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Charles N. Serhan - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Pharmacology, Immunology, Biochemistry
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Year Citation  Score
2023 Reinertsen AF, Libreros S, Nshimiyimana R, Serhan CN, Hansen TV. Metabolization of Resolvin E4 by ω-Oxidation in Human Neutrophils: Synthesis and Biological Evaluation of 20-Hydroxy-Resolvin E4 (20-OH-RvE4). Acs Pharmacology & Translational Science. 6: 1898-1908. PMID 38093843 DOI: 10.1021/acsptsci.3c00201  0.305
2023 Rao Z, Brunner E, Giszas B, Iyer-Bierhoff A, Gerstmeier J, Börner F, Jordan PM, Pace S, Meyer KPL, Hofstetter RK, Merk D, Paulenz C, Heinzel T, Grunert PC, Stallmach A, ... Serhan CN, et al. Glucocorticoids regulate lipid mediator networks by reciprocal modulation of 15-lipoxygenase isoforms affecting inflammation resolution. Proceedings of the National Academy of Sciences of the United States of America. 120: e2302070120. PMID 37603745 DOI: 10.1073/pnas.2302070120  0.334
2023 Libreros S, Nshimiyimana R, Lee B, Serhan CN. Infectious Neutrophil deployment is regulated by Resolvin D4. Blood. PMID 37295018 DOI: 10.1182/blood.2022019145  0.313
2023 Serhan CN, Chiang N. Resolvins and cysteinyl-containing pro-resolving mediators activate resolution of infectious inflammation and tissue regeneration. Prostaglandins & Other Lipid Mediators. 166: 106718. PMID 36813255 DOI: 10.1016/j.prostaglandins.2023.106718  0.306
2023 Serhan CN, Sulciner ML. Resolution medicine in cancer, infection, pain and inflammation: are we on track to address the next Pandemic? Cancer Metastasis Reviews. 1-5. PMID 36781545 DOI: 10.1007/s10555-023-10091-5  0.309
2022 Nshimiyimana R, Glynn SJ, Serhan CN, Petasis NA. Stereocontrolled total synthesis of Resolvin D4 and 17()-Resolvin D4. Organic & Biomolecular Chemistry. PMID 36345797 DOI: 10.1039/d2ob01697d  0.551
2022 Vidar Hansen T, Serhan CN. Protectins: Their biosynthesis, metabolism and structure-functions. Biochemical Pharmacology. 206: 115330. PMID 36341938 DOI: 10.1016/j.bcp.2022.115330  0.32
2022 Nshimiyimana R, Lam TF, Aggarwal S, Serhan CN, Petasis NA. First stereoselective total synthesis of 4(),5()-oxido-17()-hydroxy-6(),8(),10(),13(),15(),19()-docosahexaenoic acid, the biosynthetic precursor of resolvins D3 and D4. Rsc Advances. 12: 11613-11618. PMID 35481084 DOI: 10.1039/d2ra01537d  0.565
2022 Serhan CN, Libreros S, Nshimiyimana R. E-series resolvin metabolome, biosynthesis and critical role of stereochemistry of specialized pro-resolving mediators (SPMs) in inflammation-resolution: Preparing SPMs for long COVID-19, human clinical trials, and targeted precision nutrition. Seminars in Immunology. 101597. PMID 35227568 DOI: 10.1016/j.smim.2022.101597  0.389
2022 Miek L, Jordan PM, Günther K, Pace S, Beyer T, Kowalak D, Hoerr V, Löffler B, Tuchscherr L, Serhan CN, Gerstmeier J, Werz O. Staphylococcus aureus controls eicosanoid and specialized pro-resolving mediator production via lipoteichoic acid. Immunology. PMID 35143048 DOI: 10.1111/imm.13449  0.329
2021 Shay AE, Nshimiyimana R, Samuelsson B, Petasis NA, Haeggström JZ, Serhan CN. Human leukocytes selectively convert 4,5-epoxy-resolvin to resolvin D3, resolvin D4, and a cys-resolvin isomer. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34911767 DOI: 10.1073/pnas.2116559118  0.671
2021 Chiang N, Sakuma M, Rodriguez AR, Spur BW, Irimia D, Serhan CN. Resolvin T-series Reduce Neutrophil Extracellular Traps. Blood. PMID 34814186 DOI: 10.1182/blood.2021013422  0.305
2021 Panigrahy D, Gilligan MM, Serhan CN, Kashfi K. Resolution of inflammation: An organizing principle in biology and medicine. Pharmacology & Therapeutics. 107879. PMID 33915177 DOI: 10.1016/j.pharmthera.2021.107879  0.327
2021 Sansbury BE, Li X, Wong B, Riley CO, Shay AE, Nshimiyimana R, Petasis NA, Serhan CN, Spite M. PCTR1 enhances repair and bacterial clearance in skin wounds. The American Journal of Pathology. PMID 33689792 DOI: 10.1016/j.ajpath.2021.02.015  0.538
2020 Libreros S, Shay AE, Nshimiyimana R, Fichtner D, Martin MJ, Wourms N, Serhan CN. A New E-Series Resolvin: RvE4 Stereochemistry and Function in Efferocytosis of Inflammation-Resolution. Frontiers in Immunology. 11: 631319. PMID 33643307 DOI: 10.3389/fimmu.2020.631319  0.349
2020 Ganesan R, Henkels KM, Shah K, De La Rosa X, Libreros S, Cheemarla NR, Serhan CN, Gomez-Cambronero J. D-series Resolvins activate Phospholipase D in phagocytes during inflammation and resolution. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 33047359 DOI: 10.1096/fj.201903025RR  0.325
2020 Andreakos E, Papadaki M, Serhan CN. Dexamethasone, pro-resolving lipid mediators and resolution of inflammation in COVID-19. Allergy. PMID 32956495 DOI: 10.1111/All.14595  0.336
2020 Serhan CN, Gupta SK, Perretti M, Godson C, Brennan E, Li Y, Soehnlein O, Shimizu T, Werz O, Chiurchiù V, Azzi A, Dubourdeau M, Gupta SS, Schopohl P, Hoch M, et al. The Atlas of Inflammation Resolution (AIR). Molecular Aspects of Medicine. 100894. PMID 32893032 DOI: 10.1016/J.Mam.2020.100894  0.319
2020 Fishbein A, Hammock BD, Serhan CN, Panigrahy D. Carcinogenesis: Failure of resolution of inflammation? Pharmacology & Therapeutics. 107670. PMID 32891711 DOI: 10.1016/J.Pharmthera.2020.107670  0.43
2020 Chiang N, Serhan CN. Specialized pro-resolving mediator network: an update on production and actions. Essays in Biochemistry. PMID 32885825 DOI: 10.1042/Ebc20200018  0.436
2020 Tourki B, Kain V, Shaikh SR, Leroy X, Serhan CN, Halade GV. Deficit of resolution receptor magnifies inflammatory leukocyte directed cardiorenal and endothelial dysfunction with signs of cardiomyopathy of obesity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32543720 DOI: 10.1096/Fj.202000495Rr  0.318
2020 Panigrahy D, Gilligan MM, Huang S, Gartung A, Cortés-Puch I, Sime PJ, Phipps RP, Serhan CN, Hammock BD. Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19? Cancer Metastasis Reviews. PMID 32385712 DOI: 10.1007/S10555-020-09889-4  0.457
2020 Yang M, Lippestad M, Hodges RR, Fjærvoll HK, Fjærvoll KA, Bair JA, Utheim TP, Serhan CN, Dartt DA. RvE1 uses the LTB receptor BLT1 to increase [Ca] and stimulate mucin secretion in cultured rat and human conjunctival goblet cells. The Ocular Surface. PMID 32361084 DOI: 10.1016/J.Jtos.2020.04.011  0.315
2020 Sønderskov J, Tungen JE, Palmas F, Dalli J, Serhan CN, Stenstrøm Y, Vidar Hansen T. Stereoselective synthesis of MaR2n-3 DPA Tetrahedron Letters. 61: 151510. DOI: 10.1016/J.Tetlet.2019.151510  0.327
2019 Kooij G, Derada Troletti C, Leuti A, Norris PC, Riley I, Albanese M, Ruggieri S, Libreros S, van der Pol SMA, van Het Hof B, Schell Y, Guerrera G, Buttari F, Mercuri NB, Centonze D, ... ... Serhan CN, et al. Specialized pro-resolving lipid mediators are differentially altered in peripheral blood of patients with multiple sclerosis and attenuate monocyte and blood-brain barrier dysfunction. Haematologica. PMID 31780628 DOI: 10.3324/Haematol.2019.219519  0.38
2019 Zhou Y, Lei J, Xie Q, Wu L, Jin S, Guo B, Wang X, Yan G, Zhang Q, Zhao H, Zhang J, Zhang X, Wang J, Gu J, Liu X, ... ... Serhan CN, et al. Fibrinogen-like protein 2 controls sepsis catabasis by interacting with resolvin Dp5. Science Advances. 5: eaax0629. PMID 31763448 DOI: 10.1126/Sciadv.Aax0629  0.404
2019 Norris PC, Libreros S, Serhan CN. Resolution metabolomes activated by hypoxic environment. Science Advances. 5: eaax4895. PMID 31681846 DOI: 10.1126/Sciadv.Aax4895  0.435
2019 Chiang N, Libreros S, Norris PC, de la Rosa X, Serhan CN. Maresin 1 activates LGR6 receptor promoting phagocyte immunoresolvent functions. The Journal of Clinical Investigation. PMID 31657786 DOI: 10.1172/Jci129448  0.395
2019 Levy BD, Abdulnour RE, Tavares A, Brüggemann TR, Norris PC, Bai Y, Ai X, Serhan CN. Cys-LTs' Pro-phlogistic Lung Actions Are Regulated by Cys-Maresins. The Journal of Allergy and Clinical Immunology. PMID 31622689 DOI: 10.1016/J.Jaci.2019.09.028  0.382
