Renate B. Pilz - Publications

Affiliations: 
Biomedical Sciences University of California, San Diego, La Jolla, CA 
Area:
Cell Biology, Biochemistry

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Year Citation  Score
2024 Kalyanaraman H, Casteel DE, China SP, Zhuang S, Boss GR, Pilz RB. A plasma membrane-associated form of the androgen receptor enhances nuclear androgen signaling in osteoblasts and prostate cancer cells. Science Signaling. 17: eadi7861. PMID 38289986 DOI: 10.1126/scisignal.adi7861  0.673
2023 Kalyanaraman H, Casteel DE, Cabriales JA, Tat J, Zhuang S, Chan A, Dretchen KL, Boss GR, Pilz RB. The Antioxidant/Nitric Oxide-Quenching Agent Cobinamide Prevents Aortic Disease in a Mouse Model of Marfan Syndrome. Jacc. Basic to Translational Science. 9: 46-62. PMID 38362350 DOI: 10.1016/j.jacbts.2023.07.014  0.651
2023 Hu T, Kalyanaraman H, Pilz RB, Casteel DE. Phosphatase regulatory subunit MYPT2 knock-out partially compensates for the cardiac dysfunction in mice caused by lack of myosin light chain kinase 3. The Journal of Biological Chemistry. 104584. PMID 36889588 DOI: 10.1016/j.jbc.2023.104584  0.65
2022 Kalyanaraman H, Pal China S, Cabriales JA, Moininazeri J, Casteel DE, Garcia JJ, Wong VW, Chen A, Sah RL, Boss GR, Pilz RB. Protein Kinase G2 Is Essential for Skeletal Homeostasis and Adaptation to Mechanical Loading in Male but not Female Mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 36371651 DOI: 10.1002/jbmr.4746  0.653
2022 Chang S, Tat J, China SP, Kalyanaraman H, Zhuang S, Chan A, Lai C, Radic Z, Abdel-Rahman EA, Casteel DE, Pilz RB, Ali SS, Boss GR. Cobinamide is a strong and versatile antioxidant that overcomes oxidative stress in cells, flies, and diabetic mice. Pnas Nexus. 1: pgac191. PMID 36276587 DOI: 10.1093/pnasnexus/pgac191  0.633
2022 Aminzai S, Hu T, Pilz RB, Casteel DE. PKGIα is activated by metal-dependent oxidation in vitro but not in intact cells. The Journal of Biological Chemistry. 298: 102175. PMID 35752367 DOI: 10.1016/j.jbc.2022.102175  0.696
2021 Schwaerzer GK, Casteel DE, Cividini F, Kalyanaraman H, Zhuang S, Gu Y, Dalton ND, Peterson KL, Dillmann WH, Boss GR, Pilz RB. Constitutive Protein Kinase G Activation Exacerbates Stress-induced Cardiomyopathy. British Journal of Pharmacology. PMID 34000062 DOI: 10.1111/bph.15530  0.654
2020 Wahwah N, Dhar D, Chen H, Zhuang S, Chan A, Casteel DE, Kalyanaraman H, Pilz RB, Boss GR. Metabolic interaction between amino acid deprivation and cisplatin synergistically reduces phosphoribosyl-pyrophosphate and augments cisplatin cytotoxicity. Scientific Reports. 10: 19907. PMID 33199755 DOI: 10.1038/s41598-020-76958-7  0.618
2020 Chan MH, Aminzai S, Hu T, Taran A, Li S, Kim C, Pilz RB, Casteel DE. A substitution in cGMP-dependent protein kinase 1 associated with aortic disease induces an active conformation in the absence of cGMP. The Journal of Biological Chemistry. PMID 32506052 DOI: 10.1074/Jbc.Ra119.010984  0.723
2020 Schall N, Garcia JJ, Kalyanaraman H, Pal China S, Lee JJ, Sah RL, Pfeifer A, Pilz RB. Protein Kinase G1 regulates bone regeneration and rescues diabetic fracture healing. Jci Insight. PMID 32315291 DOI: 10.1172/Jci.Insight.135355  0.363
2019 Schwaerzer GK, Kalyanaraman H, Casteel DE, Dalton ND, Gu Y, Lee S, Zhuang S, Wahwah N, Schilling JM, Patel HH, Zhang Q, Makino A, Milewicz DM, Peterson KL, Boss GR, ... Pilz RB, et al. Aortic pathology from protein kinase G activation is prevented by an antioxidant vitamin B analog. Nature Communications. 10: 3533. PMID 31387997 DOI: 10.1038/S41467-019-11389-1  0.683
2018 Ramdani G, Schall N, Kalyanaraman H, Wahwah N, Moheize S, Lee JJ, Sah RL, Pfeifer A, Casteel DE, Pilz RB. cGMP-dependent protein kinase-2 regulates bone mass and prevents diabetic bone loss. The Journal of Endocrinology. PMID 29914933 DOI: 10.1530/Joe-18-0286  0.695
