Dean P. Edwards - Publications

University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Molecular Biology, Biochemistry

126 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.


Year Citation  Score
2020 Asavasupreechar T, Saito R, Miki Y, Edwards DP, Boonyaratanakornkit V, Sasano H. Systemic distribution of progesterone receptor subtypes in human tissues. The Journal of Steroid Biochemistry and Molecular Biology. 105599. PMID 31991170 DOI: 10.1016/j.jsbmb.2020.105599  0.44
2019 Asavasupreechar T, Saito R, Edwards DP, Sasano H, Boonyaratanakornkit V. Progesterone Receptor Isoform B Expression in Pulmonary Neuroendocrine Cells Decreases Cell Proliferation. The Journal of Steroid Biochemistry and Molecular Biology. PMID 30926428 DOI: 10.1016/j.jsbmb.2019.03.022  0.44
2017 Acharya KD, Nettles SA, Sellers KJ, Im DD, Harling M, Pattanayak C, Vardar-Ulu D, Lichti CF, Huang S, Edwards DP, Srivastava DP, Denner L, Tetel MJ. The Progestin Receptor Interactome in the Female Mouse Hypothalamus: Interactions with Synaptic Proteins Are Isoform Specific and Ligand Dependent. Eneuro. 4. PMID 28955722 DOI: 10.1523/ENEURO.0272-17.2017  0.32
2016 Kim JA, Tan Y, Wang X, Cao X, Veeraraghavan J, Liang Y, Edwards DP, Huang S, Pan X, Li K, Schiff R, Wang XS. Comprehensive functional analysis of the tousled-like kinase 2 frequently amplified in aggressive luminal breast cancers. Nature Communications. 7: 12991. PMID 27694828 DOI: 10.1038/ncomms12991  0.68
2016 Grimm SL, Hartig SM, Edwards DP. Progesterone Receptor Signaling Mechanisms. Journal of Molecular Biology. PMID 27380738 DOI: 10.1016/j.jmb.2016.06.020  0.68
2016 Welte T, Kim IS, Tian L, Gao X, Wang H, Li J, Holdman XB, Herschkowitz JI, Pond A, Xie G, Kurley S, Nguyen T, Liao L, Dobrolecki LE, Pang L, ... ... Edwards DP, et al. Erratum: Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation. Nature Cell Biology. 18: 822. PMID 27350446 DOI: 10.1038/ncb3379  0.32
2016 Kaushik AK, Shojaie A, Panzitt K, Sonavane R, Venghatakrishnan H, Manikkam M, Zaslavsky A, Putluri V, Vasu VT, Zhang Y, Khan AS, Lloyd S, Szafran AT, Dasgupta S, Bader DA, ... ... Edwards DP, et al. Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer. Nature Communications. 7: 11612. PMID 27194471 DOI: 10.1038/ncomms11612  0.68
2016 Welte T, Kim IS, Tian L, Gao X, Wang H, Li J, Holdman XB, Herschkowitz JI, Pond A, Xie G, Kurley S, Nguyen T, Liao L, Dobrolecki LE, Pang L, ... ... Edwards DP, et al. Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation. Nature Cell Biology. PMID 27183469 DOI: 10.1038/ncb3355  0.68
2015 Holdman XB, Welte T, Rajapakshe K, Pond A, Coarfa C, Mo Q, Huang S, Hilsenbeck SG, Edwards DP, Zhang X, Rosen JM. Upregulation of EGFR signaling is correlated with tumor stroma remodeling and tumor recurrence in FGFR1-driven breast cancer. Breast Cancer Research : Bcr. 17: 141. PMID 26581390 DOI: 10.1186/s13058-015-0649-1  0.68
2015 Chang CH, Zhang M, Rajapakshe K, Coarfa C, Edwards D, Huang S, Rosen JM. Mammary Stem Cells and Tumor-Initiating Cells Are More Resistant to Apoptosis and Exhibit Increased DNA Repair Activity in Response to DNA Damage. Stem Cell Reports. PMID 26300228 DOI: 10.1016/j.stemcr.2015.07.009  0.32
2014 Karlin KL, Mondal G, Hartman JK, Tyagi S, Kurley SJ, Bland CS, Hsu TY, Renwick A, Fang JE, Migliaccio I, Callaway C, Nair A, Dominguez-Vidana R, Nguyen DX, Osborne CK, ... ... Edwards DP, et al. The oncogenic STP axis promotes triple-negative breast cancer via degradation of the REST tumor suppressor. Cell Reports. 9: 1318-32. PMID 25453754 DOI: 10.1016/j.celrep.2014.10.011  0.32
2014 Grimm SL, Ward RD, Obr AE, Franco HL, Fernandez-Valdivia R, Kim JS, Roberts JM, Jeong JW, DeMayo FJ, Lydon JP, Edwards DP, Weigel NL. A role for site-specific phosphorylation of mouse progesterone receptor at serine 191 in vivo. Molecular Endocrinology (Baltimore, Md.). 28: 2025-37. PMID 25333515 DOI: 10.1210/me.2014-1206  0.68
2014 Moore NL, Edwards DP, Weigel NL. Cyclin A2 and its associated kinase activity are required for optimal induction of progesterone receptor target genes in breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 144: 471-82. PMID 25220500 DOI: 10.1016/j.jsbmb.2014.09.009  0.68
