Joseph Loscalzo - Publications

Affiliations: 
Boston University, Boston, MA, United States 
Area:
Molecular Biology, Biochemistry

318 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Cheng F, Lu W, Liu C, Fang J, Hou Y, Handy DE, Wang R, Zhao Y, Yang Y, Huang J, Hill DE, Vidal M, Eng C, Loscalzo J. A genome-wide positioning systems network algorithm for in silico drug repurposing. Nature Communications. 10: 3476. PMID 31375661 DOI: 10.1038/s41467-019-10744-6  0.32
2018 Cheng F, Desai RJ, Handy DE, Wang R, Schneeweiss S, Barabási AL, Loscalzo J. Network-based approach to prediction and population-based validation of in silico drug repurposing. Nature Communications. 9: 2691. PMID 30002366 DOI: 10.1038/s41467-018-05116-5  0.32
2017 Zarrabi AJ, Kao D, Nguyen DT, Loscalzo J, Handy DE. Hypoxia-induced suppression of c-Myc by HIF-2α in human pulmonary endothelial cells attenuates TFAM expression. Cellular Signalling. PMID 28709643 DOI: 10.1016/j.cellsig.2017.07.008  0.32
2017 Xiao W, Wang RS, Handy DE, Loscalzo J. NAD(H) and NADP(H) Redox Couples and Cellular Energy Metabolism. Antioxidants & Redox Signaling. PMID 28648096 DOI: 10.1089/ars.2017.7216  0.32
2016 Handy DE, Loscalzo J. Responses to Reductive Stress in the Cardiovascular System. Free Radical Biology & Medicine. PMID 27940350 DOI: 10.1016/j.freeradbiomed.2016.12.006  0.32
2016 Mirzakhani H, Litonjua AA, McElrath TF, O'Connor G, Lee-Parritz A, Iverson R, Macones G, Strunk RC, Bacharier LB, Zeiger R, Hollis BW, Handy DE, Sharma A, Laranjo N, Carey V, ... ... Loscalzo J, et al. Early pregnancy vitamin D status and risk of preeclampsia. The Journal of Clinical Investigation. PMID 27841759 DOI: 10.1172/JCI89031  0.32
2016 Gladyshev VN, Arnér ES, Berry MJ, Brigelius-Flohé R, Bruford EA, Burk RF, Carlson BA, Castellano S, Chavatte L, Conrad M, Copeland PR, Diamond AM, Driscoll DM, Ferreiro A, Flohé L, ... ... Loscalzo J, et al. Selenoprotein Gene Nomenclature. The Journal of Biological Chemistry. PMID 27645994 DOI: 10.1074/jbc.M116.756155  0.32
2016 Zang T, Pottenplackel LP, Handy DE, Loscalzo J, Dai S, Deth RC, Zhou ZS, Ma J. Comparison of Protein N-Homocysteinylation in Rat Plasma under Elevated Homocysteine Using a Specific Chemical Labeling Method. Molecules (Basel, Switzerland). 21. PMID 27617989 DOI: 10.3390/molecules21091195  0.32
2016 Loscalzo J. Adaptions to Hypoxia and Redox Stress: Essential Concepts Confounded by Misleading Terminology. Circulation Research. 119: 511-3. PMID 27492841 DOI: 10.1161/CIRCRESAHA.116.309394  0.44
2016 Loscalzo J. Looking Back, Looking Forward: Reflections on Tenure as Editor of Circulation. Circulation. 133: 2599-600. PMID 27324353 DOI: 10.1161/CIRCULATIONAHA.116.023452  0.44
2016 Loscalzo J. The Future of Medical Journal Publishing: The Journal Editor's Perspective: Looking Back, Looking Forward. Circulation. 133: 1621-4. PMID 27142606 DOI: 10.1161/CIRCULATIONAHA.116.022519  0.44
2016 Wang RS, Loscalzo J. Illuminating drug action by network integration of disease genes: a case study of myocardial infarction. Molecular Biosystems. PMID 27004607 DOI: 10.1039/c6mb00052e  0.44
2016 Garmaroudi FS, Handy DE, Liu YY, Loscalzo J. Systems Pharmacology and Rational Polypharmacy: Nitric Oxide-Cyclic GMP Signaling Pathway as an Illustrative Example and Derivation of the General Case. Plos Computational Biology. 12: e1004822. PMID 26985825 DOI: 10.1371/journal.pcbi.1004822  0.32
2016 Mogabgab ON, Osman NY, Wei K, Batal I, Loscalzo J. CLINICAL PROBLEM-SOLVING. A Complementary Affair. The New England Journal of Medicine. 374: 74-81. PMID 26735996 DOI: 10.1056/NEJMcps1404086  0.44
2015 Barroso M, Kao D, Blom HJ, Tavares de Almeida I, Castro R, Loscalzo J, Handy DE. S-adenosylhomocysteine induces inflammation through NFkB: A possible role for EZH2 in endothelial cell activation. Biochimica Et Biophysica Acta. 1862: 82-92. PMID 26506125 DOI: 10.1016/j.bbadis.2015.10.019  0.32
2015 Geller BJ, Stone RM, Merola JF, Levy BD, Loscalzo J. A Man with Fever, Cough, and Rash. The New England Journal of Medicine. 373: 74-80. PMID 26132944 DOI: 10.1056/NEJMcps1404270  0.44
2015 Hall KT, Loscalzo J, Kaptchuk TJ. Genetics and the placebo effect: the placebome. Trends in Molecular Medicine. 21: 285-94. PMID 25883069 DOI: 10.1016/j.molmed.2015.02.009  0.44
2015 Fox CS, Hall JL, Arnett DK, Ashley EA, Delles C, Engler MB, Freeman MW, Johnson JA, Lanfear DE, Liggett SB, Lusis AJ, Loscalzo J, MacRae CA, Musunuru K, Newby LK, et al. Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association. Circulation. 131: 1715-36. PMID 25882488 DOI: 10.1161/CIR.0000000000000211  0.44
2015 Fox CS, Bonaca MA, Ryan JJ, Massaro JM, Barry K, Loscalzo J. Response to letters regarding article, "A randomized trial of social media from Circulation". Circulation. 131: e396. PMID 25825407 DOI: 10.1161/CIRCULATIONAHA.115.016083  0.44
2015 Joseph J, Loscalzo J. Nutri(meta)genetics and cardiovascular disease: novel concepts in the interaction of diet and genomic variation. Current Atherosclerosis Reports. 17: 505. PMID 25782777 DOI: 10.1007/s11883-015-0505-x  0.44
2015 Schaefer L, Paik JM, Rennke H, Levy BD, Loscalzo J. Clinical problem solving: Itching for a diagnosis. The New England Journal of Medicine. 372: 964-8. PMID 25738673 DOI: 10.1056/NEJMcps1409348  0.44
2015 Menche J, Sharma A, Kitsak M, Ghiassian SD, Vidal M, Loscalzo J, Barabási AL. Disease networks. Uncovering disease-disease relationships through the incomplete interactome. Science (New York, N.Y.). 347: 1257601. PMID 25700523 DOI: 10.1126/science.1257601  0.44
2015 Bader AR, Li T, Wang W, Kohane DS, Loscalzo J, Zhang YY. Preparation and characterization of SDF-1α-chitosan-dextran sulfate nanoparticles. Journal of Visualized Experiments : Jove. 52323. PMID 25650558 DOI: 10.3791/52323  0.44
2015 Loscalzo J. Maintenance of certification: Good intentions gone awry. Trends in Cardiovascular Medicine. 25: 312-4. PMID 25618320 DOI: 10.1016/j.tcm.2014.12.011  0.44
2015 Benjamin I, Brown N, Burke G, Correa A, Houser SR, Jones DW, Loscalzo J, Vasan RS, Whitman GR. American Heart Association Cardiovascular Genome-Phenome Study: foundational basis and program. Circulation. 131: 100-12. PMID 25411155 DOI: 10.1161/CIRCULATIONAHA.114.014190  0.44
2014 Tang SS, Guillermier C, Wang M, Poczatek JC, Suzuki N, Loscalzo J, Lechene C. Quantitative imaging of selenoprotein with multi-isotope imaging mass spectrometry (MIMS). Surface and Interface Analysis : Sia. 46: 154-157. PMID 26379338 DOI: 10.1002/sia.5625  0.44
2014 Price C, Ashbaugh C, Miller AL, Loscalzo J. Clinical problem-solving. A chilly fever. The New England Journal of Medicine. 371: 1833-7. PMID 25372092 DOI: 10.1056/NEJMcps1313772  0.44
2014 Bui AH, O'Gara PT, Economy KE, Miller AL, Loscalzo J. Clinical problem-solving. A tight predicament. The New England Journal of Medicine. 371: 953-9. PMID 25184868 DOI: 10.1056/NEJMcps1304030  0.44
2014 Hall KT, Nelson CP, Davis RB, Buring JE, Kirsch I, Mittleman MA, Loscalzo J, Samani NJ, Ridker PM, Kaptchuk TJ, Chasman DI. Polymorphisms in catechol-O-methyltransferase modify treatment effects of aspirin on risk of cardiovascular disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 2160-7. PMID 25035343 DOI: 10.1161/ATVBAHA.114.303845  0.44
2014 Loscalzo J, Handy DE. Epigenetic modifications: basic mechanisms and role in cardiovascular disease (2013 Grover Conference series). Pulmonary Circulation. 4: 169-74. PMID 25006435 DOI: 10.1086/675979  0.32
2014 Maron BA, Oldham WM, Chan SY, Vargas SO, Arons E, Zhang YY, Loscalzo J, Leopold JA. Upregulation of steroidogenic acute regulatory protein by hypoxia stimulates aldosterone synthesis in pulmonary artery endothelial cells to promote pulmonary vascular fibrosis. Circulation. 130: 168-79. PMID 25001622 DOI: 10.1161/CIRCULATIONAHA.113.007690  0.44
2014 Loscalzo J. Keshan disease, selenium deficiency, and the selenoproteome. The New England Journal of Medicine. 370: 1756-60. PMID 24785212 DOI: 10.1056/NEJMcibr1402199  0.44
2014 Gibson CJ, Britton KA, Miller AL, Loscalzo J. Clinical problem-solving. Out of the blue. The New England Journal of Medicine. 370: 1742-8. PMID 24785210 DOI: 10.1056/NEJMcps1213589  0.44
2014 Baffy G, Loscalzo J. Complexity and network dynamics in physiological adaptation: an integrated view. Physiology & Behavior. 131: 49-56. PMID 24751342 DOI: 10.1016/j.physbeh.2014.04.018  0.44
