Jose A. Lasalde-Dominicci - Publications

Affiliations: 
University of Puerto Rico, Rio Piedras (Puerto Rico) 
Area:
Medical Biophysics, Biochemistry

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Delgado-Vélez M, Quesada O, Villalobos-Santos JC, Maldonado-Hernández R, Asmar-Rovira G, Stevens RC, Lasalde-Dominicci JA. Pursuing High-Resolution Structures of Nicotinic Acetylcholine Receptors: Lessons Learned from Five Decades. Molecules (Basel, Switzerland). 26. PMID 34641297 DOI: 10.3390/molecules26195753  0.804
2020 Maldonado-Hernández R, Quesada O, Lasalde-Dominicci JA. Biophysical characterization dataset of native nicotinic acetylcholine receptor in lipid-like detergent complexes. Data in Brief. 32: 106230. PMID 32939382 DOI: 10.1016/J.Dib.2020.106230  0.401
2020 Maldonado-Hernández R, Quesada O, Colón-Sáez JO, Lasalde-Dominicci JA. Sequential purification and characterization of Torpedo californica nAChR-DC supplemented with CHS for high-resolution crystallization studies. Analytical Biochemistry. 113887. PMID 32763308 DOI: 10.1016/J.Ab.2020.113887  0.398
2018 Garton DR, Ross SG, Maldonado-Hernández R, Quick M, Lasalde-Dominicci JA, Lizardi-Ortiz JE. Amphetamine enantiomers inhibit homomeric α7 nicotinic receptor through a competitive mechanism and within the intoxication levels in humans. Neuropharmacology. 144: 172-183. PMID 30359640 DOI: 10.1016/J.Neuropharm.2018.10.032  0.418
2018 Capó-Vélez CM, Delgado-Vélez M, Báez-Pagán CA, Lasalde-Dominicci JA. Nicotinic Acetylcholine Receptors in HIV: Possible Roles During HAND and Inflammation. Cellular and Molecular Neurobiology. PMID 30008143 DOI: 10.1007/S10571-018-0603-8  0.767
2018 Delgado-Vélez M, Lasalde-Dominicci JA. The Cholinergic Anti-Inflammatory Response and the Role of Macrophages in HIV-Induced Inflammation. International Journal of Molecular Sciences. 19. PMID 29772664 DOI: 10.3390/Ijms19051473  0.36
2018 Capó-Vélez CM, Morales-Vargas B, García-González A, Grajales-Reyes JG, Delgado-Vélez M, Madera B, Báez-Pagán CA, Quesada O, Lasalde-Dominicci JA. The alpha7-nicotinic receptor contributes to gp120-induced neurotoxicity: implications in HIV-associated neurocognitive disorders. Scientific Reports. 8: 1829. PMID 29379089 DOI: 10.1038/S41598-018-20271-X  0.784
2017 Grajales-Reyes JG, García-González A, María-Ríos JC, Grajales-Reyes GE, Delgado-Vélez M, Báez-Pagán CA, Quesada O, Gómez CM, Lasalde-Dominicci JA. A Panel of Slow-Channel Congenital Myasthenic Syndrome Mice Reveals a Unique Locomotor Behavioral Signature. Journal of Neuromuscular Diseases. PMID 29036836 DOI: 10.3233/Jnd-170226  0.796
2017 Quesada O, Colon-Sáez JO, González CL, González CL, Maldonado R, Rosado I, Espinal A, Acevedo J, Lasalde-Dominicci JA. Lipid Profile and Functionality of Nicotinic Aceytilcholine Receptor from Torpedo Californica Solubillized with Cyclofos Detergent Family Biophysical Journal. 112: 227a. DOI: 10.1016/J.Bpj.2016.11.1250  0.436
2016 Quesada O, González-Freire C, Ferrer MC, Colón-Sáez JO, Fernández-García E, Mercado J, Dávila A, Morales R, Lasalde-Dominicci JA. Uncovering the lipidic basis for the preparation of functional nicotinic acetylcholine receptor detergent complexes for structural studies. Scientific Reports. 6: 32766. PMID 27641515 DOI: 10.1038/Srep32766  0.445