2014 Veeraraghavan J, Tan Y, Cao XX, Kim JA, Wang X, Chamness GC, Maiti SN, Cooper LJ, Edwards DP, Contreras A, Hilsenbeck SG, Chang EC, Schiff R, Wang XS. Recurrent ESR1-CCDC170 rearrangements in an aggressive subset of oestrogen receptor-positive breast cancers. Nature Communications. 5: 4577. PMID 25099679 DOI: 10.1038/ncomms5577  0.68
2014 Goswami D, Callaway C, Pascal BD, Kumar R, Edwards DP, Griffin PR. Influence of domain interactions on conformational mobility of the progesterone receptor detected by hydrogen/deuterium exchange mass spectrometry. Structure (London, England : 1993). 22: 961-73. PMID 24909783 DOI: 10.1016/j.str.2014.04.013  0.68
2014 Pathiraja TN, Nayak SR, Xi Y, Jiang S, Garee JP, Edwards DP, Lee AV, Chen J, Shea MJ, Santen RJ, Gannon F, Kangaspeska S, Jelinek J, Issa JP, Richer JK, et al. Epigenetic reprogramming of HOXC10 in endocrine-resistant breast cancer. Science Translational Medicine. 6: 229ra41. PMID 24670685 DOI: 10.1126/scitranslmed.3008326  0.68
2014 Simons SS, Edwards DP, Kumar R. Minireview: dynamic structures of nuclear hormone receptors: new promises and challenges. Molecular Endocrinology (Baltimore, Md.). 28: 173-82. PMID 24284822 DOI: 10.1210/me.2013-1334  0.68
2013 Obr AE, Grimm SL, Bishop KA, Pike JW, Lydon JP, Edwards DP. Progesterone receptor and Stat5 signaling cross talk through RANKL in mammary epithelial cells. Molecular Endocrinology (Baltimore, Md.). 27: 1808-24. PMID 24014651 DOI: 10.1210/me.2013-1077  0.68
2013 Kumar R, Moure CM, Khan SH, Callaway C, Grimm SL, Goswami D, Griffin PR, Edwards DP. Regulation of the structurally dynamic N-terminal domain of progesterone receptor by protein-induced folding. The Journal of Biological Chemistry. 288: 30285-99. PMID 23995840 DOI: 10.1074/jbc.M113.491787  0.68
2013 McDonough PM, Maciejewski-Lenoir D, Hartig SM, Hanna RA, Whittaker R, Heisel A, Nicoll JB, Buehrer BM, Christensen K, Mancini MG, Mancini MA, Edwards DP, Price JH. Differential phosphorylation of perilipin 1A at the initiation of lipolysis revealed by novel monoclonal antibodies and high content analysis. Plos One. 8: e55511. PMID 23405163 DOI: 10.1371/journal.pone.0055511  0.68
2012 Smith CL, Migliaccio I, Chaubal V, Wu MF, Pace MC, Hartmaier R, Jiang S, Edwards DP, Gutiérrez MC, Hilsenbeck SG, Oesterreich S. Elevated nuclear expression of the SMRT corepressor in breast cancer is associated with earlier tumor recurrence. Breast Cancer Research and Treatment. 136: 253-65. PMID 23015261 DOI: 10.1007/s10549-012-2262-7  0.68
2012 Obr AE, Edwards DP. The biology of progesterone receptor in the normal mammary gland and in breast cancer. Molecular and Cellular Endocrinology. 357: 4-17. PMID 22193050 DOI: 10.1016/j.mce.2011.10.030  0.68
2012 Hill KK, Roemer SC, Churchill ME, Edwards DP. Structural and functional analysis of domains of the progesterone receptor. Molecular and Cellular Endocrinology. 348: 418-29. PMID 21803119 DOI: 10.1016/j.mce.2011.07.017  0.68
2011 Buser AC, Obr AE, Kabotyanski EB, Grimm SL, Rosen JM, Edwards DP. Progesterone receptor directly inhibits β-casein gene transcription in mammary epithelial cells through promoting promoter and enhancer repressive chromatin modifications. Molecular Endocrinology (Baltimore, Md.). 25: 955-68. PMID 21527503 DOI: 10.1210/me.2011-0064  0.68
2011 Ferris MM, Stepp PC, Ranno KA, Mahmoud W, Ibbitson E, Jarvis J, Cox MM, Christensen K, Votaw H, Edwards DP, Rowlen KL. Evaluation of the Virus Counter® for rapid baculovirus quantitation. Journal of Virological Methods. 171: 111-6. PMID 20970458 DOI: 10.1016/j.jviromet.2010.10.010  0.68
2010 Greger JG, Fursov N, Cooch N, McLarney S, Freedman LP, Edwards DP, Cheskis BJ. Phosphorylation of MNAR promotes estrogen activation of phosphatidylinositol 3-kinase (Molecular and Cellular Biology (2007) 27, 5, (1904-1913)) Molecular and Cellular Biology. 30: 1568. PMID 20194629 DOI: 10.1128/MCB.00090-10  0.68
2010 Wardell SE, Narayanan R, Weigel NL, Edwards DP. Partial agonist activity of the progesterone receptor antagonist RU486 mediated by an amino-terminal domain coactivator and phosphorylation of serine400. Molecular Endocrinology (Baltimore, Md.). 24: 335-45. PMID 20008003 DOI: 10.1210/me.2008-0081  0.68
