Alexander Ploss, Ph.D. - Publications

Affiliations: 
2005 Weill Cornell Medical College, New York, NY, United States 
Area:
Immunology, Microbiology Biology

135 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Berggren KA, Sinha S, Lin AE, Schwoerer MP, Maya S, Biswas A, Cafiero TR, Liu Y, Gertje HP, Suzuki S, Berneshawi AR, Carver S, Heller B, Hassan N, Ali Q, ... ... Ploss A, et al. Liver-specific Mettl14 deletion induces nuclear heterotypia and dysregulates RNA export machinery. Biorxiv : the Preprint Server For Biology. PMID 38948765 DOI: 10.1101/2024.06.17.599413  0.743
2024 Wißing MH, Meister TL, Nocke MK, Gömer A, Masovic M, Knegendorf L, Brüggemann Y, Bader V, Siddharta A, Bock CT, Ploss A, Kenney SP, Winklhofer KF, Behrendt P, Wedemeyer H, et al. Genetic determinants of host- and virus-derived insertions for hepatitis E virus replication. Nature Communications. 15: 4855. PMID 38844458 DOI: 10.1038/s41467-024-49219-8  0.34
2024 Allweiss L, Cohen C, Dias J, Fumagalli V, Guo H, Harris JM, Hu J, Iannacone M, Isogawa M, Jeng WJ, Kim KH, Kramvis A, Li W, Lucifora J, Muramatsu M, ... ... Ploss A, et al. Highlights from the 2023 International Meeting on the Molecular Biology of Hepatitis B virus. The Journal of General Virology. 105. PMID 38757942 DOI: 10.1099/jgv.0.001978  0.329
2024 Liu Y, Maya S, Carver S, O'Connell AK, Zen A, Gertje HP, Seneca K, Nahass RG, Crossland NA, Ploss A. Development of a dual channel detection system for pan-genotypic simultaneous quantification of hepatitis B and delta viruses. Emerging Microbes & Infections. 2350167. PMID 38687692 DOI: 10.1080/22221751.2024.2350167  0.362
2024 Ciupe SM, Dahari H, Ploss A. Mathematical Models of Early Hepatitis B Virus Dynamics in Humanized Mice. Bulletin of Mathematical Biology. 86: 53. PMID 38594319 DOI: 10.1007/s11538-024-01284-2  0.311
2023 Kang B, Zhang J, Schwoerer MP, Nelson AN, Schoeman E, Ploss A, Myhrvold C. Highly multiplexed mRNA quantitation with CRISPR-Cas13. Biorxiv : the Preprint Server For Biology. PMID 37645785 DOI: 10.1101/2023.08.16.553527  0.742
2023 Maya S, Hershkovich L, Cardozo-Ojeda EF, Shirvani-Dastgerdi E, Srinivas J, Shekhtman L, Uprichard SL, Berneshawi AR, Cafiero TR, Dahari H, Ploss A. Hepatitis delta virus RNA decline post-inoculation in human NTCP transgenic mice is biphasic. Mbio. e0100823. PMID 37436080 DOI: 10.1128/mbio.01008-23  0.35
2023 Hogan G, Winer BY, Ahodantin J, Sellau J, Huang T, Douam F, Funaki M, Chiriboga L, Su L, Ploss A. Persistent hepatitis B virus and HIV coinfections in dually humanized mice engrafted with human liver and immune system. Journal of Medical Virology. 95: e28930. PMID 37403703 DOI: 10.1002/jmv.28930  0.357
2023 Liu Y, Cafiero TR, Park D, Biswas A, Winer BY, Cho CH, Bram Y, Chandar V, Connell AKO, Gertje HP, Crossland N, Schwartz RE, Ploss A. Targeted viral adaptation generates a simian-tropic hepatitis B virus that infects marmoset cells. Nature Communications. 14: 3582. PMID 37328459 DOI: 10.1038/s41467-023-39148-3  0.35
2023 Maya S, Hershkovich L, Cardozo-Ojeda EF, Shirvani-Dastgerdi E, Srinivas J, Shekhtman L, Uprichard SL, Berneshawi AR, Cafiero TR, Dahari H, Ploss A. Hepatitis delta virus RNA decline post inoculation in human NTCP transgenic mice is biphasic. Biorxiv : the Preprint Server For Biology. PMID 36824865 DOI: 10.1101/2023.02.17.528964  0.368
2022 Schwoerer MP, Ploss A. Barriers to hepatitis C virus infection in mice. Current Opinion in Virology. 56: 101273. PMID 36244239 DOI: 10.1016/j.coviro.2022.101273  0.815
2022 Liu Y, Park D, Cafiero TR, Bram Y, Chandar V, Tseng A, Gertje HP, Crossland NA, Su L, Schwartz RE, Ploss A. Molecular clones of genetically distinct hepatitis B virus genotypes reveal distinct host and drug treatment responses. Jhep Reports : Innovation in Hepatology. 4: 100535. PMID 36035359 DOI: 10.1016/j.jhepr.2022.100535  0.328
2022 Biswas S, Rust LN, Wettengel JM, Yusova S, Fischer M, Carson JN, Johnson J, Wei L, Thode T, Kaadige MR, Sharma S, Agbaria M, Bimber BN, Tu T, Protzer U, ... Ploss A, et al. Long-term hepatitis B virus infection of rhesus macaques requires suppression of host immunity. Nature Communications. 13: 2995. PMID 35637225 DOI: 10.1038/s41467-022-30593-0  0.333
2022 Buksh BF, Knutson SD, Oakley JV, Bissonnette NB, Oblinsky DG, Schwoerer MP, Seath CP, Geri JB, Rodriguez-Rivera FP, Parker DL, Scholes GD, Ploss A, MacMillan DWC. μMap-Red: Proximity Labeling by Red Light Photocatalysis. Journal of the American Chemical Society. 144: 6154-6162. PMID 35363468 DOI: 10.1021/jacs.2c01384  0.731
