03.015  0.04
2020 Cun Y, Dou C, Tian S, Li M, Zhu Y, Cheng X, Chen W. Traditional and bionic dynamic hip screw fixation for the treatment of intertrochanteric fracture: a finite element analysis. International Orthopaedics. PMID 31927636 DOI: 10.1007/s00264-019-04478-9  0.01
2020 Liu W, Ha Y, Xia F, Zhu S, Li Y, Shi S, Mei FC, Merkley K, Vizzeri G, Motamedi M, Cheng X, Liu H, Zhang W. Neuronal Epac1 mediates retinal neurodegeneration in mouse models of ocular hypertension. The Journal of Experimental Medicine. 217. PMID 31918438 DOI: 10.1084/jem.20190930  0.01
2020 Berkey SC, Herrera JJ, Odem MA, Rahman S, Cheruvu SS, Cheng X, Walters ET, Dessauer CW, Bavencoffe AG. EPAC1 and EPAC2 promote nociceptor hyperactivity associated with chronic pain after spinal cord injury. Neurobiology of Pain (Cambridge, Mass.). 7: 100040. PMID 31890991 DOI: 10.1016/j.ynpai.2019.100040  0.01
2019 White MA, Tsalkova T, Mei FC, Cheng X. Conformational States of Exchange Protein Directly Activated by cAMP (EPAC1) Revealed by Ensemble Modeling and Integrative Structural Biology. Cells. 9. PMID 31877746 DOI: 10.3390/cells9010035  0.01
2019 Yang S, Chen T, Huang L, Xu S, Cao Z, Zhang S, Xu J, Li Y, Yue Y, Lu W, Cheng X, Xie X. High-Risk Human Papillomavirus E7 Maintains Stemness Via APH1B In Cervical Cancer Stem-Cell Like Cells. Cancer Management and Research. 11: 9541-9552. PMID 31814758 DOI: 10.2147/CMAR.S194239  0.01
2019 Ahmed A, Boulton S, Shao H, Akimoto M, Natarajan A, Cheng X, Melacini G. Recent Advances in EPAC-Targeted Therapies: A Biophysical Perspective. Cells. 8. PMID 31752286 DOI: 10.3390/cells8111462  0.01
2019 Zhao T, Zhai C, Song H, Wu Y, Ge C, Zhang Y, Xu H, Chi Z, Chu H, Shi W, Cheng X, Li X, Ma M, Xu M, Hu J, et al. Methamphetamine-Induced Cognitive Deficits and Psychiatric Symptoms Are Associated with Serum Markers of Liver Damage. Neurotoxicity Research. PMID 31691188 DOI: 10.1007/s12640-019-00115-w  0.01
2019 Zhang L, Zhou Q, Qiu Q, Hou L, Wu M, Li J, Li X, Lu B, Cheng X, Liu P, Lu W, Lu Y. CircPLEKHM3 acts as a tumor suppressor through regulation of the miR-9/BRCA1/DNAJB6/KLF4/AKT1 axis in ovarian cancer. Molecular Cancer. 18: 144. PMID 31623606 DOI: 10.1186/s12943-019-1080-5  0.01
2019 Dong C, Liu S, Cheng X, Wang Q, Jiang S, Wang G. Design, synthesis, and preliminary biological evaluation of catalpol propionates as antiaging drugs. Bmc Chemistry. 13: 109. PMID 31453572 DOI: 10.1186/s13065-019-0626-3  0.01
2019 Li Y, Ren Z, Yuan X, Chen M, Cao W, Cheng Q, Jin Z, Cheng X, Zhang C, Yang J, Fang D. Reflection phase dispersion editing generates wideband invisible acoustic Huygens's metasurface. The Journal of the Acoustical Society of America. 146: 166. PMID 31370652 DOI: 10.1121/1.5116012  0.01
2019 Cheng X, Li Y, He Y. [Preparation and chromatographic evaluation of zwitterionic stationary phases with controllable ratios of positively and negatively charged groups]. SE Pu = Chinese Journal of Chromatography. 37: 683-691. PMID 31271007 DOI: 10.3724/SP.J.1123.2019.01038  0.01
2019 Barella LF, Rossi M, Zhu L, Cui Y, Mei FC, Cheng X, Chen W, Gurevich VV, Wess J. β-Cell-intrinsic β-arrestin 1 signaling enhances sulfonylurea-induced insulin secretion. The Journal of Clinical Investigation. 130. PMID 31184597 DOI: 10.1172/JCI126309  0.01
2019 Wu Q, Wu Q, Xu J, Cheng X, Wang X, Lu W, Li X. Efficacy of hyperthermic intraperitoneal chemotherapy in patients with epithelial ovarian cancer: a meta-analysis. International Journal of Hyperthermia : the Official Journal of European Society For Hyperthermic Oncology, North American Hyperthermia Group. 36: 562-572. PMID 31137989 DOI: 10.1080/02656736.2019.1612101  0.01
2019 Boulton S, Selvaratnam R, Ahmed R, Van K, Cheng X, Melacini G. Mechanisms of Specific versus Nonspecific Interactions of Aggregation-Prone Inhibitors and Attenuators. Journal of Medicinal Chemistry. PMID 31074269 DOI: 10.1021/acs.jmedchem.9b00258  0.01
2019 Sun Y, Jing Y, Huang M, Ma J, Peng X, Wang J, Li G, Cheng X. The PD-1/PD-Ls pathway is up-regulated during the suppression of experimental autoimmune encephalomyelitis treated by Astragalus polysaccharides. Journal of Neuroimmunology. 332: 78-90. PMID 30981049 DOI: 10.1016/j.jneuroim.2019.03.019  0.01
2019 Cheng X, Jia Q, Yu Y, Cao Y. Imipenem-resistant ceftazidime-susceptible Pseudomonas aeruginosa isolated from prosthetic joint infection in China. Infectious Diseases (London, England). 1-3. PMID 30646807 DOI: 10.1080/23744235.2018.1543946  0.01
2018 Li X, Xu Y, Liu Y, Cheng X, Wang X, Lu W, Xie X. The management of hydatidiform mole with lung nodule: a retrospective analysis in 53 patients. Journal of Gynecologic Oncology. PMID 30740949 DOI: 10.3802/jgo.2019.30.e16  0.01
