Tim-Tak Kwok - Publications

Affiliations: 
The Chinese University of Hong Kong, Hong Kong, Hong Kong 
Area:
Biochemistry

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Yeung CL, Tsang TY, Yau PL, Kwok TT. Human papillomavirus type 16 E6 suppresses microRNA-23b expression in human cervical cancer cells through DNA methylation of the host gene C9orf3. Oncotarget. PMID 28077801 DOI: 10.18632/oncotarget.14555  0.8
2012 Sun J, Yeung CA, Co NN, Tsang TY, Yau E, Luo K, Wu P, Wa JC, Fung KP, Kwok TT, Liu F. Clitocine reversal of P-glycoprotein associated multi-drug resistance through down-regulation of transcription factor NF-κB in R-HepG2 cell line. Plos One. 7: e40720. PMID 22927901 DOI: 10.1371/journal.pone.0040720  0.8
2011 Chen CY, Sun JG, Huang ZZ, Kwok TT, Fung KP, Wu P, Liu FY. Synthesis and antiproliferative activities of novel 5'-Schiff-base group substituted psoralen derivatives. Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 46: 64-9. PMID 21462896  0.8
2011 Sun JG, Chen CY, Luo KW, Yeung CL, Tsang TY, Huang ZZ, Wu P, Fung KP, Kwok TT, Liu FY. 3,5-Dimethyl-H-furo[3,2-g]chromen-7-one as a potential anticancer drug by inducing p53-dependent apoptosis in human hepatoma HepG2 cells. Chemotherapy. 57: 162-72. PMID 21454974 DOI: 10.1159/000326915  0.8
2011 Tsang TY, Tang WY, Chan JY, Co NN, Au Yeung CL, Yau PL, Kong SK, Fung KP, Kwok TT. P-glycoprotein enhances radiation-induced apoptotic cell death through the regulation of miR-16 and Bcl-2 expressions in hepatocellular carcinoma cells. Apoptosis : An International Journal On Programmed Cell Death. 16: 524-35. PMID 21336967 DOI: 10.1007/s10495-011-0581-5  0.8
2011 Au Yeung CL, Tsang TY, Yau PL, Kwok TT. Human papillomavirus type 16 E6 induces cervical cancer cell migration through the p53/microRNA-23b/urokinase-type plasminogen activator pathway. Oncogene. 30: 2401-10. PMID 21242962 DOI: 10.1038/onc.2010.613  0.8
2010 Au Yeung CL, Tsang WP, Tsang TY, Co NN, Yau PL, Kwok TT. HPV-16 E6 upregulation of DNMT1 through repression of tumor suppressor p53. Oncology Reports. 24: 1599-604. PMID 21042757 DOI: 10.3892/or-00001023  0.8
2010 Co NN, Tsang WP, Tsang TY, Yeung CL, Yau PL, Kong SK, Kwok TT. AF1q enhancement of gamma irradiation-induced apoptosis by up-regulation of BAD expression via NF-kappaB in human squamous carcinoma A431 cells. Oncology Reports. 24: 547-54. PMID 20596645 DOI: 10.3892/or-00000891  0.8
2010 Tsang WP, Ng EK, Ng SS, Jin H, Yu J, Sung JJ, Kwok TT. Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer. Carcinogenesis. 31: 350-8. PMID 19926638 DOI: 10.1093/carcin/bgp181  0.8
2010 Tsang WP, Kwok TT. Epigallocatechin gallate up-regulation of miR-16 and induction of apoptosis in human cancer cells. The Journal of Nutritional Biochemistry. 21: 140-6. PMID 19269153 DOI: 10.1016/j.jnutbio.2008.12.003  0.8
2009 Tsang TY, Tsang SW, Lai KP, Tsang WP, Co NN, Kwok TT. Facilitation of drug resistance development by gamma-irradiation in human cancer cells. Oncology Reports. 22: 921-6. PMID 19724874 DOI: 10.3892/or_00000518  0.8
2009 Tsang TY, Tang WY, Tsang WP, Co NN, Kong SK, Kwok TT. Mechanistic study on growth suppression and apoptosis induction by targeting hepatoma-derived growth factor in human hepatocellular carcinoma HepG2 cells. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 24: 253-62. PMID 19710540 DOI: 10.1159/000233250  0.8
