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Alan D. Attie - Publications

University of Wisconsin, Madison, Madison, WI 

133 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Linke V, Overmyer KA, Miller IJ, Brademan DR, Hutchins PD, Trujillo EA, Reddy TR, Russell JD, Cushing EM, Schueler KL, Stapleton DS, Rabaglia ME, Keller MP, Gatti DM, Keele GR, ... ... Attie AD, et al. A large-scale genome-lipid association map guides lipid identification. Nature Metabolism. PMID 32958938 DOI: 10.1038/s42255-020-00278-3  0.56
2020 Xie H, Yang K, Winston-McPherson GN, Stapleton DS, Keller MP, Attie AD, Smith KA, Tang W. From methylene bridged diindole to carbonyl linked benzimidazoleindole: Development of potent and metabolically stable PCSK9 modulators. European Journal of Medicinal Chemistry. 206: 112678. PMID 32823006 DOI: 10.1016/j.ejmech.2020.112678  0.56
2020 Oh JH, Schueler KL, Stapleton DS, Alexander LM, Yen CE, Keller MP, Attie AD, van Pijkeren JP. Secretion of Recombinant Interleukin-22 by Engineered Lactobacillus reuteri Reduces Fatty Liver Disease in a Mouse Model of Diet-Induced Obesity. Msphere. 5. PMID 32581074 DOI: 10.1128/mSphere.00183-20  0.56
2019 Kemis JH, Linke V, Barrett KL, Boehm FJ, Traeger LL, Keller MP, Rabaglia ME, Schueler KL, Stapleton DS, Gatti DM, Churchill GA, Amador-Noguez D, Russell JD, Yandell BS, Broman KW, ... ... Attie AD, et al. Genetic determinants of gut microbiota composition and bile acid profiles in mice. Plos Genetics. 15: e1008073. PMID 31465442 DOI: 10.1371/journal.pgen.1008073  0.56
2019 Keller MP, Rabaglia ME, Schueler KL, Stapleton DS, Gatti DM, Vincent M, Mitok KA, Wang Z, Ishimura T, Simonett SP, Emfinger CH, Das R, Beck T, Kendziorski C, Broman KW, ... ... Attie AD, et al. Gene loci associated with insulin secretion in islets from non-diabetic mice. The Journal of Clinical Investigation. 130. PMID 31343992 DOI: 10.1172/JCI129143  0.56
2019 Niemi NM, Wilson GM, Overmyer KA, Vögtle FN, Myketin L, Lohman DC, Schueler KL, Attie AD, Meisinger C, Coon JJ, Pagliarini DJ. Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis. Nature Communications. 10: 3197. PMID 31324765 DOI: 10.1038/s41467-019-11047-6  0.56
2019 Alexander LM, Oh JH, Stapleton DS, Schueler KL, Keller MP, Attie AD, van Pijkeren JP. Exploiting Prophage-mediated Lysis for Biotherapeutic Release by . Applied and Environmental Microbiology. PMID 30683744 DOI: 10.1128/AEM.02335-18  0.56
2018 Oh JH, Alexander LM, Pan M, Schueler KL, Keller MP, Attie AD, Walter J, van Pijkeren JP. Dietary Fructose and Microbiota-Derived Short-Chain Fatty Acids Promote Bacteriophage Production in the Gut Symbiont Lactobacillus reuteri. Cell Host & Microbe. PMID 30658906 DOI: 10.1016/j.chom.2018.11.016  0.56
2018 Keller MP, Gatti DM, Schueler KL, Rabaglia ME, Stapleton DS, Simecek P, Vincent M, Allen S, Broman AT, Bacher R, Kendziorski C, Broman KW, Yandell BS, Churchill GA, Attie AD. Genetic Drivers of Pancreatic Islet Function. Genetics. PMID 29567659 DOI: 10.1534/genetics.118.300864  0.56
2018 Mitok KA, Freiberger EC, Schueler KL, Rabaglia ME, Stapleton DS, Kwiecien NW, Malec PA, Hebert AS, Broman AT, Kennedy RT, Keller MP, Coon JJ, Attie AD. Islet proteomics reveals genetic variation in dopamine production resulting in altered insulin secretion. The Journal of Biological Chemistry. PMID 29496998 DOI: 10.1074/jbc.RA117.001102  0.56
2018 Ye R, Gordillo R, Shao M, Onodera T, Chen Z, Chen S, Lin X, SoRelle JA, Li X, Tang M, Keller MP, Kuliawat R, Attie AD, Gupta RK, Holland WL, et al. Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity. The Journal of Clinical Investigation. PMID 29457786 DOI: 10.1172/JCI97702  0.44
2018 Lin J, Zheng S, Attie AD, Keller MP, Bernlohr DA, Blaner WS, Newberry EP, Davidson NO, Chen A. Perilipin 5 and Liver fatty acid binding protein function to restore quiescence in mouse hepatic stellate cells. Journal of Lipid Research. PMID 29317465 DOI: 10.1194/jlr.M077487  0.44
2017 Yu Q, Canales A, Glover MS, Das R, Shi X, Liu Y, Keller MP, Attie AD, Li L. Targeted Mass Spectrometry Approach Enabled Discovery of O-Glycosylated Insulin and Related Signaling Peptides in Mouse and Human Pancreatic Islets. Analytical Chemistry. 89: 9184-9191. PMID 28726377 DOI: 10.1021/acs.analchem.7b01926  0.44
2017 Ye S, Bacher R, Keller MP, Attie AD, Kendziorski C. Statistical Methods for Latent Class Quantitative Trait Loci Mapping. Genetics. 206: 1309-1317. PMID 28550015 DOI: 10.1534/genetics.117.203885  0.44