2014 Barroso M, Florindo C, Kalwa H, Silva Z, Turanov AA, Carlson BA, de Almeida IT, Blom HJ, Gladyshev VN, Hatfield DL, Michel T, Castro R, Loscalzo J, Handy DE. Inhibition of cellular methyltransferases promotes endothelial cell activation by suppressing glutathione peroxidase 1 protein expression. The Journal of Biological Chemistry. 289: 15350-62. PMID 24719327 DOI: 10.1074/jbc.M114.549782  0.44
2014 Loscalzo J. A celebration of failure. Circulation. 129: 953-5. PMID 24589694 DOI: 10.1161/CIRCULATIONAHA.114.009220  0.44
2014 Goodman R, Dellaripa PF, Miller AL, Loscalzo J. Clinical problem-solving. An unusual case of abdominal pain. The New England Journal of Medicine. 370: 70-5. PMID 24382068 DOI: 10.1056/NEJMcps1215559  0.44
2014 Cottrill KA, Chan SY, Loscalzo J. Hypoxamirs and mitochondrial metabolism. Antioxidants & Redox Signaling. 21: 1189-201. PMID 24111795 DOI: 10.1089/ars.2013.5641  0.44
2013 Handy DE, Loscalzo J, Leopold JA. Systems analysis of oxidant stress in the vasculature. Iubmb Life. 65: 911-20. PMID 24265198 DOI: 10.1002/iub.1221  0.32
2013 Liao JM, Stewart GC, Padera RF, Miller AL, Loscalzo J. Clinical problem-solving. A curious case of chest pain. The New England Journal of Medicine. 369: 1844-50. PMID 24195552 DOI: 10.1056/NEJMcps1301819  0.44
2013 Maron BA, Loscalzo J. Pulmonary hypertension: pathophysiology and signaling pathways. Handbook of Experimental Pharmacology. 218: 31-58. PMID 24092335 DOI: 10.1007/978-3-642-38664-0_2  0.44
2013 Yin T, Bader AR, Hou TK, Maron BA, Kao DD, Qian R, Kohane DS, Handy DE, Loscalzo J, Zhang YY. SDF-1α in glycan nanoparticles exhibits full activity and reduces pulmonary hypertension in rats. Biomacromolecules. 14: 4009-20. PMID 24059347 DOI: 10.1021/bm401122q  0.44
2013 Fox MC, Lakdawala N, Miller AL, Loscalzo J. Clinical problem-solving. A patient with syncope. The New England Journal of Medicine. 369: 966-72. PMID 24004124 DOI: 10.1056/NEJMcps1300093  0.44
2013 Loscalzo J. The identification of nitric oxide as endothelium-derived relaxing factor. Circulation Research. 113: 100-3. PMID 23833290 DOI: 10.1161/CIRCRESAHA.113.301577  0.44
2013 Kao DD, Oldebeken SR, Rai A, Lubos E, Leopold JA, Loscalzo J, Handy DE. Tumor necrosis factor-α-mediated suppression of dual-specificity phosphatase 4: Crosstalk between NFκB and MAPK regulates endothelial cell survival Molecular and Cellular Biochemistry. 382: 153-162. PMID 23812841 DOI: 10.1007/s11010-013-1730-7  0.44
2013 Maron BA, Waxman AB, Opotowsky AR, Gillies H, Blair C, Aghamohammadzadeh R, Loscalzo J, Leopold JA. Effectiveness of spironolactone plus ambrisentan for treatment of pulmonary arterial hypertension (from the [ARIES] study 1 and 2 trials). The American Journal of Cardiology. 112: 720-5. PMID 23751938 DOI: 10.1016/j.amjcard.2013.04.051  0.44
2013 Scully EP, Klompas M, Morgan EA, Miller AL, Loscalzo J. Clinical problem-solving. Waiting for the other foot to drop. The New England Journal of Medicine. 368: 2220-5. PMID 23738548 DOI: 10.1056/NEJMcps1210603  0.44
2013 Fox CS, Loscalzo J. Editor's note. Circulation. 127: 1353. PMID 23662311 DOI: 10.1161/01.CIR.0000155446.20314.7D  0.44
2013 Loscalzo J. Gut microbiota, the genome, and diet in atherogenesis. The New England Journal of Medicine. 368: 1647-9. PMID 23614591 DOI: 10.1056/NEJMe1302154  0.44
2013 Loscalzo J. Ever at the mercy of well-intentioned regulations: their adverse consequences and unproven benefits. Circulation. 127: 1169-72. PMID 23509030 DOI: 10.1161/CIRCULATIONAHA.113.002075  0.44
2013 Loscalzo J. Venous thrombosis in the nephrotic syndrome. The New England Journal of Medicine. 368: 956-8. PMID 23465106 DOI: 10.1056/NEJMcibr1209459  0.44
2013 Loscalzo J. From clinical observation to mechanism--Heyde's syndrome. The New England Journal of Medicine. 368: 579-80. PMID 23388020 DOI: 10.1056/NEJMc1215053  0.44
2013 Silverman EK, Loscalzo J. Developing new drug treatments in the era of network medicine Clinical Pharmacology and Therapeutics. 93: 26-28. PMID 23212105 DOI: 10.1038/clpt.2012.207  0.44
2013 Maron BA, Tang SS, Loscalzo J. S-nitrosothiols and the S-nitrosoproteome of the cardiovascular system. Antioxidants & Redox Signaling. 18: 270-87. PMID 22770551 DOI: 10.1089/ars.2012.4744  0.44
2012 Balderman JA, Lee HY, Mahoney CE, Handy DE, White K, Annis S, Lebeche D, Hajjar RJ, Loscalzo J, Leopold JA. Bone morphogenetic protein-2 decreases microRNA-30b and microRNA-30c to promote vascular smooth muscle cell calcification. Journal of the American Heart Association. 1: e003905. PMID 23316327 DOI: 10.1161/JAHA.112.003905  0.32
2012 Zhang Z, Yang Z, Zhu B, Hu J, Liew CW, Zhang Y, Leopold JA, Handy DE, Loscalzo J, Stanton RC. Increasing glucose 6-phosphate dehydrogenase activity restores redox balance in vascular endothelial cells exposed to high glucose. Plos One. 7: e49128. PMID 23185302 DOI: 10.1371/journal.pone.0049128  0.32
2012 Loscalzo J. From clinical observation to mechanism--Heyde's syndrome. The New England Journal of Medicine. 367: 1954-6. PMID 23150964 DOI: 10.1056/NEJMcibr1205363  0.44
2012 Metes-Kosik N, Luptak I, Dibello PM, Handy DE, Tang SS, Zhi H, Qin F, Jacobsen DW, Loscalzo J, Joseph J. Both selenium deficiency and modest selenium supplementation lead to myocardial fibrosis in mice via effects on redox-methylation balance. Molecular Nutrition & Food Research. 56: 1812-24. PMID 23097236 DOI: 10.1002/mnfr.201200386  0.44
2012 Kajstura J, Rota M, Cappetta D, Ogórek B, Arranto C, Bai Y, Ferreira-Martins J, Signore S, Sanada F, Matsuda A, Kostyla J, Caballero MV, Fiorini C, D'Alessandro DA, Michler RE, ... ... Loscalzo J, et al. Cardiomyogenesis in the aging and failing human heart. Circulation. 126: 1869-81. PMID 22955965 DOI: 10.1161/CIRCULATIONAHA.112.118380  0.44
2012 Silverman EK, Loscalzo J. Network medicine approaches to the genetics of complex diseases. Discovery Medicine. 14: 143-52. PMID 22935211  0.44
2012 Rhee DK, Clark RP, Blair RJ, Katz JT, Loscalzo J. Clinical problem-solving. Breathtaking journey. The New England Journal of Medicine. 367: 452-7. PMID 22853017 DOI: 10.1056/NEJMcps1103955  0.44
2012 Kajstura J, Bai Y, Cappetta D, Kim J, Arranto C, Sanada F, D'Amario D, Matsuda A, Bardelli S, Ferreira-Martins J, Hosoda T, Leri A, Rota M, Loscalzo J, Anversa P. Tracking chromatid segregation to identify human cardiac stem cells that regenerate extensively the infarcted myocardium. Circulation Research. 111: 894-906. PMID 22851539 DOI: 10.1161/CIRCRESAHA.112.273649  0.44
2012 Chan SY, Loscalzo J. The emerging paradigm of network medicine in the study of human disease. Circulation Research. 111: 359-74. PMID 22821909 DOI: 10.1161/CIRCRESAHA.111.258541  0.44
2012 Maron BA, Zhang YY, White K, Chan SY, Handy DE, Mahoney CE, Loscalzo J, Leopold JA. Aldosterone inactivates the endothelin-B receptor via a cysteinyl thiol redox switch to decrease pulmonary endothelial nitric oxide levels and modulate pulmonary arterial hypertension. Circulation. 126: 963-74. PMID 22787113 DOI: 10.1161/CIRCULATIONAHA.112.094722  0.32
2012 Merola JF, Ghoroghchian PP, Samuels MA, Levy BD, Loscalzo J. Clinical problem-solving. At a loss. The New England Journal of Medicine. 367: 67-72. PMID 22762321 DOI: 10.1056/NEJMcps1111668  0.44
2012 Ueland PM, Loscalzo J. Homocysteine and cardiovascular risk: the perils of reductionism in a complex system. Clinical Chemistry. 58: 1623-5. PMID 22623744 DOI: 10.1373/clinchem.2012.187286  0.44
2012 Solomon DA, Fanta CH, Levy BD, Loscalzo J. Clinical problem-solving. Whistling in the dark. The New England Journal of Medicine. 366: 1725-30. PMID 22551132 DOI: 10.1056/NEJMcps1106363  0.44
2012 Loscalzo J. Irreproducible experimental results: causes, (mis)interpretations, and consequences. Circulation. 125: 1211-4. PMID 22412087 DOI: 10.1161/CIRCULATIONAHA.112.098244  0.44
2012 Rinne ML, McGinnis SM, Samuels MA, Katz JT, Loscalzo J. Clinical problem-solving. A startling decline. The New England Journal of Medicine. 366: 836-42. PMID 22375976 DOI: 10.1056/NEJMcps1104209  0.44
2012 Parikh VN, Jin RC, Rabello S, Gulbahce N, White K, Hale A, Cottrill KA, Shaik RS, Waxman AB, Zhang YY, Maron BA, Hartner JC, Fujiwara Y, Orkin SH, Haley KJ, ... ... Loscalzo J, et al. MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: results of a network bioinformatics approach. Circulation. 125: 1520-32. PMID 22371328 DOI: 10.1161/CIRCULATIONAHA.111.060269  0.44
2012 Loscalzo J. Personalized cardiovascular medicine and drug development: time for a new paradigm. Circulation. 125: 638-45. PMID 22294708 DOI: 10.1161/CIRCULATIONAHA.111.089243  0.44
