Year |
Citation |
Score |
2023 |
Wang C, Adam GC, Burlein C, Carroll S, Dankulich W, Diamond T, Grobler J, Heath J, Johnson A, Klein D, Krosky D, Narayan K, Ou Y, Sanders J, Sharma S, et al. Discovery of arylsulfonamides as a novel class of allosteric integrase inhibitors with antiviral activity. Bioorganic & Medicinal Chemistry Letters. 129303. PMID 37146837 DOI: 10.1016/j.bmcl.2023.129303 |
0.355 |
|
2022 |
Diaz E, Adhikary S, Tepper AWJW, Riley D, Ortiz-Meoz R, Krosky D, Buyck C, Lamenca CM, Llaveria J, Fang L, Kalin JH, Klaren VNA, Fahmy S, Shaffer PL, Kirkpatrick R, et al. Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor. Communications Biology. 5: 787. PMID 35931745 DOI: 10.1038/s42003-022-03735-9 |
0.374 |
|
2021 |
Beshore DC, Adam GC, Barnard RJO, Burlein C, Gallicchio SN, Holloway MK, Krosky D, Lemaire W, Myers RW, Patel S, Plotkin MA, Powell DA, Rada V, Cox CD, Coleman PJ, et al. Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor Interaction. Acs Medicinal Chemistry Letters. 12: 540-547. PMID 33854701 DOI: 10.1021/acsmedchemlett.1c00074 |
0.302 |
|
2007 |
Parker JB, Bianchet MA, Krosky DJ, Friedman JI, Amzel LM, Stivers JT. Enzymatic capture of an extrahelical thymine in the search for uracil in DNA. Nature. 449: 433-7. PMID 17704764 DOI: 10.1038/Nature06131 |
0.731 |
|
2006 |
Krosky DJ, Bianchet MA, Seiple L, Chung S, Amzel LM, Stivers JT. Mimicking damaged DNA with a small molecule inhibitor of human UNG2. Nucleic Acids Research. 34: 5872-9. PMID 17062624 DOI: 10.1093/Nar/Gkl747 |
0.635 |
|
2006 |
Cao C, Jiang YL, Krosky DJ, Stivers JT. The catalytic power of uracil DNA glycosylase in the opening of thymine base pairs. Journal of the American Chemical Society. 128: 13034-5. PMID 17017766 DOI: 10.1021/Ja062978N |
0.758 |
|
2006 |
Jiang YL, Chung S, Krosky DJ, Stivers JT. Synthesis and high-throughput evaluation of triskelion uracil libraries for inhibition of human dUTPase and UNG2. Bioorganic & Medicinal Chemistry. 14: 5666-72. PMID 16678429 DOI: 10.1016/J.Bmc.2006.04.022 |
0.784 |
|
2005 |
Jiang YL, Krosky DJ, Seiple L, Stivers JT. Uracil-directed ligand tethering: an efficient strategy for uracil DNA glycosylase (UNG) inhibitor development. Journal of the American Chemical Society. 127: 17412-20. PMID 16332091 DOI: 10.1021/Ja055846N |
0.642 |
|
2005 |
Krosky DJ, Song F, Stivers JT. The origins of high-affinity enzyme binding to an extrahelical DNA base. Biochemistry. 44: 5949-59. PMID 15835884 DOI: 10.1021/Bi050084U |
0.798 |
|
2004 |
Krosky DJ, Schwarz FP, Stivers JT. Linear free energy correlations for enzymatic base flipping: how do damaged base pairs facilitate specific recognition? Biochemistry. 43: 4188-95. PMID 15065862 DOI: 10.1021/Bi036303Y |
0.768 |
|
2002 |
Drohat AC, Kwon K, Krosky DJ, Stivers JT. 3-Methyladenine DNA glycosylase I is an unexpected helix-hairpin-helix superfamily member. Nature Structural Biology. 9: 659-64. PMID 12161745 DOI: 10.1038/Nsb829 |
0.77 |
|
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