Duane A. Compton - Publications

Affiliations: 
Biochemistry Dartmouth College, Hanover, NH, United States 
Area:
Cell Biology

83 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zhao Y, Carter R, Natarajan S, Varn FS, Compton DA, Gawad C, Cheng C, Godek KM. Single-cell RNA sequencing reveals the impact of chromosomal instability on glioblastoma cancer stem cells. Bmc Medical Genomics. 12: 79. PMID 31151460 DOI: 10.1186/s12920-019-0532-5  0.56
2018 Godek KM, Compton DA. Quantitative methods to measure aneuploidy and chromosomal instability. Methods in Cell Biology. 144: 15-32. PMID 29804667 DOI: 10.1016/bs.mcb.2018.03.002  0.56
2017 Dumitru AMG, Rusin SF, Clark AEM, Kettenbach AN, Compton DA. Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability. Elife. 6. PMID 29154753 DOI: 10.7554/eLife.29303  0.52
2017 Bakhoum SF, Kabeche L, Compton DA, Powell SN, Bastians H. Mitotic DNA Damage Response: At the Crossroads of Structural and Numerical Cancer Chromosome Instabilities. Trends in Cancer. 3: 225-234. PMID 28718433 DOI: 10.1016/j.trecan.2017.02.001  1
2016 Godek KM, Venere M, Wu Q, Mills KD, Hickey WF, Rich JN, Compton DA. Chromosomal instability affects the tumorigenicity of glioblastoma tumor-initiating cells. Cancer Discovery. PMID 27001151 DOI: 10.1158/2159-8290.CD-15-1154  1
2016 Kim JS, He X, Orr B, Wutz G, Hill V, Peters JM, Compton DA, Waldman T. Intact Cohesion, Anaphase, and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations in STAG2. Plos Genetics. 12: e1005865. PMID 26871722 DOI: 10.1371/journal.pgen.1005865  1
2015 Meppelink A, Kabeche L, Vromans MJ, Compton DA, Lens SM. Shugoshin-1 balances Aurora B kinase activity via PP2A to promote chromosome bi-orientation. Cell Reports. 11: 508-15. PMID 25892238 DOI: 10.1016/j.celrep.2015.03.052  1
2015 Hu S, Danilov AV, Godek K, Orr B, Tafe LJ, Rodriguez-Canales J, Behrens C, Mino B, Moran CA, Memoli VA, Mustachio LM, Galimberti F, Ravi S, DeCastro A, Lu Y, ... ... Compton DA, et al. CDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110. Cancer Research. 75: 2029-38. PMID 25808870 DOI: 10.1158/0008-5472.CAN-14-1494  1
2015 Bakhoum SF, Kabeche L, Wood MD, Laucius CD, Qu D, Laughney AM, Reynolds GE, Louie RJ, Phillips J, Chan DA, Zaki BI, Murnane JP, Petritsch C, Compton DA. Numerical chromosomal instability mediates susceptibility to radiation treatment. Nature Communications. 6: 5990. PMID 25606712 DOI: 10.1038/ncomms6990  1
2015 Godek KM, Kabeche L, Compton DA. Regulation of kinetochore-microtubule attachments through homeostatic control during mitosis. Nature Reviews. Molecular Cell Biology. 16: 57-64. PMID 25466864 DOI: 10.1038/nrm3916  1
2014 Bakhoum SF, Kabeche L, Murnane JP, Zaki BI, Compton DA. DNA-damage response during mitosis induces whole-chromosome missegregation. Cancer Discovery. 4: 1281-9. PMID 25107667 DOI: 10.1158/2159-8290.CD-14-0403  1
2014 Kleyman M, Kabeche L, Compton DA. STAG2 promotes error correction in mitosis by regulating kinetochore-microtubule attachments. Journal of Cell Science. 127: 4225-33. PMID 25074805 DOI: 10.1242/jcs.151613  1
2014 Bakhoum SF, Silkworth WT, Nardi IK, Nicholson JM, Compton DA, Cimini D. The mitotic origin of chromosomal instability. Current Biology : Cb. 24: R148-9. PMID 24556433 DOI: 10.1016/j.cub.2014.01.019  1
2013 Kabeche L, Compton DA. Cyclin A regulates kinetochore microtubules to promote faithful chromosome segregation. Nature. 502: 110-3. PMID 24013174 DOI: 10.1038/nature12507  1
