| Year |
Citation |
Score |
| 2018 |
Manouchehri J, Kalafatis M. Abstract 1863: Ursolic acid sensitizes rhTRAIL-resistant triple negative breast carcinoma to rhTRAIL-induced apoptosis Cancer Research. 78: 1863-1863. DOI: 10.1158/1538-7445.Am2018-1863 |
0.309 |
|
| 2017 |
Hirbawi J, Kalafatis M. Spellbinding Effects of the Acidic COOH-Terminus of Factor Va Heavy Chain on Prothrombinase Activity and Function. Acs Omega. 2: 5529-5537. PMID 29250609 DOI: 10.1021/acsomega.7b00769 |
0.506 |
|
| 2016 |
Wiencek JR, Hirbawi J, Yee VC, Kalafatis M. The Dual Regulatory Role of Amino Acids Leu480 and Gln481 of Prothrombin. The Journal of Biological Chemistry. 291: 1565-81. PMID 26601957 DOI: 10.1074/Jbc.M115.691956 |
0.567 |
|
| 2015 |
Turner KA, Lindner D, Kalafatis M. Abstract B34: Sensitization of TRAIL-resistant malignant melanomas by ellagic acid Cancer Research. 75. DOI: 10.1158/1538-7445.Mel2014-B34 |
0.337 |
|
| 2014 |
Turner K, Lindner D, Kalafatis M. Abstract 2289: Effects of TRAIL and ellagic acid on malignant melanoma A375 in vitro and in vivo Cancer Research. 74: 2289-2289. DOI: 10.1158/1538-7445.Am2014-2289 |
0.332 |
|
| 2013 |
Wiencek JR, Na M, Hirbawi J, Kalafatis M. Amino acid region 1000-1008 of factor V is a dynamic regulator for the emergence of procoagulant activity. The Journal of Biological Chemistry. 288: 37026-38. PMID 24178294 DOI: 10.1074/Jbc.M113.462374 |
0.524 |
|
| 2013 |
Wiencek JR, Kalafatis M. The Regulatory Function Of Amino Acid Region 473-487 Of Prothrombin During Coagulation Blood. 122: 3574-3574. DOI: 10.1182/Blood.V122.21.3574.3574 |
0.593 |
|
| 2012 |
Mohammad HF, Lindner DJ, Kalafatis M. Abstract 1933: Ellagic acid induces apoptosis and cell cycle arrest in HeLa cells and inhibits HPV oncogene expression Cancer Research. 72: 1933-1933. DOI: 10.1158/1538-7445.Am2012-1933 |
0.785 |
|
| 2011 |
Barhoover MA, Kalafatis M. Cleavage at both Arg306 and Arg506 is required and sufficient for timely and efficient inactivation of factor Va by activated protein C. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. 22: 317-24. PMID 21467919 DOI: 10.1097/Mbc.0B013E3283456C4E |
0.851 |
|
| 2011 |
Na M, Wiencek JR, Hirbawi J, Kalafatis M. Cleavage At Arg1018 During Thrombin-Mediated Activation of Coagulation Factor V Is Dispensable Blood. 118: 1186-1186. DOI: 10.1182/Blood.V118.21.1186.1186 |
0.563 |
|
| 2010 |
Hirbawi J, Vaughn JL, Bukys MA, Vos HL, Kalafatis M. Contribution of amino acid region 659-663 of Factor Va heavy chain to the activity of factor Xa within prothrombinase . Biochemistry. 49: 8520-34. PMID 20722419 DOI: 10.1021/Bi101097T |
0.833 |
|
| 2010 |
Wiencek JR, Hirbawi J, Na M, Kalafatis M. Amino Acid Region 1000–1008 of Coagulation Factor V Is a Dynamic Regulator for the Emergence of Procoagulant Activity Blood. 116: 2221-2221. DOI: 10.1182/Blood.V116.21.2221.2221 |
0.566 |
|
| 2010 |
Hirbawi J, Kim PY, Nesheim ME, Kalafatis M. The Role of Amino Acids 700–701 of the Factor Va Heavy Chain During Prothrombin Activation by Factor Xa Blood. 116: 2203-2203. DOI: 10.1182/Blood.V116.21.2203.2203 |
0.602 |
|
| 2010 |