2018 Kalyanaraman H, Schall N, Pilz RB. Nitric oxide and cyclic GMP functions in bone. Nitric Oxide : Biology and Chemistry. PMID 29550520 DOI: 10.1016/J.Niox.2018.03.007  0.436
2018 Kalyanaraman H, Schwaerzer G, Ramdani G, Castillo F, Scott BT, Dillmann W, Sah RL, Casteel DE, Pilz RB. Potein Kinase G Activation Reverses Oxidative Stress and Restores Osteoblast Function and Bone Formation in Male Mice With Type 1 Diabetes. Diabetes. PMID 29301852 DOI: 10.2337/Db17-0965  0.7
2017 Todd Milne G, Sandner P, Lincoln KA, Harrison PC, Chen H, Wang H, Clifford H, Qian HS, Wong D, Sarko C, Fryer R, Richman J, Reinhart GA, Boustany CM, Pullen SS, ... ... Pilz R, et al. Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017. Bmc Pharmacology & Toxicology. 18: 64. PMID 29035170 DOI: 10.1186/s40360-017-0170-5  0.58
2017 Kalyanaraman H, Zhuang S, Pilz RB, Casteel DE. The Activity of cGMP-dependent Protein Kinase Iα is not Directly Regulated by Oxidation-induced Disulfide Formation at Cysteine 43. The Journal of Biological Chemistry. PMID 28360102 DOI: 10.1074/Jbc.C117.787358  0.74
2016 Kalyanaraman H, Ramdani G, Joshua J, Schall N, Boss GR, Cory E, Sah RL, Casteel DE, Pilz RB. A Novel, Direct No Donor Regulates Osteoblast and Osteoclast Functions and Increases Bone Mass in Ovariectomized Mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 27391172 DOI: 10.1002/Jbmr.2909  0.684
2016 Jiang J, Chan A, Ali S, Saha A, Haushalter KJ, Lam WM, Glasheen M, Parker J, Brenner M, Mahon SB, Patel HH, Ambasudhan R, Lipton SA, Pilz RB, Boss GR. Hydrogen Sulfide-Mechanisms of Toxicity and Development of an Antidote. Scientific Reports. 6: 20831. PMID 26877209 DOI: 10.1038/Srep20831  0.308
2015 Kalyanaraman H, Joshua J, Zhuang S, Corey E, Sah R, Pilz RB. NO/GMP as mediators of estrogen effects in bone Bmc Pharmacology and Toxicology. 16. DOI: 10.1186/2050-6511-16-S1-A10  0.387
2014 Joshua J, Kalyanaraman H, Marathe N, Pilz RB. Nitric oxide as a mediator of estrogen effects in osteocytes. Vitamins and Hormones. 96: 247-63. PMID 25189390 DOI: 10.1016/B978-0-12-800254-4.00010-6  0.797
2014 Joshua J, Schwaerzer GK, Kalyanaraman H, Cory E, Sah RL, Li M, Vaida F, Boss GR, Pilz RB. Soluble guanylate cyclase as a novel treatment target for osteoporosis. Endocrinology. 155: 4720-30. PMID 25188528 DOI: 10.1210/En.2014-1343  0.443
2014 Saha A, Connelly S, Jiang J, Zhuang S, Amador DT, Phan T, Pilz RB, Boss GR. Akt phosphorylation and regulation of transketolase is a nodal point for amino acid control of purine synthesis. Molecular Cell. 55: 264-76. PMID 24981175 DOI: 10.1016/J.Molcel.2014.05.028  0.436
2014 Kalyanaraman H, Schwappacher R, Joshua J, Zhuang S, Scott BT, Klos M, Casteel DE, Frangos JA, Dillmann W, Boss GR, Pilz RB. Nongenomic thyroid hormone signaling occurs through a plasma membrane-localized receptor. Science Signaling. 7: ra48. PMID 24847117 DOI: 10.1126/Scisignal.2004911  0.719
2014 Pilz RB, VanHook AM. Science Signaling Podcast: 20 May 2014 Science Signaling. 7: pc13-pc13. DOI: 10.1126/Scisignal.2005451  0.314
2013 Spitler R, Schwappacher R, Wu T, Kong X, Yokomori K, Pilz RB, Boss GR, Berns MW. Nitrosyl-cobinamide (NO-Cbi), a new nitric oxide donor, improves wound healing through cGMP/cGMP-dependent protein kinase. Cellular Signalling. 25: 2374-82. PMID 23920342 DOI: 10.1016/J.Cellsig.2013.07.029  0.408
2013 Fridman A, Saha A, Chan A, Casteel DE, Pilz RB, Boss GR. Cell cycle regulation of purine synthesis by phosphoribosyl pyrophosphate and inorganic phosphate. The Biochemical Journal. 454: 91-9. PMID 23734909 DOI: 10.1042/Bj20130153  0.681