2021 Zakh R, Churkin A, Bietsch W, Lachiany M, Cotler SJ, Ploss A, Dahari H, Barash D. A Mathematical Model for early HBV and -HDV Kinetics during Anti-HDV Treatment. Mathematics (Basel, Switzerland). 9. PMID 35282153 DOI: 10.3390/math9243323  0.319
2021 Tamura T, Zhang J, Madan V, Biswas A, Schwoerer MP, Cafiero TR, Heller BL, Wang W, Ploss A. Generation and characterization of genetically and antigenically diverse infectious clones of dengue virus serotypes 1-4. Emerging Microbes & Infections. 1-43. PMID 34931940 DOI: 10.1080/22221751.2021.2021808  0.774
2021 Wei L, Ploss A. Mechanism of Hepatitis B Virus cccDNA Formation. Viruses. 13. PMID 34452329 DOI: 10.3390/v13081463  0.319
2021 Liu Y, Maya S, Ploss A. Animal Models of Hepatitis B Virus Infection-Success, Challenges, and Future Directions. Viruses. 13. PMID 33924793 DOI: 10.3390/v13050777  0.341
2020 Brown RJP, Tegtmeyer B, Sheldon J, Khera T, Anggakusuma, Todt D, Vieyres G, Weller R, Joecks S, Zhang Y, Sake S, Bankwitz D, Welsch K, Ginkel C, Engelmann M, ... ... Ploss A, et al. Liver-expressed and limit hepatitis C virus cross-species transmission to mice. Science Advances. 6. PMID 33148654 DOI: 10.1126/sciadv.abd3233  0.607
2020 Berggren KA, Suzuki S, Ploss A. Animal Models Used in Hepatitis C Virus Research. International Journal of Molecular Sciences. 21. PMID 32485887 DOI: 10.3390/Ijms21113869  0.561
2020 Berggren KA, Suzuki S, Ploss A. Animal Models Used in Hepatitis C Virus Research. International Journal of Molecular Sciences. 21. PMID 32485887 DOI: 10.3390/ijms21113869  0.477
2020 Ramanathan HN, Zhang S, Douam F, Mar KB, Chang J, Yang PL, Schoggins JW, Ploss A, Lindenbach BD. A Sensitive Yellow Fever Virus Entry Reporter Identifies Valosin-Containing Protein (VCP/p97) as an Essential Host Factor for Flavivirus Uncoating. Mbio. 11. PMID 32291299 DOI: 10.1128/Mbio.00467-20  0.657
2020 Wei L, Ploss A. Core components of DNA lagging strand synthesis machinery are essential for hepatitis B virus cccDNA formation. Nature Microbiology. PMID 32152586 DOI: 10.1038/S41564-020-0678-0  0.377
2020 Chen CY, Winer BY, Chavez D, Guerra B, Brasky KM, Eng S, Salas E, Tam D, Simmons JH, Abee CR, Delaney WE, Ploss A, Lanford RE, Voitenleitner C. Woolly Monkey-HBV Infection in Squirrel Monkeys as a Surrogate Nonhuman Primate Model of HBV Infection. Hepatology Communications. 4: 371-386. PMID 32140655 DOI: 10.1002/hep4.1471  0.325
2020 Winer B, Edgel KA, Zou X, Sellau J, Hadiwidjojo S, Garver LS, McDonough CE, Kelleher NL, Thomas PM, Villasante E, Ploss A, Gerbasi VR. Identification of Plasmodium falciparum proteoforms from liver stage models. Malaria Journal. 19: 10. PMID 31910830 DOI: 10.1186/S12936-019-3093-3  0.334
2019 Akkina R, Barber DL, Bility MT, Bissig KD, Burwitz BJ, Eichelberg K, Endsley JJ, Garcia JV, Hafner R, Karakousis PC, Korba BE, Koshy R, Lambros C, Menne S, Nuermberger EL, ... Ploss A, et al. Small Animal Models for Human Immunodeficiency Virus (HIV), Hepatitis B, and Tuberculosis: Proceedings of an NIAID Workshop. Current Hiv Research. PMID 31870268 DOI: 10.2174/1570162X18666191223114019  0.379
2019 Ploss A, Kapoor A. Animal Models of Hepatitis C Virus Infection. Cold Spring Harbor Perspectives in Medicine. PMID 31843875 DOI: 10.1101/Cshperspect.A036970  0.548
2019 Maya S, Ploss A. Master of disguise: hepatitis delta virus packaging and spread facilitated by diverse viral envelope proteins. Hepatology (Baltimore, Md.). PMID 31465549 DOI: 10.1002/Hep.30922  0.495
2019 LeDesma R, Nimgaonkar I, Ploss A. Hepatitis E Virus Replication. Viruses. 11. PMID 31390784 DOI: 10.3390/V11080719  0.424
2019 Winer BY, Gaska JM, Lipkowitz G, Bram Y, Parekh A, Parsons L, Leach R, Jindal R, Cho CH, Shrirao A, Novik E, Schwartz RE, Ploss A. Analysis of host responses to hepatitis B and delta viral infections in a micro-scalable hepatic co-culture system. Hepatology (Baltimore, Md.). PMID 31206195 DOI: 10.1002/Hep.30815  0.484
2019 Gaska JM, Balev M, Ding Q, Heller B, Ploss A. Differences across cyclophilin A orthologs contribute to the host range restriction of hepatitis C virus. Elife. 8. PMID 31074414 DOI: 10.7554/Elife.44436  0.546
2019 Mesev EV, LeDesma RA, Ploss A. Decoding type I and III interferon signalling during viral infection. Nature Microbiology. PMID 30936491 DOI: 10.1038/S41564-019-0421-X  0.381
