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Michael A. Bukys, Ph.D. - Publications

Affiliations: 
2008 Cleveland State University, Cleveland, OH, United States 
Area:
Biochemistry
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Qu X, Afelik S, Jensen JN, Bukys MA, Kobberup S, Schmerr M, Xiao F, Nyeng P, Veronica Albertoni M, Grapin-Botton A, Jensen J. Notch-mediated post-translational control of Ngn3 protein stability regulates pancreatic patterning and cell fate commitment. Developmental Biology. 376: 1-12. PMID 23370147 DOI: 10.1016/J.Ydbio.2013.01.021  0.301
2010 Hirbawi J, Vaughn JL, Bukys MA, Vos HL, Kalafatis M. Contribution of amino acid region 659-663 of Factor Va heavy chain to the activity of factor Xa within prothrombinase . Biochemistry. 49: 8520-34. PMID 20722419 DOI: 10.1021/Bi101097T  0.802
2010 Vaughn JL, Hirbawi J, Bukys MA, Kalafatis M. Role of the N-Terminal Amino Acid Region of Factor Va Light Chain In Prothrombinase Assembly and Function. Blood. 116: 1127-1127. DOI: 10.1182/Blood.V116.21.1127.1127  0.771
2008 Barhoover MA, Orban T, Bukys MA, Kalafatis M. Cooperative regulation of the activity of factor Xa within prothrombinase by discrete amino acid regions from factor Va heavy chain. Biochemistry. 47: 12835-43. PMID 18991406 DOI: 10.1021/Bi801241R  0.805
2008 Hirbawi J, Bukys MA, Barhoover MA, Erdogan E, Kalafatis M. Role of the acidic hirudin-like COOH-terminal amino acid region of factor Va heavy chain in the enhanced function of prothrombinase. Biochemistry. 47: 7963-74. PMID 18590276 DOI: 10.1021/Bi800593K  0.822
2008 Barhoover MA, Orban T, Beck DO, Bukys MA, Kalafatis M. Contribution of amino acid region 334-335 from factor Va heavy chain to the catalytic efficiency of prothrombinase. Biochemistry. 47: 6840-50. PMID 18537263 DOI: 10.1021/Bi800057R  0.802
2008 Bukys MA, Orban T, Kim PY, Nesheim ME, Kalafatis M. The interaction of fragment 1 of prothrombin with the membrane surface is a prerequisite for optimum expression of factor Va cofactor activity within prothrombinase. Thrombosis and Haemostasis. 99: 511-22. PMID 18327399 DOI: 10.1160/Th07-08-0532  0.788
2008 Erdogan E, Bukys MA, Kalafatis M. The contribution of amino acid residues 1508-1515 of factor V to light chain generation. Journal of Thrombosis and Haemostasis : Jth. 6: 118-24. PMID 17944989 DOI: 10.1111/J.1538-7836.2007.02803.X  0.807
2008 Kalafatis M, Hirbawi J, Barhoover MA, Bukys MA. The Effect of Factor Va on Prothrombinase Function Blood. 112: 1020-1020. DOI: 10.1182/Blood.V112.11.1020.1020  0.812
2007 Erdogan E, Bukys MA, Orfeo T, Mann KG, Kalafatis M. Identification of an inactivating cleavage site for alpha-thrombin on the heavy chain of factor Va. Thrombosis and Haemostasis. 98: 998-1006. PMID 18000604 DOI: 10.1160/Th07-06-0431  0.766
2007 Bukys MA, Orban T, Kim PY, Nesheim ME, Kalafatis M. Factor Va Cofactor Activity Is Dependent on the Interaction of Prothrombin with the Membrane Surface. Blood. 110: 2702-2702. DOI: 10.1182/Blood.V110.11.2702.2702  0.793
2007 Kalafatis M, Bukys MA, Hirbawi J, Kim PY, Barhoover MA, Nesheim ME. Understanding the Factor Va Cofactor Effect within Prothrombinase. Blood. 110: 2700-2700. DOI: 10.1182/Blood.V110.11.2700.2700  0.806
