Bianca M. Liederer, Ph.D. - Publications

2005 University of Kansas, Lawrence, KS, United States 
Pharmaceutical Chemistry, Pharmacy

35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Zak M, Yuen PW, Liu X, Patel S, Sampath D, Oeh J, Liederer BM, Wang W, O'Brien T, Xiao Y, Skelton N, Hua R, Sodhi J, Wang Y, Zhang L, et al. Minimizing CYP2C9 Inhibition of Exposed-Pyridine NAMPT (Nicotinamide Phosphoribosyltransferase) Inhibitors. Journal of Medicinal Chemistry. PMID 27541271 DOI: 10.1021/Acs.Jmedchem.6B00697  1
2016 Labadie SS, Dragovich PS, Cummings RT, Deshmukh G, Gustafson A, Han N, Harmange JC, Kiefer JR, Li Y, Liang J, Liederer BM, Liu Y, Manieri W, Mao W, Murray L, et al. Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 27499454 DOI: 10.1016/J.Bmcl.2016.07.070  1
2016 Liang J, Zhang B, Labadie S, Ortwine DF, Vinogradova M, Kiefer JR, Gehling VS, Harmange JC, Cummings R, Lai T, Liao J, Zheng X, Liu Y, Gustafson A, Van der Porten E, ... ... Liederer BM, et al. Lead optimization of a pyrazolo[1,5-a]pyrimidin-7(4H)-one scaffold to identify potent, selective and orally bioavailable KDM5 inhibitors suitable for in vivo biological studies. Bioorganic & Medicinal Chemistry Letters. PMID 27406798 DOI: 10.1016/J.Bmcl.2016.06.078  1
2016 Volgraf M, Sellers BD, Jiang Y, Wu G, Ly CQ, Villemure E, Pastor RM, Yuen PW, Lu A, Luo X, Liu M, Zhang S, Sun L, Fu Y, Lupardus PJ, ... ... Liederer BM, et al. Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design. Journal of Medicinal Chemistry. PMID 26919761 DOI: 10.1021/Acs.Jmedchem.5B02010  1
2015 Deshmukh G, Sun K, Liederer BM, Ding X, Liu X. Use of cassette dosing to enhance the throughput of rat brain microdialysis studies. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 1123-8. PMID 25943358 DOI: 10.1124/Dmd.115.064204  1
2015 Schuck E, Bohnert T, Chakravarty A, Damian-Iordache V, Gibson C, Hsu CP, Heimbach T, Krishnatry AS, Liederer BM, Lin J, Maurer T, Mettetal JT, Mudra DR, Nijsen MJ, Raybon J, et al. Preclinical pharmacokinetic/pharmacodynamic modeling and simulation in the pharmaceutical industry: an IQ consortium survey examining the current landscape. The Aaps Journal. 17: 462-73. PMID 25630504 DOI: 10.1208/S12248-014-9716-2  1
2015 Poulin P, Chen YH, Ding X, Gould SE, Hop CE, Messick K, Oeh J, Liederer BM. Prediction of drug distribution in subcutaneous xenografts of human tumor cell lines and healthy tissues in mouse: application of the tissue composition-based model to antineoplastic drugs. Journal of Pharmaceutical Sciences. 104: 1508-21. PMID 25615572 DOI: 10.1002/Jps.24336  1
2015 Zak M, Liederer BM, Sampath D, Yuen PW, Bair KW, Baumeister T, Buckmelter AJ, Clodfelter KH, Cheng E, Crocker L, Fu B, Han B, Li G, Ho YC, Lin J, et al. Identification of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with no evidence of CYP3A4 time-dependent inhibition and improved aqueous solubility. Bioorganic & Medicinal Chemistry Letters. 25: 529-41. PMID 25556090 DOI: 10.1016/J.Bmcl.2014.12.026  1
2015 Zabka TS, Singh J, Dhawan P, Liederer BM, Oeh J, Kauss MA, Xiao Y, Zak M, Lin T, McCray B, La N, Nguyen T, Beyer J, Farman C, Uppal H, et al. Retinal toxicity, in vivo and in vitro, associated with inhibition of nicotinamide phosphoribosyltransferase. Toxicological Sciences : An Official Journal of the Society of Toxicology. 144: 163-72. PMID 25505128 DOI: 10.1093/Toxsci/Kfu268  1
2014 Liang X, Yang L, Qin AR, Ly J, Liederer BM, Messick K, Ma S, Zak M, Dragovich PS, Dean BJ, Hop CE, Deng Y. Measuring NAD(+) levels in mouse blood and tissue samples via a surrogate matrix approach using LC-MS/MS. Bioanalysis. 6: 1445-57. PMID 25046046 DOI: 10.4155/Bio.14.8  1
2014 Giannetti AM, Zheng X, Skelton NJ, Wang W, Bravo BJ, Bair KW, Baumeister T, Cheng E, Crocker L, Feng Y, Gunzner-Toste J, Ho YC, Hua R, Liederer BM, Liu Y, et al. Fragment-based identification of amides derived from trans-2-(pyridin-3-yl)cyclopropanecarboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). Journal of Medicinal Chemistry. 57: 770-92. PMID 24405419 DOI: 10.1021/Jm4015108  1
