Kavitha Balaji, Ph.D. - Related publications

2014 Biological Chemistry 0117 University of California, Los Angeles, Los Angeles, CA 
Cell Biology, Biochemistry
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Tran T, Mitra J, Ha T, Kavran JM. Increasing kinase domain proximity promotes MST2 autophosphorylation during Hippo signaling. The Journal of Biological Chemistry. PMID 32994222 DOI: 10.1074/jbc.RA120.015723   
2020 Gopallawa I, Lee RJ. Targeting the phosphoinositide-3-kinase/protein kinase B pathway in airway innate immunity. World Journal of Biological Chemistry. 11: 30-51. PMID 33024516 DOI: 10.4331/wjbc.v11.i2.30   
2020 Liang Y, Zhang T, Ren L, Jing S, Li Z, Zuo P, Li T, Wang Y, Zhang J, Wei Z. Cucurbitacin IIb induces apoptosis and cell cycle arrest through regulating EGFR/MAPK pathway. Environmental Toxicology and Pharmacology. 103542. PMID 33161110 DOI: 10.1016/j.etap.2020.103542   
2020 Gerosa L, Chidley C, Fröhlich F, Sanchez G, Lim SK, Muhlich J, Chen JY, Vallabhaneni S, Baker GJ, Schapiro D, Atanasova MI, Chylek LA, Shi T, Yi L, Nicora CD, et al. Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells. Cell Systems. PMID 33113355 DOI: 10.1016/j.cels.2020.10.002   
2020 Gillies TE, Pargett M, Silva JM, Teragawa CK, McCormick F, Albeck JG. Oncogenic mutant RAS signaling activity is rescaled by the ERK/MAPK pathway. Molecular Systems Biology. 16: e9518. PMID 33073539 DOI: 10.15252/msb.20209518   
2020 Lee SW, Commisso C. Metabolic regulation of EGFR effector and feedback signaling in pancreatic cancer cells requires K-Ras. Biochemical and Biophysical Research Communications. PMID 32972751 DOI: 10.1016/j.bbrc.2020.09.029   
2020 Gonzalez-Magaldi M, McCabe JM, Cartwright HN, Sun N, Leahy DJ. Conserved Roles for Receptor Tyrosine Kinase Extracellular Regions in Regulating Receptor and Pathway Activity. The Biochemical Journal. PMID 33043983 DOI: 10.1042/BCJ20200702   
2020 Lee KJ, Kim Y, Kim MS, Ju HM, Choi B, Lee H, Jeoung D, Moon KW, Kang D, Choi J, Yook JI, Hahn JH. CD99-PTPN12 Axis Suppresses Actin Cytoskeleton-Mediated Dimerization of Epidermal Growth Factor Receptor. Cancers. 12. PMID 33050232 DOI: 10.3390/cancers12102895   
2020 Dai C, Shen L, Jin W, Lv B, Liu P, Wang X, Yin Y, Fu Y, Liang L, Ma Z, Zhang X, Wang Y, Xu D, Chen Z. Physapubescin B enhances the sensitivity of gastric cancer cells to trametinib by inhibiting the STAT3 signaling pathway. Toxicology and Applied Pharmacology. 115273. PMID 33035574 DOI: 10.1016/j.taap.2020.115273   
2020 Buckles TC, Ohashi Y, Tremel S, McLaughlin SH, Pardon E, Steyaert J, Gordon M, Williams RL, Falke JJ. Regulation of a Class III PI3K Lipid Kinase (VPS34 Complex II) by the Small G Protein Rab5A: Single Molecule Analysis Reveals a Dual Regulatory Mechanism. Biophysical Journal. PMID 33137306 DOI: 10.1016/j.bpj.2020.10.028   
2020 Shapira T, Rankine-Wilson L, Chao JD, Pichler V, Rens C, Pfeifer T, Av-Gay Y. High-Content Screening of Eukaryotic Kinase Inhibitors Identify CHK2 Inhibitor Activity Against . Frontiers in Microbiology. 11: 553962. PMID 33042061 DOI: 10.3389/fmicb.2020.553962   
2020 Hirata Y, Nada Y, Yamada Y, Toyama T, Fukunaga K, Hwang GW, Noguchi T, Matsuzawa A. Elaidic Acid Potentiates Extracellular ATP-Induced Apoptosis via the P2X-ROS-ASK1-p38 Axis in Microglial Cell Lines. Biological & Pharmaceutical Bulletin. 43: 1562-1569. PMID 32999166 DOI: 10.1248/bpb.b20-00409   
