Nathaniel W. Snyder, Ph.D. - Publications

Affiliations: 
2013 Pharmacology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Biochemistry, Pharmacy, Analytical Chemistry, Pharmacology

88 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Izzo LT, Trefely S, Demetriadou C, Drummond JM, Mizukami T, Kuprasertkul N, Farria AT, Nguyen PTT, Murali N, Reich L, Kantner DS, Shaffer J, Affronti H, Carrer A, Andrews A, ... ... Snyder NW, et al. Acetylcarnitine shuttling links mitochondrial metabolism to histone acetylation and lipogenesis. Science Advances. 9: eadf0115. PMID 37134161 DOI: 10.1126/sciadv.adf0115  0.314
2021 Anderson S, Xu P, Frey AJ, Goodspeed JR, Doan MT, Orris JJ, Clements N, Glassner MJ, Snyder NW. Cumulus cell acetyl-CoA metabolism from acetate is associated with maternal age but only partially with oocyte maturity. Systems Biology in Reproductive Medicine. 1-8. PMID 34962441 DOI: 10.1080/19396368.2021.2003479  0.302
2021 Trefely S, Huber K, Liu J, Noji M, Stransky S, Singh J, Doan MT, Lovell CD, von Krusenstiern E, Jiang H, Bostwick A, Pepper HL, Izzo L, Zhao S, Xu JP, ... ... Snyder NW, et al. Quantitative subcellular acyl-CoA analysis reveals distinct nuclear metabolism and isoleucine-dependent histone propionylation. Molecular Cell. PMID 34856123 DOI: 10.1016/j.molcel.2021.11.006  0.347
2021 Snyder NW, O Brien J, Singh B, Buchan G, Arroyo AD, Liu X, Bostwick A, Varner EL, Angajala A, Sobol RW, Blair IA, Mesaros C, Wendell SG. Primary saturation of α, β-unsaturated carbonyl containing fatty acids does not abolish electrophilicity. Chemico-Biological Interactions. 109689. PMID 34634267 DOI: 10.1016/j.cbi.2021.109689  0.472
2020 Varner EL, Trefely S, Bartee D, von Krusenstiern E, Izzo L, Bekeova C, O'Connor RS, Seifert EL, Wellen KE, Meier JL, Snyder NW. Quantification of lactoyl-CoA (lactyl-CoA) by liquid chromatography mass spectrometry in mammalian cells and tissues. Open Biology. 10: 200187. PMID 32961073 DOI: 10.1098/rsob.200187  0.315
2020 Zhao S, Jang C, Liu J, Uehara K, Gilbert M, Izzo L, Zeng X, Trefely S, Fernandez S, Carrer A, Miller KD, Schug ZT, Snyder NW, Gade TP, Titchenell PM, et al. Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate. Nature. 579: 586-591. PMID 32214246 DOI: 10.1038/S41586-020-2101-7  0.375
2020 Trefely S, Lovell CD, Snyder NW, Wellen KE. Compartmentalised acyl-CoA metabolism and roles in chromatin regulation. Molecular Metabolism. 100941. PMID 32199817 DOI: 10.1016/J.Molmet.2020.01.005  0.45
2020 Martinez Calejman C, Trefely S, Entwisle SW, Luciano A, Jung SM, Hsiao W, Torres A, Hung CM, Li H, Snyder NW, Villén J, Wellen KE, Guertin DA. mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis. Nature Communications. 11: 575. PMID 31996678 DOI: 10.1038/S41467-020-14430-W  0.381
2020 Dahl ES, Leon KE, Chen C, Jia Q, Buj R, Snyder NW, Aird KM. Abstract 1378: Targeting the metabolic-epigenetic axis to sensitize HR-proficient ovarian cancer to PARP inhibitors Cancer Research. 80: 1378-1378. DOI: 10.1158/1538-7445.Am2020-1378  0.331
2020 Lund P, Smith S, Simithy J, Chau L, Friedman E, Saiman Y, Gates L, Leboeuf M, Trefely S, Lopes M, Yuan Z, Janssen K, Kim M, Petucci C, Snyder N, et al. P165 INFLUENCE OF THE GUT MICROBIOTA ON COLONIC HISTONE MODIFICATIONS THROUGH BUTYRATE METABOLISM UNDER HEALTHY AND INFLAMMATORY CONDITIONS Gastroenterology. 158: S67. DOI: 10.1053/J.Gastro.2019.11.170  0.341
