Longqin Hu - Publications

Affiliations: 
Chemistry, Pharmaceutical Rutgers University, New Brunswick, United States 
Area:
Pharmaceutical Chemistry

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Year Citation  Score
2018 Yang J, Hu L. Immunomodulators targeting the PD-1/PD-L1 protein-protein interaction: From antibodies to small molecules. Medicinal Research Reviews. PMID 30215856 DOI: 10.1002/med.21530  1
2018 Yang Y, Albanyan H, Lee S, Aloysius H, Liang JJ, Kholodovych V, Sahota A, Hu L. Design, synthesis, and evaluation of l-cystine diamides as l-cystine crystallization inhibitors for cystinuria. Bioorganic & Medicinal Chemistry Letters. PMID 29571572 DOI: 10.1016/j.bmcl.2018.03.024  0.56
2017 Shen J, Magesh S, Chen L, Hu L, He Y. Enantiomeric characterization and structure elucidation of LH601A using vibrational circular dichroism spectroscopy. Spectrochimica Acta. Part a, Molecular and Biomolecular Spectroscopy. 192: 312-317. PMID 29172127 DOI: 10.1016/j.saa.2017.11.033  0.44
2016 Hu L, Yang Y, Aloysius H, Albanyan H, Yang M, Liang JJ, Yu AC, Shtukenberg AG, Poloni LN, Kholodovych V, Tischfield JA, Goldfarb DS, Ward MD, Sahota A. L-CYSTINE DIAMIDES AS L-CYSTINE CRYSTALLIZATION INHIBITORS FOR CYSTINURIA. Journal of Medicinal Chemistry. PMID 27409142 DOI: 10.1021/acs.jmedchem.6b00647  0.56
2016 Li Q, Yu Y, Kang Y, Xu J, Lin H, Wang X, Pang L, Hu L, Zhang Y, Yang X, Zuo W, Qiu G, Jiang Y, Li C, Wang G. Correlations of Cerebrospinal Fluid/Plasma Fibroblast Growth Factor 21 Ratio with Metabolic Parameters in Chinese Individuals of Normal Weight. Clinical Laboratory. 62: 893-9. PMID 27349016  1
2016 Hu LX, Ying GG, Chen XW, Huang GY, Liu YS, Jiang YX, Pan CG, Tian F, Martin FL. FTIR spectroscopy as a novel approach towards providing effect-based endpoints in duckweed toxicity testing. Environmental Toxicology and Chemistry / Setac. PMID 27328901 DOI: 10.1002/etc.3534  0.32
2016 Hu L, Wu X, Yang J. Mn2C monolayer: a 2D antiferromagnetic metal with high Néel temperature and large spin-orbit coupling. Nanoscale. PMID 27304676 DOI: 10.1039/c6nr02417c  1
2016 Wu S, Jiang Y, Hu L, Sun J, Wan P, Sun L. Size-dependent crystalline fluctuation and growth mechanism of bismuth nanoparticles under electron beam irradiation. Nanoscale. PMID 27271758 DOI: 10.1039/c6nr03328h  1
2016 Hu L, Wang J, Zhu H, Wu X, Zhou L, Song Y, Zhu S, Hao M, Liu C, Fan Y, Wang Y, Li Q. Ischemic postconditioning protects the heart against ischemia-reperfusion injury via neuronal nitric oxide synthase in the sarcoplasmic reticulum and mitochondria. Cell Death & Disease. 7: e2222. PMID 27171264 DOI: 10.1038/cddis.2016.108  0.96
2016 Wu X, Hu L. Design and synthesis of peptide conjugates of phosphoramide mustard as prodrugs activated by prostate-specific antigen. Bioorganic & Medicinal Chemistry. PMID 27156193 DOI: 10.1016/j.bmc.2016.04.035  0.96
2016 Wu X, Xiao L, Peng B, Wang Y, Yang Z, Yao X, Hu L, Lin X. Prokaryotic expression, purification and antigenicity analysis of African swine fever virus pK205R protein. Polish Journal of Veterinary Sciences. 19: 41-48. PMID 27096786 DOI: 10.1515/pjvs-2016-0006  0.6