2020 Martin AP, Aushev VN, Zalcman G, Camonis JH. The STK38-XPO1 axis, a new actor in physiology and cancer. Cellular and Molecular Life Sciences : Cmls. PMID 33145612 DOI: 10.1007/s00018-020-03690-w   
2020 Gaviraghi M, Rabellino A, Andolfo A, Brand M, Brombin C, Bagnato P, De Feudis G, Raimondi A, Locatelli A, Tosoni D, Mazza D, Gianni L, Tonon G, Yarden Y, Tacchetti C, et al. Direct stimulation of ERBB2 highlights a novel cytostatic signaling pathway driven by the receptor Thr phosphorylation. Scientific Reports. 10: 16906. PMID 33037285 DOI: 10.1038/s41598-020-73835-1   
2020 Pakharukova N, Masoudi A, Pani B, Staus DP, Lefkowitz RJ. Allosteric activation of proto-oncogene kinase Src by GPCR-beta-arrestin complexes. The Journal of Biological Chemistry. PMID 32978252 DOI: 10.1074/jbc.RA120.015400   
2020 Gu J, Qian L, Zhang G, Mahajan NP, Owonikoko TK, Ramalingam SS, Sun SY. Inhibition of ACK1 delays and overcomes acquired resistance of EGFR mutant NSCLC cells to the third generation EGFR inhibitor, osimertinib. Lung Cancer (Amsterdam, Netherlands). 150: 26-35. PMID 33049499 DOI: 10.1016/j.lungcan.2020.09.023   
2020 Soamalala J, Diot S, Pellerano M, Blanquart C, Galibert M, Jullian M, Puget K, Morris MC. Fluorescent peptide biosensor for probing CDK6 activity in lung cancer cell extracts. Chembiochem : a European Journal of Chemical Biology. PMID 33112024 DOI: 10.1002/cbic.202000677   
2020 Tiwari A, Iida M, Kosnopfel C, Abbariki M, Menegakis A, Fehrenbacher B, Maier J, Schaller M, Brucker SY, Wheeler DL, Harari PM, Rothbauer U, Schittek B, Zips D, Toulany M. Blocking Y-Box Binding Protein-1 through Simultaneous Targeting of PI3K and MAPK in Triple Negative Breast Cancers. Cancers. 12. PMID 33003386 DOI: 10.3390/cancers12102795   
2020 Tiwari A, Iida M, Kosnopfel C, Abbariki M, Menegakis A, Fehrenbacher B, Maier J, Schaller M, Brucker SY, Wheeler DL, Harari PM, Rothbauer U, Schittek B, Zips D, Toulany M. Blocking Y-Box Binding Protein-1 through Simultaneous Targeting of PI3K and MAPK in Triple Negative Breast Cancers. Cancers. 12. PMID 33003386 DOI: 10.3390/cancers12102795   
2020 Singh S, Smith MJ. RAS GTPase signalling to alternative effector pathways. Biochemical Society Transactions. 48: 2241-2252. PMID 33125484 DOI: 10.1042/BST20200506   
2020 Silva LP, Frawley D, Assis LJ, Tierney C, Fleming AB, Bayram O, Goldman GH. Putative Membrane Receptors Contribute to Activation and Efficient Signaling of Mitogen-Activated Protein Kinase Cascades during Adaptation of Aspergillus fumigatus to Different Stressors and Carbon Sources. Msphere. 5. PMID 32938702 DOI: 10.1128/mSphere.00818-20   
2020 Tian Y, Zhao L. Metformin induces apoptosis of melanoma B16 cells via PI3K/Akt/mTOR signaling pathways. Journal of B.U.On. : Official Journal of the Balkan Union of Oncology. 25: 2066-2070. PMID 33099954   
2020 Zhang H, Lu S, Xu R, Tang Y, Liu J, Li C, Wei J, Yao R, Zhao X, Wei Q, Ma B. Mechanisms of estradiol-induced EGF-like factor expression and oocyte maturation via G protein-coupled estrogen receptor. Endocrinology. PMID 33068422 DOI: 10.1210/endocr/bqaa190   
2020 Ertosun MG, DİlmaÇ S, Hapİl FZ, TanriÖver G, KÖksoy S, ÖzeŞ ON. Regulation of E2F1 activity via PKA-mediated phosphorylations. Turkish Journal of Biology = Turk Biyoloji Dergisi. 44: 215-229. PMID 33110360 DOI: 10.3906/biy-2003-9   