2019 Uribe-Herranz M, Rafail S, Beghi S, Gil-de-Gómez L, Verginadis I, Bittinger K, Pustylnikov S, Pierini S, Perales-Linares R, Blair IA, Mesaros CA, Snyder NW, Bushman F, Koumenis C, Facciabene A. Gut microbiota modulate dendritic cell antigen presentation and radiotherapy-induced antitumor immune response. The Journal of Clinical Investigation. PMID 31815742 DOI: 10.1172/Jci124332  0.469
2019 Trefely S, Liu J, Huber K, Doan MT, Jiang H, Singh J, von Krusenstiern E, Bostwick A, Xu P, Bogner-Strauss JG, Wellen KE, Snyder NW. Subcellular metabolic pathway kinetics are revealed by correcting for artifactual post harvest metabolism. Molecular Metabolism. 30: 61-71. PMID 31767181 DOI: 10.1016/J.Molmet.2019.09.004  0.442
2019 Trefely S, Doan MT, Snyder NW. Crosstalk between cellular metabolism and histone acetylation. Methods in Enzymology. 626: 1-21. PMID 31606071 DOI: 10.1016/Bs.Mie.2019.07.013  0.386
2019 Altinok O, Poggio JL, Stein DE, Bowne WB, Shieh AC, Snyder NW, Orynbayeva Z. Malate-aspartate shuttle promotes l-lactate oxidation in mitochondria. Journal of Cellular Physiology. PMID 31490559 DOI: 10.1002/Jcp.29160  0.349
2019 Buj R, Chen CW, Dahl ES, Leon KE, Kuskovsky R, Maglakelidze N, Navaratnarajah M, Zhang G, Doan MT, Jiang H, Zaleski M, Kutzler L, Lacko H, Lu Y, Mills GB, ... ... Snyder NW, et al. Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming. Cell Reports. 28: 1971-1980.e8. PMID 31433975 DOI: 10.1016/J.Celrep.2019.07.084  0.397
2019 Wellen KE, Snyder NW. Should we consider subcellular compartmentalization of metabolites, and if so, how do we measure them? Current Opinion in Clinical Nutrition and Metabolic Care. 22: 347-354. PMID 31365463 DOI: 10.1097/Mco.0000000000000580  0.42
2019 Kopinski PK, Janssen KA, Schaefer PM, Trefely S, Perry CE, Potluri P, Tintos-Hernandez JA, Singh LN, Karch KR, Campbell SL, Doan MT, Jiang H, Nissim I, Nakamaru-Ogiso E, Wellen KE, ... Snyder NW, et al. Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy. Proceedings of the National Academy of Sciences of the United States of America. PMID 31253706 DOI: 10.1073/Pnas.1906896116  0.331
2019 Wang W, Ishibashi J, Trefely S, Shao M, Cowan AJ, Sakers A, Lim HW, O'Connor S, Doan MT, Cohen P, Baur JA, King MT, Veech RL, Won KJ, Rabinowitz JD, ... Snyder NW, et al. A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate. Cell Metabolism. PMID 31155495 DOI: 10.1016/J.Cmet.2019.05.005  0.361
2019 Fernandez S, Viola JM, Torres A, Wallace M, Trefely S, Zhao S, Affronti HC, Gengatharan JM, Guertin DA, Snyder NW, Metallo CM, Wellen KE. Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females. Cell Reports. 27: 2772-2784.e6. PMID 31141698 DOI: 10.1016/J.Celrep.2019.04.112  0.393
2019 Dahl ES, Buj R, Leon KE, Newell JM, Imamura Y, Bitler BG, Snyder NW, Aird KM. Targeting IDH1 as a pro-senescent therapy in high-grade serous ovarian cancer. Molecular Cancer Research : McR. PMID 31110157 DOI: 10.1158/1541-7786.Mcr-18-1233  0.404
2019 Liu M, O'Connor RS, Trefely S, Graham K, Snyder NW, Beatty GL. Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47-mediated 'don't-eat-me' signal. Nature Immunology. PMID 30664738 DOI: 10.1038/S41590-018-0292-Y  0.411