2013 Schwappacher R, Kilic A, Kojonazarov B, Lang M, Diep T, Zhuang S, Gawlowski T, Schermuly RT, Pfeifer A, Boss GR, Pilz RB. A molecular mechanism for therapeutic effects of cGMP-elevating agents in pulmonary arterial hypertension. The Journal of Biological Chemistry. 288: 16557-66. PMID 23612967 DOI: 10.1074/Jbc.M113.458729  0.382
2012 Casteel DE, Turner S, Schwappacher R, Rangaswami H, Su-Yuo J, Zhuang S, Boss GR, Pilz RB. Rho isoform-specific interaction with IQGAP1 promotes breast cancer cell proliferation and migration. The Journal of Biological Chemistry. 287: 38367-78. PMID 22992742 DOI: 10.1074/Jbc.M112.377499  0.694
2012 Rangaswami H, Schwappacher R, Tran T, Chan GC, Zhuang S, Boss GR, Pilz RB. Protein kinase G and focal adhesion kinase converge on Src/Akt/β-catenin signaling module in osteoblast mechanotransduction. The Journal of Biological Chemistry. 287: 21509-19. PMID 22563076 DOI: 10.1074/Jbc.M112.347245  0.54
2012 Marathe N, Rangaswami H, Zhuang S, Boss GR, Pilz RB. Pro-survival effects of 17β-estradiol on osteocytes are mediated by nitric oxide/cGMP via differential actions of cGMP-dependent protein kinases I and II. The Journal of Biological Chemistry. 287: 978-88. PMID 22117068 DOI: 10.1074/Jbc.M111.294959  0.803
2011 Rangaswami H, Schwappacher R, Marathe N, Casteel DE, Haas B, Pfeifer A, Shattil S, Boss G, Pilz RB. Src activation by cGMP/PKG II in osteoblasts: characterization of a mechano-sensitive signalling complex Bmc Pharmacology. 11. DOI: 10.1186/1471-2210-11-S1-O24  0.745
2010 Rangaswami H, Schwappacher R, Marathe N, Zhuang S, Casteel DE, Haas B, Chen Y, Pfeifer A, Kato H, Shattil S, Boss GR, Pilz RB. Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts. Science Signaling. 3: ra91. PMID 21177494 DOI: 10.1126/Scisignal.2001423  0.797
2010 Casteel DE, Smith-Nguyen EV, Sankaran B, Roh SH, Pilz RB, Kim C. A crystal structure of the cyclic GMP-dependent protein kinase I{beta} dimerization/docking domain reveals molecular details of isoform-specific anchoring. The Journal of Biological Chemistry. 285: 32684-8. PMID 20826808 DOI: 10.1074/Jbc.C110.161430  0.708
2009 Rangaswami H, Marathe N, Zhuang S, Chen Y, Yeh JC, Frangos JA, Boss GR, Pilz RB. Type II cGMP-dependent protein kinase mediates osteoblast mechanotransduction. The Journal of Biological Chemistry. 284: 14796-808. PMID 19282289 DOI: 10.1074/Jbc.M806486200  0.802
2009 Casteel DE, Zhuang S, Zeng Y, Perrino FW, Boss GR, Goulian M, Pilz RB. A DNA polymerase-α·primase cofactor with homology to replication protein A-32 regulates DNA replication in mammalian cells Journal of Biological Chemistry. 284: 5807-5818. PMID 19119139 DOI: 10.1074/Jbc.M807593200  0.649
2009 Wang W, Fridman A, Blackledge W, Connely S, Wilson IA, Pilz R, Boss GR. The phosphatidylinositol 3-kinase/Akt cassette regulates purine nucleotide synthesis Journal of Biological Chemistry. 284: 3521-3528. PMID 19068483 DOI: 10.1074/Jbc.M806707200  0.449
2009 Zhang T, Schwappacher R, Zhuang S, Pilz RB. Regulation of smooth muscle-specific gene expression by cGMP-dependent protein kinase Bmc Pharmacology. 9: P79. DOI: 10.1186/1471-2210-9-S1-P79  0.395
2009 Casteel DE, Smith-Nguyen EV, Sankaran B, Spraggon G, Hampton EN, Pilz RB, Taylor SS, Kim C. The first crystal structure of cyclic GMP-dependent protein kinase Iβ dimerization/docking domain reveals molecular details of isoform-specific anchoring Bmc Pharmacology. 9: P6. DOI: 10.1186/1471-2210-9-S1-P6  0.675
2008 Casteel DE, Zhang T, Zhuang S, Pilz RB. cGMP-dependent protein kinase anchoring by IRAG regulates its nuclear translocation and transcriptional activity. Cellular Signalling. 20: 1392-9. PMID 18450420 DOI: 10.1016/J.Cellsig.2008.03.009  0.741