2017 Kreznar JH, Keller MP, Traeger LL, Rabaglia ME, Schueler KL, Stapleton DS, Zhao W, Vivas EI, Yandell BS, Broman AT, Hagenbuch B, Attie AD, Rey FE. Host Genotype and Gut Microbiome Modulate Insulin Secretion and Diet-Induced Metabolic Phenotypes. Cell Reports. 18: 1739-1750. PMID 28199845 DOI: 10.1016/j.celrep.2017.01.062  0.56
2016 Keller MP, Paul PK, Rabaglia ME, Stapleton DS, Schueler KL, Broman AT, Ye SI, Leng N, Brandon CJ, Neto EC, Plaisier CL, Simonett SP, Kebede MA, Sheynkman GM, Klein MA, ... ... Attie AD, et al. The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets. Plos Genetics. 12: e1006466. PMID 27935966 DOI: 10.1371/journal.pgen.1006466  0.68
2016 Krautkramer KA, Kreznar JH, Romano KA, Vivas EI, Barrett-Wilt GA, Rabaglia ME, Keller MP, Attie AD, Rey FE, Denu JM. Diet-Microbiota Interactions Mediate Global Epigenetic Programming in Multiple Host Tissues. Molecular Cell. 64: 982-992. PMID 27889451 DOI: 10.1016/j.molcel.2016.10.025  0.56
2016 Paul PK, Rabaglia ME, Wang CY, Stapleton DS, Leng N, Kendziorski C, Lewis PW, Keller MP, Attie AD. Histone chaperone ASF1B promotes human β-cell proliferation via recruitment of histone H3.3. Cell Cycle (Georgetown, Tex.). 15: 3191-3202. PMID 27753532 DOI: 10.1080/15384101.2016.1241914  0.56
2016 Chennamsetty I, Coronado M, Contrepois K, Keller MP, Carcamo-Orive I, Sandin J, Fajardo G, Whittle AJ, Fathzadeh M, Snyder M, Reaven G, Attie AD, Bernstein D, Quertermous T, Knowles JW. Nat1 Deficiency Is Associated with Mitochondrial Dysfunction and Exercise Intolerance in Mice. Cell Reports. 17: 527-540. PMID 27705799 DOI: 10.1016/j.celrep.2016.09.005  0.44
2016 Baughman JM, Rose CM, Kolumam G, Webster JD, Wilkerson EM, Merrill AE, Rhoads TW, Noubade R, Katavolos P, Lesch J, Stapleton DS, Rabaglia ME, Schueler KL, Asuncion R, Domeyer M, ... ... Attie AD, et al. NeuCode Proteomics Reveals Bap1 Regulation of Metabolism. Cell Reports. 16: 583-595. PMID 27373151 DOI: 10.1016/j.celrep.2016.05.096  0.56
2016 Tian J, Keller MP, Broman AT, Kendziorski C, Yandell BS, Attie AD, Broman KW. The Dissection of Expression Quantitative Trait Locus Hotspots. Genetics. 202: 1563-74. PMID 26837753 DOI: 10.1534/genetics.115.183624  0.56
2016 Gu T, Gatti DM, Srivastava A, Snyder EM, Raghupathy N, Simecek P, Svenson KL, Dotu I, Chuang JH, Keller MP, Attie AD, Braun RE, Churchill GA. Genetic Architectures of Quantitative Variation in RNA Editing Pathways. Genetics. 202: 787-98. PMID 26614740 DOI: 10.1534/genetics.115.179481  0.44
2015 Shortreed MR, Wenger CD, Frey BL, Sheynkman GM, Scalf M, Keller MP, Attie AD, Smith LM. Global Identification of Protein Post-translational Modifications in a Single-Pass Database Search. Journal of Proteome Research. 14: 4714-20. PMID 26418581 DOI: 10.1021/acs.jproteome.5b00599  0.44
2015 Tian J, Keller MP, Oler AT, Rabaglia ME, Schueler KL, Stapleton DS, Broman AT, Zhao W, Kendziorski C, Yandell BS, Hagenbuch B, Broman KW, Attie AD. Identification of the Bile Acid Transporter Slco1a6 as a Candidate Gene That Broadly Affects Gene Expression in Mouse Pancreatic Islets. Genetics. 201: 1253-62. PMID 26385979 DOI: 10.1534/genetics.115.179432  0.56
2015 Broman KW, Keller MP, Broman AT, Kendziorski C, Yandell BS, Sen Ś, Attie AD. Identification and Correction of Sample Mix-Ups in Expression Genetic Data: A Case Study. G3 (Bethesda, Md.). 5: 2177-86. PMID 26290572 DOI: 10.1534/g3.115.019778  0.56
2015 Shang J, Li J, Keller MP, Hohmeier HE, Wang Y, Feng Y, Zhou HH, Shen X, Rabaglia M, Soni M, Attie AD, Newgard CB, Thornberry NA, Howard AD, Zhou YP. Induction of miR-132 and miR-212 Expression by Glucagon-Like Peptide 1 (GLP-1) in Rodent and Human Pancreatic β-Cells. Molecular Endocrinology (Baltimore, Md.). 29: 1243-53. PMID 26218441 DOI: 10.1210/me.2014-1335  0.44
2014 Lai L, Leone TC, Keller MP, Martin OJ, Broman AT, Nigro J, Kapoor K, Koves TR, Stevens R, Ilkayeva OR, Vega RB, Attie AD, Muoio DM, Kelly DP. Energy metabolic reprogramming in the hypertrophied and early stage failing heart: a multisystems approach. Circulation. Heart Failure. 7: 1022-31. PMID 25236884 DOI: 10.1161/CIRCHEARTFAILURE.114.001469  0.44
2014 Munger SC, Raghupathy N, Choi K, Simons AK, Gatti DM, Hinerfeld DA, Svenson KL, Keller MP, Attie AD, Hibbs MA, Graber JH, Chesler EJ, Churchill GA. RNA-Seq alignment to individualized genomes improves transcript abundance estimates in multiparent populations. Genetics. 198: 59-73. PMID 25236449 DOI: 10.1534/genetics.114.165886  0.44
2014 Johnson LM, Barrick S, Hager MV, McFedries A, Homan EA, Rabaglia ME, Keller MP, Attie AD, Saghatelian A, Bisello A, Gellman SH. A potent α/β-peptide analogue of GLP-1 with prolonged action in vivo. Journal of the American Chemical Society. 136: 12848-51. PMID 25191938 DOI: 10.1021/ja507168t  0.56
