Roberto Tinoco, Ph.D. - Publications

Affiliations: 
2010 Biology University of California, San Diego, La Jolla, CA 
Area:
Virology Biology, Microbiology Biology

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Neubert EN, DeRogatis JM, Lewis SA, Viramontes KM, Ortega P, Henriquez ML, Buisson R, Messaoudi I, Tinoco R. HMGB2 regulates the differentiation and stemness of exhausted CD8 T cells during chronic viral infection and cancer. Nature Communications. 14: 5631. PMID 37704621 DOI: 10.1038/s41467-023-41352-0  0.585
2023 Hope JL, Otero DC, Bae EA, Stairiker CJ, Palete AB, Faso HA, Lin M, Henriquez ML, Roy S, Seo H, Lei X, Wang ES, Chow S, Tinoco R, Daniels GA, et al. PSGL-1 attenuates early TCR signaling to suppress CD8 T cell progenitor differentiation and elicit terminal CD8 T cell exhaustion. Cell Reports. 42: 112436. PMID 37115668 DOI: 10.1016/j.celrep.2023.112436  0.773
2023 DeRogatis JM, Neubert EN, Viramontes KM, Henriquez ML, Nicholas DA, Tinoco R. Cell-Intrinsic CD38 Expression Sustains Exhausted CD8 T Cells by Regulating Their Survival and Metabolism during Chronic Viral Infection. Journal of Virology. e0022523. PMID 37039663 DOI: 10.1128/jvi.00225-23  0.504
2022 Viramontes KM, Neubert EN, DeRogatis JM, Tinoco R. PD-1 Immune Checkpoint Blockade and PSGL-1 Inhibition Synergize to Reinvigorate Exhausted T Cells. Frontiers in Immunology. 13: 869768. PMID 35774790 DOI: 10.3389/fimmu.2022.869768  0.618
2022 DeRogatis JM, Viramontes KM, Neubert EN, Henriquez ML, Guerrero-Juarez CF, Tinoco R. Targeting the PSGL-1 Immune Checkpoint Promotes Immunity to PD-1 Resistant Melanoma. Cancer Immunology Research. PMID 35303066 DOI: 10.1158/2326-6066.CIR-21-0690  0.406
2021 Tinoco R, Neubert EN, Stairiker CJ, Henriquez ML, Bradley LM. PSGL-1 Is a T Cell Intrinsic Inhibitor That Regulates Effector and Memory Differentiation and Responses During Viral Infection. Frontiers in Immunology. 12: 677824. PMID 34326837 DOI: 10.3389/fimmu.2021.677824  0.729
2021 DeRogatis JM, Viramontes KM, Neubert EN, Tinoco R. PSGL-1 Immune Checkpoint Inhibition for CD4 T Cell Cancer Immunotherapy. Frontiers in Immunology. 12: 636238. PMID 33708224 DOI: 10.3389/fimmu.2021.636238  0.589
2020 Li Y, Elmén L, Segota I, Xian Y, Tinoco R, Feng Y, Fujita Y, Segura Muñoz RR, Schmaltz R, Bradley LM, Ramer-Tait A, Zarecki R, Long T, Peterson SN, Ronai ZA. Prebiotic-Induced Anti-tumor Immunity Attenuates Tumor Growth. Cell Reports. 30: 1753-1766.e6. PMID 32049008 DOI: 10.1016/J.Celrep.2020.01.035  0.584
2020 Scortegagna M, Hockemeyer K, Dolgalev I, Poźniak J, Rambow F, Li Y, Feng Y, Tinoco R, Otero DC, Zhang T, Brown K, Bosenberg M, Bradley LM, Marine JC, Aifantis I, et al. Siah2 control of T-regulatory cells limits anti-tumor immunity. Nature Communications. 11: 99. PMID 31911617 DOI: 10.1038/S41467-019-13826-7  0.674
2019 Li Y, Tinoco R, Elmén L, Segota I, Xian Y, Fujita Y, Sahu A, Zarecki R, Marie K, Feng Y, Khateb A, Frederick DT, Ashkenazi SK, Kim H, Perez EG, et al. Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5 mice. Nature Communications. 10: 1492. PMID 30940817 DOI: 10.1038/S41467-019-09525-Y  0.734
2018 Fujita Y, Khateb A, Li Y, Tinoco R, Zhang T, Bar-Yoseph H, Tam MA, Chowers Y, Sabo E, Gerassy-Vainberg S, Starosvetsky E, James B, Brown K, Shen-Orr SS, Bradley LM, et al. Regulation of S100A8 Stability by RNF5 in Intestinal Epithelial Cells Determines Intestinal Inflammation and Severity of Colitis. Cell Reports. 24: 3296-3311.e6. PMID 30232010 DOI: 10.1016/j.celrep.2018.08.057  0.599
2018 Borlido J, Sakuma S, Raices M, Carrette F, Tinoco R, Bradley LM, D'Angelo MA. Nuclear pore complex-mediated modulation of TCR signaling is required for naïve CD4 T cell homeostasis. Nature Immunology. PMID 29736031 DOI: 10.1038/S41590-018-0103-5  0.796
2018 Tinoco R, Carrette F, Henriquez ML, Fujita Y, Bradley LM. Fucosyltransferase Induction during Influenza Virus Infection Is Required for the Generation of Functional Memory CD4T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 29491007 DOI: 10.4049/Jimmunol.1701251  0.763
2017 Tinoco R, Bradley LM. Targeting the PSGL-1 pathway for immune modulation. Immunotherapy. 9: 785-788. PMID 28877633 DOI: 10.2217/Imt-2017-0078  0.595
2017 Tinoco R, Otero DC, Takahashi AA, Bradley LM. PSGL-1: A New Player in the Immune Checkpoint Landscape. Trends in Immunology. PMID 28262471 DOI: 10.1016/J.It.2017.02.002  0.751
2016 Tinoco R, Carrette F, Barraza ML, Otero DC, Magaña J, Bosenberg MW, Swain SL, Bradley LM. PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion. Immunity. 44: 1470. PMID 27332735 DOI: 10.1016/J.Immuni.2016.05.011  0.781
2016 Tinoco R, Carrette F, Barraza ML, Otero DC, Magaña J, Bosenberg MW, Swain SL, Bradley LM. PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion. Immunity. 44: 1190-203. PMID 27192578 DOI: 10.1016/J.Immuni.2016.04.015  0.8
2012 Baaten BJ, Tinoco R, Chen AT, Bradley LM. Regulation of Antigen-Experienced T Cells: Lessons from the Quintessential Memory Marker CD44. Frontiers in Immunology. 3: 23. PMID 22566907 DOI: 10.3389/Fimmu.2012.00023  0.795
2009 Tinoco R, Alcalde V, Yang Y, Sauer K, Zuniga EI. Cell-intrinsic transforming growth factor-beta signaling mediates virus-specific CD8+ T cell deletion and viral persistence in vivo. Immunity. 31: 145-57. PMID 19604493 DOI: 10.1016/J.Immuni.2009.06.015  0.742
2009 Kerdiles YM, Beisner DR, Tinoco R, Dejean AS, Castrillon DH, DePinho RA, Hedrick SM. Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor. Nature Immunology. 10: 176-84. PMID 19136962 DOI: 10.1038/Ni.1689  0.511
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