2008 Turner SJ, Zhuang S, Zhang T, Boss GR, Pilz RB. Effects of lovastatin on Rho isoform expression, activity, and association with guanine nucleotide dissociation inhibitors. Biochemical Pharmacology. 75: 405-13. PMID 17920041 DOI: 10.1016/J.Bcp.2007.08.031  0.445
2007 Broderick KE, Alvarez L, Balasubramanian M, Belke DD, Makino A, Chan A, Woods VL, Dillmann WH, Sharma VS, Pilz RB, Bigby TD, Boss GR. Nitrosyl-cobinamide, a new and direct nitric oxide releasing drug effective in vivo. Experimental Biology and Medicine (Maywood, N.J.). 232: 1432-40. PMID 18040067 DOI: 10.3181/0703-Rm-70  0.328
2007 Zhang T, Zhuang S, Casteel DE, Looney DJ, Boss GR, Pilz RB. A cysteine-rich LIM-only protein mediates regulation of smooth muscle-specific gene expression by cGMP-dependent protein kinase. The Journal of Biological Chemistry. 282: 33367-80. PMID 17878170 DOI: 10.1074/Jbc.M707186200  0.714
2007 Broderick KE, Zhang T, Rangaswami H, Zeng Y, Zhao X, Boss GR, Pilz RB. Guanosine 3',5'-cyclic monophosphate (cGMP)/cGMP-dependent protein kinase induce interleukin-6 transcription in osteoblasts. Molecular Endocrinology (Baltimore, Md.). 21: 1148-62. PMID 17341596 DOI: 10.1210/Me.2005-0389  0.415
2006 Broderick KE, Potluri P, Zhuang S, Scheffler IE, Sharma VS, Pilz RB, Boss GR. Cyanide detoxification by the cobalamin precursor cobinamide. Experimental Biology and Medicine (Maywood, N.J.). 231: 641-9. PMID 16636313 DOI: 10.1177/153537020623100519  0.3
2006 Zeng Y, Zhuang S, Gloddek J, Tseng CC, Boss GR, Pilz RB. Regulation of cGMP-dependent protein kinase expression by Rho and Kruppel-like transcription factor-4. The Journal of Biological Chemistry. 281: 16951-61. PMID 16632465 DOI: 10.1074/Jbc.M602099200  0.475
2005 Casteel DE, Boss GR, Pilz RB. Identification of the interface between cGMP-dependent protein kinase Ibeta and its interaction partners TFII-I and IRAG reveals a common interaction motif. The Journal of Biological Chemistry. 280: 38211-8. PMID 16166082 DOI: 10.1074/Jbc.M507021200  0.675
2005 Zhao X, Zhuang S, Chen Y, Boss GR, Pilz RB. Cyclic GMP-dependent protein kinase regulates CCAAT enhancer-binding protein beta functions through inhibition of glycogen synthase kinase-3. The Journal of Biological Chemistry. 280: 32683-92. PMID 16055922 DOI: 10.1074/Jbc.M505486200  0.448
2005 Pilz RB, Broderick KE. Role of cyclic GMP in gene regulation. Frontiers in Bioscience : a Journal and Virtual Library. 10: 1239-68. PMID 15769622 DOI: 10.2741/1616  0.438
2005 Kambo A, Sharma VS, Casteel DE, Woods VL, Pilz RB, Boss GR. Nitric oxide inhibits mammalian methylmalonyl-CoA mutase. The Journal of Biological Chemistry. 280: 10073-82. PMID 15647267 DOI: 10.1074/Jbc.M411842200  0.657
2005 Broderick KE, Singh V, Zhuang S, Kambo A, Chen JC, Sharma VS, Pilz RB, Boss GR. Nitric oxide scavenging by the cobalamin precursor cobinamide. The Journal of Biological Chemistry. 280: 8678-85. PMID 15632180 DOI: 10.1074/Jbc.M410498200  0.427
2004 Zhuang S, Nguyen GT, Chen Y, Gudi T, Eigenthaler M, Jarchau T, Walter U, Boss GR, Pilz RB. Vasodilator-stimulated phosphoprotein activation of serum-response element-dependent transcription occurs downstream of RhoA and is inhibited by cGMP-dependent protein kinase phosphorylation. The Journal of Biological Chemistry. 279: 10397-407. PMID 14679200 DOI: 10.1074/Jbc.M313048200  0.477
2003 Pilz RB, Casteel DE. Regulation of gene expression by cyclic GMP. Circulation Research. 93: 1034-46. PMID 14645134 DOI: 10.1161/01.Res.0000103311.52853.48  0.723
2003 Chen Y, Zhuang S, Cassenaer S, Casteel DE, Gudi T, Boss GR, Pilz RB. Synergism between calcium and cyclic GMP in cyclic AMP response element-dependent transcriptional regulation requires cooperation between CREB and C/EBP-beta. Molecular and Cellular Biology. 23: 4066-82. PMID 12773552 DOI: 10.1128/Mcb.23.12.4066-4082.2003  0.679
