Jason M. Ridlon, Ph.D. - Publications

Affiliations: 
2008 Virginia Commonwealth University, Richmond, VA, United States 
Area:
Microbiology Biology, Molecular Biology, Biochemistry

35/59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ly LK, Rowles JL, Paul HM, Alves JMP, Yemm C, Wolf PM, Devendran S, Hudson ME, Morris DJ, Erdman JW, Ridlon JM. Bacterial steroid-17,20-desmolase is a taxonomically rare enzymatic pathway that converts prednisone to 1,4-androstanediene-3,11,17-trione, a metabolite that causes proliferation of prostate cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 105567. PMID 31870912 DOI: 10.1016/j.jsbmb.2019.105567  0.4
2019 Doden HL, Pollet RM, Mythen SM, Wawrzak Z, Devendran S, Cann I, Koropatkin NM, Ridlon JM. Structural and biochemical characterization of 20β-hydroxysteroid dehydrogenase from strain L2-32. The Journal of Biological Chemistry. PMID 31209107 DOI: 10.1074/jbc.RA119.009390  0.4
2019 Ridlon JM, Devendran S, Alves JM, Doden H, Wolf PG, Pereira GV, Ly L, Volland A, Takei H, Nittono H, Murai T, Kurosawa T, Chlipala GE, Green SJ, Hernandez AG, et al. The ' lifestyle' of bile acid 7α-dehydroxylating bacteria: comparative genomics, metatranscriptomic, and bile acid metabolomics analysis of a defined microbial community in gnotobiotic mice. Gut Microbes. 1-24. PMID 31177942 DOI: 10.1080/19490976.2019.1618173  0.4
2019 Devendran S, Shrestha R, Alves JMP, Wolf PG, Ly L, Hernandez AG, Méndez-García C, Inboden A, Wiley J, Paul O, Allen A, Springer E, Wright CL, Fields CJ, Daniel SL, ... Ridlon JM, et al. ATCC 35704: integration of nutritional requirements, the complete genome sequence, and global transcriptional responses to bile acids. Applied and Environmental Microbiology. PMID 30737348 DOI: 10.1128/AEM.00052-19  0.4
2018 Alexander C, Cross TL, Devendran S, Neumer F, Theis S, Ridlon JM, Suchodolski JS, de Godoy MRC, Swanson KS. Effects of prebiotic inulin-type fructans on blood metabolite and hormone concentrations and faecal microbiota and metabolites in overweight dogs. The British Journal of Nutrition. 1-10. PMID 30064535 DOI: 10.1017/S0007114518001952  0.4
2018 Hylemon PB, Harris SC, Ridlon JM. Metabolism of hydrogen gases and bile acids in the gut microbiome. Febs Letters. PMID 29683480 DOI: 10.1002/1873-3468.13064  0.92
2018 Harris SC, Devendran S, Méndez-García C, Mythen SM, Wright CL, Fields CJ, Hernandez AG, Cann I, Hylemon PB, Ridlon JM. Bile acid oxidation by Eggerthella lenta strains C592 and DSM 2243. Gut Microbes. 1-58. PMID 29617190 DOI: 10.1080/19490976.2018.1458180  0.92
2018 Devendran S, Mythen SM, Ridlon JM. The desA and desB genes from Clostridium scindens ATCC 35704 encode steroid-17,20-desmolase. Journal of Lipid Research. PMID 29572237 DOI: 10.1194/jlr.M083949  0.4
