Jacob A. Galan, Ph.D. - Related publications

Affiliations: 
2010 Biochemistry Purdue University, West Lafayette, IN, United States 
Area:
Biochemistry, Analytical Chemistry
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Kim PR, Zhang S, Rahmat MB, Koh CG. Partners in crime: POPX2 phosphatase and its interacting proteins in cancer. Cell Death & Disease. 11: 840. PMID 33037179 DOI: 10.1038/s41419-020-03061-0   
2020 Ma H, Liu S, Liu Y, Zhu J, Han XX, Ozaki Y, Zhao B. In-situ fingerprinting phosphorylated proteins via surface-enhanced Raman spectroscopy: Single-site discrimination of Tau biomarkers in Alzheimer's disease. Biosensors & Bioelectronics. 171: 112748. PMID 33113381 DOI: 10.1016/j.bios.2020.112748   
2020 Zhang JF, Liu B, Hong I, Mo A, Roth RH, Tenner B, Lin W, Zhang JZ, Molina RS, Drobizhev M, Hughes TE, Tian L, Huganir RL, Mehta S, Zhang J. An ultrasensitive biosensor for high-resolution kinase activity imaging in awake mice. Nature Chemical Biology. PMID 32989297 DOI: 10.1038/s41589-020-00660-y   
2020 Fang CY, Lai TC, Hsiao M, Chang YC. The Diverse Roles of TAO Kinases in Health and Diseases. International Journal of Molecular Sciences. 21. PMID 33050415 DOI: 10.3390/ijms21207463   
2020 Qiao G, Bi K, Liu J, Cao S, Liu M, Pešić M, Lin X. Protein kinases as targets for developing anticancer agents from marine organisms. Biochimica Et Biophysica Acta. General Subjects. 129759. PMID 33038451 DOI: 10.1016/j.bbagen.2020.129759   
2020 Tran T, Mitra J, Ha T, Kavran JM. Increasing kinase domain proximity promotes MST2 autophosphorylation during Hippo signaling. The Journal of Biological Chemistry. PMID 32994222 DOI: 10.1074/jbc.RA120.015723   
2020 Jena S, Damayanti NP, Tan J, Pratt ED, Irudayaraj JMK, Parker LL. Multiplexable fluorescence lifetime imaging (FLIM) probes for Abl and Src-family kinases. Chemical Communications (Cambridge, England). PMID 33035286 DOI: 10.1039/d0cc05030j   
2020 Martinez R, Huang W, Samadani R, Mackowiak B, Centola G, Chen L, Conlon IL, Hom K, Kane MA, Fletcher S, Shapiro P. Mechanistic analysis of an ERK2-interacting compound that inhibits mutant-BRAF expressing melanoma cells by inducing oxidative stress. The Journal of Pharmacology and Experimental Therapeutics. PMID 33109619 DOI: 10.1124/jpet.120.000266   
2020 Agarwal S, Rath PP, Anand G, Gourinath S. Uncovering the Cyclic AMP Signaling Pathway of the Protozoan Parasite and Understanding Its Role in Phagocytosis. Frontiers in Cellular and Infection Microbiology. 10: 566726. PMID 33102254 DOI: 10.3389/fcimb.2020.566726   
2020 Felgueiras J, Jerónimo C, Fardilha M. Protein phosphatase 1 in tumorigenesis: is it worth a closer look? Biochimica Et Biophysica Acta. Reviews On Cancer. 1874: 188433. PMID 32956763 DOI: 10.1016/j.bbcan.2020.188433   
2020 Chen CW, Huang LY, Liao CF, Chang KP, Chu YW. GasPhos: Protein Phosphorylation Site Prediction Using a New Feature Selection Approach with a GA-Aided Ant Colony System. International Journal of Molecular Sciences. 21. PMID 33114312 DOI: 10.3390/ijms21217891   
2020 Rashid MM, Shatabda S, Hasan MM, Kurata H. Recent Development of Machine Learning Methods in Microbial Phosphorylation Sites. Current Genomics. 21: 194-203. PMID 33071613 DOI: 10.2174/1389202921666200427210833   