2003 Chen JC, Zhuang S, Nguyen TH, Boss GR, Pilz RB. Oncogenic Ras leads to Rho activation by activating the mitogen-activated protein kinase pathway and decreasing Rho-GTPase-activating protein activity. The Journal of Biological Chemistry. 278: 2807-18. PMID 12429740 DOI: 10.1074/Jbc.M207943200  0.364
2002 Im E, von Lintig FC, Chen J, Zhuang S, Qui W, Chowdhury S, Worley PF, Boss GR, Pilz RB. Rheb is in a high activation state and inhibits B-Raf kinase in mammalian cells. Oncogene. 21: 6356-65. PMID 12214276 DOI: 10.1038/Sj.Onc.1205792  0.372
2002 Gudi T, Chen JC, Casteel DE, Seasholtz TM, Boss GR, Pilz RB. cGMP-dependent protein kinase inhibits serum-response element-dependent transcription by inhibiting rho activation and functions. The Journal of Biological Chemistry. 277: 37382-93. PMID 12119292 DOI: 10.1074/Jbc.M204491200  0.741
2002 Casteel DE, Zhuang S, Gudi T, Tang J, Vuica M, Desiderio S, Pilz RB. cGMP-dependent protein kinase Iβ physically and functionally interacts with the transcriptional regulator TFII-I Journal of Biological Chemistry. 277: 32003-32014. PMID 12082086 DOI: 10.1074/Jbc.M112332200  0.706
2001 Dahle MK, Knutsen HK, Taskén KA, Pilz R, Taskén K. Cyclic AMP regulates expression of the RIα subunit of cAMP‐dependent protein kinase through an alternatively spliced 5′ UTR Febs Journal. 268: 5920-5929. PMID 11722580 DOI: 10.1046/J.0014-2956.2001.02542.X  0.328
2000 Gudi T, Casteel DE, Vinson C, Boss GR, Pilz RB. NO activation of fos promoter elements requires nuclear translocation of G-kinase I and CREB phosphorylation but is independent of MAP kinase activation. Oncogene. 19: 6324-33. PMID 11175347 DOI: 10.1038/Sj.Onc.1204007  0.74
2000 Von Lintig FC, Pilz RB, Boss GR. Quantitative determination of Rap 1 activation in cyclic nucleotide-treated HL-60 leukemic cells: Lack of Rap 1 activation in variant cells Oncogene. 19: 4029-4034. PMID 10962559 DOI: 10.1038/Sj.Onc.1203741  0.453
2000 Qiu W, Zhuang S, Von Lintig FC, Boss GR, Pilz RB. Cell type-specific regulation of B-Raf kinase by cAMP and 14-3-3 proteins Journal of Biological Chemistry. 275: 31921-31929. PMID 10931830 DOI: 10.1074/Jbc.M003327200  0.479
1999 Suhasini M, Pilz RB. Transcriptional elongation of c-myb is regulated by NF-κB (p50/RelB) Oncogene. 18: 7360-7369. PMID 10602492 DOI: 10.1038/Sj.Onc.1203158  0.342
1999 Gudi T, Hong GK, Vaandrager AB, Lohmann SM, Pilz RB. Nitric oxide and cGMP regulate gene expression in neuronal and glial cells by activating type II cGMP-dependent protein kinase. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 13: 2143-52. PMID 10593861 DOI: 10.1096/Fasebj.13.15.2143  0.485
1999 Idriss SD, Gudi T, Casteel DE, Kharitonov VG, Pilz RB, Boss GR. Nitric oxide regulation of gene transcription via soluble guanylate cyclase and type I cGMP-dependent protein kinase. The Journal of Biological Chemistry. 274: 9489-93. PMID 10092632 DOI: 10.1074/Jbc.274.14.9489  0.754
1999 Eigenthaler M, Lohmann SM, Walter U, Pilz RB. Signal transduction by cGMP-dependent protein kinases and their emerging roles in the regulation of cell adhesion and gene expression. Reviews of Physiology, Biochemistry and Pharmacology. 135: 173-209. PMID 9932484 DOI: 10.1007/Bfb0033673  0.458
1998 Suhasini M, Li H, Lohmann SM, Boss GR, Pilz RB. Cyclic-GMP-dependent protein kinase inhibits the Ras/Mitogen-activated protein kinase pathway. Molecular and Cellular Biology. 18: 6983-94. PMID 9819386 DOI: 10.1128/Mcb.18.12.6983  0.478
1998 Scheele JS, Pilz RB, Clark G, Gupta N, Loo D, Martis P, Boss GR. Decreased phosphorylation of a low molecular weight protein by cGMP-dependent protein kinase in variant HL-60 cells resistant to nitric oxide- and cGMP-induced differentiation Molecular and Cellular Biochemistry. 185: 111-121. PMID 9746217 DOI: 10.1023/A:1006834324419  0.478