2013 Orr B, Compton DA. A double-edged sword: how oncogenes and tumor suppressor genes can contribute to chromosomal instability. Frontiers in Oncology. 3: 164. PMID 23825799 DOI: 10.3389/fonc.2013.00164  1
2012 Maia AR, Garcia Z, Kabeche L, Barisic M, Maffini S, Macedo-Ribeiro S, Cheeseman IM, Compton DA, Kaverina I, Maiato H. Cdk1 and Plk1 mediate a CLASP2 phospho-switch that stabilizes kinetochore-microtubule attachments. The Journal of Cell Biology. 199: 285-301. PMID 23045552 DOI: 10.1083/jcb.201203091  1
2012 Hood EA, Kettenbach AN, Gerber SA, Compton DA. Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation. Molecular Biology of the Cell. 23: 2264-74. PMID 22535524 DOI: 10.1091/mbc.E11-12-1013  1
2012 Bakhoum SF, Compton DA. Chromosomal instability and cancer: a complex relationship with therapeutic potential. The Journal of Clinical Investigation. 122: 1138-43. PMID 22466654 DOI: 10.1172/JCI59954  1
2012 Kabeche L, Compton DA. Checkpoint-independent stabilization of kinetochore-microtubule attachments by Mad2 in human cells. Current Biology : Cb. 22: 638-44. PMID 22405866 DOI: 10.1016/j.cub.2012.02.030  1
2012 Bakhoum SF, Compton DA. Kinetochores and disease: keeping microtubule dynamics in check! Current Opinion in Cell Biology. 24: 64-70. PMID 22196931 DOI: 10.1016/j.ceb.2011.11.012  1
2011 Bakhoum SF, Danilova OV, Kaur P, Levy NB, Compton DA. Chromosomal instability substantiates poor prognosis in patients with diffuse large B-cell lymphoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 7704-11. PMID 22184286 DOI: 10.1158/1078-0432.CCR-11-2049  1
2011 Thompson SL, Compton DA. Chromosome missegregation in human cells arises through specific types of kinetochore-microtubule attachment errors. Proceedings of the National Academy of Sciences of the United States of America. 108: 17974-8. PMID 21997207 DOI: 10.1073/pnas.1109720108  1
2011 Charlebois BD, Kollu S, Schek HT, Compton DA, Hunt AJ. Spindle pole mechanics studied in mitotic asters: dynamic distribution of spindle forces through compliant linkages. Biophysical Journal. 100: 1756-64. PMID 21463589 DOI: 10.1016/j.bpj.2011.02.017  1
2011 Galimberti F, Thompson SL, Ravi S, Compton DA, Dmitrovsky E. Anaphase catastrophe is a target for cancer therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 1218-22. PMID 21288923 DOI: 10.1158/1078-0432.CCR-10-1178  1
2011 Thompson SL, Compton DA. Chromosomes and cancer cells. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 19: 433-44. PMID 21190130 DOI: 10.1007/s10577-010-9179-y  1
2011 Compton DA. Mechanisms of aneuploidy. Current Opinion in Cell Biology. 23: 109-13. PMID 20810265 DOI: 10.1016/j.ceb.2010.08.007  1
2010 Manning AL, Bakhoum SF, Maffini S, Correia-Melo C, Maiato H, Compton DA. CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity. The Embo Journal. 29: 3531-43. PMID 20852589 DOI: 10.1038/emboj.2010.230  1
2010 Thompson SL, Bakhoum SF, Compton DA. Mechanisms of chromosomal instability. Current Biology : Cb. 20: R285-95. PMID 20334839 DOI: 10.1016/j.cub.2010.01.034  1
2010 Thompson SL, Compton DA. Proliferation of aneuploid human cells is limited by a p53-dependent mechanism. The Journal of Cell Biology. 188: 369-81. PMID 20123995 DOI: 10.1083/jcb.200905057  1
2010 Galimberti F, Thompson SL, Liu X, Li H, Memoli V, Green SR, DiRenzo J, Greninger P, Sharma SV, Settleman J, Compton DA, Dmitrovsky E. Targeting the cyclin E-Cdk-2 complex represses lung cancer growth by triggering anaphase catastrophe. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 109-20. PMID 20028770 DOI: 10.1158/1078-0432.CCR-09-2151  1