2019 Gaska JM, Ding Q, Ploss A. Mouse Models for Studying HCV Vaccines and Therapeutic Antibodies. Methods in Molecular Biology (Clifton, N.J.). 1911: 481-503. PMID 30593647 DOI: 10.1007/978-1-4939-8976-8_33  0.511
2019 Gaska JM, Balev M, Ding Q, Heller B, Ploss A. Author response: Differences across cyclophilin A orthologs contribute to the host range restriction of hepatitis C virus Elife. DOI: 10.7554/Elife.44436.022  0.442
2018 Douam F, Ziegler CGK, Hrebikova G, Fant B, Leach R, Parsons L, Wang W, Gaska JM, Winer BY, Heller B, Shalek AK, Ploss A. Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses. Nature Communications. 9: 5031. PMID 30487575 DOI: 10.1038/S41467-018-07478-2  0.365
2018 Winer BY, Shirvani-Dastgerdi E, Bram Y, Sellau J, Low BE, Johnson H, Huang T, Hrebikova G, Heller B, Sharon Y, Giersch K, Gerges S, Seneca K, Pais MA, Frankel AS, ... ... Ploss A, et al. Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection. Science Translational Medicine. 10. PMID 29950446 DOI: 10.1126/Scitranslmed.Aap9328  0.504
2018 Douam F, Ploss A. Yellow Fever Virus: Knowledge Gaps Impeding the Fight Against an Old Foe. Trends in Microbiology. PMID 29933925 DOI: 10.1016/J.Tim.2018.05.012  0.339
2018 Ding Q, Gaska JM, Douam F, Wei L, Kim D, Balev M, Heller B, Ploss A. Species-specific disruption of STING-dependent antiviral cellular defenses by the Zika virus NS2B3 protease. Proceedings of the National Academy of Sciences of the United States of America. PMID 29915078 DOI: 10.1073/Pnas.1803406115  0.486
2018 Ding Q, Nimgaonkar I, Archer NF, Bram Y, Heller B, Schwartz RE, Ploss A. Identification of the Intragenomic Promoter Controlling Hepatitis E Virus Subgenomic RNA Transcription. Mbio. 9. PMID 29739903 DOI: 10.1128/Mbio.00769-18  0.394
2018 Dragovic SM, Agunbiade TA, Freudzon M, Yang J, Hastings AK, Schleicher TR, Zhou X, Craft S, Chuang YM, Gonzalez F, Li Y, Hrebikova G, Tripathi A, Mlambo G, Almeras L, ... Ploss A, et al. Immunization with AgTRIO, a Protein in Anopheles Saliva, Contributes to Protection against Plasmodium Infection in Mice. Cell Host & Microbe. 23: 523-535.e5. PMID 29649443 DOI: 10.1016/J.Chom.2018.03.008  0.366
2018 Douam F, Ploss A. The use of humanized mice for studies of viral pathogenesis and immunity. Current Opinion in Virology. 29: 62-71. PMID 29604551 DOI: 10.1016/J.Coviro.2018.03.003  0.393
2018 Douam F, Fusil F, Enguehard M, Dib L, Nadalin F, Schwaller L, Hrebikova G, Mancip J, Mailly L, Montserret R, Ding Q, Maisse C, Carlot E, Xu K, Verhoeyen E, ... ... Ploss A, et al. A protein coevolution method uncovers critical features of the Hepatitis C Virus fusion mechanism. Plos Pathogens. 14: e1006908. PMID 29505618 DOI: 10.1371/Journal.Ppat.1006908  0.515
2018 Winer BY, Parekh A, Heller B, Lipkowitz G, Guo R, Cho C, Shrirao A, Pludwinski E, Novik E, Ploss A. Persistent Hepatitis B virus infection in self-assembling microscale primary hepatocyte co-culture Drug Metabolism and Pharmacokinetics. 33: S59-S60. DOI: 10.1016/J.Dmpk.2017.11.201  0.394
2017 Nimgaonkar I, Ding Q, Schwartz RE, Ploss A. Hepatitis E virus: advances and challenges. Nature Reviews. Gastroenterology & Hepatology. PMID 29162935 DOI: 10.1038/Nrgastro.2017.150  0.435
2017 Nimgaonkar I, Ploss A. A porcine model for chronic hepatitis E. Hepatology (Baltimore, Md.). PMID 28961321 DOI: 10.1002/Hep.29566  0.338
2017 Douam F, Soto Albrecht YE, Hrebikova G, Sadimin E, Davidson C, Kotenko SV, Ploss A. Type III Interferon-Mediated Signaling Is Critical for Controlling Live Attenuated Yellow Fever Virus Infection In Vivo. Mbio. 8. PMID 28811340 DOI: 10.1128/Mbio.00819-17  0.397
2017 Winer BY, Huang TS, Pludwinski E, Heller B, Wojcik F, Lipkowitz GE, Parekh A, Cho C, Shrirao A, Muir TW, Novik E, Ploss A. Long-term hepatitis B infection in a scalable hepatic co-culture system. Nature Communications. 8: 125. PMID 28743900 DOI: 10.1038/S41467-017-00200-8  0.466
2017 Li D, Wang X, von Schaewen M, Tao W, Zhang Y, Heller B, Hrebikova G, Deng Q, Sun Q, Ploss A, Zhong J, Huang Z. Immunization with a subunit hepatitis C virus vaccine elicits pan-genotypic neutralizing antibodies and intra-hepatic T-cell responses in non-human primates. The Journal of Infectious Diseases. PMID 28398489 DOI: 10.1093/Infdis/Jix180  0.514
2017 Shirvani-Dastgerdi E, Winer BY, Celia-Terrassa A, Kang Y, Tabernero D, Yagmur E, Rodríguez-Frías F, Gregori J, Luedde T, Trautwein C, Ploss A, Tacke F. Selection of the highly replicative and partially multidrug resistant rtS78T polymerase mutation in two patients with chronic hepatitis B virus infection during tenofovir-entecavir combination therapy. Journal of Hepatology. PMID 28392234 DOI: 10.1016/J.Jhep.2017.03.027  0.382