1998 Casteel D, Suhasini M, Gudi T, Naima R, Pilz RB. Regulation of the erythroid transcription factor NF-E2 by cyclic adenosine monophosphate-dependent protein kinase Blood. 91: 3193-3201. PMID 9558374 DOI: 10.1182/Blood.V91.9.3193  0.721
1997 Suhasini M, Reddy CD, Reddy EP, DiDonato JA, Pilz RB. cAMP-induced NF-kappaB (p50/relB) binding to a c-myb intronic enhancer correlates with c-myb up-regulation and inhibition of erythroleukemia cell differentiation. Oncogene. 15: 1859-70. PMID 9362453 DOI: 10.1038/Sj.Onc.1201530  0.366
1997 Gudi T, Lohmann SM, Pilz RB. Regulation of gene expression by cyclic GMP-dependent protein kinase requires nuclear translocation of the kinase: identification of a nuclear localization signal. Molecular and Cellular Biology. 17: 5244-54. PMID 9271402 DOI: 10.1128/Mcb.17.9.5244  0.49
1997 Talwar N, Pilz RB, Yu Z, Burlingame A, Boss GR. A low molecular weight substance purified from human placenta inhibits cAMP-dependent protein kinase and activates protein kinase C Molecular and Cellular Biochemistry. 170: 75-83. PMID 9144320 DOI: 10.1023/A:1006836826926  0.427
1996 Gudi T, Huvar I, Meinecke M, Lohmann SM, Boss GR, Pilz RB. Regulation of gene expression by cGMP-dependent protein kinase. Transactivation of the c-fos promoter. The Journal of Biological Chemistry. 271: 4597-600. PMID 8617718 DOI: 10.1074/Jbc.271.9.4597  0.483
1995 Pilz RB, Suhasini M, Idriss S, Meinkoth JL, Boss GR. Nitric oxide and cGMP analogs activate transcription from AP-1-responsive promoters in mammalian cells Faseb Journal. 9: 552-558. PMID 7737465 DOI: 10.1096/Fasebj.9.7.7737465  0.444
1995 Garingo AD, Suhasini M, Andrews NC, Pilz RB. cAMP-dependent protein kinase is necessary for increased NF-E2·DNA complex formation during erythroleukemia cell differentiation Journal of Biological Chemistry. 270: 9169-9177. PMID 7721832 DOI: 10.1074/Jbc.270.16.9169  0.47
1994 Scheele JS, Pilz RB, Quilliam LA, Boss GR. Identification of a ras-related protein in murine erythroleukemia cells that is a cAMP-dependent protein kinase substrate and is phosphorylated during chemically induced differentiation Journal of Biological Chemistry. 269: 18599-18606. PMID 8034608  0.327
1993 Pilz RB. Impaired erythroid-specific gene expression in cAMP-dependent protein kinase-deficient murine erythroleukemia cells Journal of Biological Chemistry. 268: 20252-20258. PMID 8376386  0.377
1992 Pilz RB, Eigenthaler M, Boss GR. Chemically induced murine erythroleukemia cell differentiation is severely impaired when cAMP-dependent protein kinase activity is repressed by transfected genes Journal of Biological Chemistry. 267: 16161-16167. PMID 1644803  0.329
1987 Pilz RB, Van Den Berghe G, Boss GR. Adenosine dialdehyde and nitrous oxide induce HL-60 differentiation Blood. 70: 1161-1164. PMID 3651602 DOI: 10.1182/Blood.V70.4.1161.1161  0.334
1987 Pilz RB, Van Den Berghe G, Boss GR. Induction of HL-60 differentiation by starvation for a single essential amino acid but not by protein synthesis inhibitors Journal of Clinical Investigation. 79: 1006-1009. PMID 3469216 DOI: 10.1172/Jci112867  0.327
1984 Boss GR, Pilz RB. Decreased methionine synthesis in purine nucleoside-treated T and B lymphoblasts and reversal by homocysteine Journal of Clinical Investigation. 74: 1262-1268. PMID 6332827 DOI: 10.1172/Jci111536  0.3
Low-probability matches (unlikely to be authored by this person)
1998 Scheele JS, Pilz RB, Von Lintig FC, Boss GR. Deficient post-translational processing of Rap 1A in variant HL-60 cells Oncogene. 17: 2211-2223. PMID 9811452 DOI: 10.1038/Sj.Onc.1202137  0.299