2019 Jouvene CC, Shay AE, Soens MA, Norris PC, Haeggström JZ, Serhan CN. Biosynthetic metabolomes of cysteinyl-containing immunoresolvents. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201902003R. PMID 31589826 DOI: 10.1096/Fj.201902003R  0.383
2019 Dartt DA, Hodges RR, Serhan CN. Immunoresolvent Resolvin D1 Maintains the Health of the Ocular Surface. Advances in Experimental Medicine and Biology. 1161: 13-25. PMID 31562618 DOI: 10.1007/978-3-030-21735-8_3  0.33
2019 Becker F, Romero E, Goetzmann J, Hasselschwert DL, Dray B, Vanchiere J, Fontenot J, Yun JW, Norris PC, White L, Musso M, Serhan CN, Alexander JS, Gavins FNE. Endogenous Specialized Proresolving Mediator Profiles in a Novel Experimental Model of Lymphatic Obstruction and Intestinal Inflammation in African Green Monkeys. The American Journal of Pathology. 189: 1953-1972. PMID 31547920 DOI: 10.1016/J.Ajpath.2019.05.013  0.388
2019 Yang J, Zaman MM, Vlasakov I, Roy R, Huang L, Martin CR, Freedman SD, Serhan CN, Moses MA. Adipocytes promote ovarian cancer chemoresistance. Scientific Reports. 9: 13316. PMID 31527632 DOI: 10.1038/S41598-019-49649-1  0.351
2019 Krashia P, Cordella A, Nobili A, La Barbera L, Federici M, Leuti A, Campanelli F, Natale G, Marino G, Calabrese V, Vedele F, Ghiglieri V, Picconi B, Di Lazzaro G, Schirinzi T, ... ... Serhan CN, et al. Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease. Nature Communications. 10: 3945. PMID 31477726 DOI: 10.1038/S41467-019-11928-W  0.317
2019 Rao Z, Pace S, Jordan PM, Bilancia R, Troisi F, Börner F, Andreas N, Kamradt T, Menche D, Rossi A, Serhan CN, Gerstmeier J, Werz O. Vacuolar (H)-ATPase Critically Regulates Specialized Proresolving Mediator Pathways in Human M2-like Monocyte-Derived Macrophages and Has a Crucial Role in Resolution of Inflammation. Journal of Immunology (Baltimore, Md. : 1950). PMID 31300512 DOI: 10.4049/Jimmunol.1900236  0.376
2019 Cherpokova D, Jouvene CC, Libreros S, DeRoo E, Chu L, de la Rosa X, Norris P, Wagner DD, Serhan CN. Resolvin D4 attenuates the severity of pathological thrombosis in mice. Blood. PMID 31300403 DOI: 10.1182/Blood.2018886317  0.398
2019 Panigrahy D, Gartung A, Yang J, Yang H, Gilligan MM, Sulciner ML, Bhasin SS, Bielenberg DR, Chang J, Schmidt BA, Piwowarski J, Fishbein A, Soler-Ferran D, Sparks MA, Staffa SJ, ... ... Serhan CN, et al. Preoperative stimulation of resolution and inflammation blockade eradicates micrometastases. The Journal of Clinical Investigation. 130. PMID 31205032 DOI: 10.1172/Jci127282  0.343
2019 Gilligan MM, Gartung A, Sulciner ML, Norris PC, Sukhatme VP, Bielenberg DR, Huang S, Kieran MW, Serhan CN, Panigrahy D. Aspirin-triggered proresolving mediators stimulate resolution in cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 30862734 DOI: 10.1073/Pnas.1804000116  0.396
2019 Werner M, Jordan PM, Romp E, Czapka A, Rao Z, Kretzer C, Koeberle A, Garscha U, Pace S, Claesson HE, Serhan CN, Werz O, Gerstmeier J. Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802509R. PMID 30735438 DOI: 10.1096/Fj.201802509R  0.365
2019 Serhan CN, de la Rosa X, Jouvene C. Novel mediators and mechanisms in the resolution of infectious inflammation: evidence for vagus regulation. Journal of Internal Medicine. 286: 240-258. PMID 30565762 DOI: 10.1111/Joim.12871  0.464
2019 Davis-Porada J, Serhan C, Norris P, Lipsky P, Salmon J. 3 Polyunsaturated fatty acids (PUFAs) and specialized pro-resolving mediators (SPMs) are decreased in plasma and serum from SLE patients compared to healthy controls Lupus Science & Medicine. 6. DOI: 10.1136/Lupus-2019-Lsm.3  0.323
2019 Davis-Porada J, Serhan C, Norris P, Lipsky P, Salmon JE. Thu0279 Polyunsaturated Fatty Acids (Pufas) And Specialized Pro-Resolving Mediators (Spms) Are Decreased In Plasma And Serum From Sle Patients Compared To Healthy Controls Annals of the Rheumatic Diseases. 78: 417-418. DOI: 10.1136/Annrheumdis-2019-Eular.2126  0.322
2018 Hansen TV, Vik A, Serhan CN. The Protectin Family of Specialized Pro-resolving Mediators: Potent Immunoresolvents Enabling Innovative Approaches to Target Obesity and Diabetes. Frontiers in Pharmacology. 9: 1582. PMID 30705632 DOI: 10.3389/Fphar.2018.01582  0.403
2018 Norris PC, Skulas-Ray AC, Riley I, Richter CK, Kris-Etherton PM, Jensen GL, Serhan CN, Maddipati KR. Identification of specialized pro-resolving mediator clusters from healthy adults after intravenous low-dose endotoxin and omega-3 supplementation: a methodological validation. Scientific Reports. 8: 18050. PMID 30575798 DOI: 10.1038/S41598-018-36679-4  0.353
2018 Chiang N, Barnaeva E, Hu X, Marugan J, Southall N, Ferrer M, Serhan CN. Identification of Chemotype Agonists for Human Resolvin D1 Receptor DRV1 with Pro-Resolving Functions. Cell Chemical Biology. PMID 30554914 DOI: 10.1016/J.Chembiol.2018.10.023  0.411
2018 Hansen TV, Tungen JE, Gerstman L, De Matteis R, Colas RA, Vik A, Chiang N, Serhan CN, Kalesse M, Dalli J. Resolving Inflammation - Synthesis, Configurational Assignment and Biological Evaluations of RvD1n-3 DPA. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30511787 DOI: 10.1002/Chem.201806029  0.392
2018 Matte A, Recchiuti A, Federti E, Koehl B, Mintz T, El Nemer W, Tharaux PL, Brousse V, Andolfo I, Lamolinara A, Weinberg O, Siciliano A, Norris PC, Riley IR, Iolascon A, ... Serhan CN, et al. Resolution of sickle cell disease associated inflammation and tissue damage with 17R-Resolvin D1. Blood. PMID 30404812 DOI: 10.1182/Blood-2018-07-865378  0.468
2018 Serhan CN, de la Rosa X, Jouvene CC. Cutting Edge: Human Vagus Produces Specialized Proresolving Mediators of Inflammation with Electrical Stimulation Reducing Proinflammatory Eicosanoids. Journal of Immunology (Baltimore, Md. : 1950). PMID 30355784 DOI: 10.4049/Jimmunol.1800806  0.394
2018 Saban DR, Hodges RR, Mathew R, Reyes NJ, Yu C, Kaye R, Swift W, Botten N, Serhan CN, Dartt DA. Resolvin D1 treatment on goblet cell mucin and immune responses in the chronic allergic eye disease (AED) model. Mucosal Immunology. PMID 30279513 DOI: 10.1038/S41385-018-0089-1  0.314
2018 Tungen JE, Aursnes M, Ramon S, Colas RA, Serhan CN, Olberg DE, Nuruddin S, Willoch F, Hansen TV. Synthesis of protectin D1 analogs: novel pro-resolution and radiotracer agents. Organic & Biomolecular Chemistry. 16: 6818-6823. PMID 30204204 DOI: 10.1039/C8Ob01232F  0.358
2018 Lahvic JL, Ammerman M, Li P, Blair MC, Stillman ER, Fast EM, Robertson AL, Christodoulou C, Perlin JR, Yang S, Chiang N, Norris PC, Daily ML, Redfield SE, Chan IT, ... ... Serhan CN, et al. Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132. Proceedings of the National Academy of Sciences of the United States of America. PMID 30139917 DOI: 10.1073/Pnas.1806077115  0.358
2018 Zhang L, Terrando N, Xu ZZ, Bang S, Jordt SE, Maixner W, Serhan CN, Ji RR. Distinct Analgesic Actions of DHA and DHA-Derived Specialized Pro-Resolving Mediators on Post-operative Pain After Bone Fracture in Mice. Frontiers in Pharmacology. 9: 412. PMID 29765320 DOI: 10.3389/Fphar.2018.00412  0.304
2018 Serhan CN, Levy BD. Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators. The Journal of Clinical Investigation. PMID 29757195 DOI: 10.1172/Jci97943  0.411
2018 Sorokin AV, Norris PC, English JT, Dey AK, Chaturvedi A, Baumer Y, Silverman J, Playford MP, Serhan CN, Mehta NN. Identification of proresolving and inflammatory lipid mediators in human psoriasis. Journal of Clinical Lipidology. PMID 29730187 DOI: 10.1016/J.Jacl.2018.03.091  0.413
2018 Dalli J, Serhan CN. Identification and structure elucidation of the proresolving mediators provides novel leads for resolution pharmacology. British Journal of Pharmacology. PMID 29679485 DOI: 10.1111/Bph.14336  0.443
2018 de la Rosa X, Norris PC, Chiang N, Rodriguez AR, Spur BW, Serhan CN. Identification and Complete Stereochemical Assignments of the New Resolvin Conjugates in Tissue Regeneration in Human Tissues that Stimulate Proresolving Phagocyte Functions and Tissue Regeneration. The American Journal of Pathology. 188: 950-966. PMID 29571326 DOI: 10.1016/J.Ajpath.2018.01.004  0.431
