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Chih-Chi A. Hu, Ph.D. - Publications

Affiliations: 
2006 New York University, New York, NY, United States 
Area:
Cell Biology, Biochemistry
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Lee AC, Pingali SR, Pinilla-Ibarz JA, Atchison ML, Koumenis C, Argon Y, Thomas-Tikhonenko A, De Trez C, Hu CA, Tang CA. Loss of AID exacerbates the malignant progression of CLL. Leukemia. PMID 36042317 DOI: 10.1038/s41375-022-01663-5  0.363
2021 Choi HJ, Tang CA, Tian L, Wu Y, Sofi MH, Ticer T, Schutt SD, Hu CA, Yu XZ. XBP-1s Promotes B Cell Pathogenicity in Chronic GVHD by Restraining the Activity of Regulated IRE-1α-Dependent Decay. Frontiers in Immunology. 12: 705484. PMID 34659198 DOI: 10.3389/fimmu.2021.705484  0.416
2021 van Anken E, Bakunts A, Hu CA, Janssens S, Sitia R. Molecular Evaluation of Endoplasmic Reticulum Homeostasis Meets Humoral Immunity. Trends in Cell Biology. PMID 33685797 DOI: 10.1016/j.tcb.2021.02.004  0.315
2021 Wu Y, Tang CA, Mealer C, Bastian D, Hanief Sofi M, Tian L, Schutt S, Choi HJ, Ticer T, Zhang M, Sui X, Huang L, Mellor AL, Hu CA, Yu XZ. STING negatively regulates allogeneic T-cell responses by constraining antigen-presenting cell function. Cellular & Molecular Immunology. PMID 33500563 DOI: 10.1038/s41423-020-00611-6  0.315
2020 Shao A, Xu Q, Spalek WT, Cain CF, Kang CW, Tang CA, Del Valle JR, Hu CA. Development of tumor-targeting IRE-1 inhibitors for B cell cancer therapy. Molecular Cancer Therapeutics. PMID 33051362 DOI: 10.1158/1535-7163.MCT-20-0127  0.328
2020 Tang CA, Lee AC, Chang S, Xu Q, Shao A, Lo Y, Spalek WT, Pinilla-Ibarz JA, Del Valle JR, Hu CA. STING regulates BCR signaling in normal and malignant B cells. Cellular & Molecular Immunology. PMID 32999453 DOI: 10.1038/s41423-020-00552-0  0.378
2020 Shrestha N, Liu T, Ji Y, Reinert R, Torres M, Li X, Zhang M, Tang CA, Hu CA, Liu C, Naji A, Liu M, Lin JD, Kersten S, Arvan P, et al. Sel1L-Hrd1 ER-associated degradation maintains β-cell identity via TGFβ signaling. The Journal of Clinical Investigation. PMID 32182217 DOI: 10.1172/Jci134874  0.353
2020 Wu Y, Tang CA, Mealer C, Bastian D, Sofi MH, Tian L, Schutt SD, Choi H, Ticer T, Zhang M, Huang L, Mellor AL, Hu CA, Yu X. Sting Negatively Regulates Allogeneic T-Cell Responses By Constraining Antigen-Presenting Cell Function Blood. 136: 37-38. DOI: 10.1182/BLOOD-2020-139860  0.363
2019 Liao Y, Tham DKL, Liang FX, Chang J, Wei Y, Reddy SP, Sall J, Ren SJ, Chicote JU, Arnold LL, Hu CA, Romih R, Andrade LR, Rindler MJ, Cohen SM, et al. Mitochondrial lipid droplet formation as a detoxification mechanism to sequester and degrade excessive urothelial membranes. Molecular Biology of the Cell. mbcE19050284. PMID 31577526 DOI: 10.1091/Mbc.E19-05-0284  0.458
2019 Tang CA, Valle JRD, Hu CA. Abstract 2661: Targeting endoplasmic reticulum-resident proteins for the treatment of B cell cancer Cancer Research. 79: 2661-2661. DOI: 10.1158/1538-7445.Am2019-2661  0.474
