Haipeng Shao, Ph.D. - Related publications

Affiliations: 
2000 University of Kentucky, Lexington, KY 
Area:
Molecular Biology
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Cho JH, Kim K, Kim SA, Park S, Park BO, Kim JH, Kim SY, Kwon MJ, Han MH, Lee SB, Park BC, Park SG, Kim JH, Kim S. Deubiquitinase OTUD5 is a positive regulator of mTORC1 and mTORC2 signaling pathways. Cell Death and Differentiation. PMID 33110214 DOI: 10.1038/s41418-020-00649-z   
2020 Tran T, Mitra J, Ha T, Kavran JM. Increasing kinase domain proximity promotes MST2 autophosphorylation during Hippo signaling. The Journal of Biological Chemistry. PMID 32994222 DOI: 10.1074/jbc.RA120.015723   
2020 Makino T, Mizawa M, Yoshihisa Y, Yamamoto S, Tabuchi Y, Miyai M, Hibino T, Sasahara M, Shimizu T. Trichohyalin-like 1 protein plays a crucial role in proliferation and anti-apoptosis of normal human keratinocytes and squamous cell carcinoma cells. Cell Death Discovery. 6: 109. PMID 33133644 DOI: 10.1038/s41420-020-00344-5   
2020 Song P, Song B, Liu J, Wang X, Nan X, Wang J. Blockage of PAK1 alleviates the proliferation and invasion of NSCLC cells via inhibiting ERK and AKT signaling activity. Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. PMID 32974862 DOI: 10.1007/s12094-020-02486-5   
2020 Agarwal S, Rath PP, Anand G, Gourinath S. Uncovering the Cyclic AMP Signaling Pathway of the Protozoan Parasite and Understanding Its Role in Phagocytosis. Frontiers in Cellular and Infection Microbiology. 10: 566726. PMID 33102254 DOI: 10.3389/fcimb.2020.566726   
2020 Dai C, Shen L, Jin W, Lv B, Liu P, Wang X, Yin Y, Fu Y, Liang L, Ma Z, Zhang X, Wang Y, Xu D, Chen Z. Physapubescin B enhances the sensitivity of gastric cancer cells to trametinib by inhibiting the STAT3 signaling pathway. Toxicology and Applied Pharmacology. 115273. PMID 33035574 DOI: 10.1016/j.taap.2020.115273   
2020 Ren Y, Song X, Tan L, Guo C, Wang M, Liu H, Cao Z, Li Y, Peng C. A Review of the Pharmacological Properties of Psoralen. Frontiers in Pharmacology. 11: 571535. PMID 33013413 DOI: 10.3389/fphar.2020.571535   
2020 Jeong H, Park S, Kim SY, Cho SH, Jeong MS, Kim SR, Seo JB, Kim SH, Kim KN. 1-Cinnamoyltrichilinin from Causes Apoptosis through the p38 MAPK Pathway in HL-60 Human Leukemia Cells. International Journal of Molecular Sciences. 21. PMID 33053881 DOI: 10.3390/ijms21207506   
2020 Liu R, Chen Y, Liu G, Li C, Song Y, Cao Z, Li W, Hu J, Lu C, Liu Y. PI3K/AKT pathway as a key link modulates the multidrug resistance of cancers. Cell Death & Disease. 11: 797. PMID 32973135 DOI: 10.1038/s41419-020-02998-6   
2020 Singh S, Smith MJ. RAS GTPase signalling to alternative effector pathways. Biochemical Society Transactions. 48: 2241-2252. PMID 33125484 DOI: 10.1042/BST20200506   
2020 Gillies TE, Pargett M, Silva JM, Teragawa CK, McCormick F, Albeck JG. Oncogenic mutant RAS signaling activity is rescaled by the ERK/MAPK pathway. Molecular Systems Biology. 16: e9518. PMID 33073539 DOI: 10.15252/msb.20209518   
2020 Dhanaraman T, Singh S, Killoran RC, Singh A, Xu X, Shifman JM, Smith MJ. RASSF effectors couple diverse RAS subfamily GTPases to the Hippo pathway. Science Signaling. 13. PMID 33051258 DOI: 10.1126/scisignal.abb4778   
2020 Choi H, Roh J. LH-induced Transcriptional Regulation of Expression in Granulosa Cells Occurs via the cAMP/PKA Pathway and Requires a Putative Sp1 Binding Site. International Journal of Molecular Sciences. 21. PMID 33036290 DOI: 10.3390/ijms21197385   
