Susan J. Baserga - Publications

Molecular Biophysics and Biochemistry Yale University School of Medicine, New Haven, CT 

82 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Farley-Barnes KI, McCann KL, Ogawa LM, Merkel J, Surovtseva YV, Baserga SJ. Diverse Regulators of Human Ribosome Biogenesis Discovered by Changes in Nucleolar Number. Cell Reports. 22: 1923-1934. PMID 29444442 DOI: 10.1016/j.celrep.2018.01.056  0.4
2017 Vincent NG, Charette JM, Baserga SJ. The SSU processome interactome in Saccharomyces cerevisiae reveals potential new protein subcomplexes. Rna (New York, N.Y.). PMID 29054886 DOI: 10.1261/rna.062927.117  1
2017 Boyden LM, Vincent NG, Zhou J, Hu R, Craiglow BG, Bayliss SJ, Rosman IS, Lucky AW, Diaz LA, Goldsmith LA, Paller AS, Lifton RP, Baserga SJ, Choate KA. Mutations in KDSR Cause Recessive Progressive Symmetric Erythrokeratoderma. American Journal of Human Genetics. 100: 978-984. PMID 28575652 DOI: 10.1016/j.ajhg.2017.05.003  0.6
2017 Paolini NA, Attwood M, Sondalle SB, Vieira CM, van Adrichem AM, di Summa FM, O'Donohue MF, Gleizes PE, Rachuri S, Briggs JW, Fischer R, Ratcliffe PJ, Wlodarski MW, Houtkooper RH, von Lindern M, ... ... Baserga SJ, et al. A Ribosomopathy Reveals Decoding Defective Ribosomes Driving Human Dysmorphism. American Journal of Human Genetics. 100: 506-522. PMID 28257692 DOI: 10.1016/j.ajhg.2017.01.034  0.64
2016 Zhang J, McCann KL, Qiu C, Gonzalez LE, Baserga SJ, Hall TM. Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA. Nature Communications. 7: 13085. PMID 27725644 DOI: 10.1038/ncomms13085  0.4
2016 Yip WS, Shigematsu H, Taylor DW, Baserga SJ. Box C/D sRNA stem ends act as stabilizing anchors for box C/D di-sRNPs. Nucleic Acids Research. PMID 27342279 DOI: 10.1093/nar/gkw576  1
2015 McCann KL, Charette JM, Vincent NG, Baserga SJ. A protein interaction map of the LSU processome. Genes & Development. 29: 862-75. PMID 25877921 DOI: 10.1101/gad.256370.114  1
2015 Griffin JN, Sondalle SB, Del Viso F, Baserga SJ, Khokha MK. The ribosome biogenesis factor Nol11 is required for optimal rDNA transcription and craniofacial development in Xenopus. Plos Genetics. 11: e1005018. PMID 25756904 DOI: 10.1371/journal.pgen.1005018  1
2015 Farley KI, Surovtseva Y, Merkel J, Baserga SJ. Determinants of mammalian nucleolar architecture. Chromosoma. PMID 25670395 DOI: 10.1007/s00412-015-0507-z  1
2014 Qiu C, McCann KL, Wine RN, Baserga SJ, Hall TM. A divergent Pumilio repeat protein family for pre-rRNA processing and mRNA localization. Proceedings of the National Academy of Sciences of the United States of America. 111: 18554-9. PMID 25512524 DOI: 10.1073/pnas.1407634112  1
2014 Zhao C, Andreeva V, Gibert Y, LaBonty M, Lattanzi V, Prabhudesai S, Zhou Y, Zon L, McCann KL, Baserga S, Yelick PC. Tissue specific roles for the ribosome biogenesis factor Wdr43 in zebrafish development. Plos Genetics. 10: e1004074. PMID 24497835 DOI: 10.1371/journal.pgen.1004074  1
2014 McCann KL, Baserga SJ. Driving nucleolar assembly. Genes & Development. 28: 211-3. PMID 24493643 DOI: 10.1101/gad.237610.114  1