2016 Báez-Pagán CA, Del Hoyo-Rivera N, Quesada O, Otero-Cruz JD, Lasalde-Dominicci JA. Heterogeneous Inhibition in Macroscopic Current Responses of Four Nicotinic Acetylcholine Receptor Subtypes by Cholesterol Enrichment. The Journal of Membrane Biology. PMID 27116687 DOI: 10.1007/S00232-016-9896-Z  0.81
2016 Padilla-Morales LF, Colón-Sáez JO, González-Nieves JE, Quesada-González O, Lasalde-Dominicci JA. Functionality and stability data of detergent purified nAChR from Torpedo using lipidic matrixes and macroscopic electrophysiology. Data in Brief. 6: 433-7. PMID 26870753 DOI: 10.1016/J.Dib.2015.12.010  0.461
2016 Valdés Fernández BN, Lasalde-Dominicci JA. Assessment of Nicotinic Acetylcholine Receptor Detergent Complexes Purity and Stability for Structural Studies Biophysical Journal. 110: 388a. DOI: 10.1016/J.Bpj.2015.11.2097  0.452
2015 Delgado-Vélez M, Báez-Pagán CA, Gerena Y, Quesada O, Santiago-Pérez LI, Capó-Vélez CM, Wojna V, Meléndez L, León-Rivera R, Silva W, Lasalde-Dominicci JA. The α7-nicotinic receptor is upregulated in immune cells from HIV-seropositive women: consequences to the cholinergic anti-inflammatory response. Clinical & Translational Immunology. 4: e53. PMID 26719799 DOI: 10.1038/Cti.2015.31  0.748
2015 Ramos FM, Delgado-Vélez M, Ortiz ÁL, Báez-Pagán CA, Quesada O, Lasalde-Dominicci JA. Expression of CHRFAM7A and CHRNA7 in neuronal cells and postmortem brain of HIV-infected patients: considerations for HIV-associated neurocognitive disorder. Journal of Neurovirology. PMID 26567012 DOI: 10.1007/S13365-015-0401-8  0.759
2015 Padilla-Morales LF, Colón-Sáez JO, González-Nieves JE, Quesada-González O, Lasalde-Dominicci JA. Assessment of the functionality and stability of detergent purified nAChR from Torpedo using lipidic matrixes and macroscopic electrophysiology. Biochimica Et Biophysica Acta. 1858: 47-56. PMID 26454038 DOI: 10.1016/J.Bbamem.2015.10.002  0.49
2015 Oyola-Cintrón J, Caballero-Rivera D, Ballester L, Baéz-Pagán CA, Martínez HL, Vélez-Arroyo KP, Quesada O, Lasalde-Dominicci JA. Lateral Diffusion, Function, and Expression of the Slow Channel Congenital Myasthenia Syndrome αC418W Nicotinic Receptor Mutation with Changes in Lipid Raft Components. The Journal of Biological Chemistry. 290: 26790-800. PMID 26354438 DOI: 10.1074/Jbc.M115.678573  0.821
2015 Biaggi-Labiosa NM, Avilés-Pagán E, Caballero-Rivera D, Báez-Pagán CA, Lasalde-Dominicci JA. Engineering α4β2 nAChRs with reduced or increased nicotine sensitivity via selective disruption of consensus sites in the M3-M4 cytoplasmic loop of the α4 subunit. Neuropharmacology. 99: 273-284. PMID 25957813 DOI: 10.1016/J.Neuropharm.2015.04.022  0.789
2015 Báez-Pagán CA, Delgado-Vélez M, Lasalde-Dominicci JA. Activation of the Macrophage α7 Nicotinic Acetylcholine Receptor and Control of Inflammation. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 25870122 DOI: 10.1007/S11481-015-9601-5  0.771
