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Amy E. Moritz, Ph.D. - Publications

Affiliations: 
2011 The University of North Dakota, Grand Forks, ND, United States 
Area:
Biochemistry
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22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Sánchez-Soto M, Boldizsar NM, Schardien KA, Madaras NS, Willette BKA, Inbody LR, Dasaro C, Moritz AE, Drube J, Haider RS, Free RB, Hoffman C, Sibley DR. G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation. Biomolecules. 13. PMID 37892234 DOI: 10.3390/biom13101552  0.613
2023 Sibley DR, Nilson AN, Moritz AE, Shi L. Dopamine receptor divergence revealed using a common ligand. Trends in Pharmacological Sciences. PMID 37599183 DOI: 10.1016/j.tips.2023.08.002  0.61
2023 Enriquez-Traba J, Yarur-Castillo HE, Flores RJ, Weil T, Roy S, Usdin TB, LaGamma CT, Arenivar M, Wang H, Tsai VS, Moritz AE, Sibley DR, Moratalla R, Freyberg ZZ, Tejeda HA. Dissociable control of motivation and reinforcement by distinct ventral striatal dopamine receptors. Biorxiv : the Preprint Server For Biology. PMID 37425766 DOI: 10.1101/2023.06.27.546539  0.621
2023 Mayer FP, Stewart A, Varman DR, Moritz AE, Foster JD, Owens AW, Areal LB, Gowrishankar R, Velez M, Wickham K, Phelps H, Katamish R, Rabil M, Jayanthi LD, Vaughan RA, et al. Kappa Opioid Receptor Antagonism Rescues Genetic Perturbation of Dopamine Homeostasis: Molecular, Physiological and Behavioral Consequences. Biorxiv : the Preprint Server For Biology. PMID 37205452 DOI: 10.1101/2023.05.03.539310  0.626
2023 Moritz AE, Madaras NS, Rankin ML, Inbody LR, Sibley DR. Delineation of G Protein-Coupled Receptor Kinase Phosphorylation Sites within the D Dopamine Receptor and Their Roles in Modulating β-Arrestin Binding and Activation. International Journal of Molecular Sciences. 24. PMID 37047571 DOI: 10.3390/ijms24076599  0.641
2020 Moritz AE, Bonifazi A, Guerrero AM, Kumar V, Free RB, Lane JR, Verma RK, Shi L, Newman AH, Sibley DR. Evidence for a stereoselective mechanism for bitopic activity by extended-length antagonists of the D3 dopamine receptor. Acs Chemical Neuroscience. PMID 32969645 DOI: 10.1021/acschemneuro.0c00425  0.656
2020 Moritz AE, Free RB, Weiner WS, Akano EO, Gandhi D, Abramyan A, Keck TM, Ferrer M, Hu X, Southall N, Steiner J, Aubé J, Shi L, Frankowski KJ, Sibley DR. Discovery, Optimization and Characterization of ML417: A Novel and Highly Selective D3 Dopamine Receptor Agonist. Journal of Medicinal Chemistry. PMID 32342685 DOI: 10.1021/Acs.Jmedchem.0C00424  0.768
2020 Sanchez-Soto M, Verma RK, Willette BKA, Gonye EC, Moore AM, Moritz AE, Boateng CA, Yano H, Free RB, Shi L, Sibley DR. A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity. Science Signaling. 13. PMID 32019899 DOI: 10.1126/Scisignal.Aaw5885  0.631
2020 Akano EO, Casazza JA, Dranchak P, Moritz AE, Free RB, Inglese J, Sibley DR. Development of a dopaminergic neurodegeneration assay using laser cytometry of Caenorhabditis elegans models of Parkinson’s disease The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02481  0.693
2020 Moritz AE, Inbody LR, Gandhi DM, Akano E, Fearce C, Free RB, Barnaeva ES, Hu X, Southall NT, Ferrer M, Keck TM, Frankowski KJ, Sibley DR. Structure‐Activity Relationships of a Negative Allosteric Modulator of the D3 Dopamine Receptor and Investigation of its Binding Site The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02441  0.771
2019 Bolland DE, Moritz AE, Stanislowski DJ, Vaughan DR, Foster JD. Palmitoylation by multiple DHHC enzymes enhances dopamine transporter function and stability. Acs Chemical Neuroscience. PMID 30965003 DOI: 10.1021/Acschemneuro.8B00558  0.314