2009 Holley AK, Kiningham KK, Spitz DR, Edwards DP, Jenkins JT, Moore MR. Progestin stimulation of manganese superoxide dismutase and invasive properties in T47D human breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 117: 23-30. PMID 19563893 DOI: 10.1016/j.jsbmb.2009.06.004  0.68
2009 Hill KK, Roemer SC, Jones DN, Churchill ME, Edwards DP. A progesterone receptor co-activator (JDP2) mediates activity through interaction with residues in the carboxyl-terminal extension of the DNA binding domain. The Journal of Biological Chemistry. 284: 24415-24. PMID 19553667 DOI: 10.1074/jbc.M109.003244  0.68
2009 Lydon JP, Edwards DP. Finally! A model for progesterone receptor action in normal human breast. Endocrinology. 150: 2988-90. PMID 19549883 DOI: 10.1210/en.2009-0383  0.68
2009 Kabotyanski EB, Rijnkels M, Freeman-Zadrowski C, Buser AC, Edwards DP, Rosen JM. Lactogenic hormonal induction of long distance interactions between beta-casein gene regulatory elements. The Journal of Biological Chemistry. 284: 22815-24. PMID 19542223 DOI: 10.1074/jbc.M109.032490  0.68
2008 Fernandez-Valdivia R, Mukherjee A, Creighton CJ, Buser AC, DeMayo FJ, Edwards DP, Lydon JP. Transcriptional response of the murine mammary gland to acute progesterone exposure. Endocrinology. 149: 6236-50. PMID 18687774 DOI: 10.1210/en.2008-0768  0.68
2008 Roemer SC, Adelman J, Churchill ME, Edwards DP. Mechanism of high-mobility group protein B enhancement of progesterone receptor sequence-specific DNA binding. Nucleic Acids Research. 36: 3655-66. PMID 18474528 DOI: 10.1093/nar/gkn249  0.68
2008 Boonyaratanakornkit V, Bi Y, Rudd M, Edwards DP. The role and mechanism of progesterone receptor activation of extra-nuclear signaling pathways in regulating gene transcription and cell cycle progression. Steroids. 73: 922-8. PMID 18321550 DOI: 10.1016/j.steroids.2008.01.010  0.68
2007 McGowan EM, Russell AJ, Boonyaratanakornkit V, Saunders DN, Lehrbach GM, Sergio CM, Musgrove EA, Edwards DP, Sutherland RL. Progestins reinitiate cell cycle progression in antiestrogen-arrested breast cancer cells through the B-isoform of progesterone receptor. Cancer Research. 67: 8942-51. PMID 17875737 DOI: 10.1158/0008-5472.CAN-07-1255  0.68
2007 Boonyaratanakornkit V, Edwards DP. Receptor mechanisms mediating non-genomic actions of sex steroids. Seminars in Reproductive Medicine. 25: 139-53. PMID 17447204 DOI: 10.1055/s-2007-973427  0.68
2007 Carnevale RP, Proietti CJ, Salatino M, Urtreger A, Peluffo G, Edwards DP, Boonyaratanakornkit V, Charreau EH, Bal de Kier Joffé E, Schillaci R, Elizalde PV. Progestin effects on breast cancer cell proliferation, proteases activation, and in vivo development of metastatic phenotype all depend on progesterone receptor capacity to activate cytoplasmic signaling pathways. Molecular Endocrinology (Baltimore, Md.). 21: 1335-58. PMID 17440047 DOI: 10.1210/me.2006-0304  0.44
2007 Greger JG, Fursov N, Cooch N, McLarney S, Freedman LP, Edwards DP, Cheskis BJ. Phosphorylation of MNAR promotes estrogen activation of phosphatidylinositol 3-kinase. Molecular and Cellular Biology. 27: 1904-13. PMID 17194752 DOI: 10.1128/MCB.01732-06  0.68
2007 Boonyaratanakornkit V, McGowan E, Sherman L, Mancini MA, Cheskis BJ, Edwards DP. The role of extranuclear signaling actions of progesterone receptor in mediating progesterone regulation of gene expression and the cell cycle. Molecular Endocrinology (Baltimore, Md.). 21: 359-75. PMID 17138644 DOI: 10.1210/me.2006-0337  0.68
2007 Buser AC, Gass-Handel EK, Wyszomierski SL, Doppler W, Leonhardt SA, Schaack J, Rosen JM, Watkin H, Anderson SM, Edwards DP. Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells. Molecular Endocrinology (Baltimore, Md.). 21: 106-25. PMID 16973758 DOI: 10.1210/me.2006-0297  0.68
2006 Roemer SC, Donham DC, Sherman L, Pon VH, Edwards DP, Churchill ME. Structure of the progesterone receptor-deoxyribonucleic acid complex: novel interactions required for binding to half-site response elements. Molecular Endocrinology (Baltimore, Md.). 20: 3042-52. PMID 16931575 DOI: 10.1210/me.2005-0511  0.68