2009 Ng EK, Tsang WP, Ng SS, Jin HC, Yu J, Li JJ, Röcken C, Ebert MP, Kwok TT, Sung JJ. MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer. British Journal of Cancer. 101: 699-706. PMID 19638978 DOI: 10.1038/sj.bjc.6605195  0.8
2009 Liu FY, Luo KW, Yu ZM, Co NN, Wu SH, Wu P, Fung KP, Kwok TT. Suillin from the mushroom Suillus placidus as potent apoptosis inducer in human hepatoma HepG2 cells. Chemico-Biological Interactions. 181: 168-74. PMID 19616521 DOI: 10.1016/j.cbi.2009.07.008  0.8
2009 Wu F, Wang J, Wang Y, Kwok TT, Kong SK, Wong C. Estrogen-related receptor alpha (ERRalpha) inverse agonist XCT-790 induces cell death in chemotherapeutic resistant cancer cells. Chemico-Biological Interactions. 181: 236-42. PMID 19464277 DOI: 10.1016/j.cbi.2009.05.008  0.8
2009 Tsang WP, Kwok TT. The miR-18a* microRNA functions as a potential tumor suppressor by targeting on K-Ras. Carcinogenesis. 30: 953-9. PMID 19372139 DOI: 10.1093/carcin/bgp094  0.8
2009 Lee RKY, Ong RCY, Cheung JYN, Li YC, Chan JYW, Lee MMS, Suen YK, Fung KP, Ho HP, Yu B, Li M, Kwok TT, Kong SK. Polyphyllin D - A potential anti-cancer agent to kill hepatocarcinoma cells with multi-drug resistance Current Chemical Biology. 3: 89-99.  0.8
2008 Co NN, Tsang WP, Wong TW, Cheung HH, Tsang TY, Kong SK, Kwok TT. Oncogene AF1q enhances doxorubicin-induced apoptosis through BAD-mediated mitochondrial apoptotic pathway. Molecular Cancer Therapeutics. 7: 3160-8. PMID 18852119 DOI: 10.1158/1535-7163.MCT-08-0416  0.64
2008 Tsang WP, Kwok TT. Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3. Apoptosis : An International Journal On Programmed Cell Death. 13: 1215-22. PMID 18758960 DOI: 10.1007/s10495-008-0256-z  0.8
2008 Tsang TY, Tang WY, Tsang WP, Co NN, Kong SK, Kwok TT. Downregulation of hepatoma-derived growth factor activates the Bad-mediated apoptotic pathway in human cancer cells. Apoptosis : An International Journal On Programmed Cell Death. 13: 1135-47. PMID 18651222 DOI: 10.1007/s10495-008-0241-6  0.8
2008 Lee KY, Geng H, Ng KM, Yu J, van Hasselt A, Cao Y, Zeng YX, Wong AH, Wang X, Ying J, Srivastava G, Lung ML, Wang LD, Kwok TT, Levi BZ, et al. Epigenetic disruption of interferon-gamma response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas. Oncogene. 27: 5267-76. PMID 18469857 DOI: 10.1038/onc.2008.147  0.8
2007 Lui JC, Wong JW, Suen YK, Kwok TT, Fung KP, Kong SK. Cordycepin induced eryptosis in mouse erythrocytes through a Ca2+-dependent pathway without caspase-3 activation. Archives of Toxicology. 81: 859-65. PMID 17541556 DOI: 10.1007/s00204-007-0214-5  0.8
2007 Tsang WP, Wong TW, Cheung AH, Co CN, Kwok TT. Induction of drug resistance and transformation in human cancer cells by the noncoding RNA CUDR. Rna (New York, N.Y.). 13: 890-8. PMID 17416635 DOI: 10.1261/rna.359007  0.64
2007 Wong RP, Tsang WP, Chau PY, Co NN, Tsang TY, Kwok TT. p53-R273H gains new function in induction of drug resistance through down-regulation of procaspase-3. Molecular Cancer Therapeutics. 6: 1054-61. PMID 17363498 DOI: 10.1158/1535-7163.MCT-06-0336  0.8