2014 Sondalle SB, Baserga SJ. Human diseases of the SSU processome. Biochimica Et Biophysica Acta. 1842: 758-64. PMID 24240090 DOI: 10.1016/j.bbadis.2013.11.004  1
2014 Yip WSV, Shigematsu H, Taylor DW, Wang HW, Baserga SJ. Cryo-electron microscopic study of the enzymatic mechanism of the RNA 2'-O-methyltransferase Box C\D sRNP Microscopy and Microanalysis. 20: 1284-1285. DOI: 10.1017/S1431927614008150  1
2014 McCann KL, Baserga SJ. Making ribosomes: Pre-rRNA transcription and processing Fungal Rna Biology. 217-232. DOI: 10.1007/978-3-319-05687-6_9  1
2013 Woolford JL, Baserga SJ. Ribosome biogenesis in the yeast Saccharomyces cerevisiae. Genetics. 195: 643-81. PMID 24190922 DOI: 10.1534/genetics.113.153197  1
2013 McCann KL, Baserga SJ. Genetics. Mysterious ribosomopathies. Science (New York, N.Y.). 341: 849-50. PMID 23970686 DOI: 10.1126/science.1244156  1
2013 Yip WS, Vincent NG, Baserga SJ. Ribonucleoproteins in archaeal pre-rRNA processing and modification. Archaea (Vancouver, B.C.). 2013: 614735. PMID 23554567 DOI: 10.1155/2013/614735  1
2012 McCann KL, Baserga SJ. Long noncoding RNAs as sinks in Prader-Willi syndrome. Molecular Cell. 48: 155-7. PMID 23102265 DOI: 10.1016/j.molcel.2012.10.005  1
2012 Freed EF, Prieto JL, McCann KL, McStay B, Baserga SJ. NOL11, implicated in the pathogenesis of North American Indian childhood cirrhosis, is required for pre-rRNA transcription and processing. Plos Genetics. 8: e1002892. PMID 22916032 DOI: 10.1371/journal.pgen.1002892  1
2012 Richardson LA, Reed BJ, Charette JM, Freed EF, Fredrickson EK, Locke MN, Baserga SJ, Gardner RG. A conserved deubiquitinating enzyme controls cell growth by regulating RNA polymerase I stability. Cell Reports. 2: 372-85. PMID 22902402 DOI: 10.1016/j.celrep.2012.07.009  1
2012 Bower-Phipps KR, Taylor DW, Wang HW, Baserga SJ. The box C/D sRNP dimeric architecture is conserved across domain Archaea. Rna (New York, N.Y.). 18: 1527-40. PMID 22753779 DOI: 10.1261/rna.033134.112  1
2012 Rawling DC, Baserga SJ. In vivo approaches to dissecting the function of RNA helicases in eukaryotic ribosome assembly. Methods in Enzymology. 511: 289-321. PMID 22713326 DOI: 10.1016/B978-0-12-396546-2.00014-0  1
2011 Lim YH, Charette JM, Baserga SJ. Assembling a protein-protein interaction map of the SSU processome from existing datasets. Plos One. 6: e17701. PMID 21423703 DOI: 10.1371/journal.pone.0017701  1
2011 Dutca LM, Gallagher JE, Baserga SJ. The initial U3 snoRNA:pre-rRNA base pairing interaction required for pre-18S rRNA folding revealed by in vivo chemical probing. Nucleic Acids Research. 39: 5164-80. PMID 21349877 DOI: 10.1093/nar/gkr044  1
2011 Phipps KR, Charette J, Baserga SJ. The small subunit processome in ribosome biogenesis—progress and prospects. Wiley Interdisciplinary Reviews. Rna. 2: 1-21. PMID 21318072 DOI: 10.1002/wrna.57  1
2011 Bleichert F, Baserga S. Small ribonucleoproteins in ribosome biogenesis Protein Reviews. 15: 135-156. DOI: 10.1007/978-1-4614-0514-6-7  1
2010 Charette JM, Baserga SJ. The DEAD-box RNA helicase-like Utp25 is an SSU processome component. Rna (New York, N.Y.). 16: 2156-69. PMID 20884785 DOI: 10.1261/rna.2359810  1