2006 Brayman MJ, Julian J, Mulac-Jericevic B, Conneely OM, Edwards DP, Carson DD. Progesterone receptor isoforms A and B differentially regulate MUC1 expression in uterine epithelial cells. Molecular Endocrinology (Baltimore, Md.). 20: 2278-91. PMID 16740655 DOI: 10.1210/me.2005-0343  0.68
2005 Wardell SE, Kwok SC, Sherman L, Hodges RS, Edwards DP. Regulation of the amino-terminal transcription activation domain of progesterone receptor by a cofactor-induced protein folding mechanism. Molecular and Cellular Biology. 25: 8792-808. PMID 16199860 DOI: 10.1128/MCB.25.20.8792-8808.2005  0.68
2005 Narayanan R, Edwards DP, Weigel NL. Human progesterone receptor displays cell cycle-dependent changes in transcriptional activity. Molecular and Cellular Biology. 25: 2885-98. PMID 15798179 DOI: 10.1128/MCB.25.8.2885-2898.2005  0.68
2005 Wardell SE, Edwards DP. Mechanisms controlling agonist and antagonist potential of selective progesterone receptor modulators (SPRMs). Seminars in Reproductive Medicine. 23: 9-21. PMID 15714386 DOI: 10.1055/s-2005-864030  0.68
2005 Edwards DP. Regulation of signal transduction pathways by estrogen and progesterone. Annual Review of Physiology. 67: 335-76. PMID 15709962 DOI: 10.1146/annurev.physiol.67.040403.120151  0.68
2005 Narayanan R, Adigun AA, Edwards DP, Weigel NL. Cyclin-dependent kinase activity is required for progesterone receptor function: novel role for cyclin A/Cdk2 as a progesterone receptor coactivator. Molecular and Cellular Biology. 25: 264-77. PMID 15601848 DOI: 10.1128/MCB.25.1.264-277.2005  0.68
2004 Boonyaratanakornkit V, Edwards DP. Receptor mechanisms of rapid extranuclear signalling initiated by steroid hormones. Essays in Biochemistry. 40: 105-20. PMID 15242342  0.68
2004 Melvin VS, Harrell C, Adelman JS, Kraus WL, Churchill M, Edwards DP. The role of the C-terminal extension (CTE) of the estrogen receptor alpha and beta DNA binding domain in DNA binding and interaction with HMGB. The Journal of Biological Chemistry. 279: 14763-71. PMID 14739282 DOI: 10.1074/jbc.M313335200  0.68
2003 Edwards DP, Boonyaratanakornkit V. Rapid extranuclear signaling by the estrogen receptor (ER): MNAR couples ER and Src to the MAP kinase signaling pathway. Molecular Interventions. 3: 12-5. PMID 14993433 DOI: 10.1124/mi.3.1.12  0.68
2003 Leonhardt SA, Boonyaratanakornkit V, Edwards DP. Progesterone receptor transcription and non-transcription signaling mechanisms. Steroids. 68: 761-70. PMID 14667966 DOI: 10.1016/S0039-128X(03)00129-6  0.68
2002 Edwards DP, Wardell SE, Boonyaratanakornkit V. Progesterone receptor interacting coregulatory proteins and cross talk with cell signaling pathways. The Journal of Steroid Biochemistry and Molecular Biology. 83: 173-86. PMID 12650714 DOI: 10.1016/S0960-0760(02)00265-0  0.68
2002 Leonhardt SA, Edwards DP. Mechanism of action of progesterone antagonists. Experimental Biology and Medicine (Maywood, N.J.). 227: 969-80. PMID 12486206  0.68
2002 Press M, Spaulding B, Groshen S, Kaminsky D, Hagerty M, Sherman L, Christensen K, Edwards DP. Comparison of different antibodies for detection of progesterone receptor in breast cancer. Steroids. 67: 799-813. PMID 12123792 DOI: 10.1016/S0039-128X(02)00039-9  0.68
2002 Wardell SE, Boonyaratanakornkit V, Adelman JS, Aronheim A, Edwards DP. Jun dimerization protein 2 functions as a progesterone receptor N-terminal domain coactivator. Molecular and Cellular Biology. 22: 5451-66. PMID 12101239 DOI: 10.1128/MCB.22.15.5451-5466.2002  0.68
2002 Melvin VS, Roemer SC, Churchill ME, Edwards DP. The C-terminal extension (CTE) of the nuclear hormone receptor DNA binding domain determines interactions and functional response to the HMGB-1/-2 co-regulatory proteins. The Journal of Biological Chemistry. 277: 25115-24. PMID 12006575 DOI: 10.1074/jbc.M110400200  0.68
2002 Schultz JR, Loven MA, Melvin VM, Edwards DP, Nardulli AM. Differential modulation of DNA conformation by estrogen receptors alpha and beta. The Journal of Biological Chemistry. 277: 8702-7. PMID 11773069 DOI: 10.1074/jbc.M108491200  0.68
2001 Melvin VS, Edwards DP. Expression and purification of recombinant human progesterone receptor in baculovirus and bacterial systems Methods in Molecular Biology (Clifton, N.J.). 176: 39-54. PMID 11554337  0.68