2018 Doden H, Sallam LA, Devendran S, Ly L, Doden G, Daniel SL, Alves JMP, Ridlon JM. Metabolism of oxo-bile acids and characterization of recombinant 12α-hydroxysteroid dehydrogenases from bile acid 7α-dehydroxylating human gut bacteriaATCC 35704,DSM 15053 andDSM 13275. Applied and Environmental Microbiology. PMID 29549099 DOI: 10.1128/AEM.00235-18  0.4
2018 Mythen SM, Devendran S, Méndez-García C, Cann I, Ridlon JM. Targeted synthesis and characterization of a gene-cluster encoding NAD(P)H-dependent 3α-, 3β-, and 12α-hydroxysteroid dehydrogenases from Eggerthella CAG:298, a gut metagenomic sequence. Applied and Environmental Microbiology. PMID 29330189 DOI: 10.1128/AEM.02475-17  0.4
2017 Harris SC, Devendran S, Alves JMP, Mythen SM, Hylemon PB, Ridlon JM. Identification of a gene encoding a flavoprotein involved in bile acid metabolism by the human gut bacterium Clostridium scindens ATCC 35704. Biochimica Et Biophysica Acta. PMID 29217478 DOI: 10.1016/j.bbalip.2017.12.001  0.92
2017 Devendran S, Méndez-Garcia C, Ridlon JM. Identification and characterization of a 20β-hydroxysteroid dehydrogenase from the anaerobic gut bacterium Butyricicoccus desmolans ATCC 43058. Journal of Lipid Research. PMID 28314858 DOI: 10.1194/jlr.M074914  0.4
2016 Ridlon JM, Wolf PG, Gaskins HR. Taurocholic Acid Metabolism by Gut Microbes and Colon Cancer. Gut Microbes. 0. PMID 27003186 DOI: 10.1080/19490976.2016.1150414  0.92
2016 Ridlon JM, Harris SC, Bhowmik S, Kang DJ, Hylemon PB. Consequences of bile salt biotransformations by intestinal bacteria. Gut Microbes. 7: 22-39. PMID 26939849 DOI: 10.1080/19490976.2015.1127483  0.92
2015 Bhowmik S, Chiu HP, Jones DH, Chiu HJ, Miller MD, Xu Q, Farr CL, Ridlon JM, Wells JE, Elsliger MA, Wilson IA, Hylemon PB, Lesley SA. Structure and Functional Characterization of a Bile Acid 7α Dehydratase BaiE in Secondary Bile Acid Synthesis. Proteins. PMID 26650892 DOI: 10.1002/prot.24971  0.92
2015 Ridlon JM, Bajaj JS. The human gut sterolbiome: bile acid-microbiome endocrine aspects and therapeutics. Acta Pharmaceutica Sinica. B. 5: 99-105. PMID 26579434 DOI: 10.1016/j.apsb.2015.01.006  0.92
2015 Ridlon JM, Kang DJ, Hylemon PB, Bajaj JS. Gut microbiota, cirrhosis, and alcohol regulate bile acid metabolism in the gut. Digestive Diseases (Basel, Switzerland). 33: 338-45. PMID 26045267 DOI: 10.1159/000371678  0.92
2015 Gu S, Cao B, Sun R, Tang Y, Paletta JL, Wu XL, Liu L, Zha W, Zhao C, Li Y, Ridlon JM, Hylemon PB, Zhou H, Aa J, Wang G. Correction: A metabolomic and pharmacokinetic study on the mechanism underlying the lipid-lowering effect of orally administered berberine. Molecular Biosystems. 11: 664. PMID 26039924 DOI: 10.1039/c4mb90042a  0.92
2015 Gu S, Cao B, Sun R, Tang Y, Paletta JL, Wu XL, Liu L, Zha W, Zhao C, Li Y, Ridlon JM, Hylemon PB, Zhou H, Aa J, Wang G. Correction: A metabolomic and pharmacokinetic study on the mechanism underlying the lipid-lowering effect of orally administered berberine. Molecular Biosystems. 11: 664. PMID 25535027 DOI: 10.1039/c4mb90042a  0.92