2010 Bleichert F, Baserga SJ. Dissecting the role of conserved box C/D sRNA sequences in di-sRNP assembly and function. Nucleic Acids Research. 38: 8295-305. PMID 20693534 DOI: 10.1093/nar/gkq690  1
2010 Bleichert F, Baserga SJ. Ribonucleoprotein multimers and their functions. Critical Reviews in Biochemistry and Molecular Biology. 45: 331-50. PMID 20572804 DOI: 10.3109/10409238.2010.496772  1
2010 Freed EF, Baserga SJ. The C-terminus of Utp4, mutated in childhood cirrhosis, is essential for ribosome biogenesis. Nucleic Acids Research. 38: 4798-806. PMID 20385600 DOI: 10.1093/nar/gkq185  1
2010 Freed EF, Bleichert F, Dutca LM, Baserga SJ. When ribosomes go bad: diseases of ribosome biogenesis. Molecular Biosystems. 6: 481-93. PMID 20174677 DOI: 10.1039/b919670f  1
2009 Bleichert F, Gagnon KT, Brown BA, Maxwell ES, Leschziner AE, Unger VM, Baserga SJ. A dimeric structure for archaeal box C/D small ribonucleoproteins. Science (New York, N.Y.). 325: 1384-7. PMID 19745151 DOI: 10.1126/science.1176099  1
2009 Champion EA, Kundrat L, Regan L, Baserga SJ. A structural model for the HAT domain of Utp6 incorporating bioinformatics and genetics. Protein Engineering, Design & Selection : Peds. 22: 431-9. PMID 19515729 DOI: 10.1093/protein/gzp022  1
2008 Champion EA, Lane BH, Jackrel ME, Regan L, Baserga SJ. A direct interaction between the Utp6 half-a-tetratricopeptide repeat domain and a specific peptide in Utp21 is essential for efficient pre-rRNA processing. Molecular and Cellular Biology. 28: 6547-56. PMID 18725399 DOI: 10.1128/MCB.00906-08  1
2007 Bleichert F, Baserga SJ. The long unwinding road of RNA helicases. Molecular Cell. 27: 339-52. PMID 17679086 DOI: 10.1016/j.molcel.2007.07.014  1
2007 Bernstein KA, Bleichert F, Bean JM, Cross FR, Baserga SJ. Ribosome biogenesis is sensed at the Start cell cycle checkpoint. Molecular Biology of the Cell. 18: 953-64. PMID 17192414 DOI: 10.1091/mbc.E06-06-0512  1
2006 Granneman S, Lin C, Champion EA, Nandineni MR, Zorca C, Baserga SJ. The nucleolar protein Esf2 interacts directly with the DExD/H box RNA helicase, Dbp8, to stimulate ATP hydrolysis. Nucleic Acids Research. 34: 3189-99. PMID 16772403 DOI: 10.1093/nar/gkl419  1
2006 Bleichert F, Granneman S, Osheim YN, Beyer AL, Baserga SJ. The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation. Proceedings of the National Academy of Sciences of the United States of America. 103: 9464-9. PMID 16769905 DOI: 10.1073/pnas.0603673103  1
2006 Zhang X, Champion EA, Tran EJ, Brown BA, Baserga SJ, Maxwell ES. The coiled-coil domain of the Nop56/58 core protein is dispensable for sRNP assembly but is critical for archaeal box C/D sRNP-guided nucleotide methylation. Rna (New York, N.Y.). 12: 1092-103. PMID 16601205 DOI: 10.1261/rna.2230106  1
2006 Bernstein KA, Granneman S, Lee AV, Manickam S, Baserga SJ. Comprehensive mutational analysis of yeast DEXD/H box RNA helicases involved in large ribosomal subunit biogenesis. Molecular and Cellular Biology. 26: 1195-208. PMID 16449635 DOI: 10.1128/MCB.26.4.1195-1208.2006  1