Vaughn JL, Hirbawi J, Bukys MA, Kalafatis M. Role of the N-Terminal Amino Acid Region of Factor Va Light Chain In Prothrombinase Assembly and Function. Blood. 116: 1127-1127. DOI: 10.1182/Blood.V116.21.1127.1127 |
0.814 |
|
| 2009 |
Mohammad H, Lindner Dj, Kalafatis M. Casein Kinase CK2 Inhibition Results in Tumor Suppression. Blood. 114: 5052-5052. DOI: 10.1182/Blood.V114.22.5052.5052 |
0.757 |
|
| 2009 |
Hirbawi J, Kalafatis M. Amino Acids Asp695 and Tyr696 of Factor Va Are Essential for Optimal Rate of Prothrombin Activation by Prothrombinase. Blood. 114: 3163-3163. DOI: 10.1182/Blood.V114.22.3163.3163 |
0.623 |
|
| 2009 |
Hirbawi J, Kalafatis M. The Role of Amino Acids 659-663 of Factor Va Heavy Chain During Prothrombin Activation by Prothrombinase. Blood. 114: 2131-2131. DOI: 10.1182/Blood.V114.22.2131.2131 |
0.614 |
|
| 2009 |
Barhoover MA, Kalafatis M. Clevage at Both Arg306 and Arg506 Are Required for Timely and Efficient Inactivation of Factor Va by Activated Protein C: Influence of the Assay. Blood. 114: 2121-2121. DOI: 10.1182/Blood.V114.22.2121.2121 |
0.849 |
|
| 2008 |
Barhoover MA, Orban T, Bukys MA, Kalafatis M. Cooperative regulation of the activity of factor Xa within prothrombinase by discrete amino acid regions from factor Va heavy chain. Biochemistry. 47: 12835-43. PMID 18991406 DOI: 10.1021/Bi801241R |
0.825 |
|
| 2008 |
Hirbawi J, Bukys MA, Barhoover MA, Erdogan E, Kalafatis M. Role of the acidic hirudin-like COOH-terminal amino acid region of factor Va heavy chain in the enhanced function of prothrombinase. Biochemistry. 47: 7963-74. PMID 18590276 DOI: 10.1021/Bi800593K |
0.842 |
|
| 2008 |
Barhoover MA, Orban T, Beck DO, Bukys MA, Kalafatis M. Contribution of amino acid region 334-335 from factor Va heavy chain to the catalytic efficiency of prothrombinase. Biochemistry. 47: 6840-50. PMID 18537263 DOI: 10.1021/Bi800057R |
0.824 |
|
| 2008 |
Bukys MA, Orban T, Kim PY, Nesheim ME, Kalafatis M. The interaction of fragment 1 of prothrombin with the membrane surface is a prerequisite for optimum expression of factor Va cofactor activity within prothrombinase. Thrombosis and Haemostasis. 99: 511-22. PMID 18327399 DOI: 10.1160/Th07-08-0532 |
0.831 |
|
| 2008 |
Erdogan E, Bukys MA, Kalafatis M. The contribution of amino acid residues 1508-1515 of factor V to light chain generation. Journal of Thrombosis and Haemostasis : Jth. 6: 118-24. PMID 17944989 DOI: 10.1111/J.1538-7836.2007.02803.X |
0.834 |
|
| 2008 |
Hirbawi J, Kalafatis M. The Regulatory Function of Amino Acid Region 659–663 of Factor Va on Prothrombinase during Thrombin Formation. Blood. 112: 2012-2012. DOI: 10.1182/Blood.V112.11.2012.2012 |
0.604 |
|
| 2008 |
Kalafatis M, Hirbawi J, Barhoover MA, Bukys MA. The Effect of Factor Va on Prothrombinase Function Blood. 112: 1020-1020. DOI: 10.1182/Blood.V112.11.1020.1020 |
0.826 |
|
| 2007 |
Erdogan E, Bukys MA, Orfeo T, Mann KG, Kalafatis M. Identification of an inactivating cleavage site for alpha-thrombin on the heavy chain of factor Va. Thrombosis and Haemostasis. 98: 998-1006. PMID 18000604 DOI: 10.1160/Th07-06-0431 |
0.808 |
|
| 2007 |
Bukys MA, Orban T, Kim PY, Nesheim ME, Kalafatis M. Factor Va Cofactor Activity Is Dependent on the Interaction of Prothrombin with the Membrane Surface. Blood. 110: 2702-2702. DOI: 10.1182/Blood.V110.11.2702.2702 |