2016 Gao M, Chen G, Wang H, Xie B, Hu L, Kong Y, Yang G, Tao Y, Han Y, Wu X, Zhang Y, Dai B, Shi J. Therapeutic potential and functional interaction of carfilzomib and vorinostat in T-cell leukemia/lymphoma. Oncotarget. PMID 27074555 DOI: 10.18632/oncotarget.8667  0.36
2016 Wang JZ, Sun HM, Zhang CH, Hu L, Li X, Wu XW. Safety assessment of Maillard reaction products of chicken bone hydrolysate using Sprague-Dawley rats. Food & Nutrition Research. 60: 27827. PMID 27016175  0.6
2016 Zhu Z, Pang B, Iglesias-Bartolome R, Wu X, Hu L, Zhang C, Wang J, Gutkind JS, Wang S. Prevention of irradiation-induced salivary hypofunction by rapamycin in swine parotid glands. Oncotarget. PMID 26958808 DOI: 10.18632/oncotarget.7941  0.96
2016 Qian P, Jiang Y, Wang S, Su KH, Wang J, Hu L, Muzic RF. Affinity and Penalty Jointly Constrained Spectral Clustering With All-Compatibility, Flexibility, and Robustness. Ieee Transactions On Neural Networks and Learning Systems. PMID 26915134 DOI: 10.1109/TNNLS.2015.2511179  0.4
2016 Wu X, Wu C, Wei C, Hu L, Qian J, Cao Y, Ai X, Wang J, Yang H. Highly Crystallized Na2CoFe(CN)6 with Suppressed Lattice Defects as Superior Cathode Material for Sodium-ion Batteries. Acs Applied Materials & Interfaces. PMID 26849278 DOI: 10.1021/acsami.5b12620  0.32
2016 Li YH, Qiu YQ, Xian HX, Shi XL, Lin YM, Chen QC, Jiang M, Jiang YX, Hu LL, Hu QH. [Epidemiologic and etiologic characteristics of diarrheagenic Escherichia coli infection in population in Shenzhen]. Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi. 37: 115-8. PMID 26822657  0.32
2016 Wang J, Wang F, Liu Y, Xu J, Lin H, Jia B, Zuo W, Jiang Y, Hu L, Lin F. Multiple Linear Regression and Artificial Neural Network to Predict Blood Glucose in Overweight Patients. Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association. 124: 34-8. PMID 26797861 DOI: 10.1055/s-0035-1565175  0.52
2016 Zhang C, Zhu Q, He H, Jiang L, Qiang Q, Hu L, Hu G, Jiang Y, Ding X, Lu Y. Erratum to: RIZ1: a potential tumor suppressor in glioma. Bmc Cancer. 16: 26. PMID 26781093 DOI: 10.1186/s12885-016-2067-x  1
2016 Qian P, Jiang Y, Deng Z, Hu L, Sun S, Wang S, Muzic RF. Cluster Prototypes and Fuzzy Memberships Jointly Leveraged Cross-Domain Maximum Entropy Clustering. Ieee Transactions On Cybernetics. 46: 181-93. PMID 26684257 DOI: 10.1109/TCYB.2015.2399351  0.4
2015 Qian X, Chen H, Wu X, Hu L, Huang Q, Jin Y. Interleukin-17 acts as double-edged sword in anti-tumor immunity and tumorigenesis. Cytokine. PMID 26883678 DOI: 10.1016/j.cyto.2015.09.011  0.96
2015 Hu L, Lin X, Nie F, ZexiaoYang, Yao X, Li G, Wu X, Ren M, Wang Y. Simultaneous typing of seven porcine pathogens by multiplex PCR with a GeXP analyser. Journal of Virological Methods. PMID 26706731 DOI: 10.1016/j.jviromet.2015.12.004  0.6
2015 Zhang C, Zhu Q, He H, Jiang L, Qiang Q, Hu L, Hu G, Jiang Y, Ding X, Lu Y. RIZ1: a potential tumor suppressor in glioma. Bmc Cancer. 15: 990. PMID 26690953 DOI: 10.1186/s12885-015-2023-1  1
2015 Chen J, Han X, Fang Z, Cheng F, Zhao B, Lu P, Li J, Dai J, Lacey S, Elspas R, Jiang Y, Liu D, Hu L. Rapid Dissolving-Debonding Strategy for Optically Transparent Paper Production. Scientific Reports. 5: 17703. PMID 26657809 DOI: 10.1038/srep17703  1