2020 Song P, Song B, Liu J, Wang X, Nan X, Wang J. Blockage of PAK1 alleviates the proliferation and invasion of NSCLC cells via inhibiting ERK and AKT signaling activity. Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. PMID 32974862 DOI: 10.1007/s12094-020-02486-5   
2020 Asih PR, Prikas E, Stefanoska K, Tan ARP, Ahel HI, Ittner A. Functions of p38 MAP Kinases in the Central Nervous System. Frontiers in Molecular Neuroscience. 13: 570586. PMID 33013322 DOI: 10.3389/fnmol.2020.570586   
2020 Xu W, Wang Y. Post-translational Modifications of Serine/Threonine and Histidine Kinases and Their Roles in Signal Transductions in Synechocystis Sp. PCC 6803. Applied Biochemistry and Biotechnology. PMID 33159456 DOI: 10.1007/s12010-020-03435-2   
2020 Tian Y, Zhao L. Metformin induces apoptosis of melanoma B16 cells via PI3K/Akt/mTOR signaling pathways. Journal of B.U.On. : Official Journal of the Balkan Union of Oncology. 25: 2066-2070. PMID 33099954   
2020 Stein V, Blank-Landeshammer B, Müntjes K, Märker R, Teichert I, Feldbrügge M, Sickmann A, Kück U. The STRIPAK signaling complex regulates dephosphorylation of GUL1, an RNA-binding protein that shuttles on endosomes. Plos Genetics. 16: e1008819. PMID 32997654 DOI: 10.1371/journal.pgen.1008819   
2020 Liang Y, Zhang T, Ren L, Jing S, Li Z, Zuo P, Li T, Wang Y, Zhang J, Wei Z. Cucurbitacin IIb induces apoptosis and cell cycle arrest through regulating EGFR/MAPK pathway. Environmental Toxicology and Pharmacology. 103542. PMID 33161110 DOI: 10.1016/j.etap.2020.103542   
2020 Liu R, Chen Y, Liu G, Li C, Song Y, Cao Z, Li W, Hu J, Lu C, Liu Y. PI3K/AKT pathway as a key link modulates the multidrug resistance of cancers. Cell Death & Disease. 11: 797. PMID 32973135 DOI: 10.1038/s41419-020-02998-6   
2020 Huang J, Feng W, Li S, Tang H, Qin S, Li W, Gong Y, Fang Y, Liu Y, Wang S, Guo Y, Xu Z, Shen Q. Berberine Exerts Anti-cancer Activity by Modulating Adenosine Monophosphate-Activated Protein Kinase (AMPK) and the Phosphatidylinositol 3-Kinase/Protein Kinase B (PI3K/AKT) Signaling Pathways. Current Pharmaceutical Design. PMID 32988344 DOI: 10.2174/1381612826666200928155728   
2020 Song J, Bai J, Wang S, Liu L, Zhao Z. [Effects of Quercetin on Autophagy and Phosphatidylinositol 3-kinase/Protein Kinase B/Mammalian Target of Rapamycin Signaling Pathway in Human Prostate Cancer PC-3 Cells]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae. 42: 578-584. PMID 33131510 DOI: 10.3881/j.issn.1000-503X.12361   
2020 Yun MW, Kim K, Park JY, Chung KY. Conformational Dynamics Analysis of MEK1 Using Hydrogen/Deuterium Exchange Mass Spectrometry. Protein and Peptide Letters. PMID 33143608 DOI: 10.2174/0929866527666201103152534   
2020 Cho JH, Kim K, Kim SA, Park S, Park BO, Kim JH, Kim SY, Kwon MJ, Han MH, Lee SB, Park BC, Park SG, Kim JH, Kim S. Deubiquitinase OTUD5 is a positive regulator of mTORC1 and mTORC2 signaling pathways. Cell Death and Differentiation. PMID 33110214 DOI: 10.1038/s41418-020-00649-z   
2020 Dai C, Shen L, Jin W, Lv B, Liu P, Wang X, Yin Y, Fu Y, Liang L, Ma Z, Zhang X, Wang Y, Xu D, Chen Z. Physapubescin B enhances the sensitivity of gastric cancer cells to trametinib by inhibiting the STAT3 signaling pathway. Toxicology and Applied Pharmacology. 115273. PMID 33035574 DOI: 10.1016/j.taap.2020.115273   
2020 Kumar S, Singh SK, Rana B, Rana A. The regulatory function of mixed lineage kinase 3 in tumor and host immunity. Pharmacology & Therapeutics. 107704. PMID 33045253 DOI: 10.1016/j.pharmthera.2020.107704   
