Jason M. Ridlon, Ph.D. - Publications

2008 Virginia Commonwealth University, Richmond, VA, United States 
Microbiology Biology, Molecular Biology, Biochemistry

35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ly LK, Rowles JL, Paul HM, Alves JMP, Yemm C, Wolf PM, Devendran S, Hudson ME, Morris DJ, Erdman JW, Ridlon JM. Bacterial steroid-17,20-desmolase is a taxonomically rare enzymatic pathway that converts prednisone to 1,4-androstanediene-3,11,17-trione, a metabolite that causes proliferation of prostate cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 105567. PMID 31870912 DOI: 10.1016/j.jsbmb.2019.105567  0.4
2019 Doden HL, Pollet RM, Mythen SM, Wawrzak Z, Devendran S, Cann I, Koropatkin NM, Ridlon JM. Structural and biochemical characterization of 20β-hydroxysteroid dehydrogenase from strain L2-32. The Journal of Biological Chemistry. PMID 31209107 DOI: 10.1074/jbc.RA119.009390  0.4
2019 Ridlon JM, Devendran S, Alves JM, Doden H, Wolf PG, Pereira GV, Ly L, Volland A, Takei H, Nittono H, Murai T, Kurosawa T, Chlipala GE, Green SJ, Hernandez AG, et al. The ' lifestyle' of bile acid 7α-dehydroxylating bacteria: comparative genomics, metatranscriptomic, and bile acid metabolomics analysis of a defined microbial community in gnotobiotic mice. Gut Microbes. 1-24. PMID 31177942 DOI: 10.1080/19490976.2019.1618173  0.4
2019 Devendran S, Shrestha R, Alves JMP, Wolf PG, Ly L, Hernandez AG, Méndez-García C, Inboden A, Wiley J, Paul O, Allen A, Springer E, Wright CL, Fields CJ, Daniel SL, ... Ridlon JM, et al. ATCC 35704: integration of nutritional requirements, the complete genome sequence, and global transcriptional responses to bile acids. Applied and Environmental Microbiology. PMID 30737348 DOI: 10.1128/AEM.00052-19  0.4
2018 Alexander C, Cross TL, Devendran S, Neumer F, Theis S, Ridlon JM, Suchodolski JS, de Godoy MRC, Swanson KS. Effects of prebiotic inulin-type fructans on blood metabolite and hormone concentrations and faecal microbiota and metabolites in overweight dogs. The British Journal of Nutrition. 1-10. PMID 30064535 DOI: 10.1017/S0007114518001952  0.4
2018 Hylemon PB, Harris SC, Ridlon JM. Metabolism of hydrogen gases and bile acids in the gut microbiome. Febs Letters. PMID 29683480 DOI: 10.1002/1873-3468.13064  0.92
2018 Harris SC, Devendran S, Méndez-García C, Mythen SM, Wright CL, Fields CJ, Hernandez AG, Cann I, Hylemon PB, Ridlon JM. Bile acid oxidation by Eggerthella lenta strains C592 and DSM 2243. Gut Microbes. 1-58. PMID 29617190 DOI: 10.1080/19490976.2018.1458180  0.92
2018 Devendran S, Mythen SM, Ridlon JM. The desA and desB genes from Clostridium scindens ATCC 35704 encode steroid-17,20-desmolase. Journal of Lipid Research. PMID 29572237 DOI: 10.1194/jlr.M083949  0.4
2018 Doden H, Sallam LA, Devendran S, Ly L, Doden G, Daniel SL, Alves JMP, Ridlon JM. Metabolism of oxo-bile acids and characterization of recombinant 12α-hydroxysteroid dehydrogenases from bile acid 7α-dehydroxylating human gut bacteriaATCC 35704,DSM 15053 andDSM 13275. Applied and Environmental Microbiology. PMID 29549099 DOI: 10.1128/AEM.00235-18  0.4
2018 Mythen SM, Devendran S, Méndez-García C, Cann I, Ridlon JM. Targeted synthesis and characterization of a gene-cluster encoding NAD(P)H-dependent 3α-, 3β-, and 12α-hydroxysteroid dehydrogenases from Eggerthella CAG:298, a gut metagenomic sequence. Applied and Environmental Microbiology. PMID 29330189 DOI: 10.1128/AEM.02475-17  0.4