2018 Motwani MP, Colas RA, George MJ, Flint JD, Dalli J, Richard-Loendt A, De Maeyer RP, Serhan CN, Gilroy DW. Pro-resolving mediators promote resolution in a human skin model of UV-killed Escherichia coli-driven acute inflammation. Jci Insight. 3. PMID 29563331 DOI: 10.1172/Jci.Insight.94463  0.454
2018 Hellmann J, Sansbury BE, Wong B, Li X, Singh M, Nuutila K, Chiang N, Eriksson E, Serhan CN, Spite M. Biosynthesis of D-series resolvins in skin provides insights into their role in tissue repair. The Journal of Investigative Dermatology. PMID 29559341 DOI: 10.1016/J.Jid.2018.03.1498  0.374
2018 Norris PC, Serhan CN. Metabololipidomic profiling of functional immunoresolvent clusters and eicosanoids in mammalian tissues. Biochemical and Biophysical Research Communications. PMID 29524409 DOI: 10.1016/J.Bbrc.2018.03.037  0.372
2018 Sham HP, Walker KH, Abdulnour RE, Krishnamoorthy N, Douda DN, Norris PC, Barkas I, Benito-Figueroa S, Colby JK, Serhan CN, Levy BD. 15-epi-Lipoxin A, Resolvin D2, and Resolvin D3 Induce NF-κB Regulators in Bacterial Pneumonia. Journal of Immunology (Baltimore, Md. : 1950). PMID 29523657 DOI: 10.4049/Jimmunol.1602090  0.393
2018 Chiang N, Riley IR, Dalli J, Rodriguez AR, Spur BW, Serhan CN. New maresin conjugates in tissue regeneration pathway counters leukotriene D-stimulated vascular responses. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201701493R. PMID 29490167 DOI: 10.1096/Fj.201701493R  0.419
2018 Halade GV, Kain V, Serhan CN. Immune responsive resolvin D1 programs myocardial infarction-induced cardiorenal syndrome in heart failure. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201701173RR. PMID 29455574 DOI: 10.1096/Fj.201701173Rr  0.329
2018 Winkler JW, Libreros S, De La Rosa X, Sansbury BE, Norris PC, Chiang N, Fichtner D, Keyes GS, Wourms N, Spite M, Serhan CN. Structural insights into Resolvin D4 actions and further metabolites via a new total organic synthesis and validation. Journal of Leukocyte Biology. PMID 29377345 DOI: 10.1002/Jlb.3Mi0617-254R  0.788
2018 Colas RA, Ashton AW, Mukherjee S, Dalli J, Akide-Ndunge OB, Huang H, Desruisseaux MS, Guan F, Jelicks LA, Matos Dos Santos F, Nagajyothi J, Zingman M, Reyes J, Weiss LM, Serhan CN, et al. Trypanosoma cruzi produces the specialized proresolving mediators Resolvin D1, Resolvin D5 and Resolvin E2. Infection and Immunity. PMID 29358332 DOI: 10.1128/Iai.00688-17  0.336
2018 Werz O, Gerstmeier J, Libreros S, De la Rosa X, Werner M, Norris PC, Chiang N, Serhan CN. Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity. Nature Communications. 9: 59. PMID 29302056 DOI: 10.1038/S41467-017-02538-5  0.387
2017 Motwani MP, Bennett F, Norris PC, Maini AA, George MJ, Newson J, Henderson A, Hobbs AJ, Tepper M, White B, Serhan CN, MacAllister R, Gilroy DW. Potent anti-inflammatory and pro-resolving effects of anabasum in a human model of self-resolving acute inflammation. Clinical Pharmacology and Therapeutics. PMID 29238967 DOI: 10.1002/Cpt.980  0.452
2017 Dalli J, Serhan CN. Pro-Resolving Mediators in Regulating and Conferring Macrophage Function. Frontiers in Immunology. 8: 1400. PMID 29163481 DOI: 10.3389/Fimmu.2017.01400  0.444
2017 Dalli J, Serhan CN. Immunoresolvents signaling molecules at intersection between the brain and immune system. Current Opinion in Immunology. 50: 48-54. PMID 29154174 DOI: 10.1016/J.Coi.2017.10.007  0.334
2017 Hamilton JA, Hasturk H, Kantarci A, Serhan CN, Van Dyke T. Atherosclerosis, Periodontal Disease, and Treatment with Resolvins. Current Atherosclerosis Reports. 19: 57. PMID 29110146 DOI: 10.1007/S11883-017-0696-4  0.373
2017 Reátegui E, Jalali F, Khankhel AH, Wong E, Cho H, Lee J, Serhan CN, Dalli J, Elliott H, Irimia D. Microscale arrays for the profiling of start and stop signals coordinating human-neutrophil swarming. Nature Biomedical Engineering. 1. PMID 29057147 DOI: 10.1038/S41551-017-0094  0.38
2017 Sima C, Montero E, Nguyen D, Freire M, Norris P, Serhan CN, Van Dyke TE. ERV1 Overexpression in Myeloid Cells Protects against High Fat Diet Induced Obesity and Glucose Intolerance. Scientific Reports. 7: 12848. PMID 28993702 DOI: 10.1038/S41598-017-13185-7  0.326
2017 Lippestad M, Hodges RR, Utheim TP, Serhan CN, Dartt DA. Resolvin D1 Increases Mucin Secretion in Cultured Rat Conjunctival Goblet Cells via Multiple Signaling Pathways. Investigative Ophthalmology & Visual Science. 58: 4530-4544. PMID 28892824 DOI: 10.1167/Iovs.17-21914  0.326
2017 Serhan CN, Chiang N, Dalli J. New pro-resolving n-3 mediators bridge resolution of infectious inflammation to tissue regeneration. Molecular Aspects of Medicine. PMID 28802833 DOI: 10.1016/J.Mam.2017.08.002  0.373
2017 Norris PC, Libreros S, Chiang N, Serhan CN. A cluster of immunoresolvents links coagulation to innate host defense in human blood. Science Signaling. 10. PMID 28765512 DOI: 10.1126/Scisignal.Aan1471  0.331
2017 Hansen TV, Dalli J, Serhan CN. The Novel Lipid Mediator PD1n-3DPA: An Overview of the Structural Elucidation, Synthesis, Biosynthesis and Bioactions. Prostaglandins & Other Lipid Mediators. PMID 28602942 DOI: 10.1016/J.Prostaglandins.2017.06.003  0.423
2017 Gobbetti T, Dalli J, Colas RA, Federici Canova D, Aursnes M, Bonnet D, Alric L, Vergnolle N, Deraison C, Hansen TV, Serhan CN, Perretti M. Protectin D1n-3 DPA and resolvin D5n-3 DPA are effectors of intestinal protection. Proceedings of the National Academy of Sciences of the United States of America. PMID 28356517 DOI: 10.1073/Pnas.1617290114  0.448
2017 Chiang N, Serhan CN. Structural elucidation and physiologic functions of specialized pro-resolving mediators and their receptors. Molecular Aspects of Medicine. PMID 28336292 DOI: 10.1016/J.Mam.2017.03.005  0.44
2017 Serhan CN. Discovery of specialized pro-resolving mediators marks the dawn of resolution physiology and pharmacology. Molecular Aspects of Medicine. PMID 28263773 DOI: 10.1016/J.Mam.2017.03.001  0.391
2017 Lee S, Nakahira K, Dalli J, Siempos II, Norris PC, Colas RA, Moon JS, Shinohara M, Hisata S, Howrylak JA, Suh GY, Ryter SW, Serhan CN, Choi AM. NLRP3 Inflammasome Deficiency Protects Against Microbial Sepsis via Increased Lipoxin B4 Synthesis. American Journal of Respiratory and Critical Care Medicine. PMID 28245134 DOI: 10.1164/Rccm.201604-0892Oc  0.351
2017 English JT, Norris PC, Hodges RR, Dartt DA, Serhan CN. Identification and Profiling of Specialized Pro-Resolving Mediators in Human Tears by Lipid Mediator Metabolomics. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 117: 17-27. PMID 28237084 DOI: 10.1016/J.Plefa.2017.01.004  0.413
2017 Fedirko V, McKeown-Eyssen G, Serhan CN, Barry EL, Sandler RS, Figueiredo JC, Ahnen DJ, Bresalier RS, Robertson DJ, Anderson CW, Baron JA. Plasma lipoxin A4 and resolvin D1 are not associated with reduced adenoma risk in a randomized trial of aspirin to prevent colon adenomas. Molecular Carcinogenesis. PMID 28218420 DOI: 10.1002/Mc.22629  0.302
2017 Serhan CN. Treating inflammation and infection in the 21st century: new hints from decoding resolution mediators and mechanisms. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28087575 DOI: 10.1096/Fj.201601222R  0.433
2017 Dalli J, Colas RA, Arnardottir H, Serhan CN. Vagal Regulation of Group 3 Innate Lymphoid Cells and the Immunoresolvent PCTR1 Controls Infection Resolution. Immunity. PMID 28065837 DOI: 10.1016/J.Immuni.2016.12.009  0.393
2017 Dalli J, Serhan C. Macrophage Proresolving Mediators-the When and Where. Microbiology Spectrum. 4. PMID 27337457 DOI: 10.1128/Microbiolspec.Mchd-0001-2014  0.439
2016 Chiang N, de la Rosa X, Libreros S, Serhan CN. Novel Resolvin D2 Receptor Axis in Infectious Inflammation. Journal of Immunology (Baltimore, Md. : 1950). PMID 27994074 DOI: 10.4049/Jimmunol.1601650  0.388