1984 Pilz RB, Willis RC, Wanlass S, Seegmiller JE. Regulation of human lymphoblast ecto-5'-nucleotidase by zinc. Advances in Experimental Medicine and Biology. 165: 147-52. PMID 6326497 DOI: 10.1007/978-1-4757-0390-0_29  0.291
2009 Rangaswami H, Zhuang N, Chen Y, Pilz RB. Role of PKG II in osteoblast mechanotransduction Bmc Pharmacology. 9: S32. DOI: 10.1186/1471-2210-9-S1-S32  0.288
1995 Kharitonov VG, Sharma VS, Pilz RB, Magde D, Koesling D. Basis of guanylate cyclase activation by carbon monoxide Proceedings of the National Academy of Sciences of the United States of America. 92: 2568-2571. PMID 7708686 DOI: 10.1073/Pnas.92.7.2568  0.28
2005 Zeng Y, Pilz RB. Regulation of PKG expression in vascular smooth muscle cells Bmc Pharmacology. 5: S16. DOI: 10.1186/1471-2210-5-S1-S16  0.276
2003 Sharma VS, Pilz RB, Boss GR, Magde D. Reactions of nitric oxide with vitamin B12 and its precursor, cobinamide. Biochemistry. 42: 8900-8. PMID 12873151 DOI: 10.1021/Bi034469T  0.275
2006 Broderick KE, Feala J, McCulloch A, Paternostro G, Sharma VS, Pilz RB, Boss GR. The nitric oxide scavenger cobinamide profoundly improves survival in a Drosophila melanogaster model of bacterial sepsis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1865-73. PMID 16940158 DOI: 10.1096/Fj.06-5780Com  0.268
2011 Schwappacher R, Diep T, Boss G, Pilz R. cGMP and PKGI are required for vascular BMP signaling Bmc Pharmacology. 11. DOI: 10.1186/1471-2210-11-S1-P65  0.263
2013 Kalyanaraman H, Schwappacher R, Joshua J, Zhuang S, Scott B, Dillmann W, Frangos J, Pilz RB. Non-genomic thyroid hormone signaling through NO/cGMP/PKGII Bmc Pharmacology and Toxicology. 14. DOI: 10.1186/2050-6511-14-S1-O26  0.258
2007 Broderick KE, Balasubramanian M, Chan A, Potluri P, Feala J, Belke DD, McCulloch A, Sharma VS, Pilz RB, Bigby TD, Boss GR. The cobalamin precursor cobinamide detoxifies nitroprusside-generated cyanide Experimental Biology and Medicine. 232: 789-798. PMID 17526771 DOI: 10.3181/00379727-232-2320789  0.255
1995 Suhasini M, Boss GR, Pascual FE, Pilz RB. Nitric oxide-releasing agents and cGMP analogues inhibit murine erythroleukemia cell differentiation and suppress erythroid-specific gene expression: correlation with decreased DNA binding of NF-E2 and altered c-myb mRNA expression. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 6: 1559-66. PMID 9019161  0.253
1986 Pilz RB, Boss GR. The synthesis of phosphoribosylpyrophosphate from glucose decreases during amino acid starvation of human lymphoblasts Advances in Experimental Medicine and Biology. 195: 611-614. PMID 2429513 DOI: 10.1007/978-1-4684-1248-2_95  0.253
1992 Idriss SD, Pilz RB, Sharma VS, Boss GR. Studies on cytosolic guanylate cyclase from human placenta Biochemical and Biophysical Research Communications. 183: 312-320. PMID 1347448 DOI: 10.1016/0006-291X(92)91645-7  0.243
1994 Pilz RB, Berjis M, Idriss SD, Scheele JS, Suhasini M, Gaol L, Scheffler IE, Boss GR. Isolation and characterization of HL-60 cells resistant to nitroprusside- induced differentiation Journal of Biological Chemistry. 269: 32155-32161. PMID 7798212  0.239
2014 Yan M, Dong Z, Zhao F, Chauncey T, Deauna-Limayo D, Wang-Rodriguez J, Liu D, Wang HY, Pilz R. CD20-positive plasmablastic lymphoma with excellent response to bortezomib combined with rituximab. European Journal of Haematology. 93: 77-80. PMID 24528507 DOI: 10.1111/Ejh.12286  0.233
2015 Chan A, Jiang J, Fridman A, Guo LT, Shelton GD, Liu MT, Green C, Haushalter KJ, Patel HH, Lee J, Yoon D, Burney T, Mukai D, Mahon SB, Brenner M, ... Pilz RB, et al. Nitrocobinamide, a new cyanide antidote that can be administered by intramuscular injection. Journal of Medicinal Chemistry. 58: 1750-9. PMID 25650735 DOI: 10.1021/Jm501565K  0.227
