Dirk J. Snyders - Publications

Universiteit Antwerpen (Belgium) 

40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Van Theemsche KM, Van de Sande DV, Snyders DJ, Labro AJ. Hydrophobic Drug/Toxin Binding Sites in Voltage-Dependent K and Na Channels. Frontiers in Pharmacology. 11: 735. PMID 32499709 DOI: 10.3389/fphar.2020.00735  0.84
2020 Coonen L, Mayeur E, De Neuter N, Snyders DJ, Cuello LG, Labro AJ. The Selectivity Filter Is Involved in the U-Type Inactivation Process of Kv2.1 and Kv3.1 Channels. Biophysical Journal. PMID 32365329 DOI: 10.1016/j.bpj.2020.03.032  0.84
2020 Möller L, Regnier G, Labro AJ, Blunck R, Snyders DJ. Determining the correct stoichiometry of Kv2.1/Kv6.4 heterotetramers, functional in multiple stoichiometrical configurations. Proceedings of the National Academy of Sciences of the United States of America. PMID 32284408 DOI: 10.1073/pnas.1916166117  0.84
2019 Van de Sande DV, Kopljar I, Teisman A, Gallacher DJ, Snyders DJ, Lu HR, Labro AJ. Pharmacological Profile of the Sodium Current in Human Stem Cell-Derived Cardiomyocytes Compares to Heterologous Nav1.5+β1 Model. Frontiers in Pharmacology. 10: 1374. PMID 31920633 DOI: 10.3389/fphar.2019.01374  0.84
2017 Bocksteins E, Snyders DJ, Holmgren M. Independent movement of the voltage sensors in KV2.1/KV6.4 heterotetramers. Scientific Reports. 7: 41646. PMID 28139741 DOI: 10.1038/srep41646  1
2016 Stas JI, Bocksteins E, Jensen CS, Schmitt N, Snyders DJ. The anticonvulsant retigabine suppresses neuronal KV2-mediated currents. Scientific Reports. 6: 35080. PMID 27734968 DOI: 10.1038/srep35080  1
2016 Regnier G, Bocksteins E, Marei WF, Pintelon I, Timmermans JP, Leroy JL, Snyders DJ. Targeted deletion of the Kv6.4 subunit causes male sterility due to disturbed spermiogenesis. Reproduction, Fertility, and Development. PMID 27677211 DOI: 10.1071/RD16075  1
2016 Martínez-Morales E, Kopljar I, Rainier JD, Tytgat J, Snyders DJ, Labro AJ. Gambierol and n-alkanols inhibit Shaker Kv channel via distinct binding sites outside the K(+) pore. Toxicon : Official Journal of the International Society On Toxinology. PMID 27475861 DOI: 10.1016/j.toxicon.2016.07.017  0.84
2016 Hassiki R, Labro AJ, Benlasfar Z, Vincke C, Somia M, Ayeb ME, Muyldermans S, Snyders DJ, Bouhaouala-Zahar B. Dromedary immune response and specific Kv2.1 antibody generation using a specific immunization approach. International Journal of Biological Macromolecules. PMID 27320844 DOI: 10.1016/j.ijbiomac.2016.06.031  0.84
2016 Regnier G, Bocksteins E, Van de Vijver G, Snyders DJ, van Bogaert PP. The contribution of Kv2.2-mediated currents decreases during the postnatal development of mouse dorsal root ganglion neurons. Physiological Reports. 4. PMID 27033450 DOI: 10.14814/phy2.12731  1
2016 Kopljar I, Grottesi A, de Block T, Rainier JD, Tytgat J, Labro AJ, Snyders DJ. Voltage-sensor conformation shapes the intra-membrane drug binding site that determines gambierol affinity in Kv channels. Neuropharmacology. PMID 26956727 DOI: 10.1016/j.neuropharm.2016.03.010  0.84
2015 Labro AJ, Priest MF, Lacroix JJ, Snyders DJ, Bezanilla F. Kv3.1 uses a timely resurgent K(+) current to secure action potential repolarization. Nature Communications. 6: 10173. PMID 26673941 DOI: 10.1038/ncomms10173  1
2015 Martínez-Morales E, Kopljar I, Snyders DJ, Labro AJ. Alkanols inhibit voltage-gated K(+) channels via a distinct gating modifying mechanism that prevents gate opening. Scientific Reports. 5: 17402. PMID 26616025 DOI: 10.1038/srep17402  0.84