2016 Freire MO, Dalli J, Serhan CN, Van Dyke TE. Neutrophil Resolvin E1 Receptor Expression and Function in Type 2 Diabetes. Journal of Immunology (Baltimore, Md. : 1950). PMID 27994073 DOI: 10.4049/Jimmunol.1601543  0.311
2016 Hodges RR, Li D, Shatos MA, Serhan CN, Dartt DA. Lipoxin A4 Counter-regulates Histamine-stimulated Glycoconjugate Secretion in Conjunctival Goblet Cells. Scientific Reports. 6: 36124. PMID 27824117 DOI: 10.1038/Srep36124  0.364
2016 Colas RA, Dalli J, Chiang N, Vlasakov I, Sanger JM, Riley IR, Serhan CN. Identification and Actions of the Maresin 1 Metabolome in Infectious Inflammation. Journal of Immunology (Baltimore, Md. : 1950). PMID 27799313 DOI: 10.4049/Jimmunol.1600837  0.425
2016 Dalli J, Vlasakov I, Riley IR, Rodriguez AR, Spur BW, Petasis NA, Chiang N, Serhan CN. Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages. Proceedings of the National Academy of Sciences of the United States of America. 113: 12232-12237. PMID 27791009 DOI: 10.1073/Pnas.1607003113  0.618
2016 Primdahl KG, Aursnes M, Walker ME, Colas RA, Serhan CN, Dalli J, Hansen TV, Vik A. Synthesis of 13(R)-Hydroxy-7Z,10Z,13R,14E,16Z,19Z Docosapentaenoic Acid (13R-HDPA) and Its Biosynthetic Conversion to the 13-Series Resolvins. Journal of Natural Products. PMID 27704804 DOI: 10.1021/Acs.Jnatprod.6B00634  0.373
2016 Titos E, Rius B, López-Vicario C, Alcaraz-Quiles J, García-Alonso V, Lopategi A, Dalli J, Lozano JJ, Arroyo V, Delgado S, Serhan CN, Clària J. Signaling and Immunoresolving Actions of Resolvin D1 in Inflamed Human Visceral Adipose Tissue. Journal of Immunology (Baltimore, Md. : 1950). PMID 27647830 DOI: 10.4049/Jimmunol.1502522  0.367
2016 Dalli J, Colas RA, Quintana C, Barragan-Bradford D, Hurwitz S, Levy BD, Choi AM, Serhan CN, Baron RM. Human Sepsis Eicosanoid and Proresolving Lipid Mediator Temporal Profiles: Correlations With Survival and Clinical Outcomes. Critical Care Medicine. PMID 27632672 DOI: 10.1097/Ccm.0000000000002014  0.324
2016 Chiurchiù V, Leuti A, Dalli J, Jacobsson A, Battistini L, Maccarrone M, Serhan CN. Proresolving lipid mediators resolvin D1, resolvin D2, and maresin 1 are critical in modulating T cell responses. Science Translational Medicine. 8: 353ra111. PMID 27559094 DOI: 10.1126/Scitranslmed.Aaf7483  0.359
2016 Arnardottir HH, Dalli J, Norling LV, Colas RA, Perretti M, Serhan CN. Resolvin D3 Is Dysregulated in Arthritis and Reduces Arthritic Inflammation. Journal of Immunology (Baltimore, Md. : 1950). PMID 27534559 DOI: 10.4049/Jimmunol.1502268  0.363
2016 Hansen TV, Dalli J, Serhan CN. Selective identification of specialized pro-resolving lipid mediators from their biosynthetic double di-oxygenation isomers. Rsc Advances. 6: 28820-28829. PMID 27525060 DOI: 10.1039/C6Ra00414H  0.395
2016 Tsoyi K, Hall SR, Dalli J, Colas RA, Ghanta S, Ith B, Coronata A, Fredenburgh LE, Baron RM, Choi AM, Serhan CN, Liu X, Perrella MA. Carbon Monoxide Improves Efficacy of Mesenchymal Stromal Cells During Sepsis by Production of Specialized Proresolving Lipid Mediators. Critical Care Medicine. PMID 27513357 DOI: 10.1097/Ccm.0000000000001999  0.302
2016 Colby JK, Abdulnour RE, Sham HP, Dalli J, Colas RA, Winkler JW, Hellmann J, Wong B, Cui Y, El-Chemaly S, Petasis NA, Spite M, Serhan CN, Levy BD. Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia. The American Journal of Pathology. PMID 27171898 DOI: 10.1016/J.Ajpath.2016.03.011  0.811
2016 Norling LV, Headland SE, Dalli J, Arnardottir HH, Haworth O, Jones HR, Irimia D, Serhan CN, Perretti M. Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis. Jci Insight. 1: e85922. PMID 27158677 DOI: 10.1172/Jci.Insight.85922  0.368
2016 Elajami TK, Colas RA, Dalli J, Chiang N, Serhan CN, Welty FK. Specialized proresolving lipid mediators in patients with coronary artery disease and their potential for clot remodeling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27121596 DOI: 10.1096/Fj.201500155R  0.347
2016 Hodges RR, Li D, Shatos MA, Bair JA, Lippestad M, Serhan CN, Dartt DA. Lipoxin A4 activates ALX/FPR2 receptor to regulate conjunctival goblet cell secretion. Mucosal Immunology. PMID 27072607 DOI: 10.1038/Mi.2016.33  0.334
2016 Shinohara M, Serhan CN. Novel Endogenous Proresolving Molecules. Journal of Atherosclerosis and Thrombosis. PMID 27052783 DOI: 10.5551/Jat.33928  0.449
2016 Dalli J, Sanger JM, Rodriguez AR, Chiang N, Spur BW, Serhan CN. Identification and Actions of a Novel Third Maresin Conjugate in Tissue Regeneration: MCTR3. Plos One. 11: e0149319. PMID 26881986 DOI: 10.1371/Journal.Pone.0149319  0.398
2016 Ramon S, Dalli J, Sanger JM, Winkler JW, Aursnes M, Tungen JE, Hansen TV, Serhan CN. The Protectin PCTR1 Is Produced by Human M2 Macrophages and Enhances Resolution of Infectious Inflammation. The American Journal of Pathology. PMID 26878209 DOI: 10.1016/J.Ajpath.2015.12.012  0.799
2016 Norris PC, Arnardottir H, Sanger JM, Fichtner D, Keyes GS, Serhan CN. Resolvin D3 multi-level proresolving actions are host protective during infection. Prostaglandins, Leukotrienes, and Essential Fatty Acids. PMID 26858146 DOI: 10.1016/J.Plefa.2016.01.001  0.429
2016 Winkler JW, Orr SK, Dalli J, Cheng CY, Sanger JM, Chiang N, Petasis NA, Serhan CN. Resolvin D4 stereoassignment and its novel actions in host protection and bacterial clearance. Scientific Reports. 6: 18972. PMID 26743932 DOI: 10.1038/Srep18972  0.81
2016 Cianci E, Recchiuti A, Trubiani O, Diomede F, Marchisio M, Miscia S, Colas RA, Dalli J, Serhan CN, Romano M. Human Periodontal Stem Cells Release Specialized Proresolving Mediators and Carry Immunomodulatory and Prohealing Properties Regulated by Lipoxins. Stem Cells Translational Medicine. 5: 20-32. PMID 26607175 DOI: 10.5966/Sctm.2015-0163  0.433
2016 Arnardottir H, Orr SK, Dalli J, Serhan CN. Human milk proresolving mediators stimulate resolution of acute inflammation. Mucosal Immunology. 9: 757-66. PMID 26462421 DOI: 10.1038/Mi.2015.99  0.376
2016 Shinohara M, Serhan CN. Novel endogenous proresolving molecules: Essential fatty acid-derived and gaseous mediators in the resolution of inflammation Journal of Atherosclerosis and Thrombosis. 23: 655-664. DOI: 10.5551/jat.3392  0.353
2016 Lahvic JL, Ammerman MB, Li P, Yang S, Chiang N, Chase M, Weis O, Zhou Y, Serhan C, Zon LI. Eicosanoid-GPCR Signaling Enhances Hematopoiesis and Marrow Transplant Blood. 128: 495-495. DOI: 10.1182/Blood.V128.22.495.495  0.34
2016 Gilligan MM, Sulciner ML, Gus-Brautbar Y, Ramon S, Colas RA, Huang S, Serhan CN, Panigrahy D. Abstract 766: Control of lung cancer with aspirin-triggered stimulation of resolution Cancer Research. 76: 766-766. DOI: 10.1158/1538-7445.Am2016-766  0.351
2016 Dalli J, Chiang N, Serhan C. AB0042 Identification of Sulfido-Conjugated Mediators That Promote Resolution of Infection and Organ Protection Annals of the Rheumatic Diseases. 75: 911.2-911. DOI: 10.1136/Annrheumdis-2016-Eular.6149  0.429
2015 Wang CW, Colas RA, Dalli JP, Arnardottir HH, Nguyen D, Hasturk H, Chiang N, Van Dyke TE, Serhan CN. Maresin 1 Biosynthesis and Pro-resolving Anti-Infective Functions with Human Localized Aggressive Periodontitis Leukocytes. Infection and Immunity. PMID 26667839 DOI: 10.1128/Iai.01131-15  0.418
2015 Zhu M, Wang X, Hjorth E, Colas RA, Schroeder L, Granholm AC, Serhan CN, Schultzberg M. Pro-Resolving Lipid Mediators Improve Neuronal Survival and Increase Aβ42 Phagocytosis. Molecular Neurobiology. PMID 26650044 DOI: 10.1007/S12035-015-9544-0  0.34
2015 Abdulnour RE, Sham HP, Douda DN, Colas RA, Dalli J, Bai Y, Ai X, Serhan CN, Levy BD. Aspirin-triggered resolvin D1 is produced during self-resolving gram-negative bacterial pneumonia and regulates host immune responses for the resolution of lung inflammation. Mucosal Immunology. PMID 26647716 DOI: 10.1038/Mi.2015.129  0.401
2015 Berrueta L, Muskaj I, Olenich S, Butler T, Badger GJ, Colas RA, Spite M, Serhan CN, Langevin HM. Stretching Impacts Inflammation Resolution in Connective Tissue. Journal of Cellular Physiology. PMID 26588184 DOI: 10.1002/Jcp.25263  0.375