2012 Wang X, Cui L, Joseph J, Jiang B, Pimental D, Handy DE, Liao R, Loscalzo J. Homocysteine induces cardiomyocyte dysfunction and apoptosis through p38 MAPK-mediated increase in oxidant stress. Journal of Molecular and Cellular Cardiology. 52: 753-60. PMID 22227328 DOI: 10.1016/j.yjmcc.2011.12.009  0.32
2012 Gavin MC, Morse D, Partridge AH, Levy BD, Loscalzo J. Clinical problem-solving. Breathless. The New England Journal of Medicine. 366: 75-81. PMID 22216845 DOI: 10.1056/NEJMcps1011918  0.44
2012 Handy DE, Loscalzo J. Redox regulation of mitochondrial function Antioxidants and Redox Signaling. 16: 1323-1367. PMID 22146081 DOI: 10.1089/ars.2011.4123  0.44
2012 Malinouski M, Kehr S, Finney L, Vogt S, Carlson BA, Seravalli J, Jin R, Handy DE, Park TJ, Loscalzo J, Hatfield DL, Gladyshev VN. High-resolution imaging of selenium in kidneys: a localized selenium pool associated with glutathione peroxidase 3. Antioxidants & Redox Signaling. 16: 185-92. PMID 21854231 DOI: 10.1089/ars.2011.3997  0.44
2011 Loscalzo J, Barabasi AL. Systems biology and the future of medicine. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 3: 619-27. PMID 21928407 DOI: 10.1002/wsbm.144  0.44
2011 Liberman M, Johnson RC, Handy DE, Loscalzo J, Leopold JA. Bone morphogenetic protein-2 activates NADPH oxidase to increase endoplasmic reticulum stress and human coronary artery smooth muscle cell calcification. Biochemical and Biophysical Research Communications. 413: 436-41. PMID 21907184 DOI: 10.1016/j.bbrc.2011.08.114  0.32
2011 Horwitz RI, Kassirer JP, Holmboe ES, Humphrey HJ, Verghese A, Croft C, Kwok M, Loscalzo J. Internal medicine residency redesign: Proposal of the internal medicine working group American Journal of Medicine. 124: 806-812. PMID 21854887 DOI: 10.1016/j.amjmed.2011.03.007  0.44
2011 Lubos E, Kelly NJ, Oldebeken SR, Leopold JA, Zhang YY, Loscalzo J, Handy DE. Glutathione peroxidase-1 deficiency augments proinflammatory cytokine-induced redox signaling and human endothelial cell activation Journal of Biological Chemistry. 286: 35407-35417. PMID 21852236 DOI: 10.1074/jbc.M110.205708  0.44
2011 Loscalzo J. Lipid metabolism by gut microbes and atherosclerosis Circulation Research. 109: 127-129. PMID 21737814 DOI: 10.1161/RES.0b013e3182290620  0.44
2011 Zhang J, Handy DE, Wang Y, Bouchard G, Selhub J, Loscalzo J, Carey MC. Hyperhomocysteinemia from trimethylation of hepatic phosphatidylethanolamine during cholesterol cholelithogenesis in inbred mice. Hepatology (Baltimore, Md.). 54: 697-706. PMID 21567442 DOI: 10.1002/hep.24428  0.44
2011 Kajstura J, Rota M, Hall SR, Hosoda T, D'Amario D, Sanada F, Zheng H, Ogórek B, Rondon-Clavo C, Ferreira-Martins J, Matsuda A, Arranto C, Goichberg P, Giordano G, Haley KJ, ... ... Loscalzo J, et al. Evidence for human lung stem cells. The New England Journal of Medicine. 364: 1795-806. PMID 21561345 DOI: 10.1056/NEJMoa1101324  0.44
2011 Loscalzo J. Systems biology and personalized medicine: A network approach to human disease Proceedings of the American Thoracic Society. 8: 196-198. PMID 21543801 DOI: 10.1513/pats.201006-041MS  0.44
2011 Jin RC, Mahoney CE, Coleman Anderson L, Ottaviano F, Croce K, Leopold JA, Zhang YY, Tang SS, Handy DE, Loscalzo J. Glutathione peroxidase-3 deficiency promotes platelet-dependent thrombosis in vivo. Circulation. 123: 1963-73. PMID 21518981 DOI: 10.1161/CIRCULATIONAHA.110.000034  0.44
2011 Loscalzo J. Can scientific quality be quantified? Circulation. 123: 947-950. PMID 21382902 DOI: 10.1161/CIRCULATIONAHA.111.020529  0.44
2011 Vaidya A, Kaiser UB, Levy BD, Loscalzo J. Clinical problem-solving. Lying low. The New England Journal of Medicine. 364: 871-5. PMID 21366479 DOI: 10.1056/NEJMcps0903869  0.44
2011 Fisher M, Loscalzo J. The perils of combination antithrombotic therapy and potential resolutions. Stroke; a Journal of Cerebral Circulation. 42: 278-81. PMID 21263146 DOI: 10.1161/STROKEAHA.110.609404  0.44
2011 Fisher M, Loscalzo J. The perils of combination antithrombotic therapy and potential resolutions. Circulation. 123: 232-5. PMID 21263004 DOI: 10.1161/CIR.0b013e31820841ce  0.44
2011 Labunskyy VM, Lee BC, Handy DE, Loscalzo J, Hatfield DL, Gladyshev VN. Both maximal expression of selenoproteins and selenoprotein deficiency can promote development of type 2 diabetes-like phenotype in mice. Antioxidants & Redox Signaling. 14: 2327-36. PMID 21194350 DOI: 10.1089/ars.2010.3526  0.44
2011 Barabási AL, Gulbahce N, Loscalzo J. Network medicine: a network-based approach to human disease. Nature Reviews. Genetics. 12: 56-68. PMID 21164525 DOI: 10.1038/nrg2918  0.44
2011 Lee AI, Koo S, Vaidya A, Katz JT, Loscalzo J. A bird's-eye view of fever New England Journal of Medicine. 365: 1727-1732. DOI: 10.1056/NEJMcps1012518  0.44
2011 Arnett DK, Loscalzo J. Inaccurate information in capitol health call article Jama - Journal of the American Medical Association. 305: 256-257.  0.44
2010 Loscalzo J. The cellular response to hypoxia: Tuning the system with microRNAs Journal of Clinical Investigation. 120: 3815-3817. PMID 20972325 DOI: 10.1172/JCI45105  0.44
2010 Erzurum S, Rounds SI, Stevens T, Aldred M, Aliotta J, Archer SL, Asosingh K, Balaban R, Bauer N, Bhattacharya J, Bogaard H, Choudhary G, Dorn GW, Dweik R, Fagan K, ... ... Loscalzo J, et al. Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report. American Journal of Respiratory and Critical Care Medicine. 182: 1554-62. PMID 20833821 DOI: 10.1164/rccm.201006-0869WS  0.44
2010 Levison JH, Barbieri RL, Katz JT, Loscalzo J. Hard to conceive New England Journal of Medicine. 363: 965-970. PMID 20818907 DOI: 10.1056/NEJMcps0810360  0.44
2010 Liu AY, Lowe RC, Levy BD, Katz JT, Loscalzo J. A rash hypothesis New England Journal of Medicine. 363: 72-78. PMID 20592300 DOI: 10.1056/NEJMcps0708369  0.44
2010 Lauten EH, VerBerkmoes J, Choi J, Jin R, Edwards DA, Loscalzo J, Zhang YY. Nanoglycan complex formulation extends VEGF retention time in the lung. Biomacromolecules. 11: 1863-72. PMID 20575564 DOI: 10.1021/bm100384z  0.44
2010 Zeller T, Wild P, Szymczak S, Rotival M, Schillert A, Castagne R, Maouche S, Germain M, Lackner K, Rossmann H, Eleftheriadis M, Sinning CR, Schnabel RB, Lubos E, Mennerich D, ... ... Loscalzo J, et al. Genetics and beyond--the transcriptome of human monocytes and disease susceptibility. Plos One. 5: e10693. PMID 20502693 DOI: 10.1371/journal.pone.0010693  0.44
2010 McMahon G, Katz JT, Thorndike ME, Levy BD, Loscalzo J. Evaluation of a redesign initiative in an internal-medicine residency New England Journal of Medicine. 362: 1304-1311. PMID 20375407 DOI: 10.1056/NEJMsa0908136  0.44
2010 Chan SY, Loscalzo J. MicroRNA-210: A unique and pleiotropic hypoxamir Cell Cycle. 9: 1072-1083. PMID 20237418  0.44
2010 Lubos E, Mahoney CE, Leopold JA, Zhang YY, Loscalzo J, Handy DE. Glutathione peroxidase-1 modulates lipopolysaccharide-induced adhesion molecule expression in endothelial cells by altering CD14 expression. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2525-32. PMID 20219985 DOI: 10.1096/fj.09-147421  0.32
2010 Chamarthi B, Morris CA, Kaiser UB, Katz JT, Loscalzo J. Clinical problem-solving. Stalking the diagnosis. The New England Journal of Medicine. 362: 834-9. PMID 20200388 DOI: 10.1056/NEJMcps0806157  0.44
2010 Johnson JA, Everett BM, Katz JT, Loscalzo J. Painful purple toes New England Journal of Medicine. 362: 67-73. PMID 20054049 DOI: 10.1056/NEJMcps0807291  0.44
2010 Zhang Z, Liew CW, Handy DE, Zhang Y, Leopold JA, Hu J, Guo L, Kulkarni RN, Loscalzo J, Stanton RC. High glucose inhibits glucose-6-phosphate dehydrogenase, leading to increased oxidative stress and beta-cell apoptosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 1497-505. PMID 20032314 DOI: 10.1096/fj.09-136572  0.32
2010 Lubos E, Sinning CR, Schnabel RB, Wild PS, Zeller T, Rupprecht HJ, Bickel C, Lackner KJ, Peetz D, Loscalzo J, Münzel T, Blankenberg S. Serum selenium and prognosis in cardiovascular disease: results from the AtheroGene study. Atherosclerosis. 209: 271-7. PMID 19836749 DOI: 10.1016/j.atherosclerosis.2009.09.008  0.44
2010 Xu Y, Zhang Z, Hu J, Stillman IE, Leopold JA, Handy DE, Loscalzo J, Stanton RC. Glucose-6-phosphate dehydrogenase-deficient mice have increased renal oxidative stress and increased albuminuria. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 609-16. PMID 19805580 DOI: 10.1096/fj.09-135731  0.32
2010 Loscalzo J. Antioxidant enzyme deficiencies and vascular disease Expert Review of Endocrinology and Metabolism. 5: 15-18. DOI: 10.1586/eem.09.41  0.44