2001 Boonyaratanakornkit V, Scott MP, Ribon V, Sherman L, Anderson SM, Maller JL, Miller WT, Edwards DP. Progesterone receptor contains a proline-rich motif that directly interacts with SH3 domains and activates c-Src family tyrosine kinases. Molecular Cell. 8: 269-80. PMID 11545730 DOI: 10.1016/S1097-2765(01)00304-5  0.44
2001 Knotts TA, Orkiszewski RS, Cook RG, Edwards DP, Weigel NL. Identification of a phosphorylation site in the hinge region of the human progesterone receptor and additional amino-terminal phosphorylation sites. The Journal of Biological Chemistry. 276: 8475-83. PMID 11110801 DOI: 10.1074/jbc.M009805200  0.68
2000 Edwards DP. The role of coactivators and corepressors in the biology and mechanism of action of steroid hormone receptors Journal of Mammary Gland Biology and Neoplasia. 5: 307-324. PMID 14973393 DOI: 10.1023/A:1009503029176  0.68
2000 Giangrande PH, Kimbrel EA, Edwards DP, McDonnell DP. The opposing transcriptional activities of the two isoforms of the human progesterone receptor are due to differential cofactor binding. Molecular and Cellular Biology. 20: 3102-15. PMID 10757795 DOI: 10.1128/MCB.20.9.3102-3115.2000  0.68
2000 Edwards DP, Leonhardt SA, Gass-Handel E. Novel mechanisms of progesterone antagonists and progesterone receptor Journal of the Society For Gynecologic Investigation. 7. PMID 10732325  0.68
2000 Clemm DL, Sherman L, Boonyaratanakornkit V, Schrader WT, Weigel NL, Edwards DP. Differential hormone-dependent phosphorylation of progesterone receptor A and B forms revealed by a phosphoserine site-specific monoclonal antibody. Molecular Endocrinology (Baltimore, Md.). 14: 52-65. PMID 10628747 DOI: 10.1210/mend.14.1.0413  0.44
1999 Nazareth LV, Stenoien DL, Bingman WE, James AJ, Wu C, Zhang Y, Edwards DP, Mancini M, Marcelli M, Lamb DJ, Weigel NL. A C619Y mutation in the human androgen receptor causes inactivation and mislocalization of the receptor with concomitant sequestration of SRC-1 (steroid receptor coactivator 1) Molecular Endocrinology. 13: 2065-2075. PMID 10598582 DOI: 10.1210/mend.13.12.0382  0.68
1999 O'Conner JL, Wade MF, Edwards DP, Mahesh VB. Progesterone and regulation of the follicle-stimulating hormone (FSH-beta) gene. Steroids. 64: 592-7. PMID 10503714 DOI: 10.1016/S0039-128X(99)00038-0  0.68
1999 Melvin VS, Edwards DP. Coregulatory proteins in steroid hormone receptor action: The role of chromatin high mobility group proteins HMG-1 and -2 Steroids. 64: 576-586. PMID 10503712 DOI: 10.1016/S0039-128X(99)00036-7  0.68
1999 Tetel MJ, Giangrande PH, Leonhardt SA, McDonnell DP, Edwards DP. Hormone-dependent interaction between the amino- and carboxyl-terminal domains of progesterone receptor in vitro and in vivo. Molecular Endocrinology (Baltimore, Md.). 13: 910-24. PMID 10379890 DOI: 10.1210/mend.13.6.0300  0.68
1998 Leonhardt SA, Altmann M, Edwards DP. Agonist and antagonists induce homodimerization and mixed ligand heterodimerization of human progesterone receptors in vivo by a mammalian two-hybrid assay Molecular Endocrinology. 12: 1914-1930. PMID 9849965  0.68
1998 Romine LE, Wood JR, Lamia LA, Prendergast P, Edwards DP, Nardulli AM. The high mobility group protein 1 enhances binding of the estrogen receptor DNA binding domain to the estrogen response element Molecular Endocrinology. 12: 664-674. PMID 9605929  0.68
1998 Gass EK, Leonhardt SA, Nordeen SK, Edwards DP. The antagonists RU486 and ZK98299 stimulate progesterone receptor binding to deoxyribonucleic acid in vitro and in vivo, but have distinct effects on receptor conformation Endocrinology. 139: 1905-1919. PMID 9528977  0.68
1998 Edwards DP. Coregulatory Proteins in Nuclear Hormone Receptor Action Vitamins and Hormones. 55: 165-218. DOI: 10.1016/S0083-6729(08)60936-X  0.68
1997 O'Conner JL, Wade MF, Prendergast P, Edwards DP, Boonyaratanakornkit V, Mahesh VB. A 361 base pair region of the rat FSH-beta promoter contains multiple progesterone receptor-binding sequences and confers progesterone responsiveness. Molecular and Cellular Endocrinology. 136: 67-78. PMID 9510069 DOI: 10.1016/S0303-7207(97)00216-5  0.68
1997 Tetel MJ, Jung S, Carbajo P, Ladtkow T, Skafar DF, Edwards DP. Hinge and amino-terminal sequences contribute to solution dimerization of human progesterone receptor. Molecular Endocrinology (Baltimore, Md.). 11: 1114-28. PMID 9212059 DOI: 10.1210/mend.11.8.9963  0.68