2018 Zhai C, Cui M, Cheng X, Ao X, Zhao T, Wu W, Shao Q, Ge D, Song H, Qi F, Ling Q, Ma M, Xu M, Jiao D. Vitamin B12 Levels in Methamphetamine Addicts. Frontiers in Behavioral Neuroscience. 12: 320. PMID 30618670 DOI: 10.3389/fnbeh.2018.00320  0.01
2018 Gorshkov K, Sima N, Sun W, Lu B, Huang W, Travers J, Klumpp-Thomas C, Michael SG, Xu T, Huang R, Lee EM, Cheng X, Zheng W. Quantitative Chemotherapeutic Profiling of Gynecologic Cancer Cell Lines Using Approved Drugs and Bioactive Compounds. Translational Oncology. 12: 441-452. PMID 30576957 DOI: 10.1016/j.tranon.2018.11.016  0.01
2018 Xu S, Yue Y, Zhang S, Zhou C, Cheng X, Xie X, Wang X, Lu W. STON2 negatively modulates stem-like properties in ovarian cancer cells via DNMT1/MUC1 pathway. Journal of Experimental & Clinical Cancer Research : Cr. 37: 305. PMID 30518424 DOI: 10.1186/s13046-018-0977-y  0.01
2018 Gao S, Lu J, Cheng X, Gu Z, Liao Q, Du Z. Heterologous Replicase from Cucumoviruses can Replicate Viral RNAs, but is Defective in Transcribing Subgenomic RNA4A or Facilitating Viral Movement. Viruses. 10. PMID 30373277 DOI: 10.3390/v10110590  0.01
2018 Cherezova A, Tomilin V, Buncha V, Zaika O, Ortiz PA, Mei F, Cheng X, Mamenko M, Pochynyuk O. Urinary concentrating defect in mice lacking Epac1 or Epac2. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201800435R. PMID 30252533 DOI: 10.1096/fj.201800435R  0.01
2018 Chen J, Yuan X, Chen M, Cheng X, Zhang A, Peng G, Song WL, Fang D. Ultra-broadband 3D printed radial perfectly symmetric gradient honeycomb all-dielectric dual-directional lightweight planar Luneburg lens. Acs Applied Materials & Interfaces. PMID 30212180 DOI: 10.1021/acsami.8b11239  0.01
2018 Liu S, Li S, Wei N, Chang W, Hu P, Cheng X, Wang L, Chen W. Application of multidimensional interpolation on nonhomogeneous cancellous bone. Medicine. 97: e12224. PMID 30200144 DOI: 10.1097/MD.0000000000012224  0.01
2018 Shen Y, Liang Y, Cheng X, Lu W, Xie X, Wan X. Ovarian fibroma/fibrothecoma with elevated serum CA125 level: A cohort of 66 cases. Medicine. 97: e11926. PMID 30142807 DOI: 10.1097/MD.0000000000011926  0.01
2018 Yu C, Wang J, Lu W, Xie X, Cheng X, Li X. Analysis of adnexal mass managed during cesarean section. Advances in Clinical and Experimental Medicine : Official Organ Wroclaw Medical University. PMID 30085429 DOI: 10.17219/acem/77099  0.01
2018 Sima N, Sun W, Gorshkov K, Shen M, Huang W, Zhu W, Xie X, Zheng W, Cheng X. Small Molecules Identified from a Quantitative Drug Combinational Screen Resensitize Cisplatin's Response in Drug-Resistant Ovarian Cancer Cells. Translational Oncology. 11: 1053-1064. PMID 29982103 DOI: 10.1016/j.tranon.2018.06.002  0.01
2018 Wu T, Ren X, Cui Y, Cheng X, Peng S, Hou Z, Han Y. Biomechanical study of three kinds of internal fixation for the treatment of sacroiliac joint disruption using biomechanical test and finite element analysis. Journal of Orthopaedic Surgery and Research. 13: 152. PMID 29914519 DOI: 10.1186/s13018-018-0858-2  0.01
2018 Nash CA, Brown LM, Malik S, Cheng X, Smrcka AV. Compartmentalized cyclic nucleotides have opposing effects on regulation of hypertrophic phospholipase Cε signaling in cardiac myocytes. Journal of Molecular and Cellular Cardiology. PMID 29885334 DOI: 10.1016/j.yjmcc.2018.06.002  0.01
2018 Su S, Wu G, Cheng X, Fan J, Peng J, Su H, Xu Z, Cao M, Long Z, Hao Y, Li G, Li S, Hai C, Wang X. Oleanolic acid attenuates PCBs-induced adiposity and insulin resistance via HNF1b-mediated regulation of redox and PPARγ signaling. Free Radical Biology & Medicine. PMID 29879443 DOI: 10.1016/j.freeradbiomed.2018.06.003  0.01
2018 Su S, Cao M, Wu G, Long Z, Cheng X, Fan J, Xu Z, Su H, Hao Y, Li G, Peng J, Li S, Wang X. Hordenine protects against hyperglycemia-associated renal complications in streptozotocin-induced diabetic mice. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 104: 315-324. PMID 29775900 DOI: 10.1016/j.biopha.2018.05.036  0.01
2018 Wang H, Cheng X, Ye J, Xu X, Hong Y, Sui L, You Z, Xie X. Distribution of human papilloma virus genotype prevalence in invasive cervical carcinomas and precancerous lesions in the Yangtze River Delta area, China. Bmc Cancer. 18: 487. PMID 29703167 DOI: 10.1186/s12885-018-4330-9  0.01
2018 Robichaux WG, Cheng X. Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development. Physiological Reviews. 98: 919-1053. PMID 29537337 DOI: 10.1152/physrev.00025.2017  0.01
2018 Cui Y, Hu P, Wei N, Cheng X, Chang W, Chen W. Finite Element Study of Implant Subsidence and Medial Tilt in Agility Ankle Replacement. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 24: 1124-1131. PMID 29472522  0.01
