Year |
Citation |
Score |
2023 |
Egli M, Schlegel MK, Manoharan M. Acyclic (S)-Glycol Nucleic Acid (S-GNA) Modification of siRNAs Improves the Safety of RNAi Therapeutics While Maintaining Potency. Rna (New York, N.Y.). PMID 36725319 DOI: 10.1261/rna.079526.122 |
0.354 |
|
2017 |
Schlegel MK, Foster DJ, Kel'in AV, Zlatev I, Bisbe A, Jayaraman M, Lackey JG, Rajeev KG, Charisse K, Harp J, Pallan PS, Maier MA, Egli M, Manoharan M. Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA. Journal of the American Chemical Society. PMID 28570818 DOI: 10.1021/Jacs.7B02694 |
0.424 |
|
2017 |
Hahm HS, Schlegel MK, Hurevich M, Eller S, Schuhmacher F, Hofmann J, Pagel K, Seeberger PH. Automated glycan assembly using the Glyconeer 2.1 synthesizer. Proceedings of the National Academy of Sciences of the United States of America. PMID 28396442 DOI: 10.1073/Pnas.1700141114 |
0.331 |
|
2014 |
Yu H, Schlegel MK, McLaughlin LW. The synthesis and structural characterization of both diastereomers of 5′-(hydroxymethyl)-6,5′-cyclo-2′,5′-dideoxyuridine cyclonucleosides Rsc Advances. 4: 32588-32593. DOI: 10.1039/C4Ra04784B |
0.379 |
|
2013 |
Yueh H, Pal A, Chang K, Schlegel MK, McLaughlin LW. Synthesis and NMR assignment of the two diastereomers of 8,6′-Cyclo-2′,6′-Dideoxyadenosine Nucleosides, Nucleotides and Nucleic Acids. 32: 320-332. PMID 23638925 DOI: 10.1080/15257770.2013.778997 |
0.324 |
|
2013 |
Doknic D, Abramo M, Sutkeviciute I, Reinhardt A, Guzzi C, Schlegel MK, Potenza D, Nieto PM, Fieschi F, Seeberger PH, Bernardi A. Synthesis and characterization of linker-armed fucose-based glycomimetics European Journal of Organic Chemistry. 5303-5314. DOI: 10.1002/Ejoc.201300236 |
0.344 |
|
2011 |
Schlegel MK, Hütter J, Eriksson M, Lepenies B, Seeberger PH. Defined presentation of carbohydrates on a duplex DNA scaffold. Chembiochem : a European Journal of Chemical Biology. 12: 2791-800. PMID 22052782 DOI: 10.1002/Cbic.201100511 |
0.395 |
|
2011 |
Johnson AT, Schlegel MK, Meggers E, Essen LO, Wiest O. On the structure and dynamics of duplex GNA. The Journal of Organic Chemistry. 76: 7964-74. PMID 21838272 DOI: 10.1021/Jo201469B |
0.575 |
|
2010 |
Schlegel MK, Essen LO, Meggers E. Atomic resolution duplex structure of the simplified nucleic acid GNA. Chemical Communications (Cambridge, England). 46: 1094-6. PMID 20126724 DOI: 10.1039/B916851F |
0.554 |
|
2009 |
Schlegel MK, Meggers E. Improved phosphoramidite building blocks for the synthesis of the simplified nucleic acid GNA. The Journal of Organic Chemistry. 74: 4615-8. PMID 19441799 DOI: 10.1021/Jo900365A |
0.536 |
|
2009 |
Schlegel MK, Zhang L, Pagano N, Meggers E. Metal-mediated base pairing within the simplified nucleic acid GNA. Organic & Biomolecular Chemistry. 7: 476-82. PMID 19156312 DOI: 10.1039/B816142A |
0.593 |
|
2009 |
Schlegel MK, Xie X, Zhang L, Meggers E. Insight into the high duplex stability of the simplified nucleic acid GNA. Angewandte Chemie (International Ed. in English). 48: 960-3. PMID 19130516 DOI: 10.1002/Anie.200803472 |
0.554 |
|
2008 |
Schlegel MK, Essen LO, Meggers E. Duplex structure of a minimal nucleic acid. Journal of the American Chemical Society. 130: 8158-9. PMID 18529005 DOI: 10.1021/Ja802788G |
0.621 |
|
2007 |
Schlegel MK, Peritz AE, Kittigowittana K, Zhang L, Meggers E. Duplex formation of the simplified nucleic acid GNA. Chembiochem : a European Journal of Chemical Biology. 8: 927-32. PMID 17465439 DOI: 10.1002/Cbic.200600435 |
0.58 |
|
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