2020 Felgueiras J, Jerónimo C, Fardilha M. Protein phosphatase 1 in tumorigenesis: is it worth a closer look? Biochimica Et Biophysica Acta. Reviews On Cancer. 1874: 188433. PMID 32956763 DOI: 10.1016/j.bbcan.2020.188433   
2020 Tian Y, Zhao L. Metformin induces apoptosis of melanoma B16 cells via PI3K/Akt/mTOR signaling pathways. Journal of B.U.On. : Official Journal of the Balkan Union of Oncology. 25: 2066-2070. PMID 33099954   
2020 Kim PR, Zhang S, Rahmat MB, Koh CG. Partners in crime: POPX2 phosphatase and its interacting proteins in cancer. Cell Death & Disease. 11: 840. PMID 33037179 DOI: 10.1038/s41419-020-03061-0   
2020 Liang Y, Zhang T, Ren L, Jing S, Li Z, Zuo P, Li T, Wang Y, Zhang J, Wei Z. Cucurbitacin IIb induces apoptosis and cell cycle arrest through regulating EGFR/MAPK pathway. Environmental Toxicology and Pharmacology. 103542. PMID 33161110 DOI: 10.1016/j.etap.2020.103542   
2020 Takeuchi T, Lin YT, Fekaris N, Umen JG, Sears BB, Benning C. Modulation of CHT7 complexes during light/dark- and nitrogen-mediated life-cycle transitions of Chlamydomonas. Plant Physiology. PMID 33004613 DOI: 10.1104/pp.20.00864   
2020 Zhang H, Lu S, Xu R, Tang Y, Liu J, Li C, Wei J, Yao R, Zhao X, Wei Q, Ma B. Mechanisms of estradiol-induced EGF-like factor expression and oocyte maturation via G protein-coupled estrogen receptor. Endocrinology. PMID 33068422 DOI: 10.1210/endocr/bqaa190   
2020 Abdel Aziz MH, Fan Y, Liu L, Moasser M, Fu H, Jura N, Arkin MR. Expression and Purification of Active Human Kinases Using Pichia pastoris as A General-Purpose Host. Protein Expression and Purification. 105780. PMID 33115654 DOI: 10.1016/j.pep.2020.105780   
2020 Kumar S, Agrawal S, Maity S, AlRaawi Z, Al-Ameer M. Targeting Drugs Against Fibroblast Growth Factor(s)-Induced Cell Signaling. Current Drug Targets. PMID 33045958 DOI: 10.2174/1389450121999201012201926   
2020 Zhang JF, Liu B, Hong I, Mo A, Roth RH, Tenner B, Lin W, Zhang JZ, Molina RS, Drobizhev M, Hughes TE, Tian L, Huganir RL, Mehta S, Zhang J. An ultrasensitive biosensor for high-resolution kinase activity imaging in awake mice. Nature Chemical Biology. PMID 32989297 DOI: 10.1038/s41589-020-00660-y   
2020 Martinez R, Huang W, Samadani R, Mackowiak B, Centola G, Chen L, Conlon IL, Hom K, Kane MA, Fletcher S, Shapiro P. Mechanistic analysis of an ERK2-interacting compound that inhibits mutant-BRAF expressing melanoma cells by inducing oxidative stress. The Journal of Pharmacology and Experimental Therapeutics. PMID 33109619 DOI: 10.1124/jpet.120.000266   
2020 Huang JB, Hsu SP, Pan HY, Chen SD, Chen SF, Lin TK, Liu XP, Li JH, Chen NC, Liou CW, Hsu CY, Chuang HY, Chuang YC. Peroxisome Proliferator-Activated Receptor γ Coactivator 1α Activates Vascular Endothelial Growth Factor That Protects Against Neuronal Cell Death Following Status Epilepticus through PI3K/AKT and MEK/ERK Signaling. International Journal of Molecular Sciences. 21. PMID 33008083 DOI: 10.3390/ijms21197247   
2020 Chen L, Chen Y, Zhang C, Jiao B, Liang S, Tan Q, Chai H, Yu W, Qian Y, Yang H, Yao W, Yu J, Luo Y, Plewe M, Wang J, et al. Discovery of First-In-Class Potent and Selective Tropomyosin Receptor Kinase Degraders. Journal of Medicinal Chemistry. PMID 33058680 DOI: 10.1021/acs.jmedchem.0c01342   
2020 Huang J, Feng W, Li S, Tang H, Qin S, Li W, Gong Y, Fang Y, Liu Y, Wang S, Guo Y, Xu Z, Shen Q. Berberine Exerts Anti-cancer Activity by Modulating Adenosine Monophosphate-Activated Protein Kinase (AMPK) and the Phosphatidylinositol 3-Kinase/Protein Kinase B (PI3K/AKT) Signaling Pathways. Current Pharmaceutical Design. PMID 32988344 DOI: 10.2174/1381612826666200928155728   