2018 Luderman KD, Conroy JL, Free RB, Southall N, Ferrer M, Sanchez-Soto M, Moritz AE, Willette BKA, Fyfe TJ, Jain P, Titus S, Hazelwood LA, Aube J, Lane JR, Frankowski KJ, et al. Identification of positive allosteric modulators of the D1 dopamine receptor that act at diverse binding sites. Molecular Pharmacology. PMID 30068735 DOI: 10.1124/Mol.118.113175  0.714
2018 Chun LS, Vekariya RH, Free RB, Li Y, Lin DT, Su P, Liu F, Namkung Y, Laporte SA, Moritz AE, Aubé J, Frankowski KJ, Sibley DR. Structure-Activity Investigation of a G Protein-Biased Agonist Reveals Molecular Determinants for Biased Signaling of the DDopamine Receptor. Frontiers in Synaptic Neuroscience. 10: 2. PMID 29515433 DOI: 10.3389/Fnsyn.2018.00002  0.614
2017 Moritz AE, Benjamin Free R, Sibley DR. Advances and challenges in the search for D2 and D3 dopamine receptor-selective compounds. Cellular Signalling. PMID 28716664 DOI: 10.1016/J.Cellsig.2017.07.003  0.674
2017 Kumar V, Moritz AE, Keck TM, Bonifazi A, Ellenberger MP, Sibley CD, Free RB, Shi L, Lane JR, Sibley DR, Newman AH. Synthesis and Pharmacological Characterization of Novel trans-Cyclopropylmethyl-Linked Bivalent Ligands That Exhibit Selectivity and Allosteric Pharmacology at the Dopamine D3 Receptor (D3R). Journal of Medicinal Chemistry. PMID 28186762 DOI: 10.1021/Acs.Jmedchem.6B01688  0.661
2015 Moritz AE, Rastedt DE, Stanislowski DJ, Shetty M, Smith MA, Vaughan RA, Foster JD. Reciprocal Phosphorylation and Palmitoylation Control Dopamine Transporter Kinetics. The Journal of Biological Chemistry. PMID 26424792 DOI: 10.1074/Jbc.M115.667055  0.636
2015 Meade JA, Free RB, Miller NR, Chun LS, Doyle TB, Moritz AE, Conroy JL, Watts VJ, Sibley DR. (-)-Stepholidine is a potent pan-dopamine receptor antagonist of both G protein- and β-arrestin-mediated signaling. Psychopharmacology. 232: 917-30. PMID 25231919 DOI: 10.1007/S00213-014-3726-8  0.687
2014 Furman CA, Roof RA, Moritz AE, Miller BN, Doyle TB, Free RB, Banala AK, Paul NM, Kumar V, Sibley CD, Newman AH, Sibley DR. Investigation of the binding and functional properties of extended length D3 dopamine receptor-selective antagonists. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 25583363 DOI: 10.1016/J.Euroneuro.2014.11.013  0.701
2014 Free RB, Chun LS, Moritz AE, Miller BN, Doyle TB, Conroy JL, Padron A, Meade JA, Xiao J, Hu X, Dulcey AE, Han Y, Duan L, Titus S, Bryant-Genevier M, et al. Discovery and characterization of a G protein-biased agonist that inhibits β-arrestin recruitment to the D2 dopamine receptor. Molecular Pharmacology. 86: 96-105. PMID 24755247 DOI: 10.1124/Mol.113.090563  0.705
2013 Moritz AE, Foster JD, Gorentla BK, Mazei-Robison MS, Yang JW, Sitte HH, Blakely RD, Vaughan RA. Phosphorylation of dopamine transporter serine 7 modulates cocaine analog binding. The Journal of Biological Chemistry. 288: 20-32. PMID 23161550 DOI: 10.1074/Jbc.M112.407874  0.751
2012 Foster JD, Yang JW, Moritz AE, Challasivakanaka S, Smith MA, Holy M, Wilebski K, Sitte HH, Vaughan RA. Dopamine transporter phosphorylation site threonine 53 regulates substrate reuptake and amphetamine-stimulated efflux. The Journal of Biological Chemistry. 287: 29702-12. PMID 22722938 DOI: 10.1186/2050-6511-13-S1-A45  0.673
2009 Gorentla BK, Moritz AE, Foster JD, Vaughan RA. Proline-directed phosphorylation of the dopamine transporter N-terminal domain. Biochemistry. 48: 1067-76. PMID 19146407 DOI: 10.1021/Bi801696N  0.743
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