0.833 |
|
| 2007 |
Kalafatis M, Bukys MA, Hirbawi J, Kim PY, Barhoover MA, Nesheim ME. Understanding the Factor Va Cofactor Effect within Prothrombinase. Blood. 110: 2700-2700. DOI: 10.1182/Blood.V110.11.2700.2700 |
0.821 |
|
| 2007 |
Hirbawi J, Bukys MA, Barhoover MA, Kalafatis M. The Acidic COOH-Terminal Region of Factor Va Heavy Chain Controls the Rate of Prothrombin Activation by Prothrombinase. Blood. 110: 1745-1745. DOI: 10.1182/Blood.V110.11.1745.1745 |
0.844 |
|
| 2006 |
Butenas S, Orfeo T, Kalafatis M, Mann KG. Peptidomimetic inhibitors for activated protein C: implications for hemophilia management. Journal of Thrombosis and Haemostasis : Jth. 4: 2411-6. PMID 17059471 DOI: 10.1111/J.1538-7836.2006.02226.X |
0.436 |
|
| 2006 |
Bukys MA, Kim PY, Nesheim ME, Kalafatis M. A control switch for prothrombinase: characterization of a hirudin-like pentapeptide from the COOH terminus of factor Va heavy chain that regulates the rate and pathway for prothrombin activation. The Journal of Biological Chemistry. 281: 39194-204. PMID 17020886 DOI: 10.1074/Jbc.M604482200 |
0.807 |
|
| 2006 |
Bukys MA, Orban T, Kim PY, Beck DO, Nesheim ME, Kalafatis M. The structural integrity of anion binding exosite I of thrombin is required and sufficient for timely cleavage and activation of factor V and factor VIII. The Journal of Biological Chemistry. 281: 18569-80. PMID 16624813 DOI: 10.1074/Jbc.M600752200 |
0.829 |
|
| 2006 |
Bukys MA, Simioni P, Smith K, Spiezia L, Kalafatis M. Isolation and Characterization of an Antifactor VIII Antibody from a Patient with Acquired Hemophilia A and a Severe Hemorrhagic Syndrome. Blood. 108: 4073-4073. DOI: 10.1182/Blood.V108.11.4073.4073 |
0.744 |
|
| 2006 |
Erdogan E, Bukys MA, Orfeo T, Mann KG, Kalafatis M. Cleavage of Factor Va Heavy Chain at Arg643 by Thrombin Partially Inactivates the Cofactor. Blood. 108: 1703-1703. DOI: 10.1182/Blood.V108.11.1703.1703 |
0.864 |
|
| 2006 |
Orban T, Kalafatis M. Human Coagulation Factor Va Interaction with Phospholipid Vesicles: A Molecular Dynamics Study. Blood. 108: 1699-1699. DOI: 10.1182/Blood.V108.11.1699.1699 |
0.715 |
|
| 2006 |
Bukys MA, Kim PY, Nesheim ME, Kalafatis M. Controlling the Pathway for Prothrombin Activation by Prothrombinase. Blood. 108: 1695-1695. DOI: 10.1182/Blood.V108.11.1695.1695 |
0.825 |
|
| 2006 |
Ciocea A, Byzova TV, Kalafatis M. Role of Casein Kinase 2 in Platelets Release from Megakaryocytes. Blood. 108: 1534-1534. DOI: 10.1182/Blood.V108.11.1534.1534 |
0.777 |
|
| 2005 |
Orban T, Kalafatis M, Gogonea V. Completed three-dimensional model of human coagulation factor va. Molecular dynamics simulations and structural analyses. Biochemistry. 44: 13082-90. PMID 16185076 DOI: 10.1021/Bi050891T |
0.665 |
|
| 2005 |
Bukys MA, Blum MA, Kim PY, Brufatto N, Nesheim ME, Kalafatis M. Incorporation of factor Va into prothrombinase is required for coordinated cleavage of prothrombin by factor Xa. The Journal of Biological Chemistry. 280: 27393-401. PMID 15897196 DOI: 10.1074/Jbc.M503435200 |
0.812 |
|
| 2005 |