2018 Betts BC, Locke FL, Sagatys EM, Pidala J, Walton K, Menges M, Reff J, Saha A, Djeu JY, Kiluk JV, Lee MC, Kim J, Kang CW, Tang CA, Frieling J, ... ... Hu CA, et al. Inhibition of Human Dendritic Cell ER Stress Response Reduces T Cell Alloreactivity Yet Spares Donor Anti-tumor Immunity. Frontiers in Immunology. 9: 2887. PMID 30574153 DOI: 10.3389/Fimmu.2018.02887  0.442
2018 Bagashev A, Sotillo E, Tang CA, Black KL, Perazzelli J, Seeholzer SH, Argon Y, Barrett DM, Grupp SA, Hu CA, Thomas-Tikhonenko A. CD19 alterations emerging after CD19-directed immunotherapy cause retention of the misfolded protein in the endoplasmic reticulum. Molecular and Cellular Biology. PMID 30104252 DOI: 10.1128/Mcb.00383-18  0.311
2018 De Leo A, Chen HS, Hu CA, Lieberman PM. Correction: Deregulation of KSHV latency conformation by ER-stress and caspase-dependent RAD21-cleavage. Plos Pathogens. 14: e1007027. PMID 29694443 DOI: 10.1371/Journal.Ppat.1007027  0.307
2018 Tang CA, Chang S, Hashimoto A, Chen YJ, Kang CW, Mato AR, Del Valle JR, Gabrilovich D, Hu CA. Secretory IgM exacerbates tumor progression by inducing accumulations of MDSCs in mice. Cancer Immunology Research. PMID 29650518 DOI: 10.1158/2326-6066.Cir-17-0582  0.398
2018 Tang CA, Chang S, Paton AW, Paton JC, Gabrilovich DI, Ploegh HL, Del Valle JR, Hu CA. Phosphorylation of IRE1 at S729 regulates RIDD in B cells and antibody production after immunization. The Journal of Cell Biology. PMID 29511123 DOI: 10.1083/Jcb.201709137  0.425
2018 Schutt SD, Wu Y, Tang CA, Bastian D, Nguyen H, Sofi MH, Zhang M, Liu C, Helke K, Wilson C, Schnapp LM, Del Valle JR, Hu CA, Yu XZ. Inhibition of the IRE-1α/XBP-1 pathway prevents chronic GVHD and preserves the GVL effect in mice. Blood Advances. 2: 414-427. PMID 29483082 DOI: 10.1182/Bloodadvances.2017009068  0.443
2018 Xie H, Tang CA, Song JH, Mancuso A, Valle JRD, Cao J, Xiang Y, Dang CV, Lan R, Sanchez DJ, Keith B, Hu CA, Simon MC. IRE1α RNase-dependent lipid homeostasis promotes survival in Myc-transformed cancers. The Journal of Clinical Investigation. PMID 29381485 DOI: 10.1172/Jci95864  0.381
2018 Tang C, Chang S, Hashimoto A, Chen Y, Kang CW, Mato A, Valle JD, Gabrilovich D, Hu CA. Abstract 4756: Secretory IgM exacerbates tumor progression by inducing accumulations of myeloid-derived suppressor cells in mice Cancer Research. 78: 4756-4756. DOI: 10.1158/1538-7445.Am2018-4756  0.408
2018 Betts BC, Locke FL, Sagatys EM, Pidala JA, Walton K, Menges M, Reff J, Djeu JY, Kiluk JV, Lee MC, Kang CW, List AF, Valle JRD, Hu CA, Anasetti C. Inhibition of Human Dendritic Cell ER Stress Reduces Gvhd Without Impairing Tregs, NK Cells, or Anti-Tumor Ctl Biology of Blood and Marrow Transplantation. 24. DOI: 10.1016/J.Bbmt.2017.12.133  0.413
2017 De Leo A, Chen HS, Hu CA, Lieberman PM. Deregulation of KSHV latency conformation by ER-stress and caspase-dependent RAD21-cleavage. Plos Pathogens. 13: e1006596. PMID 28854249 DOI: 10.1371/Journal.Ppat.1006596  0.43