2015 Zhu H, Grajales-Reyes GE, Alicea-Vázquez V, Grajales-Reyes JG, Robinson K, Pytel P, Báez-Pagán CA, Lasalde-Dominicci JA, Gomez CM. Fluoxetine is neuroprotective in slow-channel congenital myasthenic syndrome. Experimental Neurology. 270: 88-94. PMID 25448156 DOI: 10.1016/J.Expneurol.2014.10.008  0.775
2014 Padilla-Morales LF, González Nieves JE, Lanauze C, Báez-Págan CA, Quesada-González O, Lasalde-Dominicci JA. Progresive Analysis of nAChR Stability in the Lipidic Cubic Phase: nAChR Detergent Solubilization and Fractional Mobility Biophysical Journal. 106: 340a. DOI: 10.1016/J.Bpj.2013.11.1945  0.479
2013 Grajales-Reyes GE, Báez-Pagán CA, Zhu H, Grajales-Reyes JG, Delgado-Vélez M, García-Beltrán WF, Luciano CA, Quesada O, Ramírez R, Gómez CM, Lasalde-Dominicci JA. Transgenic mouse model reveals an unsuspected role of the acetylcholine receptor in statin-induced neuromuscular adverse drug reactions. The Pharmacogenomics Journal. 13: 362-8. PMID 22688219 DOI: 10.1038/Tpj.2012.21  0.365
2012 Caballero-Rivera D, Cruz-Nieves OA, Oyola-Cintrón J, Torres-Nunez DA, Otero-Cruz JD, Lasalde-Dominicci JA. Tryptophan scanning mutagenesis reveals distortions in the helical structure of the δM4 transmembrane domain of the Torpedo californica nicotinic acetylcholine receptor. Channels (Austin, Tex.). 6: 111-23. PMID 22622285 DOI: 10.4161/Chan.19540  0.831
2012 Salgado IK, Serrano M, García JO, Martínez NA, Maldonado HM, Báez-Pagán CA, Lasalde-Dominicci JA, Silva WI. SorLA in glia: shared subcellular distribution patterns with caveolin-1. Cellular and Molecular Neurobiology. 32: 409-21. PMID 22127416 DOI: 10.1007/S10571-011-9771-5  0.748
2012 Ballester LY, Capó-Vélez CM, García-Beltrán WF, Ramos FM, Vázquez-Rosa E, Ríos R, Mercado JR, Meléndez RI, Lasalde-Dominicci JA. Up-regulation of the neuronal nicotinic receptor α7 by HIV glycoprotein 120: potential implications for HIV-associated neurocognitive disorder. The Journal of Biological Chemistry. 287: 3079-86. PMID 22084248 DOI: 10.1074/Jbc.M111.262543  0.381
2011 Padilla-Morales LF, Morales-Pérez CL, De La Cruz-Rivera PC, Asmar-Rovira G, Báez-Pagán CA, Quesada O, Lasalde-Dominicci JA. Effects of lipid-analog detergent solubilization on the functionality and lipidic cubic phase mobility of the Torpedo californica nicotinic acetylcholine receptor. The Journal of Membrane Biology. 243: 47-58. PMID 21922299 DOI: 10.1007/S00232-011-9392-4  0.811
2011 Caballero-Rivera D, Cruz-Nieves OA, Oyola-Cintrón J, Torres-Núñez DA, Otero-Cruz JD, Lasalde-Dominicci JA. Fourier transform coupled tryptophan scanning mutagenesis identifies a bending point on the lipid-exposed δM3 transmembrane domain of the Torpedo californica nicotinic acetylcholine receptor. Channels (Austin, Tex.). 5: 345-56. PMID 21785268 DOI: 10.4161/Chan.5.4.17082  0.827
2011 del Hoyo-Rivera N, Báez-Pagán CA, Quesada O, Lasalde-Dominicci JA. Modulation of the Nicotinic Acetylcholine Receptor Function by Cholesterol Biophysical Journal. 100: 276a. DOI: 10.1016/J.Bpj.2010.12.1717  0.812
2011 Padilla-Morales LF, Morales-Pérez CL, De La Cruz-Rivera PC, Lopez-Cruz LM, Asmar-Rovira GA, Stevens RC, Quesada O, Lasalde-Dominicci JA. Characterization of Nicotinic Acetylcholine Receptor from Torpedo Californica Uding Lipid Analog Detergents Biophysical Journal. 100: 276a. DOI: 10.1016/J.Bpj.2010.12.1715  0.818