2009 Kollu S, Bakhoum SF, Compton DA. Interplay of microtubule dynamics and sliding during bipolar spindle formation in mammalian cells. Current Biology : Cb. 19: 2108-13. PMID 19931454 DOI: 10.1016/j.cub.2009.10.056  1
2009 Bakhoum SF, Genovese G, Compton DA. Deviant kinetochore microtubule dynamics underlie chromosomal instability. Current Biology : Cb. 19: 1937-42. PMID 19879145 DOI: 10.1016/j.cub.2009.09.055  1
2009 Maffini S, Maia AR, Manning AL, Maliga Z, Pereira AL, Junqueira M, Shevchenko A, Hyman A, Yates JR, Galjart N, Compton DA, Maiato H. Motor-independent targeting of CLASPs to kinetochores by CENP-E promotes microtubule turnover and poleward flux. Current Biology : Cb. 19: 1566-72. PMID 19733075 DOI: 10.1016/j.cub.2009.07.059  1
2009 Bakhoum SF, Compton DA. Cancer: CINful centrosomes. Current Biology : Cb. 19: R642-5. PMID 19674544 DOI: 10.1016/j.cub.2009.06.039  1
2009 Bakhoum SF, Thompson SL, Manning AL, Compton DA. Genome stability is ensured by temporal control of kinetochore-microtubule dynamics. Nature Cell Biology. 11: 27-35. PMID 19060894 DOI: 10.1038/ncb1809  1
2008 Manning AL, Compton DA. SnapShot: Nonmotor proteins in spindle assembly. Cell. 134: 694. PMID 18724941 DOI: 10.1016/j.cell.2008.08.001  1
2008 Thompson SL, Compton DA. Examining the link between chromosomal instability and aneuploidy in human cells. The Journal of Cell Biology. 180: 665-72. PMID 18283116 DOI: 10.1083/jcb.200712029  1
2008 Manning AL, Compton DA. Structural and regulatory roles of nonmotor spindle proteins. Current Opinion in Cell Biology. 20: 101-6. PMID 18178073 DOI: 10.1016/j.ceb.2007.11.004  1
2007 Compton DA. Chromosome orientation. The Journal of Cell Biology. 179: 179-81. PMID 17954603 DOI: 10.1083/jcb.200709152  1
2007 Myers LC, Compton DA. Mitosis: springtime for chromatin. Current Biology : Cb. 17: R460-2. PMID 17580075 DOI: 10.1016/j.cub.2007.04.019  1
2007 Manning AL, Ganem NJ, Bakhoum SF, Wagenbach M, Wordeman L, Compton DA. The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells. Molecular Biology of the Cell. 18: 2970-9. PMID 17538014 DOI: 10.1091/mbc.E07-02-0110  1
2007 Manning AL, Compton DA. Mechanisms of spindle-pole organization are influenced by kinetochore activity in mammalian cells. Current Biology : Cb. 17: 260-5. PMID 17276919 DOI: 10.1016/j.cub.2006.11.071  1
2006 Compton DA. Mitosis: disorderly conduct at the kinetochore. Current Biology : Cb. 16: R494-6. PMID 16824907 DOI: 10.1016/j.cub.2006.06.010  1
2006 Compton DA. Chromosomes walk the line. Nature Cell Biology. 8: 308-10. PMID 16607267 DOI: 10.1038/ncb0406-308  1
2006 Ganem NJ, Compton DA. Functional roles of poleward microtubule flux during mitosis. Cell Cycle (Georgetown, Tex.). 5: 481-5. PMID 16552178  1
2005 Ganem NJ, Upton K, Compton DA. Efficient mitosis in human cells lacking poleward microtubule flux. Current Biology : Cb. 15: 1827-32. PMID 16243029 DOI: 10.1016/j.cub.2005.08.065  1
2005 Compton DA. Regulation of mitosis by poly(ADP-ribosyl)ation. The Biochemical Journal. 391: e5-6. PMID 16212557 DOI: 10.1042/BJ20051437  1
2005 Compton DA. Mitosis: PARty time in the spindle. Current Biology : Cb. 15: R178-9. PMID 15753032 DOI: 10.1016/j.cub.2005.02.047  1
2004 Kisurina-Evgenieva O, Mack G, Du Q, Macara I, Khodjakov A, Compton DA. Multiple mechanisms regulate NuMA dynamics at spindle poles. Journal of Cell Science. 117: 6391-400. PMID 15561764 DOI: 10.1242/jcs.01568  1
2004 Ganem NJ, Compton DA. The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK. The Journal of Cell Biology. 166: 473-8. PMID 15302853 DOI: 10.1083/jcb.200404012  1