2020 Ertosun MG, DİlmaÇ S, Hapİl FZ, TanriÖver G, KÖksoy S, ÖzeŞ ON. Regulation of E2F1 activity via PKA-mediated phosphorylations. Turkish Journal of Biology = Turk Biyoloji Dergisi. 44: 215-229. PMID 33110360 DOI: 10.3906/biy-2003-9   
2020 Song J, Bai J, Wang S, Liu L, Zhao Z. [Effects of Quercetin on Autophagy and Phosphatidylinositol 3-kinase/Protein Kinase B/Mammalian Target of Rapamycin Signaling Pathway in Human Prostate Cancer PC-3 Cells]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae. 42: 578-584. PMID 33131510 DOI: 10.3881/j.issn.1000-503X.12361   
2020 An N, Chen Y, Xing Y, Wu H, Gao X, Chen H, Song K, Li Y, Li X, Yang F, Pan X, He X, Wang X, Li Y, Gao Y, et al. Cardiac CaMKII and Wenxin Keli Prevents Ang II-Induced Cardiomyocyte Hypertrophy by Modulating CnA-NFATc4 and Inflammatory Signaling Pathways in H9c2 Cells. Evidence-Based Complementary and Alternative Medicine : Ecam. 2020: 9502651. PMID 33149757 DOI: 10.1155/2020/9502651   
2020 Li Y, Shi J, Yang J, Ge S, Zhang J, Jia R, Fan X. Uveal melanoma: progress in molecular biology and therapeutics. Therapeutic Advances in Medical Oncology. 12: 1758835920965852. PMID 33149769 DOI: 10.1177/1758835920965852   
2020 Xia C, Gong Y, Chong K, Xu Y. Phosphatase OsPP2C27 directly dephosphorylates OsMAPK3 and OsbHLH002 to negatively regulate cold tolerance in rice. Plant, Cell & Environment. PMID 33150964 DOI: 10.1111/pce.13938   
2020 Baffi TR, Katsenelson KC, Newton AC. PHLPPing the Script: Emerging Roles of PHLPP Phosphatases in Cell Signaling. Annual Review of Pharmacology and Toxicology. PMID 32997603 DOI: 10.1146/annurev-pharmtox-031820-122108   
2020 Peng Q, Alqahtani S, Nasrullah MZA, Shen J. Functional evidence for biased inhibition of G protein signaling by YM-254890 in human coronary artery endothelial cells. European Journal of Pharmacology. 173706. PMID 33152337 DOI: 10.1016/j.ejphar.2020.173706   
2020 Kumar S, Singh SK, Rana B, Rana A. The regulatory function of mixed lineage kinase 3 in tumor and host immunity. Pharmacology & Therapeutics. 107704. PMID 33045253 DOI: 10.1016/j.pharmthera.2020.107704   
2020 Qiao G, Bi K, Liu J, Cao S, Liu M, Pešić M, Lin X. Protein kinases as targets for developing anticancer agents from marine organisms. Biochimica Et Biophysica Acta. General Subjects. 129759. PMID 33038451 DOI: 10.1016/j.bbagen.2020.129759   
2020 Fang CY, Lai TC, Hsiao M, Chang YC. The Diverse Roles of TAO Kinases in Health and Diseases. International Journal of Molecular Sciences. 21. PMID 33050415 DOI: 10.3390/ijms21207463   
2020 Kang SJ, Lee JW, Song J, Park J, Choi J, Suh KH, Min KH. Synthesis and biological activity of 2-cyanoacrylamide derivatives tethered to imidazopyridine as TAK1 inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry. 35: 1928-1936. PMID 33086897 DOI: 10.1080/14756366.2020.1833876   
2020 Qi Z, Yan F, Chen D, Xing W, Li Q, Zeng W, Bi B, Xie J. Identification of prognostic biomarkers and correlations with immune infiltrates among cGAS-STING in hepatocellular carcinoma. Bioscience Reports. PMID 33006365 DOI: 10.1042/BSR20202603   
2020 Kim MJ, Kang YJ, Sung B, Jang JY, Ahn YR, Oh HJ, Choi H, Choi I, Im E, Moon HR, Chung HY, Kim ND. Novel SIRT Inhibitor, MHY2256, Induces Cell Cycle Arrest, Apoptosis, and Autophagic Cell Death in HCT116 Human Colorectal Cancer Cells. Biomolecules & Therapeutics. PMID 33073770 DOI: 10.4062/biomolther.2020.153   