2014 Kakiyama G, Hylemon PB, Zhou H, Pandak WM, Heuman DM, Kang DJ, Takei H, Nittono H, Ridlon JM, Fuchs M, Gurley EC, Wang Y, Liu R, Sanyal AJ, Gillevet PM, et al. Colonic inflammation and secondary bile acids in alcoholic cirrhosis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 306: G929-37. PMID 24699327 DOI: 10.1152/ajpgi.00315.2013  0.92
2014 Ridlon JM, Kang DJ, Hylemon PB, Bajaj JS. Bile acids and the gut microbiome. Current Opinion in Gastroenterology. 30: 332-8. PMID 24625896 DOI: 10.1097/MOG.0000000000000057  0.92
2013 Ridlon JM, Alves JM, Hylemon PB, Bajaj JS. Cirrhosis, bile acids and gut microbiota: unraveling a complex relationship. Gut Microbes. 4: 382-7. PMID 23851335 DOI: 10.4161/gmic.25723  0.92
2013 Ridlon JM, Ikegawa S, Alves JM, Zhou B, Kobayashi A, Iida T, Mitamura K, Tanabe G, Serrano M, De Guzman A, Cooper P, Buck GA, Hylemon PB. Clostridium scindens: a human gut microbe with a high potential to convert glucocorticoids into androgens. Journal of Lipid Research. 54: 2437-49. PMID 23772041 DOI: 10.1194/jlr.M038869  0.92
2013 Bajaj JS, Heuman DM, Sanyal AJ, Hylemon PB, Sterling RK, Stravitz RT, Fuchs M, Ridlon JM, Daita K, Monteith P, Noble NA, White MB, Fisher A, Sikaroodi M, Rangwala H, et al. Modulation of the metabiome by rifaximin in patients with cirrhosis and minimal hepatic encephalopathy. Plos One. 8: e60042. PMID 23565181 DOI: 10.1371/journal.pone.0060042  0.92
2013 Kakiyama G, Pandak WM, Gillevet PM, Hylemon PB, Heuman DM, Daita K, Takei H, Muto A, Nittono H, Ridlon JM, White MB, Noble NA, Monteith P, Fuchs M, Thacker LR, et al. Modulation of the fecal bile acid profile by gut microbiota in cirrhosis. Journal of Hepatology. 58: 949-55. PMID 23333527 DOI: 10.1016/j.jhep.2013.01.003  0.92
2012 Bajaj JS, Hylemon PB, Ridlon JM, Heuman DM, Daita K, White MB, Monteith P, Noble NA, Sikaroodi M, Gillevet PM. Colonic mucosal microbiome differs from stool microbiome in cirrhosis and hepatic encephalopathy and is linked to cognition and inflammation. American Journal of Physiology. Gastrointestinal and Liver Physiology. 303: G675-85. PMID 22821944 DOI: 10.1152/ajpgi.00152.2012  0.92
2012 Bajaj JS, Gillevet PM, Patel NR, Ahluwalia V, Ridlon JM, Kettenmann B, Schubert CM, Sikaroodi M, Heuman DM, Crossey MM, Bell DE, Hylemon PB, Fatouros PP, Taylor-Robinson SD. A longitudinal systems biology analysis of lactulose withdrawal in hepatic encephalopathy. Metabolic Brain Disease. 27: 205-15. PMID 22527995 DOI: 10.1007/s11011-012-9303-0  0.92
2012 Ridlon JM, Hylemon PB. Identification and characterization of two bile acid coenzyme A transferases from Clostridium scindens, a bile acid 7α-dehydroxylating intestinal bacterium. Journal of Lipid Research. 53: 66-76. PMID 22021638 DOI: 10.1194/jlr.M020313  0.92
2012 Bajaj JS, Ridlon JM, Hylemon PB, Thacker LR, Heuman DM, Smith S, Sikaroodi M, Gillevet PM. Linkage of gut microbiome with cognition in hepatic encephalopathy. American Journal of Physiology. Gastrointestinal and Liver Physiology. 302: G168-75. PMID 21940902 DOI: 10.1152/ajpgi.00190.2011  0.92
