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Jignesh M. Doshi, Ph.D. - Publications

Affiliations: 
2008 Medicinal Chemistry University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Pharmaceutical Chemistry, Organic Chemistry
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6 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Das SG, Srinivasan B, Hermanson DL, Bleeker NP, Doshi JM, Tang R, Beck WT, Xing C. Structure-activity relationship and molecular mechanisms of ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) and its analogues. Journal of Medicinal Chemistry. 54: 5937-48. PMID 21780800 DOI: 10.1021/Jm200764T  0.609
2009 Das SG, Doshi JM, Tian D, Addo SN, Srinivasan B, Hermanson DL, Xing C. Structure-activity relationship and molecular mechanisms of ethyl 2-amino-4-(2-ethoxy-2-oxoethyl)-6-phenyl-4h-chromene-3-carboxylate (sha 14-1) and its analogues. Journal of Medicinal Chemistry. 52: 5937-49. PMID 19743858 DOI: 10.1021/Jm9005059  0.62
2008 Tian D, Das SG, Doshi JM, Peng J, Lin J, Xing C. sHA 14-1, a stable and ROS-free antagonist against anti-apoptotic Bcl-2 proteins, bypasses drug resistances and synergizes cancer therapies in human leukemia cell. Cancer Letters. 259: 198-208. PMID 18037229 DOI: 10.1016/J.Canlet.2007.10.012  0.652
2008 Doshi JM, Xing C. Antagonists against anti-apoptotic Bcl-2 family proteins for cancer treatment Mini-Reviews in Organic Chemistry. 5: 171-178. DOI: 10.2174/157019308785161639  0.63
2007 Doshi JM, Tian D, Xing C. Ethyl-2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H- chromene-3-carboxylate (HA 14-1), a prototype small-molecule antagonist against antiapoptotic Bcl-2 proteins, decomposes to generate reactive oxygen species that induce apoptosis. Molecular Pharmaceutics. 4: 919-28. PMID 17874842 DOI: 10.1021/Mp7000846  0.585
2006 Doshi JM, Tian D, Xing C. Structure-activity relationship studies of ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (HA 14-1), an antagonist for antiapoptotic Bcl-2 proteins to overcome drug resistance in cancer. Journal of Medicinal Chemistry. 49: 7731-9. PMID 17181155 DOI: 10.1021/Jm060968R  0.615
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