2015 Stas JI, Bocksteins E, Labro AJ, Snyders DJ. Modulation of Closed-State Inactivation in Kv2.1/Kv6.4 Heterotetramers as Mechanism for 4-AP Induced Potentiation. Plos One. 10: e0141349. PMID 26505474 DOI: 10.1371/journal.pone.0141349  1
2014 Bocksteins E, Mayeur E, Van Tilborg A, Regnier G, Timmermans JP, Snyders DJ. The subfamily-specific interaction between Kv2.1 and Kv6.4 subunits is determined by interactions between the N- and C-termini. Plos One. 9: e98960. PMID 24901643 DOI: 10.1371/journal.pone.0098960  1
2014 Martinez-Morales E, Snyders DJ, Labro AJ. Mutations in the S6 gate isolate a late step in the activation pathway and reduce 4-AP sensitivity in shaker K(v) channel. Biophysical Journal. 106: 134-44. PMID 24411245 DOI: 10.1016/j.bpj.2013.11.025  0.84
2013 Kopljar I, Labro AJ, de Block T, Rainier JD, Tytgat J, Snyders DJ. The ladder-shaped polyether toxin gambierol anchors the gating machinery of Kv3.1 channels in the resting state. The Journal of General Physiology. 141: 359-69. PMID 23401573 DOI: 10.1085/jgp.201210890  0.84
2012 Labro AJ, Lacroix JJ, Villalba-Galea CA, Snyders DJ, Bezanilla F. Molecular mechanism for depolarization-induced modulation of Kv channel closure. The Journal of General Physiology. 140: 481-93. PMID 23071266 DOI: 10.1085/jgp.201210817  1
2012 Labro AJ, Snyders DJ. Being flexible: the voltage-controllable activation gate of kv channels. Frontiers in Pharmacology. 3: 168. PMID 22993508 DOI: 10.3389/fphar.2012.00168  0.84
2012 Abderemane-Ali F, Es-Salah-Lamoureux Z, Delemotte L, Kasimova MA, Labro AJ, Snyders DJ, Fedida D, Tarek M, Baró I, Loussouarn G. Dual effect of phosphatidylinositol (4,5)-bisphosphate PIP(2) on Shaker K(+) [corrected] channels. The Journal of Biological Chemistry. 287: 36158-67. PMID 22932893 DOI: 10.1074/jbc.M112.382085  0.84
2012 Bocksteins E, Van de Vijver G, Van Bogaert PP, Snyders DJ. Kv3 channels contribute to the delayed rectifier current in small cultured mouse dorsal root ganglion neurons. American Journal of Physiology. Cell Physiology. 303: C406-15. PMID 22673617 DOI: 10.1152/ajpcell.00343.2011  1
2012 Bocksteins E, Labro AJ, Snyders DJ, Mohapatra DP. The electrically silent Kv6.4 subunit confers hyperpolarized gating charge movement in Kv2.1/Kv6.4 heterotetrameric channels. Plos One. 7: e37143. PMID 22615922 DOI: 10.1371/journal.pone.0037143  1
2012 Bocksteins E, Snyders DJ. Electrically silent Kv subunits: their molecular and functional characteristics. Physiology (Bethesda, Md.). 27: 73-84. PMID 22505664 DOI: 10.1152/physiol.00023.2011  1
2011 Bocksteins E, Ottschytsch N, Timmermans JP, Labro AJ, Snyders DJ. Functional interactions between residues in the S1, S4, and S5 domains of Kv2.1. European Biophysics Journal : Ebj. 40: 783-93. PMID 21455829 DOI: 10.1007/s00249-011-0694-3  1
2011 Labro AJ, Boulet IR, Choveau FS, Mayeur E, Bruyns T, Loussouarn G, Raes AL, Snyders DJ. The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure. The Journal of Biological Chemistry. 286: 717-25. PMID 21059661 DOI: 10.1074/jbc.M110.146977  1
2011 Choveau FS, Rodriguez N, Abderemane Ali F, Labro AJ, Rose T, Dahimène S, Boudin H, Le Hénaff C, Escande D, Snyders DJ, Charpentier F, Mérot J, Baró I, Loussouarn G. KCNQ1 channels voltage dependence through a voltage-dependent binding of the S4-S5 linker to the pore domain. The Journal of Biological Chemistry. 286: 707-16. PMID 20940310 DOI: 10.1074/jbc.M110.146324  1
2010 Labro AJ, Boulet IR, Timmermans JP, Ottschytsch N, Snyders DJ. The rate-dependent biophysical properties of the LQT1 H258R mutant are counteracted by a dominant negative effect on channel trafficking. Journal of Molecular and Cellular Cardiology. 48: 1096-104. PMID 19913547 DOI: 10.1016/j.yjmcc.2009.10.027  1
