| Year | Citation | Score | |||
|---|---|---|---|---|---|
| 2011 | Labro AJ, Boulet IR, Choveau FS, Mayeur E, Bruyns T, Loussouarn G, Raes AL, Snyders DJ. The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure. The Journal of Biological Chemistry. 286: 717-25. PMID 21059661 DOI: 10.1074/Jbc.M110.146977 | 0.795 | |||
| 2010 | Labro AJ, Boulet IR, Raes AL, Snyders DJ. Substitution Scan of the S4-S5 Linker Region in KCNQ1 Channel: Structural Scaffold for Critical Protein Interactions Biophysical Journal. 98: 120a-121a. DOI: 10.1016/J.Bpj.2009.12.657 | 0.795 | |||
| 2009 | Bocksteins E, Raes AL, Van de Vijver G, Bruyns T, Van Bogaert PP, Snyders DJ. Kv2.1 and silent Kv subunits underlie the delayed rectifier K+ current in cultured small mouse DRG neurons. American Journal of Physiology. Cell Physiology. 296: C1271-8. PMID 19357235 DOI: 10.1152/Ajpcell.00088.2009 | 0.329 | |||
| 2009 | Labro AJ, Grottesi A, Raes AL, Snyders DJ. A P-helix Mutant In A Shaker-type Kv Channel Converts The Inactivated State Into A Conducting One Biophysical Journal. 96: 656a-657a. DOI: 10.1016/J.Bpj.2008.12.3468 | 0.623 | |||
| 2008 | Labro AJ, Raes AL, Grottesi A, Van Hoorick D, Sansom MS, Snyders DJ. Kv channel gating requires a compatible S4-S5 linker and bottom part of S6, constrained by non-interacting residues. The Journal of General Physiology. 132: 667-80. PMID 19029374 DOI: 10.1085/Jgp.200810048 | 0.457 | |||
| 2008 | Labro AJ, Grottesi A, Sansom MS, Raes AL, Snyders DJ. A Kv channel with an altered activation gate sequence displays both "fast" and "slow" activation kinetics. American Journal of Physiology. Cell Physiology. 294: C1476-84. PMID 18385285 DOI: 10.1152/Ajpcell.00479.2007 | 0.619 | |||
| 2008 | Cuypers E, Abdel-Mottaleb Y, Kopljar I, Rainier JD, Raes AL, Snyders DJ, Tytgat J. Gambierol, a toxin produced by the dinoflagellate Gambierdiscus toxicus, is a potent blocker of voltage-gated potassium channels. Toxicon : Official Journal of the International Society On Toxinology. 51: 974-83. PMID 18313714 DOI: 10.1016/J.Toxicon.2008.01.004 | 0.595 | |||
| 2007 | Boulet IR, Labro AJ, Raes AL, Snyders DJ. Role of the S6 C-terminus in KCNQ1 channel gating. The Journal of Physiology. 585: 325-37. PMID 17932138 DOI: 10.1113/Jphysiol.2007.145813 | 0.806 | |||
| 2007 | Van Hoorick D, Raes A, Snyders DJ. The aromatic cluster in KCHIP1b affects Kv4 inactivation gating. The Journal of Physiology. 583: 959-69. PMID 17640927 DOI: 10.1113/Jphysiol.2007.139550 | 0.376 | |||
| 2007 | Saenen JB, Paulussen AD, Jongbloed RJ, Marcelis CL, Gilissen RA, Aerssens J, Snyders DJ, Raes AL. A single hERG mutation underlying a spectrum of acquired and congenital long QT syndrome phenotypes. Journal of Molecular and Cellular Cardiology. 43: 63-72. PMID 17531263 DOI: 10.1016/J.Yjmcc.2007.04.012 | 0.439 | |||
| 2006 | Saenen JB, Labro AJ, Raes A, Snyders DJ. Modulation of HERG gating by a charge cluster in the N-terminal proximal domain. Biophysical Journal. 91: 4381-91. PMID 16997865 DOI: 10.1529/Biophysj.106.087247 | 0.405 | |||
| 2006 | Van Laer L, Carlsson PI, Ottschytsch N, Bondeson ML, Konings A, Vandevelde A, Dieltjens N, Fransen E, Snyders D, Borg E, Raes A, Van Camp G. The contribution of genes involved in potassium-recycling in the inner ear to noise-induced hearing loss. Human Mutation. 27: 786-95. PMID 16823764 DOI: 10.1002/Humu.20360 | 0.746 | |||