2006 Granneman S, Bernstein KA, Bleichert F, Baserga SJ. Comprehensive mutational analysis of yeast DEXD/H box RNA helicases required for small ribosomal subunit synthesis. Molecular and Cellular Biology. 26: 1183-94. PMID 16449634 DOI: 10.1128/MCB.26.4.1183-1194.2006  1
2006 Champion EA, Baserga SJ. Autoantibody Recognition of Macromolecular Structures and Their Subunits Autoantibodies and Autoimmunity: Molecular Mechanisms in Health and Disease. 379-417. DOI: 10.1002/3527607854.ch17  1
2005 Granneman S, Nandineni MR, Baserga SJ. The putative NTPase Fap7 mediates cytoplasmic 20S pre-rRNA processing through a direct interaction with Rps14. Molecular and Cellular Biology. 25: 10352-64. PMID 16287850 DOI: 10.1128/MCB.25.23.10352-10364.2005  1
2005 Granneman S, Baserga SJ. Crosstalk in gene expression: coupling and co-regulation of rDNA transcription, pre-ribosome assembly and pre-rRNA processing. Current Opinion in Cell Biology. 17: 281-6. PMID 15901498 DOI: 10.1016/  1
2004 Osheim YN, French SL, Keck KM, Champion EA, Spasov K, Dragon F, Baserga SJ, Beyer AL. Pre-18S ribosomal RNA is structurally compacted into the SSU processome prior to being cleaved from nascent transcripts in Saccharomyces cerevisiae. Molecular Cell. 16: 943-54. PMID 15610737 DOI: 10.1016/j.molcel.2004.11.031  1
2004 Bernstein KA, Gallagher JE, Mitchell BM, Granneman S, Baserga SJ. The small-subunit processome is a ribosome assembly intermediate. Eukaryotic Cell. 3: 1619-26. PMID 15590835 DOI: 10.1128/EC.3.6.1619-1626.2004  1
2004 Gallagher JE, Dunbar DA, Granneman S, Mitchell BM, Osheim Y, Beyer AL, Baserga SJ. RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components. Genes & Development. 18: 2506-17. PMID 15489292 DOI: 10.1101/gad.1226604  1
2004 Bernstein KA, Baserga SJ. The small subunit processome is required for cell cycle progression at G1. Molecular Biology of the Cell. 15: 5038-46. PMID 15356263 DOI: 10.1091/mbc.E04-06-0515  1
2004 Granneman S, Baserga SJ. Ribosome biogenesis: of knobs and RNA processing. Experimental Cell Research. 296: 43-50. PMID 15120992 DOI: 10.1016/j.yexcr.2004.03.016  1
2004 Gallagher JE, Baserga SJ. Two-hybrid Mpp10p interaction-defective Imp4 proteins are not interaction defective in vivo but do confer specific pre-rRNA processing defects in Saccharomyces cerevisiae. Nucleic Acids Research. 32: 1404-13. PMID 14990745 DOI: 10.1093/nar/gkh318  1
2003 Granneman S, Baserga SJ. Probing the yeast proteome for RNA-processing factors. Genome Biology. 4: 229. PMID 14519190 DOI: 10.1186/gb-2003-4-10-229  1
2003 Granneman S, Gallagher JE, Vogelzangs J, Horstman W, van Venrooij WJ, Baserga SJ, Pruijn GJ. The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes. Nucleic Acids Research. 31: 1877-87. PMID 12655004 DOI: 10.1093/nar/gkg300  1
2003 Meskauskas A, Baxter JL, Carr EA, Yasenchak J, Gallagher JE, Baserga SJ, Dinman JD. Delayed rRNA processing results in significant ribosome biogenesis and functional defects. Molecular and Cellular Biology. 23: 1602-13. PMID 12588980 DOI: 10.1128/MCB.23.5.1602-1613.2003  1
2002 Wehner KA, Gallagher JE, Baserga SJ. Components of an interdependent unit within the SSU processome regulate and mediate its activity. Molecular and Cellular Biology. 22: 7258-67. PMID 12242301 DOI: 10.1128/MCB.22.20.7258-7267.2002  1