2015 Aursnes M, Tungen JE, Colas RA, Vlasakov I, Dalli J, Serhan CN, Hansen TV. Synthesis of the 16S,17S-Epoxyprotectin Intermediate in the Biosynthesis of Protectins by Human Macrophages. Journal of Natural Products. PMID 26580578 DOI: 10.1021/Acs.Jnatprod.5B00574  0.419
2015 Orr SK, Butler KL, Hayden D, Tompkins RG, Serhan CN, Irimia D. Gene Expression of Proresolving Lipid Mediator Pathways Is Associated With Clinical Outcomes in Trauma Patients. Critical Care Medicine. PMID 26488221 DOI: 10.1097/Ccm.0000000000001312  0.328
2015 Hsiao HM, Thatcher TH, Colas RA, Serhan CN, Phipps RP, Sime PJ. Resolvin D1 Reduces Emphysema and Chronic Inflammation. The American Journal of Pathology. PMID 26468975 DOI: 10.1016/J.Ajpath.2015.08.008  0.358
2015 Croasdell A, Thatcher TH, Kottmann RM, Colas RA, Dalli J, Serhan CN, Sime PJ, Phipps RP. Resolvins attenuate inflammation and promote resolution in cigarette smoke-exposed human macrophages. American Journal of Physiology. Lung Cellular and Molecular Physiology. 309: L888-901. PMID 26301452 DOI: 10.1152/Ajplung.00125.2015  0.41
2015 Chiang N, Dalli J, Colas RA, Serhan CN. Identification of resolvin D2 receptor mediating resolution of infections and organ protection. The Journal of Experimental Medicine. 212: 1203-17. PMID 26195725 DOI: 10.1084/Jem.20150225  0.414
2015 Ramirez JL, de Almeida Oliveira G, Calvo E, Dalli J, Colas RA, Serhan CN, Ribeiro JM, Barillas-Mury C. A mosquito lipoxin/lipocalin complex mediates innate immune priming in Anopheles gambiae. Nature Communications. 6: 7403. PMID 26100162 DOI: 10.1038/Ncomms8403  0.301
2015 Börgeson E, Johnson AM, Lee YS, Till A, Syed GH, Ali-Shah ST, Guiry PJ, Dalli J, Colas RA, Serhan CN, Sharma K, Godson C. Lipoxin A4 Attenuates Obesity-Induced Adipose Inflammation and Associated Liver and Kidney Disease. Cell Metabolism. 22: 125-37. PMID 26052006 DOI: 10.1016/J.Cmet.2015.05.003  0.314
2015 Kain V, Ingle KA, Colas RA, Dalli J, Prabhu SD, Serhan CN, Joshi M, Halade GV. Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular function. Journal of Molecular and Cellular Cardiology. 84: 24-35. PMID 25870158 DOI: 10.1016/J.Yjmcc.2015.04.003  0.36
2015 Serhan CN, Chiang N, Dalli J. The resolution code of acute inflammation: Novel pro-resolving lipid mediators in resolution. Seminars in Immunology. PMID 25857211 DOI: 10.1016/J.Smim.2015.03.004  0.411
2015 Orr SK, Colas RA, Dalli J, Chiang N, Serhan CN. Proresolving actions of a new resolvin D1 analog mimetic qualifies as an immunoresolvent. American Journal of Physiology. Lung Cellular and Molecular Physiology. 308: L904-11. PMID 25770181 DOI: 10.1152/Ajplung.00370.2014  0.445
2015 Dalli J, Ramon S, Norris PC, Colas RA, Serhan CN. Novel proresolving and tissue-regenerative resolvin and protectin sulfido-conjugated pathways. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 2120-36. PMID 25713027 DOI: 10.1096/Fj.14-268441  0.401
2015 Dalli J, Kraft BD, Colas RA, Shinohara M, Fredenburgh LE, Hess DR, Chiang N, Welty-Wolf KE, Choi AM, Piantadosi CA, Serhan CN. Proresolving Lipid Mediator Profiles in Baboon Pneumonia are Regulated by Inhaled Carbon Monoxide. American Journal of Respiratory Cell and Molecular Biology. PMID 25568926 DOI: 10.1165/Rcmb.2014-0299Oc  0.349
2015 Krishnamoorthy N, Burkett PR, Dalli J, Abdulnour RE, Colas R, Ramon S, Phipps RP, Petasis NA, Kuchroo VK, Serhan CN, Levy BD. Cutting edge: maresin-1 engages regulatory T cells to limit type 2 innate lymphoid cell activation and promote resolution of lung inflammation. Journal of Immunology (Baltimore, Md. : 1950). 194: 863-7. PMID 25539814 DOI: 10.4049/Jimmunol.1402534  0.589
2015 Van Dyke TE, Hasturk H, Kantarci A, Freire MO, Nguyen D, Dalli J, Serhan CN. Proresolving nanomedicines activate bone regeneration in periodontitis. Journal of Dental Research. 94: 148-56. PMID 25389003 DOI: 10.1177/0022034514557331  0.361
2015 Serhan CN, Chiang N, Dalli J, Levy BD. Lipid mediators in the resolution of inflammation. Cold Spring Harbor Perspectives in Biology. 7: a016311. PMID 25359497 DOI: 10.1101/Cshperspect.A016311  0.426
2015 Serhan CN, Dalli J, Colas RA, Winkler JW, Chiang N. Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome. Biochimica Et Biophysica Acta. 1851: 397-413. PMID 25139562 DOI: 10.1016/J.Bbalip.2014.08.006  0.805
2015 Wang X, Zhu M, Hjorth E, Cortés-Toro V, Eyjolfsdottir H, Graff C, Nennesmo I, Palmblad J, Eriksdotter M, Sambamurti K, Fitzgerald JM, Serhan CN, Granholm AC, Schultzberg M. Resolution of inflammation is altered in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 40-50.e1-2. PMID 24530025 DOI: 10.1016/J.Jalz.2013.12.024  0.307
2015 Mattè A, Recchiuti A, Serhan C, Siciliano A, Federti E, Weinberg O, Kalish B, Brugnara C, De Franceschi L. Resolvin D1 and Resolvin D2 Protect Against Hypoxia/Reoxygenation Induced Lung and Kidney Damage in a Sickle Cell Mouse Model of Acute Vaso-Occlusive Crisis Blood. 126: 966-966. DOI: 10.1182/Blood.V126.23.966.966  0.402
2015 Gilligan M, Sulciner M, Ramon S, Colas R, Huang S, Serhan C, Panigrahy D. Control of Lung Cancer with Aspirin-Triggered Stimulation of Resolution The Faseb Journal. 29. DOI: 10.1096/Fasebj.29.1_Supplement.54.6  0.316
2014 Abdulnour RE, Dalli J, Colby JK, Krishnamoorthy N, Timmons JY, Tan SH, Colas RA, Petasis NA, Serhan CN, Levy BD. Maresin 1 biosynthesis during platelet-neutrophil interactions is organ-protective. Proceedings of the National Academy of Sciences of the United States of America. 111: 16526-31. PMID 25369934 DOI: 10.1073/Pnas.1407123111  0.618
2014 Dalli J, Chiang N, Serhan CN. Identification of 14-series sulfido-conjugated mediators that promote resolution of infection and organ protection. Proceedings of the National Academy of Sciences of the United States of America. 111: E4753-61. PMID 25324525 DOI: 10.1073/Pnas.1415006111  0.406
2014 Tungen JE, Aursnes M, Vik A, Ramon S, Colas RA, Dalli J, Serhan CN, Hansen TV. Synthesis and anti-inflammatory and pro-resolving activities of 22-OH-PD1, a monohydroxylated metabolite of protectin D1. Journal of Natural Products. 77: 2241-7. PMID 25247845 DOI: 10.1021/Np500498J  0.378
2014 Tungen JE, Aursnes M, Dalli J, Arnardottir H, Serhan CN, Hansen TV. Total synthesis of the anti-inflammatory and pro-resolving lipid mediator MaR1n-3 DPA utilizing an sp(3) -sp(3) Negishi cross-coupling reaction. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 14575-8. PMID 25225129 DOI: 10.1002/Chem.201404721  0.337
2014 Shinohara M, Kibi M, Riley IR, Chiang N, Dalli J, Kraft BD, Piantadosi CA, Choi AM, Serhan CN. Cell-cell interactions and bronchoconstrictor eicosanoid reduction with inhaled carbon monoxide and resolvin D1. American Journal of Physiology. Lung Cellular and Molecular Physiology. 307: L746-57. PMID 25217660 DOI: 10.1152/Ajplung.00166.2014  0.337
2014 Arnardottir HH, Dalli J, Colas RA, Shinohara M, Serhan CN. Aging delays resolution of acute inflammation in mice: reprogramming the host response with novel nano-proresolving medicines. Journal of Immunology (Baltimore, Md. : 1950). 193: 4235-44. PMID 25217168 DOI: 10.4049/Jimmunol.1401313  0.383
2014 Tang H, Liu Y, Yan C, Petasis NA, Serhan CN, Gao H. Protective actions of aspirin-triggered (17R) resolvin D1 and its analogue, 17R-Hydroxy-19-Para-Fluorophenoxy-Resolvin D1 Methyl Ester, in C5a-Dependent IgG immune complex-induced inflammation and lung injury Journal of Immunology. 193: 3769-3778. PMID 25172497 DOI: 10.4049/Jimmunol.1400942  0.624
2014 Hua J, Jin Y, Chen Y, Inomata T, Lee HS, Chauhan SK, Petasis NA, Serhan CN, Dana R. The resolvin D1 analogue controls maturation of dendritic cells and suppresses alloimmunity in corneal transplantation Investigative Ophthalmology and Visual Science. 55: 5944-5951. PMID 25146982 DOI: 10.1167/Iovs.14-14356  0.55
2014 Deng B, Wang CW, Arnardottir HH, Li Y, Cheng CY, Dalli J, Serhan CN. Maresin biosynthesis and identification of maresin 2, a new anti-inflammatory and pro-resolving mediator from human macrophages. Plos One. 9: e102362. PMID 25036362 DOI: 10.1371/Journal.Pone.0102362  0.465