2019 Lynch DR, Farmer J, Hauser L, Blair IA, Wang QQ, Mesaros C, Snyder N, Boesch S, Chin M, Delatycki MB, Giunti P, Goldsberry A, Hoyle C, McBride MG, Nachbauer W, et al. Safety, pharmacodynamics, and potential benefit of omaveloxolone in Friedreich ataxia. Annals of Clinical and Translational Neurology. 6: 15-26. PMID 30656180 DOI: 10.1002/Acn3.660  0.502
2019 Carrer A, Trefely S, Zhao S, Campbell S, Norgard RJ, Schultz KC, Sidoli S, Parris JLD, Affronti HC, Sivanand S, Egolf S, Sela Y, Trizzino M, Gardini A, Garcia BA, ... Snyder NW, et al. Acetyl-CoA metabolism supports multi-step pancreatic tumorigenesis. Cancer Discovery. PMID 30626590 DOI: 10.1158/2159-8290.Cd-18-0567  0.418
2019 Huber K, Hofer DC, Trefely S, Pelzmann HJ, Madreiter-Sokolowski C, Duta-Mare M, Schlager S, Trausinger G, Stryeck S, Graier WF, Kolb D, Magnes C, Snyder NW, Prokesch A, Kratky D, et al. N-acetylaspartate pathway is nutrient responsive and coordinates lipid and energy metabolism in brown adipocytes. Biochimica Et Biophysica Acta. Molecular Cell Research. 1866: 337-348. PMID 30595160 DOI: 10.1016/J.Bbamcr.2018.08.017  0.44
2019 Dahl ES, Snyder NW, Aird KM. Abstract GMM-022: IDH1 IS A PRO-SENESCENT THERAPY IN HIGH-GRADE SEROUS OVARIAN CANCER Clinical Cancer Research. 25. DOI: 10.1158/1557-3265.Ovcasymp18-Gmm-022  0.396
2019 Carrer A, Trefely S, Zhao S, Campbell S, Sela Y, Sidoli S, Garcia BA, Snyder NW, Stanger BZ, Wellen KE. Abstract A03: All the roads bring to Rome: How acetyl-CoA metabolism supports multistep pancreatic carcinogenesis Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-A03  0.424
2018 Kuskovsky R, Buj R, Xu P, Hofbauer S, Doan MT, Jiang H, Bostwick A, Mesaros C, Aird KM, Snyder NW. Simultaneous isotope dilution quantification and metabolic tracing of deoxyribonucleotides by liquid chromatography high resolution mass spectrometry. Analytical Biochemistry. 568: 65-72. PMID 30605633 DOI: 10.1016/J.Ab.2018.12.023  0.416
2018 O'Neill K, Alexander J, Azuma R, Xiao R, Snyder NW, Mesaros CA, Blair IA, Pinney SE. Gestational Diabetes Alters the Metabolomic Profile in 2nd Trimester Amniotic Fluid in a Sex-Specific Manner. International Journal of Molecular Sciences. 19. PMID 30201937 DOI: 10.3390/Ijms19092696  0.554
2018 Tenopoulou M, Doulias PT, Nakamoto K, Berrios K, Zura G, Li C, Faust M, Yakovishina V, Evans P, Tan L, Bennett MJ, Snyder NW, Quinn WJ, Baur JA, Atochin DN, et al. Oral nitrite restores age-dependent phenotypes in eNOS-null mice. Jci Insight. 3. PMID 30135317 DOI: 10.1172/Jci.Insight.122156  0.405
2018 Trefely S, Mesaros C, Xu P, Doan MT, Jiang H, Altinok O, Orynbayeva Z, Snyder NW. Artefactual formation of pyruvate from in-source conversion of lactate. Rapid Communications in Mass Spectrometry : Rcm. PMID 29740888 DOI: 10.1002/Rcm.8159  0.419
2018 Sinclair WR, Shrimp JH, Zengeya TT, Kulkarni RA, Garlick JM, Luecke H, Worth AJ, Blair IA, Snyder NW, Meier JL. Bioorthogonal pro-metabolites for profiling short chain fatty acylation. Chemical Science. 9: 1236-1241. PMID 29675169 DOI: 10.1039/C7Sc00247E  0.571