2020 Takeuchi T, Lin YT, Fekaris N, Umen JG, Sears BB, Benning C. Modulation of CHT7 complexes during light/dark- and nitrogen-mediated life-cycle transitions of Chlamydomonas. Plant Physiology. PMID 33004613 DOI: 10.1104/pp.20.00864   
2020 Amraei R, Alwani T, Ho RX, Aryan Z, Wang S, Rahimi N. Cell adhesion molecule IGPR-1 activates AMPK connecting cell adhesion to autophagy. The Journal of Biological Chemistry. PMID 32978258 DOI: 10.1074/jbc.RA120.014790   
2020 Bogdanow B, Schmidt M, Weisbach H, Gruska I, Vetter B, Imami K, Ostermann E, Brune W, Selbach M, Hagemeier C, Wiebusch L. Cross-regulation of viral kinases with cyclin A secures shutoff of host DNA synthesis. Nature Communications. 11: 4845. PMID 32973148 DOI: 10.1038/s41467-020-18542-1   
2020 Tiwari A, Iida M, Kosnopfel C, Abbariki M, Menegakis A, Fehrenbacher B, Maier J, Schaller M, Brucker SY, Wheeler DL, Harari PM, Rothbauer U, Schittek B, Zips D, Toulany M. Blocking Y-Box Binding Protein-1 through Simultaneous Targeting of PI3K and MAPK in Triple Negative Breast Cancers. Cancers. 12. PMID 33003386 DOI: 10.3390/cancers12102795   
2020 Tiwari A, Iida M, Kosnopfel C, Abbariki M, Menegakis A, Fehrenbacher B, Maier J, Schaller M, Brucker SY, Wheeler DL, Harari PM, Rothbauer U, Schittek B, Zips D, Toulany M. Blocking Y-Box Binding Protein-1 through Simultaneous Targeting of PI3K and MAPK in Triple Negative Breast Cancers. Cancers. 12. PMID 33003386 DOI: 10.3390/cancers12102795   
2020 Li Y, Shi J, Yang J, Ge S, Zhang J, Jia R, Fan X. Uveal melanoma: progress in molecular biology and therapeutics. Therapeutic Advances in Medical Oncology. 12: 1758835920965852. PMID 33149769 DOI: 10.1177/1758835920965852   
2020 Ertosun MG, DİlmaÇ S, Hapİl FZ, TanriÖver G, KÖksoy S, ÖzeŞ ON. Regulation of E2F1 activity via PKA-mediated phosphorylations. Turkish Journal of Biology = Turk Biyoloji Dergisi. 44: 215-229. PMID 33110360 DOI: 10.3906/biy-2003-9   
2020 Makino T, Mizawa M, Yoshihisa Y, Yamamoto S, Tabuchi Y, Miyai M, Hibino T, Sasahara M, Shimizu T. Trichohyalin-like 1 protein plays a crucial role in proliferation and anti-apoptosis of normal human keratinocytes and squamous cell carcinoma cells. Cell Death Discovery. 6: 109. PMID 33133644 DOI: 10.1038/s41420-020-00344-5   
2020 Alme EB, Toczyski DP. Redundant targeting of Isr1 by two CDKs in mitotic cells. Current Genetics. PMID 33063175 DOI: 10.1007/s00294-020-01110-x   
2020 Roberto J, Sykes CE, Vacratsis PO. Characterization of Phosphopeptide Positional Isomers on the Transcriptional Co-activator TAZ. Biochemistry. PMID 33086783 DOI: 10.1021/acs.biochem.0c00521   
2020 Jeong H, Park S, Kim SY, Cho SH, Jeong MS, Kim SR, Seo JB, Kim SH, Kim KN. 1-Cinnamoyltrichilinin from Causes Apoptosis through the p38 MAPK Pathway in HL-60 Human Leukemia Cells. International Journal of Molecular Sciences. 21. PMID 33053881 DOI: 10.3390/ijms21207506   
2020 Zheng S, Tao W. Targeting Cullin-RING E3 Ligases for Radiosensitization: From NEDDylation Inhibition to PROTACs. Frontiers in Oncology. 10: 1517. PMID 32983997 DOI: 10.3389/fonc.2020.01517   
2020 Buckles TC, Ohashi Y, Tremel S, McLaughlin SH, Pardon E, Steyaert J, Gordon M, Williams RL, Falke JJ. Regulation of a Class III PI3K Lipid Kinase (VPS34 Complex II) by the Small G Protein Rab5A: Single Molecule Analysis Reveals a Dual Regulatory Mechanism. Biophysical Journal. PMID 33137306 DOI: 10.1016/j.bpj.2020.10.028   