2015 Abed DA, Goldstein M, Albanyan H, Jin H, Hu L. Discovery of direct inhibitors of Keap1-Nrf2 protein-protein interaction as potential therapeutic and preventive agents. Acta Pharmaceutica Sinica. B. 5: 285-299. PMID 26579458 DOI: 10.1016/j.apsb.2015.05.008  0.64
2015 Hu L, Wang F, Xu J, Wang X, Lin H, Zhang Y, Yu Y, Wang Y, Pang L, Zhang X, Liu Q, Qiu G, Jiang Y, Xie L, Liu Y. Prediction of liver injury using the BP-ANN model with metabolic parameters in overweight and obese Chinese subjects. International Journal of Clinical and Experimental Medicine. 8: 13359-64. PMID 26550266  1
2015 Wu X, Zhao G, Lin J, Jiang N, Li C, Hu L, Peng X, Xu Q, Wang Q, Li H, Zhang Y. The production mechanism and immunosuppression effect of pulmonary surfactant protein D via toll like receptor 4 signaling pathway in human corneal epithelial cells during Aspergillus fumigatus infection. International Immunopharmacology. PMID 26507163 DOI: 10.1016/j.intimp.2015.10.018  0.96
2015 Chen XJ, Zhang XH, Hu LD, Zhang JQ, Jiang Y, Yang Y, Yan YB. DsCaf1 is involved in environmental stress response of Dunaliella salina. International Journal of Biological Macromolecules. PMID 26454106 DOI: 10.1016/j.ijbiomac.2015.10.015  0.44
2015 Song H, Han Y, Pan C, Deng X, Dai W, Hu L, Jiang C, Yang Y, Cheng Z, Li F, Zhang G, Wu X, Liu W. Activation of Adenosine Monophosphate-activated Protein Kinase Suppresses Neuroinflammation and Ameliorates Bone Cancer Pain: Involvement of Inhibition on Mitogen-activated Protein Kinase. Anesthesiology. PMID 26378398 DOI: 10.1097/ALN.0000000000000856  0.96
2015 Zhou L, Sun CB, Liu C, Fan Y, Zhu HY, Wu XW, Hu L, Li QP. Upregulation of arginase activity contributes to intracellular ROS production induced by high glucose in H9c2 cells. International Journal of Clinical and Experimental Pathology. 8: 2728-36. PMID 26045778  0.6
2015 Zhang C, Qiang Q, Jiang Y, Hu L, Ding X, Lu Y, Hu G. Effects of hypoxia inducible factor-1α on apoptotic inhibition and glucocorticoid receptor downregulation by dexamethasone in AtT-20 cells. Bmc Endocrine Disorders. 15: 24. PMID 26002039 DOI: 10.1186/s12902-015-0017-2  1
2015 Zhao H, Xu L, Su T, Jiang Y, Hu L, Ma F. Melatonin regulates carbohydrate metabolism and defenses against Pseudomonas syringae pv. tomato DC3000 infection in Arabidopsis thaliana. Journal of Pineal Research. 59: 109-19. PMID 25958775 DOI: 10.1111/jpi.12245  1
2015 Xie J, Wu X, Ren H, Wang W, Wang Z, Pan X, Hao X, Tong J, Ma J, Ye Z, Meng G, Zhu Y, Kiryluk K, Kong X, Hu L, et al. COL4A3 mutations cause focal segmental glomerulosclerosis. Journal of Molecular Cell Biology. 7: 184. PMID 25888712 DOI: 10.1093/jmcb/mjv023  0.96
2015 Aloysius H, Hu L. Improving the Specificity of the Prostate-Specific Antigen Substrate Glutaryl-Hyp-Ala-Ser-Chg-Gln as a Promoiety. Chemical Biology & Drug Design. PMID 25777622 DOI: 10.1111/cbdd.12559  0.56
2015 Sullivan JA, Tong JL, Wong M, Kumar A, Sarkar H, Ali S, Hussein I, Zaman I, Meredith EL, Helsby NA, Hu L, Wilkinson SR. Unravelling the role of SNM1 in the DNA repair system of Trypanosoma brucei. Molecular Microbiology. 96: 827-38. PMID 25689597 DOI: 10.1111/mmi.12973  0.64
2015 Aloysius H, Hu L. Targeted prodrug approaches for hormone refractory prostate cancer. Medicinal Research Reviews. 35: 554-85. PMID 25529338 DOI: 10.1002/med.21333  0.56