2007 Tsang WP, Kwok TT. Riboregulator H19 induction of MDR1-associated drug resistance in human hepatocellular carcinoma cells. Oncogene. 26: 4877-81. PMID 17297456 DOI: 10.1038/sj.onc.1210266  0.8
2006 Tsang WP, Kong SK, Kwok TT. Epidermal growth factor induction of resistance to topoisomerase II toxins in human squamous carcinoma A431 cells. Oncology Reports. 16: 789-93. PMID 16969495  0.8
2006 Ho FY, Tsang WP, Kong SK, Kwok TT. The critical role of caspases activation in hypoxia/reoxygenation induced apoptosis. Biochemical and Biophysical Research Communications. 345: 1131-7. PMID 16716256 DOI: 10.1016/j.bbrc.2006.04.178  0.8
2005 Tsang WP, Ho FY, Fung KP, Kong SK, Kwok TT. p53-R175H mutant gains new function in regulation of doxorubicin-induced apoptosis. International Journal of Cancer. Journal International Du Cancer. 114: 331-6. PMID 15578696 DOI: 10.1002/ijc.20818  0.8
2004 Tang WY, Chau SP, Tsang WP, Kong SK, Kwok TT. The role of Raf-1 in radiation resistance of human hepatocellular carcinoma Hep G2 cells. Oncology Reports. 12: 1349-54. PMID 15547762  0.8
2004 Li YC, Fung KP, Kwok TT, Lee CY, Suen YK, Kong SK. Mitochondria-targeting drug oligomycin blocked P-glycoprotein activity and triggered apoptosis in doxorubicin-resistant HepG2 cells. Chemotherapy. 50: 55-62. PMID 15211078 DOI: 10.1159/000077803  0.8
2003 Lui PP, Chan FL, Suen YK, Kwok TT, Kong SK. The nucleus of HeLa cells contains tubular structures for Ca2+ signaling with the involvement of mitochondria. Biochemical and Biophysical Research Communications. 308: 826-33. PMID 12927793 DOI: 10.1016/S0006-291X(03)01469-4  0.8
2003 Tsang WP, Chau SP, Kong SK, Fung KP, Kwok TT. Reactive oxygen species mediate doxorubicin induced p53-independent apoptosis. Life Sciences. 73: 2047-58. PMID 12899928 DOI: 10.1016/S0024-3205(03)00566-6  0.8
2003 Tsang WP, Chau SP, Fung KP, Kong SK, Kwok TT. Modulation of multidrug resistance-associated protein 1 (MRP1) by p53 mutant in Saos-2 cells. Cancer Chemotherapy and Pharmacology. 51: 161-6. PMID 12647018 DOI: 10.1007/s00280-002-0551-2  0.8
2002 Li YC, Fung KP, Kwok TT, Lee CY, Suen YK, Kong SK. Mitochondrial targeting drug lonidamine triggered apoptosis in doxorubicin-resistant HepG2 cells. Life Sciences. 71: 2729-40. PMID 12383880 DOI: 10.1016/S0024-3205(02)02103-3  0.8
2001 Ko S, Kwok TT, Fung KP, Choy YM, Lee CY, Kong SK. Tumour necrosis factor induced an early release of superoxide and a late mitochondrial membrane depolarization in L929 cells. Increase in the production of superoxide is not sufficient to mimic the action of TNF. Biological Signals and Receptors. 10: 326-35. PMID 11490098  0.8
2001 Kwok TT, Chen P, Liu PY, Tang YC, Kong SK, Fung KP, Choy YM. The anti-tumour effect of Klebsiella pneumoniae capsular polysaccharides. Biological Signals and Receptors. 10: 294-8. PMID 11490094  0.8
2001 Chung LY, Cheung TC, Kong SK, Fung KP, Choy YM, Chan ZY, Kwok TT. Induction of apoptosis by green tea catechins in human prostate cancer DU145 cells. Life Sciences. 68: 1207-14. PMID 11228105 DOI: 10.1016/S0024-3205(00)01020-1  0.8
2000 Yuen WF, Fung KP, Lee CY, Choy YM, Kong SK, Ko S, Kwok TT. Hyperthermia and tumour necrosis factor-alpha induced apoptosis via mitochondrial damage. Life Sciences. 67: 725-32. PMID 12659178 DOI: 10.1016/S0024-3205(00)00656-1  0.8