Gould WR, Simioni P, Silveira JR, Tormene D, Kalafatis M, Tracy PB. Megakaryocytes endocytose and subsequently modify human factor V in vivo to form the entire pool of a unique platelet-derived cofactor. Journal of Thrombosis and Haemostasis : Jth. 3: 450-6. PMID 15748232 DOI: 10.1111/J.1538-7836.2005.01157.X |
0.382 |
|
| 2005 |
Kalafatis M. Coagulation factor V: a plethora of anticoagulant molecules. Current Opinion in Hematology. 12: 141-8. PMID 15725905 DOI: 10.1097/01.Moh.0000155016.30296.90 |
0.584 |
|
| 2005 |
Ciocea A, Narizhneva NV, Erdogan E, Byzova TV, Kalafatis M. Casein Kinase II Inhibition in MEG-01 Cell Line Results in Apoptosis, Megakaryocytopoiesis and Functional Platelets Release. Blood. 106: 4328-4328. DOI: 10.1182/Blood.V106.11.4328.4328 |
0.655 |
|
| 2005 |
Orban T, Kalafatis M. Human Prothrombin Fragment 1 Conformational Changes Following Binding to Phospholipid Vesicles: A Computational Study. Blood. 106: 4047-4047. DOI: 10.1182/Blood.V106.11.4047.4047 |
0.649 |
|
| 2005 |
Kalafatis M, Chiott RE, Branda RF, Mann KG. Activated Protein C-Resistance Induced by a Low Molecular Weight Inhibitor. Blood. 106: 2136-2136. DOI: 10.1182/Blood.V106.11.2136.2136 |
0.457 |
|
| 2005 |
Bukys MA, Orban T, Kim PY, Nesheim ME, Kalafatis M. Exposure of Anion Binding Exosite I of Thrombin Is Required and Sufficient for Timely Cleavage and Activation of Factor V and Factor VIII. Blood. 106: 1951-1951. DOI: 10.1182/Blood.V106.11.1951.1951 |
0.826 |
|
| 2005 |
Blum MA, Orban T, Beck DO, Kalafatis M. The Specific Contribution of Amino Acids 334 and 335 from Factor Va Heavy Chain to the Catalytic Efficiency of Prothrombinase. Blood. 106: 1027-1027. DOI: 10.1182/Blood.V106.11.1027.1027 |
0.762 |
|
| 2005 |
Hirbawi J, Blum MA, Bukys MA, Orban T, Kalafatis M. Evidence That the COOH-Terminal Region of Factor Va Heavy Chain Is Involved in the Regulation of Prothrombinase Activity. Blood. 106: 1025-1025. DOI: 10.1182/Blood.V106.11.1025.1025 |
0.837 |
|
| 2004 |
Beck DO, Bukys MA, Singh LS, Szabo KA, Kalafatis M. The contribution of amino acid region ASP695-TYR698 of factor V to procofactor activation and factor Va function. The Journal of Biological Chemistry. 279: 3084-95. PMID 14559913 DOI: 10.1074/Jbc.M306850200 |
0.825 |
|
| 2004 |
Blum MA, Beck DO, Kalafatis M. A Peptide Region from Factor Va Increases Factor Xa Efficiency for Cleavage of Prothrombin. Blood. 104: 3977-3977. DOI: 10.1182/Blood.V104.11.3977.3977 |
0.628 |
|
| 2004 |
Erdogan E, Kalafatis M. Identification of Sulfo-Tyrosines of Factor V. Blood. 104: 1731-1731. DOI: 10.1182/Blood.V104.11.1731.1731 |
0.795 |
|
| 2004 |
Bukys MA, Kim P, Blum MA, Nesheim ME, Kalafatis M. Cofactor Directed Catalysis. Blood. 104: 1715-1715. DOI: 10.1182/Blood.V104.11.1715.1715 |
0.798 |
|
| 2003 |
Kalafatis M, Beck DO, Mann KG. Structural requirements for expression of factor Va activity. The Journal of Biological Chemistry. 278: 33550-61. PMID 12788947 DOI: 10.1074/Jbc.M303153200 |
0.606 |
|
| 2003 |
Singh LS, Bukys MA, Beck DO, Kalafatis M. Amino acids Glu323, Tyr324, Glu330, and Val331 of factor Va heavy chain are essential for expression of cofactor activity. The Journal of Biological Chemistry. 278: 28335-45. PMID 12738785 DOI: 10.1074/Jbc.M300233200 |
0.816 |
|
| 2003 |