2017 Harris SC, Devendran S, Alves JMP, Mythen SM, Hylemon PB, Ridlon JM. Identification of a gene encoding a flavoprotein involved in bile acid metabolism by the human gut bacterium Clostridium scindens ATCC 35704. Biochimica Et Biophysica Acta. PMID 29217478 DOI: 10.1016/j.bbalip.2017.12.001  0.92
2017 Devendran S, Méndez-Garcia C, Ridlon JM. Identification and characterization of a 20β-hydroxysteroid dehydrogenase from the anaerobic gut bacterium Butyricicoccus desmolans ATCC 43058. Journal of Lipid Research. PMID 28314858 DOI: 10.1194/jlr.M074914  0.4
2016 Ridlon JM, Wolf PG, Gaskins HR. Taurocholic Acid Metabolism by Gut Microbes and Colon Cancer. Gut Microbes. 0. PMID 27003186 DOI: 10.1080/19490976.2016.1150414  0.92
2016 Ridlon JM, Harris SC, Bhowmik S, Kang DJ, Hylemon PB. Consequences of bile salt biotransformations by intestinal bacteria. Gut Microbes. 7: 22-39. PMID 26939849 DOI: 10.1080/19490976.2015.1127483  0.92
2015 Bhowmik S, Chiu HP, Jones DH, Chiu HJ, Miller MD, Xu Q, Farr CL, Ridlon JM, Wells JE, Elsliger MA, Wilson IA, Hylemon PB, Lesley SA. Structure and Functional Characterization of a Bile Acid 7α Dehydratase BaiE in Secondary Bile Acid Synthesis. Proteins. PMID 26650892 DOI: 10.1002/prot.24971  0.92
2015 Ridlon JM, Bajaj JS. The human gut sterolbiome: bile acid-microbiome endocrine aspects and therapeutics. Acta Pharmaceutica Sinica. B. 5: 99-105. PMID 26579434 DOI: 10.1016/j.apsb.2015.01.006  0.92
2015 Ridlon JM, Kang DJ, Hylemon PB, Bajaj JS. Gut microbiota, cirrhosis, and alcohol regulate bile acid metabolism in the gut. Digestive Diseases (Basel, Switzerland). 33: 338-45. PMID 26045267 DOI: 10.1159/000371678  0.92
2015 Gu S, Cao B, Sun R, Tang Y, Paletta JL, Wu XL, Liu L, Zha W, Zhao C, Li Y, Ridlon JM, Hylemon PB, Zhou H, Aa J, Wang G. Correction: A metabolomic and pharmacokinetic study on the mechanism underlying the lipid-lowering effect of orally administered berberine. Molecular Biosystems. 11: 664. PMID 26039924 DOI: 10.1039/c4mb90042a  0.92
2015 Gu S, Cao B, Sun R, Tang Y, Paletta JL, Wu XL, Liu L, Zha W, Zhao C, Li Y, Ridlon JM, Hylemon PB, Zhou H, Aa J, Wang G. Correction: A metabolomic and pharmacokinetic study on the mechanism underlying the lipid-lowering effect of orally administered berberine. Molecular Biosystems. 11: 664. PMID 25535027 DOI: 10.1039/c4mb90042a  0.92
2014 Kakiyama G, Hylemon PB, Zhou H, Pandak WM, Heuman DM, Kang DJ, Takei H, Nittono H, Ridlon JM, Fuchs M, Gurley EC, Wang Y, Liu R, Sanyal AJ, Gillevet PM, et al. Colonic inflammation and secondary bile acids in alcoholic cirrhosis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 306: G929-37. PMID 24699327 DOI: 10.1152/ajpgi.00315.2013  0.92
2014 Ridlon JM, Kang DJ, Hylemon PB, Bajaj JS. Bile acids and the gut microbiome. Current Opinion in Gastroenterology. 30: 332-8. PMID 24625896 DOI: 10.1097/MOG.0000000000000057  0.92
2013 Ridlon JM, Alves JM, Hylemon PB, Bajaj JS. Cirrhosis, bile acids and gut microbiota: unraveling a complex relationship. Gut Microbes. 4: 382-7. PMID 23851335 DOI: 10.4161/gmic.25723  0.92
2013 Ridlon JM, Ikegawa S, Alves JM, Zhou B, Kobayashi A, Iida T, Mitamura K, Tanabe G, Serrano M, De Guzman A, Cooper P, Buck GA, Hylemon PB. Clostridium scindens: a human gut microbe with a high potential to convert glucocorticoids into androgens. Journal of Lipid Research. 54: 2437-49. PMID 23772041 DOI: 10.1194/jlr.M038869  0.92