2000 Ko S, Yuen WF, Fung KP, Lee CY, Choy YM, Cheng HK, Kwok TT, Kong SK. Reversal of TNF-alpha resistance by hyperthermia: role of mitochondria. Life Sciences. 67: 3113-21. PMID 11125848  0.8
2000 Ko S, Kwok TT, Fung KP, Choy YM, Lee CY, Kong SK. Slow rise of Ca2+ and slow release of reactive oxygen species are two cross-talked events important in tumour necrosis factor-alpha-mediated apoptosis. Free Radical Research. 33: 295-304. PMID 10993483  0.8
2000 Wong TW, Yu HY, Kong SK, Fung KP, Kwok TT. The decrease of mitochondrial NADH dehydrogenease and drug induced apoptosis in doxorubicin resistant A431 cells. Life Sciences. 67: 1111-8. PMID 10954045 DOI: 10.1016/S0024-3205(00)00699-8  0.8
2000 Kok LD, Wong YP, Wu TW, Chan HC, Kwok TT, Fung KP. Morin hydrate: a potential antioxidant in minimizing the free-radicals-mediated damage to cardiovascular cells by anti-tumor drugs. Life Sciences. 67: 91-9. PMID 10896033 DOI: 10.1016/S0024-3205(00)00605-6  0.8
1999 Liong E, Kong SK, Au KK, Li JY, Xu GY, Lee YL, Kwok TT, Choy YM, Lee CY, Fung KP. Inhibition of glucose uptake and suppression of glucose transporter 1 mRNA expression in L929 cells by tumour necrosis factor-alpha. Life Sciences. 65: PL215-20. PMID 10574229  0.8
1999 Liong E, Kong SK, Au KK, Li JY, Xu GY, Lee YL, Kwok TT, Choy YM, Lee CY, Fung KP. Enhanced cytotoxicity and suppression of glucose transport rate by combined treatment of recombinant human tumour necrosis factor-alpha and hyperthermia on L929 cells. Life Sciences. 65: PL81-6. PMID 10466752  0.8
1998 Lui PP, Kong SK, Kwok TT, Lee CY. The nucleus of HeLa cell contains tubular structures for Ca2+ signalling. Biochemical and Biophysical Research Communications. 247: 88-93. PMID 9636660 DOI: 10.1006/bbrc.1998.8649  0.8
1997 Au KK, Liong E, Li JY, Li PS, Liew CC, Kwok TT, Choy YM, Lee CY, Fung KP. Increases in mRNA levels of glucose transporters types 1 and 3 in Ehrlich ascites tumor cells during tumor development. Journal of Cellular Biochemistry. 67: 131-5. PMID 9328846 DOI: 10.1002/(SICI)1097-4644(19971001)67:1<131::AID-JCB13>3.0.CO;2-K  0.8
1995 Mok SC, Kwok TT, Berkowitz RS, Barrett AJ, Tsui FW. Overexpression of the protein tyrosine phosphatase, nonreceptor type 6 (PTPN6), in human epithelial ovarian cancer. Gynecologic Oncology. 57: 299-303. PMID 7774833 DOI: 10.1006/gyno.1995.1146  0.8
1994 Kwok TT, Mok CH, Menton-Brennan L. Up-regulation of a mutant form of p53 by doxorubicin in human squamous carcinoma cells. Cancer Research. 54: 2834-6. PMID 8187062  0.8
1994 Sakata K, Kwok TT, Gordon GR, Waleh NS, Sutherland RM. Resistance to verapamil sensitization of multidrug-resistant cells grown as multicellular spheroids. International Journal of Cancer. Journal International Du Cancer. 59: 282-6. PMID 7927930 DOI: 10.1002/ijc.2910590222  0.8
1992 Kwok TT, Sutherland RM. Cell cycle dependence of epidermal growth factor induced radiosensitization. International Journal of Radiation Oncology, Biology, Physics. 22: 525-7. PMID 1735690 DOI: 10.1016/0360-3016(92)90867-H  0.8
1992 Kwok TT, Sutherland RM. Reoxygenation associated radiosensitization after chronic hypoxia: effect of temperature and oxygen tension. International Journal of Radiation Oncology, Biology, Physics. 22: 411-4. PMID 1735670 DOI: 10.1016/0360-3016(92)90843-7  0.8