2010 Blackledge WC, Blackledge CW, Griesel A, Mahon SB, Brenner M, Pilz RB, Boss GR. New facile method to measure cyanide in blood. Analytical Chemistry. 82: 4216-21. PMID 20420400 DOI: 10.1021/Ac100519Z  0.214
1990 Grens A, Steglich C, Pilz R, Scheffler IE. Nucleotide sequence of the Chinese hamster ornithine decarboxylase gene. Nucleic Acids Research. 17: 10497. PMID 2602162 DOI: 10.1093/Nar/17.24.10497  0.212
2023 Tat J, Chang SC, Link CD, Razo-Lopez S, Ingerto MJ, Katebian B, Chan A, Kalyanaraman H, Pilz RB, Boss GR. The vitamin B analog cobinamide ameliorates azide toxicity in cells, , and mice. Clinical Toxicology (Philadelphia, Pa.). 1-11. PMID 37010385 DOI: 10.1080/15563650.2023.2185125  0.197
2008 Broderick KE, Chan A, Balasubramanian M, Feala J, Reed SL, Panda M, Sharma VS, Pilz RB, Bigby TD, Boss GR. Cyanide produced by human isolates of Pseudomonas aeruginosa contributes to lethality in Drosophila melanogaster. The Journal of Infectious Diseases. 197: 457-64. PMID 18199034 DOI: 10.1086/525282  0.196
2016 Bebarta VS, Brittain M, Chan A, Garrett N, Yoon D, Burney T, Mukai D, Babin M, Pilz RB, Mahon SB, Brenner M, Boss GR. Sodium Nitrite and Sodium Thiosulfate Are Effective Against Acute Cyanide Poisoning When Administered by Intramuscular Injection. Annals of Emergency Medicine. PMID 28041825 DOI: 10.1016/J.Annemergmed.2016.09.034  0.194
2011 Chan A, Crankshaw DL, Monteil A, Patterson SE, Nagasawa HT, Briggs JE, Kozocas JA, Mahon SB, Brenner M, Pilz RB, Bigby TD, Boss GR. The combination of cobinamide and sulfanegen is highly effective in mouse models of cyanide poisoning. Clinical Toxicology (Philadelphia, Pa.). 49: 366-73. PMID 21740135 DOI: 10.3109/15563650.2011.584879  0.191
1997 Pilz RB, Huvar I, Scheele JS, Van den Berghe G, Boss GR. A decrease in the intracellular guanosine 5'-triphosphate concentration is necessary for granulocytic differentiation of HL-60 cells, but growth cessation and differentiation are not associated with a change in the activation state of ras, the transforming principle of HL-60 cells Cell Growth and Differentiation. 8: 53-59. PMID 8993834  0.186
1990 Pilz RB, Steglich C, Scheffler IE. Molecular and genetic characterization of an ornithine decarboxylase-deficient Chinese hamster cell line Journal of Biological Chemistry. 265: 8880-8886. PMID 1692838  0.176
1984 Pilz RB, Willis RC, Boss GR. The influence of ribose 5-phosphate availability on purine synthesis of cultured human lymphoblasts and mitogen-stimulated lymphocytes. The Journal of Biological Chemistry. 259: 2927-35. PMID 6699001  0.151
2021 Chan A, Lee J, Bhadra S, Bortey-Sam N, Hendry-Hofer TB, Bebarta VS, Mahon SB, Brenner M, Logue B, Pilz RB, Boss GR. Development of sodium tetrathionate as a cyanide and methanethiol antidote. Clinical Toxicology (Philadelphia, Pa.). 1-10. PMID 34328378 DOI: 10.1080/15563650.2021.1953517  0.074
1982 Pilz RB, Willis RC, Seegmiller JE. Regulation of human lymphoblast plasma membrane 5'-nucleotidase by zinc. The Journal of Biological Chemistry. 257: 13544-9. PMID 6292194  0.073
1985 Boss GR, Pilz RB. Phosphoribosylpyrophosphate synthesis from glucose decreases during amino acid starvation of human lymphoblasts Federation Proceedings. 44.  0.044
2021 Tat J, Heskett K, Satomi S, Pilz RB, Golomb BA, Boss GR. Sodium azide poisoning: a narrative review. Clinical Toxicology (Philadelphia, Pa.). 1-15. PMID 34128439 DOI: 10.1080/15563650.2021.1906888  0.038
2020 Tat J, Hays B, Teachworth M, Kuo A, Pilz RB, Golomb BA, Boss GR. Assessment of High School Students' Participation in Blood Donation and Registration as an Organ Donor. Jama Network Open. 3: e2016377. PMID 32945872 DOI: 10.1001/jamanetworkopen.2020.16377  0.01
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