2017 Tavernier SJ, Osorio F, Vandersarren L, Vetters J, Vanlangenakker N, Van Isterdael G, Vergote K, De Rycke R, Parthoens E, van de Laar L, Iwawaki T, Del Valle JR, Hu CA, Lambrecht BN, Janssens S. Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival. Nature Cell Biology. PMID 28459443 DOI: 10.1038/Ncb3518  0.408
2017 Tang C, Chang S, Paton A, Paton J, Gabrilovich D, Ploegh H, Valle JD, Hu CA. Abstract LB-336: Specific serine phosphorylation of IRE-1 controls enhanced splicing of XBP-1 and regulated IRE-1-dependent decay (RIDD) Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Lb-336  0.431
2016 Zhao C, Brown RS, Tang CA, Hu CA, Schlieker C. Site-specific Proteolysis Mobilizes TorsinA from the Membrane of the Endoplasmic Reticulum in Response to ER Stress and B cell Stimulation. The Journal of Biological Chemistry. PMID 26953341 DOI: 10.1074/Jbc.M115.709337  0.31
2016 Tang CA, Zundell JA, Ranatunga S, Lin C, Nefedova Y, Del Valle JR, Hu CA. Agonist-Mediated Activation of STING Induces Apoptosis in Malignant B Cells. Cancer Research. PMID 26951929 DOI: 10.1158/0008-5472.Can-15-1885  0.496
2016 Schutt SD, Tang CA, Wu Y, Bastian DA, Valle JD, Hu CA, Yu X. Prevention of Chronic Gvhd By Targeting Xbp-1 Genetically or Pharmacologically in Mice Blood. 128: 4541-4541. DOI: 10.1182/Blood.V128.22.4541.4541  0.424
2007 Hu CA, Donald SP, Yu J, Lin WW, Liu Z, Steel G, Obie C, Valle D, Phang JM. Overexpression of proline oxidase induces proline-dependent and mitochondria-mediated apoptosis. Molecular and Cellular Biochemistry. 295: 85-92. PMID 16874462 DOI: 10.1007/S11010-006-9276-6  0.305
2006 Liu Y, Borchert GL, Surazynski A, Hu CA, Phang JM. Proline oxidase activates both intrinsic and extrinsic pathways for apoptosis: The role of ROS/superoxides, NFAT and MEK/ERK signaling Oncogene. 25: 5640-5647. PMID 16619034 DOI: 10.1038/sj.onc.1209564  0.301
2005 Liu Y, Borchert GL, Donald SP, Surazynski A, Hu CA, Weydert CJ, Oberley LW, Phang JM. MnSOD inhibits proline oxidase-induced apoptosis in colorectal cancer cells. Carcinogenesis. 26: 1335-42. PMID 15817612 DOI: 10.1093/Carcin/Bgi083  0.331
2005 Tang CA, Hu CA, Wei C, Wang J. Synergism of Rana catesbeiana ribonuclease and IFN-γ triggers distinct death machineries in different human cancer cells Febs Letters. 579: 265-270. PMID 15620724 DOI: 10.1016/J.Febslet.2004.11.086  0.427
2001 Hu CA, Tang CA, Wang J. Caspase activation in response to cytotoxic Rana catesbeiana ribonuclease in MCF‐7 cells Febs Letters. 503: 65-68. PMID 11513856 DOI: 10.1016/S0014-5793(01)02691-6  0.424
2001 Hu CA, Lee Y, Tang CA, Cheng J, Wang J. Synergistic Cytotoxicity of Rana catesbeiana Ribonuclease and IFN-γ on Hepatoma Cells Biochemical and Biophysical Research Communications. 280: 1229-1236. PMID 11162659 DOI: 10.1006/Bbrc.2001.4272  0.42
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