2020 Asih PR, Prikas E, Stefanoska K, Tan ARP, Ahel HI, Ittner A. Functions of p38 MAP Kinases in the Central Nervous System. Frontiers in Molecular Neuroscience. 13: 570586. PMID 33013322 DOI: 10.3389/fnmol.2020.570586   
2020 Chen H, Libring S, Ruddraraju KV, Miao J, Solorio L, Zhang ZY, Wendt MK. SHP2 is a multifunctional therapeutic target in drug resistant metastatic breast cancer. Oncogene. PMID 33033382 DOI: 10.1038/s41388-020-01488-5   
2020 Lee SW, Commisso C. Rac1 and EGFR cooperate to activate Pak in response to nutrient stress. Biochemical and Biophysical Research Communications. PMID 32972756 DOI: 10.1016/j.bbrc.2020.09.043   
2020 Liu QQ, Zeng XL, Guan YL, Lu JX, Tu K, Liu FY. Verticillin A inhibits colon cancer cell migration and invasion by targeting c-Met. Journal of Zhejiang University. Science. B. 21: 779-795. PMID 33043644 DOI: 10.1631/jzus.B2000190   
2020 Alme EB, Toczyski DP. Redundant targeting of Isr1 by two CDKs in mitotic cells. Current Genetics. PMID 33063175 DOI: 10.1007/s00294-020-01110-x   
2020 Duan Y, Haybaeck J, Yang Z. Therapeutic Potential of PI3K/AKT/mTOR Pathway in Gastrointestinal Stromal Tumors: Rationale and Progress. Cancers. 12. PMID 33066449 DOI: 10.3390/cancers12102972   
2020 Martinez R, Huang W, Samadani R, Mackowiak B, Centola G, Chen L, Conlon IL, Hom K, Kane MA, Fletcher S, Shapiro P. Mechanistic analysis of an ERK2-interacting compound that inhibits mutant-BRAF expressing melanoma cells by inducing oxidative stress. The Journal of Pharmacology and Experimental Therapeutics. PMID 33109619 DOI: 10.1124/jpet.120.000266   
2020 Halkowycz P, Grimshaw CE, Keung W, Tanis P, Proffitt C, Peacock K, de Jong R, Sabat M, Banerjee U, Ermolieff J. Biochemical and Cellular Profile of NIK Inhibitors with Long Residence Times. Slas Discovery : Advancing Life Sciences R & D. 2472555220964450. PMID 33084478 DOI: 10.1177/2472555220964450   
2020 Halkowycz P, Grimshaw CE, Keung W, Tanis P, Proffitt C, Peacock K, de Jong R, Sabat M, Banerjee U, Ermolieff J. Biochemical and Cellular Profile of NIK Inhibitors with Long Residence Times. Slas Discovery : Advancing Life Sciences R & D. 2472555220964450. PMID 33084478 DOI: 10.1177/2472555220964450   
2020 Cho JH, Kim K, Kim SA, Park S, Park BO, Kim JH, Kim SY, Kwon MJ, Han MH, Lee SB, Park BC, Park SG, Kim JH, Kim S. Deubiquitinase OTUD5 is a positive regulator of mTORC1 and mTORC2 signaling pathways. Cell Death and Differentiation. PMID 33110214 DOI: 10.1038/s41418-020-00649-z   
2020 Huang JB, Hsu SP, Pan HY, Chen SD, Chen SF, Lin TK, Liu XP, Li JH, Chen NC, Liou CW, Hsu CY, Chuang HY, Chuang YC. Peroxisome Proliferator-Activated Receptor γ Coactivator 1α Activates Vascular Endothelial Growth Factor That Protects Against Neuronal Cell Death Following Status Epilepticus through PI3K/AKT and MEK/ERK Signaling. International Journal of Molecular Sciences. 21. PMID 33008083 DOI: 10.3390/ijms21197247   
2020 Wang J, Pollard K, Allen AN, Tomar T, Pijnenburg D, Yao Z, Rodriguez FJ, Pratilas CA. Combined inhibition of SHP2 and MEK is effective in models of NF1-deficient malignant peripheral nerve sheath tumors. Cancer Research. PMID 33032988 DOI: 10.1158/0008-5472.CAN-20-1365   
2020 Kumar S, Agrawal S, Maity S, AlRaawi Z, Al-Ameer M. Targeting Drugs Against Fibroblast Growth Factor(s)-Induced Cell Signaling. Current Drug Targets. PMID 33045958 DOI: 10.2174/1389450121999201012201926   