2013 O'Brien T, Oeh J, Xiao Y, Liang X, Vanderbilt A, Qin A, Yang L, Lee LB, Ly J, Cosino E, LaCap JA, Ogasawara A, Williams S, Nannini M, Liederer BM, et al. Supplementation of nicotinic acid with NAMPT inhibitors results in loss of in vivo efficacy in NAPRT1-deficient tumor models. Neoplasia (New York, N.Y.). 15: 1314-29. PMID 24403854 DOI: 10.1593/Neo.131718  1
2013 Xiao Y, Elkins K, Durieux JK, Lee L, Oeh J, Yang LX, Liang X, DelNagro C, Tremayne J, Kwong M, Liederer BM, Jackson PK, Belmont LD, Sampath D, O'Brien T. Dependence of tumor cell lines and patient-derived tumors on the NAD salvage pathway renders them sensitive to NAMPT inhibition with GNE-618. Neoplasia (New York, N.Y.). 15: 1151-60. PMID 24204194 DOI: 10.1593/Neo.131304  1
2013 Zheng X, Bair KW, Bauer P, Baumeister T, Bowman KK, Buckmelter AJ, Caligiuri M, Clodfelter KH, Feng Y, Han B, Ho YC, Kley N, Li H, Liang X, Liederer BM, et al. Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). Bioorganic & Medicinal Chemistry Letters. 23: 5488-97. PMID 24021463 DOI: 10.1016/J.Bmcl.2013.08.074  1
2013 Dragovich PS, Bair KW, Baumeister T, Ho YC, Liederer BM, Liu X, Liu Y, O'Brien T, Oeh J, Sampath D, Skelton N, Wang L, Wang W, Wu H, Xiao Y, et al. Identification of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-derived ureas as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). Bioorganic & Medicinal Chemistry Letters. 23: 4875-85. PMID 23899614 DOI: 10.1016/J.Bmcl.2013.06.090  1
2013 Poulin P, Dambach DM, Hartley DH, Ford K, Theil FP, Harstad E, Halladay J, Choo E, Boggs J, Liederer BM, Dean B, Diaz D. An algorithm for evaluating potential tissue drug distribution in toxicology studies from readily available pharmacokinetic parameters. Journal of Pharmaceutical Sciences. 102: 3816-29. PMID 23878104 DOI: 10.1002/Jps.23670  1
2013 Zheng X, Bauer P, Baumeister T, Buckmelter AJ, Caligiuri M, Clodfelter KH, Han B, Ho YC, Kley N, Lin J, Reynolds DJ, Sharma G, Smith CC, Wang Z, Dragovich PS, ... ... Liederer BM, et al. Structure-based discovery of novel amide-containing nicotinamide phosphoribosyltransferase (nampt) inhibitors. Journal of Medicinal Chemistry. 56: 6413-33. PMID 23859118 DOI: 10.1021/Jm4008664  1
2013 Zou P, Liu X, Wong S, Feng MR, Liederer BM. Comparison of in vitro-in vivo extrapolation of biliary clearance using an empirical scaling factor versus transport-based scaling factors in sandwich-cultured rat hepatocytes. Journal of Pharmaceutical Sciences. 102: 2837-50. PMID 23712819 DOI: 10.1002/Jps.23620  1
2013 Gunzner-Toste J, Zhao G, Bauer P, Baumeister T, Buckmelter AJ, Caligiuri M, Clodfelter KH, Fu B, Han B, Ho YC, Kley N, Liang X, Liederer BM, Lin J, Mukadam S, et al. Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties. Bioorganic & Medicinal Chemistry Letters. 23: 3531-8. PMID 23668988 DOI: 10.1016/J.Bmcl.2013.04.040  1
2013 Poulin P, Hop CE, Salphati L, Liederer BM. Correlation of tissue-plasma partition coefficients between normal tissues and subcutaneous xenografts of human tumor cell lines in mouse as a prediction tool of drug penetration in tumors. Journal of Pharmaceutical Sciences. 102: 1355-69. PMID 23334959 DOI: 10.1002/Jps.23452  1
2013 Lin J, Sampath D, Nannini MA, Lee BB, Degtyarev M, Oeh J, Savage H, Guan Z, Hong R, Kassees R, Lee LB, Risom T, Gross S, Liederer BM, Koeppen H, et al. Targeting activated Akt with GDC-0068, a novel selective Akt inhibitor that is efficacious in multiple tumor models. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 1760-72. PMID 23287563 DOI: 10.1158/1078-0432.Ccr-12-3072  1
2013 Ding X, Ghobarah H, Zhang X, Jaochico A, Liu X, Deshmukh G, Liederer BM, Hop CE, Dean B. High-throughput liquid chromatography/mass spectrometry method for the quantitation of small molecules using accurate mass technologies in supporting discovery drug screening. Rapid Communications in Mass Spectrometry : Rcm. 27: 401-8. PMID 23280971 DOI: 10.1002/Rcm.6461  1