2018 Singhmar P, Huo X, Li Y, Dougherty PM, Mei F, Cheng X, Heijnen CJ, Kavelaars A. An Orally Active Epac Inhibitor Reverses Mechanical Allodynia and Loss of Intraepidermal Nerve Fibers \iIn A Mouse Model of Chemotherapy-Induced Peripheral Neuropathy. Pain. PMID 29369966 DOI: 10.1097/j.pain.0000000000001160  0.01
2017 Sonawane YA, Zhu Y, Garrison JC, Ezell EL, Zahid M, Cheng X, Natarajan A. Structure-Activity Relationship Studies with Tetrahydroquinoline Analogs as EPAC Inhibitors. Acs Medicinal Chemistry Letters. 8: 1183-1187. PMID 29375750 DOI: 10.1021/acsmedchemlett.7b00358  0.01
2017 Wang X, Fang Z, Wang A, Luo C, Cheng X, Lu M. Lithium Suppresses Hedgehog Signaling via Promoting ITCH E3 Ligase Activity and Gli1-SUFU Interaction in PDA Cells. Frontiers in Pharmacology. 8: 820. PMID 29249966 DOI: 10.3389/fphar.2017.00820  0.01
2017 Youngblood B, Hale JS, Kissick HT, Ahn E, Xu X, Wieland A, Araki K, West EE, Ghoneim HE, Fan Y, Dogra P, Davis CW, Konieczny BT, Antia R, Cheng X, et al. Effector CD8 T cells dedifferentiate into long-lived memory cells. Nature. PMID 29236683 DOI: 10.1038/nature25144  0.01
2017 Peng Q, Qin J, Zhang Y, Cheng X, Wang X, Lu W, Xie X, Zhang S. Autophagy maintains the stemness of ovarian cancer stem cells by FOXA2. Journal of Experimental & Clinical Cancer Research : Cr. 36: 171. PMID 29187221 DOI: 10.1186/s13046-017-0644-8  0.01
2017 Liu Z, Zhu Y, Chen H, Wang P, Mei FC, Ye N, Cheng X, Zhou J. Structure-activity relationships of 2-substituted phenyl-N-phenyl-2-oxoacetohydrazonoyl cyanides as novel antagonists of exchange proteins directly activated by cAMP (EPACs). Bioorganic & Medicinal Chemistry Letters. PMID 29100797 DOI: 10.1016/j.bmcl.2017.10.056  0.01
2017 Yu Y, Lu B, Lu W, Li S, Li X, Wang X, Wan X, Chen Y, Feng S, Jia Y, Yang R, Tang F, Li X, Zhang S, Wang X, ... ... Cheng X, et al. Whole-exome sequencing reveals genetic variants in ERC1 and KCNG4 associated with complete hydatidiform mole in Chinese Han women. Oncotarget. 8: 75264-75271. PMID 29088863 DOI: 10.18632/oncotarget.20769  0.01
2017 Lee CC, Peng SH, Shen L, Lee CF, Du TH, Kang ML, Xu GL, Upadhyay AK, Cheng X, Yan YT, Zhang Y, Juan LJ. The Role of N-α-acetyltransferase 10 Protein in DNA Methylation and Genomic Imprinting. Molecular Cell. PMID 28943313 DOI: 10.1016/j.molcel.2017.08.025  0.01
2017 Zhu Y, Mei F, Luo P, Cheng X. A cell-based, quantitative and isoform-specific assay for exchange proteins directly activated by cAMP. Scientific Reports. 7: 6200. PMID 28740152 DOI: 10.1038/s41598-017-06432-4  0.01
2017 Yang P, Wang Y, Hoang D, Tinkham M, Patel A, Sun MA, Wolf G, Baker M, Chien HC, Lai KN, Cheng X, Shen CJ, Macfarlan TS. A placental growth factor is silenced in mouse embryos by the zinc finger protein ZFP568. Science (New York, N.Y.). 356: 757-759. PMID 28522536 DOI: 10.1126/science.aah6895  0.01
2017 Wang X, Luo C, Cheng X, Lu M. Lithium and an EPAC-specific inhibitor ESI-09 synergistically suppress pancreatic cancer cell proliferation and survival. Acta Biochimica Et Biophysica Sinica. 1-8. PMID 28475672 DOI: 10.1093/abbs/gmx045  0.01
2017 Head PE, Zhang H, Bastien AJ, Koyen AE, Withers AE, Daddacha WB, Cheng X, Yu DS. Sirtuin 2 mutations in human cancers impair its function in genome maintenance. The Journal of Biological Chemistry. PMID 28461331 DOI: 10.1074/jbc.M116.772566  0.01
2017 Ye N, Zhu Y, Liu Z, Mei FC, Chen H, Wang P, Cheng X, Zhou J. Identification of novel 2-(benzo[d]isoxazol-3-yl)-2-oxo-N-phenylacetohydrazonoyl cyanide analoguesas potent EPAC antagonists. European Journal of Medicinal Chemistry. 134: 62-71. PMID 28399451 DOI: 10.1016/j.ejmech.2017.04.001  0.01
2017 Chen T, Dong B, Chen K, Zhao F, Cheng X, Ma C, Lee S, Zhang P, Kang SH, Ha JW, Xu W, Fang N. Optical Super-Resolution Imaging of Surface Reactions. Chemical Reviews. PMID 28306243 DOI: 10.1021/acs.chemrev.6b00673  0.01
2017 Wang P, Liu Z, Chen H, Ye N, Cheng X, Zhou J. Exchange proteins directly activated by cAMP (EPACs): Emerging therapeutic targets. Bioorganic & Medicinal Chemistry Letters. PMID 28283242 DOI: 10.1016/j.bmcl.2017.02.065  0.01
2017 Hong D, Liu J, Hu Y, Lu X, Li B, Li Y, Hu D, Lu W, Xie X, Cheng X. Viral E6 is overexpressed via high viral load in invasive cervical cancer with episomal HPV16. Bmc Cancer. 17: 136. PMID 28202002 DOI: 10.1186/s12885-017-3124-9  0.01
2017 Muñoz-Llancao P, de Gregorio C, Las Heras M, Meinohl C, Noorman K, Boddeke E, Cheng X, Lezoualc'h F, Schmidt M, Gonzalez-Billault C. Microtubule-regulating proteins and cAMP-dependent signaling in neuroblastoma differentiation. Cytoskeleton (Hoboken, N.J.). PMID 28164467 DOI: 10.1002/cm.21355  0.01