2014 Serhan CN. Pro-resolving lipid mediators are leads for resolution physiology. Nature. 510: 92-101. PMID 24899309 DOI: 10.1038/Nature13479  0.45
2014 Mirakaj V, Dalli J, Granja T, Rosenberger P, Serhan CN. Vagus nerve controls resolution and pro-resolving mediators of inflammation. The Journal of Experimental Medicine. 211: 1037-48. PMID 24863066 DOI: 10.1084/Jem.20132103  0.398
2014 Colas RA, Shinohara M, Dalli J, Chiang N, Serhan CN. Identification and signature profiles for pro-resolving and inflammatory lipid mediators in human tissue. American Journal of Physiology. Cell Physiology. 307: C39-54. PMID 24696140 DOI: 10.1152/Ajpcell.00024.2014  0.379
2014 Buckley CD, Gilroy DW, Serhan CN. Proresolving lipid mediators and mechanisms in the resolution of acute inflammation. Immunity. 40: 315-27. PMID 24656045 DOI: 10.1016/J.Immuni.2014.02.009  0.445
2014 Bäck M, Powell WS, Dahlén SE, Drazen JM, Evans JF, Serhan CN, Shimizu T, Yokomizo T, Rovati GE. Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7. British Journal of Pharmacology. 171: 3551-74. PMID 24588652 DOI: 10.1111/Bph.12665  0.34
2014 Aursnes M, Tungen JE, Vik A, Colas R, Cheng CY, Dalli J, Serhan CN, Hansen TV. Total synthesis of the lipid mediator PD1n-3 DPA: configurational assignments and anti-inflammatory and pro-resolving actions. Journal of Natural Products. 77: 910-6. PMID 24576195 DOI: 10.1021/Np4009865  0.462
2014 Levy BD, Serhan CN. Resolution of acute inflammation in the lung. Annual Review of Physiology. 76: 467-92. PMID 24313723 DOI: 10.1146/Annurev-Physiol-021113-170408  0.357
2014 Spite M, Clària J, Serhan CN. Resolvins, specialized proresolving lipid mediators, and their potential roles in metabolic diseases. Cell Metabolism. 19: 21-36. PMID 24239568 DOI: 10.1016/J.Cmet.2013.10.006  0.395
2014 Ramon S, Bancos S, Serhan CN, Phipps RP. Lipoxin A₄ modulates adaptive immunity by decreasing memory B-cell responses via an ALX/FPR2-dependent mechanism. European Journal of Immunology. 44: 357-69. PMID 24166736 DOI: 10.1002/Eji.201343316  0.363
2014 Winkler J, Dalli J, Colas RA, Arnardottir H, Chiang N, Petasis NA, Serhan CN. Total organic synthesis and stereochemical assignment of resolvin D3 and aspirin-triggered resolvin D3: potent immunoresolvents F1000research. 5. DOI: 10.7490/F1000Research.1097220.1  0.776
2014 Sulciner ML, Mudge DK, Bielenberg DR, Benny O, Dalli J, Huang S, Serhan CN, Kieran MW, Panigrahy D. Abstract 1664: Cancer progression: The failure to resolve Cancer Research. 74: 1664-1664. DOI: 10.1158/1538-7445.Am2014-1664  0.371
2014 Mudge D, Kieran MW, Bielenberg D, Benny O, Dalli J, Huang S, Serhan CN, Panigrahy D. Abstract 1170: Maresin 1: a potent endogenous anti-inflammatory and pro-resolving inhibitor of primary tumor growth and metastasis Cancer Research. 74: 1170-1170. DOI: 10.1158/1538-7445.Am2014-1170  0.428
2014 Dalli J, Colas RA, Serhan CN. Erratum: CORRIGENDUM: Novel n-3 Immunoresolvents: Structures and Actions Scientific Reports. 4. DOI: 10.1038/Srep06726  0.382
2014 Wang X, Granholm A, Fitzgerald JM, Serhan CN, Schultzberg M. P1-099: ALTERED LIPID MEDIATORS AND RECEPTORS OF RESOLUTION IN THE ENTORHINAL CORTEX OF ALZHEIMER'S DISEASE Alzheimer's & Dementia. 10: P338-P338. DOI: 10.1016/J.Jalz.2014.05.335  0.309
2014 Sorokin A, Vaisman B, Thacker S, Yu Z, Fitzgerald J, Serhan C, Remaley A. Dietary omega-3 polyunsaturated fatty acids plus aspirin decreases plasma lipids and increases pro-resolving lipid mediators in apoE-deficient mice Atherosclerosis. 235: e269. DOI: 10.1016/J.Atherosclerosis.2014.05.805  0.321
2014 Tungen JE, Aursnes M, Dalli J, Arnardottir H, Serhan CN, Hansen TV. Cover Picture: Total Synthesis of the Anti-inflammatory and Pro-resolving Lipid Mediator MaR1n−3 DPAUtilizing an sp3-sp3Negishi Cross-Coupling Reaction (Chem. Eur. J. 45/2014) Chemistry - a European Journal. 20: 14533-14533. DOI: 10.1002/Chem.201490186  0.343
2013 Divanovic S, Dalli J, Jorge-Nebert LF, Flick LM, Gálvez-Peralta M, Boespflug ND, Stankiewicz TE, Fitzgerald JM, Somarathna M, Karp CL, Serhan CN, Nebert DW. Contributions of the three CYP1 monooxygenases to pro-inflammatory and inflammation-resolution lipid mediator pathways. Journal of Immunology (Baltimore, Md. : 1950). 191: 3347-57. PMID 23956430 DOI: 10.4049/Jimmunol.1300699  0.425
2013 Orr SK, Palumbo S, Bosetti F, Mount HT, Kang JX, Greenwood CE, Ma DW, Serhan CN, Bazinet RP. Unesterified docosahexaenoic acid is protective in neuroinflammation. Journal of Neurochemistry. 127: 378-93. PMID 23919613 DOI: 10.1111/Jnc.12392  0.384
2013 Mustafa M, Zarrough A, Bolstad AI, Lygre H, Mustafa K, Hasturk H, Serhan C, Kantarci A, Van Dyke TE. Resolvin D1 protects periodontal ligament. American Journal of Physiology. Cell Physiology. 305: C673-9. PMID 23864609 DOI: 10.1152/Ajpcell.00242.2012  0.377
2013 Serhan CN, Chiang N. Resolution phase lipid mediators of inflammation: agonists of resolution. Current Opinion in Pharmacology. 13: 632-40. PMID 23747022 DOI: 10.1016/J.Coph.2013.05.012  0.432
2013 Chiang N, Shinohara M, Dalli J, Mirakaj V, Kibi M, Choi AM, Serhan CN. Inhaled carbon monoxide accelerates resolution of inflammation via unique proresolving mediator-heme oxygenase-1 circuits. Journal of Immunology (Baltimore, Md. : 1950). 190: 6378-88. PMID 23650615 DOI: 10.4049/Jimmunol.1202969  0.43
2013 Koltsida O, Karamnov S, Pyrillou K, Vickery T, Chairakaki AD, Tamvakopoulos C, Sideras P, Serhan CN, Andreakos E. Toll-like receptor 7 stimulates production of specialized pro-resolving lipid mediators and promotes resolution of airway inflammation. Embo Molecular Medicine. 5: 762-75. PMID 23584892 DOI: 10.1002/Emmm.201201891  0.448
2013 Winkler JW, Uddin J, Serhan CN, Petasis NA. Stereocontrolled total synthesis of the potent anti-inflammatory and pro-resolving lipid mediator resolvin D3 and its aspirin-triggered 17 R-epimer Organic Letters. 15: 1424-1427. PMID 23510485 DOI: 10.1021/Ol400484U  0.819
2013 Dalli J, Zhu M, Vlasenko NA, Deng B, Haeggström JZ, Petasis NA, Serhan CN. The novel 13S,14S-epoxy-maresinis converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype Faseb Journal. 27: 2573-2583. PMID 23504711 DOI: 10.1096/Fj.13-227728  0.646
2013 Hsiao HM, Sapinoro RE, Thatcher TH, Croasdell A, Levy EP, Fulton RA, Olsen KC, Pollock SJ, Serhan CN, Phipps RP, Sime PJ. A novel anti-inflammatory and pro-resolving role for resolvin D1 in acute cigarette smoke-induced lung inflammation. Plos One. 8: e58258. PMID 23484005 DOI: 10.1371/Journal.Pone.0058258  0.403
2013 Li D, Hodges RR, Jiao J, Carozza RB, Shatos MA, Chiang N, Serhan CN, Dartt DA. Resolvin D1 and aspirin-triggered resolvin D1 regulate histamine-stimulated conjunctival goblet cell secretion. Mucosal Immunology. 6: 1119-30. PMID 23462912 DOI: 10.1038/Mi.2013.7  0.399
2013 Dalli J, Winkler JW, Colas RA, Arnardottir H, Cheng CY, Chiang N, Petasis NA, Serhan CN. Resolvin D3 and aspirin-triggered resolvin D3 are potent immunoresolvents. Chemistry & Biology. 20: 188-201. PMID 23438748 DOI: 10.1016/J.Chembiol.2012.11.010  0.832
2013 Miyahara T, Runge S, Chatterjee A, Chen M, Mottola G, Fitzgerald JM, Serhan CN, Conte MS. D-series resolvin attenuates vascular smooth muscle cell activation and neointimal hyperplasia following vascular injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 2220-32. PMID 23407709 DOI: 10.1096/Fj.12-225615  0.361
2013 Clària J, Nguyen BT, Madenci AL, Ozaki CK, Serhan CN. Diversity of lipid mediators in human adipose tissue depots. American Journal of Physiology. Cell Physiology. 304: C1141-9. PMID 23364264 DOI: 10.1152/Ajpcell.00351.2012  0.338
2013 Neuhofer A, Zeyda M, Mascher D, Itariu BK, Murano I, Leitner L, Hochbrugger EE, Fraisl P, Cinti S, Serhan CN, Stulnig TM. Impaired local production of proresolving lipid mediators in obesity and 17-HDHA as a potential treatment for obesity-associated inflammation. Diabetes. 62: 1945-56. PMID 23349501 DOI: 10.2337/Db12-0828  0.316