2015 Wang C, Jiang Y, Li X, Hu L. Thioglucose-bound gold nanoparticles increase the radiosensitivity of a triple-negative breast cancer cell line (MDA-MB-231). Breast Cancer (Tokyo, Japan). 22: 413-20. PMID 24114595 DOI: 10.1007/s12282-013-0496-9  1
2014 Wu XQ, Hu CJ, Zhao L, Geng YY, Pan X, Hu L. [Purgative activity difference and mechanism of raw and processed Rhei Radix et rhizoma]. Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials. 37: 1562-5. PMID 25857153  0.52
2014 Xie J, Wu X, Ren H, Wang W, Wang Z, Pan X, Hao X, Tong J, Ma J, Ye Z, Meng G, Zhu Y, Kiryluk K, Kong X, Hu L, et al. COL4A3 mutations cause focal segmental glomerulosclerosis. Journal of Molecular Cell Biology. 6: 498-505. PMID 25596306 DOI: 10.1093/jmcb/mju040  0.96
2014 Hu L, Zhou L, Wu X, Liu C, Fan Y, Li Q. Hypoxic preconditioning protects cardiomyocytes against hypoxia/reoxygenation injury through AMPK/eNOS/PGC-1α signaling pathway. International Journal of Clinical and Experimental Pathology. 7: 7378-88. PMID 25550773  0.96
2014 Hu L, Han J, Zheng F, Ma H, Chen J, Jiang Y, Jiang H. Early second-trimester serum microRNAs as potential biomarker for nondiabetic macrosomia. Biomed Research International. 2014: 394125. PMID 25405200 DOI: 10.1155/2014/394125  1
2014 Ye L, Wang C, Yu G, Jiang Y, Sun D, Zhang Z, Yu X, Li X, Wei W, Liu P, Cheng J, DU B, Hu L. Bmi-1 induces radioresistance by suppressing senescence in human U87 glioma cells. Oncology Letters. 8: 2601-2606. PMID 25364434 DOI: 10.3892/ol.2014.2606  1
2014 Zhang C, Hu L, Wu X, Hu G, Ding X, Lu Y. A retrospective study on the aetiology, management, and outcome of brain abscess in an 11-year, single-centre study from China. Bmc Infectious Diseases. 14: 311. PMID 24903315 DOI: 10.1186/1471-2334-14-311  0.96
2014 Shao Y, Zhou Y, Hou Y, He J, Hu L, Zhang Y, Jiang Y, Lu W, Liu H. Prognostic implications of SLIT and ROBO1 expression in gallbladder cancer. Cell Biochemistry and Biophysics. 70: 747-58. PMID 24777813 DOI: 10.1007/s12013-014-9976-6  1
2014 Fan L, Hu L, Yang B, Fang X, Gao Z, Li W, Sun Y, Shen Y, Wu X, Shu Y, Gu Y, Wu X, Xu Q. Erlotinib promotes endoplasmic reticulum stress-mediated injury in the intestinal epithelium. Toxicology and Applied Pharmacology. 278: 45-52. PMID 24768708 DOI: 10.1016/j.taap.2014.04.015  0.96
2014 Cheng Y, Tu W, Xiao Q, Chen Y, Hu L, Wu X. Risk of cardiovascular disease in patients on thrice-weekly versus twice-weekly hemodialysis. International Journal of Cardiology. 174: 780-3. PMID 24768378 DOI: 10.1016/j.ijcard.2014.04.052  0.96
2014 Yu X, Jin T, Cui Y, Pu X, Li J, Xu J, Liu G, Jia H, Liu D, Song S, Yu Y, Xie L, Huang R, Ding H, Kou Y, ... ... Hu L, et al. Influenza H7N9 and H9N2 viruses: coexistence in poultry linked to human H7N9 infection and genome characteristics. Journal of Virology. 88: 3423-31. PMID 24403589 DOI: 10.1128/JVI.02059-13  0.96
2014 Chen L, Magesh S, Wang H, Yang CS, Kong AN, Hu L. Design and synthesis of novel iminothiazinylbutadienols and divinylpyrimidinethiones as ARE inducers. Bioorganic & Medicinal Chemistry Letters. 24: 940-3. PMID 24398297 DOI: 10.1016/j.bmcl.2013.12.072  0.44