2014 Kebede MA, Oler AT, Gregg T, Balloon AJ, Johnson A, Mitok K, Rabaglia M, Schueler K, Stapleton D, Thorstenson C, Wrighton L, Floyd BJ, Richards O, Raines S, Eliceiri K, ... ... Attie AD, et al. SORCS1 is necessary for normal insulin secretory granule biogenesis in metabolically stressed β cells. The Journal of Clinical Investigation. 124: 4240-56. PMID 25157818 DOI: 10.1172/JCI74072  0.68
2014 Kebede MA, Attie AD. Insights into obesity and diabetes at the intersection of mouse and human genetics. Trends in Endocrinology and Metabolism: Tem. 25: 493-501. PMID 25034129 DOI: 10.1016/j.tem.2014.06.006  0.68
2014 Bhatnagar S, Soni MS, Wrighton LS, Hebert AS, Zhou AS, Paul PK, Gregg T, Rabaglia ME, Keller MP, Coon JJ, Attie AD. Phosphorylation and degradation of tomosyn-2 de-represses insulin secretion. The Journal of Biological Chemistry. 289: 25276-86. PMID 25002582 DOI: 10.1074/jbc.M114.575985  0.56
2014 Soni MS, Rabaglia ME, Bhatnagar S, Shang J, Ilkayeva O, Mynatt R, Zhou YP, Schadt EE, Thornberry NA, Muoio DM, Keller MP, Attie AD. Downregulation of carnitine acyl-carnitine translocase by miRNAs 132 and 212 amplifies glucose-stimulated insulin secretion. Diabetes. 63: 3805-14. PMID 24969106 DOI: 10.2337/db13-1677  0.56
2014 Martin OJ, Lai L, Soundarapandian MM, Leone TC, Zorzano A, Keller MP, Attie AD, Muoio DM, Kelly DP. A role for peroxisome proliferator-activated receptor γ coactivator-1 in the control of mitochondrial dynamics during postnatal cardiac growth. Circulation Research. 114: 626-36. PMID 24366168 DOI: 10.1161/CIRCRESAHA.114.302562  0.44
2014 Ulbrich A, Merrill AE, Hebert AS, Westphall MS, Keller MP, Attie AD, Coon JJ. Neutron-encoded protein quantification by peptide carbamylation. Journal of the American Society For Mass Spectrometry. 25: 6-9. PMID 24178922 DOI: 10.1007/s13361-013-0765-z  0.44
2013 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, et al. Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation. The Journal of Biological Chemistry. 288: 26209-19. PMID 23864654 DOI: 10.1074/jbc.M113.483396  0.56
2013 Kimple ME, Keller MP, Rabaglia MR, Pasker RL, Neuman JC, Truchan NA, Brar HK, Attie AD. Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin secretion. Diabetes. 62: 1904-12. PMID 23349487 DOI: 10.2337/db12-0769  0.44
2013 Neto EC, Broman AT, Keller MP, Attie AD, Zhang B, Zhu J, Yandell BS. Modeling causality for pairs of phenotypes in system genetics. Genetics. 193: 1003-13. PMID 23288936 DOI: 10.1534/genetics.112.147124  0.56
2012 Tu Z, Keller MP, Zhang C, Rabaglia ME, Greenawalt DM, Yang X, Wang IM, Dai H, Bruss MD, Lum PY, Zhou YP, Kemp DM, Kendziorski C, Yandell BS, Attie AD, et al. Integrative analysis of a cross-loci regulation network identifies App as a gene regulating insulin secretion from pancreatic islets. Plos Genetics. 8: e1003107. PMID 23236292 DOI: 10.1371/journal.pgen.1003107  0.56
2012 Grimsrud PA, Carson JJ, Hebert AS, Hubler SL, Niemi NM, Bailey DJ, Jochem A, Stapleton DS, Keller MP, Westphall MS, Yandell BS, Attie AD, Coon JJ, Pagliarini DJ. A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis. Cell Metabolism. 16: 672-83. PMID 23140645 DOI: 10.1016/j.cmet.2012.10.004  0.56
2012 Neto EC, Keller MP, Broman AF, Attie AD, Jansen RC, Broman KW, Yandell BS. Quantile-based permutation thresholds for quantitative trait loci hotspots. Genetics. 191: 1355-65. PMID 22661325 DOI: 10.1534/genetics.112.139451  0.56
2012 Wang CY, Stapleton DS, Schueler KL, Rabaglia ME, Oler AT, Keller MP, Kendziorski CM, Broman KW, Yandell BS, Schadt EE, Attie AD. Tsc2, a positional candidate gene underlying a quantitative trait locus for hepatic steatosis. Journal of Lipid Research. 53: 1493-501. PMID 22628617 DOI: 10.1194/jlr.M025239  0.56
2012 Casellas J, Gularte RJ, Farber CR, Varona L, Mehrabian M, Schadt EE, Lusis AJ, Attie AD, Yandell BS, Medrano JF. Genome scans for transmission ratio distortion regions in mice. Genetics. 191: 247-59. PMID 22367040 DOI: 10.1534/genetics.111.135988  0.56
2011 Bhatnagar S, Oler AT, Rabaglia ME, Stapleton DS, Schueler KL, Truchan NA, Worzella SL, Stoehr JP, Clee SM, Yandell BS, Keller MP, Thurmond DC, Attie AD. Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion. Plos Genetics. 7: e1002323. PMID 21998599 DOI: 10.1371/journal.pgen.1002323  0.56
2011 Raines SM, Richards OC, Schneider LR, Schueler KL, Rabaglia ME, Oler AT, Stapleton DS, Genové G, Dawson JA, Betsholtz C, Attie AD. Loss of PDGF-B activity increases hepatic vascular permeability and enhances insulin sensitivity. American Journal of Physiology. Endocrinology and Metabolism. 301: E517-26. PMID 21673305 DOI: 10.1152/ajpendo.00241.2011  0.92