2013 Gao L, Faibish D, Fredman G, Herrera BS, Chiang N, Serhan CN, Van Dyke TE, Gyurko R. Resolvin E1 and chemokine-like receptor 1 mediate bone preservation. Journal of Immunology (Baltimore, Md. : 1950). 190: 689-94. PMID 23241890 DOI: 10.4049/Jimmunol.1103688  0.303
2013 Buckley CD, Gilroy DW, Serhan CN, Stockinger B, Tak PP. The resolution of inflammation. Nature Reviews. Immunology. 13: 59-66. PMID 23197111 DOI: 10.1038/Nri3362  0.362
2013 Giera M, Serhan C, Kloppenburg M, Mayboroda O, Deelder A, Toes R, Ioan-Facsinay A. FRI0027 Pro-resolving lipid mediators are present in the joints of osteoarthritis patients Annals of the Rheumatic Diseases. 71: 318.3-319. DOI: 10.1136/Annrheumdis-2012-Eular.2484  0.383
2012 Jones CN, Dalli J, Dimisko L, Wong E, Serhan CN, Irimia D. Microfluidic chambers for monitoring leukocyte trafficking and humanized nano-proresolving medicines interactions. Proceedings of the National Academy of Sciences of the United States of America. 109: 20560-5. PMID 23185003 DOI: 10.1073/Pnas.1210269109  0.409
2012 Recchiuti A, Serhan CN. Pro-Resolving Lipid Mediators (SPMs) and Their Actions in Regulating miRNA in Novel Resolution Circuits in Inflammation. Frontiers in Immunology. 3: 298. PMID 23093949 DOI: 10.3389/Fimmu.2012.00298  0.429
2012 Gil-Villa AM, Norling LV, Serhan CN, Cordero D, Rojas M, Cadavid A. Aspirin triggered-lipoxin A4 reduces the adhesion of human polymorphonuclear neutrophils to endothelial cells initiated by preeclamptic plasma. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 87: 127-34. PMID 22974760 DOI: 10.1016/J.Plefa.2012.08.003  0.309
2012 Levy BD, Vachier I, Serhan CN. Resolution of inflammation in asthma. Clinics in Chest Medicine. 33: 559-70. PMID 22929102 DOI: 10.1016/J.Ccm.2012.06.006  0.377
2012 Dalli J, Serhan CN. Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators. Blood. 120: e60-72. PMID 22904297 DOI: 10.1182/Blood-2012-04-423525  0.399
2012 Clària J, Dalli J, Yacoubian S, Gao F, Serhan CN. Resolvin D1 and resolvin D2 govern local inflammatory tone in obese fat. Journal of Immunology (Baltimore, Md. : 1950). 189: 2597-605. PMID 22844113 DOI: 10.4049/Jimmunol.1201272  0.392
2012 Giera M, Ioan-Facsinay A, Toes R, Gao F, Dalli J, Deelder AM, Serhan CN, Mayboroda OA. Lipid and lipid mediator profiling of human synovial fluid in rheumatoid arthritis patients by means of LC-MS/MS. Biochimica Et Biophysica Acta. 1821: 1415-24. PMID 22841830 DOI: 10.1016/J.Bbalip.2012.07.011  0.316
2012 Rogerio AP, Haworth O, Croze R, Oh SF, Uddin M, Carlo T, Pfeffer MA, Priluck R, Serhan CN, Levy BD. Resolvin D1 and aspirin-triggered resolvin D1 promote resolution of allergic airways responses. Journal of Immunology (Baltimore, Md. : 1950). 189: 1983-91. PMID 22802419 DOI: 10.4049/Jimmunol.1101665  0.598
2012 Ramon S, Gao F, Serhan CN, Phipps RP. Specialized proresolving mediators enhance human B cell differentiation to antibody-secreting cells. Journal of Immunology (Baltimore, Md. : 1950). 189: 1036-42. PMID 22711890 DOI: 10.4049/Jimmunol.1103483  0.441
2012 Petasis NA, Yang R, Winkler JW, Zhu M, Uddin J, Bazan NG, Serhan CN. Stereocontrolled total synthesis of neuroprotectin D1 / protectin D1 and its aspirin-triggered stereoisomer. Tetrahedron Letters. 53: 1695-1698. PMID 22690022 DOI: 10.1016/J.Tetlet.2012.01.032  0.803
2012 Shinohara M, Mirakaj V, Serhan CN. Functional Metabolomics Reveals Novel Active Products in the DHA Metabolome. Frontiers in Immunology. 3: 81. PMID 22566962 DOI: 10.3389/Fimmu.2012.00081  0.44
2012 Ariel A, Serhan CN. New Lives Given by Cell Death: Macrophage Differentiation Following Their Encounter with Apoptotic Leukocytes during the Resolution of Inflammation. Frontiers in Immunology. 3: 4. PMID 22566890 DOI: 10.3389/Fimmu.2012.00004  0.377
2012 Bazan NG, Eady TN, Khoutorova L, Atkins KD, Hong S, Lu Y, Zhang C, Jun B, Obenaus A, Fredman G, Zhu M, Winkler JW, Petasis NA, Serhan CN, Belayev L. Novel aspirin-triggered neuroprotectin D1 attenuates cerebral ischemic injury after experimental stroke. Experimental Neurology. 236: 122-30. PMID 22542947 DOI: 10.1016/J.Expneurol.2012.04.007  0.778
2012 Chiang N, Fredman G, Bäckhed F, Oh SF, Vickery T, Schmidt BA, Serhan CN. Infection regulates pro-resolving mediators that lower antibiotic requirements. Nature. 484: 524-8. PMID 22538616 DOI: 10.1038/Nature11042  0.584
2012 Norling LV, Dalli J, Flower RJ, Serhan CN, Perretti M. Resolvin D1 limits polymorphonuclear leukocyte recruitment to inflammatory loci: receptor-dependent actions. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1970-8. PMID 22499990 DOI: 10.1161/Atvbaha.112.249508  0.341
2012 Oh SF, Dona M, Fredman G, Krishnamoorthy S, Irimia D, Serhan CN. Resolvin E2 formation and impact in inflammation resolution. Journal of Immunology (Baltimore, Md. : 1950). 188: 4527-34. PMID 22450811 DOI: 10.4049/Jimmunol.1103652  0.654
2012 Krishnamoorthy S, Recchiuti A, Chiang N, Fredman G, Serhan CN. Resolvin D1 receptor stereoselectivity and regulation of inflammation and proresolving microRNAs. The American Journal of Pathology. 180: 2018-27. PMID 22449948 DOI: 10.1016/J.Ajpath.2012.01.028  0.339
2012 Kanter JE, Kramer F, Barnhart S, Averill MM, Vivekanandan-Giri A, Vickery T, Li LO, Becker L, Yuan W, Chait A, Braun KR, Potter-Perigo S, Sanda S, Wight TN, Pennathur S, ... Serhan CN, et al. Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1. Proceedings of the National Academy of Sciences of the United States of America. 109: E715-24. PMID 22308341 DOI: 10.1073/Pnas.1111600109  0.331
2012 Tobin DM, Roca FJ, Oh SF, McFarland R, Vickery TW, Ray JP, Ko DC, Zou Y, Bang ND, Chau TT, Vary JC, Hawn TR, Dunstan SJ, Farrar JJ, Thwaites GE, ... ... Serhan CN, et al. Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections. Cell. 148: 434-46. PMID 22304914 DOI: 10.1016/J.Cell.2011.12.023  0.577
2012 Serhan CN, Dalli J, Karamnov S, Choi A, Park CK, Xu ZZ, Ji RR, Zhu M, Petasis NA. Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 1755-65. PMID 22253477 DOI: 10.1096/Fj.11-201442  0.657
2012 Pillai PS, Leeson S, Porter TF, Owens CD, Kim JM, Conte MS, Serhan CN, Gelman S. Chemical mediators of inflammation and resolution in post-operative abdominal aortic aneurysm patients. Inflammation. 35: 98-113. PMID 21286796 DOI: 10.1007/S10753-011-9294-8  0.391
2011 Park CK, Xu ZZ, Liu T, Lü N, Serhan CN, Ji RR. Resolvin D2 is a potent endogenous inhibitor for transient receptor potential subtype V1/A1, inflammatory pain, and spinal cord synaptic plasticity in mice: distinct roles of resolvin D1, D2, and E1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 18433-8. PMID 22171045 DOI: 10.1523/Jneurosci.4192-11.2011  0.325
2011 Yang R, Chiang N, Oh SF, Serhan CN. Metabolomics-lipidomics of eicosanoids and docosanoids generated by phagocytes. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 14.26. PMID 22048801 DOI: 10.1002/0471142735.Im1426S95  0.636
2011 Park CK, Lü N, Xu ZZ, Liu T, Serhan CN, Ji RR. Resolving TRPV1- and TNF-α-mediated spinal cord synaptic plasticity and inflammatory pain with neuroprotectin D1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 15072-85. PMID 22016541 DOI: 10.1523/Jneurosci.2443-11.2011  0.317
2011 Ji RR, Xu ZZ, Strichartz G, Serhan CN. Emerging roles of resolvins in the resolution of inflammation and pain. Trends in Neurosciences. 34: 599-609. PMID 21963090 DOI: 10.1016/J.Tins.2011.08.005  0.416
2011 Fredman G, Oh SF, Ayilavarapu S, Hasturk H, Serhan CN, Van Dyke TE. Impaired phagocytosis in localized aggressive periodontitis: rescue by Resolvin E1. Plos One. 6: e24422. PMID 21935407 DOI: 10.1371/Journal.Pone.0024422  0.614
2011 Campbell EL, Serhan CN, Colgan SP. Antimicrobial aspects of inflammatory resolution in the mucosa: a role for proresolving mediators. Journal of Immunology (Baltimore, Md. : 1950). 187: 3475-81. PMID 21934099 DOI: 10.4049/Jimmunol.1100150  0.652