2014 Lee JH, Lee KR, Su ZY, Boyanapalli SS, Barman DN, Huang MT, Chen L, Magesh S, Hu L, Kong AN. In vitro and in vivo anti-inflammatory effects of a novel 4,6-bis ((E)-4-hydroxy-3-methoxystyryl)-1-phenethylpyrimidine-2(1H)-thione. Chemical Research in Toxicology. 27: 34-41. PMID 24304388 DOI: 10.1021/tx400315u  0.64
2013 Hu LC, Wu X, Yang XD. [Optimization of supercritical fluid extraction of bioactive components in Ligusticum chuanxiong by orthogonal array design]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 38: 3484-8. PMID 24490558  0.96
2013 Jiang Y, Hu L. Peptide conjugates of 4-aminocyclophosphamide as prodrugs of phosphoramide mustard for selective activation by prostate-specific antigen (PSA). Bioorganic & Medicinal Chemistry. 21: 7507-14. PMID 24139844 DOI: 10.1016/j.bmc.2013.09.039  1
2013 Voak AA, Gobalakrishnapillai V, Seifert K, Balczo E, Hu L, Hall BS, Wilkinson SR. An essential type I nitroreductase from Leishmania major can be used to activate leishmanicidal prodrugs. The Journal of Biological Chemistry. 288: 28466-76. PMID 23946481 DOI: 10.1074/jbc.M113.494781  0.64
2013 Chen C, Hu LX, Dong T, Wang GQ, Wang LH, Zhou XP, Jiang Y, Murao K, Lu SQ, Chen JW, Zhang GX. Apoptosis and autophagy contribute to gender difference in cardiac ischemia-reperfusion induced injury in rats. Life Sciences. 93: 265-70. PMID 23827240 DOI: 10.1016/j.lfs.2013.06.019  1
2013 Wang C, Xu Z, Jin G, Hu Z, Dai J, Ma H, Jiang Y, Hu L, Chu M, Cao S, Shen H. Genome-wide analysis of runs of homozygosity identifies new susceptibility regions of lung cancer in Han Chinese. Journal of Biomedical Research. 27: 208-14. PMID 23720676 DOI: 10.7555/JBR.27.20130017  1
2013 Hu L, Magesh S, Chen L, Wang L, Lewis TA, Chen Y, Khodier C, Inoyama D, Beamer LJ, Emge TJ, Shen J, Kerrigan JE, Kong AN, Dandapani S, Palmer M, et al. Discovery of a small-molecule inhibitor and cellular probe of Keap1-Nrf2 protein-protein interaction. Bioorganic & Medicinal Chemistry Letters. 23: 3039-43. PMID 23562243 DOI: 10.1016/j.bmcl.2013.03.013  0.64
2012 Jin G, Ma H, Wu C, Dai J, Zhang R, Shi Y, Lu J, Miao X, Wang M, Zhou Y, Chen J, Li H, Pan S, Chu M, Lu F, ... ... Hu L, et al. Genetic variants at 6p21.1 and 7p15.3 are associated with risk of multiple cancers in Han Chinese. American Journal of Human Genetics. 91: 928-34. PMID 23103227 DOI: 10.1016/j.ajhg.2012.09.009  1
2012 Hu LL, Huang Y, Wang QC, Zou Q, Jiang Y. Benchmark comparison of ab initio microRNA identification methods and software. Genetics and Molecular Research : Gmr. 11: 4525-38. PMID 23096922 DOI: 10.4238/2012.October.17.4  1
2012 Yang Y, Voak A, Wilkinson SR, Hu L. Design, synthesis, and evaluation of potential prodrugs of DFMO for reductive activation. Bioorganic & Medicinal Chemistry Letters. 22: 6583-6. PMID 23031595 DOI: 10.1016/j.bmcl.2012.09.005  0.64
2012 Yang X, Wu X, Hu L, Guo H. [Effect of different solvents on extraction of effective components from Ligusticum chuanxiong]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 37: 1942-5. PMID 23019875  0.96
2012 Duan P, Li S, Ai N, Hu L, Welsh WJ, You G. Potent inhibitors of human organic anion transporters 1 and 3 from clinical drug libraries: discovery and molecular characterization. Molecular Pharmaceutics. 9: 3340-6. PMID 22973893 DOI: 10.1021/mp300365t  0.64