2018 O'Connor RS, Guo L, Ghassemi S, Snyder NW, Worth AJ, Weng L, Kam Y, Philipson B, Trefely S, Nunez-Cruz S, Blair IA, June CH, Milone MC. The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations. Scientific Reports. 8: 6289. PMID 29674640 DOI: 10.1038/S41598-018-24676-6  0.534
2018 Lee JV, Berry CT, Kim K, Sen P, Kim T, Carrer A, Trefely S, Zhao S, Fernandez S, Barney LE, Schwartz AD, Peyton SR, Snyder NW, Berger SL, Freedman BD, et al. Acetyl-CoA promotes glioblastoma cell adhesion and migration through Ca-NFAT signaling. Genes & Development. PMID 29674394 DOI: 10.1101/Gad.311027.117  0.352
2018 Wang Q, Guo L, Strawser CJ, Hauser LA, Hwang WT, Snyder NW, Lynch DR, Mesaros C, Blair IA. Low apolipoprotein A-I levels in Friedreich's ataxia and in frataxin-deficient cells: Implications for therapy. Plos One. 13: e0192779. PMID 29447225 DOI: 10.1371/Journal.Pone.0192779  0.495
2018 Anderson S, Snyder N, Bloom A, Brasile D, Gocial B, Orris J, Glassner M. Cumulus cell acetyl-CoA enrichment from acetate found to decrease with maternal age using a novel approach to measure metabolism in individual cumulus cell complexes Fertility and Sterility. 110: e107-e108. DOI: 10.1016/J.Fertnstert.2018.07.326  0.373
2017 Shrimp JH, Garlick J, Tezil T, Sorum AW, Worth AJ, Blair IA, Verdin E, Snyder NW, Meier JL. Defining metabolic and non-metabolic regulation of histone acetylation by a NSAID chemotype. Molecular Pharmaceutics. PMID 29240439 DOI: 10.1021/Acs.Molpharmaceut.7B00943  0.581
2017 Frederick DW, Trefely S, Buas A, Goodspeed J, Singh J, Mesaros C, Baur JA, Snyder NW. Stable isotope labeling by essential nutrients in cell culture (SILEC) for accurate measurement of nicotinamide adenine dinucleotide metabolism. The Analyst. PMID 29072717 DOI: 10.1039/C7An01378G  0.402
2017 Simithy J, Sidoli S, Yuan ZF, Coradin M, Bhanu NV, Marchione DM, Klein BJ, Bazilevsky GA, McCullough CE, Magin RS, Kutateladze TG, Snyder NW, Marmorstein R, Garcia BA. Characterization of histone acylations links chromatin modifications with metabolism. Nature Communications. 8: 1141. PMID 29070843 DOI: 10.1038/S41467-017-01384-9  0.345
2017 Liu J, Zhao R, Ye Z, Frey AJ, Schriver ER, Snyder NW, Hebbring SJ. Relationship of SULT1A1 Copy Number Variation with Estrogen Metabolism and Human Health. The Journal of Steroid Biochemistry and Molecular Biology. PMID 28867356 DOI: 10.1016/J.Jsbmb.2017.08.017  0.342
2017 Sims C, Salliant N, Worth AJ, Parry R, Mesaros C, Blair IA, Snyder NW. Metabolic tracing analysis reveals substrate-specific metabolic deficits in platelet storage lesion. Transfusion. PMID 28836286 DOI: 10.1111/Trf.14292  0.532
2017 Else T, Marcondes Lerario A, Everett J, Haymon L, Wham D, Mullane M, Wilson TL, Rainville I, Rana H, Worth AJ, Snyder NW, Blair IA, McKay R, Kilbridge K, Hammer GD, et al. Adrenocortical carcinoma and succinate dehydrogenase gene mutations. European Journal of Endocrinology. PMID 28819017 DOI: 10.1530/Eje-17-0358  0.426
2017 Xu R, Mesaros C, Weng L, Snyder NW, Vachani A, Blair IA, Hwang WT. Comparison of statistical methods for detection of serum lipid biomarkers for mesothelioma and asbestos exposure. Biomarkers in Medicine. PMID 28534416 DOI: 10.2217/Bmm-2017-0087  0.464
2017 Mesaros C, Arroyo AD, Blair IA, Snyder NW. Coenzyme A thioester formation of 11- and 15-oxo-eicosatetraenoic acid. Prostaglandins & Other Lipid Mediators. PMID 28238887 DOI: 10.1016/J.Prostaglandins.2017.02.004  0.588