2004 Einarson MB, Cukierman E, Compton DA, Golemis EA. Human enhancer of invasion-cluster, a coiled-coil protein required for passage through mitosis. Molecular and Cellular Biology. 24: 3957-71. PMID 15082789 DOI: 10.1128/MCB.24.9.3957-3971.2004  1
2004 Chakravarty A, Howard L, Compton DA. A mechanistic model for the organization of microtubule asters by motor and non-motor proteins in a mammalian mitotic extract. Molecular Biology of the Cell. 15: 2116-32. PMID 14978218 DOI: 10.1091/mbc.E03-08-0579  1
2003 Levesque AA, Howard L, Gordon MB, Compton DA. A functional relationship between NuMA and kid is involved in both spindle organization and chromosome alignment in vertebrate cells. Molecular Biology of the Cell. 14: 3541-52. PMID 12972545 DOI: 10.1091/mbc.E03-02-0082  1
2003 Khodjakov A, Copenagle L, Gordon MB, Compton DA, Kapoor TM. Minus-end capture of preformed kinetochore fibers contributes to spindle morphogenesis. The Journal of Cell Biology. 160: 671-83. PMID 12604591 DOI: 10.1083/jcb.200208143  1
2002 Garrett S, Auer K, Compton DA, Kapoor TM. hTPX2 is required for normal spindle morphology and centrosome integrity during vertebrate cell division. Current Biology : Cb. 12: 2055-9. PMID 12477396 DOI: 10.1016/S0960-9822(02)01277-0  1
2002 Du Q, Taylor L, Compton DA, Macara IG. LGN blocks the ability of NuMA to bind and stabilize microtubules. A mechanism for mitotic spindle assembly regulation. Current Biology : Cb. 12: 1928-33. PMID 12445386 DOI: 10.1016/S0960-9822(02)01298-8  1
2002 Compton DA. Chromosome segregation: pulling from the poles. Current Biology : Cb. 12: R651-3. PMID 12361583 DOI: 10.1016/S0960-9822(02)01158-2  1
2002 Kapoor TM, Compton DA. Searching for the middle ground: mechanisms of chromosome alignment during mitosis. The Journal of Cell Biology. 157: 551-6. PMID 12011106 DOI: 10.1083/jcb.200202073  1
2001 Mack GJ, Compton DA. Analysis of mitotic microtubule-associated proteins using mass spectrometry identifies astrin, a spindle-associated protein Proceedings of the National Academy of Sciences of the United States of America. 98: 14434-14439. PMID 11724960 DOI: 10.1073/pnas.261371298  1
2001 Levesque AA, Compton DA. The chromokinesin Kid is necessary for chromosome arm orientation and oscillation, but not congression, on mitotic spindles Journal of Cell Biology. 154: 1135-1146. PMID 11564754 DOI: 10.1083/jcb.200106093  1
2001 Compton DA. In vitro approaches for the study of molecular motors in aster formation Methods in Cell Biology. 225-239. PMID 11550471  1
2001 Gordon MB, Howard L, Compton DA. Chromosome movement in mitosis requires microtubule anchorage at spindle poles. The Journal of Cell Biology. 152: 425-34. PMID 11157972  1
2000 Compton DA. Spindle assembly in animal cells Annual Review of Biochemistry. 69: 95-114. PMID 10966454 DOI: 10.1146/annurev.biochem.69.1.95  1
2000 Mountain V, Compton DA. Dissecting the role of molecular motors in the mitotic spindle Anatomical Record. 261: 14-24. PMID 10700732 DOI: 10.1002/(SICI)1097-0185(20000215)261:1<14::AID-AR5>3.0.CO;2-E  1
1999 Ye K, Compton DA, Lai MM, Walensky LD, Snyder SH. Protein 4.1N binding to nuclear mitotic apparatus protein in PC12 cells mediates the antiproliferative actions of nerve growth factor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 10747-56. PMID 10594058  1
1999 Compton DA. New tools for the antimitotic toolbox Science. 286: 913-914. PMID 10577242 DOI: 10.1126/science.286.5441.913  1