2012 Hu L, Wu C, Zhao X, Heist R, Su L, Zhao Y, Han B, Cao S, Chu M, Dai J, Dong J, Shu Y, Xu L, Chen Y, Wang Y, et al. Genome-wide association study of prognosis in advanced non-small cell lung cancer patients receiving platinum-based chemotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 5507-14. PMID 22872573 DOI: 10.1158/1078-0432.CCR-12-1202  1
2012 Ou F, Li K, Gao Q, Liu D, Li J, Hu L, Wu X, Edmiston EK, Liu Y. An urban neo-poverty population-based quality of life and related social characteristics investigation from northeast China. Plos One. 7: e38861. PMID 22719968 DOI: 10.1371/journal.pone.0038861  0.96
2012 Magesh S, Chen Y, Hu L. Small molecule modulators of Keap1-Nrf2-ARE pathway as potential preventive and therapeutic agents. Medicinal Research Reviews. 32: 687-726. PMID 22549716 DOI: 10.1002/med.21257  0.56
2012 Jia H, Wu XF, Hu LM, Liu PB. [In situ experimental research on natural attenuation of oil pollutants in a gas station]. Huan Jing Ke Xue= Huanjing Kexue / [Bian Ji, Zhongguo Ke Xue Yuan Huan Jing Ke Xue Wei Yuan Hui "Huan Jing Ke Xue" Bian Ji Wei Yuan Hui.]. 33: 163-8. PMID 22452205  0.56
2012 Inoyama D, Chen Y, Huang X, Beamer LJ, Kong AN, Hu L. Optimization of fluorescently labeled Nrf2 peptide probes and the development of a fluorescence polarization assay for the discovery of inhibitors of Keap1-Nrf2 interaction. Journal of Biomolecular Screening. 17: 435-47. PMID 22156223 DOI: 10.1177/1087057111430124  0.56
2012 Hu Y, Tang B, Guo J, Wu X, Sun Q, Shi C, Hu L, Wang C, Wang L, Tan L, Shen L, Yan X, Zhang H. Variant in the 3' region of SNCA associated with Parkinson's disease and serum α-synuclein levels. Journal of Neurology. 259: 497-504. PMID 21853288 DOI: 10.1007/s00415-011-6209-4  0.36
2012 Dong J, Hu Z, Shu Y, Pan S, Chen W, Wang Y, Hu L, Jiang Y, Dai J, Ma H, Jin G, Shen H. Potentially functional polymorphisms in DNA repair genes and non-small-cell lung cancer survival: a pathway-based analysis. Molecular Carcinogenesis. 51: 546-52. PMID 21739480 DOI: 10.1002/mc.20819  1
2011 Jia H, Wu XF, Hu LM, Liu PB. [Research of the natural attenuation capacity of oil pollutants based on in-situ experiment]. Huan Jing Ke Xue= Huanjing Kexue / [Bian Ji, Zhongguo Ke Xue Yuan Huan Jing Ke Xue Wei Yuan Hui "Huan Jing Ke Xue" Bian Ji Wei Yuan Hui.]. 32: 3699-703. PMID 22468543  0.56
2011 Xie J, Hu L, Tang J, Wu X, Li N, Yuan Y, Yang H, Zhang J, Luo S, Chen X. Ecological mechanisms underlying the sustainability of the agricultural heritage rice-fish coculture system. Proceedings of the National Academy of Sciences of the United States of America. 108: E1381-7. PMID 22084110 DOI: 10.1073/pnas.1111043108  0.96
2011 Shi Y, Hu Z, Wu C, Dai J, Li H, Dong J, Wang M, Miao X, Zhou Y, Lu F, Zhang H, Hu L, Jiang Y, Li Z, Chu M, et al. A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1. Nature Genetics. 43: 1215-8. PMID 22037551 DOI: 10.1038/ng.978  1
2011 Chen Y, Inoyama D, Kong AN, Beamer LJ, Hu L. Kinetic analyses of Keap1-Nrf2 interaction and determination of the minimal Nrf2 peptide sequence required for Keap1 binding using surface plasmon resonance. Chemical Biology & Drug Design. 78: 1014-21. PMID 21920027 DOI: 10.1111/j.1747-0285.2011.01240.x  0.56