2002 Wehner KA, Ayala L, Kim Y, Young PJ, Hosler BA, Lorson CL, Baserga SJ, Francis JW. Survival motor neuron protein in the nucleolus of mammalian neurons. Brain Research. 945: 160-73. PMID 12126878 DOI: 10.1016/S0006-8993(02)02750-6  1
2002 Dragon F, Gallagher JE, Compagnone-Post PA, Mitchell BM, Porwancher KA, Wehner KA, Wormsley S, Settlage RE, Shabanowitz J, Osheim Y, Beyer AL, Hunt DF, Baserga SJ. A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. Nature. 417: 967-70. PMID 12068309 DOI: 10.1038/nature00769  1
2002 Wehner KA, Baserga SJ. The sigma(70)-like motif: a eukaryotic RNA binding domain unique to a superfamily of proteins required for ribosome biogenesis. Molecular Cell. 9: 329-39. PMID 11864606 DOI: 10.1016/S1097-2765(02)00438-0  1
2001 Yang JM, Baserga SJ, Turley SJ, Pollard KM. Fibrillarin and other snoRNP proteins are targets of autoantibodies in xenobiotic-induced autoimmunity. Clinical Immunology (Orlando, Fla.). 101: 38-50. PMID 11580225 DOI: 10.1006/clim.2001.5099  1
2001 Wormsley S, Samarsky DA, Fournier MJ, Baserga SJ. The 3′-end-processing factor CPSF is required for the splicing of single-intron pre-mRNAS in vivo Rna. 7: 920-931. PMID 11421366 DOI: 10.1017/S1355838201010226  1
2000 Dunbar DA, Dragon F, Lee SJ, Baserga SJ. A nucleolar protein related to ribosomal protein L7 is required for an early step in large ribosomal subunit biogenesis. Proceedings of the National Academy of Sciences of the United States of America. 97: 13027-32. PMID 11087857 DOI: 10.1073/pnas.97.24.13027  1
2000 Dunbar DA, Chen AA, Wormsley S, Baserga SJ. The genes for small nucleolar RNAs in Trypanosoma brucei are organized in clusters and are transcribed as a polycistronic RNA. Nucleic Acids Research. 28: 2855-61. PMID 10908346  1
2000 Dunbar DA, Wormsley S, Lowe TM, Baserga SJ. Fibrillarin-associated box C/D small nucleolar RNAs in Trypanosoma brucei. Sequence conservation and implications for 2'-O-ribose methylation of rRNA. The Journal of Biological Chemistry. 275: 14767-76. PMID 10747997 DOI: 10.1074/jbc.M001180200  1
1999 Lyman SK, Gerace L, Baserga SJ. Human Nop5/Nop58 is a component common to the box C/D small nucleolar ribonucleoproteins. Rna (New York, N.Y.). 5: 1597-604. PMID 10606270 DOI: 10.1017/S1355838299991288  1
1999 Lee SJ, Baserga SJ. Imp3p and Imp4p, two specific components of the U3 small nucleolar ribonucleoprotein that are essential for pre-18S rRNA processing. Molecular and Cellular Biology. 19: 5441-52. PMID 10409734  1
1998 Dunbar DA, Baserga SJ. The U14 snoRNA is required for 2'-O-methylation of the pre-18S rRNA in Xenopus oocytes. Rna (New York, N.Y.). 4: 195-204. PMID 9570319  1
1998 Westendorf JM, Konstantinov KN, Wormsley S, Shu MD, Matsumoto-Taniura N, Pirollet F, Klier FG, Gerace L, Baserga SJ. M phase phosphoprotein 10 is a human U3 small nucleolar ribonucleoprotein component. Molecular Biology of the Cell. 9: 437-49. PMID 9450966  1
1997 Baserga SJ, Agentis TM, Wormsley S, Dunbar DA, Lee S. Mpp10p, a new protein component of the U3 snoRNP required for processing of 18S rRNA precursors. Nucleic Acids Symposium Series. 64-7. PMID 9478208  1