2010 Kwong RY, Loscalzo J. Diagnostic and therapeutic cardiovascular procedures Circulation. 122: 1897. DOI: 10.1161/CIRCULATIONAHA.110.990408  0.44
2010 Beckman JA, Loscalzo J. Circulation cardiovascular case series Circulation. 122: 1661. DOI: 10.1161/CIRCULATIONAHA.110.989160  0.44
2010 Britton KA, Stevenson WG, Levy BD, Katz JT, Loscalzo J. The beat goes on New England Journal of Medicine. 362: 1721-1726+1662. DOI: 10.1056/NEJMcps0801473  0.44
2009 Cuker A, Connors JM, Katz JT, Levy BD, Loscalzo J. A bloody mystery New England Journal of Medicine. 361: 1887-1894+1826. PMID 19890132 DOI: 10.1056/NEJMcps066546  0.44
2009 Loscalzo J. Homocysteine-mediated thrombosis and angiostasis in vascular pathobiology Journal of Clinical Investigation. 119: 3203-3205. PMID 19841539 DOI: 10.1172/JCI40924  0.44
2009 Lim CC, Bryan NS, Jain M, Garcia-Saura MF, Fernandez BO, Sawyer DB, Handy DE, Loscalzo J, Feelisch M, Liao R. Glutathione peroxidase deficiency exacerbates ischemia-reperfusion injury in male but not female myocardium: insights into antioxidant compensatory mechanisms. American Journal of Physiology. Heart and Circulatory Physiology. 297: H2144-53. PMID 19801492 DOI: 10.1152/ajpheart.00673.2009  0.44
2009 Leopold JA, Loscalzo J. Oxidative risk for atherothrombotic cardiovascular disease Free Radical Biology and Medicine. 47: 1673-1706. PMID 19751821 DOI: 10.1016/j.freeradbiomed.2009.09.009  0.44
2009 Bitton A, Yialamas M, Levy BD, Katz JT, Loscalzo J. Clinical problem-solving. A fragile balance. The New England Journal of Medicine. 361: 74-9. PMID 19571286 DOI: 10.1056/NEJMcps0806370  0.44
2009 Loscalzo J. Pilot trials in clinical research: Of what value are they? Circulation. 119: 1694-1696. PMID 19349331 DOI: 10.1161/CIRCULATIONAHA.109.861625  0.44
2009 Ottaviano FG, Tang SS, Handy DE, Loscalzo J. Regulation of the extracellular antioxidant selenoprotein plasma glutathione peroxidase (GPx-3) in mammalian cells. Molecular and Cellular Biochemistry. 327: 111-26. PMID 19219623 DOI: 10.1007/s11010-009-0049-x  0.44
2009 Maron BA, Zhang YY, Handy DE, Beuve A, Tang SS, Loscalzo J, Leopold JA. Aldosterone increases oxidant stress to impair guanylyl cyclase activity by cysteinyl thiol oxidation in vascular smooth muscle cells. The Journal of Biological Chemistry. 284: 7665-72. PMID 19141618 DOI: 10.1074/jbc.M809460200  0.44
2009 Malhotra A, Loscalzo J. Sleep and Cardiovascular Disease: An Overview Progress in Cardiovascular Diseases. 51: 279-284. PMID 19110129 DOI: 10.1016/j.pcad.2008.10.004  0.44
2009 Goldhaber SZ, Loscalzo J. Circulation: Editor's note Circulation. 120: 1168. DOI: 10.1161/CIRCULATIONAHA.109.899757  0.44
2009 Loscalzo J. Circulation: Editor's note Circulation. 119: 5. DOI: 10.1161/CIRCULATIONAHA.108.833699  0.44
2009 Wolpin BM, Weller PF, Katz JT, Levy BD, Loscalzo J. The writing on the wall New England Journal of Medicine. 361: 1387-1392. DOI: 10.1056/NEJMcps0707685  0.44
2009 Leopold JA, Loscalzo J. The biology of vascular nitric oxide Disorders of Hemoglobin: Genetics, Pathophysiology, and Clinical Management, Second Edition. 185-200. DOI: 10.1017/CBO9780511596582.015  0.44
2008 Loscalzo J. Paraoxonase and coronary heart disease risk: language misleads, linkage misinforms, function clarifies Circulation. Cardiovascular Genetics. 1: 79-80. PMID 20031548  0.44
2008 Ector H, Lancellotti P, Roberts WC, Wenger NK, Moss AJ, Smith ER, Borer JS, Eagle KA, Freedman J, Krum H, Lang C, Remme WJ, Piper HM, White CJ, Loscalzo J, et al. A statement on ethics from the HEART Group. Jacc. Cardiovascular Imaging. 1: 410-2. PMID 19356460 DOI: 10.1016/j.jcmg.2008.02.001  0.44
2008 Loscalzo J. Membrane Redox State and Apoptosis: Death by Peroxide Cell Metabolism. 8: 182-183. PMID 18762018 DOI: 10.1016/j.cmet.2008.08.004  0.44
2008 Sung AD, Cheng S, Moslehi J, Scully EP, Prior JM, Loscalzo J. Hepatocellular carcinoma with intracavitary cardiac involvement: a case report and review of the literature. The American Journal of Cardiology. 102: 643-5. PMID 18721529 DOI: 10.1016/j.amjcard.2008.04.042  0.44
2008 Blicharz TM, Rissin DM, Bowden M, Hayman RB, DiCesare C, Bhatia JS, Grand-Pierre N, Siqueira WL, Helmerhorst EJ, Loscalzo J, Oppenheim FG, Walt DR. Use of colorimetric test strips for monitoring the effect of hemodialysis on salivary nitrite and uric acid in patients with end-stage renal disease: a proof of principle. Clinical Chemistry. 54: 1473-80. PMID 18676588 DOI: 10.1373/clinchem.2008.105320  0.44
2008 Loscalzo J, Tomaselli GF, Vaughan DE, Walsh RA. Task force 7: training in cardiovascular research. Journal of the American College of Cardiology. 51: 380-3. PMID 18206756 DOI: 10.1016/j.jacc.2007.11.015  0.44
2008 Ottaviano FG, Handy DE, Loscalzo J. Redox regulation in the extracellular environment. Circulation Journal : Official Journal of the Japanese Circulation Society. 72: 1-16. PMID 18159092 DOI: JST.JSTAGE/circj/72.1  0.44
2008 Voetsch B, Jin RC, Bierl C, Deus-Silva L, Camargo EC, Annichino-Bizacchi JM, Handy DE, Loscalzo J. Role of promoter polymorphisms in the plasma glutathione peroxidase (GPx-3) gene as a risk factor for cerebral venous thrombosis. Stroke; a Journal of Cerebral Circulation. 39: 303-7. PMID 18096833 DOI: 10.1161/STROKEAHA.107.490094  0.32
2008 Chan SY, Loscalzo J. Pathogenic mechanisms of pulmonary arterial hypertension Journal of Molecular and Cellular Cardiology. 44: 14-30. PMID 17950310 DOI: 10.1016/j.yjmcc.2007.09.006  0.44
2008 Loscalzo J. A bold, new initiative for circulation: A family of subspecialty journals Circulation. 117: 4-5. DOI: 10.1161/CIRCULATIONAHA.107.755710  0.44
2007 Maron BA, Loscalzo J. Should hyperhomocysteinemia be treated in patients with atherosclerotic disease? Current Atherosclerosis Reports. 9: 375-383. PMID 18001620 DOI: 10.1007/s11883-007-0048-x  0.44
2007 Loscalzo J. Association studies in an era of too much information: Clinical analysis of new biomarker and genetic data Circulation. 116: 1866-1870. PMID 17965399 DOI: 10.1161/CIRCULATIONAHA.107.741611  0.44
2007 Letts G, Loscalzo J. Frontiers in nephrology: Targeting inflammation using novel nitric oxide donors Journal of the American Society of Nephrology. 18: 2863-2869. PMID 17942956 DOI: 10.1681/ASN.2007030321  0.44
2007 Rajasekaran NS, Connell P, Christians ES, Yan LJ, Taylor RP, Orosz A, Zhang XQ, Stevenson TJ, Peshock RM, Leopold JA, Barry WH, Loscalzo J, Odelberg SJ, Benjamin IJ. Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice. Cell. 130: 427-39. PMID 17693254 DOI: 10.1016/j.cell.2007.06.044  0.44
2007 Loscalzo J. Entrepreneurship in the medical academy: Possibilities and challenges in commercialization of research discoveries Circulation. 115: 1504-1507. PMID 17389277 DOI: 10.1161/CIRCULATIONAHA.107.694869  0.44
2007 Leopold JA, Dam A, Maron BA, Scribner AW, Liao R, Handy DE, Stanton RC, Pitt B, Loscalzo J. Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity. Nature Medicine. 13: 189-97. PMID 17273168 DOI: 10.1038/nm1545  0.32
2007 Voetsch B, Jin RC, Bierl C, Benke KS, Kenet G, Simioni P, Ottaviano F, Damasceno BP, Annichino-Bizacchi JM, Handy DE, Loscalzo J. Promoter polymorphisms in the plasma glutathione peroxidase (GPx-3) gene: a novel risk factor for arterial ischemic stroke among young adults and children. Stroke; a Journal of Cerebral Circulation. 38: 41-9. PMID 17122425 DOI: 10.1161/01.STR.0000252027.53766.2b  0.44
2007 Voetsch B, Loscalzo J. Response to letter by Grond-Ginsbach et al [2] Stroke. 38. DOI: 10.1161/STROKEAHA.106.480079  0.44
2007 Raiesdana A, Loscalzo J. Vessel wall-derived substances affecting platelets Platelets in Hematologic and Cardiovascular Disorders: a Clinical Handbook. 92-105. DOI: 10.1017/CBO9780511545276.008  0.44
2007 Yang Y, Loscalzo J. S-nitrosated proteins: Formation, metabolism, and function Radicals For Life: the Various Forms of Nitric Oxide. 201-221. DOI: 10.1016/B978-044452236-8/50010-1  0.44
2007 Maron BA, Loscalzo J. The role of platelets in fibrinolysis Platelets. 415-430. DOI: 10.1016/B978-012369367-9/50783-7  0.44
2006 Maitland K, Bridges L, Davis WP, Loscalzo J, Pointer MA. Different effects of angiotensin receptor blockade on end-organ damage in salt-dependent and salt-independent hypertension Circulation. 114: 905-911. PMID 16923758 DOI: 10.1161/CIRCULATIONAHA.106.622316  0.44
2006 Loscalzo J. The NIH budget and the future of biomedical research New England Journal of Medicine. 354: 1665-1667. PMID 16625006 DOI: 10.1056/NEJMp068050  0.44