2013 Liederer BM, Berezhkovskiy LM, Ubhayakar SS, Deng Y. An alternative approach for quantitative bioanalysis using diluted blood to profile oral exposure of small molecule anticancer drugs in mice. Journal of Pharmaceutical Sciences. 102: 750-60. PMID 23225118 DOI: 10.1002/Jps.23395  1
2013 Diaz D, Ford KA, Hartley DP, Harstad EB, Cain GR, Achilles-Poon K, Nguyen T, Peng J, Zheng Z, Merchant M, Sutherlin DP, Gaudino JJ, Kaus R, Lewin-Koh SC, Choo EF, ... Liederer BM, et al. Pharmacokinetic drivers of toxicity for basic molecules: strategy to lower pKa results in decreased tissue exposure and toxicity for a small molecule Met inhibitor. Toxicology and Applied Pharmacology. 266: 86-94. PMID 23142475 DOI: 10.1016/J.Taap.2012.10.026  1
2012 Blake JF, Xu R, Bencsik JR, Xiao D, Kallan NC, Schlachter S, Mitchell IS, Spencer KL, Banka AL, Wallace EM, Gloor SL, Martinson M, Woessner RD, Vigers GP, Brandhuber BJ, ... ... Liederer BM, et al. Discovery and preclinical pharmacology of a selective ATP-competitive Akt inhibitor (GDC-0068) for the treatment of human tumors. Journal of Medicinal Chemistry. 55: 8110-27. PMID 22934575 DOI: 10.1021/Jm301024W  1
2012 Liu X, Ding X, Deshmukh G, Liederer BM, Hop CE. Use of the cassette-dosing approach to assess brain penetration in drug discovery. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 963-9. PMID 22328585 DOI: 10.1124/Dmd.111.044420  1
2012 Liederer BM, Liu X, Berezhkovskiy LM, Cain G, Ding X, Gaudino J, Kaus R, Plise EG, Sutherlin DP, Harstad EB. Preclinical stereoselective disposition and toxicokinetics of two novel MET inhibitors. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 42: 456-65. PMID 22122353 DOI: 10.3109/00498254.2011.632697  1
2011 Liang X, Ubhayakar S, Liederer BM, Dean B, Ran-Ran Qin A, Shahidi-Latham S, Deng Y. Evaluation of homogenization techniques for the preparation of mouse tissue samples to support drug discovery. Bioanalysis. 3: 1923-33. PMID 21899502 DOI: 10.4155/Bio.11.181  1
2011 Liederer BM, Berezhkovskiy LM, Dean BJ, Dinkel V, Peng J, Merchant M, Plise EG, Wong H, Liu X. Preclinical absorption, distribution, metabolism, excretion, and pharmacokinetic-pharmacodynamic modelling of N-(4-(3-((3S,4R)-1-ethyl-3-fluoropiperidine-4-ylamino)-1H-pyrazolo[3,4-b]pyridin-4-yloxy)-3-fluorophenyl)-2-(4-fluorophenyl)-3-oxo-2,3-dihydropyridazine-4-carboxamide, a novel MET kinase inhibitor. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 41: 327-39. PMID 21182395 DOI: 10.3109/00498254.2010.542500  1
2006 Liederer BM, Borchardt RT. Enzymes involved in the bioconversion of ester-based prodrugs. Journal of Pharmaceutical Sciences. 95: 1177-95. PMID 16639719 DOI: 10.1002/Jps.20542  1
2006 Liederer BM, Fuchs T, Vander Velde D, Siahaan TJ, Borchardt RT. Effects of amino acid chirality and the chemical linker on the cell permeation characteristics of cyclic prodrugs of opioid peptides. Journal of Medicinal Chemistry. 49: 1261-70. PMID 16480263 DOI: 10.1021/Jm050277F  1
2005 Liederer BM, Phan KT, Ouyang H, Borchardt RT. Significant differences in the disposition of cyclic prodrugs of opioid peptides in rats and guinea pigs following IV administration. Journal of Pharmaceutical Sciences. 94: 2676-87. PMID 16258984 DOI: 10.1002/Jps.20476  1
2005 Liederer BM, Borchardt RT. Stability of oxymethyl-modified coumarinic acid cyclic prodrugs of diastereomeric opioid peptides in biological media from various animal species including human. Journal of Pharmaceutical Sciences. 94: 2198-206. PMID 16136552 DOI: 10.1002/Jps.20452  1
2002 Proniuk S, Liederer BM, Blanchard J. Preformulation study of epigallocatechin gallate, a promising antioxidant for topical skin cancer prevention. Journal of Pharmaceutical Sciences. 91: 111-6. PMID 11782902 DOI: 10.1002/Jps.10009  1
2002 Proniuk S, Liederer BM, Dixon SE, Rein JA, Kallen MA, Blanchard J. Topical formulation studies with DEET (N,N-diethyl-3-methylbenzamide) and cyclodextrins. Journal of Pharmaceutical Sciences. 91: 101-10. PMID 11782901 DOI: 10.1002/Jps.1172  1
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