2011 Wang P, Dawson JA, Keller MP, Yandell BS, Thornberry NA, Zhang BB, Wang IM, Schadt EE, Attie AD, Kendziorski C. A model selection approach for expression quantitative trait loci (eQTL) mapping. Genetics. 187: 611-21. PMID 21115971 DOI: 10.1534/genetics.110.122796  0.56
2010 Lavine JA, Attie AD. Gastrointestinal hormones and the regulation of β-cell mass. Annals of the New York Academy of Sciences. 1212: 41-58. PMID 21039588 DOI: 10.1111/j.1749-6632.2010.05802.x  0.96
2010 Lane RF, Raines SM, Steele JW, Ehrlich ME, Lah JA, Small SA, Tanzi RE, Attie AD, Gandy S. Diabetes-associated SorCS1 regulates Alzheimer's amyloid-beta metabolism: evidence for involvement of SorL1 and the retromer complex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13110-5. PMID 20881129 DOI: 10.1523/JNEUROSCI.3872-10.2010  0.92
2010 Attie AD, Keller MP. Gene co-expression modules and type 2 diabetes. Results and Problems in Cell Differentiation. 52: 47-56. PMID 20865371 DOI: 10.1007/978-3-642-14426-4_5  0.44
2010 Babak T, Garrett-Engele P, Armour CD, Raymond CK, Keller MP, Chen R, Rohl CA, Johnson JM, Attie AD, Fraser HB, Schadt EE. Genetic validation of whole-transcriptome sequencing for mapping expression affected by cis-regulatory variation. Bmc Genomics. 11: 473. PMID 20707912 DOI: 10.1186/1471-2164-11-473  0.52
2010 Davis DB, Lavine JA, Suhonen JI, Krautkramer KA, Rabaglia ME, Sperger JM, Fernandez LA, Yandell BS, Keller MP, Wang IM, Schadt EE, Attie AD. FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation. Molecular Endocrinology (Baltimore, Md.). 24: 1822-34. PMID 20660304 DOI: 10.1210/me.2010-0082  0.96
2010 Hudkins KL, Pichaiwong W, Wietecha T, Kowalewska J, Banas MC, Spencer MW, Mühlfeld A, Koelling M, Pippin JW, Shankland SJ, Askari B, Rabaglia ME, Keller MP, Attie AD, Alpers CE. BTBR Ob/Ob mutant mice model progressive diabetic nephropathy. Journal of the American Society of Nephrology : Jasn. 21: 1533-42. PMID 20634301 DOI: 10.1681/ASN.2009121290  0.56
2010 Lavine JA, Raess PW, Stapleton DS, Rabaglia ME, Suhonen JI, Schueler KL, Koltes JE, Dawson JA, Yandell BS, Samuelson LC, Beinfeld MC, Davis DB, Hellerstein MK, Keller MP, Attie AD. Cholecystokinin is up-regulated in obese mouse islets and expands beta-cell mass by increasing beta-cell survival. Endocrinology. 151: 3577-88. PMID 20534724 DOI: 10.1210/en.2010-0233  0.96
2010 Zhong H, Beaulaurier J, Lum PY, Molony C, Yang X, Macneil DJ, Weingarth DT, Zhang B, Greenawalt D, Dobrin R, Hao K, Woo S, Fabre-Suver C, Qian S, Tota MR, ... ... Attie AD, et al. Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes. Plos Genetics. 6: e1000932. PMID 20463879 DOI: 10.1371/journal.pgen.1000932  0.56
2010 Keller MP, Attie AD. Physiological insights gained from gene expression analysis in obesity and diabetes. Annual Review of Nutrition. 30: 341-64. PMID 20415584 DOI: 10.1146/annurev.nutr.012809.104747  0.44
2010 Newgard CB, Attie AD. Getting biological about the genetics of diabetes. Nature Medicine. 16: 388-91. PMID 20376050 DOI: 10.1038/nm0410-388  0.44
2010 Richards OC, Raines SM, Attie AD. The role of blood vessels, endothelial cells, and vascular pericytes in insulin secretion and peripheral insulin action. Endocrine Reviews. 31: 343-63. PMID 20164242 DOI: 10.1210/er.2009-0035  0.92
2010 Lavine JA, Raess PW, Davis DB, Rabaglia ME, Presley BK, Keller MP, Beinfeld MC, Kopin AS, Newgard CB, Attie AD. Contamination with E1A-positive wild-type adenovirus accounts for species-specific stimulation of islet cell proliferation by CCK: a cautionary note. Molecular Endocrinology (Baltimore, Md.). 24: 464-7. PMID 20081104 DOI: 10.1210/me.2009-0384  0.96
2009 Zhao E, Keller MP, Rabaglia ME, Oler AT, Stapleton DS, Schueler KL, Neto EC, Moon JY, Wang P, Wang IM, Lum PY, Ivanovska I, Cleary M, Greenawalt D, Tsang J, ... ... Attie AD, et al. Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 476-85. PMID 19727952 DOI: 10.1007/s00335-009-9217-2  0.56
2009 Rieck S, White P, Schug J, Fox AJ, Smirnova O, Gao N, Gupta RK, Wang ZV, Scherer PE, Keller MP, Attie AD, Kaestner KH. The transcriptional response of the islet to pregnancy in mice. Molecular Endocrinology (Baltimore, Md.). 23: 1702-12. PMID 19574445 DOI: 10.1210/me.2009-0144  0.44
2008 Attie AD, Witztum JL, Edwards PA, Lusis JA. In memoriam: Roger A. Davis (1945-2008). Journal of Lipid Research. 49: 2279-80. PMID 19123270 DOI: 10.1194/jlr.E800017-JLR200  1