1997 Zhang Y, Beck CA, Poletti A, Clement JP, Prendergast P, Yip TT, Hutchens TW, Edwards DP, Weigel NL. Phosphorylation of human progesterone receptor by cyclin-dependent kinase 2 on three sites that are authentic basal phosphorylation sites in vivo. Molecular Endocrinology (Baltimore, Md.). 11: 823-32. PMID 9171245 DOI: 10.1210/mend.11.6.0006  0.68
1996 Sabeur K, Edwards DP, Meizel S. Human sperm plasma membrane progesterone receptor(s) and the acrosome reaction Biology of Reproduction. 54: 993-1001. PMID 8722618 DOI: 10.1095/biolreprod54.5.993  0.68
1996 Prendergast P, Pan Z, Edwards DP. Progesterone receptor-induced bending of its target DNA: Distinct effects of the A and B receptor forms Molecular Endocrinology. 10: 393-407. PMID 8721984 DOI: 10.1210/mend.10.4.8721984  0.68
1996 Beck CA, Zhang Y, Altmann M, Weigel NL, Edwards DP. Stoichiometry and site-specific phosphorylation of human progesterone receptor in native target cells and in the baculovirus expression system. The Journal of Biological Chemistry. 271: 19546-55. PMID 8702648 DOI: 10.1074/jbc.271.32.19546  0.68
1996 Carbajo P, Christensen K, Edwards DP, Skafar DF. Binding of [3H]progesterone to the human progesterone receptor: Differences between individual and mixed isoforms Endocrinology. 137: 2339-2346. PMID 8641184 DOI: 10.1210/endo.137.6.8641184  0.68
1996 Beck CA, Zhang Y, Weigel NL, Edwards DP. Two types of anti-progestins have distinct effects on site-specific phosphorylation of human progesterone receptor. The Journal of Biological Chemistry. 271: 1209-17. PMID 8557652 DOI: 10.1074/jbc.271.2.1209  0.68
1995 Webster JC, Pedersen NR, Edwards DP, Beck CA, Miller WL. The 5'-flanking region of the ovine follicle-stimulating hormone-beta gene contains six progesterone response elements: three proximal elements are sufficient to increase transcription in the presence of progesterone. Endocrinology. 136: 1049-58. PMID 7867558 DOI: 10.1210/endo.136.3.7867558  0.68
1995 Nordeen SK, Bona BJ, Beck CA, Edwards DP, Borror KC, DeFranco DB. The two faces of a steroid antagonist: when an antagonist isn't. Steroids. 60: 97-104. PMID 7792825 DOI: 10.1016/0039-128X(94)00001-S  0.68
1995 Edwards DP, Altmann M, DeMarzo A, Zhang Y, Weigel NL, Beck CA. Progesterone receptor and the mechanism of action of progesterone antagonists. The Journal of Steroid Biochemistry and Molecular Biology. 53: 449-58. PMID 7626494 DOI: 10.1016/0960-0760(95)00091-D  0.68
1995 Zhang Y, Beck CA, Poletti A, Edwards DP, Weigel NL. Identification of a group of Ser-Pro motif hormone-inducible phosphorylation sites in the human progesterone receptor. Molecular Endocrinology (Baltimore, Md.). 9: 1029-40. PMID 7476977 DOI: 10.1210/mend.9.8.7476977  0.68
1994 Prendergast P, Oñate SA, Christense K, Edwards DP. Nuclear accessory factors enhance the binding of progesterone receptor to specific target DNA Journal of Steroid Biochemistry and Molecular Biology. 48: 1-13. PMID 8136295 DOI: 10.1016/0960-0760(94)90245-3  0.68
1993 Beck CA, Weigel NL, Moyer ML, Nordeen SK, Edwards DP. The progesterone antagonist RU486 acquires agonist activity upon stimulation of cAMP signaling pathways Proceedings of the National Academy of Sciences of the United States of America. 90: 4441-4445. PMID 8389450 DOI: 10.1073/pnas.90.10.4441  0.68
1993 Lieberman BA, Bona BJ, Edwards DP, Nordeen SK. The constitution of a progesterone response element Molecular Endocrinology. 7: 515-527. PMID 8388996 DOI: 10.1210/me.7.4.515  0.68
1993 Beck CA, Estes PA, Bona BJ, Muro-Cacho CA, Nordeen SK, Edwards DP. The steroid antagonist RU486 exerts different effects on the glucocorticoid and progesterone receptors. Endocrinology. 133: 728-40. PMID 8344212 DOI: 10.1210/endo.133.2.8344212  0.68
1993 Edwards DP, Weigel NL, Nordeen SK, Beck CA. Modulators of cellular protein phosphorylation alter the trans-activation function of human progesterone receptor and the biological activity of progesterone antagonists Breast Cancer Research and Treatment. 27: 41-56. PMID 8260729 DOI: 10.1007/BF00683192  0.68