2017 Douam F, Hrebikova G, Albrecht YE, Sellau J, Sharon Y, Ding Q, Ploss A. Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome. Nature Communications. 8: 14781. PMID 28290449 DOI: 10.1038/Ncomms14781  0.42
2017 Ding Q, Heller B, Capuccino JM, Song B, Nimgaonkar I, Hrebikova G, Contreras JE, Ploss A. Hepatitis E virus ORF3 is a functional ion channel required for release of infectious particles. Proceedings of the National Academy of Sciences of the United States of America. PMID 28096411 DOI: 10.1073/Pnas.1614955114  0.375
2016 Winer BY, Huang T, Low BE, Avery C, Pais MA, Hrebikova G, Siu E, Chiriboga L, Wiles MV, Ploss A. Recapitulation of treatment response patterns in a novel humanized mouse model for chronic hepatitis B virus infection. Virology. 502: 63-72. PMID 28006671 DOI: 10.1016/J.Virol.2016.12.017  0.453
2016 Ding Q, von Schaewen M, Hrebikova G, Heller B, Sandmann L, Plaas M, Ploss A. Mice expressing minimally humanized CD81 and occludin genes support hepatitis C virus uptake in vivo. Journal of Virology. PMID 27928007 DOI: 10.1128/Jvi.01799-16  0.544
2016 von Schaewen M, Dorner M, Hueging K, Foquet L, Gerges S, Hrebikova G, Heller B, Bitzegeio J, Doerrbecker J, Horwitz JA, Gerold G, Suerbaum S, Rice CM, Meuleman P, Pietschmann T, ... Ploss A, et al. Expanding the Host Range of Hepatitis C Virus through Viral Adaptation. Mbio. 7. PMID 27834208 DOI: 10.1128/Mbio.01915-16  0.666
2016 Li D, von Schaewen M, Wang X, Tao W, Zhang Y, Li L, Heller B, Hrebikova G, Deng Q, Ploss A, Zhong J, Huang Z. Altered glycosylation patterns increase immunogenicity of a subunit HCV vaccine inducing neutralizing antibodies which confer protection in mice. Journal of Virology. PMID 27630242 DOI: 10.1128/Jvi.01462-16  0.492
2016 Shirvani-Dastgerdi E, Schwartz RE, Ploss A. Hepatocarcinogenesis associated with hepatitis B, delta and C viruses. Current Opinion in Virology. 20: 1-10. PMID 27504999 DOI: 10.1016/J.Coviro.2016.07.009  0.442
2016 Bartucci M, Ferrari AC, Kim IY, Ploss A, Yarmush M, Sabaawy HE. Personalized Medicine Approaches in Prostate Cancer Employing Patient Derived 3D Organoids and Humanized Mice. Frontiers in Cell and Developmental Biology. 4: 64. PMID 27446916 DOI: 10.3389/Fcell.2016.00064  0.309
2016 von Schaewen M, Hrebikova G, Ploss A. Generation of Human Liver Chimeric Mice for the Study of Human Hepatotropic Pathogens. Methods in Molecular Biology (Clifton, N.J.). 1438: 79-101. PMID 27150085 DOI: 10.1007/978-1-4939-3661-8_5  0.344
2016 Winer BY, Ding Q, Gaska J, Ploss A. In vivo models of hepatitis B and C virus infection. Febs Letters. PMID 27009462 DOI: 10.1002/1873-3468.12157  0.545
2016 Douam F, Ding Q, Ploss A. Recent advances in understanding hepatitis C. F1000research. 5. PMID 26918166 DOI: 10.12688/F1000Research.7354.1  0.535
2016 Winer BY, Ploss A. Breaking the species barrier for hepatitis delta virus. Hepatology (Baltimore, Md.). 63: 334-6. PMID 26289017 DOI: 10.1002/Hep.28129  0.406
2015 von Schaewen M, Ploss A. Novel Biomarkers Associated With the Outcome of Interferon-Based Hepatitis C Virus Therapy. Cellular and Molecular Gastroenterology and Hepatology. 1: 257-258. PMID 28210676 DOI: 10.1016/J.Jcmgh.2015.03.005  0.394
2015 Douam F, Gaska JM, Winer BY, Ding Q, von Schaewen M, Ploss A. Genetic Dissection of the Host Tropism of Human-Tropic Pathogens. Annual Review of Genetics. PMID 26407032 DOI: 10.1146/Annurev-Genet-112414-054823  0.337
2015 Perin PM, Haid S, Brown RJ, Doerrbecker J, Schulze K, Zeilinger C, von Schaewen M, Heller B, Vercauteren K, Luxenburger E, Baktash YM, Vondran FW, Speerstra S, Awadh A, Mukhtarov F, ... ... Ploss A, et al. Flunarizine prevents hepatitis C virus membrane fusion in a genotype-dependent manner by targeting the potential fusion peptide within E1. Hepatology (Baltimore, Md.). PMID 26248546 DOI: 10.1002/Hep.28111  0.473
2015 Ploss A, Walker C. Editorial overview: Progress and challenges in modeling human viral diseases in vivo. Current Opinion in Virology. 13: v-vii. PMID 26219570 DOI: 10.1016/J.Coviro.2015.07.004  0.359
2015 Winer BY, Ploss A. Determinants of hepatitis B and delta virus host tropism. Current Opinion in Virology. 13: 109-16. PMID 26164658 DOI: 10.1016/J.Coviro.2015.06.004  0.485