2011 Wu X, Chen Y, Aloysius H, Hu L. A novel high-yield synthesis of aminoacyl p-nitroanilines and aminoacyl 7-amino-4-methylcoumarins: Important synthons for the synthesis of chromogenic/fluorogenic protease substrates. Beilstein Journal of Organic Chemistry. 7: 1030-5. PMID 21915204 DOI: 10.3762/bjoc.7.117  0.96
2011 Qiu LX, Wang Y, Xia ZG, Xi B, Mao C, Wang JL, Wang BY, Lv FF, Wu XH, Hu LQ. miR-196a2 C allele is a low-penetrant risk factor for cancer development. Cytokine. 56: 589-92. PMID 21907588 DOI: 10.1016/j.cyto.2011.08.019  0.6
2011 Hu L, Meegoda JN, Du J, Gao S, Wu X. Centrifugal study of zone of influence during air-sparging. Journal of Environmental Monitoring : Jem. 13: 2443-9. PMID 21755071 DOI: 10.1039/c0em00594k  0.36
2011 Hu Z, Wu C, Shi Y, Guo H, Zhao X, Yin Z, Yang L, Dai J, Hu L, Tan W, Li Z, Deng Q, Wang J, Wu W, Jin G, et al. A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese. Nature Genetics. 43: 792-6. PMID 21725308 DOI: 10.1038/ng.875  1
2011 Tao Y, Hu L, Li S, Liu Q, Wu X, Li D, Fu P, Wei D, Luo Z. Tranilast prevents the progression of chronic cyclosporine nephrotoxicity through regulation of transforming growth factor β/Smad pathways. Transplantation Proceedings. 43: 1985-8. PMID 21693312 DOI: 10.1016/j.transproceed.2011.01.160  0.96
2011 Han Y, Zhu L, Sun A, Lu X, Hu L, Zhou L, Ren Y, Hu X, Wu X, Wang Z, Ruan C, Wu D. Alterations of hemostatic parameters in the early development of allogeneic hematopoietic stem cell transplantation-related complications. Annals of Hematology. 90: 1201-8. PMID 21674145 DOI: 10.1007/s00277-011-1273-5  0.96
2011 Hu L, Wu X, Han J, Chen L, Vass SO, Browne P, Hall BS, Bot C, Gobalakrishnapillai V, Searle PF, Knox RJ, Wilkinson SR. Synthesis and structure-activity relationships of nitrobenzyl phosphoramide mustards as nitroreductase-activated prodrugs. Bioorganic & Medicinal Chemistry Letters. 21: 3986-91. PMID 21620697 DOI: 10.1016/j.bmcl.2011.05.009  0.64
2011 Hu L, Lu Z, Wang B, Cao J, Ma X, Tian Z, Gao Z, Qin L, Wu X, Liu Y, Wang L. Closure of skin incisions by laser-welding with a combination of two near-infrared diode lasers: preliminary study for determination of optimal parameters. Journal of Biomedical Optics. 16: 038001. PMID 21456880 DOI: 10.1117/1.3552648  0.96
2010 Dai Q, Hu L, Jiang Y, Shi H, Liu J, Zhou W, Shen C, Yang H. An epidemiological survey of bacterial vaginosis, vulvovaginal candidiasis and trichomoniasis in the Tibetan area of Sichuan Province, China. European Journal of Obstetrics, Gynecology, and Reproductive Biology. 150: 207-9. PMID 20207066 DOI: 10.1016/j.ejogrb.2010.02.027  1
2010 Hall BS, Wu X, Hu L, Wilkinson SR. Exploiting the drug-activating properties of a novel trypanosomal nitroreductase. Antimicrobial Agents and Chemotherapy. 54: 1193-9. PMID 20028822 DOI: 10.1128/AAC.01213-09  0.64
2010 Jaberipour M, Vass SO, Guise CP, Grove JI, Knox RJ, Hu L, Hyde EI, Searle PF. Testing double mutants of the enzyme nitroreductase for enhanced cell sensitisation to prodrugs: effects of combining beneficial single mutations. Biochemical Pharmacology. 79: 102-11. PMID 19665450 DOI: 10.1016/j.bcp.2009.07.025  0.4