2017 Kulkarni RA, Worth AJ, Zengeya TT, Shrimp JH, Garlick JM, Roberts AM, Montgomery DC, Sourbier C, Gibbs BK, Mesaros C, Tsai YC, Das S, Chan KC, Zhou M, Andresson T, ... ... Snyder NW, et al. Discovering Targets of Non-enzymatic Acylation by Thioester Reactivity Profiling. Cell Chemical Biology. PMID 28163016 DOI: 10.1016/J.Chembiol.2017.01.002  0.515
2017 Carrer A, Parris JL, Trefely S, Henry RA, Montgomery DC, Torres A, Viola JM, Kuo YM, Blair IA, Meier JL, Andrews AJ, Snyder NW, Wellen KE. Impact of High Fat Diet on Tissue Acyl-CoA and Histone Acetylation Levels. The Journal of Biological Chemistry. PMID 28077572 DOI: 10.1074/Jbc.M116.750620  0.516
2016 Kawalekar OU, O' Connor RS, Fraietta JA, Guo L, McGettigan SE, Posey AD, Patel PR, Guedan S, Scholler J, Keith B, Snyder NW, Blair IA, Milone MC, June CH. Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells. Immunity. 44: 712. PMID 28843072 DOI: 10.1016/j.immuni.2016.02.023  0.464
2016 Trefely S, Ashwell P, Snyder NW. FluxFix: automatic isotopologue normalization for metabolic tracer analysis. Bmc Bioinformatics. 17: 485. PMID 27887574 DOI: 10.1186/S12859-016-1360-7  0.397
2016 Frey AJ, Park BY, Schriver ER, Feldman DR, Parry S, Croen LA, Fallin DM, Hertz-Picciotto I, Newschaffer CJ, Snyder NW. Differences in testosterone and its precursors by sex of the offspring in meconium. The Journal of Steroid Biochemistry and Molecular Biology. PMID 27871978 DOI: 10.1016/J.Jsbmb.2016.11.010  0.312
2016 Pinney SE, Mesaros CA, Snyder NW, Busch CM, Xiao R, Aijaz S, Ijaz N, Blair IA, Manson JM. Second trimester amniotic fluid bisphenol a concentration is associated with decreased birth weight in term infants. Reproductive Toxicology (Elmsford, N.Y.). PMID 27829162 DOI: 10.1016/J.Reprotox.2016.11.007  0.449
2016 Zhao S, Torres A, Henry RA, Trefely S, Wallace M, Lee JV, Carrer A, Sengupta A, Campbell SL, Kuo YM, Frey AJ, Meurs N, Viola JM, Blair IA, Weljie AM, ... ... Snyder NW, et al. ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch. Cell Reports. 17: 1037-1052. PMID 27760311 DOI: 10.1016/J.Celrep.2016.09.069  0.603
2016 Frey AJ, Wang Q, Busch C, Feldman D, Bottalico L, Mesaros CA, Blair IA, Vachani A, Snyder NW. Validation of highly sensitive simultaneous targeted and untargeted analysis of keto-steroids by Girard P derivatization and stable isotope dilution-liquid chromatography-high resolution mass spectrometry. Steroids. PMID 27743906 DOI: 10.1016/J.Steroids.2016.10.003  0.503
2016 Guo L, Worth AJ, Mesaros C, Snyder NW, Glickson JD, Blair IA. Diisopropylethylamine/hexafluoroisopropanol-mediated ion-pairing ultra-high-performance liquid chromatography/mass spectrometry for phosphate and carboxylate metabolite analysis: utility for studying cellular metabolism. Rapid Communications in Mass Spectrometry : Rcm. 30: 1835-45. PMID 27476658 DOI: 10.1002/Rcm.7667  0.584
2016 Saha A, O'Connor RS, Thangavelu G, Lovitch SB, Dandamudi DB, Wilson CB, Vincent BG, Tkachev V, Pawlicki JM, Furlan SN, Kean LS, Aoyama K, Taylor PA, Panoskaltsis-Mortari A, Foncea R, ... ... Snyder NW, et al. Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality. The Journal of Clinical Investigation. PMID 27294527 DOI: 10.1172/Jci85796  0.456