2015 Scull MA, Shi C, de Jong YP, Gerold G, Ries M, von Schaewen M, Donovan BM, Labitt RN, Horwitz JA, Gaska JM, Hrebikova G, Xiao JW, Flatley B, Fung C, Chiriboga L, ... ... Ploss A, et al. Hepatitis C virus infects rhesus macaque hepatocytes and simianized mice. Hepatology (Baltimore, Md.). 62: 57-67. PMID 25820364 DOI: 10.1002/Hep.27773  0.636
2015 Douam F, Ploss A. Proteomic approaches to analyzing hepatitis C virus biology. Proteomics. 15: 2051-65. PMID 25809442 DOI: 10.1002/Pmic.201500009  0.534
2015 Stoddard MB, Li H, Wang S, Saeed M, Andrus L, Ding W, Jiang X, Learn GH, von Schaewen M, Wen J, Goepfert PA, Hahn BH, Ploss A, Rice CM, Shaw GM. Identification, molecular cloning, and analysis of full-length hepatitis C virus transmitted/founder genotypes 1, 3, and 4. Mbio. 6: e02518. PMID 25714714 DOI: 10.1128/Mbio.02518-14  0.595
2015 Siu E, Ploss A. Modeling malaria in humanized mice: opportunities and challenges. Annals of the New York Academy of Sciences. 1342: 29-36. PMID 25678404 DOI: 10.1111/Nyas.12618  0.33
2015 Gaska JM, Ploss A. Study of viral pathogenesis in humanized mice. Current Opinion in Virology. 11: 14-20. PMID 25618248 DOI: 10.1016/J.Coviro.2015.01.002  0.425
2015 Perin P, Haid S, Brown R, Schulze K, Colpitts C, Zeilinger C, von Schaewen M, Heller B, Vercauteren K, Luxenburger E, Andonyadis Y, Vondran F, Kirschning A, Schang L, Müller R, ... ... Ploss A, et al. P0674 : Clinically approved T-type calcium channel inhibitors prevent hepatitis C virus (HCV) membrane fusion in a genotype-dependent manner Journal of Hepatology. 62: S574-S575. DOI: 10.1016/S0168-8278(15)30878-3  0.429
2014 Ding Q, von Schaewen M, Ploss A. The impact of hepatitis C virus entry on viral tropism. Cell Host & Microbe. 16: 562-8. PMID 25525789 DOI: 10.1016/J.Chom.2014.10.009  0.524
2014 de Jong YP, Dorner M, Mommersteeg MC, Xiao JW, Balazs AB, Robbins JB, Winer BY, Gerges S, Vega K, Labitt RN, Donovan BM, Giang E, Krishnan A, Chiriboga L, Charlton MR, ... ... Ploss A, et al. Broadly neutralizing antibodies abrogate established hepatitis C virus infection. Science Translational Medicine. 6: 254ra129. PMID 25232181 DOI: 10.1126/Scitranslmed.3009512  0.652
2014 Ploss A. Mouse models for human infectious diseases. Journal of Immunological Methods. 410: 1-2. PMID 25017506 DOI: 10.1016/J.Jim.2014.07.002  0.308
2014 Billerbeck E, Labitt RN, Vega K, Frias-Staheli N, Dorner M, Xiao JW, Rice CM, Ploss A. Insufficient interleukin-12 signalling favours differentiation of human CD4(+) and CD8(+) T cells into GATA-3(+) and GATA-3(+) T-bet(+) subsets in humanized mice. Immunology. 143: 202-18. PMID 24766459 DOI: 10.1111/Imm.12304  0.488
2014 von Schaewen M, Ding Q, Ploss A. Visualizing hepatitis C virus infection in humanized mice. Journal of Immunological Methods. 410: 50-9. PMID 24642425 DOI: 10.1016/J.Jim.2014.03.006  0.55
2014 Sheahan T, Imanaka N, Marukian S, Dorner M, Liu P, Ploss A, Rice CM. Interferon lambda alleles predict innate antiviral immune responses and hepatitis C virus permissiveness. Cell Host & Microbe. 15: 190-202. PMID 24528865 DOI: 10.1016/J.Chom.2014.01.007  0.651
2014 von Schaewen M, Ploss A. Murine models of hepatitis C: what can we look forward to? Antiviral Research. 104: 15-22. PMID 24462693 DOI: 10.1016/J.Antiviral.2014.01.007  0.575
2014 Frias-Staheli N, Dorner M, Marukian S, Billerbeck E, Labitt RN, Rice CM, Ploss A. Utility of humanized BLT mice for analysis of dengue virus infection and antiviral drug testing. Journal of Virology. 88: 2205-18. PMID 24335303 DOI: 10.1128/Jvi.03085-13  0.606
2014 Anggakusuma, Colpitts CC, Schang LM, Rachmawati H, Frentzen A, Pfaender S, Behrendt P, Brown RJ, Bankwitz D, Steinmann J, Ott M, Meuleman P, Rice CM, Ploss A, Pietschmann T, et al. Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells. Gut. 63: 1137-49. PMID 23903236 DOI: 10.1136/Gutjnl-2012-304299  0.637
2014 Behrendt P, Steinmann E, Kusuma A, Perin P, Menzel N, Ploss A, Meulemann P, Manns M, Pietschmann T. P233 THE NATURAL COMPOUND PENTA-O-GALLOYL-GLUCOSE, DERIVED FROM THE ROOT CORTEX MOUTAN, EFFICIENTLY INHIBITS HEPATITIS C-VIRUS ENTRY AND SHOWS EXCELLENT PHARMACOKINETIC PERFORMANCE IN VIVO Journal of Hepatology. 60: S143. DOI: 10.1016/S0168-8278(14)60395-0  0.337
2013 Horwitz JA, Halper-Stromberg A, Mouquet H, Gitlin AD, Tretiakova A, Eisenreich TR, Malbec M, Gravemann S, Billerbeck E, Dorner M, Büning H, Schwartz O, Knops E, Kaiser R, Seaman MS, ... ... Ploss A, et al. HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice. Proceedings of the National Academy of Sciences of the United States of America. 110: 16538-43. PMID 24043801 DOI: 10.1073/Pnas.1315295110  0.489