2008 Lavine JA, Raess PW, Davis DB, Rabaglia ME, Presley BK, Keller MP, Beinfeld MC, Kopin AS, Newgard CB, Attie AD. Overexpression of pre-pro-cholecystokinin stimulates beta-cell proliferation in mouse and human islets with retention of islet function. Molecular Endocrinology (Baltimore, Md.). 22: 2716-28. PMID 18845673 DOI: 10.1210/me.2008-0255  0.96
2008 Chen J, Hui ST, Couto FM, Mungrue IN, Davis DB, Attie AD, Lusis AJ, Davis RA, Shalev A. Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3581-94. PMID 18552236 DOI: 10.1096/fj.08-111690  0.48
2008 Chaibub Neto E, Ferrara CT, Attie AD, Yandell BS. Inferring causal phenotype networks from segregating populations. Genetics. 179: 1089-100. PMID 18505877 DOI: 10.1534/genetics.107.085167  0.56
2008 Flowers MT, Keller MP, Choi Y, Lan H, Kendziorski C, Ntambi JM, Attie AD. Liver gene expression analysis reveals endoplasmic reticulum stress and metabolic dysfunction in SCD1-deficient mice fed a very low-fat diet. Physiological Genomics. 33: 361-72. PMID 18381840 DOI: 10.1152/physiolgenomics.00139.2007  0.52
2008 Ferrara CT, Wang P, Neto EC, Stevens RD, Bain JR, Wenner BR, Ilkayeva OR, Keller MP, Blasiole DA, Kendziorski C, Yandell BS, Newgard CB, Attie AD. Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling. Plos Genetics. 4: e1000034. PMID 18369453 DOI: 10.1371/journal.pgen.1000034  0.56
2008 Davis RA, Attie AD. Deletion of the ileal basolateral bile acid transporter identifies the cellular sentinels that regulate the bile acid pool. Proceedings of the National Academy of Sciences of the United States of America. 105: 4965-6. PMID 18362334 DOI: 10.1073/pnas.0801194105  0.48
2008 Keller MP, Choi Y, Wang P, Davis DB, Rabaglia ME, Oler AT, Stapleton DS, Argmann C, Schueler KL, Edwards S, Steinberg HA, Chaibub Neto E, Kleinhanz R, Turner S, Hellerstein MK, ... ... Attie AD, et al. A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility. Genome Research. 18: 706-16. PMID 18347327 DOI: 10.1101/gr.074914.107  0.56
2008 Oler AT, Attie AD. A rapid, microplate SNP genotype assay for the leptinob allele. Journal of Lipid Research. 49: 1126-9. PMID 18272929 DOI: 10.1194/jlr.D800002-JLR200  0.48
2008 Blasiole DA, Oler AT, Attie AD. Regulation of ApoB secretion by the low density lipoprotein receptor requires exit from the endoplasmic reticulum and interaction with ApoE or ApoB. The Journal of Biological Chemistry. 283: 11374-81. PMID 18272520 DOI: 10.1074/jbc.M710457200  0.48
2007 Attie AD, Flowers MT, Flowers JB, Groen AK, Kuipers F, Ntambi JM. Stearoyl-CoA desaturase deficiency, hypercholesterolaemia, cholestasis and diabetes. Novartis Foundation Symposium. 286: 47-53; discussion 54. PMID 18269173  0.48
2007 Blasiole DA, Davis RA, Attie AD. The physiological and molecular regulation of lipoprotein assembly and secretion. Molecular Biosystems. 3: 608-19. PMID 17700861 DOI: 10.1039/b700706j  0.48
2007 Attie AD, Flowers MT, Flowers JB, Groen AK, Kuipers F, Ntambi JM. Stearoyl-CoA desaturase deficiency, hypercholesterolemia, cholestasis, and diabetes. Nutrition Reviews. 65: S35-8. PMID 17605312  0.48
2007 Nassoury N, Blasiole DA, Tebon Oler A, Benjannet S, Hamelin J, Poupon V, McPherson PS, Attie AD, Prat A, Seidah NG. The cellular trafficking of the secretory proprotein convertase PCSK9 and its dependence on the LDLR. Traffic (Copenhagen, Denmark). 8: 718-32. PMID 17461796 DOI: 10.1111/j.1600-0854.2007.00562.x  0.48
2007 Goodarzi MO, Lehman DM, Taylor KD, Guo X, Cui J, Quiñones MJ, Clee SM, Yandell BS, Blangero J, Hsueh WA, Attie AD, Stern MP, Rotter JI. SORCS1: a novel human type 2 diabetes susceptibility gene suggested by the mouse. Diabetes. 56: 1922-9. PMID 17426289 DOI: 10.2337/db06-1677  0.56
2007 Flowers JB, Rabaglia ME, Schueler KL, Flowers MT, Lan H, Keller MP, Ntambi JM, Attie AD. Loss of stearoyl-CoA desaturase-1 improves insulin sensitivity in lean mice but worsens diabetes in leptin-deficient obese mice. Diabetes. 56: 1228-39. PMID 17369521 DOI: 10.2337/db06-1142  0.56
2007 Flowers JB, Oler AT, Nadler ST, Choi Y, Schueler KL, Yandell BS, Kendziorski CM, Attie AD. Abdominal obesity in BTBR male mice is associated with peripheral but not hepatic insulin resistance. American Journal of Physiology. Endocrinology and Metabolism. 292: E936-45. PMID 17132824 DOI: 10.1152/ajpendo.00370.2006  1
2007 Clee SM, Attie AD. The genetic landscape of type 2 diabetes in mice. Endocrine Reviews. 28: 48-83. PMID 17018838 DOI: 10.1210/er.2006-0035  0.32
2006 Flowers MT, Groen AK, Oler AT, Keller MP, Choi Y, Schueler KL, Richards OC, Lan H, Miyazaki M, Kuipers F, Kendziorski CM, Ntambi JM, Attie AD. Cholestasis and hypercholesterolemia in SCD1-deficient mice fed a low-fat, high-carbohydrate diet. Journal of Lipid Research. 47: 2668-80. PMID 17005996 DOI: 10.1194/jlr.M600203-JLR200  0.92