2006 Handy DE, Loscalzo J. Nitric oxide and posttranslational modification of the vascular proteome: S-nitrosation of reactive thiols Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1207-1214. PMID 16543494 DOI: 10.1161/01.ATV.0000217632.98717.a0  0.44
2006 Loscalzo J. Homocysteine trials - Clear outcomes for complex reasons New England Journal of Medicine. 354: 1629-1632. PMID 16531615 DOI: 10.1056/NEJMe068060  0.44
2006 Handy DE, Hang G, Scolaro J, Metes N, Razaq N, Yang Y, Loscalzo J. Aminoglycosides decrease glutathione peroxidase-1 activity by interfering with selenocysteine incorporation. The Journal of Biological Chemistry. 281: 3382-8. PMID 16354666 DOI: 10.1074/jbc.M511295200  0.44
2006 Kamath AF, Chauhan AK, Kisucka J, Dole VS, Loscalzo J, Handy DE, Wagner DD. Elevated levels of homocysteine compromise blood-brain barrier integrity in mice. Blood. 107: 591-3. PMID 16189268 DOI: 10.1182/blood-2005-06-2506  0.32
2006 Loscalzo J. ATVB in focus: Nitric oxide redux Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 696. DOI: 10.1161/01.ATV.0000209519.12258.74  0.44
2006 Klings ES, Loscalzo J. Secondary pulmonary hypertension Vascular Medicine. 822-831. DOI: 10.1016/B978-0-7216-0284-4.50064-6  0.44
2006 Freedman JE, Loscalzo J. Thrombosis Vascular Medicine. 125-133. DOI: 10.1016/B978-0-7216-0284-4.50014-2  0.44
2006 Ruberg FL, Loscalzo J. Normal mechanisms of hemostasis Vascular Medicine. 61-69. DOI: 10.1016/B978-0-7216-0284-4.50010-5  0.44
2005 Loscalzo J. Clinical trials in cardiovascular medicine in an era of marginal benefit, bias, and hyperbole Circulation. 112: 3026-3029. PMID 16286598 DOI: 10.1161/CIRCULATIONAHA.105.594614  0.44
2005 Leopold JA, Loscalzo J. Oxidative enzymopathies and vascular disease - ATVB in focus Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 1332-1340. PMID 15790928 DOI: 10.1161/01.ATV.0000163846.51473.09  0.44
2005 Yang Y, Loscalzo J. S-nitrosoprotein formation and localization in endothelial cells Proceedings of the National Academy of Sciences of the United States of America. 102: 117-122. PMID 15618409 DOI: 10.1073/pnas.0405989102  0.44
2005 Napoli C, Loscalzo J. New challenges for ACE-inhibitors in vascular diseases Drug Design Reviews Online. 2: 485-493. DOI: 10.2174/156726905774641190  0.44
2005 Feelisch M, Loscalzo J. Nitric Oxide Donors in Cardiovascular Disease Nitric Oxide Donors: For Pharmaceutical and Biological Applications. 283-298. DOI: 10.1002/3527603751.ch11  0.44
2004 Farber HW, Loscalzo J. Pulmonary arterial hypertension. The New England Journal of Medicine. 351: 1655-65. PMID 15483284 DOI: 10.1056/NEJMra035488  0.44
2004 Loscalzo J. L-arginine and atherothrombosis Journal of Nutrition. 134. PMID 15465788  0.44
2004 Faxon DP, Fuster V, Libby P, Beckman JA, Hiatt WR, Thompson RW, Topper JN, Annex BH, Rundback JH, Fabunmi RP, Robertson RM, Loscalzo J. Atherosclerotic Vascular Disease Conference: Writing Group III: pathophysiology. Circulation. 109: 2617-25. PMID 15173044 DOI: 10.1161/01.CIR.0000128520.37674.EF  0.44
2004 Faxon DP, Creager MA, Smith SC, Pasternak RC, Olin JW, Bettmann MA, Criqui MH, Milani RV, Loscalzo J, Kaufman JA, Jones DW, Pearce WH. Atherosclerotic Vascular Disease Conference: Executive summary: Atherosclerotic Vascular Disease Conference proceeding for healthcare professionals from a special writing group of the American Heart Association. Circulation. 109: 2595-604. PMID 15173041 DOI: 10.1161/01.CIR.0000128517.52533.DB  0.44
2004 Bierl C, Voetsch B, Jin RC, Handy DE, Loscalzo J. Determinants of human plasma glutathione peroxidase (GPx-3) expression. The Journal of Biological Chemistry. 279: 26839-45. PMID 15096516 DOI: 10.1074/jbc.M401907200  0.32
2004 Napoli C, Loscalzo J. Nitric Oxide and Other Novel Therapies for Pulmonary Hypertension Journal of Cardiovascular Pharmacology and Therapeutics. 9: 1-8. PMID 15094962  0.44
2004 Voetsch B, Benke KS, Panhuysen CI, Damasceno BP, Loscalzo J. The combined effect of paraoxonase promoter and coding region polymorphisms on the risk of arterial ischemic stroke among young adults. Archives of Neurology. 61: 351-6. PMID 15023811 DOI: 10.1001/archneur.61.3.351  0.44
2004 Voetsch B, Loscalzo J. Genetics of thrombophilia: Impact on atherogenesis Current Opinion in Lipidology. 15: 129-143. PMID 15017356 DOI: 10.1097/00041433-200404000-00006  0.44
2004 Heydrick SJ, Weiss N, Thomas SR, Cap AP, Pimentel DR, Loscalzo J, Keaney JF. L-Homocysteine and L-homocystine stereospecifically induce endothelial nitric oxide synthase-dependent lipid peroxidation in endothelial cells. Free Radical Biology & Medicine. 36: 632-40. PMID 14980706 DOI: 10.1016/j.freeradbiomed.2003.12.001  0.44
2004 Loscalzo J. Ozone - From Environmental Pollutant to Atherogenic Determinant New England Journal of Medicine. 350: 834-835. PMID 14973208 DOI: 10.1056/NEJMcibr033352  0.44
2004 Jain M, Cui L, Brenner DA, Wang B, Handy DE, Leopold JA, Loscalzo J, Apstein CS, Liao R. Increased myocardial dysfunction after ischemia-reperfusion in mice lacking glucose-6-phosphate dehydrogenase. Circulation. 109: 898-903. PMID 14757696 DOI: 10.1161/01.CIR.0000112605.43318.CA  0.32
2004 Loscalzo J. Stem cells and regeneration of the cardiovascular system: Facts, fictions, and uncertainties Blood Cells, Molecules, and Diseases. 32: 97-99. PMID 14757421 DOI: 10.1016/j.bcmd.2003.09.022  0.44
2004 Jones JE, Walker JL, Song Y, Weiss N, Cardoso WV, Tuder RM, Loscalzo J, Zhang YY. Effect of 5-lipoxygenase on the development of pulmonary hypertension in rats. American Journal of Physiology. Heart and Circulatory Physiology. 286: H1775-84. PMID 14726295 DOI: 10.1152/ajpheart.00281.2003  0.44
2004 Voetsch B, Loscalzo J. Genetic Determinants of Arterial Thrombosis Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 216-229. PMID 14615395 DOI: 10.1161/01.ATV.0000107402.79771.fc  0.44
2004 Loscalzo J. The eagle's view, or how to use this journal Circulation. 110: 3. DOI: 10.1161/01.CIR.0000134308.18456.81  0.44
2004 Loscalzo J. Session V: Therapeutic strategies and supplementation - Discussion summary Journal of Nutrition. 134.  0.44
2003 Loscalzo J. The evolution of the discipline of vascular biology: From systems physiology to molecular biology to molecular systems Circulation Research. 93: 583-585. PMID 14525918 DOI: 10.1161/01.RES.0000095381.50007.D1  0.44
2003 Walford G, Loscalzo J. Nitric oxide in vascular biology Journal of Thrombosis and Haemostasis. 1: 2112-2118. PMID 14521592 DOI: 10.1046/j.1538-7836.2003.00345.x  0.44
2003 Loscalzo J. Oxidant stress: A key determinant of atherothrombosis Biochemical Society Transactions. 31: 1059-1061. PMID 14505479  0.44
2003 Leopold JA, Loscalzo J. Organic nitrate tolerance and endothelial dysfunction: Role of folate therapy Minerva Cardioangiologica. 51: 349-359. PMID 12900717  0.44
2003 Loscalzo J. Proteomics in cardiovascular biology and medicine Circulation. 108: 380-383. PMID 12885729 DOI: 10.1161/01.CIR.0000079867.56212.17  0.44
2003 Jain M, Brenner DA, Cui L, Lim CC, Wang B, Pimentel DR, Koh S, Sawyer DB, Leopold JA, Handy DE, Loscalzo J, Apstein CS, Liao R. Glucose-6-phosphate dehydrogenase modulates cytosolic redox status and contractile phenotype in adult cardiomyocytes. Circulation Research. 93: e9-16. PMID 12829617 DOI: 10.1161/01.RES.0000083489.83704.76  0.32
2003 Handy DE, Loscalzo J. Homocysteine and atherothrombosis: Diagnosis and treatment Current Atherosclerosis Reports. 5: 276-283. PMID 12793968  0.44
2003 Loscalzo J. Functional polymorphisms in a candidate gene for atherothrombosis: Unraveling the complex fabric of a polygenic phenotype Journal of the American College of Cardiology. 41: 946-948. PMID 12651038 DOI: 10.1016/S0735-1097(02)03010-3  0.44
2003 Loscalzo J. Adverse effects of supplemental L-arginine in atherosclerosis: Consequences of methylation stress in a complex catabolism? Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 3-5. PMID 12524215 DOI: 10.1161/01.ATV.0000040860.71626.9D  0.44
2003 Freedman JE, Loscalzo J. Nitric oxide and its relationship to thrombotic disorders Journal of Thrombosis and Haemostasis. 1: 1183-1188. DOI: 10.1046/j.1538-7836.2003.00180.x  0.44
2002 Willoughby S, Holmes A, Loscalzo J. Platelets and cardiovascular disease European Journal of Cardiovascular Nursing. 1: 273-288. PMID 14622657 DOI: 10.1016/S1474-5151(02)00038-5  0.44
2002 Loscalzo J. Oxidative stress in endothelial cell dysfunction and thrombosis Pathophysiology of Haemostasis and Thrombosis. 32: 359-360. PMID 13679676 DOI: 10.1159/000073600  0.44