2010 Ridlon JM, Kang DJ, Hylemon PB. Isolation and characterization of a bile acid inducible 7alpha-dehydroxylating operon in Clostridium hylemonae TN271. Anaerobe. 16: 137-46. PMID 19464381 DOI: 10.1016/j.anaerobe.2009.05.004  0.92
2008 Kang DJ, Ridlon JM, Moore DR, Barnes S, Hylemon PB. Clostridium scindens baiCD and baiH genes encode stereo-specific 7alpha/7beta-hydroxy-3-oxo-delta4-cholenoic acid oxidoreductases. Biochimica Et Biophysica Acta. 1781: 16-25. PMID 18047844 DOI: 10.1016/j.bbalip.2007.10.008  0.92
2006 Ridlon JM, Hylemon PB. A potential role for resistant starch fermentation in modulating colonic bacterial metabolism and colon cancer risk. Cancer Biology & Therapy. 5: 273-4. PMID 16627972  0.92
2006 Ridlon JM, Kang DJ, Hylemon PB. Bile salt biotransformations by human intestinal bacteria. Journal of Lipid Research. 47: 241-59. PMID 16299351 DOI: 10.1194/jlr.R500013-JLR200  0.92
2005 Ridlon JM, McGarr SE, Hylemon PB. Development of methods for the detection and quantification of 7alpha-dehydroxylating clostridia, Desulfovibrio vulgaris, Methanobrevibacter smithii, and Lactobacillus plantarum in human feces. Clinica Chimica Acta; International Journal of Clinical Chemistry. 357: 55-64. PMID 15963794 DOI: 10.1016/j.cccn.2005.02.004  0.92
2005 McGarr SE, Ridlon JM, Hylemon PB. Diet, anaerobic bacterial metabolism, and colon cancer: a review of the literature. Journal of Clinical Gastroenterology. 39: 98-109. PMID 15681903  0.92
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2015 Gu S, Cao B, Sun R, Tang Y, Paletta JL, Wu XL, Liu L, Zha W, Zhao C, Li Y, Radlon JM, Hylemon PB, Zhou H, Aa J, Wang G. A metabolomic and pharmacokinetic study on the mechanism underlying the lipid-lowering effect of orally administered berberine. Molecular Biosystems. 11: 463-74. PMID 25411028 DOI: 10.1039/c4mb00500g  0.08
2020 Campbell DE, Ly LK, Ridlon JM, Hsiao A, Whitaker RJ, Degnan PH. Infection with Bacteroides Phage BV01 Alters the Host Transcriptome and Bile Acid Metabolism in a Common Human Gut Microbe. Cell Reports. 32: 108142. PMID 32937127 DOI: 10.1016/j.celrep.2020.108142  0.01
2020 Wolf PG, Gaskins HR, Ridlon JM, Freels S, Hamm A, Goldberg S, Petrilli P, Schering T, Vergis S, Gomez-Perez S, Yazici C, Braunschweig C, Mutlu E, Tussing-Humphreys L. Effects of taurocholic acid metabolism by gut bacteria: A controlled feeding trial in adult African American subjects at elevated risk for colorectal cancer. Contemporary Clinical Trials Communications. 19: 100611. PMID 32695922 DOI: 10.1016/j.conctc.2020.100611  0.01
2020 Ridlon JM. Conceptualizing the vertebrate sterolbiome. Applied and Environmental Microbiology. PMID 32503912 DOI: 10.1128/AEM.00641-20  0.01
2020 Xavier JB, Young VB, Skufca J, Ginty F, Testerman T, Pearson AT, Macklin P, Mitchell A, Shmulevich I, Xie L, Caporaso JG, Crandall KA, Simone NL, Godoy-Vitorino F, Griffin TJ, ... ... Ridlon JM, et al. The Cancer Microbiome: Distinguishing Direct and Indirect Effects Requires a Systemic View. Trends in Cancer. 6: 192-204. PMID 32101723 DOI: 10.1016/j.trecan.2020.01.004  0.01