2006 Clee SM, Yandell BS, Schueler KM, Rabaglia ME, Richards OC, Raines SM, Kabara EA, Klass DM, Mui ET, Stapleton DS, Gray-Keller MP, Young MB, Stoehr JP, Lan H, Boronenkov I, ... ... Attie AD, et al. Positional cloning of Sorcs1, a type 2 diabetes quantitative trait locus. Nature Genetics. 38: 688-93. PMID 16682971 DOI: 10.1038/ng1796  0.92
2006 Lan H, Chen M, Flowers JB, Yandell BS, Stapleton DS, Mata CM, Mui ET, Flowers MT, Schueler KL, Manly KF, Williams RW, Kendziorski C, Attie AD. Combined expression trait correlations and expression quantitative trait locus mapping. Plos Genetics. 2: e6. PMID 16424919 DOI: 10.1371/journal.pgen.0020006  0.56
2005 Clee SM, Nadler ST, Attie AD. Genetic and genomic studies of the BTBR ob/ob mouse model of type 2 diabetes. American Journal of Therapeutics. 12: 491-8. PMID 16280642  1
2005 Rabaglia ME, Gray-Keller MP, Frey BL, Shortreed MR, Smith LM, Attie AD. Alpha-Ketoisocaproate-induced hypersecretion of insulin by islets from diabetes-susceptible mice. American Journal of Physiology. Endocrinology and Metabolism. 289: E218-24. PMID 15741243 DOI: 10.1152/ajpendo.00573.2004  0.56
2005 Minn AH, Lan H, Rabaglia ME, Harlan DM, Peculis BA, Attie AD, Shalev A. Increased insulin translation from an insulin splice-variant overexpressed in diabetes, obesity, and insulin resistance. Molecular Endocrinology (Baltimore, Md.). 19: 794-803. PMID 15550470 DOI: 10.1210/me.2004-0119  0.56
2004 Jin C, Lan H, Attie AD, Churchill GA, Bulutuglo D, Yandell BS. Selective phenotyping for increased efficiency in genetic mapping studies. Genetics. 168: 2285-93. PMID 15611192 DOI: 10.1534/genetics.104.027524  0.56
2004 Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD, Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ, Buckler E, et al. The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nature Genetics. 36: 1133-7. PMID 15514660 DOI: 10.1038/ng1104-1133  0.48
2004 Benjannet S, Rhainds D, Essalmani R, Mayne J, Wickham L, Jin W, Asselin MC, Hamelin J, Varret M, Allard D, Trillard M, Abifadel M, Tebon A, Attie AD, Rader DJ, et al. NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol. The Journal of Biological Chemistry. 279: 48865-75. PMID 15358785 DOI: 10.1074/jbc.M409699200  0.4
2004 Hui TY, Sheth SS, Diffley JM, Potter DW, Lusis AJ, Attie AD, Davis RA. Mice lacking thioredoxin-interacting protein provide evidence linking cellular redox state to appropriate response to nutritional signals. The Journal of Biological Chemistry. 279: 24387-93. PMID 15047687 DOI: 10.1074/jbc.M401280200  0.48
2004 Stoehr JP, Byers JE, Clee SM, Lan H, Boronenkov IV, Schueler KL, Yandell BS, Attie AD. Identification of major quantitative trait loci controlling body weight variation in ob/ob mice. Diabetes. 53: 245-9. PMID 14693723  0.56
2004 Lan H, Rabaglia ME, Schueler KL, Mata C, Yandell BS, Attie AD. Distinguishing covariation from causation in diabetes: a lesson from the protein disulfide isomerase mRNA abundance trait. Diabetes. 53: 240-4. PMID 14693722  0.56
2003 Lan H, Stoehr JP, Nadler ST, Schueler KL, Yandell BS, Attie AD. Dimension reduction for mapping mRNA abundance as quantitative traits. Genetics. 164: 1607-14. PMID 12930764  1
2003 Attie AD, Kendziorski CM. PGC-1alpha at the crossroads of type 2 diabetes. Nature Genetics. 34: 244-5. PMID 12833045 DOI: 10.1038/ng0703-244  0.36
2003 Lan H, Rabaglia ME, Stoehr JP, Nadler ST, Schueler KL, Zou F, Yandell BS, Attie AD. Gene expression profiles of nondiabetic and diabetic obese mice suggest a role of hepatic lipogenic capacity in diabetes susceptibility. Diabetes. 52: 688-700. PMID 12606510  1
2003 Mulligan JD, Flowers MT, Tebon A, Bitgood JJ, Wellington C, Hayden MR, Attie AD. ABCA1 is essential for efficient basolateral cholesterol efflux during the absorption of dietary cholesterol in chickens. The Journal of Biological Chemistry. 278: 13356-66. PMID 12551945 DOI: 10.1074/jbc.M212377200  0.48
2002 Attie AD, Krauss RM, Gray-Keller MP, Brownlie A, Miyazaki M, Kastelein JJ, Lusis AJ, Stalenhoef AF, Stoehr JP, Hayden MR, Ntambi JM. Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia. Journal of Lipid Research. 43: 1899-907. PMID 12401889 DOI: 10.1194/jlr.M200189-JLR200  0.56
2002 Attie AD, Hamon Y, Brooks-Wilson AR, Gray-Keller MP, MacDonald ML, Rigot V, Tebon A, Zhang LH, Mulligan JD, Singaraja RR, Bitgood JJ, Cook ME, Kastelein JJ, Chimini G, Hayden MR. Identification and functional analysis of a naturally occurring E89K mutation in the ABCA1 gene of the WHAM chicken. Journal of Lipid Research. 43: 1610-7. PMID 12364545 DOI: 10.1194/jlr.M200223-JLR200  0.4