1999 Mountain V, Simerly C, Howard L, Ando A, Schatten G, Compton DA. The kinesin-related protein, HSET, opposes the activity of Eg5 and cross-links microtubules in the mammalian mitotic spindle Journal of Cell Biology. 147: 351-365. PMID 10525540 DOI: 10.1083/jcb.147.2.351  1
1999 Quintyne NJ, Gill SR, Eckley DM, Crego CL, Compton DA, Schroer TA. Dynactin is required for microtubule anchoring at centrosomes. The Journal of Cell Biology. 147: 321-34. PMID 10525538 DOI: 10.1083/jcb.147.2.321  1
1999 Dionne MA, Howard L, Compton DA. NuMA is a component of an insoluble matrix at mitotic spindle poles Cell Motility and the Cytoskeleton. 42: 189-203. PMID 10098933 DOI: 10.1002/(SICI)1097-0169(1999)42:3<189::AID-CM3>3.0.CO;2-X  1
1998 Compton DA. [27] Production of M-phase and I-phase extracts from mammalian cells Methods in Enzymology. 298: 331-339. PMID 9751892 DOI: 10.1016/S0076-6879(98)98029-6  1
1998 Compton DA. Focusing on spindle poles Journal of Cell Science. 111: 1477-1481. PMID 9580556  1
1997 Gaglio T, Dionne MA, Compton DA. Mitotic spindle poles are organized by structural and motor proteins in addition to centrosomes Journal of Cell Biology. 138: 1055-1066. PMID 9281583 DOI: 10.1083/jcb.138.5.1055  1
1997 Saredi A, Howard L, Compton DA. Phosphorylation regulates the assembly of NuMA in a mammalian mitotic extract Journal of Cell Science. 110: 1287-1297. PMID 9202389  1
1996 Saredi A, Howard L, Compton DA. NuMA assembles into an extensive filamentous structure when expressed in the cell cytoplasm Journal of Cell Science. 109: 619-630. PMID 8907707  1
1996 Gaglio T, Saredi A, Bingham JB, Hasbani MJ, Gill SR, Schroer TA, Compton DA. Opposing motor activities are required for the organization of the mammalian mitotic spindle pole. The Journal of Cell Biology. 135: 399-414. PMID 8896597 DOI: 10.1083/jcb.135.2.399  1
1995 Compton DA, Luo C. Mutation of the predicted p34cdc2 phosphorylation sites in NuMA impair the assembly of the mitotic spindle and block mitosis Journal of Cell Science. 108: 621-633. PMID 7769006  1
1995 Gaglio T, Saredi A, Compton DA. NuMA is required for the organization of microtubules into aster-like mitotic arrays Journal of Cell Biology. 131: 693-708. PMID 7593190 DOI: 10.1083/jcb.131.3.693  1
1994 Ludérus MEE, Den Blaauwen JL, De Smit OJB, Compton DA, Van Driel R. Binding of matrix attachment regions to lamin polymers involves single-stranded regions and the minor groove Molecular and Cellular Biology. 14: 6297-6305. PMID 8065361  1
1994 Compton DA, Cleveland DW. NuMA, a nuclear protein involved in mitosis and nuclear reformation. Current Opinion in Cell Biology. 6: 343-6. PMID 7917323 DOI: 10.1016/0955-0674(94)90024-8  1
1993 Compton DA, Cleveland DW. NuMA is required for the proper completion of mitosis Journal of Cell Biology. 120: 947-957. PMID 8432734  1
1992 Compton DA, Szilak I, Cleveland DW. Primary structure of NuMA, an intranuclear protein that defines a novel pathway for segregation of proteins at mitosis Journal of Cell Biology. 116: 1395-1408. PMID 1541636  1
1991 Yen TJ, Compton DA, Wise D, Zinkowski RP, Brinkley BR, Earnshaw WC, Cleveland DW. CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase. The Embo Journal. 10: 1245-54. PMID 2022189  1
1991 Compton DA, Yen TJ, Cleveland DW. Identification of novel centromere/kinetochore-associated proteins using monoclonal antibodies generated against human mitotic chromosome scaffolds Journal of Cell Biology. 112: 1083-1097. PMID 1999466  1
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