2016 Chen X, Xu J, Ye J, Cheng X, Xie X, Lyu W. [Expression of miR-let-7e-3p in cervical intraepithelial neoplasm and cervix carcinoma and its clinical significance]. Zhejiang Da Xue Xue Bao. Yi Xue Ban = Journal of Zhejiang University. Medical Sciences. 45: 342-348. PMID 27868406  0.01
2016 Wang H, Robichaux WG, Wang Z, Mei FC, Cai M, Du G, Chen J, Cheng X. Inhibition of Epac1 suppresses mitochondrial fission and reduces neointima formation induced by vascular injury. Scientific Reports. 6: 36552. PMID 27830723 DOI: 10.1038/srep36552  0.01
2016 Hong S, Cheng X. DNA Base Flipping: A General Mechanism for Writing, Reading, and Erasing DNA Modifications. Advances in Experimental Medicine and Biology. 945: 321-341. PMID 27826845 DOI: 10.1007/978-3-319-43624-1_14  0.01
2016 Baameur F, Singhmar P, Zhou Y, Hancock JF, Cheng X, Heijnen CJ, Kavelaars A. Epac1 interacts with importin β1 and controls neurite outgrowth independently of cAMP and Rap1. Scientific Reports. 6: 36370. PMID 27808165 DOI: 10.1038/srep36370  0.01
2016 Liao G, Gao B, Gao Y, Yang X, Cheng X, Ou Y. Phycocyanin Inhibits Tumorigenic Potential of Pancreatic Cancer Cells: Role of Apoptosis and Autophagy. Scientific Reports. 6: 34564. PMID 27694919 DOI: 10.1038/srep34564  0.01
2016 Huang Y, Li Y, Wang FF, Lv W, Xie X, Cheng X. Over-Expressed miR-224 Promotes the Progression of Cervical Cancer via Targeting RASSF8. Plos One. 11: e0162378. PMID 27626930 DOI: 10.1371/journal.pone.0162378  0.01
2016 Wan G, Ruan L, Yin Y, Yang T, Ge M, Cheng X. Effects of silver nanoparticles in combination with antibiotics on the resistant bacteria Acinetobacter baumannii. International Journal of Nanomedicine. 11: 3789-800. PMID 27574420 DOI: 10.2147/IJN.S104166  0.01
2016 Hao Z, Lü W, Cheng X, Zhou C. Immunohistochemical Expression and Clinical Significance of Wnt11 and BCL2A1 in Complete Moles. Analytical and Quantitative Cytopathology and Histopathology. 38: 79-86. PMID 27386628  0.01
2016 Hu Y, Robichaux WG, Mei FC, Kim ER, Wang H, Tong Q, Jin J, Xu M, Chen J, Cheng X. Role of exchange protein directly activated by cAMP isoform 1 in energy homeostasis: regulation of leptin expression and secretion in white adipose tissue. Molecular and Cellular Biology. PMID 27381457 DOI: 10.1128/MCB.01034-15  0.01
2016 Xu J, Wan X, Chen X, Fang Y, Cheng X, Xie X, Lu W. miR-2861 acts as a tumor suppressor via targeting EGFR/AKT2/CCND1 pathway in cervical cancer induced by human papillomavirus virus 16 E6. Scientific Reports. 6: 28968. PMID 27364926 DOI: 10.1038/srep28968  0.01
2016 Jansen SR, Poppinga WJ, de Jager W, Lezoualc'h F, Cheng X, Wieland T, Yarwood SJ, Gosens R, Schmidt M. Epac1 links prostaglandin E2 to β-catenin-dependent transcription during epithelial-to-mesenchymal transition. Oncotarget. PMID 27344171 DOI: 10.18632/oncotarget.10128  0.01
2016 Li B, Shi H, Wang F, Hong D, Lv W, Xie X, Cheng X. Expression of E-, P- and N-Cadherin and Its Clinical Significance in Cervical Squamous Cell Carcinoma and Precancerous Lesions. Plos One. 11: e0155910. PMID 27223886 DOI: 10.1371/journal.pone.0155910  0.01
2016 Zou J, Cao Z, Zhang J, Chen T, Yang S, Huang Y, Hong D, Li Y, Chen X, Wang X, Cheng X, Lu W, Xie X. Variants in human papillomavirus receptor and associated genes are associated with type-specific HPV infection and lesion progression of the cervix. Oncotarget. PMID 27223085 DOI: 10.18632/oncotarget.9510  0.01
2016 Wild CT, Zhu Y, Na Y, Mei F, Ynalvez MA, Chen H, Cheng X, Zhou J. Functionalized N,N-Diphenylamines as Potent and Selective EPAC2 Inhibitors. Acs Medicinal Chemistry Letters. 7: 460-464. PMID 27190593 DOI: 10.1021/acsmedchemlett.5b00477  0.01
2016 Xu J, Fang Y, Wang X, Wang F, Tian Q, Li Y, Xie X, Cheng X, Lu W. CUL2 overexpression driven by CUL2/E2F1/miR-424 regulatory loop promotes HPV16 E7 induced cervical carcinogenesis. Oncotarget. PMID 27153550 DOI: 10.18632/oncotarget.9127  0.01
2016 Li S, Li X, Zhang Y, Zhou H, Tang F, Jia Y, Hu T, Sun H, Yang R, Chen Y, Cheng X, Lv W, Wu L, Zhou J, Wang S, et al. Development and validation of a surgical-pathologic staging and scoring system for cervical cancer. Oncotarget. PMID 27014971 DOI: 10.18632/oncotarget.8245  0.04
2016 Singhmar P, Huo X, Eijkelkamp N, Berciano SR, Baameur F, Mei FC, Zhu Y, Cheng X, Hawke D, Mayor F, Murga C, Heijnen CJ, Kavelaars A. Critical role for Epac1 in inflammatory pain controlled by GRK2-mediated phosphorylation of Epac1. Proceedings of the National Academy of Sciences of the United States of America. PMID 26929333 DOI: 10.1073/pnas.1516036113  0.01