2002 Ntambi JM, Miyazaki M, Stoehr JP, Lan H, Kendziorski CM, Yandell BS, Song Y, Cohen P, Friedman JM, Attie AD. Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity. Proceedings of the National Academy of Sciences of the United States of America. 99: 11482-6. PMID 12177411 DOI: 10.1073/pnas.132384699  0.56
2002 Gillian-Daniel DL, Bates PW, Tebon A, Attie AD. Endoplasmic reticulum localization of the low density lipoprotein receptor mediates presecretory degradation of apolipoprotein B. Proceedings of the National Academy of Sciences of the United States of America. 99: 4337-42. PMID 11904390 DOI: 10.1073/pnas.072557199  0.4
2001 Attie AD, Kastelein JP, Hayden MR. Pivotal role of ABCA1 in reverse cholesterol transport influencing HLD levels and susceptibility to atherosclerosis Journal of Lipid Research. 42: 1717-1726. PMID 11714841  1
2001 Nadler ST, Stoehr JP, Rabaglia ME, Schueler KL, Birnbaum MJ, Attie AD. Normal Akt/PKB with reduced PI3K activation in insulin-resistant mice American Journal of Physiology - Endocrinology and Metabolism. 281: E1249-E1254. PMID 11701440  1
2001 Nadler ST, Attie AD. Please pass the chips: genomic insights into obesity and diabetes. The Journal of Nutrition. 131: 2078-81. PMID 11481397  1
2000 Stoehr JP, Nadler ST, Schueler KL, Rabaglia ME, Yandell BS, Metz SA, Attie AD. Genetic obesity unmasks nonlinear interactions between murine type 2 diabetes susceptibility loci. Diabetes. 49: 1946-54. PMID 11078464  1
2000 Nadler ST, Stoehr JP, Schueler KL, Tanimoto G, Yandell BS, Attie AD. The expression of adipogenic genes is decreased in obesity and diabetes mellitus. Proceedings of the National Academy of Sciences of the United States of America. 97: 11371-6. PMID 11027337 DOI: 10.1073/pnas.97.21.11371  1
2000 Miyazaki M, Kim YC, Gray-Keller MP, Attie AD, Ntambi JM. The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1. The Journal of Biological Chemistry. 275: 30132-8. PMID 10899171 DOI: 10.1074/jbc.M005488200  0.48
2000 Twisk J, Gillian-Daniel DL, Tebon A, Wang L, Barrett PH, Attie AD. The role of the LDL receptor in apolipoprotein B secretion. The Journal of Clinical Investigation. 105: 521-32. PMID 10683382 DOI: 10.1172/JCI8623  1
1999 Grunwald KA, Schueler K, Uelmen PJ, Lipton BA, Kaiser M, Buhman K, Attie AD. Identification of a novel Arg-->Cys mutation in the LDL receptor that contributes to spontaneous hypercholesterolemia in pigs. Journal of Lipid Research. 40: 475-85. PMID 10064736  1
1997 Ranheim T, Dumke C, Schueler KL, Cartee GD, Attie AD. Interaction between BTBR and C57BL/6J genomes produces an insulin resistance syndrome in (BTBR x C57BL/6J) F1 mice Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 3286-3293. PMID 9409324 DOI: 10.1161/01.ATV.17.11.3286  1
1997 Wang L, Fast DG, Attie AD. The enzymatic and non-enzymatic roles of protein-disulfide isomerase in apolipoprotein B secretion. The Journal of Biological Chemistry. 272: 27644-51. PMID 9346903  1
1996 Dirlam KA, Gretch DG, LaCount DJ, Sturley SL, Attie AD. Expression and characterization of a truncated, soluble, low-density lipoprotein receptor Protein Expression and Purification. 8: 489-500. PMID 8954898  1
1996 Gretch DG, Sturley SL, Wang L, Lipton BA, Dunning A, Grunwald KA, Wetterau JR, Yao Z, Talmud P, Attie AD. The amino terminus of apolipoprotein B is necessary but not sufficient for microsomal triglyceride transfer protein responsiveness. The Journal of Biological Chemistry. 271: 8682-91. PMID 8621500 DOI: 10.1074/jbc.271.15.8682  1
1995 Gretch DG, Sturley SL, Attie AD. Human apolipoprotein E mediates processive buoyant lipoprotein formation in insect larvae. Biochemistry. 34: 545-52. PMID 7819248  1
1995 Choi SY, Sivaram P, Walker DE, Curtiss LK, Gretch DG, Sturley SL, Attie AD, Deckelbaum RJ, Goldberg IJ. Lipoprotein lipase association with lipoproteins involves protein-protein interaction with apolipoprotein B. The Journal of Biological Chemistry. 270: 8081-6. PMID 7713910  1
1994 Aiello RJ, Nevin DN, Ebert DL, Uelmen PJ, Kaiser ME, MacCluer JW, Blangero J, Dyer TD, Attie AD. Apolipoprotein B and a second major gene locus contribute to phenotypic variation of spontaneous hypercholesterolemia in pigs Arteriosclerosis, Thrombosis, and Vascular Biology. 14: 409-419. PMID 8123646  1
1994 Sturley SL, Talmud PJ, Brasseur R, Culbertson MR, Humphries SE, Attie AD. Human apolipoprotein B signal sequence variants confer a secretion-defective phenotype when expressed in yeast. The Journal of Biological Chemistry. 269: 21670-5. PMID 8063810  1