2020 Wolf PG, Gaskins HR, Ridlon JM, Freels S, Hamm A, Goldberg S, Petrilli P, Schering T, Vergis S, Gomez-Perez S, Yazici C, Braunschweig C, Mutlu E, Tussing-Humphreys L. Effects of taurocholic acid metabolism by gut bacteria: A controlled feeding trial in adult African American subjects at elevated risk for colorectal cancer Contemporary Clinical Trials Communications. 19: 100611. DOI: 10.1016/j.conctc.2020.100611  0.01
2019 Alexander C, Ridlon J, Swanson K. Cholecystectomy and Postprandial Psyllium Husk Fiber Consumption Alter the Gastrointestinal Microbiota Community in a Post-menopausal Mouse Model (P20-028-19). Current Developments in Nutrition. 3. PMID 31225222 DOI: 10.1093/cdn/nzz040.P20-028-19  0.01
2019 Alexander C, Ly L, He S, Ridlon JM, Nelson ER, Swanson KS. 448 – Cholecystectomy Alters Gastrointestinal Health Indices and Exacerbates Post-Menopausal Metabolic Dysfunction in a Mouse Model Consuming a High Fat Diet Gastroenterology. 156: S-94. DOI: 10.1016/S0016-5085(19)37021-0  0.01
2018 Hale VL, Jeraldo P, Chen J, Mundy M, Yao J, Priya S, Keeney G, Lyke K, Ridlon J, White BA, French AJ, Thibodeau SN, Diener C, Resendis-Antonio O, Gransee J, et al. Distinct microbes, metabolites, and ecologies define the microbiome in deficient and proficient mismatch repair colorectal cancers. Genome Medicine. 10: 78. PMID 30376889 DOI: 10.1186/s13073-018-0586-6  0.01
2018 Hernandez J, Volland A, Leyshon BJ, Juda M, Ridlon JM, Johnson RW, Steelman AJ. Effect of imidacloprid ingestion on immune responses to porcine reproductive and respiratory syndrome virus. Scientific Reports. 8: 11615. PMID 30072754 DOI: 10.1038/s41598-018-30093-6  0.01
2018 Ridlon JM, Doden H, Ly L, Volland A, Mythen S, Devendran S, Sallam L, Pereira G, Cann I, Daniel S, Kakiyama G, Nittono H, Kashyap P, McCracken V, Alves J. Su1939 - Bile Acid 7α-Dehydroxylating Gut Clostridia: From Comparative Genomics to In Vivo Metatranscriptomics and Metabolomics to Gene Discovery Gastroenterology. 154: S-639-S-640. DOI: 10.1016/S0016-5085(18)32285-6  0.01
2018 Harris S, Devendran S, Ridlon JM, Hylemon P. 180 - Eggerthella Lenta Modulates Gut Microbial Physiology by Linking Bile Acid Metabolism to Acetogenesis Gastroenterology. 154: S-46. DOI: 10.1016/S0016-5085(18)30623-1  0.01
2017 Morris DJ, Ridlon JM. Glucocorticoids and gut bacteria: "The GALF Hypothesis" in the metagenomic era. Steroids. PMID 28624548 DOI: 10.1016/j.steroids.2017.06.002  0.01
2015 Kang D, Hylemon P, Sartor R, Kakiyama G, Gillevet P, Heuman D, Pandak W, Ridlon J, Fiehn O, Grapov D, Bajaj J. O090 : Humanization of germ-free mice with alcoholic cirrhotic microbiota, but not healthy microbiota, induces bacterial translocation and a pro-inflammatory milieu, which is ameliorated with lactobacillus GG Journal of Hepatology. 62: S239-S240. DOI: 10.1016/S0168-8278(15)30109-4  0.01