2016 Gao Y, Liu C, Wan G, Wang X, Cheng X, Ou Y. Phycocyanin prevents methylglyoxal-induced mitochondrial-dependent apoptosis in INS-1 cells by Nrf2. Food & Function. PMID 26805012 DOI: 10.1039/c5fo01548k  0.01
2015 Cheng X, Feng Y. [Preparation and evaluation of N-acryloyltris (hydroxymethyl) aminomethane-bonded chromatographic stationary phase]. SE Pu = Chinese Journal of Chromatography / Zhongguo Hua Xue Hui. 33: 917-21. PMID 26753276  0.01
2015 Zeng Y, Yao B, Shin J, Lin L, Kim N, Song Q, Liu S, Su Y, Guo JU, Huang L, Wan J, Wu H, Qian J, Cheng X, Zhu H, et al. Lin28A Binds Active Promoters and Recruits Tet1 to Regulate Gene Expression. Molecular Cell. PMID 26711009 DOI: 10.1016/j.molcel.2015.11.020  0.01
2015 Liang Y, Lü B, Chen X, Qin J, Cheng X, Xie X, Lü W. Prognostic value of pathological response to neoadjuvant chemotherapy in bulky stage Ib2 and IIa cervical squamous cell cancer patients. Virchows Archiv : An International Journal of Pathology. PMID 26637198 DOI: 10.1007/s00428-015-1888-3  0.01
2015 Gao Y, Liao G, Xiang C, Yang X, Cheng X, Ou Y. Effects of Phycocyanin on INS-1 Pancreatic β-Cell Mediated by PI3K/Akt/FoxO1 signaling pathway. International Journal of Biological Macromolecules. PMID 26616456 DOI: 10.1016/j.ijbiomac.2015.11.054  0.01
2015 Cheng X. New hopes in the fight against cancer: a special issue on targeted anti-cancer drug discovery. Acta Biochimica Et Biophysica Sinica. PMID 26578705 DOI: 10.1093/abbs/gmv117  0.01
2015 Estève PO, Zhang G, Ponnaluri VK, Deepti K, Chin HG, Dai N, Sagum C, Black K, Corrêa IR, Bedford MT, Cheng X, Pradhan S. Binding of 14-3-3 reader proteins to phosphorylated DNMT1 facilitates aberrant DNA methylation and gene expression. Nucleic Acids Research. PMID 26553800 DOI: 10.1093/nar/gkv1162  0.01
2015 Almahariq M, Mei FC, Cheng X. The pleiotropic role of exchange protein directly activated by cAMP 1 (EPAC1) in cancer: implications for therapeutic intervention. Acta Biochimica Et Biophysica Sinica. PMID 26525949 DOI: 10.1093/abbs/gmv115  0.01
2015 Cheng X, Byrne M, Brown KD, Konopleva MY, Kornblau SM, Bennett RL, May WS. PKR inhibits the DNA damage response, and is associated with poor survival in AML and accelerated leukemia in NHD13 mice. Blood. 126: 1585-94. PMID 26202421 DOI: 10.1182/blood-2015-03-635227  0.01
2015 Li X, Pan Q, Wan X, Mao Y, Lu W, Xie X, Cheng X. Methylation-associated Has-miR-9 deregulation in paclitaxel- resistant epithelial ovarian carcinoma. Bmc Cancer. 15: 509. PMID 26152689 DOI: 10.1186/s12885-015-1509-1  0.01
2015 Ye N, Zhu Y, Chen H, Liu Z, Mei FC, Wild C, Chen H, Cheng X, Zhou J. Structure-Activity Relationship Studies of Substituted 2-(Isoxazol-3-yl)-2-oxo-N'-phenyl-acetohydrazonoyl Cyanide Analogues: Identification of Potent Exchange Proteins Directly Activated by cAMP (EPAC) Antagonists. Journal of Medicinal Chemistry. 58: 6033-47. PMID 26151319 DOI: 10.1021/acs.jmedchem.5b00635  0.01
2015 Banerjee U, Cheng X. Exchange protein directly activated by cAMP encoded by the mammalian rapgef3 gene: Structure, function and therapeutics. Gene. PMID 26119090 DOI: 10.1016/j.gene.2015.06.063  0.01
2015 Liu ZQ, Zheng W, Huang JF, Jin LQ, Jia DX, Zhou HY, Xu JM, Liao CJ, Cheng XP, Mao BX, Zheng YG. Improvement and characterization of a hyperthermophilic glucose isomerase from Thermoanaerobacter ethanolicus and its application in production of high fructose corn syrup. Journal of Industrial Microbiology & Biotechnology. 42: 1091-103. PMID 26077737 DOI: 10.1007/s10295-015-1639-0  0.01
2015 Schwede F, Chepurny OG, Kaufholz M, Bertinetti D, Leech CA, Cabrera O, Zhu Y, Mei F, Cheng X, Manning Fox JE, MacDonald PE, Genieser HG, Herberg FW, Holz GG. Rp-cAMPS Prodrugs Reveal the cAMP Dependence of First-Phase Glucose-Stimulated Insulin Secretion. Molecular Endocrinology (Baltimore, Md.). 29: 988-1005. PMID 26061564 DOI: 10.1210/me.2014-1330  0.01
2015 Fu Y, Chen C, Feng S, Cheng X, Wang X, Xie X, Lü W. Residual disease and risk factors in patients with high-grade cervical intraepithelial neoplasia and positive margins after initial conization. Therapeutics and Clinical Risk Management. 11: 851-6. PMID 26056463 DOI: 10.2147/TCRM.S81802  0.01
2015 Wang X, Shen C, Liu S, Gao C, Cheng X, Zhang F. New material of Longipteryx (Aves: Enantiornithes) from the Lower Cretaceous Yixian Formation of China with the first recognized avian tooth crenulations. Zootaxa. 3941: 565-78. PMID 25947529  0.01
2015 Zhou L, Yang L, Zeng X, Danzheng J, Zheng Q, Liu J, Liu F, Xin Y, Cheng X, Su M, Ma Y, Hao X. Transcriptional and proteomic analyses of two-component response regulators in multidrug-resistant Mycobacterium tuberculosis. International Journal of Antimicrobial Agents. 46: 73-81. PMID 25937537 DOI: 10.1016/j.ijantimicag.2015.02.018  0.01