2013 Bajaj JS, Heuman DM, Sanyal AJ, Hylemon PB, Sterling RK, Stravitz RT, Fuchs M, Ridlon JM, Daita K, Monteith P, Noble NA, White MB, Fisher A, Sikaroodi M, Rangwala H, et al. Modulation of the metabiome by rifaximin in patients with cirrhosis and minimal hepatic encephalopathy. Plos One. 8: e60042. PMID 23565181 DOI: 10.1371/journal.pone.0060042  0.92
2013 Kakiyama G, Pandak WM, Gillevet PM, Hylemon PB, Heuman DM, Daita K, Takei H, Muto A, Nittono H, Ridlon JM, White MB, Noble NA, Monteith P, Fuchs M, Thacker LR, et al. Modulation of the fecal bile acid profile by gut microbiota in cirrhosis. Journal of Hepatology. 58: 949-55. PMID 23333527 DOI: 10.1016/j.jhep.2013.01.003  0.92
2012 Bajaj JS, Hylemon PB, Ridlon JM, Heuman DM, Daita K, White MB, Monteith P, Noble NA, Sikaroodi M, Gillevet PM. Colonic mucosal microbiome differs from stool microbiome in cirrhosis and hepatic encephalopathy and is linked to cognition and inflammation. American Journal of Physiology. Gastrointestinal and Liver Physiology. 303: G675-85. PMID 22821944 DOI: 10.1152/ajpgi.00152.2012  0.92
2012 Bajaj JS, Gillevet PM, Patel NR, Ahluwalia V, Ridlon JM, Kettenmann B, Schubert CM, Sikaroodi M, Heuman DM, Crossey MM, Bell DE, Hylemon PB, Fatouros PP, Taylor-Robinson SD. A longitudinal systems biology analysis of lactulose withdrawal in hepatic encephalopathy. Metabolic Brain Disease. 27: 205-15. PMID 22527995 DOI: 10.1007/s11011-012-9303-0  0.92
2012 Ridlon JM, Hylemon PB. Identification and characterization of two bile acid coenzyme A transferases from Clostridium scindens, a bile acid 7α-dehydroxylating intestinal bacterium. Journal of Lipid Research. 53: 66-76. PMID 22021638 DOI: 10.1194/jlr.M020313  0.92
2012 Bajaj JS, Ridlon JM, Hylemon PB, Thacker LR, Heuman DM, Smith S, Sikaroodi M, Gillevet PM. Linkage of gut microbiome with cognition in hepatic encephalopathy. American Journal of Physiology. Gastrointestinal and Liver Physiology. 302: G168-75. PMID 21940902 DOI: 10.1152/ajpgi.00190.2011  0.92
2010 Ridlon JM, Kang DJ, Hylemon PB. Isolation and characterization of a bile acid inducible 7alpha-dehydroxylating operon in Clostridium hylemonae TN271. Anaerobe. 16: 137-46. PMID 19464381 DOI: 10.1016/j.anaerobe.2009.05.004  0.92
2008 Kang DJ, Ridlon JM, Moore DR, Barnes S, Hylemon PB. Clostridium scindens baiCD and baiH genes encode stereo-specific 7alpha/7beta-hydroxy-3-oxo-delta4-cholenoic acid oxidoreductases. Biochimica Et Biophysica Acta. 1781: 16-25. PMID 18047844 DOI: 10.1016/j.bbalip.2007.10.008  0.92
2006 Ridlon JM, Hylemon PB. A potential role for resistant starch fermentation in modulating colonic bacterial metabolism and colon cancer risk. Cancer Biology & Therapy. 5: 273-4. PMID 16627972  0.92
2006 Ridlon JM, Kang DJ, Hylemon PB. Bile salt biotransformations by human intestinal bacteria. Journal of Lipid Research. 47: 241-59. PMID 16299351 DOI: 10.1194/jlr.R500013-JLR200  0.92
2005 Ridlon JM, McGarr SE, Hylemon PB. Development of methods for the detection and quantification of 7alpha-dehydroxylating clostridia, Desulfovibrio vulgaris, Methanobrevibacter smithii, and Lactobacillus plantarum in human feces. Clinica Chimica Acta; International Journal of Clinical Chemistry. 357: 55-64. PMID 15963794 DOI: 10.1016/j.cccn.2005.02.004  0.92
2005 McGarr SE, Ridlon JM, Hylemon PB. Diet, anaerobic bacterial metabolism, and colon cancer: a review of the literature. Journal of Clinical Gastroenterology. 39: 98-109. PMID 15681903  0.92
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