1992 Weigel NL, Beck CA, Estes PA, Prendergast P, Altmann M, Christensen K, Edwards DP. Ligands induce conformational changes in the carboxyl-terminus of progesterone receptors which are detected by a site-directed antipeptide monoclonal antibody. Molecular Endocrinology (Baltimore, Md.). 6: 1585-97. PMID 1448113 DOI: 10.1210/mend.6.10.1448113  0.68
1992 Demarzo AM, Oñate SA, Nordeen SK, Edwards DP. Effects of the steroid antagonist RU486 on dimerization of the human progesterone receptor Biochemistry. 31: 10491-10501. PMID 1420166  0.68
1992 Beck CA, Edwards DP. Progesterone receptors in breast cancer Cancer Treatment and Research. 61: 317-352. PMID 1360240  0.68
1992 Beck CA, Weigel NL, Edwards DP. Effects of hormone and cellular modulators of protein phosphorylation on transcriptional activity, DNA binding, and phosphorylation of human progesterone receptors Molecular Endocrinology. 6: 607-620. PMID 1316549 DOI: 10.1210/me.6.4.607  0.68
1992 Edwards DP, Estes PA, Fadok VA, Bona BJ, Oñate S, Nordeen SK, Welch WJ. Heat shock alters the composition of heteromeric steroid receptor complexes and enhances receptor activity in vivo. Biochemistry. 31: 2482-91. PMID 1312348 DOI: 10.1021/bi00124a007  0.68
1991 Demarzo AM, Beck CA, Oñate SA, Edwards DP. Dimerization of mammalian progesterone receptors occurs in the absence of DNA and is related to the release of the 90-kDa heat shock protein Proceedings of the National Academy of Sciences of the United States of America. 88: 72-76. PMID 1986383  0.68
1991 Oñate SA, Estes PA, Welch WJ, Nordeen SK, Edwards DP. Evidence that heat shock protein-70 associated with progesterone receptors is not involved in receptor-DNA binding. Molecular Endocrinology (Baltimore, Md.). 5: 1993-2004. PMID 1791844 DOI: 10.1210/mend-5-12-1993  0.68
1991 Christensen K, Estes PA, Oñate SA, Beck CA, DeMarzo A, Altmann M, Lieberman BA, St John J, Nordeen SK, Edwards DP. Characterization and functional properties of the A and B forms of human progesterone receptors synthesized in a baculovirus system. Molecular Endocrinology (Baltimore, Md.). 5: 1755-70. PMID 1779977 DOI: 10.1210/mend-5-11-1755  0.68
1991 Edwards DP, DeMarzo AM, Oñate SA, Beck CA, Estes PA, Nordeen SK. Mechanisms controlling steroid receptor binding to specific DNA sequences. Steroids. 56: 271-8. PMID 1652169 DOI: 10.1016/0039-128X(91)90046-X  0.68
1989 El-Ashry D, Onate SA, Nordeen SK, Edwards DP. Human progesterone receptor complexed with the antagonist RU 486 binds to hormone response elements in a structurally altered form Molecular Endocrinology. 3: 1545-1558. PMID 2608048  0.68
1989 Kuhnel B, El-Ashry D, Edwards DP, Nordeen SK. Mapping contacts between unpurified human progesterone receptor and the hormone response element of mouse mammary tumor virus Dna. 8: 703-713. PMID 2558865  0.68
1989 Edwards DP, Kühnel B, Estes PA, Nordeen SK. Human progesterone receptor binding to mouse mammary tumor virus deoxyribonucleic acid: dependence on hormone and nonreceptor nuclear factor(s). Molecular Endocrinology (Baltimore, Md.). 3: 381-91. PMID 2540430 DOI: 10.1210/mend-3-2-381  0.68
1988 Elashry-Stowers D, Zava DT, Speers WC, Edwards DP. Immunocytochemical Localization of Progesterone Receptors in Breast Cancer with Anti-Human Receptor Monoclonal Antibodies Cancer Research. 48: 6462-6474. PMID 3180062  0.68
1988 Krett NL, Edwards DP, Horwitz KB. Chapter 14 Progesterone action and receptors New Comprehensive Biochemistry. 18: 241-267. DOI: 10.1016/S0167-7306(08)60649-3  0.68
1987 Estes PA, Suba EJ, Lawler-Heavner J, Elashry-Stowers D, Wei LL, Toft DO, Sullivan WP, Horwitz KB, Edwards DP. Immunologic analysis of human breast cancer progesterone receptors. 1. Immunoaffinity purification of transformed receptors and production of monoclonal antibodies. Biochemistry. 26: 6250-62. PMID 3689773 DOI: 10.1021/bi00393a045  0.68
1987 LeMaistra CF, Edwards DP, Krolick KA, McGuire WL. An immunotoxin cytotoxic for breast cancer cells in vitro Cancer Research. 47: 730-734. PMID 3492266  0.68
1986 Edwards DP, Dressler LG, Zava DT, McGuire WL. Monoclonal antibody characterization of a tumor-associated breast cancer antigen Progress in Clinical and Biological Research. 204: 71-88. PMID 2421350  0.68