1997 Lee SJ, Baserga SJ. Functional separation of pre-rRNA processing steps revealed by truncation of the U3 small nucleolar ribonucleoprotein component, Mpp10. Proceedings of the National Academy of Sciences of the United States of America. 94: 13536-41. PMID 9391061 DOI: 10.1073/pnas.94.25.13536  1
1997 Dunbar DA, Wormsley S, Agentis TM, Baserga SJ. Mpp10p, a U3 small nucleolar ribonucleoprotein component required for pre-18S rRNA processing in yeast. Molecular and Cellular Biology. 17: 5803-12. PMID 9315638  1
1996 Dunbar DA, Ware VC, Baserga SJ. The U18 snRNA is not essential for pre-rRNA processing in Xenopus laevis. Rna (New York, N.Y.). 2: 324-33. PMID 8634913  1
1995 Baserga SJ, Calhoun DW, Calhoun LH. Ella Clay Wakeman: Yale School of Medicine, 1921. The Yale Journal of Biology and Medicine. 68: 171-90. PMID 8903041  1
1992 Baserga SJ, Gilmore-Hebert M, Yang XW. Distinct molecular signals for nuclear import of the nucleolar snRNA, U3. Genes & Development. 6: 1120-30. PMID 1592260  1
1992 Baserga SJ, Benz EJ. Beta-globin nonsense mutation: deficient accumulation of mRNA occurs despite normal cytoplasmic stability. Proceedings of the National Academy of Sciences of the United States of America. 89: 2935-9. PMID 1557399  1
1991 Baserga SJ, Yang XD, Steitz JA. Three pseudogenes for human U13 snRNA belong to class III. Gene. 107: 347-8. PMID 1748306 DOI: 10.1016/0378-1119(91)90340-H  1
1991 Baserga SJ, Yang XD, Steitz JA. An intact Box C sequence in the U3 snRNA is required for binding of fibrillarin, the protein common to the major family of nucleolar snRNPs. The Embo Journal. 10: 2645-51. PMID 1714385  1
1990 Magnus T, Baserga SJ, Stolle C, Takeshita K, Benz EJ. Metabolism of non-translatable globin mRNAs arising from premature translation termination codons. Annals of the New York Academy of Sciences. 612: 55-66. PMID 2291574 DOI: 10.1111/j.1749-6632.1990.tb24290.x  1
1988 Baserga SJ, Benz EJ. Nonsense mutations in the human beta-globin gene affect mRNA metabolism. Proceedings of the National Academy of Sciences of the United States of America. 85: 2056-60. PMID 3353367 DOI: 10.1073/pnas.85.7.2056  1
1988 Atweh GF, Baserga SJ, Brickner HE. Detecting small mutations in expressed genes by a combination of S1 nuclease and RNase A. Nucleic Acids Research. 16: 8709. PMID 2843823  1
1985 Baserga SJ, Linnenbach AJ, Malcolm S, Ghosh P, Malcolm AD, Takeshita K, Forget BG, Benz EJ. Polyadenylation of a human mitochondrial ribosomal RNA transcript detected by molecular cloning. Gene. 35: 305-12. PMID 4043734 DOI: 10.1016/0378-1119(85)90009-5  1
1980 Rossini M, Baserga S, Huang CH, Ingles CJ, Baserga R. Changes in RNA polymerase II in a cell cycle-specific temperature-sensitive mutant of hamster cells Journal of Cellular Physiology. 103: 97-103. PMID 7191857 DOI: 10.1002/jcp.1041030114  1
1980 Baserga SJ. The early years of coeducation at the Yale University School of Medicine. The Yale Journal of Biology and Medicine. 53: 181-90. PMID 6996342  1
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