Mann KG, Kalafatis M. Factor V: a combination of Dr Jekyll and Mr Hyde. Blood. 101: 20-30. PMID 12393635 DOI: 10.1182/Blood-2002-01-0290 |
0.438 |
|
| 2002 |
Kalafatis M, Beck DO. Identification of a binding site for blood coagulation factor Xa on the heavy chain of factor Va. Amino acid residues 323-331 of factor V represent an interactive site for activated factor X. Biochemistry. 41: 12715-28. PMID 12379114 DOI: 10.1021/Bi026208+ |
0.588 |
|
| 2002 |
Singh LS, Kalafatis M. Sequencing of full-length cDNA encoding the alpha and beta subunits of human casein kinase II from human platelets and megakaryocytic cells. Expression of the casein kinase IIalpha intronless gene in a megakaryocytic cell line. Biochemistry. 41: 8935-40. PMID 12102635 DOI: 10.1021/Bi025791R |
0.338 |
|
| 2002 |
Kalafatis M, Simioni P, Tormene D, Beck DO, Luni S, Girolami A. Isolation and characterization of an antifactor V antibody causing activated protein C resistance from a patient with severe thrombotic manifestations. Blood. 99: 3985-92. PMID 12010798 DOI: 10.1182/Blood.V99.11.3985 |
0.488 |
|
| 2002 |
Hung K, Sun X, Ding H, Kalafatis M, Simioni P, Guo B. A matrix-assisted laser desorption/ionization time-of-flight based method for screening the 1691G --> A mutation in the factor V gene. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. 13: 117-22. PMID 11914653 DOI: 10.1097/00001721-200203000-00006 |
0.382 |
|
| 2002 |
Silveira JR, Kalafatis M, Tracy PB. Carbohydrate moieties on the procofactor factor V, but not the derived cofactor factor Va, regulate its inactivation by activated protein C. Biochemistry. 41: 1672-80. PMID 11814362 DOI: 10.1021/Bi011304G |
0.532 |
|
| 2002 |
Kalafatis M, Mann KG. Factor V: Dr. Jeckyll and Mr. Hyde. Advances in Experimental Medicine and Biology. 489: 31-43. PMID 11554589 DOI: 10.1007/978-1-4615-1277-6_3 |
0.56 |
|
| 2001 |
Kalafatis M, Simioni P, Bernardi F. Phenotype and genotype expression in pseudohomozygous R2 factor V. Blood. 98: 1988-9. PMID 11565539 DOI: 10.1182/Blood.V98.6.1988 |
0.502 |
|
| 2001 |
Kalafatis M, Mann KG. The role of the membrane in the inactivation of factor va by plasmin. Amino acid region 307-348 of factor V plays a critical role in factor Va cofactor function. The Journal of Biological Chemistry. 276: 18614-23. PMID 11278331 DOI: 10.1074/Jbc.M007134200 |
0.576 |
|
| 2001 |
Kalafatis M, Tormene D, Luni S, Zerbinati P, Barzon L, Palù G, Girolami A, Simioni P. Abnormal Propeptide Processing Resulting in the Presence of Two Abnormal Species of Protein C in Plasma Thrombosis and Haemostasis. 86: 1017-1022. DOI: 10.1055/S-0037-1616527 |
0.434 |
|
| 2000 |
Castoldi E, Simioni P, Kalafatis M, Lunghi B, Tormene D, Girelli D, Girolami A, Bernardi F. Combinations of 4 mutations (FV R506Q, FV H1299R, FV Y1702C, PT 20210G/A) affecting the prothrombinase complex in a thrombophilic family Blood. 96: 1443-1448. DOI: 10.1182/Blood.V96.4.1443.H8001443_1443_1448 |
0.327 |
|
| 1999 |
Hockin MF, Cawthern KM, Kalafatis M, Mann KG. A model describing the inactivation of factor Va by APC: bond cleavage, fragment dissociation, and product inhibition. Biochemistry. 38: 6918-34. PMID 10346914 DOI: 10.1021/Bi981966E |
0.515 |
|
| 1999 |