2010 Otero-Cruz JD, Báez-Pagán CA, Dorna-Pérez L, Grajales-Reyes GE, Ramírez-Ordoñez RT, Luciano CA, Gómez CM, Lasalde-Dominicci JA. Decoding pathogenesis of slow-channel congenital myasthenic syndromes using recombinant expression and mice models. Puerto Rico Health Sciences Journal. 29: 4-17. PMID 20222328  0.773
2010 Padilla-Morales LF, Morales-Perez CL, De La Cruz-Rivera P, Lopez-Cruz LM, Asmar-Rovira G, Stevens R, Quesada O, Lasalde-Dominicci JA. Efficient Isolation and Characterization of Nicotinic Acetylcholine Receptor from Torpedo Californica using Lipid Analog Detergents Biophysical Journal. 98: 132a-133a. DOI: 10.1016/J.Bpj.2009.12.716  0.831
2010 Caballero-Rivera D, Cruz-Nieves OA, Oyola-Cintrón J, Otero-Cruz JD, Torres-Núñez DA, Rodríguez-Espada D, Hoyo-Rivera ND, Lasalde-Dominicci JA. Fourier Transform Coupled Tryptophan Scanning Mutagenesis of the Lipid Exposed DM3 And DM4 Transmembrane Domains of the Torpedo Californica Acetylcholine Receptor Biophysical Journal. 98: 132a. DOI: 10.1016/J.Bpj.2009.12.712  0.818
2010 Oyola-Cintrón J, Caballero-Rivera D, Ballester L, Martínez L, Nogueras CJ, Ríos-Morales RY, Quesada O, Lasalde-Dominicci JA. Potential Implications of Cholesterol and Phosphatidylinositol 4,5-Bisphosphate (PIP2) Interactions With The Cholesterol-Sensitive AC418W Acetylcholine Receptor Mutation at Lipid Rafts Biophysical Journal. 98: 131a. DOI: 10.1016/J.Bpj.2009.12.710  0.447
2010 Biaggi-Labiosa NM, Lasalde-Dominicci JA. Contribution of Phosphorylation Residues in the A4 Subunit to the α4β2 Neuronal Nachr Function and Expression Biophysical Journal. 98: 130a. DOI: 10.1016/J.Bpj.2009.12.703  0.807
2009 López-Hernández GY, Biaggi-Labiosa NM, Torres-Cintrón A, Ortiz-Acevedo A, Lasalde-Dominicci JA. Contribution of position alpha4S336 on functional expression and up-regulation of alpha4beta2 neuronal nicotinic receptors. Cellular and Molecular Neurobiology. 29: 41-53. PMID 18818999 DOI: 10.1007/S10571-008-9293-Y  0.802
2009 Oyola-Cintrón J, Caballero-Rivera D, Ballester L, Vélez-Arroyo K, García-Matos J, Martínez L, Nogueras CJ, Quesada O, García J, Silva WI, Lasalde-Dominicci JA. Role of Membrane Cholesterol Levels in the Lateral Diffusion and Function of the Novel Slow Channel Congenital Myasthenia Syndrome αC418W AChR Mutant Biophysical Journal. 96: 168a. DOI: 10.1016/J.Bpj.2008.12.777  0.467
2008 Díaz-De León R, Otero-Cruz JD, Torres-Nuñez DA, Casiano A, Lasalde-Dominicci JA. Tryptophan scanning of the acetylcholine receptor's betaM4 transmembrane domain: decoding allosteric linkage at the lipid-protein interface with ion-channel gating. Channels (Austin, Tex.). 2: 439-48. PMID 19066450 DOI: 10.4161/Chan.2.6.7130  0.832
2008 Lizardi-Ortiz JE, Hyzinski-García MC, Fernández-Gerena JL, Osorio-Martínez KM, Velázquez-Rivera E, Valle-Avilés FL, Lasalde-Dominicci JA. Aromaticity at the water-hydrocarbon core interface of the membrane: consequences on the nicotinic acetylcholine receptor. Channels (Austin, Tex.). 2: 191-201. PMID 18836298 DOI: 10.4161/Chan.2.3.6385  0.485