2015 Kang D, Hylemon P, Ridlon JM, Pandak WM, Heuman DM, Bajaj JS. Sa1017 Diminished Fecal Secondary Bile Acids May Predispose Patients With Cirrhosis to C. difficile Infection and Attenuate the Action of Rifaximin Gastroenterology. 148: S-1008. DOI: 10.1016/S0016-5085(15)33439-9  0.01
2015 Kang D, Hylemon P, Sartor RB, Kakiyama G, Gillevet PM, Heuman DM, Pandak WM, Ridlon JM, Grapov D, Fiehn O, Bajaj JS. 281 Humanization of Germ-Free Mice With Alcoholic Cirrhotic Microbiota, but Not Healthy Microbiota, Induces Bacterial Translocation and a Pro-Inflammatory Milieu, Which Is Ameliorated With Lactobacillus GG Gastroenterology. 148: S-975-S-976. DOI: 10.1016/S0016-5085(15)33333-3  0.01
2014 Bajaj J, Heuman D, Hylemon P, Sikaroodi M, Ridlon J, Pandak W, Schubert M, Fuchs M, White M, Daita K, Gillevet P. P335 DYSFUNCTIONAL GUT MICROBIOTA IN ILEO-COLONIC MUCOSA AND STOOL IN ALCOHOLIC CIRRHOSIS IS ASSOCIATED WITH ENDOTOXEMIA: IMPLICATIONS FOR BACTERIAL TRANSLOCATION Journal of Hepatology. 60: S178-S179. DOI: 10.1016/S0168-8278(14)60497-9  0.01
2013 Bajaj J, Heuman D, Sanyal A, Hylemon P, Sterling R, Stravitz R, Fuchs M, Ridlon J, Daita K, Monteith P, White M, Noble N, Fisher A, Sikaroodi M, Rangwala H, et al. 192 RIFAXIMIN IMPROVES COGNITION AND ENDOTOXEMIA IN MINIMAL HEPATIC ENCEPHALOPATHY BY SHIFTING GUT MICROBIAL FUNCTIONALITY WITHOUT ALTERING THEIR ABUNDANCE Journal of Hepatology. 58: S84-S85. DOI: 10.1016/S0168-8278(13)60194-4  0.01
2012 Kakiyama G, Ridlon J, Hylemon P, Pandak W, Gillevet P, Heuman D, Daita K, Bajaj J. 116 THE GUT MICROBIOME MODULATES FECAL BILE ACID PROFILE IN PATIENTS WITH CIRRHOSIS Journal of Hepatology. 56: S51. DOI: 10.1016/S0168-8278(12)60130-5  0.01
2012 Ou J, Ridlon JM, DeLany JP, Vipperla K, Newton K, O'Keefe SJ. Sa1465 Obesity and Colon Cancer Risk: Is it the Fat? Gastroenterology. 142: S-313. DOI: 10.1016/S0016-5085(12)61172-X  0.01
2010 Bajaj J, McPhail M, Heuman D, Bell D, Gillevet P, Sikaroodi M, Sanyal A, Sharif M, Ridlon J, Hylemon P, Taylor-Robinson S. 151 URINARY MAGNETIC RESONANCE SPECTROSCOPY IN PATIENTS WITH HEPATIC ENCEPHALOPATHY: CITRATE CORRELATES WITH ASYMMETRIC DIMETHYLARGININE AND GUT MICROBIAL SPECIES AND CAN PREDICT RECURRENCE AFTER LACTULOSE DISCONTINUATION Journal of Hepatology. 52: S67. DOI: 10.1016/S0168-8278(10)60153-5  0.01
2007 Ridlon J. IV. The Treatment of Fracture of the Neck of the Femur. Annals of Surgery. 34: 61-80. PMID 17861008 DOI: 10.1097/00000658-190107000-00004  0.01
2007 Ridlon J, Jones R. IV. Disease in the Sacro-Iliac Articulation. Annals of Surgery. 17: 285-92. PMID 17859888 DOI: 10.1097/00000658-189301000-00069  0.01
2007 Ridlon J. III. Fractures of the Neck of the Femur: With a Report of Twelve Cases Treated by the Thomas Hip-Splint. Annals of Surgery. 16: 60-73. PMID 17859813 DOI: 10.1097/00000658-189207000-00003  0.01
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