2016 Worth AJ, Marchione DM, Parry RC, Wang Q, Gillespie KP, Saillant NN, Sims C, Mesaros C, Snyder NW, Blair IA. LC-MS Analysis of Human Platelets as a Platform for Studying Mitochondrial Metabolism. Journal of Visualized Experiments : Jove. PMID 27077278 DOI: 10.3791/53941  0.601
2016 Daurio NA, Tuttle SW, Worth AJ, Song EY, Davis JM, Snyder NW, Blair IA, Koumenis C. AMPK activation and metabolic reprogramming by tamoxifen through estrogen receptor-independent mechanisms suggests new uses for this therapeutic modality in cancer treatment. Cancer Research. PMID 27020861 DOI: 10.1158/0008-5472.Can-15-2197  0.557
2016 Frey AJ, Feldman DR, Trefely S, Worth AJ, Basu SS, Snyder NW. LC-quadrupole/Orbitrap high-resolution mass spectrometry enables stable isotope-resolved simultaneous quantification and (13)C-isotopic labeling of acyl-coenzyme A thioesters. Analytical and Bioanalytical Chemistry. PMID 26968563 DOI: 10.1007/S00216-016-9448-5  0.707
2016 Covarrubias AJ, Aksoylar HI, Yu J, Snyder NW, Worth AJ, Iyer SS, Wang J, Ben-Sahra I, Byles V, Polynne-Stapornkul T, Espinosa EC, Lamming D, Manning BD, Zhang Y, Blair IA, et al. Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation. Elife. 5. PMID 26894960 DOI: 10.7554/Elife.11612  0.542
2016 Kawalekar OU, O'Connor RS, Fraietta JA, Guo L, McGettigan SE, Posey AD, Patel PR, Guedan S, Scholler J, Keith B, Snyder N, Blair I, Milone MC, June CH. Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells. Immunity. 44: 380-390. PMID 26885860 DOI: 10.1016/J.Immuni.2016.01.021  0.501
2016 Bedi KC, Snyder NW, Brandimarto J, Aziz M, Mesaros C, Worth A, Wang L, Javaheri A, Blair IA, Margulies K, Rame JE. Evidence for Intramyocardial Disruption of Lipid Metabolism and Increased Myocardial Ketone Utilization in Advanced Human Heart Failure. Circulation. PMID 26819374 DOI: 10.1161/Circulationaha.115.017545  0.523
2016 Carrer A, Lee JV, Shah S, Aiello NM, Snyder NW, Worth AJ, Blair IA, Stanger BZ, Wellen KE. Abstract PR03: Exploring the link between Kras and histone acetylation Cancer Research. 76. DOI: 10.1158/1538-7445.Chromepi15-Pr03  0.555
2016 Kawalekar OU, O' Connor RS, Fraietta JA, Guo L, McGettigan SE, Posey AD, Patel PR, Guedan S, Scholler J, Keith B, Snyder NW, Blair IA, Milone MC, June CH. Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells [Immunity 44, 380-390, (2016)] Immunity. 44: 712. DOI: 10.1016/j.immuni.2016.02.023  0.458
2015 Wang Q, Zhang S, Guo L, Busch CM, Jian W, Weng N, Snyder NW, Rangiah K, Mesaros C, Blair IA. Serum apolipoprotein A-1 quantification by LC-MS with a SILAC internal standard reveals reduced levels in smokers. Bioanalysis. PMID 26394123 DOI: 10.4155/Bio.15.195  0.612
2015 Snyder NW, Mesaros C, Blair IA. Translational metabolomics in cancer research. Biomarkers in Medicine. 9: 821-34. PMID 26329905 DOI: 10.2217/Bmm.15.52  0.48
2015 Worth AJ, Basu SS, Deutsch EC, Hwang WT, Snyder NW, Lynch DR, Blair IA. Stable isotopes and LC-MS for monitoring metabolic disturbances in Friedreich's ataxia platelets. Bioanalysis. 7: 1843-55. PMID 26295986 DOI: 10.4155/Bio.15.118  0.72