2013 Dorner M, Horwitz JA, Donovan BM, Labitt RN, Budell WC, Friling T, Vogt A, Catanese MT, Satoh T, Kawai T, Akira S, Law M, Rice CM, Ploss A. Completion of the entire hepatitis C virus life cycle in genetically humanized mice. Nature. 501: 237-41. PMID 23903655 DOI: 10.1038/Nature12427  0.665
2013 Billerbeck E, Horwitz JA, Labitt RN, Donovan BM, Vega K, Budell WC, Koo GC, Rice CM, Ploss A. Characterization of human antiviral adaptive immune responses during hepatotropic virus infection in HLA-transgenic human immune system mice. Journal of Immunology (Baltimore, Md. : 1950). 191: 1753-64. PMID 23833235 DOI: 10.4049/Jimmunol.1201518  0.578
2013 Vogt A, Scull MA, Friling T, Horwitz JA, Donovan BM, Dorner M, Gerold G, Labitt RN, Rice CM, Ploss A. Recapitulation of the hepatitis C virus life-cycle in engineered murine cell lines. Virology. 444: 1-11. PMID 23777661 DOI: 10.1016/J.Virol.2013.05.036  0.646
2013 Gruell H, Bournazos S, Ravetch JV, Ploss A, Nussenzweig MC, Pietzsch J. Antibody and antiretroviral preexposure prophylaxis prevent cervicovaginal HIV-1 infection in a transgenic mouse model. Journal of Virology. 87: 8535-44. PMID 23720722 DOI: 10.1128/Jvi.00868-13  0.333
2013 Guermonprez P, Helft J, Claser C, Deroubaix S, Karanje H, Gazumyan A, Darasse-Jèze G, Telerman SB, Breton G, Schreiber HA, Frias-Staheli N, Billerbeck E, Dorner M, Rice CM, Ploss A, et al. Inflammatory Flt3l is essential to mobilize dendritic cells and for T cell responses during Plasmodium infection. Nature Medicine. 19: 730-8. PMID 23685841 DOI: 10.1038/Nm.3197  0.531
2013 Horwitz JA, Dorner M, Friling T, Donovan BM, Vogt A, Loureiro J, Oh T, Rice CM, Ploss A. Expression of heterologous proteins flanked by NS3-4A cleavage sites within the hepatitis C virus polyprotein. Virology. 439: 23-33. PMID 23485372 DOI: 10.1016/J.Virol.2013.01.019  0.621
2013 Billerbeck E, de Jong Y, Dorner M, de la Fuente C, Ploss A. Animal models for hepatitis C. Current Topics in Microbiology and Immunology. 369: 49-86. PMID 23463197 DOI: 10.1007/978-3-642-27340-7_3  0.544
2013 Shi C, Ploss A. Hepatitis C virus vaccines in the era of new direct-acting antivirals. Expert Review of Gastroenterology & Hepatology. 7: 171-85. PMID 23363265 DOI: 10.1586/Egh.12.72  0.492
2013 Sandmann L, Ploss A. Barriers of hepatitis C virus interspecies transmission. Virology. 435: 70-80. PMID 23217617 DOI: 10.1016/J.Virol.2012.09.044  0.542
2013 Dorner M, Rice CM, Ploss A. Study of hepatitis C virus entry in genetically humanized mice. Methods (San Diego, Calif.). 59: 249-57. PMID 22687621 DOI: 10.1016/J.Ymeth.2012.05.010  0.663
2013 de Jong Y, Dorner M, Balazs A, Robbins J, Labitt R, Donovan B, Krishnan A, Charlton M, Chiriboga L, Burton D, Rice C, Baltimore D, Law M, Ploss A. 1146 THE EFFECTS OF BROADLY NEUTRALIZING ANTIBODIES IN EXPERIMENTAL HCV INFECTION Journal of Hepatology. 58: S466-S467. DOI: 10.1016/S0168-8278(13)61147-2  0.594
2013 Schwartz RE, Trehan K, Andrus L, Sheahan T, Ploss A, Duncan SA, Rice CM, Bhatia S. Mo1783 Personalizing the Study of Infectious Disease: Modeling Hepatitis C Virus Using Induced Pluripotent Stem Cells Gastroenterology. 144: S-1025. DOI: 10.1016/S0016-5085(13)63810-X  0.56
2012 Klein F, Halper-Stromberg A, Horwitz JA, Gruell H, Scheid JF, Bournazos S, Mouquet H, Spatz LA, Diskin R, Abadir A, Zang T, Dorner M, Billerbeck E, Labitt RN, Gaebler C, ... ... Ploss A, et al. HIV therapy by a combination of broadly neutralizing antibodies in humanized mice. Nature. 492: 118-22. PMID 23103874 DOI: 10.1038/Nature11604  0.32
2012 Vaughan AM, Mikolajczak SA, Wilson EM, Grompe M, Kaushansky A, Camargo N, Bial J, Ploss A, Kappe SH. Complete Plasmodium falciparum liver-stage development in liver-chimeric mice. The Journal of Clinical Investigation. 122: 3618-28. PMID 22996664 DOI: 10.1172/Jci62684  0.374
2012 Schoggins JW, Dorner M, Feulner M, Imanaka N, Murphy MY, Ploss A, Rice CM. Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro. Proceedings of the National Academy of Sciences of the United States of America. 109: 14610-5. PMID 22908290 DOI: 10.1073/Pnas.1212379109  0.564
2012 Vaughan AM, Kappe SH, Ploss A, Mikolajczak SA. Development of humanized mouse models to study human malaria parasite infection. Future Microbiology. 7: 657-65. PMID 22568719 DOI: 10.2217/Fmb.12.27  0.341
2012 Ploss A, Dubuisson J. New advances in the molecular biology of hepatitis C virus infection: towards the identification of new treatment targets. Gut. 61: i25-35. PMID 22504917 DOI: 10.1136/Gutjnl-2012-302048  0.523