1985 Ciocca DR, Puy LA, Edwards DP, Adams DJ, McGuire WL. The presence of an estrogen-regulated protein detected by monoclonal antibody in abnormal human endometrium Journal of Clinical Endocrinology and Metabolism. 60: 137-143. PMID 3880561  0.68
1985 Schneider SL, Zeltzer PM, Edwards DP, McGuire WL. Monoclonal antibodies to human medulloblastoma cell line TE671: Reactivity in neuroectodermal cell lines and tumors Federation Proceedings. 44.  0.68
1984 Ciocca DR, Adams DJ, Edwards DP, Bjercke RJ, McGuire WL. Estrogen-induced 24K protein in MCF-7 breast cancer cells is localized in granules Breast Cancer Research and Treatment. 4: 261-268. PMID 6518292 DOI: 10.1007/BF01806037  0.68
1984 McGuire WL, Adams DJ, Edwards DP. Estrogen-regulated protein in human breast cancer Journal of Steroid Biochemistry. 20: 73-75. PMID 6368988 DOI: 10.1016/0022-4731(84)90191-2  0.68
1984 Grose C, Edwards DP, Weigle KA, Friedrichs WE, Mcguire WL. Varicella-zoster virus-specific gpl40: A highly immunogenic and disulfide-linked structural glycoprotein Virology. 132: 138-146. PMID 6320530 DOI: 10.1016/0042-6822(84)90098-9  0.68
1983 Adams DJ, Hajj H, Bitar KG, Edwards DP, McGuire WL. Purification of an estrogen-regulated breast cancer protein by monoclonal antibody affinity chromatography Endocrinology. 113: 415-417. PMID 6861712  0.68
1983 Ciocca DR, Adams DJ, Edwards DP, Bjercke RJ, McGuire WL. Distribution of an estrogen-induced protein with a molecular weight of 24,000 in normal and malignant human tissues and cells Cancer Research. 43: 1204-1210. PMID 6825091  0.68
1983 Adams DJ, Edwards DP, McGuire WL. Estrogen regulation of specific proteins as a mode of hormone action in human breast cancer Biomembranes. 11: 389-414. PMID 6338951  0.68
1982 Ciocca DR, Adams DJ, Bjercke RJ, Edwards DP, McGuire WL. Lmmunohistochemical detection of an estrogen-regulated protein by monoclonal antibodies Cancer Research. 42: 4256-4257. PMID 7049357  0.68
1982 Edwards DP, McGuire WL. Estrogen action in human breast cancer (Review) Anticancer Research. 2: 297-308. PMID 6762142  0.68
1981 Edwards DP, Adams DJ, McGuire WL. Estradiol stimulates synthesis of a major intracellular protein in a human breast cancer cell line (MCF-7) Breast Cancer Research and Treatment. 1: 209-223. PMID 7348573 DOI: 10.1007/BF01806261  0.68
1981 Edwards DP, Adams DJ, McGuire WL. Estrogen regulation of growth and specific protein synthesis in human breast cancer cells in tissue culture Advances in Experimental Medicine and Biology. 138: 133-149. PMID 7342712  0.68
1981 Edwards DP, Adams DJ, McGuire WL. Specific protein synthesis regulated by estrogen in human breast cancer Journal of Steroid Biochemistry. 15: 247-259. PMID 7339251 DOI: 10.1016/0022-4731(81)90281-8  0.68
1980 Edwards DP, McGuire WL. 17α-Estradiol is a biologically active estrogen in human breast cancer cells in tissue culture Endocrinology. 107: 884-891. PMID 7408775  0.68
1980 Edwards DP, Adams DJ, Savage N, McGuire WL. Estrogen induced synthesis of specific proteins in human breast cancer cells Biochemical and Biophysical Research Communications. 93: 804-812. PMID 7387677 DOI: 10.1016/0006-291X(80)91148-1  0.68
1980 Edwards DP, Martin PM, Horwitz KB, Chamness GC, McGuire WL. Subcellular compartmentalization of estrogen receptors in human breast cancer cells. Experimental Cell Research. 127: 197-213. PMID 7379864 DOI: 10.1016/0014-4827(80)90427-9  0.68
1980 Edwards DP, Murthy SR, McGuire WL. Effects of Estrogen and Antiestrogen on DNA Polymerase in Human Breast Cancer Cancer Research. 40: 1722-1726. PMID 7371001  0.68
1980 Adams DJ, Edwards DP, McGuire WL. Estrogen regulation of specific messinger RNA's in human breast cancer cells Biochemical and Biophysical Research Communications. 97: 1354-1361. PMID 7213361 DOI: 10.1016/S0006-291X(80)80016-7  0.68
1979 Edwards DP, Chamness GC, McGuire WL. Estrogen and progesterone receptor proteins in breast cancer Bba - Reviews On Cancer. 560: 457-486. PMID 391286 DOI: 10.1016/0304-419X(79)90013-1  0.68
1977 O'Conner JL, Edwards DP, Bransome ED. Localizing steroid dehydrogenase activity on acrylamide gels: The perils of "histochemistry", Analytical Biochemistry. 78: 205-212. PMID 848742 DOI: 10.1016/0003-2697(77)90025-2  0.68
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