2015 Alpay M, Backman LR, Cheng X, Dukel M, Kim WJ, Ai L, Brown KD. Oxidative stress shapes breast cancer phenotype through chronic activation of ATM-dependent signaling. Breast Cancer Research and Treatment. 151: 75-87. PMID 25862169 DOI: 10.1007/s10549-015-3368-5  0.01
2015 Zhu Y, Chen H, Boulton S, Mei F, Ye N, Melacini G, Zhou J, Cheng X. Biochemical and pharmacological characterizations of ESI-09 based EPAC inhibitors: defining the ESI-09 "therapeutic window". Scientific Reports. 5: 9344. PMID 25791905 DOI: 10.1038/srep09344  0.01
2015 Wang X, Lu M, Shi Y, Ou Y, Cheng X. Discovery of novel new Delhi metallo-β-lactamases-1 inhibitors by multistep virtual screening. Plos One. 10: e0118290. PMID 25734558 DOI: 10.1371/journal.pone.0118290  0.01
2015 Huang L, Xu S, Hu D, Lu W, Xie X, Cheng X. IQGAP1 Is Involved in Enhanced Aggressive Behavior of Epithelial Ovarian Cancer Stem Cell-Like Cells During Differentiation. International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. 25: 559-65. PMID 25675045 DOI: 10.1097/IGC.0000000000000394  0.01
2015 Myrick LK, Deng PY, Hashimoto H, Oh YM, Cho Y, Poidevin MJ, Suhl JA, Visootsak J, Cavalli V, Jin P, Cheng X, Warren ST, Klyachko VA. Independent role for presynaptic FMRP revealed by an FMR1 missense mutation associated with intellectual disability and seizures. Proceedings of the National Academy of Sciences of the United States of America. 112: 949-56. PMID 25561520 DOI: 10.1073/pnas.1423094112  0.01
2015 Myrick LK, Hashimoto H, Cheng X, Warren ST. Human FMRP contains an integral tandem Agenet (Tudor) and KH motif in the amino terminal domain. Human Molecular Genetics. 24: 1733-40. PMID 25416280 DOI: 10.1093/hmg/ddu586  0.01
2015 Almahariq M, Chao C, Mei FC, Hellmich MR, Patrikeev I, Motamedi M, Cheng X. Pharmacological inhibition and genetic knockdown of exchange protein directly activated by cAMP 1 reduce pancreatic cancer metastasis in vivo. Molecular Pharmacology. 87: 142-9. PMID 25385424 DOI: 10.1124/mol.114.095158  0.01
2015 Almahariq M, Mei FC, Wang H, Cao AT, Yao S, Soong L, Sun J, Cong Y, Chen J, Cheng X. Exchange protein directly activated by cAMP modulates regulatory T-cell-mediated immunosuppression. The Biochemical Journal. 465: 295-303. PMID 25339598 DOI: 10.1042/BJ20140952  0.01
2014 Yang X, Xu J, Cheng X, Xie X, Lü W. [Distribution of human papillomavirus genotypes in early-stadge cervical adenocarcinoma and its clinical significance]. Zhonghua Yi Xue Za Zhi. 94: 3583-5. PMID 25622839  0.01
2014 Qin J, Ying W, Cheng X, Wu X, Lu B, Liang Y, Wang X, Wan X, Xie X, Lu W. A well-circumscribed border with peripheral Doppler signal in sonographic image distinguishes epithelioid trophoblastic tumor from other gestational trophoblastic neoplasms. Plos One. 9: e112618. PMID 25396428 DOI: 10.1371/journal.pone.0112618  0.01
2014 Shen Y, Zhou J, Li Y, Ye F, Wan X, Lu W, Xie X, Cheng X. miR-375 mediated acquired chemo-resistance in cervical cancer by facilitating EMT. Plos One. 9: e109299. PMID 25330011 DOI: 10.1371/journal.pone.0109299  0.01
2014 Byrne M, Bennett RL, Cheng X, May WS. Progressive genomic instability in the Nup98-HoxD13 model of MDS correlates with loss of the PIG-A gene product. Neoplasia (New York, N.Y.). 16: 627-33. PMID 25220590 DOI: 10.1016/j.neo.2014.07.004  0.01
2014 Tian Q, Li Y, Wang F, Li Y, Xu J, Shen Y, Ye F, Wang X, Cheng X, Chen Y, Wan X, Lu W, Xie X. MicroRNA detection in cervical exfoliated cells as a triage for human papillomavirus-positive women. Journal of the National Cancer Institute. 106. PMID 25190727 DOI: 10.1093/jnci/dju241  0.01
2014 Cheng X. Structural and functional coordination of DNA and histone methylation. Cold Spring Harbor Perspectives in Biology. 6. PMID 25085914 DOI: 10.1101/cshperspect.a018747  0.12
2014 Cheng X, Dai D, Yuan Z, Peng L, He Y, Yeung ES. Color difference amplification between gold nanoparticles in colorimetric analysis with actively controlled multiband illumination. Analytical Chemistry. 86: 7584-92. PMID 25051181 DOI: 10.1021/ac501448w  0.01
2014 Rotili D, Tarantino D, Marrocco B, Gros C, Masson V, Poughon V, Ausseil F, Chang Y, Labella D, Cosconati S, Di Maro S, Novellino E, Schnekenburger M, Grandjenette C, Bouvy C, ... ... Cheng X, et al. Properly substituted analogues of BIX-01294 lose inhibition of G9a histone methyltransferase and gain selective anti-DNA methyltransferase 3A activity. Plos One. 9: e96941. PMID 24810902 DOI: 10.1371/journal.pone.0096941  0.01
