Year |
Citation |
Score |
2018 |
Zhao Y, Cushing PR, Smithson DC, Pellegrini M, Pletnev AA, Al-Ayyoubi S, Grassetti AV, Gerber SA, Guy RK, Madden DR. Correction: Cysteine modification reveals an allosteric inhibitory site on the CAL PDZ domain. Bioscience Reports. PMID 29871975 DOI: 10.1042/Bsr20180231_Cor |
0.672 |
|
2018 |
Zhao Y, Cushing PR, Smithson DC, Pellegrini M, Pletnev AA, Al-Ayyoubi S, Grassetti AV, Gerber SA, Guy RK, Madden DR. Cysteine modification reveals an allosteric inhibitory site on the CAL PDZ domain. Bioscience Reports. PMID 29472314 DOI: 10.1042/Bsr20180231 |
0.766 |
|
2014 |
Fitzpatrick JM, Pellegrini M, Cushing PR, Mierke DF. Small molecule inhibition of the Na(+)/H(+) exchange regulatory factor 1 and parathyroid hormone 1 receptor interaction. Biochemistry. 53: 5916-22. PMID 25171053 DOI: 10.1021/Bi500368K |
0.579 |
|
2014 |
Amacher JF, Cushing PR, Brooks L, Boisguerin P, Madden DR. Stereochemical preferences modulate affinity and selectivity among five PDZ domains that bind CFTR: comparative structural and sequence analyses. Structure (London, England : 1993). 22: 82-93. PMID 24210758 DOI: 10.1016/J.Str.2013.09.019 |
0.753 |
|
2013 |
Amacher JF, Cushing PR, Bahl CD, Beck T, Madden DR. Stereochemical determinants of C-terminal specificity in PDZ peptide-binding domains: a novel contribution of the carboxylate-binding loop. The Journal of Biological Chemistry. 288: 5114-26. PMID 23243314 DOI: 10.1074/Jbc.M112.401588 |
0.694 |
|
2012 |
Kundu R, Cushing PR, Popp BV, Zhao Y, Madden DR, Ball ZT. Hybrid organic-inorganic inhibitors of a PDZ interaction that regulates the endocytic fate of CFTR. Angewandte Chemie (International Ed. in English). 51: 7217-20. PMID 22700245 DOI: 10.1002/Anie.201202291 |
0.71 |
|
2012 |
Roberts KE, Cushing PR, Boisguerin P, Madden DR, Donald BR. Computational design of a PDZ domain peptide inhibitor that rescues CFTR activity. Plos Computational Biology. 8: e1002477. PMID 22532795 DOI: 10.1371/Journal.Pcbi.1002477 |
0.733 |
|
2011 |
Amacher JF, Cushing PR, Weiner JA, Madden DR. Crystallization and preliminary diffraction analysis of the CAL PDZ domain in complex with a selective peptide inhibitor. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 600-3. PMID 21543871 DOI: 10.1107/S1744309111009985 |
0.725 |
|
2011 |
Roberts KE, Cushing PR, Boisguerin P, Madden DR, Donald BR. Design of protein-protein interactions with a novel ensemble-based scoring algorithm Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 6577: 361-376. DOI: 10.1007/978-3-642-20036-6_35 |
0.658 |
|
2010 |
Cushing PR, Vouilleme L, Pellegrini M, Boisguerin P, Madden DR. A stabilizing influence: CAL PDZ inhibition extends the half-life of ΔF508-CFTR. Angewandte Chemie (International Ed. in English). 49: 9907-11. PMID 21105033 DOI: 10.1002/Anie.201005585 |
0.705 |
|
2010 |
Vouilleme L, Cushing PR, Volkmer R, Madden DR, Boisguerin P. Engineering peptide inhibitors to overcome PDZ binding promiscuity. Angewandte Chemie (International Ed. in English). 49: 9912-6. PMID 21105032 DOI: 10.1002/Anie.201005575 |
0.759 |
|
2008 |
Cushing PR, Fellows A, Villone D, Boisguérin P, Madden DR. The relative binding affinities of PDZ partners for CFTR: a biochemical basis for efficient endocytic recycling. Biochemistry. 47: 10084-98. PMID 18754678 DOI: 10.1021/Bi8003928 |
0.755 |
|
2007 |
Matheny CJ, Speck ME, Cushing PR, Zhou Y, Corpora T, Regan M, Newman M, Roudaia L, Speck CL, Gu TL, Griffey SM, Bushweller JH, Speck NA. Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles. The Embo Journal. 26: 1163-75. PMID 17290219 DOI: 10.1038/Sj.Emboj.7601568 |
0.377 |
|
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