2002 Napoli C, Lerman LO, de Nigris F, Loscalzo J, Ignarro LJ. Glycoxidized low-density lipoprotein downregulates endothelial nitricoxide synthase in human coronary cells. Journal of the American College of Cardiology. 40: 1515-22. PMID 12392844 DOI: 10.1016/S0735-1097(02)02306-9  0.44
2002 Franciosa JA, Taylor AL, Cohn JN, Yancy CW, Ziesche S, Olukotun A, Ofili E, Ferdinand K, Loscalzo J, Worcel M. African-American Heart Failure Trial (A-HeFT): rationale, design, and methodology. Journal of Cardiac Failure. 8: 128-35. PMID 12140804 DOI: 10.1054/jcaf.2002.124730  0.44
2002 Vita JA, Loscalzo J. Shouldering the risk factor burden: Infection, atherosclerosis, and the vascular endothelium Circulation. 106: 164-166. PMID 12105150 DOI: 10.1161/01.CIR.0000023452.26135.34  0.44
2002 Voetsch B, Benke KS, Damasceno BP, Siqueira LH, Loscalzo J. Paraoxonase 192 Gln-->Arg polymorphism: an independent risk factor for nonfatal arterial ischemic stroke among young adults. Stroke; a Journal of Cerebral Circulation. 33: 1459-64. PMID 12052975 DOI: 10.1161/01.STR.0000016928.60995.BD  0.44
2002 Freedman JE, Loscalzo J. Platelet-monocyte aggregates: Bridging thrombosis and inflammation Circulation. 105: 2130-2132. PMID 11994242 DOI: 10.1161/01.CIR.0000017140.26466.F5  0.44
2002 Sawyer DB, Loscalzo J. Myocardial hibernation: restorative or preterminal sleep? Circulation. 105: 1517-9. PMID 11927510 DOI: 10.1161/01.CIR.0000014689.12415.89  0.44
2002 Forgione MA, Weiss N, Heydrick S, Cap A, Klings ES, Bierl C, Eberhardt RT, Farber HW, Loscalzo J. Cellular glutathione peroxidase deficiency and endothelial dysfunction American Journal of Physiology - Heart and Circulatory Physiology. 282: H1255-H1261. PMID 11893559 DOI: 10.1152/ajpheart.00598.2001  0.44
2002 Loscalzo J. Perspective: Homocysteine and dementias New England Journal of Medicine. 346: 466-468. PMID 11844846 DOI: 10.1056/NEJM200202143460702  0.44
2002 Ignarro LJ, Napoli C, Loscalzo J. Nitric oxide donors and cardiovascular agents modulating the bioactivity of nitric oxide: An overview Circulation Research. 90: 21-28. PMID 11786514 DOI: 10.1161/hh0102.102330  0.44
2001 Zhang YY, Loscalzo J. Detection of nitrosated proteins Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. PMID 23045025  0.44
2001 Battinelli E, Willoughby SR, Foxall T, Valeri CR, Loscalzo J. Induction of platelet formation from megakaryocytoid cells by nitric oxide Proceedings of the National Academy of Sciences of the United States of America. 98: 14458-14463. PMID 11734646 DOI: 10.1073/pnas.241427398  0.44
2001 Loscalzo J. An experiment of nature: Genetic L-arginine deficiency and NO insufficiency Journal of Clinical Investigation. 108: 663-664. PMID 11544270 DOI: 10.1172/JCI200113848  0.44
2001 Loscalzo J. Folate and nitrate-induced endothelial dysfunction: A simple treatment for a complex pathobiology Circulation. 104: 1086-1088. PMID 11535558  0.44
2001 Upchurch GR, Goodman DG, Willoughby SR, Zhang YY, Welch GN, Freedman JE, Ye S, Costello CE, Loscalzo J. Heparin reacts with and inactivates nitric oxide Journal of Cardiovascular Pharmacology and Therapeutics. 6: 163-173. PMID 11509923 DOI: 10.1177/107424840100600208  0.44
2001 Loscalzo J. Salt-sensitive hypertension and inducible nitric oxide synthase: Form-function dichotomy of a coding region mutation, Mutatis Mutandis Circulation Research. 89: 292-294. PMID 11509443  0.44
2001 Loscalzo J. Inducible NO synthesis in the vasculature: Molecular context defines physiological response Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 1259-1260. PMID 11498449  0.44
2001 Loscalzo J. Genetic clues to the cause of primary pulmonary hypertension New England Journal of Medicine. 345: 367-371. PMID 11484696 DOI: 10.1056/NEJM200108023450511  0.44
2001 Loscalzo J. Nitric oxide insufficiency, platelet activation, and arterial thrombosis Circulation Research. 88: 756-762. PMID 11325866  0.44
2001 Loscalzo J. The tangled web of heart failure: A complex network of surrogates and correlates Journal of Cardiovascular Electrophysiology. 12: 301-302. PMID 11291802  0.44
2001 Loscalzo J. Resolution of platelet-rich thrombi in essential thrombocythemia: Mechanisms, risks, and benefits of antiplatelet therapy Mayo Clinic Proceedings. 76: 356-357.  0.44
2000 Leopold JA, Loscalzo J. Clinical importance of understanding vascular biology Cardiology in Review. 8: 115-123. PMID 11174883  0.44
2000 Leopold JA, Loscalzo J. Cyclic strain modulates resistance to oxidant stress by increasing G6PDH expression in smooth muscle cells American Journal of Physiology - Heart and Circulatory Physiology. 279. PMID 11045985  0.44
2000 Battinelli E, Loscalzo J. Nitric oxide induces apoptosis in megakaryocytic cell lines Blood. 95: 3451-3459. PMID 10828028  0.44
2000 Yang Y, Loscalzo J. Regulation of tissue factor expression in human microvascular endothelial cells by nitric oxide Circulation. 101: 2144-2148. PMID 10801753  0.44
2000 Loscalzo J. What we know and don't know about L-arginine and NO Circulation. 101: 2126-2129. PMID 10801749  0.44
2000 Awtry EH, Loscalzo J. Aspirin Circulation. 101: 1206-1218. PMID 10715270 DOI: 10.1016/B978-012369367-9/50822-3  0.44
2000 Loscalzo J. Vascular matrix and vein graft failure: Is the message in the medium? Circulation. 101: 221-223. PMID 10645913  0.44
2000 Loscalzo J. Key references: Homocysteine and atherothrombotic vascular disease Journal of Thrombosis and Thrombolysis. 9: 125-126. PMID 10590207 DOI: 10.1023/A:1018606500093  0.44
2000 Forgione MA, Loscalzo J. Oxidant stress as a critical determinant of endothelial function Drug News and Perspectives. 13: 523-529. DOI: 10.1358/dnp.2000.13.9.858480  0.44
1999 Farber HW, Loscalzo J. Prothrombotic mechanisms in primary pulmonary hypertension Journal of Laboratory and Clinical Medicine. 134: 561-566. PMID 10595782 DOI: 10.1016/S0022-2143(99)90094-X  0.44
1999 Price DT, Loscalzo J. Cellular adhesion molecules and atherogenesis American Journal of Medicine. 107: 85-97. PMID 10403357 DOI: 10.1016/S0002-9343(99)00153-9  0.44
1999 Biegelsen ES, Loscalzo J. Endothelial function and atherosclerosis Coronary Artery Disease. 10: 241-256. PMID 10376203  0.44
1998 Welch GN, Loscalzo J. Homocysteine and atherothrombosis New England Journal of Medicine. 338: 1042-1043. PMID 9535670 DOI: 10.1056/NEJM199804093381507  0.44
1997 Leopold JA, Loscalzo J. New developments in nitrosovasodilator therapy Vascular Medicine. 2: 190-202. PMID 9546968  0.44
1997 Upchurch GR, Loscalzo J, Banes AJ. Changes in the amplitude of cyclic lead biphasically modulate endothelial cell DNA synthesis and division Vascular Medicine. 2: 19-24. PMID 9546945 DOI: 10.1177/1358863X9700200104  0.44
1997 Zhao Z, Francis CE, Welch G, Loscalzo J, Ravid K. Reduced glutathione prevents nitric oxide-induced apoptosis in vascular smooth muscle cells Biochimica Et Biophysica Acta - Molecular Cell Research. 1359: 143-152. PMID 9409811 DOI: 10.1016/S0167-4889(97)00093-1  0.44
1997 Moraes D, Loscalzo J. Pulmonary hypertension: newer concepts in diagnosis and management Clinical Cardiology. 20: 676-682. PMID 9259160  0.44
1997 Loscalzo J. Nitric oxide binding and the adverse effects of cell-free hemoglobins: what makes us different from earthworms The Journal of Laboratory and Clinical Medicine. 129: 580-583. PMID 9178723  0.44
1997 Sherman DL, Loscalzo J. Endothelial dysfunction and cardiovascular disease Cardiologia (Rome, Italy). 42: 177-187. PMID 9090161  0.44
1997 Loscalzo J. The narrow therapeutic index of thrombin inhibition: Implications for newer antithrombotic therapies Journal of Thrombosis and Thrombolysis. 4: 315-316. DOI: 10.1023/A:1008824728228  0.44
1996 Loscalzo J. The macrophage and fibrinolysis Seminars in Thrombosis and Hemostasis. 22: 503-506. PMID 9122715  0.44
1996 Dobroski DR, Loscalzo J. Thrombotic risk factors for atherosclerosis Coronary Artery Disease. 7: 919-932. PMID 9116935  0.44
1996 Keaney JF, Hare JM, Balligand JL, Loscalzo J, Smith TW, Colucci WS. Inhibition of nitric oxide synthase augments myocardial contractile responses to beta-adrenergic stimulation. The American Journal of Physiology. 271: H2646-52. PMID 8997327 DOI: 10.1152/ajpheart.1996.271.6.H2646  0.44
1996 Philippides GJ, Loscalzo J. Potential advantages of direct-acting thrombin inhibitors Coronary Artery Disease. 7: 497-507. PMID 8913677  0.44
