Christopher D. Spilling - Publications

Affiliations: 
1989- Chemistry University of Missouri - Saint Louis 
Area:
Organic Chemistry, Physical Chemistry, Biochemistry
Website:
https://www.umsl.edu/chemistry/Faculty/spilling.html

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Paudel RR, Ridenour JN, Rath NP, Spilling CD. Synthesis of Phosphonomethyl Tetrahydrofurans via the Mori-Tamaru Reaction of Phosphonodienes. Organic Letters. 22: 3830-3834. PMID 32330059 DOI: 10.1021/acs.orglett.0c01080  1
2019 Madani A, Ridenour JN, Martin BP, Paudel RR, Abdul Basir A, Le Moigne V, Herrmann JL, Audebert S, Camoin L, Kremer L, Spilling CD, Canaan S, Cavalier JF. Cyclipostins and Cyclophostin analogs are multi-target inhibitors that impair growth of Mycobacterium abscessus. Acs Infectious Diseases. PMID 31299146 DOI: 10.1021/acsinfecdis.9b00172  1
2019 Gnawali GR, Rath NP, Spilling CD. Synthesis of Phostones via the Palladium-Catalyzed Ring Opening of Epoxy vinyl phosphonates. The Journal of Organic Chemistry. PMID 31140269 DOI: 10.1021/acs.joc.9b00905  0.88
2017 Nguyen PC, Madani A, Santucci P, Martin BP, Paudel RR, Delattre S, Herrmann JL, Spilling CD, Kremer L, Canaan S, Cavalier JF. Cyclophostin and cyclipostins analogs, new promising molecules to treat mycobacterial-related diseases. International Journal of Antimicrobial Agents. PMID 29241819 DOI: 10.1016/j.ijantimicag.2017.12.001  0.32
2017 Nguyen PC, Delorme V, Bénarouche A, Martin BP, Paudel R, Gnawali GR, Madani A, Puppo R, Landry V, Kremer L, Brodin P, Spilling CD, Cavalier JF, Canaan S. Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis. Scientific Reports. 7: 11751. PMID 28924204 DOI: 10.1038/s41598-017-11843-4  0.32
2016 Hamper BC, Mannino MP, Mueller ME, Harrison LT, Spilling CD. Enantioseparation of α-Hydroxyallylphosphonates and Phosphonoallylic Carbonate Derivatives on Chiral Stationary Phases Using Sequential UV, Polarimetric, and Refractive Index Detection. Chirality. PMID 27516372 DOI: 10.1002/chir.22627  0.6
2015 Martin BP, Vasilieva E, Dupureur CM, Spilling CD. Synthesis and comparison of the biological activity of monocyclic phosphonate, difluorophosphonate and phosphate analogs of the natural AChE inhibitor cyclophostin. Bioorganic & Medicinal Chemistry. PMID 26585276 DOI: 10.1016/j.bmc.2015.10.044  1
2015 Sutivisedsak N, Dawadi S, Spilling CD. Trapping Hemiacetals with Phosphono Substituted Palladium π-Allyl Complexes for the Synthesis of Substituted Cyclic Ethers. Tetrahedron Letters. 56: 3534-3537. PMID 26236053 DOI: 10.1016/j.tetlet.2015.01.050  0.96
2015 Vasilieva E, Dutta S, Malla RK, Martin BP, Spilling CD, Dupureur CM. Rat hormone sensitive lipase inhibition by cyclipostins and their analogs. Bioorganic & Medicinal Chemistry. 23: 944-52. PMID 25678014 DOI: 10.1016/j.bmc.2015.01.028  1
2015 Spilling CD, Malla RK. Synthesis of non-racemic α-hydroxyphosphonates via asymmetric phospho-aldol reaction. Topics in Current Chemistry. 361: 83-136. PMID 25467537 DOI: 10.1007/128_2014_583  1
2015 Roy S, Sutivisedsak N, Hamper BC, Lyss AM, Spilling CD. A Practical and Scalable Synthesis of (S)- and (R)-1-(Dimethoxyphosphoryl)allyl Methyl Carbonates Synthesis (Germany). 47: 3669-3672. DOI: 10.1055/s-0035-1560487  1
2014 Paudyal MP, Wu L, Zhang ZY, Spilling CD, Wong CF. A new class of salicylic acid derivatives for inhibiting YopH of Yersinia pestis. Bioorganic & Medicinal Chemistry. 22: 6781-8. PMID 25468042 DOI: 10.1016/j.bmc.2014.10.042  1
2014 Malla RK, Ridenour JN, Spilling CD. Relay cross metathesis reactions of vinylphosphonates. Beilstein Journal of Organic Chemistry. 10: 1933-41. PMID 25246952 DOI: 10.3762/bjoc.10.201  1