2014 Hao J, Xiong B, Cheng X, He Y, Yeung ES. High-throughput sulfide sensing with colorimetric analysis of single Au-Ag core-shell nanoparticles. Analytical Chemistry. 86: 4663-7. PMID 24809220 DOI: 10.1021/ac500376e  0.01
2014 Cheng X, Dai D, Xu D, He Y, Yeung ES. Subdiffraction-limited plasmonic imaging with anisotropic metal nanoparticles. Analytical Chemistry. 86: 2303-7. PMID 24533508 DOI: 10.1021/ac403512w  0.01
2014 Chiappe LM, Zhao B, O'Connor JK, Chunling G, Wang X, Habib M, Marugan-Lobon J, Meng Q, Cheng X. A new specimen of the Early Cretaceous bird Hongshanornis longicresta: insights into the aerodynamics and diet of a basal ornithuromorph. Peerj. 2: e234. PMID 24482756 DOI: 10.7717/peerj.234  0.01
2014 Tao X, Mei F, Agrawal A, Peters CJ, Ksiazek TG, Cheng X, Tseng CT. Blocking of exchange proteins directly activated by cAMP leads to reduced replication of Middle East respiratory syndrome coronavirus. Journal of Virology. 88: 3902-10. PMID 24453361 DOI: 10.1128/JVI.03001-13  0.01
2014 Myrick LK, Nakamoto-Kinoshita M, Lindor NM, Kirmani S, Cheng X, Warren ST. Fragile X syndrome due to a missense mutation. European Journal of Human Genetics : Ejhg. 22: 1185-9. PMID 24448548 DOI: 10.1038/ejhg.2013.311  0.01
2014 Wang H, Cui XX, Goodin S, Ding N, Van Doren J, Du Z, Huang MT, Liu Y, Cheng X, Dipaola RS, Conney AH, Zheng X. Inhibition of IL-6 expression in LNCaP prostate cancer cells by a combination of atorvastatin and celecoxib. Oncology Reports. 31: 835-41. PMID 24296978 DOI: 10.3892/or.2013.2885  0.01
2014 Chen H, Wild C, Zhou X, Ye N, Cheng X, Zhou J. Recent advances in the discovery of small molecules targeting exchange proteins directly activated by cAMP (EPAC). Journal of Medicinal Chemistry. 57: 3651-65. PMID 24256330 DOI: 10.1021/jm401425e  0.01
2014 Almahariq M, Mei FC, Cheng X. Cyclic AMP sensor EPAC proteins and energy homeostasis. Trends in Endocrinology and Metabolism: Tem. 25: 60-71. PMID 24231725 DOI: 10.1016/j.tem.2013.10.004  0.01
2013 Gong B, Shelite T, Mei FC, Ha T, Hu Y, Xu G, Chang Q, Wakamiya M, Ksiazek TG, Boor PJ, Bouyer DH, Popov VL, Chen J, Walker DH, Cheng X. Exchange protein directly activated by cAMP plays a critical role in bacterial invasion during fatal rickettsioses. Proceedings of the National Academy of Sciences of the United States of America. 110: 19615-20. PMID 24218580 DOI: 10.1073/pnas.1314400110  0.01
2013 Sima N, Cheng X, Ye F, Ma D, Xie X, Lü W. The overexpression of scaffolding protein NEDD9 promotes migration and invasion in cervical cancer via tyrosine phosphorylated FAK and SRC. Plos One. 8: e74594. PMID 24058594 DOI: 10.1371/journal.pone.0074594  0.01
2013 Li S, Hu T, Chen Y, Zhou H, Li X, Cheng X, Yang R, Wang S, Xie X, Ma D. Adjuvant chemotherapy, a valuable alternative option in selected patients with cervical cancer. Plos One. 8: e73837. PMID 24058496 DOI: 10.1371/journal.pone.0073837  0.01
2013 Jin H, Sun Y, Wang S, Cheng X. Matrine activates PTEN to induce growth inhibition and apoptosis in V600EBRAF harboring melanoma cells. International Journal of Molecular Sciences. 14: 16040-57. PMID 23912239 DOI: 10.3390/ijms140816040  0.01
2013 Jiao J, Huang L, Ye F, Shi M, Cheng X, Wang X, Hu D, Xie X, Lu W. Cyclin D1 affects epithelial-mesenchymal transition in epithelial ovarian cancer stem cell-like cells. Oncotargets and Therapy. 6: 667-77. PMID 23836980 DOI: 10.2147/OTT.S44177  0.01
2013 Gong B, Lee YS, Lee I, Shelite TR, Kunkeaw N, Xu G, Lee K, Jeon SH, Johnson BH, Chang Q, Ha T, Mendell NL, Cheng X, Bouyer DH, Boor PJ, et al. Compartmentalized, functional role of angiogenin during spotted fever group rickettsia-induced endothelial barrier dysfunction: evidence of possible mediation by host tRNA-derived small noncoding RNAs. Bmc Infectious Diseases. 13: 285. PMID 23800282 DOI: 10.1186/1471-2334-13-285  0.01
2013 Chepurny OG, Bertinetti D, Diskar M, Leech CA, Afshari P, Tsalkova T, Cheng X, Schwede F, Genieser HG, Herberg FW, Holz GG. Stimulation of proglucagon gene expression by human GPR119 in enteroendocrine L-cell line GLUTag. Molecular Endocrinology (Baltimore, Md.). 27: 1267-82. PMID 23798572 DOI: 10.1210/me.2013-1029  0.01
2013 Nicholson TB, Singh AK, Su H, Hevi S, Wang J, Bajko J, Li M, Valdez R, Goetschkes M, Capodieci P, Loureiro J, Cheng X, Li E, Kinzel B, Labow M, et al. A hypomorphic lsd1 allele results in heart development defects in mice. Plos One. 8: e60913. PMID 23637775 DOI: 10.1371/journal.pone.0060913  0.01
2013 Peng Z, Ji Z, Mei F, Lu M, Ou Y, Cheng X. Lithium inhibits tumorigenic potential of PDA cells through targeting hedgehog-GLI signaling pathway. Plos One. 8: e61457. PMID 23626687 DOI: 10.1371/journal.pone.0061457  0.01