1994 Schreyer SA, Hart LK, Attie AD. Hypercatabolism of lipoprotein-free apolipoprotein A-I in HDL-deficient mutant chickens. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology / American Heart Association. 14: 2053-9. PMID 7981195  1
1993 Kaiser ME, Nevin DN, Sturley SL, Purtell C, Attie AD. Determination of pig apolipoprotein B genotype by gene amplification and restriction fragment length polymorphism analysis. Animal Genetics. 24: 117-20. PMID 8101055  1
1992 Cooper ST, Aiello RJ, Checovich WJ, Attie AD. Low density lipoprotein heterogeneity in spontaneously hypercholesterolemic pigs. Molecular and Cellular Biochemistry. 113: 133-40. PMID 1518504 DOI: 10.1007/BF00231533  1
1991 Checovich WJ, Aiello RJ, Attie AD. Overproduction of a buoyant low density lipoprotein subspecies in spontaneously hypercholesterolemic mutant pigs. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology / American Heart Association. 11: 351-61. PMID 1998653  1
1991 Gretch DG, Sturley SL, Friesen PD, Beckage NE, Attie AD. Baculovirus-mediated expression of human apolipoprotein E in Manduca sexta larvae generates particles that bind to the low density lipoprotein receptor Proceedings of the National Academy of Sciences of the United States of America. 88: 8530-8533. PMID 1924311 DOI: 10.1073/pnas.88.19.8530  1
1991 Sturley SL, Culbertson MR, Attie AD. Secretion and lipid association of human apolipoprotein E in Saccharomyces cerevisiae requires a host mutation in sterol esterification and uptake. The Journal of Biological Chemistry. 266: 16273-6. PMID 1885560  1
1990 Poernama F, Schreyer SA, Bitgood JJ, Cook ME, Attie AD. Spontaneous high density lipoprotein deficiency syndrome associated with a Z-linked mutation in chickens. Journal of Lipid Research. 31: 955-63. PMID 2373963  0.4
1988 Checovich WJ, Fitch WL, Krauss RM, Smith MP, Rapacz J, Smith CL, Attie AD. Defective catabolism and abnormal composition of low-density lipoproteins from mutant pigs with hypercholesterolemia Biochemistry. 27: 1934-1941. PMID 3378039 DOI: 10.1021/bi00406a020  1
1983 Pittman RC, Carew TE, Glass CK, Green SR, Taylor CA, Attie AD. A radioiodinated, intracellularly trapped ligand for determining the sites of plasma protein degradation in vivo. The Biochemical Journal. 212: 791-800. PMID 6882394 DOI: 10.1042/bj2120791  1
1982 Pittman RC, Attie AD, Carew TE, Steinberg D. Tissue sites of catabolism of rat and human low density lipoproteins in rats. Biochimica Et Biophysica Acta. 710: 7-14. PMID 7055596 DOI: 10.1016/0005-2760(82)90183-7  1
1982 Pittman RC, Carew TE, Attie AD, Witztum JL, Watanabe Y, Steinberg D. Receptor-dependent and receptor-independent degradation of low density lipoprotein in normal rabbits and in receptor-deficient mutant rabbits. The Journal of Biological Chemistry. 257: 7994-8000. PMID 6282866  1
1982 Attie AD, Pittman RC, Steinberg D. Hepatic catabolism of low density lipoprotein: mechanisms and metabolic consequences. Hepatology (Baltimore, Md.). 2: 269-81. PMID 6279484  1
1981 Attie AD, Pittman RC, Watanabe Y, Steinberg D. Low density lipoprotein receptor deficiency in cultured hepatocytes of the WHHL rabbit. Further evidence of two pathways for catabolism of exogenous proteins. The Journal of Biological Chemistry. 256: 9789-92. PMID 6268629  1
1981 Drevon CA, Attie AD, Pangburn SH, Steinberg D. Metabolism of homologous and heterologous lipoproteins by cultured rat and human skin fibroblasts. Journal of Lipid Research. 22: 37-46. PMID 6260882  1
1980 Attie AD, Pittman RC, Steinberg D. Metabolism of native and of lactosylated human low density lipoprotein: evidence for two pathways for catabolism of exogenous proteins in rat hepatocytes. Proceedings of the National Academy of Sciences of the United States of America. 77: 5923-7. PMID 6160586  1
1979 Pittman RC, Attie AD, Carew TE, Steinberg D. Tissue sites of degradation of low density lipoprotein: application of a method for determining the fate of plasma proteins. Proceedings of the National Academy of Sciences of the United States of America. 76: 5345-9. PMID 228286  1
1979 Attie AD, Weinstein DB, Freeze HH, Pittman RC, Steinberg D. Unaltered catabolism of desialylated low-density lipoprotein in the pig and in cultured rat hepatocytes. The Biochemical Journal. 180: 647-54. PMID 90503  1
1979 Pittman RC, Green SR, Attie AD, Steinberg D. Radiolabeled sucrose covalently linked to protein. A device for quantifying degradation of plasma proteins catabolized by lysosomal mechanisms. The Journal of Biological Chemistry. 254: 6876-9. PMID 88445  1
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