1991 Kwok TT, Sutherland RM. The influence of cell-cell contact on radiosensitivity of human squamous carcinoma cells. Radiation Research. 126: 52-7. PMID 2020738  0.8
1991 Kwok TT, Sutherland RM. Epidermal growth factor modification of radioresistance related to cell-cell interactions. International Journal of Radiation Oncology, Biology, Physics. 20: 315-8. PMID 1991695 DOI: 10.1016/0360-3016(91)90112-H  0.8
1991 Kwok TT, Sutherland RM. Differences in EGF related radiosensitisation of human squamous carcinoma cells with high and low numbers of EGF receptors. British Journal of Cancer. 64: 251-4. PMID 1892752 DOI: 10.1038/bjc.1991.286  0.8
1989 Kwok TT, Sutherland RM. Enhancement of sensitivity of human squamous carcinoma cells to radiation by epidermal growth factor. Journal of the National Cancer Institute. 81: 1020-4. PMID 2786570 DOI: 10.1093/jnci/81.13.1020  0.8
1989 Kwok TT, Sutherland RM. The radiation response of cells recovering after chronic hypoxia. Radiation Research. 119: 261-7. PMID 2756117  0.8
1988 Kwok TT, Twentyman PR. Effects of changes in oxygen tension, pH, and glucose concentration on the response to CCNU of EMT6 mouse tumor monolayer cells and multicellular spheroids. International Journal of Radiation Oncology, Biology, Physics. 14: 1221-9. PMID 3384723 DOI: 10.1016/0360-3016(88)90401-4  0.8
1987 Kwok TT, Twentyman PR. Use of a tritiated thymidine suicide technique in the study of the cytotoxic drug response of cells located at different depths within multicellular spheroids. British Journal of Cancer. 55: 367-74. PMID 3034319 DOI: 10.1038/bjc.1987.74  0.8
1987 Choy YM, Kwok TT, Fung KP. Effect of L-histidine on plasma glucose and cholesterol and liver glycogen of mice bearing Ehrlich ascites tumour Nutrition Reports International. 35: 49-56.  0.8
1986 Kwok TT, Twentyman PR. The effect of pre- or post-treatment with a calmodulin inhibitor (trifluoperazine) on the response to cytotoxic agents of cells within small EMT6/Ca/VJAC spheroids. International Journal of Radiation Oncology, Biology, Physics. 12: 1359-62. PMID 3759556 DOI: 10.1016/0360-3016(86)90171-9  0.8
1986 Choy YM, Fung KP, Kwok TT, Choi E, Lee CY. L-histidine inhibits the growth of Ehrlich ascites tumour. Chemotherapy. 32: 138-41. PMID 3754506 DOI: 10.1159/000238405  0.8
1986 Choy YM, Kwok TT, Fung KP. Effect of L-histidine on alkaline phosphatase activity in the liver and tumour cells of mice bearing Ehrlich ascites tumour Nutrition Reports International. 33: 459-463.  0.8
1985 Kwok TT, Twentyman PR. The relationship between tumour geometry and the response of tumour cells to cytotoxic drugs--an in vitro study using EMT6 multicellular spheroids. International Journal of Cancer. 35: 675-82. PMID 3997287  0.8
1985 Kwok TT, Twentyman PR. The response to cytotoxic drugs of EMT6 cells treated either as intact or disaggregated spheroids. British Journal of Cancer. 51: 211-8. PMID 3966978 DOI: 10.1038/bjc.1985.31  0.8
1983 Choy YM, Kwok TT, Fung KP, Lee CY. Effect of garlic, Chinese medicinal drugs and amino acids on growth of Erlich ascites tumor cells in mice. The American Journal of Chinese Medicine. 11: 69-73. PMID 6660216 DOI: 10.1142/S0192415X83000112  0.8
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