Kalafatis M, Bernardi F, Simioni P, Lunghi B, Girolami A, Mann KG. Phenotype and genotype expression in pseudohomozygous factor VLEIDEN : the need for phenotype analysis. Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 336-42. PMID 9974416 DOI: 10.1161/01.Atv.19.2.336 |
0.481 |
|
| 1999 |
Simioni P, Kalafatis M, Manfrin D, Tormene D, Girolami A. Factor V variants, activated protein C resistance and venous thromboembolism. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. 9: 661-2. PMID 9863717 DOI: 10.1097/00001721-199810000-00015 |
0.389 |
|
| 1998 |
Camire RM, Kalafatis M, Tracy PB. Proteolysis of factor V by cathepsin G and elastase indicates that cleavage at Arg1545 optimizes cofactor function by facilitating factor Xa binding. Biochemistry. 37: 11896-906. PMID 9718313 DOI: 10.1021/Bi980520V |
0.564 |
|
| 1998 |
Long GL, Lu D, Xie RL, Kalafatis M. Human protein S cleavage and inactivation by coagulation factor Xa. The Journal of Biological Chemistry. 273: 11521-6. PMID 9565566 DOI: 10.1074/Jbc.273.19.11521 |
0.556 |
|
| 1998 |
Kalafatis M. Identification and partial characterization of factor Va heavy chain kinase from human platelets. The Journal of Biological Chemistry. 273: 8459-66. PMID 9525959 DOI: 10.1074/Jbc.273.14.8459 |
0.482 |
|
| 1998 |
Hockin MF, Kalafatis M, Shatos M, Mann KG. Protein C activation and factor Va inactivation on human umbilical vein endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 2765-75. PMID 9409254 DOI: 10.1161/01.Atv.17.11.2765 |
0.483 |
|
| 1998 |
Kalafatis M, Egan JO, van 't Veer C, Cawthern KM, Mann KG. The regulation of clotting factors. Critical Reviews in Eukaryotic Gene Expression. 7: 241-80. PMID 9399073 DOI: 10.1615/Critreveukargeneexpr.V7.I3.40 |
0.551 |
|
| 1998 |
Egan JO, Kalafatis M, Mann KG. The effect of Arg306-->Ala and Arg506-->Gln substitutions in the inactivation of recombinant human factor Va by activated protein C and protein S. Protein Science : a Publication of the Protein Society. 6: 2016-27. PMID 9300501 DOI: 10.1002/Pro.5560060922 |
0.556 |
|
| 1998 |
Camire RM, Kalafatis M, Simioni P, Girolami A, Tracy PB. Platelet-Derived Factor Va/VaLeiden Cofactor Activities Are Sustained on the Surface of Activated Platelets Despite the Presence of Activated Protein C Blood. 91: 2818-2829. DOI: 10.1182/Blood.V91.8.2818.2818_2818_2829 |
0.468 |
|
| 1998 |
Castoldi E, Kalafatis M, Lunghi B, Simioni P, Ioannou P, Petio M, Girolami A, Mann K, Bernardi F. Molecular Bases of Pseudo-homozygous APC Resistance: The Compound Heterozygosity for FV R506Q and a FV Null Mutation Results in the Exclusive Presence of FV Leiden Molecules in Plasma Thrombosis and Haemostasis. 80: 403-406. DOI: 10.1055/S-0037-1615220 |
0.302 |
|
| 1997 |
Van 'T Veer C, Golden NJ, Kalafatis M, Simioni P, Bertina RM, Mann KG. An in vitro analysis of the combination of hemophilia A and factor V(LEIDEN) Blood. 90: 3067-3072. PMID 9376587 DOI: 10.1182/Blood.V90.8.3067 |
0.483 |
|
| 1997 |
Van 't Veer C, Kalafatis M, Bertina RM, Simioni P, Mann KG. Increased tissue factor-initiated prothrombin activation as a result of the Arg506 → Gln mutation in factor V(LEIDEN) Journal of Biological Chemistry. 272: 20721-20729. PMID 9252393 DOI: 10.1074/Jbc.272.33.20721 |