2009 Jiang Y, Dipaola RS, Hu L. Synthesis and stereochemical preference of peptide 4-aminocyclophosphamide conjugates as potential prodrugs of phosphoramide mustard for activation by prostate-specific antigen (PSA). Bioorganic & Medicinal Chemistry Letters. 19: 2587-90. PMID 19345094 DOI: 10.1016/j.bmcl.2009.03.009  1
2009 Ge Y, Wu X, Zhang D, Hu L. 3-Aminoxypropionate-based linker system for cyclization activation in prodrug design. Bioorganic & Medicinal Chemistry Letters. 19: 941-4. PMID 19097896 DOI: 10.1016/j.bmcl.2008.11.097  0.96
2009 Chen Y, Hu L. Design of anticancer prodrugs for reductive activation. Medicinal Research Reviews. 29: 29-64. PMID 18688784 DOI: 10.1002/med.20137  0.56
2008 Jiang Y, Hu L. N-(2,2-Dimethyl-2-(2-nitrophenyl)acetyl)-4-aminocyclophosphamide as a potential bioreductively activated prodrug of phosphoramide mustard. Bioorganic & Medicinal Chemistry Letters. 18: 4059-63. PMID 18556201 DOI: 10.1016/j.bmcl.2008.05.099  1
2007 Wu X, Hu L. Efficient amidation from carboxylic acids and azides via selenocarboxylates: application to the coupling of amino acids and peptides with azides. The Journal of Organic Chemistry. 72: 765-74. PMID 17253793 DOI: 10.1021/jo061703n  0.96
2007 Jiang Y, Hu L. Phenylalanyl-aminocyclophosphamides as model prodrugs for proteolytic activation: synthesis, stability, and stereochemical requirements for enzymatic cleavage. Bioorganic & Medicinal Chemistry Letters. 17: 517-21. PMID 17064897 DOI: 10.1016/j.bmcl.2006.10.017  1
2006 Jiang Y, Han J, Yu C, Vass SO, Searle PF, Browne P, Knox RJ, Hu L. Design, synthesis, and biological evaluation of cyclic and acyclic nitrobenzylphosphoramide mustards for E. coli nitroreductase activation. Journal of Medicinal Chemistry. 49: 4333-43. PMID 16821793 DOI: 10.1021/jm051246n  1
2005 Hu L. Prodrug Approaches to Drug Delivery Drug Delivery: Principles and Applications. 125-165. DOI: 10.1002/0471475734.ch8  0.64
2004 Searle PF, Chen MJ, Hu L, Race PR, Lovering AL, Grove JI, Guise C, Jaberipour M, James ND, Mautner V, Young LS, Kerr DJ, Mountain A, White SA, Hyde EI. Nitroreductase: a prodrug-activating enzyme for cancer gene therapy. Clinical and Experimental Pharmacology & Physiology. 31: 811-6. PMID 15566399 DOI: 10.1111/j.1440-1681.2004.04085.x  0.4
2004 Hu L. Prodrugs: effective solutions for solubility, permeability and targeting challenges. Idrugs : the Investigational Drugs Journal. 7: 736-42. PMID 15334306  0.64
2004 Hu L. The prodrug approach to better targeting Current Drug Discovery. 28-32.  0.64
2003 Hu L, Yu C, Jiang Y, Han J, Li Z, Browne P, Race PR, Knox RJ, Searle PF, Hyde EI. Nitroaryl phosphoramides as novel prodrugs for E. coli nitroreductase activation in enzyme prodrug therapy. Journal of Medicinal Chemistry. 46: 4818-21. PMID 14584930 DOI: 10.1021/jm034133h  1
2003 Li Z, Han J, Jiang Y, Browne P, Knox RJ, Hu L. Nitrobenzocyclophosphamides as potential prodrugs for bioreductive activation: synthesis, stability, enzymatic reduction, and antiproliferative activity in cell culture. Bioorganic & Medicinal Chemistry. 11: 4171-8. PMID 12951148  1
2002 Yu C, Hu L. Successful Baylis-Hillman reaction of acrylamide with aromatic aldehydes. The Journal of Organic Chemistry. 67: 219-23. PMID 11777462  0.4
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