2008 Báez-Pagán CA, Martínez-Ortiz Y, Otero-Cruz JD, Salgado-Villanueva IK, Velázquez G, Ortiz-Acevedo A, Quesada O, Silva WI, Lasalde-Dominicci JA. Potential role of caveolin-1-positive domains in the regulation of the acetylcholine receptor's activatable pool: implications in the pathogenesis of a novel congenital myasthenic syndrome. Channels (Austin, Tex.). 2: 180-90. PMID 18836288 DOI: 10.4161/Chan.2.3.6155  0.819
2008 Nieves-Cintrón M, Caballero-Rivera D, Silva WI, Navedo MF, Lasalde-Dominicci JA. Functional contribution of alpha3L8' to the neuronal nicotinic alpha3 receptor. Journal of Neuroscience Research. 86: 2884-94. PMID 18615639 DOI: 10.1002/Jnr.21749  0.517
2008 Asmar-Rovira GA, Asseo-García AM, Quesada O, Hanson MA, Cheng A, Nogueras C, Lasalde-Dominicci JA, Stevens RC. Biophysical and ion channel functional characterization of the Torpedo californica nicotinic acetylcholine receptor in varying detergent-lipid environments. The Journal of Membrane Biology. 223: 13-26. PMID 18581036 DOI: 10.1007/S00232-008-9107-7  0.818
2008 Otero-Cruz JD, Torres-Núñez DA, Báez-Pagán CA, Lasalde-Dominicci JA. Fourier transform coupled to tryptophan-scanning mutagenesis: lessons from its application to the prediction of secondary structure in the acetylcholine receptor lipid-exposed transmembrane domains. Biochimica Et Biophysica Acta. 1784: 1200-7. PMID 18346473 DOI: 10.1016/J.Bbapap.2008.01.020  0.777
2007 Ochoa EL, Lasalde-Dominicci J. Cognitive deficits in schizophrenia: focus on neuronal nicotinic acetylcholine receptors and smoking. Cellular and Molecular Neurobiology. 27: 609-39. PMID 17554626 DOI: 10.1007/S10571-007-9149-X  0.38
2007 Otero-Cruz JD, Báez-Pagán CA, Caraballo-González IM, Lasalde-Dominicci JA. Tryptophan-scanning mutagenesis in the alphaM3 transmembrane domain of the muscle-type acetylcholine receptor. A spring model revealed. The Journal of Biological Chemistry. 282: 9162-71. PMID 17242410 DOI: 10.1074/Jbc.M607492200  0.804
2006 Guzmán GR, Ortiz-Acevedo A, Ricardo A, Rojas LV, Lasalde-Dominicci JA. The polarity of lipid-exposed residues contributes to the functional differences between Torpedo and muscle-type nicotinic receptors. The Journal of Membrane Biology. 214: 131-8. PMID 17530159 DOI: 10.1007/S00232-006-0051-0  0.502
2006 Nieves-Cintrón M, Caballero-Rivera D, Navedo MF, Lasalde-Dominicci JA. Contribution of valine 7' of TMD2 to gating of neuronal alpha3 receptor subtypes. Journal of Neuroscience Research. 84: 1778-88. PMID 17044037 DOI: 10.1002/Jnr.21085  0.489
2006 Zayas R, Lasalde-Dominicci J, Gomez CM. Macroscopic properties of spontaneous mutations in slow-channel syndrome: correlation by domain and disease severity. Synapse (New York, N.Y.). 60: 441-9. PMID 16881075 DOI: 10.1002/Syn.20317  0.416
2006 Navedo MF, Lasalde-Dominicci JA, Báez-Pagán CA, Díaz-Pérez L, Rojas LV, Maselli RA, Staub J, Schott K, Zayas R, Gomez CM. Novel beta subunit mutation causes a slow-channel syndrome by enhancing activation and decreasing the rate of agonist dissociation. Molecular and Cellular Neurosciences. 32: 82-90. PMID 16624571 DOI: 10.1016/J.Mcn.2006.02.004  0.784