2007 Hirbawi J, Bukys MA, Barhoover MA, Kalafatis M. The Acidic COOH-Terminal Region of Factor Va Heavy Chain Controls the Rate of Prothrombin Activation by Prothrombinase. Blood. 110: 1745-1745. DOI: 10.1182/Blood.V110.11.1745.1745  0.832
2006 Bukys MA, Kim PY, Nesheim ME, Kalafatis M. A control switch for prothrombinase: characterization of a hirudin-like pentapeptide from the COOH terminus of factor Va heavy chain that regulates the rate and pathway for prothrombin activation. The Journal of Biological Chemistry. 281: 39194-204. PMID 17020886 DOI: 10.1074/Jbc.M604482200  0.754
2006 Bukys MA, Orban T, Kim PY, Beck DO, Nesheim ME, Kalafatis M. The structural integrity of anion binding exosite I of thrombin is required and sufficient for timely cleavage and activation of factor V and factor VIII. The Journal of Biological Chemistry. 281: 18569-80. PMID 16624813 DOI: 10.1074/Jbc.M600752200  0.788
2006 Bukys MA, Simioni P, Smith K, Spiezia L, Kalafatis M. Isolation and Characterization of an Antifactor VIII Antibody from a Patient with Acquired Hemophilia A and a Severe Hemorrhagic Syndrome. Blood. 108: 4073-4073. DOI: 10.1182/Blood.V108.11.4073.4073  0.642
2006 Erdogan E, Bukys MA, Orfeo T, Mann KG, Kalafatis M. Cleavage of Factor Va Heavy Chain at Arg643 by Thrombin Partially Inactivates the Cofactor. Blood. 108: 1703-1703. DOI: 10.1182/Blood.V108.11.1703.1703  0.84
2006 Bukys MA, Kim PY, Nesheim ME, Kalafatis M. Controlling the Pathway for Prothrombin Activation by Prothrombinase. Blood. 108: 1695-1695. DOI: 10.1182/Blood.V108.11.1695.1695  0.78
2005 Bukys MA, Blum MA, Kim PY, Brufatto N, Nesheim ME, Kalafatis M. Incorporation of factor Va into prothrombinase is required for coordinated cleavage of prothrombin by factor Xa. The Journal of Biological Chemistry. 280: 27393-401. PMID 15897196 DOI: 10.1074/Jbc.M503435200  0.765
2005 Bukys MA, Orban T, Kim PY, Nesheim ME, Kalafatis M. Exposure of Anion Binding Exosite I of Thrombin Is Required and Sufficient for Timely Cleavage and Activation of Factor V and Factor VIII. Blood. 106: 1951-1951. DOI: 10.1182/Blood.V106.11.1951.1951  0.781
2005 Hirbawi J, Blum MA, Bukys MA, Orban T, Kalafatis M. Evidence That the COOH-Terminal Region of Factor Va Heavy Chain Is Involved in the Regulation of Prothrombinase Activity. Blood. 106: 1025-1025. DOI: 10.1182/Blood.V106.11.1025.1025  0.807
2004 Beck DO, Bukys MA, Singh LS, Szabo KA, Kalafatis M. The contribution of amino acid region ASP695-TYR698 of factor V to procofactor activation and factor Va function. The Journal of Biological Chemistry. 279: 3084-95. PMID 14559913 DOI: 10.1074/Jbc.M306850200  0.786
2004 Bukys MA, Kim P, Blum MA, Nesheim ME, Kalafatis M. Cofactor Directed Catalysis. Blood. 104: 1715-1715. DOI: 10.1182/Blood.V104.11.1715.1715  0.737
2003 Singh LS, Bukys MA, Beck DO, Kalafatis M. Amino acids Glu323, Tyr324, Glu330, and Val331 of factor Va heavy chain are essential for expression of cofactor activity. The Journal of Biological Chemistry. 278: 28335-45. PMID 12738785 DOI: 10.1074/Jbc.M300233200  0.773
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