2009 Bocksteins E, Labro AJ, Mayeur E, Bruyns T, Timmermans JP, Adriaensen D, Snyders DJ. Conserved negative charges in the N-terminal tetramerization domain mediate efficient assembly of Kv2.1 and Kv2.1/Kv6.4 channels. The Journal of Biological Chemistry. 284: 31625-34. PMID 19717558 DOI: 10.1074/jbc.M109.039479  1
2009 Kopljar I, Labro AJ, Cuypers E, Johnson HW, Rainier JD, Tytgat J, Snyders DJ. A polyether biotoxin binding site on the lipid-exposed face of the pore domain of Kv channels revealed by the marine toxin gambierol. Proceedings of the National Academy of Sciences of the United States of America. 106: 9896-901. PMID 19482941 DOI: 10.1073/pnas.0812471106  0.84
2009 Bocksteins E, Raes AL, Van de Vijver G, Bruyns T, Van Bogaert PP, Snyders DJ. Kv2.1 and silent Kv subunits underlie the delayed rectifier K+ current in cultured small mouse DRG neurons. American Journal of Physiology. Cell Physiology. 296: C1271-8. PMID 19357235 DOI: 10.1152/ajpcell.00088.2009  1
2008 Labro AJ, Raes AL, Grottesi A, Van Hoorick D, Sansom MS, Snyders DJ. Kv channel gating requires a compatible S4-S5 linker and bottom part of S6, constrained by non-interacting residues. The Journal of General Physiology. 132: 667-80. PMID 19029374 DOI: 10.1085/jgp.200810048  0.84
2008 Labro AJ, Grottesi A, Sansom MS, Raes AL, Snyders DJ. A Kv channel with an altered activation gate sequence displays both "fast" and "slow" activation kinetics. American Journal of Physiology. Cell Physiology. 294: C1476-84. PMID 18385285 DOI: 10.1152/ajpcell.00479.2007  0.84
2008 Cuypers E, Abdel-Mottaleb Y, Kopljar I, Rainier JD, Raes AL, Snyders DJ, Tytgat J. Gambierol, a toxin produced by the dinoflagellate Gambierdiscus toxicus, is a potent blocker of voltage-gated potassium channels. Toxicon : Official Journal of the International Society On Toxinology. 51: 974-83. PMID 18313714 DOI: 10.1016/j.toxicon.2008.01.004  1
2007 Boulet IR, Labro AJ, Raes AL, Snyders DJ. Role of the S6 C-terminus in KCNQ1 channel gating. The Journal of Physiology. 585: 325-37. PMID 17932138 DOI: 10.1113/jphysiol.2007.145813  1
2006 Boulet IR, Raes AL, Ottschytsch N, Snyders DJ. Functional effects of a KCNQ1 mutation associated with the long QT syndrome. Cardiovascular Research. 70: 466-74. PMID 16564513 DOI: 10.1016/j.cardiores.2006.02.006  1
2005 Ottschytsch N, Raes AL, Timmermans JP, Snyders DJ. Domain analysis of Kv6.3, an electrically silent channel. The Journal of Physiology. 568: 737-47. PMID 16096342 DOI: 10.1113/jphysiol.2005.090142  1
2005 Labro AJ, Raes AL, Snyders DJ. Coupling of voltage sensing to channel opening reflects intrasubunit interactions in kv channels. The Journal of General Physiology. 125: 71-80. PMID 15623896 DOI: 10.1085/jgp.200409194  0.84
2003 Van Hoorick D, Raes A, Keysers W, Mayeur E, Snyders DJ. Differential modulation of Kv4 kinetics by KCHIP1 splice variants. Molecular and Cellular Neurosciences. 24: 357-66. PMID 14572458  0.44
2003 Labro AJ, Raes AL, Bellens I, Ottschytsch N, Snyders DJ. Gating of shaker-type channels requires the flexibility of S6 caused by prolines. The Journal of Biological Chemistry. 278: 50724-31. PMID 13679372 DOI: 10.1074/jbc.M306097200  1
2002 Rich TC, Yeola SW, Tamkun MM, Snyders DJ. Mutations throughout the S6 region of the hKv1.5 channel alter the stability of the activation gate. American Journal of Physiology. Cell Physiology. 282: C161-71. PMID 11742809 DOI: 10.1152/ajpcell.00232.2001  1
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