2004 Santiago J, Guzmán GR, Torruellas K, Rojas LV, Lasalde-Dominicci JA. Tryptophan scanning mutagenesis in the TM3 domain of the Torpedo californica acetylcholine receptor beta subunit reveals an alpha-helical structure. Biochemistry. 43: 10064-70. PMID 15287734 DOI: 10.1021/Bi0362368  0.453
2004 López-Hernández GY, Sánchez-Padilla J, Ortiz-Acevedo A, Lizardi-Ortiz J, Salas-Vincenty J, Rojas LV, Lasalde-Dominicci JA. Nicotine-induced up-regulation and desensitization of alpha4beta2 neuronal nicotinic receptors depend on subunit ratio. The Journal of Biological Chemistry. 279: 38007-15. PMID 15247303 DOI: 10.1074/Jbc.M403537200  0.319
2004 Ortiz-Acevedo A, Melendez M, Asseo AM, Biaggi N, Rojas LV, Lasalde-Dominicci JA. Tryptophan scanning mutagenesis of the gammaM4 transmembrane domain of the acetylcholine receptor from Torpedo californica. The Journal of Biological Chemistry. 279: 42250-7. PMID 15247226 DOI: 10.1074/Jbc.M405132200  0.486
2004 Navedo M, Nieves M, Rojas L, Lasalde-Dominicci JA. Tryptophan substitutions reveal the role of nicotinic acetylcholine receptor alpha-TM3 domain in channel gating: differences between Torpedo and muscle-type AChR. Biochemistry. 43: 78-84. PMID 14705933 DOI: 10.1021/Bi0356496  0.471
2003 Guzmán GR, Santiago J, Ricardo A, Martí-Arbona R, Rojas LV, Lasalde-Dominicci JA. Tryptophan scanning mutagenesis in the alphaM3 transmembrane domain of the Torpedo californica acetylcholine receptor: functional and structural implications. Biochemistry. 42: 12243-50. PMID 14567686 DOI: 10.1021/Bi034764D  0.568
2002 Gomez CM, Maselli RA, Vohra BP, Navedo M, Stiles JR, Charnet P, Schott K, Rojas L, Keesey J, Verity A, Wollmann RW, Lasalde-Dominicci J. Novel delta subunit mutation in slow-channel syndrome causes severe weakness by novel mechanisms. Annals of Neurology. 51: 102-12. PMID 11782989 DOI: 10.1002/Ana.10077  0.423
2001 Santiago J, Guzmàn GR, Rojas LV, Marti R, Asmar-Rovira GA, Santana LF, McNamee M, Lasalde-Dominicci JA. Probing the effects of membrane cholesterol in the Torpedo californica acetylcholine receptor and the novel lipid-exposed mutation alpha C418W in Xenopus oocytes. The Journal of Biological Chemistry. 276: 46523-32. PMID 11567020 DOI: 10.1074/Jbc.M104563200  0.818
2001 Cruz-Martín A, Mercado JL, Rojas LV, McNamee MG, Lasalde-Dominicci JA. Tryptophan substitutions at lipid-exposed positions of the gamma M3 transmembrane domain increase the macroscopic ionic current response of the Torpedo californica nicotinic acetylcholine receptor. The Journal of Membrane Biology. 183: 61-70. PMID 11547353 DOI: 10.1007/S00232-001-0051-Z  0.471
2000 Tamamizu S, Guzmán GR, Santiago J, Rojas LV, McNamee MG, Lasalde-Dominicci JA. Functional effects of periodic tryptophan substitutions in the alpha M4 transmembrane domain of the Torpedo californica nicotinic acetylcholine receptor. Biochemistry. 39: 4666-73. PMID 10769122 DOI: 10.1021/Bi992835W  0.518
1999 Tamamizu S, Lee Y, Hung B, McNamee MG, Lasalde-Dominicci JA. Alteration in ion channel function of mouse nicotinic acetylcholine receptor by mutations in the M4 transmembrane domain. The Journal of Membrane Biology. 170: 157-64. PMID 10430659 DOI: 10.1007/S002329900545  0.47
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