2013 Chen H, Ding C, Wild C, Liu H, Wang T, White MA, Cheng X, Zhou J. Efficient Synthesis of ESI-09, A Novel Non-cyclic Nucleotide EPAC Antagonist. Tetrahedron Letters. 54: 1546-1549. PMID 23459418 DOI: 10.1016/j.tetlet.2013.01.024  0.01
2013 Wang P, Cheng X, Fu Z, Zhou C, Lu W, Xie X. Reduced expression of NDUFS3 and its clinical significance in serous ovarian cancer. International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. 23: 622-9. PMID 23446378 DOI: 10.1097/IGC.0b013e318287a90d  0.01
2013 Ou Y, Lin L, Yang X, Pan Q, Cheng X. Antidiabetic potential of phycocyanin: effects on KKAy mice. Pharmaceutical Biology. 51: 539-44. PMID 23368938 DOI: 10.3109/13880209.2012.747545  0.01
2013 Chen H, Tsalkova T, Chepurny OG, Mei FC, Holz GG, Cheng X, Zhou J. Identification and characterization of small molecules as potent and specific EPAC2 antagonists. Journal of Medicinal Chemistry. 56: 952-62. PMID 23286832 DOI: 10.1021/jm3014162  0.01
2013 Jiang Y, Ou Y, Cheng X. Role of TSG101 in cancer. Frontiers in Bioscience (Landmark Edition). 18: 279-88. PMID 23276921  0.01
2013 Yan J, Mei FC, Cheng H, Lao DH, Hu Y, Wei J, Patrikeev I, Hao D, Stutz SJ, Dineley KT, Motamedi M, Hommel JD, Cunningham KA, Chen J, Cheng X. Enhanced leptin sensitivity, reduced adiposity, and improved glucose homeostasis in mice lacking exchange protein directly activated by cyclic AMP isoform 1. Molecular and Cellular Biology. 33: 918-26. PMID 23263987 DOI: 10.1128/MCB.01227-12  0.01
2013 Cheng X, Feng Y, Wang X, Wan X, Xie X, Lu W. The effectiveness of conization treatment for post-menopausal women with high-grade cervical intraepithelial neoplasia. Experimental and Therapeutic Medicine. 5: 185-188. PMID 23251264 DOI: 10.3892/etm.2012.748  0.01
2013 Almahariq M, Tsalkova T, Mei FC, Chen H, Zhou J, Sastry SK, Schwede F, Cheng X. A novel EPAC-specific inhibitor suppresses pancreatic cancer cell migration and invasion. Molecular Pharmacology. 83: 122-8. PMID 23066090 DOI: 10.1124/mol.112.080689  0.01
2012 White MA, Li S, Tsalkova T, Mei FC, Liu T, Woods VL, Cheng X. Structural analyses of a constitutively active mutant of exchange protein directly activated by cAMP. Plos One. 7: e49932. PMID 23189173 DOI: 10.1371/journal.pone.0049932  0.01
2012 Ou Y, Lin L, Pan Q, Yang X, Cheng X. Preventive effect of phycocyanin from Spirulina platensis on alloxan-injured mice. Environmental Toxicology and Pharmacology. 34: 721-6. PMID 23121873 DOI: 10.1016/j.etap.2012.09.016  0.01
2012 Tsalkova T, Mei FC, Li S, Chepurny OG, Leech CA, Liu T, Holz GG, Woods VL, Cheng X. Isoform-specific antagonists of exchange proteins directly activated by cAMP. Proceedings of the National Academy of Sciences of the United States of America. 109: 18613-8. PMID 23091014 DOI: 10.1073/pnas.1210209109  0.01
2012 Lu M, Huang Y, White MA, Wu X, Liu N, Cheng X, Chen Y. Dual catalysis mode for the dicarbonyl reduction catalyzed by diketoreductase. Chemical Communications (Cambridge, England). 48: 11352-4. PMID 23073461 DOI: 10.1039/c2cc36334h  0.01
2012 Cheng X, Quintás-Cardama A, Golemovic M, Zingaro R, Gao MZ, Freireich EJ, Andreeff M, Kantarjian HM, Verstovsek S. The organic arsenic derivative GMZ27 induces PML-RARα-independent apoptosis in myeloid leukemia cells. Anticancer Research. 32: 2871-80. PMID 22753750  0.01
2012 Chen H, Tsalkova T, Mei FC, Hu Y, Cheng X, Zhou J. 5-Cyano-6-oxo-1,6-dihydro-pyrimidines as potent antagonists targeting exchange proteins directly activated by cAMP. Bioorganic & Medicinal Chemistry Letters. 22: 4038-43. PMID 22607683 DOI: 10.1016/j.bmcl.2012.04.082  0.01
2012 Nicholson TB, Su H, Hevi S, Wang J, Bajko J, Li M, Valdez R, Loureiro J, Cheng X, Li E, Kinzel B, Labow M, Chen T. Retraction: Defective heart development in hypomorphic LSD1 mice. Cell Research. PMID 22491473 DOI: 10.1038/cr.2012.60  0.01
2012 Yuan Z, Cheng J, Cheng X, He Y, Yeung ES. Highly sensitive DNA hybridization detection with single nanoparticle flash-lamp darkfield microscopy. The Analyst. 137: 2930-2. PMID 22353800 DOI: 10.1039/c2an16171k  0.01
2012 Tejedor Garcia N, Garcia Bermejo L, Fernandez Martinez AB, Olmos Centenera G, Kumari R, Xu Q, Cheng X, Watson S, de Lucio Cazaña FJ. MEDLINE-based assessment of animal studies on Chinese herbal medicine. Journal of Ethnopharmacology. 140: 545-9. PMID 22353429 DOI: 10.1016/j.jep.2012.02.008  0.01
2012 Tsalkova T, Mei FC, Cheng X. A fluorescence-based high-throughput assay for the discovery of exchange protein directly activated by cyclic AMP (EPAC) antagonists. Plos One. 7: e30441. PMID 22276201 DOI: 10.1371/journal.pone.0030441  0.01
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