1996 Michelson AD, Barnard MR, Hechtman HB, MacGregor H, Connolly RJ, Loscalzo J, Valeri CR. In vivo tracking of platelets: circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function. Proceedings of the National Academy of Sciences of the United States of America. 93: 11877-82. PMID 8876231 DOI: 10.1073/pnas.93.21.11877  0.44
1996 Jackson TS, Lerner E, Weisbrod RM, Tajima M, Loscalzo J, Keaney JF. Vasodilatory properties of recombinant maxadilan. The American Journal of Physiology. 271: H924-30. PMID 8853326 DOI: 10.1152/ajpheart.1996.271.3.H924  0.44
1996 Loscalzo J. Thrombin inhibitors in fibrinolysis: A Hobson's choice of alternatives Circulation. 94: 863-865. PMID 8790015  0.44
1996 Loscalzo J. The oxidant stress of hyperhomocyst(e)inemia The Journal of Clinical Investigation. 98: 5-7. PMID 8690803  0.44
1996 Zhang YY, Loscalzo J. [4] Nitrosation of proteins Methods in Neurosciences. 31: 41-46. DOI: 10.1016/S1043-9471(96)80007-3  0.44
1996 Loscalzo J. Nitric oxide and restenosis Clinical and Applied Thrombosis/Hemostasis. 2: 7-10.  0.44
1995 Leopold JA, Loscalzo J. Platelet activation by fibrinolytic agents: A potential mechanism for resistance to thrombolysis and reocclusion after successful thrombolysis Coronary Artery Disease. 6: 923-929. PMID 8723013  0.44
1995 Levy AP, Levy NS, Loscalzo J, Calderone A, Takahashi N, Yeo KT, Koren G, Colucci WS, Goldberg MA. Regulation of vascular endothelial growth factor in cardiac myocytes. Circulation Research. 76: 758-66. PMID 7728992 DOI: 10.1161/01.RES.76.5.758  0.44
1995 Nanji AA, Greenberg SS, Tahan SR, Fogt F, Loscalzo J, Hossein Sadrzadeh SM, Xie J, Stamler JS. Nitric oxide production in experimental alcoholic liver disease in the rat: Role in protection from injury Gastroenterology. 109: 899-907. PMID 7657120 DOI: 10.1016/0016-5085(95)90400-X  0.44
1995 Loscalzo J. Endothelial injury, vasoconstriction, and its prevention Texas Heart Institute Journal. 22: 180-184. PMID 7647603  0.44
1995 Loscalzo J, Welch G. Nitric oxide and its role in the cardiovascular system Progress in Cardiovascular Diseases. 38: 87-104. PMID 7568906 DOI: 10.1016/S0033-0620(05)80001-5  0.44
1995 Schubert PJ, Loscalzo J. Antithrombotic therapy Comprehensive Therapy. 21: 344-350. PMID 7554810  0.44
1995 Loscalzo J. Nitric oxide and vascular disease New England Journal of Medicine. 333: 251-253. PMID 7540723 DOI: 10.1056/NEJM199507273330410  0.44
1995 Hare JM, Keaney JF, Balligand JL, Loscalzo J, Smith TW, Colucci WS. Role of nitric oxide in parasympathetic modulation of beta-adrenergic myocardial contractility in normal dogs. The Journal of Clinical Investigation. 95: 360-6. PMID 7529262 DOI: 10.1172/JCI117664  0.44
1995 Simon DI, Stamler JS, Loh E, Loscalzo J, Francis SA, Creager MA. Effect of nitric oxide synthase inhibition on bleeding time in humans Journal of Cardiovascular Pharmacology. 26: 339-342. PMID 7475061 DOI: 10.1097/00005344-199508000-00022  0.44
1994 Keaney JF, Puyana JC, Francis S, Loscalzo JF, Stamler JS, Loscalzo J. Methylene blue reverses endotoxin-induced hypotension Circulation Research. 74: 1121-1125. PMID 8187278 DOI: 10.1161/01.RES.74.6.1121  0.44
1994 Rabbani LRE, Loscalzo J. Recent observations on the role of hemostatic determinants in the development of the atherothrombotic plaque Atherosclerosis. 105: 1-7. PMID 8155083 DOI: 10.1016/0021-9150(94)90002-7  0.44
1994 Welch G, Loscalzo J. Nitric oxide and the cardiovascular system Journal of Cardiac Surgery. 9: 361-371. PMID 8054733  0.44
1994 Loh E, Stamler JS, Hare JM, Loscalzo J, Colucci WS. Cardiovascular effects of inhaled nitric oxide in patients with left ventricular dysfunction Circulation. 90: 2780-2785. PMID 7994821 DOI: 10.1161/01.CIR.90.6.2780  0.44
1994 Loscalzo J, Vita JA. Ischemia, hyperemia, exercise, and nitric oxide: Complex physiology and complex molecular adaptations Circulation. 90: 2556-2559. PMID 7955218  0.44
1994 Slivka A, Chuttani R, Carr-Locke DL, Kobzik L, Bredt DS, Loscalzo J, Stamler JS. Inhibition of sphincter of Oddi function by the nitric oxide carrier S-nitroso-N-acetylcysteine in rabbits and humans. The Journal of Clinical Investigation. 94: 1792-8. PMID 7525649 DOI: 10.1172/JCI117527  0.44
1994 Jaraki O, Strauss WE, Francis S, Loscalzo J, Stamler JS. Antiplatelet effects of a novel antianginal agent, nicorandil Journal of Cardiovascular Pharmacology. 23: 24-56. PMID 7511731 DOI: 10.1097/00005344-199401000-00024  0.44
1994 Gaston B, Drazen JM, Loscalzo J, Stamler JS. The biology of nitrogen oxides in the airways American Journal of Respiratory and Critical Care Medicine. 149: 538-551. PMID 7508323 DOI: 10.1164/ajrccm.149.2.7508323  0.44
1994 Burchenal JEB, Loscalzo J. Endothelial dysfunction and pulmonary hypertension Primary Cardiology. 20: 28-29.  0.44
1993 Ouimet H, Loscalzo J. Reciprocating autocatalytic interactions between platelets and the activation system Thrombosis Research. 70: 355-364. PMID 8397449 DOI: 10.1016/0049-3848(93)90077-2  0.44
1993 Simon DI, Stamler JS, Jaraki O, Keaney JF, Osborne JA, Francis SA, Singel DJ, Loscalzo J. Antiplatelet properties of protein S-nitrosothiols derived from nitric oxide and endothelium-derived relaxing factor. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology / American Heart Association. 13: 791-9. PMID 8388713  0.44
1993 Stamler JS, Osborne JA, Jaraki O, Rabbani LE, Mullins M, Singel D, Loscalzo J. Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen. The Journal of Clinical Investigation. 91: 308-18. PMID 8380812 DOI: 10.1172/JCI116187  0.44
1993 Sharma GVRK, Lapsley D, Vita JA, Sharma S, Coccio E, Adelman B, Loscalzo J. Usefulness and tolerability of Hirulog, a direct thrombin-inhibitor, in unstable angina pectoris The American Journal of Cardiology. 72: 1357-1360. PMID 8256726 DOI: 10.1016/0002-9149(93)90179-G  0.44
1993 Gaston B, Reilly J, Drazen JM, Fackler J, Ramdev P, Arnelle D, Mullins ME, Sugarbaker DJ, Chee C, Singel DJ, Loscalzo J, Stamler JS. Endogenous nitrogen oxides and bronchodilator S-nitrosothiols in human airways Proceedings of the National Academy of Sciences of the United States of America. 90: 10957-10961. PMID 8248198  0.44
1993 Loscalzo J. The induction of cellular interactions in atherogenesis and their modulation Biochemical Society Transactions. 21: 656-659. PMID 8135929  0.44
1993 Rabbani LE, Loscalzo J. Atherothrombotic insights into secondary prevention after acute myocardial infarction Canadian Journal of Cardiology. 9: 739-747. PMID 7903593  0.44
1993 Rovin JD, Stamler JS, Loscalzo J, Folts JD. Sodium nitroprusside, an endothelium-derived relaxing factor congener, increases platelet cyclic gmp levels and inhibits epinephrine-exacerbated in vivo platelet thrombus formation in stenosed canine coronary arteries Journal of Cardiovascular Pharmacology. 22: 626-631. PMID 7505366 DOI: 10.1097/00005344-199310000-00017  0.44
1993 Loscalzo J, Sniderman A. Cardiovascular disease and hyperlipidaemia Current Opinion in Lipidology. 4: 273-276.  0.44
1992 Loscalzo J, Rocco TP. Imaging arterial thrombi: An elusive goal Circulation. 85: 382-385. PMID 1728477  0.44
1992 Loscalzo J. Endothelial dysfunction in pulmonary hypertension New England Journal of Medicine. 327: 117-119. PMID 1603118  0.44
1992 Scharfstein J, Loscalzo J. Molecular approaches to antithrombotic therapy Hospital Practice. 27: 77-86. PMID 1577892  0.44
1992 Loscalzo J. Antiplatelet and antithrombotic effects of organic nitrates The American Journal of Cardiology. 70. PMID 1529922 DOI: 10.1016/0002-9149(92)90590-U  0.44
1992 Stamler JS, Loscalzo J. Capillary zone electrophoretic detection of biological thiols and their S-nitrosated derivatives Analytical Chemistry. 64: 779-785. PMID 1524223  0.44
1992 Loscalzo J, Handin RI. Platelet glycocalicin Methods in Enzymology. 215: 289-294. PMID 1435328 DOI: 10.1016/0076-6879(92)15071-J  0.44
1992 Loscalzo J. The relation between atherosclerosis and thrombosis Circulation. 86. PMID 1424055  0.44
1992 Stamler JS, Simon DI, Osborne JA, Mullins ME, Jaraki O, Michel T, Singel DJ, Loscalzo J. S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds. Proceedings of the National Academy of Sciences of the United States of America. 89: 444-8. PMID 1346070  0.44
1992 Stamler JS, Simon DI, Jaraki O, Osborne JA, Francis S, Mullins M, Singel D, Loscalzo J. S-nitrosylation of tissue-type plasminogen activator confers vasodilatory and antiplatelet properties on the enzyme. Proceedings of the National Academy of Sciences of the United States of America. 89: 8087-91. PMID 1325644 DOI: 10.1073/pnas.89.17.8087  0.44