2012 Giang E, Dorner M, Prentoe JC, Dreux M, Evans MJ, Bukh J, Rice CM, Ploss A, Burton DR, Law M. Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus. Proceedings of the National Academy of Sciences of the United States of America. 109: 6205-10. PMID 22492964 DOI: 10.1073/Pnas.1114927109  0.72
2012 Ploss A, Evans MJ. Hepatitis C virus host cell entry. Current Opinion in Virology. 2: 14-9. PMID 22440961 DOI: 10.1016/J.Coviro.2011.12.007  0.678
2012 Meng X, Schoggins J, Rose L, Cao J, Ploss A, Rice CM, Xiang Y. C7L family of poxvirus host range genes inhibits antiviral activities induced by type I interferons and interferon regulatory factor 1. Journal of Virology. 86: 4538-47. PMID 22345458 DOI: 10.1128/Jvi.06140-11  0.548
2012 Schwartz RE, Trehan K, Andrus L, Sheahan TP, Ploss A, Duncan SA, Rice CM, Bhatia SN. Modeling hepatitis C virus infection using human induced pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 2544-8. PMID 22308485 DOI: 10.1073/Pnas.1121400109  0.599
2012 Scull MA, Ploss A. Exiting from uncharted territory: hepatitis C virus assembles in mouse cell lines. Hepatology (Baltimore, Md.). 55: 645-8. PMID 22287293 DOI: 10.1002/Hep.24716  0.529
2012 Vogt A, Horwitz J, Scull M, Dorner M, Gerold G, Rice C, Ploss A. 103 RECAPITULATION OF THE ENTIRE HEPATITIS C VIRUS LIFE IN ENGINEERED MOUSE CELL LINES Journal of Hepatology. 56: S46. DOI: 10.1016/S0168-8278(12)60117-2  0.548
2012 Schwartz R, Trehan K, Andrus L, Sheahan T, Ploss A, Duncan SA, Rice C, Bhatia S. Su1581 Modeling Hepatitis C Virus Infection Using Human Induced Pluripotent Stem Cells Gastroenterology. 142: S-971. DOI: 10.1016/S0016-5085(12)63761-5  0.597
2012 Ploss A. Reverse Genetic Tools to Study Hepatitis C Virus Reverse Genetics of Rna Viruses: Applications and Perspectives. 64-90. DOI: 10.1002/9781118405338.ch3  0.315
2011 Dorner M, Ploss A. Deconstructing hepatitis C virus infection in humanized mice. Annals of the New York Academy of Sciences. 1245: 59-62. PMID 22211981 DOI: 10.1111/J.1749-6632.2011.06317.X  0.483
2011 Andrus L, Marukian S, Jones CT, Catanese MT, Sheahan TP, Schoggins JW, Barry WT, Dustin LB, Trehan K, Ploss A, Bhatia SN, Rice CM. Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells. Hepatology (Baltimore, Md.). 54: 1901-12. PMID 22144107 DOI: 10.1002/Hep.24557  0.648
2011 Marukian S, Andrus L, Sheahan TP, Jones CT, Charles ED, Ploss A, Rice CM, Dustin LB. Hepatitis C virus induces interferon-λ and interferon-stimulated genes in primary liver cultures. Hepatology (Baltimore, Md.). 54: 1913-23. PMID 21800339 DOI: 10.1002/Hep.24580  0.639
2011 Dorner M, Horwitz JA, Robbins JB, Barry WT, Feng Q, Mu K, Jones CT, Schoggins JW, Catanese MT, Burton DR, Law M, Rice CM, Ploss A. A genetically humanized mouse model for hepatitis C virus infection. Nature. 474: 208-11. PMID 21654804 DOI: 10.1038/Nature10168  0.667
2011 Billerbeck E, Barry WT, Mu K, Dorner M, Rice CM, Ploss A. Development of human CD4+FoxP3+ regulatory T cells in human stem cell factor-, granulocyte-macrophage colony-stimulating factor-, and interleukin-3-expressing NOD-SCID IL2Rγ(null) humanized mice. Blood. 117: 3076-86. PMID 21252091 DOI: 10.1182/Blood-2010-08-301507  0.514
2011 Washburn ML, Bility MT, Zhang L, Kovalev GI, Buntzman A, Frelinger JA, Barry W, Ploss A, Rice CM, Su L. A humanized mouse model to study hepatitis C virus infection, immune response, and liver disease. Gastroenterology. 140: 1334-44. PMID 21237170 DOI: 10.1053/J.Gastro.2011.01.001  0.661
2011 de Jong YP, Rice CM, Ploss A. Evaluation of combination therapy against hepatitis C virus infection in human liver chimeric mice. Journal of Hepatology. 54: 848-50. PMID 21145816 DOI: 10.1016/J.Jhep.2010.09.034  0.655
2010 Gerold G, Rice CM, Ploss A. Teaching new tricks to an old foe: murinizing hepatitis C virus. Hepatology (Baltimore, Md.). 52: 2233-6. PMID 21105113 DOI: 10.1002/Hep.24045  0.639
2010 Sheahan T, Jones CT, Ploss A. Advances and challenges in studying hepatitis C virus in its native environment. Expert Review of Gastroenterology & Hepatology. 4: 541-50. PMID 20932139 DOI: 10.1586/Egh.10.53  0.537
2010 Kohaar I, Ploss A, Korol E, Mu K, Schoggins JW, O'Brien TR, Rice CM, Prokunina-Olsson L. Splicing diversity of the human OCLN gene and its biological significance for hepatitis C virus entry. Journal of Virology. 84: 6987-94. PMID 20463075 DOI: 10.1128/Jvi.00196-10  0.647
