Year |
Citation |
Score |
2018 |
Lee S, Cheung-See-Kit M, Williams TA, Yamout N, Zufferey R. The glycosomal alkyl-dihydroxyacetonephosphate synthase TbADS is essential for the synthesis of ether glycerophospholipids in procyclic trypanosomes. Experimental Parasitology. PMID 29355496 DOI: 10.1016/J.Exppara.2018.01.014 |
0.592 |
|
2017 |
Biagiotti M, Dominguez S, Yamout N, Zufferey R. Lipidomics and anti-trypanosomatid chemotherapy. Clinical and Translational Medicine. 6: 27. PMID 28766182 DOI: 10.1186/S40169-017-0160-7 |
0.406 |
|
2017 |
Zufferey R, Pirani K, Cheung-See-Kit M, Lee S, Williams TA, Chen DG, Hossain MF. The Trypanosoma brucei dihydroxyacetonephosphate acyltransferase TbDAT is dispensable for normal growth but important for synthesis of ether glycerophospholipids. Plos One. 12: e0181432. PMID 28715456 DOI: 10.1371/Journal.Pone.0181432 |
0.571 |
|
2016 |
Patel N, Pirani KA, Zhu T, Cheung-See-Kit M, Lee S, Chen DG, Zufferey R. The Glycerol-3-Phosphate Acyltransferase TbGAT Is Dispensable for Viability and the Synthesis of Glycerolipids in Trypanosoma brucei. The Journal of Eukaryotic Microbiology. PMID 26909872 DOI: 10.1111/Jeu.12309 |
0.683 |
|
2016 |
Zufferey R. In Vitro Assay to Measure Phosphatidylethanolamine Methyltransferase Activity. Journal of Visualized Experiments : Jove. PMID 26780155 DOI: 10.3791/53302 |
0.457 |
|
2014 |
Bibis SS, Dahlstrom K, Zhu T, Zufferey R. Characterization of Leishmania major phosphatidylethanolamine methyltransferases LmjPEM1 and LmjPEM2 and their inhibition by choline analogs. Molecular and Biochemical Parasitology. 196: 90-9. PMID 25176160 DOI: 10.1016/J.Molbiopara.2014.08.005 |
0.511 |
|
2012 |
Zufferey R, Bibis SS, Zhu T, Dhalladoo S. Characterization of a compensatory mutant of Leishmania major that lacks ether lipids but exhibits normal growth, and G418 and hygromycin resistance. Experimental Parasitology. 130: 200-4. PMID 22306069 DOI: 10.1016/J.Exppara.2012.01.008 |
0.508 |
|
2011 |
Al-Ani GK, Patel N, Pirani KA, Zhu T, Dhalladoo S, Zufferey R. The N-terminal domain and glycosomal localization of Leishmania initial acyltransferase LmDAT are important for lipophosphoglycan synthesis. Plos One. 6: e27802. PMID 22114698 DOI: 10.1371/Journal.Pone.0027802 |
0.677 |
|
2009 |
Zufferey R, Al-Ani GK, Dunlap K. Leishmania dihydroxyacetonephosphate acyltransferase LmDAT is important for ether lipid biosynthesis but not for the integrity of detergent resistant membranes. Molecular and Biochemical Parasitology. 168: 177-85. PMID 19720088 DOI: 10.1016/J.Molbiopara.2009.08.006 |
0.592 |
|
2006 |
Zufferey R, Ben Mamoun C. Leishmania major expresses a single dihydroxyacetone phosphate acyltransferase localized in the glycosome, important for rapid growth and survival at high cell density and essential for virulence. The Journal of Biological Chemistry. 281: 7952-9. PMID 16423830 DOI: 10.1074/Jbc.M512911200 |
0.48 |
|
2005 |
Zufferey R, Mamoun CB. The initial step of glycerolipid metabolism in Leishmania major promastigotes involves a single glycerol-3-phosphate acyltransferase enzyme important for the synthesis of triacylglycerol but not essential for virulence. Molecular Microbiology. 56: 800-10. PMID 15819633 DOI: 10.1111/J.1365-2958.2005.04579.X |