2015 Mesaros C, Worth AJ, Snyder NW, Christofidou-Solomidou M, Vachani A, Albelda SM, Blair IA. Bioanalytical techniques for detecting biomarkers of response to human asbestos exposure. Bioanalysis. 7: 1157-73. PMID 26039812 DOI: 10.4155/Bio.15.53  0.458
2015 Cossette C, Gravel S, Reddy CN, Gore V, Chourey S, Ye Q, Snyder NW, Mesaros CA, Blair IA, Lavoie JP, Reinero CR, Rokach J, Powell WS. Biosynthesis and actions of 5-oxoeicosatetraenoic acid (5-oxo-ETE) on feline granulocytes. Biochemical Pharmacology. 96: 247-55. PMID 26032638 DOI: 10.1016/J.Bcp.2015.05.009  0.464
2015 Aird KM, Worth AJ, Snyder NW, Lee JV, Sivanand S, Liu Q, Blair IA, Wellen KE, Zhang R. ATM couples replication stress and metabolic reprogramming during cellular senescence. Cell Reports. 11: 893-901. PMID 25937285 DOI: 10.1016/J.Celrep.2015.04.014  0.539
2015 Worth AJ, Gillespie KP, Mesaros C, Guo L, Basu SS, Snyder NW, Blair IA. Rotenone Stereospecifically Increases (S)-2-Hydroxyglutarate in SH-SY5Y Neuronal Cells. Chemical Research in Toxicology. 28: 948-54. PMID 25800467 DOI: 10.1021/Tx500535C  0.708
2015 Wang Q, Rangiah K, Mesaros C, Snyder NW, Vachani A, Song H, Blair IA. Ultrasensitive quantification of serum estrogens in postmenopausal women and older men by liquid chromatography-tandem mass spectrometry. Steroids. 96: 140-52. PMID 25637677 DOI: 10.1016/J.Steroids.2015.01.014  0.488
2015 Snyder NW, Tombline G, Worth AJ, Parry RC, Silvers JA, Gillespie KP, Basu SS, Millen J, Goldfarb DS, Blair IA. Production of stable isotope-labeled acyl-coenzyme A thioesters by yeast stable isotope labeling by essential nutrients in cell culture. Analytical Biochemistry. 474: 59-65. PMID 25572876 DOI: 10.1016/J.Ab.2014.12.014  0.718
2015 Snyder NW, Golin-Bisello F, Gao Y, Blair IA, Freeman BA, Wendell SG. 15-Oxoeicosatetraenoic acid is a 15-hydroxyprostaglandin dehydrogenase-derived electrophilic mediator of inflammatory signaling pathways. Chemico-Biological Interactions. 234: 144-53. PMID 25450232 DOI: 10.1016/J.Cbi.2014.10.029  0.545
2015 Snyder NW, Basu SS, Worth AJ, Mesaros C, Blair IA. Metabolism of propionic acid to a novel acyl-coenzyme A thioester by mammalian cell lines and platelets. Journal of Lipid Research. 56: 142-50. PMID 25424005 DOI: 10.1194/Jlr.M055384  0.732
2015 Covarrubias AJ, Aksoylar HI, Yu J, Snyder NW, Worth AJ, Iyer SS, Wang J, Ben-Sahra I, Byles V, Polynne-Stapornkul T, Espinosa EC, Lamming D, Manning BD, Zhang Y, Blair IA, et al. Author response: Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation Elife. DOI: 10.7554/Elife.11612.024  0.511
2015 Mesaros C, Worth AJ, Snyder NW, Christofidou-Solomidou M, Vachani A, Albelda SM, Blair IA. Bioanalytical techniques for detecting biomarkers of response to human asbestos exposure Bioanalysis. 7: 1157-1173. DOI: 10.4155/bio.15.53  0.366
2015 Saha A, O'Connor RS, Thangavelu G, Lovitch SB, Dandamudi DB, Wilson CB, Vincent BG, Aoyama K, Taylor PA, Panoskaltsis-Mortari A, Foncea R, Burrill JS, Guo L, Sacristan C, Furlan SN, ... Snyder NW, et al. Loss of Programmed Death Ligand-1 Expression on Donor T Cells Lessens Acute Graft-Versus-Host Disease Lethality Blood. 126: 147-147. DOI: 10.1182/Blood.V126.23.147.147  0.454
2015 Shah S, Lee JV, Carrer A, Snyder NW, Wellen KE. Abstract A31: Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation Molecular Cancer Therapeutics. 14. DOI: 10.1158/1538-8514.Pi3K14-A31  0.389