0.483 |
|
| 1997 |
Mann KG, Hockin MF, Begin KJ, Kalafatis M. Activated protein C cleavage of factor Va leads to dissociation of the A2 domain. The Journal of Biological Chemistry. 272: 20678-83. PMID 9252387 DOI: 10.1074/Jbc.272.33.20678 |
0.475 |
|
| 1997 |
Kalafatis M, Mann KG. Factor VLeiden and thrombophilia. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 620-7. PMID 9108773 DOI: 10.1161/01.Atv.17.4.620 |
0.557 |
|
| 1997 |
van 't Veer C, Golden NJ, Kalafatis M, Mann KG. Inhibitory mechanism of the protein C pathway on tissue factor-induced thrombin generation. Synergistic effect in combination with tissue factor pathway inhibitor. The Journal of Biological Chemistry. 272: 7983-94. PMID 9065469 DOI: 10.1074/Jbc.272.12.7983 |
0.498 |
|
| 1997 |
Butenas S, Kalafatis M, Mann KG. Analysis of tissue plasminogen activator specificity using peptidyl fluorogenic substrates. Biochemistry. 36: 2123-31. PMID 9047311 DOI: 10.1021/Bi9617670 |
0.44 |
|
| 1996 |
Kalafatis M, Egan JO, van't Veer C, Mann KG. Regulation and regulatory role of gamma-carboxyglutamic acid containing clotting factors. Critical Reviews in Eukaryotic Gene Expression. 6: 87-101. PMID 8882309 DOI: 10.1615/Critreveukargeneexpr.V6.I1.60 |
0.454 |
|
| 1996 |
Bajzar L, Kalafatis M, Simioni P, Tracy PB. An antifibrinolytic mechanism describing the prothrombotic effect associated with factor VLeiden. The Journal of Biological Chemistry. 271: 22949-52. PMID 8798478 DOI: 10.1074/Jbc.271.38.22949 |
0.56 |
|
| 1996 |
Kalafatis M, Haley PE, Lu D, Bertina RM, Long GL, Mann KG. Proteolytic events that regulate factor V activity in whole plasma from normal and activated protein C (APC)-resistant individuals during clotting: an insight into the APC-resistance assay. Blood. 87: 4695-707. PMID 8639839 DOI: 10.1182/Blood.V87.11.4695.Bloodjournal87114695 |
0.538 |
|
| 1996 |
Simioni P, Kalafatis M, Millar D, Henderson S, Luni S, Cooper D, Girolami A. Compound heterozygous protein C deficiency resulting in the presence of only the beta-form of protein C in plasma Blood. 88: 2101-2108. DOI: 10.1182/Blood.V88.6.2101.Bloodjournal8862101 |
0.389 |
|
| 1996 |
Lu D, Kalafatis M, Mann K, Long G. Comparison of activated protein C/protein S-mediated inactivation of human factor VIII and factor V Blood. 87: 4708-4717. DOI: 10.1182/Blood.V87.11.4708.Bloodjournal87114708 |
0.457 |
|
| 1995 |
Kalafatis M, Bertina RM, Rand MD, Mann KG. Characterization of the molecular defect in factor VR506Q. The Journal of Biological Chemistry. 270: 4053-7. PMID 7876154 DOI: 10.1074/Jbc.270.8.4053 |
0.545 |
|
| 1995 |
Camire RM, Kalafatis M, Cushman M, Tracy RP, Mann KG, Tracy PB. The mechanism of inactivation of human platelet factor Va from normal and activated protein C-resistant individuals. The Journal of Biological Chemistry. 270: 20794-800. PMID 7657663 DOI: 10.1074/Jbc.270.35.20794 |
0.582 |
|
| 1995 |
Kalafatis M, Lu D, Bertina RM, Long GL, Mann KG. Biochemical prototype for familial thrombosis. A study combining a functional protein C mutation and factor V Leiden. Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 2181-7. PMID 7489240 DOI: 10.1161/01.Atv.15.12.2181 |
0.481 |
|