2020 Tiwari A, Iida M, Kosnopfel C, Abbariki M, Menegakis A, Fehrenbacher B, Maier J, Schaller M, Brucker SY, Wheeler DL, Harari PM, Rothbauer U, Schittek B, Zips D, Toulany M. Blocking Y-Box Binding Protein-1 through Simultaneous Targeting of PI3K and MAPK in Triple Negative Breast Cancers. Cancers. 12. PMID 33003386 DOI: 10.3390/cancers12102795   
2020 Tiwari A, Iida M, Kosnopfel C, Abbariki M, Menegakis A, Fehrenbacher B, Maier J, Schaller M, Brucker SY, Wheeler DL, Harari PM, Rothbauer U, Schittek B, Zips D, Toulany M. Blocking Y-Box Binding Protein-1 through Simultaneous Targeting of PI3K and MAPK in Triple Negative Breast Cancers. Cancers. 12. PMID 33003386 DOI: 10.3390/cancers12102795   
2020 Ye X, Vogt MS, van der Does C, Bildl W, Schulte U, Essen LO, Albers SV. The Phosphatase PP2A Interacts With ArnA and ArnB to Regulate the Oligomeric State and the Stability of the ArnA/B Complex. Frontiers in Microbiology. 11: 1849. PMID 32973695 DOI: 10.3389/fmicb.2020.01849   
2020 Tetenborg S, Wang HY, Nemitz L, Depping A, Espejo AB, Aseervatham J, Bedford MT, Janssen-Bienhold U, O'Brien J, Dedek K. Phosphorylation of Connexin36 near the C-terminus switches binding affinities for PDZ-domain and 14-3-3 proteins in vitro. Scientific Reports. 10: 18378. PMID 33110101 DOI: 10.1038/s41598-020-75375-0   
2020 Wang J, Pollard K, Allen AN, Tomar T, Pijnenburg D, Yao Z, Rodriguez FJ, Pratilas CA. Combined inhibition of SHP2 and MEK is effective in models of NF1-deficient malignant peripheral nerve sheath tumors. Cancer Research. PMID 33032988 DOI: 10.1158/0008-5472.CAN-20-1365   
2020 Yun MW, Kim K, Park JY, Chung KY. Conformational Dynamics Analysis of MEK1 Using Hydrogen/Deuterium Exchange Mass Spectrometry. Protein and Peptide Letters. PMID 33143608 DOI: 10.2174/0929866527666201103152534   
2020 Neuber C, Tröster A, Löser R, Belter B, Schwalbe H, Pietzsch J. The Pyrazolo[3,4-]pyrimidine-Based Kinase Inhibitor NVP-BHG712: Effects of Regioisomers on Tumor Growth, Perfusion, and Hypoxia in EphB4-Positive A375 Melanoma Xenografts. Molecules (Basel, Switzerland). 25. PMID 33153234 DOI: 10.3390/molecules25215115   
2020 Yang Y, Zhu X, Jia X, Hou W, Zhou G, Ma Z, Yu B, Pi Y, Zhang X, Wang J, Wang G. Phosphorylation of Msx1 promotes cell proliferation through the Fgf9/18-MAPK signaling pathway during embryonic limb development. Nucleic Acids Research. PMID 33080014 DOI: 10.1093/nar/gkaa905   
2020 Velázquez D, Albacar M, Zhang C, Calafí C, López-Malo M, Torres-Torronteras J, Martí R, Kovalchuk SI, Pinson B, Jensen ON, Daignan-Fornier B, Casamayor A, Ariño J. Yeast Ppz1 protein phosphatase toxicity involves the alteration of multiple cellular targets. Scientific Reports. 10: 15613. PMID 32973189 DOI: 10.1038/s41598-020-72391-y   
2020 Velázquez D, Albacar M, Zhang C, Calafí C, López-Malo M, Torres-Torronteras J, Martí R, Kovalchuk SI, Pinson B, Jensen ON, Daignan-Fornier B, Casamayor A, Ariño J. Yeast Ppz1 protein phosphatase toxicity involves the alteration of multiple cellular targets. Scientific Reports. 10: 15613. PMID 32973189 DOI: 10.1038/s41598-020-72391-y   
2020 Gaviraghi M, Rabellino A, Andolfo A, Brand M, Brombin C, Bagnato P, De Feudis G, Raimondi A, Locatelli A, Tosoni D, Mazza D, Gianni L, Tonon G, Yarden Y, Tacchetti C, et al. Direct stimulation of ERBB2 highlights a novel cytostatic signaling pathway driven by the receptor Thr phosphorylation. Scientific Reports. 10: 16906. PMID 33037285 DOI: 10.1038/s41598-020-73835-1