2020 Sharma DK, Bihani SC, Siddiqui MQ, Misra HS, Rajpurohit YS. WD40 domain of RqkA regulates its kinase activity and role in extraordinary radioresistance of . Journal of Biomolecular Structure & Dynamics. 1-14. PMID 32990194 DOI: 10.1080/07391102.2020.1824810   
2020 Saidu NEB, Bonini C, Dickinson A, Grce M, Inngjerdingen M, Koehl U, Toubert A, Zeiser R, Galimberti S. New Approaches for the Treatment of Chronic Graft-Versus-Host Disease: Current Status and Future Directions. Frontiers in Immunology. 11: 578314. PMID 33162993 DOI: 10.3389/fimmu.2020.578314   
2020 Kumar S, Singh SK, Rana B, Rana A. The regulatory function of mixed lineage kinase 3 in tumor and host immunity. Pharmacology & Therapeutics. 107704. PMID 33045253 DOI: 10.1016/j.pharmthera.2020.107704   
2020 Sopjani M, Morina R, Uka V, Xuan NT, Dërmaku-Sopjani M. JAK2-mediated intracellular signaling. Current Molecular Medicine. PMID 33059575 DOI: 10.2174/1566524020666201015144702   
2020 Jeong H, Park S, Kim SY, Cho SH, Jeong MS, Kim SR, Seo JB, Kim SH, Kim KN. 1-Cinnamoyltrichilinin from Causes Apoptosis through the p38 MAPK Pathway in HL-60 Human Leukemia Cells. International Journal of Molecular Sciences. 21. PMID 33053881 DOI: 10.3390/ijms21207506   
2020 Wang Z, Gou X. Receptor-Like Protein Kinases Function Upstream of MAPKs in Regulating Plant Development. International Journal of Molecular Sciences. 21. PMID 33076465 DOI: 10.3390/ijms21207638   
2020 Li L, Xiang Y, Zeng Y, Xiao B, Yu W, Duan C, Xia X, Zhang T, Zeng Y, Liu Y, Dai R. GSK‑3β inhibition promotes doxorubicin‑induced apoptosis in human cholangiocarcinoma cells via FAK/AKT inhibition. Molecular Medicine Reports. 22: 4432-4441. PMID 33000181 DOI: 10.3892/mmr.2020.11502   
2020 Semesta KM, Tian R, Kampmann M, von Zastrow M, Tsvetanova NG. A high-throughput CRISPR interference screen for dissecting functional regulators of GPCR/cAMP signaling. Plos Genetics. 16: e1009103. PMID 33052901 DOI: 10.1371/journal.pgen.1009103   
2020 Xia C, Gong Y, Chong K, Xu Y. Phosphatase OsPP2C27 directly dephosphorylates OsMAPK3 and OsbHLH002 to negatively regulate cold tolerance in rice. Plant, Cell & Environment. PMID 33150964 DOI: 10.1111/pce.13938   
2020 Song J, Bai J, Wang S, Liu L, Zhao Z. [Effects of Quercetin on Autophagy and Phosphatidylinositol 3-kinase/Protein Kinase B/Mammalian Target of Rapamycin Signaling Pathway in Human Prostate Cancer PC-3 Cells]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae. 42: 578-584. PMID 33131510 DOI: 10.3881/j.issn.1000-503X.12361   
2020 Junaid M, Akter Y, Afrose SS, Tania M, Khan MA. Biological role of AKT, and regulation of AKT signaling pathway by thymoquinone: perspectives in cancer therapeutics. Mini Reviews in Medicinal Chemistry. PMID 33019927 DOI: 10.2174/1389557520666201005143818   
2020 Huang W, Wang S, Zhang Z, Zhang C, Zeng S, Liang M, Shen Z, Liu X. HZ-A-005, a potent, selective, and covalent Bruton's tyrosine kinase inhibitor in preclinical development. Bioorganic Chemistry. 105: 104377. PMID 33091668 DOI: 10.1016/j.bioorg.2020.104377   
2020 Yang C, Sheng Y, Shi X, Liu Y, He Y, Du Y, Zhang G, Gao F. CD44/HA signaling mediates acquired resistance to a PI3Kα inhibitor. Cell Death & Disease. 11: 831. PMID 33024087 DOI: 10.1038/s41419-020-03037-0