| 1994 |
Kalafatis M, Rand MD, Mann KG. Factor Va-membrane interaction is mediated by two regions located on the light chain of the cofactor. Biochemistry. 33: 486-93. PMID 8286378 DOI: 10.1021/Bi00168A013 |
0.384 |
|
| 1994 |
Kalafatis M, Xue J, Lawler CM, Mann KG. Contribution of the heavy and light chains of factor Va to the interaction with factor Xa Biochemistry®. 6538-6545. PMID 8204589 DOI: 10.1021/Bi00187A022 |
0.526 |
|
| 1994 |
Butenas S, Lawson JH, Kalafatis M, Mann KG. Cooperative interaction of divalent metal ions, substrate, and tissue factor with factor VIIa. Biochemistry. 33: 3449-56. PMID 8136382 DOI: 10.1021/Bi00177A039 |
0.501 |
|
| 1994 |
Kalafatis M, Swords NA, Rand MD, Mann KG. Membrane-dependent reactions in blood coagulation: role of the vitamin K-dependent enzyme complexes. Biochimica Et Biophysica Acta. 1227: 113-29. PMID 7986819 DOI: 10.1016/0925-4439(94)90086-8 |
0.304 |
|
| 1994 |
Lu D, Kalafatis M, Mann K, Long G. Loss of membrane-dependent factor Va cleavage: a mechanistic interpretation of the pathology of protein CVermont Blood. 84: 687-690. DOI: 10.1182/Blood.V84.3.687.687 |
0.491 |
|
| 1994 |
Rand M, Kalafatis M, Mann K. Platelet coagulation factor Va: the major secretory platelet phosphoprotein Blood. 83: 2180-2190. DOI: 10.1182/Blood.V83.8.2180.Bloodjournal8382180 |
0.481 |
|
| 1993 |
Xue J, Kalafatis M, Mann KG. Determination of the disulfide bridges in factor Va light chain. Biochemistry. 32: 5917-23. PMID 8504111 DOI: 10.1021/Bi00073A026 |
0.389 |
|
| 1993 |
Kalafatis M, Krishnaswamy S, Rand MD, Mann KG. Factor V. Methods in Enzymology. 222: 224-36. PMID 8412796 DOI: 10.1016/0076-6879(93)22016-9 |
0.5 |
|
| 1993 |
Kalafatis M, Rand M, Jenny R, Ehrlich Y, Mann K. Phosphorylation of factor Va and factor VIIIa by activated platelets Blood. 81: 704-719. DOI: 10.1182/blood.v81.3.704.704 |
0.355 |
|
| 1993 |
Kalafatis M, Rand M, Jenny R, Ehrlich Y, Mann K. Phosphorylation of factor Va and factor VIIIa by activated platelets Blood. 81: 704-719. DOI: 10.1182/Blood.V81.3.704.704 |
0.46 |
|
| 1988 |
Takahashi Y, Kalafatis M, Girma JP, Meyer D. Abnormality of the N-Terminal Portion of von Willebrand Factor in Type IIA and IIC von Willebrand Disease Thrombosis and Haemostasis. 60: 498-505. DOI: 10.1055/S-0038-1646999 |
0.364 |
|
| 1987 |
Takahashi Y, Kalafatis M, Girma J, Sewerin K, Andersson L, Meyer D. Localization of a factor VIII binding domain on a 34 kilodalton fragment of the N-terminal portion of von Willebrand factor Blood. 70: 1679-1682. DOI: 10.1182/Blood.V70.5.1679.Bloodjournal7051679 |
0.359 |
|
| 1987 |
Kalafatis M, Takahashi Y, Girma J, Meyer D. Localization of a collagen-interactive domain of human von Willebrand factor between amino acid residues Gly 911 and Glu 1,365 Blood. 70: 1577-1583. DOI: 10.1182/Blood.V70.5.1577.1577 |
0.426 |
|
| 1986 |
Girma J, Kalafatis M, Pietu G, Lavergne J, Chopek M, Edgington T, Meyer D. Mapping of distinct von Willebrand factor domains interacting with platelet GPIb and GPIIb/IIIa and with collagen using monoclonal antibodies Blood. 67: 1356-1366. DOI: 10.1182/Blood.V67.5.1356.Bloodjournal6751356 |
0.379 |
|
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