2015 Carrer A, Lee JV, Shah S, Snyder NW, Jackson E, Aiello NM, Garcia BA, Chodosh LA, Stanger BZ, Blair IA, Wellen KE. Abstract B40: Oncogenic Kras induces histone acetylation in pancreatic ductal adenocarcinoma Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-B40  0.562
2015 Rame J, Bedi K, Snyder N, Brandimarto J, Mesaros C, Birati E, Blair I, Margulies K. Myocardial Lipid Metabolism in the End-Stage Failing: Heart: Evidence for an Energy-Starved State The Journal of Heart and Lung Transplantation. 34: S89-S90. DOI: 10.1016/J.Healun.2015.01.239  0.494
2015 Aird KM, Worth AJ, Snyder NW, Lee JV, Sivanand S, Liu Q, Blair IA, Wellen KE, Zhang R. ATM Couples Replication Stress and Metabolic Reprogramming during Cellular Senescence Cell Reports. 11: 893-901. DOI: 10.1016/j.celrep.2015.04.014  0.452
2014 Snyder NW, Basu SS, Zhou Z, Worth AJ, Blair IA. Stable isotope dilution liquid chromatography/mass spectrometry analysis of cellular and tissue medium- and long-chain acyl-coenzyme A thioesters. Rapid Communications in Mass Spectrometry : Rcm. 28: 1840-8. PMID 25559454 DOI: 10.1002/Rcm.6958  0.691
2014 Worth AJ, Basu SS, Snyder NW, Mesaros C, Blair IA. Inhibition of neuronal cell mitochondrial complex I with rotenone increases lipid β-oxidation, supporting acetyl-coenzyme A levels. The Journal of Biological Chemistry. 289: 26895-903. PMID 25122772 DOI: 10.1074/Jbc.M114.591354  0.726
2014 Lee JV, Carrer A, Shah S, Snyder NW, Wei S, Venneti S, Worth AJ, Yuan ZF, Lim HW, Liu S, Jackson E, Aiello NM, Haas NB, Rebbeck TR, Judkins A, et al. Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation. Cell Metabolism. 20: 306-19. PMID 24998913 DOI: 10.1016/J.Cmet.2014.06.004  0.541
2013 Snyder NW, Revello SD, Liu X, Zhang S, Blair IA. Cellular uptake and antiproliferative effects of 11-oxo-eicosatetraenoic acid. Journal of Lipid Research. 54: 3070-7. PMID 23945567 DOI: 10.1194/Jlr.M040741  0.514
2013 Snyder NW, Khezam M, Mesaros CA, Worth A, Blair IA. Untargeted metabolomics from biological sources using ultraperformance liquid chromatography-high resolution mass spectrometry (UPLC-HRMS). Journal of Visualized Experiments : Jove. e50433. PMID 23711563 DOI: 10.3791/50433  0.519
2013 VerMilyea M, Mesaros C, Snyder N, Blair I, Coutifaris C. Is there an increase in non-voc leachates from disposable sterile IVF culture plasticware over time? Fertility and Sterility. 100: S252. DOI: 10.1016/J.Fertnstert.2013.07.1190  0.418
2012 Snyder NW, Revello SD, Liu X, Zhang S, Arora JS, Blair IA. Abstract LB-9: Cyclooxygenase-2/15-prostaglandin dehydrogenase derived endogenous canonical NF-κB inhibitors Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-9  0.514
2012 Revello SD, Snyder NW, Liu X, Zhang S, Arora JS, Blair IA. Abstract LB-10: Distribution and potency of anti-proliferative arachidonic acid metabolites Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-10  0.551
2011 Liu X, Zhang S, Arora JS, Snyder NW, Shah SJ, Blair IA. 11-Oxoeicosatetraenoic acid is a cyclooxygenase-2/15-hydroxyprostaglandin dehydrogenase-derived antiproliferative eicosanoid. Chemical Research in Toxicology. 24: 2227-36. PMID 21916491 DOI: 10.1021/Tx200336F  0.544
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