2014 Regalado EL, Kozlowski MC, Curto JM, Ritter T, Campbell MG, Mazzotti AR, Hamper BC, Spilling CD, Mannino MP, Wan L, Yu JQ, Liu J, Welch CJ. Support of academic synthetic chemistry using separation technologies from the pharmaceutical industry. Organic & Biomolecular Chemistry. 12: 2161-6. PMID 24589831 DOI: 10.1039/c3ob42195c  1
2014 Sutivisedsak N, Dawadi S, Spilling CD. Trapping hemiacetals with phosphono substituted palladium π-allyl complexes for the synthesis of substituted cyclic ethers Tetrahedron Letters. DOI: 10.1016/j.tetlet.2015.01.050  1
2013 Point V, Malla RK, Carrière F, Canaan S, Spilling CD, Cavalier JF. Enantioselective inhibition of microbial lipolytic enzymes by nonracemic monocyclic enolphosphonate analogues of cyclophostin. Journal of Medicinal Chemistry. 56: 4393-401. PMID 23651298 DOI: 10.1021/jm4000787  1
2012 Point V, Malla RK, Diomande S, Martin BP, Delorme V, Carriere F, Canaan S, Rath NP, Spilling CD, Cavalier JF. Synthesis and kinetic evaluation of cyclophostin and cyclipostins phosphonate analogs as selective and potent inhibitors of microbial lipases. Journal of Medicinal Chemistry. 55: 10204-19. PMID 23095026 DOI: 10.1021/jm301216x  1
2012 Kottakota SK, Evangelopoulos D, Alnimr A, Bhakta S, McHugh TD, Gray M, Groundwater PW, Marrs EC, Perry JD, Spilling CD, Harburn JJ. Synthesis and biological evaluation of purpurealidin E-derived marine sponge metabolites: aplysamine-2, aplyzanzine A, and suberedamines A and B. Journal of Natural Products. 75: 1090-101. PMID 22620987 DOI: 10.1021/np300102z  1
2012 Roy S, Spilling CD. An expeditious total synthesis of both diastereoisomeric lipid dihydroxytetrahydrofurans from Notheia anomala. Organic Letters. 14: 2230-3. PMID 22506757 DOI: 10.1021/ol300597u  1
2011 Malla RK, Bandyopadhyay S, Spilling CD, Dutta S, Dupureur CM. The first total synthesis of (±)-cyclophostin and (±)-cyclipostin P: inhibitors of the serine hydrolases acetyl cholinesterase and hormone sensitive lipase. Organic Letters. 13: 3094-7. PMID 21591624 DOI: 10.1021/ol200991x  1
2011 Mydock LK, Spilling CD, Demchenko AV. Concise synthesis of 1,3-di-O-substituted tetrahydropyran derivatives as conformationally stable pyranose mimetics Comptes Rendus Chimie. 14: 301-306. DOI: 10.1016/j.crci.2010.05.016  1
2010 Roy S, Spilling CD. Synthesis of the C(18)-C(34) fragment of amphidinolide C and the C(18)-C(29) fragment of amphidinolide F. Organic Letters. 12: 5326-9. PMID 21028791 DOI: 10.1021/ol102345v  1
2010 Paudyal MP, Rath NP, Spilling CD. A formal synthesis of the C1-C9 fragment of amphidinolide C employing the Tamaru reaction. Organic Letters. 12: 2954-7. PMID 20527780 DOI: 10.1021/ol100959a  0.88
2010 Dutta S, Malla RK, Bandyopadhyay S, Spilling CD, Dupureur CM. Synthesis and kinetic analysis of some phosphonate analogs of cyclophostin as inhibitors of human acetylcholinesterase. Bioorganic & Medicinal Chemistry. 18: 2265-74. PMID 20189400 DOI: 10.1016/j.bmc.2010.01.063  1
2009 He A, Sutivisedsak N, Spilling CD. Stereoselective synthesis of cyclic ethers via the palladium-catalyzed intramolecular addition of alcohols to phosphono allylic carbonates. Organic Letters. 11: 3124-7. PMID 19586068 DOI: 10.1021/ol900980s  1
2009 Ley SV, Tackett MN, Maddess ML, Anderson JC, Brennan PE, Cappi MW, Heer JP, Helgen C, Kori M, Kouklovsky C, Marsden SP, Norman J, Osborn DP, Palomero MA, Pavey JB, ... ... Spilling CD, et al. Total synthesis of rapamycin. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 2874-914. PMID 19204960 DOI: 10.1002/chem.200801656  1