0.521 |
|
2004 |
Roggero R, Zufferey R, Minca M, Richier E, Calas M, Vial H, Ben Mamoun C. Unraveling the mode of action of the antimalarial choline analog G25 in Plasmodium falciparum and Saccharomyces cerevisiae. Antimicrobial Agents and Chemotherapy. 48: 2816-24. PMID 15273086 DOI: 10.1128/Aac.48.8.2816-2824.2004 |
0.394 |
|
2004 |
Santiago TC, Zufferey R, Mehra RS, Coleman RA, Mamoun CB. The Plasmodium falciparum PfGatp is an endoplasmic reticulum membrane protein important for the initial step of malarial glycerolipid synthesis. The Journal of Biological Chemistry. 279: 9222-32. PMID 14668349 DOI: 10.1074/Jbc.M310502200 |
0.422 |
|
2003 |
Zufferey R, Allen S, Barron T, Sullivan DR, Denny PW, Almeida IC, Smith DF, Turco SJ, Ferguson MA, Beverley SM. Ether phospholipids and glycosylinositolphospholipids are not required for amastigote virulence or for inhibition of macrophage activation by Leishmania major. The Journal of Biological Chemistry. 278: 44708-18. PMID 12944391 DOI: 10.1074/Jbc.M308063200 |
0.482 |
|
2002 |
Zufferey R, Mamoun CB. Choline transport in Leishmania major promastigotes and its inhibition by choline and phosphocholine analogs. Molecular and Biochemical Parasitology. 125: 127-34. PMID 12467980 DOI: 10.1016/S0166-6851(02)00220-7 |
0.328 |
|
1998 |
Zufferey R, Arslan E, Thöny-Meyer L, Hennecke H. How replacements of the 12 conserved histidines of subunit I affect assembly, cofactor binding, and enzymatic activity of the Bradyrhizobium japonicum cbb3-type oxidase Journal of Biological Chemistry. 273: 6452-6459. PMID 9497378 DOI: 10.1074/Jbc.273.11.6452 |
0.321 |
|
1997 |
Reiss G, Te Heesen S, Gilmore R, Zufferey R, Aebi M. A specific screen for oligosaccharyltransferase mutations identifies the 9 kDa OST5 protein required for optimal activity in vivo and in vitro Embo Journal. 16: 1164-1172. PMID 9135133 DOI: 10.1093/Emboj/16.6.1164 |
0.391 |
|
1996 |
Preisig O, Zufferey R, Hennecke H. The Bradyrhizobium japonicum fixGHIS genes are required for the formation of the high-affinity cbb3-type cytochrome oxidase Archives of Microbiology. 165: 297-305. PMID 8661920 DOI: 10.1007/S002030050330 |
0.335 |
|
1996 |
Preisig O, Zufferey R, Thöny-Meyer L, Appleby CA, Hennecke H. A high-affinity cbb3-type cytochrome oxidase terminates the symbiosis-specific respiratory chain of Bradyrhizobium japonicum Journal of Bacteriology. 178: 1532-1538. PMID 8626278 DOI: 10.1128/Jb.178.6.1532-1538.1996 |
0.3 |
|
1996 |
Zufferey R, Preisig O, Hennecke H, Thöny-Meyer L. Assembly and function of the cytochrome cbb3 oxidase subunits in Bradyrhizobium japonicum Journal of Biological Chemistry. 271: 9114-9119. PMID 8621562 DOI: 10.1074/Jbc.271.15.9114 |
0.364 |
|
1995 |
Zufferey R, Knauer R, Burda P, Stagljar I, Te Heesen S, Lehle L, Aebi M. STT3, a highly conserved protein required for yeast oligosaccharyl transferase activity in vivo Embo Journal. 14: 4949-4960. PMID 7588624 |
0.413 |
|
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