| 2006 | Boulet IR, Raes AL, Ottschytsch N, Snyders DJ. Functional effects of a KCNQ1 mutation associated with the long QT syndrome. Cardiovascular Research. 70: 466-74. PMID 16564513 DOI: 10.1016/J.Cardiores.2006.02.006 | 0.666 | |||
| 2005 | Ottschytsch N, Raes AL, Timmermans JP, Snyders DJ. Domain analysis of Kv6.3, an electrically silent channel. The Journal of Physiology. 568: 737-47. PMID 16096342 DOI: 10.1113/Jphysiol.2005.090142 | 0.787 | |||
| 2005 | Paulussen AD, Raes A, Jongbloed RJ, Gilissen RA, Wilde AA, Snyders DJ, Smeets HJ, Aerssens J. HERG mutation predicts short QT based on channel kinetics but causes long QT by heterotetrameric trafficking deficiency. Cardiovascular Research. 67: 467-75. PMID 15958262 DOI: 10.1016/J.Cardiores.2005.05.017 | 0.62 | |||
| 2005 | Labro AJ, Raes AL, Snyders DJ. Coupling of voltage sensing to channel opening reflects intrasubunit interactions in kv channels. The Journal of General Physiology. 125: 71-80. PMID 15623896 DOI: 10.1085/Jgp.200409194 | 0.664 | |||
| 2003 | Van Hoorick D, Raes A, Keysers W, Mayeur E, Snyders DJ. Differential modulation of Kv4 kinetics by KCHIP1 splice variants. Molecular and Cellular Neurosciences. 24: 357-66. PMID 14572458 DOI: 10.1016/S1044-7431(03)00174-X | 0.528 | |||
| 2003 | Labro AJ, Raes AL, Bellens I, Ottschytsch N, Snyders DJ. Gating of shaker-type channels requires the flexibility of S6 caused by prolines. The Journal of Biological Chemistry. 278: 50724-31. PMID 13679372 DOI: 10.1074/Jbc.M306097200 | 0.808 | |||
| 2002 | Paulussen A, Raes A, Matthijs G, Snyders DJ, Cohen N, Aerssens J. A novel mutation (T65P) in the PAS domain of the human potassium channel HERG results in the long QT syndrome by trafficking deficiency. The Journal of Biological Chemistry. 277: 48610-6. PMID 12354768 DOI: 10.1074/jbc.M206569200 | 0.468 | |||
| 2002 | Ottschytsch N, Raes A, Van Hoorick D, Snyders DJ. Obligatory heterotetramerization of three previously uncharacterized Kv channel α-subunits identified in the human genome Proceedings of the National Academy of Sciences of the United States of America. 99: 7986-7991. PMID 12060745 DOI: 10.1073/Pnas.122617999 | 0.78 | |||
| 1998 | Raes A, Vijver GVd, Goethals M, Bogaert Pv. Use‐dependent block of Ih in mouse dorsal root ganglion neurons by sinus node inhibitors British Journal of Pharmacology. 125: 741-750. PMID 9831910 DOI: 10.1038/Sj.Bjp.0702153 | 0.364 | |||
| 1998 | Kupershmidt S, Snyders DJ, Raes A, Roden DM. A K+ channel splice variant common in human heart lacks a C-terminal domain required for expression of rapidly activating delayed rectifier current. The Journal of Biological Chemistry. 273: 27231-5. PMID 9765245 DOI: 10.1074/Jbc.273.42.27231 | 0.438 | |||
| 1997 | Raes A, Wang Z, van den Berg RJ, Goethals M, Van de Vijver G, van Bogaert PP. Effect of cAMP and ATP on the hyperpolarization-activated current in mouse dorsal root ganglion neurons. Pflã¼Gers Archiv : European Journal of Physiology. 434: 543-50. PMID 9242717 DOI: 10.1007/S004240050434 | 0.349 | |||
| 1993 | Goethals M, Raes A, Bogaert PPv. Use-dependent block of the pacemaker current I(f) in rabbit sinoatrial node cells by zatebradine (UL-FS 49). On the mode of action of sinus node inhibitors. Circulation. 88: 2389-2401. PMID 8222132 DOI: 10.1161/01.Cir.88.5.2389 | 0.304 | |||
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