1992 Stamler JS, Loscalzo J. Endothelium-derived relaxing factor modulates the atherothrombogenic effects of homocysteine Journal of Cardiovascular Pharmacology. 20. PMID 1282970  0.44
1992 Stamler JS, Singel DJ, Loscalzo J. Biochemistry of nitric oxide and its redox-activated forms Science. 258: 1898-1902. PMID 1281928  0.44
1992 Mullins ME, Stamler JS, Osborne JA, Loscalzo J, Singel DJ. EPR spectroscopic characterization of biological thiyl radicals as PBN spin-trap adducts Applied Magnetic Resonance. 3: 1021-1032. DOI: 10.1007/BF03166170  0.44
1992 Bilheimer D, Loscalzo J. Cardiovascular disease: Hyperlipidaemia and coagulation Current Opinion in Lipidology. 3: 253-256.  0.44
1991 Stamler JS, Loscalzo J. The antiplatelet effects of organic nitrates and related nitroso compounds in vitro and in vivo and their relevance to cardiovascular disorders Journal of the American College of Cardiology. 18: 1529-1536. PMID 1939957 DOI: 10.1016/0735-1097(91)90686-4  0.44
1991 Ezratty AM, Loscalzo J. New approaches to antiplatelet therapy Blood Coagulation &Amp; Fibrinolysis : An International Journal in Haemostasis and Thrombosis. 2: 317-327. PMID 1893063  0.44
1991 Newburger JW, Burns JC, Beiser AS, Loscalzo J. Altered lipid profile after Kawasaki syndrome Circulation. 84: 625-631. PMID 1860206 DOI: 10.1161/01.CIR.84.2.625  0.44
1991 Stamler JS, Vaughan DE, Loscalzo J. Immunosuppressive therapy and lipoprotein abnormalities after cardiac transplantation The American Journal of Cardiology. 68: 389-391. PMID 1858681 DOI: 10.1016/0002-9149(91)90837-B  0.44
1991 Pasche B, Loscalzo J. Platelets and fibrinolysis Platelets. 2: 125-134. DOI: 10.3109/09537109109006022  0.44
1991 Stamler JS, Loscalzo J. The antithrombotic effects of organic nitrates Trends in Cardiovascular Medicine. 1: 346-353. DOI: 10.1016/1050-1738(91)90073-N  0.44
1991 Vaughan DE, Loscalzo J. New directions in thrombolytic therapy. Molecular mutants and biochemical conjugates Trends in Cardiovascular Medicine. 1: 36-39. DOI: 10.1016/1050-1738(91)90057-L  0.44
1991 Rabbani LE, Loscalzo J. The effects of hyperlipidemia and atherosclerosis on endothelial function and vascular reactivity Current Opinion in Lipidology. 2: 259-265.  0.44
1990 Cooke JP, Stamler J, Andon N, Davies PF, McKinley G, Loscalzo J. Flow stimulates endothelial cells to release a nitrovasodilator that is potentiated by reduced thiol American Journal of Physiology - Heart and Circulatory Physiology. 259. PMID 2396689 DOI: 10.1152/ajpheart.1990.259.3.H804  0.44
1990 Mendelsohn ME, Loscalzo J. Sudden cardiac death (II) New England Journal of Medicine. 322: 271-272. PMID 2294457 DOI: 10.1056/NEJM199001253220416  0.44
1990 Loscalzo J. Regression of coronary atherosclerosis New England Journal of Medicine. 323: 1337-1339. PMID 2215620  0.44
1990 Creager MA, Cooke JP, Mendelsohn ME, Gallagher SJ, Coleman SM, Loscalzo J, Dzau VJ. Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans. The Journal of Clinical Investigation. 86: 228-34. PMID 2195060 DOI: 10.1172/JCI114688  0.44
1990 Loscalzo J. An overview of thrombolytic agents Chest. 97. PMID 2182306  0.44
1990 Kuo P, Weinfeld M, Loscalzo J. Effect of membrane fatty acyl composition on LDL metabolism in Hep G2 hepatocytes Biochemistry. 29: 6626-6632. PMID 2168736 DOI: 10.1021/bi00480a011  0.44
1990 Simon DI, Loscalzo J. Lipoprotein(a) and coronary heart disease in patients with familial hypercholesterolemia (I) New England Journal of Medicine. 323: 1773-1774. PMID 2147230 DOI: 10.1056/nejm199012203232514  0.44
1990 Loscalzo J. Lipoprotein(a). A unique risk factor for atherothrombotic disease Arteriosclerosis. 10: 672-679. PMID 2144959  0.44
1990 Loscalzo J. Molecular biologic modification of plasminogen activators. An artful science: Editorial comment Circulation. 82: 1062-1063. PMID 2118430 DOI: 10.1161/01.CIR.82.3.1062  0.44
1990 Rudd MA, George D, Johnstone MT, Moore RT, Collins L, Rabbani LE, Loscalzo J. Effect of thrombin inhibition on the dynamics of thrombolysis and on platelet function during thrombolytic therapy Circulation Research. 70: 829-834. PMID 1551206 DOI: 10.1161/01.RES.70.4.829  0.44
1989 Stamler J, Whittemore AD, Loscalzo J. Celiac axis compression syndrome caused by sarcoidosis: An acquired form of the syndrome The American Journal of Medicine. 86: 225-227. PMID 2913788 DOI: 10.1016/0002-9343(89)90275-1  0.44
1989 Loscalzo J. Thrombolysis in the Management of Acute Myocardial Infarction and Unstable Angina Pectoris Drugs. 37: 191-204. PMID 2649355 DOI: 10.2165/00003495-198937020-00006  0.44
1989 Inbal A, Loscalzo J. Glycocalicin binding to von Willebrand factor adsorbed onto collagen-coated or polystyrene surfaces Thrombosis Research. 56: 347-357. PMID 2617474 DOI: 10.1016/0049-3848(89)90247-8  0.44
1989 Stamler J, Mendelsohn ME, Amarante P, Smick D, Andon N, Davies PF, Cooke JP, Loscalzo J. N-acetylcysteine potentiates platelet inhibition by endothelium-derived relaxing factor Circulation Research. 65: 789-795. PMID 2548765 DOI: 10.1161/01.RES.65.3.789  0.44
1989 Stamler JS, Vaughan DE, Loscalzo J. Synergistic disaggregation of platelets by tissue-type plasminogen activator, prostaglandin E1, and nitroglycerin Circulation Research. 65: 796-804. PMID 2504509 DOI: 10.1161/01.RES.65.3.796  0.44
1988 Mendelsohn ME, Loscalzo J. Role of platelets in cholesteryl ester formation by U-937 cells Journal of Clinical Investigation. 81: 62-68. PMID 3335643  0.44
1988 Stamler JS, Creager MA, Loscalzo J, Cooke JP, Parkhouse N, Le Quesne PM. Vascular response in diabetes with neuropathic foot lesions New England Journal of Medicine. 319: 1155. PMID 3173448 DOI: 10.1056/NEJM198810273191712  0.44
1988 Loscalzo J. Structural and kinetic comparison of recombinant human single- and two-chain tissue plasminogen activator Journal of Clinical Investigation. 82: 1391-1397. PMID 3139714  0.44
1988 Loscalzo J, Braunwald E. Tissue plasminogen activator New England Journal of Medicine. 319: 925-931. PMID 3138537  0.44
1988 Goldhaber S, Loscalzo J. UROKINASE VERSUS TISSUE PLASMINOGEN ACTIVATOR IN PULMONARY EMBOLISM The Lancet. 332: 915. PMID 2902375 DOI: 10.1016/S0140-6736(88)92530-5  0.44
1987 Loscalzo J, Vaughan DE. Tissue plasminogen activator promotes platelet disaggregation in plasma Journal of Clinical Investigation. 79: 1749-1755. PMID 2438305  0.44
1986 Loscalzo J. Paradoxical embolism: Clinical presentation, diagnostic strategies, and therapeutic options American Heart Journal. 112: 141-145. PMID 3728270 DOI: 10.1016/0002-8703(86)90692-7  0.44
1986 Loscalzo J, Freedman J. Purification and characterization of human platelet glutathione-S-transferase Blood. 67: 1595-1599. PMID 3085745  0.44
1986 Loscalzo J, Rabkin D. The interaction of Tb3+ with the human platelet surface Archives of Biochemistry and Biophysics. 249: 237-242. PMID 2943224 DOI: 10.1016/0003-9861(86)90579-5  0.44
1986 Loscalzo J, Antman E. Artificial cardiac pacemakers: Current concepts Journal of Critical Care. 1: 174-190.  0.44
1985 Loscalzo J. N-acetylcysteine potentiates inhibition of platelet aggregation by nitroglycerin Journal of Clinical Investigation. 76: 703-708. PMID 2863286  0.44
1984 Lipton SA, Hickey WF, Morris JH, Loscalzo J. Candidal infection in the central nervous system. The American Journal of Medicine. 76: 101-8. PMID 6691350 DOI: 10.1016/0002-9343(84)90757-5  0.44
1984 Shorey J, Bhardwaj N, Loscalzo J. Acute Wernicke's encephalopathy after intravenous infusion of high-dose nitroglycerin. Annals of Internal Medicine. 101: 500. PMID 6433765 DOI: 10.7326/0003-4819-101-4-500  0.44
1984 Loscalzo J, Handin RI. Conformational domains and structural transitions of human von Willebrand protein Biochemistry. 23: 3880-3886. PMID 6333249  0.44
1979 Loscalzo J, Daniele RP. Modulation of β-adrenergic receptors in alveolar macrophage membranes: The effect of phagocytosis and adherence American Review of Respiratory Disease. 119: 74.  0.44
1976 Loscalzo J, Reed GH. Spectroscopic studies of actin-metal-nucleotide complexes Biochemistry. 15: 5407-5413. PMID 187216  0.44
1975 Loscalzo J, Reed GH, Weber A. Conformational change and cooperativity in actin filaments free of tropomyosin Proceedings of the National Academy of Sciences of the United States of America. 72: 3412-3415. PMID 1103145 DOI: 10.1073/pnas.72.9.3412  0.44
1973 Loscalzo J, Kallen RG, Voet D. The x ray structure of thiazolidine-4-carboxylic acid. Archives of Biochemistry and Biophysics. 157: 426-30. PMID 4730802 DOI: 10.1016/0003-9861(73)90658-9  0.44
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