2020 Soamalala J, Diot S, Pellerano M, Blanquart C, Galibert M, Jullian M, Puget K, Morris MC. Fluorescent peptide biosensor for probing CDK6 activity in lung cancer cell extracts. Chembiochem : a European Journal of Chemical Biology. PMID 33112024 DOI: 10.1002/cbic.202000677   
2020 Rajagopalan K, Dworkin J. Escherichia coli YegI is a novel Ser/Thr kinase lacking conserved motifs that localizes to the inner membrane. Febs Letters. PMID 32888201 DOI: 10.1002/1873-3468.13920   
2020 Tetenborg S, Wang HY, Nemitz L, Depping A, Espejo AB, Aseervatham J, Bedford MT, Janssen-Bienhold U, O'Brien J, Dedek K. Phosphorylation of Connexin36 near the C-terminus switches binding affinities for PDZ-domain and 14-3-3 proteins in vitro. Scientific Reports. 10: 18378. PMID 33110101 DOI: 10.1038/s41598-020-75375-0   
2020 Sharifinejad N, Azizi G, Behniafard N, Zaki-Dizaji M, Jamee M, Yazdani R, Abolhassani H, Aghamohammadi A. Protein Kinase C-Delta Defect in Autoimmune Lymphoproliferative Syndrome-Like Disease: First Case from the National Iranian Registry and Review of the Literature. Immunological Investigations. 1-12. PMID 33047643 DOI: 10.1080/08820139.2020.1829638   
2020 Gopallawa I, Lee RJ. Targeting the phosphoinositide-3-kinase/protein kinase B pathway in airway innate immunity. World Journal of Biological Chemistry. 11: 30-51. PMID 33024516 DOI: 10.4331/wjbc.v11.i2.30   
2020 Ye X, Vogt MS, van der Does C, Bildl W, Schulte U, Essen LO, Albers SV. The Phosphatase PP2A Interacts With ArnA and ArnB to Regulate the Oligomeric State and the Stability of the ArnA/B Complex. Frontiers in Microbiology. 11: 1849. PMID 32973695 DOI: 10.3389/fmicb.2020.01849   
2020 Elzwawi A, Grafton G, Barnes NM, Mehellou Y. SPAK and OSR1 kinases bind and phosphorylate the β-Adrenergic receptor. Biochemical and Biophysical Research Communications. 532: 88-93. PMID 32828531 DOI: 10.1016/j.bbrc.2020.07.143   
2020 Kim MJ, Kang YJ, Sung B, Jang JY, Ahn YR, Oh HJ, Choi H, Choi I, Im E, Moon HR, Chung HY, Kim ND. Novel SIRT Inhibitor, MHY2256, Induces Cell Cycle Arrest, Apoptosis, and Autophagic Cell Death in HCT116 Human Colorectal Cancer Cells. Biomolecules & Therapeutics. PMID 33073770 DOI: 10.4062/biomolther.2020.153   
2020 Waschbüsch D, Khan AR. Phosphorylation of Rab GTPases in the regulation of membrane trafficking. Traffic (Copenhagen, Denmark). PMID 32969543 DOI: 10.1111/tra.12765   
2020 Lu X, Cui S, Zhang Y, Xu S, Ju X, Niu Q. [Regulatory role of Ca MK-Ⅱ and PP2A on hyperphosphorylated tau induced by Al Cl_3 in SH-SY5Y cells]. Wei Sheng Yan Jiu = Journal of Hygiene Research. 49: 534-539. PMID 32928344 DOI: 10.19813/j.cnki.weishengyanjiu.2020.04.002   
2020 Abdel Aziz MH, Fan Y, Liu L, Moasser M, Fu H, Jura N, Arkin MR. Expression and Purification of Active Human Kinases Using Pichia pastoris as A General-Purpose Host. Protein Expression and Purification. 105780. PMID 33115654 DOI: 10.1016/j.pep.2020.105780   
2020 Iannuzzi CA, Indovina P, Forte IM, Di Somma S, Malfitano AM, Bruno M, Portella G, Pentimalli F, Giordano A. Pharmacological Inhibition of WEE1 Potentiates the Antitumoral Effect of the Oncolytic Virus in Malignant Mesothelioma Cell Lines. International Journal of Molecular Sciences. 21. PMID 33020398 DOI: 10.3390/ijms21197333