2010 de Jong YP, Rice CM, Ploss A. New horizons for studying human hepatotropic infections. The Journal of Clinical Investigation. 120: 650-3. PMID 20179350 DOI: 10.1172/Jci42338  0.619
2010 Ploss A, Khetani SR, Jones CT, Syder AJ, Trehan K, Gaysinskaya VA, Mu K, Ritola K, Rice CM, Bhatia SN. Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures. Proceedings of the National Academy of Sciences of the United States of America. 107: 3141-5. PMID 20133632 DOI: 10.1073/Pnas.0915130107  0.643
2010 Jones CT, Catanese MT, Law LM, Khetani SR, Syder AJ, Ploss A, Oh TS, Schoggins JW, MacDonald MR, Bhatia SN, Rice CM. Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system. Nature Biotechnology. 28: 167-71. PMID 20118917 DOI: 10.1038/Nbt.1604  0.643
2009 Akondy RS, Monson ND, Miller JD, Edupuganti S, Teuwen D, Wu H, Quyyumi F, Garg S, Altman JD, Del Rio C, Keyserling HL, Ploss A, Rice CM, Orenstein WA, Mulligan MJ, et al. The yellow fever virus vaccine induces a broad and polyfunctional human memory CD8+ T cell response. Journal of Immunology (Baltimore, Md. : 1950). 183: 7919-30. PMID 19933869 DOI: 10.4049/Jimmunol.0803903  0.508
2009 Ploss A, Rice CM. Towards a small animal model for hepatitis C. Embo Reports. 10: 1220-7. PMID 19834510 DOI: 10.1038/Embor.2009.223  0.637
2009 Legrand N, Ploss A, Balling R, Becker PD, Borsotti C, Brezillon N, Debarry J, de Jong Y, Deng H, Di Santo JP, Eisenbarth S, Eynon E, Flavell RA, Guzman CA, Huntington ND, et al. Humanized mice for modeling human infectious disease: challenges, progress, and outlook. Cell Host & Microbe. 6: 5-9. PMID 19616761 DOI: 10.1016/J.Chom.2009.06.006  0.563
2009 Strowig T, Gurer C, Ploss A, Liu YF, Arrey F, Sashihara J, Koo G, Rice CM, Young JW, Chadburn A, Cohen JI, Münz C. Priming of protective T cell responses against virus-induced tumors in mice with human immune system components. The Journal of Experimental Medicine. 206: 1423-34. PMID 19487422 DOI: 10.1084/Jem.20081720  0.566
2009 Ploss A, Evans MJ, Gaysinskaya VA, Panis M, You H, de Jong YP, Rice CM. Human occludin is a hepatitis C virus entry factor required for infection of mouse cells. Nature. 457: 882-6. PMID 19182773 DOI: 10.1038/Nature07684  0.747
2007 Biswas PS, Pedicord V, Ploss A, Menet E, Leiner I, Pamer EG. Pathogen-specific CD8 T cell responses are directly inhibited by IL-10. Journal of Immunology (Baltimore, Md. : 1950). 179: 4520-8. PMID 17878348 DOI: 10.4049/Jimmunol.179.7.4520  0.515
2006 Lindenbach BD, Meuleman P, Ploss A, Vanwolleghem T, Syder AJ, McKeating JA, Lanford RE, Feinstone SM, Major ME, Leroux-Roels G, Rice CM. Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro. Proceedings of the National Academy of Sciences of the United States of America. 103: 3805-9. PMID 16484368 DOI: 10.1073/Pnas.0511218103  0.771
2005 Ploss A, Leiner I, Pamer EG. Distinct regulation of H2-M3-restricted memory T cell responses in lymph node and spleen. Journal of Immunology (Baltimore, Md. : 1950). 175: 5998-6005. PMID 16237094 DOI: 10.4049/Jimmunol.175.9.5998  0.528
2005 Ploss A, Tran A, Menet E, Leiner I, Pamer EG. Cross-recognition of N-formylmethionine peptides is a general characteristic of H2-M3-restricted CD8+ T cells. Infection and Immunity. 73: 4423-6. PMID 15972542 DOI: 10.1128/Iai.73.7.4423-4426.2005  0.499
2004 Dao T, Guo D, Ploss A, Stolzer A, Saylor C, Boursalian TE, Im JS, Sant'Angelo DB. Development of CD1d-restricted NKT cells in the mouse thymus. European Journal of Immunology. 34: 3542-52. PMID 15549774 DOI: 10.1002/Eji.200425546  0.301
2004 Wong P, Lara-Tejero M, Ploss A, Leiner I, Pamer EG. Rapid development of T cell memory. Journal of Immunology (Baltimore, Md. : 1950). 172: 7239-45. PMID 15187098 DOI: 10.4049/Jimmunol.172.12.7239  0.521
2003 Ploss A, Lauvau G, Contos B, Kerksiek KM, Guirnalda PD, Leiner I, Lenz LL, Bevan MJ, Pamer EG. Promiscuity of MHC class Ib-restricted T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 171: 5948-55. PMID 14634106 DOI: 10.4049/Jimmunol.171.11.5948  0.632
2003 Kerksiek KM, Ploss A, Leiner I, Busch DH, Pamer EG. H2-M3-restricted memory T cells: persistence and activation without expansion. Journal of Immunology (Baltimore, Md. : 1950). 170: 1862-9. PMID 12574352 DOI: 10.4049/Jimmunol.170.4.1862  0.616
2001 Reuss FU, Heber R, Ploss A, Berdel B. Amphotropic murine leukemia virus replication in human mammary epithelial cells and the formation of cytomegalovirus-promoter recombinants Virology. 291: 91-100. PMID 11878879 DOI: 10.1006/Viro.2001.1199  0.411
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