2008 Bandyopadhyay S, Dutta S, Spilling CD, Dupureur CM, Rath NP. Synthesis and biological evaluation of a phosphonate analog of the natural acetyl cholinesterase inhibitor cyclophostin. The Journal of Organic Chemistry. 73: 8386-91. PMID 18821801 DOI: 10.1021/jo801453v  1
2008 Ley SV, Abad-Somovilla A, Anderson JC, Ayats C, Bänteli R, Beckmann E, Boyer A, Brasca MG, Brice A, Broughton HB, Burke BJ, Cleator E, Craig D, Denholm AA, Denton RM, ... ... Spilling CD, et al. The synthesis of azadirachtin: a potent insect antifeedant. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 10683-704. PMID 18821532 DOI: 10.1002/chem.200801103  1
2008 Yan B, Spilling CD. Synthesis of cyclopentenones via intramolecular HWE and the palladium-catalyzed reactions of allylic hydroxy phosphonate derivatives. The Journal of Organic Chemistry. 73: 5385-96. PMID 18557652 DOI: 10.1021/jo8004028  1
2007 Badkar PA, Rath NP, Spilling CD. Asymmetric synthesis of 2-alkyl-3-phosphonopropanoic acids via P-C bond formation and hydrogenation. Organic Letters. 9: 3619-22. PMID 17691799 DOI: 10.1021/ol701500s  0.88
2007 Maddess ML, Tackett MN, Watanabe H, Brennan PE, Spilling CD, Scott JS, Osborn DP, Ley SV. Total synthesis of rapamycin. Angewandte Chemie (International Ed. in English). 46: 591-7. PMID 17154218 DOI: 10.1002/anie.200604053  1
2005 Harburn JJ, Rath NP, Spilling CD. Efficient synthesis of tyrosine-derived marine sponge metabolites via acylation of amines with a coumarin. The Journal of Organic Chemistry. 70: 6398-403. PMID 16050702 DOI: 10.1021/jo050846r  0.88
2004 He A, Yan B, Thanavaro A, Spilling CD, Rath NP. Synthesis of nonracemic allylic hydroxy phosphonates via alkene cross metathesis. The Journal of Organic Chemistry. 69: 8643-51. PMID 15575740 DOI: 10.1021/jo0490090  1
2004 Yan B, Spilling CD. Stereospecific Pd(O)-catalyzed malonate additions to allylic hydroxy phosphonate derivatives: a formal synthesis of (-)-enterolactone. The Journal of Organic Chemistry. 69: 2859-62. PMID 15074940 DOI: 10.1021/jo035795h  1
1998 Xu Z, Dong Y, Spilling CD, Lakshminarayanan V, Pappu SV. Intermolecular charge transfer in organic donor-acceptor systems for optical storage applications Proceedings of Spie - the International Society For Optical Engineering. 3417: 12-18. DOI: 10.1117/12.323488  1
1998 De La Cruz A, Koeller KJ, Rath NP, Spilling CD, Vasconcelos ICF. The synthesis, structure and properties of diazaphospholes: Reagents and ligands for asymmetric synthesis Tetrahedron. 54: 10513-10524. DOI: 10.1016/S0040-4020(98)00502-X  1
1995 Blazis VJ, Koeller KJ, Spilling CD. Reactions of chiral phosphorous acid diamides: The asymmetric synthesis of chiral α-hydroxy phosphonamides, phosphonates, and phosphonic acids The Journal of Organic Chemistry. 60: 931-940. DOI: 10.1080/10426509308037389  1
1994 Rath NP, Spilling CD. The enantioselective addition of dialkylphosphites to aldehydes: Catalysis by a lanthanum binaphthoxide complex Tetrahedron Letters. 35: 227-230. DOI: 10.1016/S0040-4039(00)76517-8  1
1994 Blazis VJ, Koeller KJ, Spilling CD. Asymmetric synthesis of α-hydroxy- phosphonamides, phosphonates and phosphonic acids Tetrahedron: Asymmetry. 5: 499-502. DOI: 10.1016/0957-4166(94)80002-2  1
1991 Koeller KJ, Spilling CD. The preparation and reactions of chiral phosphorous acid diamides Tetrahedron Letters. 32: 6297-6300. DOI: 10.1016/0040-4039(91)80151-U  1
1989 Barrett AGM, Cheng MC, Sakdarat S, Spilling CD, Taylor SJ. Stereocontrolled total synthesis of the penicillanate ester (2S,5R)-benzyl 3,3-dimethyl-7-oxo-4-thia-1-azabicyclo [3.2.0] heptane-2-carboxylate Tetrahedron Letters. 30: 2349-2350. DOI: 10.1016/S0040-4039(01)80395-6  1
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