2011 Serhan CN, Fredman G, Yang R, Karamnov S, Belayev LS, Bazan NG, Zhu M, Winkler JW, Petasis NA. Novel proresolving aspirin-triggered DHA pathway. Chemistry & Biology. 18: 976-87. PMID 21867913 DOI: 10.1016/J.Chembiol.2011.06.008  0.807
2011 Greene ER, Huang S, Serhan CN, Panigrahy D. Regulation of inflammation in cancer by eicosanoids. Prostaglandins & Other Lipid Mediators. 96: 27-36. PMID 21864702 DOI: 10.1016/J.Prostaglandins.2011.08.004  0.405
2011 Serhan CN, Petasis NA. Resolvins and protectins in inflammation resolution Chemical Reviews. 111: 5922-5943. PMID 21766791 DOI: 10.1021/Cr100396C  0.666
2011 Yang R, Fredman G, Krishnamoorthy S, Agrawal N, Irimia D, Piomelli D, Serhan CN. Decoding functional metabolomics with docosahexaenoyl ethanolamide (DHEA) identifies novel bioactive signals. The Journal of Biological Chemistry. 286: 31532-41. PMID 21757729 DOI: 10.1074/Jbc.M111.237990  0.407
2011 Oh SF, Vickery TW, Serhan CN. Chiral lipidomics of E-series resolvins: aspirin and the biosynthesis of novel mediators. Biochimica Et Biophysica Acta. 1811: 737-47. PMID 21712098 DOI: 10.1016/J.Bbalip.2011.06.007  0.61
2011 Fredman G, Serhan CN. Specialized proresolving mediator targets for RvE1 and RvD1 in peripheral blood and mechanisms of resolution. The Biochemical Journal. 437: 185-97. PMID 21711247 DOI: 10.1042/Bj20110327  0.45
2011 Spite M, Serhan CN. Lipid signatures of unstable atheromas: fossils or a step toward personalized lipidomics-metabolomics? Circulation. Cardiovascular Genetics. 4: 215-7. PMID 21673308 DOI: 10.1161/Circgenetics.111.960344  0.385
2011 Palmer CD, Mancuso CJ, Weiss JP, Serhan CN, Guinan EC, Levy O. 17(R)-Resolvin D1 differentially regulates TLR4-mediated responses of primary human macrophages to purified LPS and live E. coli. Journal of Leukocyte Biology. 90: 459-70. PMID 21653234 DOI: 10.1189/Jlb.0311145  0.396
2011 Serhan CN. The resolution of inflammation: the devil in the flask and in the details. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1441-8. PMID 21532053 DOI: 10.1096/Fj.11-0502Ufm  0.462
2011 Merched AJ, Serhan CN, Chan L. Nutrigenetic disruption of inflammation-resolution homeostasis and atherogenesis. Journal of Nutrigenetics and Nutrigenomics. 4: 12-24. PMID 21474962 DOI: 10.1159/000326890  0.426
2011 Norling LV, Spite M, Yang R, Flower RJ, Perretti M, Serhan CN. Cutting edge: Humanized nano-proresolving medicines mimic inflammation-resolution and enhance wound healing. Journal of Immunology (Baltimore, Md. : 1950). 186: 5543-7. PMID 21460209 DOI: 10.4049/Jimmunol.1003865  0.387
2011 Dartt DA, Hodges RR, Li D, Shatos MA, Lashkari K, Serhan CN. Conjunctival goblet cell secretion stimulated by leukotrienes is reduced by resolvins D1 and E1 to promote resolution of inflammation. Journal of Immunology (Baltimore, Md. : 1950). 186: 4455-66. PMID 21357260 DOI: 10.4049/Jimmunol.1000833  0.339
2011 Serhan CN, Krishnamoorthy S, Recchiuti A, Chiang N. Novel anti-inflammatory--pro-resolving mediators and their receptors. Current Topics in Medicinal Chemistry. 11: 629-47. PMID 21261595 DOI: 10.2174/1568026611109060629  0.428
2011 Oh SF, Pillai PS, Recchiuti A, Yang R, Serhan CN. Pro-resolving actions and stereoselective biosynthesis of 18S E-series resolvins in human leukocytes and murine inflammation. The Journal of Clinical Investigation. 121: 569-81. PMID 21206090 DOI: 10.1172/Jci42545  0.635
2011 Levy BD, Zhang QY, Bonnans C, Primo V, Reilly JJ, Perkins DL, Liang Y, Amin Arnaout M, Nikolic B, Serhan CN. The endogenous pro-resolving mediators lipoxin A4 and resolvin E1 preserve organ function in allograft rejection. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 84: 43-50. PMID 20869861 DOI: 10.1016/J.Plefa.2010.09.002  0.309
2011 Fredman G, Serhan CN. Specialized pro-resolving mediators: wiring the circuitry of effector immune and tissue homeostasis Endodontic Topics. 24: 39-58. DOI: 10.1111/Etp.12010  0.456
2010 Schif-Zuck S, Gross N, Assi S, Rostoker R, Serhan CN, Ariel A. Saturated-efferocytosis generates pro-resolving CD11b low macrophages: modulation by resolvins and glucocorticoids. European Journal of Immunology. 41: 366-79. PMID 21268007 DOI: 10.1002/Eji.201040801  0.443
2010 Spite M, Serhan CN. Novel lipid mediators promote resolution of acute inflammation: Impact of aspirin and statins Circulation Research. 107: 1170-1184. PMID 21071715 DOI: 10.1161/Circresaha.110.223883  0.401
2010 Serhan CN. Novel lipid mediators and resolution mechanisms in acute inflammation: To resolve or not? American Journal of Pathology. 177: 1576-1591. PMID 20813960 DOI: 10.2353/Ajpath.2010.100322  0.457
2010 Ho KJ, Spite M, Owens CD, Lancero H, Kroemer AHK, Pande R, Creager MA, Serhan CN, Conte MS. Aspirin-triggered lipoxin and resolvin E1 modulate vascular smooth muscle phenotype and correlate with peripheral atherosclerosis American Journal of Pathology. 177: 2116-2123. PMID 20709806 DOI: 10.2353/Ajpath.2010.091082  0.415
2010 Bannenberg G, Serhan CN. Specialized pro-resolving lipid mediators in the inflammatory response: An update Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1801: 1260-1273. PMID 20708099 DOI: 10.1016/J.Bbalip.2010.08.002  0.46
2010 Fredman G, Van Dyke TE, Serhan CN. Resolvin E1 regulates adenosine diphosphate activation of human platelets. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 2005-13. PMID 20702811 DOI: 10.1161/Atvbaha.110.209908  0.308
2010 Norling LV, Serhan CN. Profiling in resolving inflammatory exudates identifies novel anti-inflammatory and pro-resolving mediators and signals for termination. Journal of Internal Medicine. 268: 15-24. PMID 20497301 DOI: 10.1111/J.1365-2796.2010.02235.X  0.453
2010 Xu ZZ, Zhang L, Liu T, Park JY, Berta T, Yang R, Serhan CN, Ji RR. Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions. Nature Medicine. 16: 592-7, 1p following . PMID 20383154 DOI: 10.1038/Nm.2123  0.345
2010 Bazan NG, Calandria JM, Serhan CN. Rescue and repair during photoreceptor cell renewal mediated by docosahexaenoic acid-derived neuroprotectin D1. Journal of Lipid Research. 51: 2018-31. PMID 20382842 DOI: 10.1194/Jlr.R001131  0.379
2010 Hattori H, Subramanian KK, Sakai J, Jia Y, Li Y, Porter TF, Loison F, Sarraj B, Kasorn A, Jo H, Blanchard C, Zirkle D, McDonald D, Pai SY, Serhan CN, et al. Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis. Proceedings of the National Academy of Sciences of the United States of America. 107: 3546-51. PMID 20142487 DOI: 10.1073/Pnas.0914351107  0.346
2010 Planagumà A, Pfeffer MA, Rubin G, Croze R, Uddin M, Serhan CN, Levy BD. Lovastatin decreases acute mucosal inflammation via 15-epi-lipoxin A4. Mucosal Immunology. 3: 270-9. PMID 20130564 DOI: 10.1038/Mi.2009.141  0.454
2010 Krishnamoorthy S, Recchiuti A, Chiang N, Yacoubian S, Lee CH, Yang R, Petasis NA, Serhan CN. Resolvin D1 binds human phagocytes with evidence for proresolving receptors. Proceedings of the National Academy of Sciences of the United States of America. 107: 1660-5. PMID 20080636 DOI: 10.1073/Pnas.0907342107  0.617
2010 Marcheselli VL, Mukherjee PK, Arita M, Hong S, Antony R, Sheets K, Winkler JW, Petasis NA, Serhan CN, Bazan NG. Neuroprotectin D1/protectin D1 stereoselective and specific binding with human retinal pigment epithelial cells and neutrophils. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 82: 27-34. PMID 19931440 DOI: 10.1016/J.Plefa.2009.10.010  0.795
2010 Ohira T, Arita M, Omori K, Recchiuti A, Van Dyke TE, Serhan CN. Resolvin E1 receptor activation signals phosphorylation and phagocytosis. The Journal of Biological Chemistry. 285: 3451-61. PMID 19906641 DOI: 10.1074/Jbc.M109.044131  0.39
2010 Gleissman H, Yang R, Martinod K, Lindskog M, Serhan CN, Johnsen JI, Kogner P. Docosahexaenoic acid metabolome in neural tumors: identification of cytotoxic intermediates. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 906-15. PMID 19890019 DOI: 10.1096/Fj.09-137919  0.394
2010 Ishida T, Yoshida M, Arita M, Nishitani Y, Nishiumi S, Masuda A, Mizuno S, Takagawa T, Morita Y, Kutsumi H, Inokuchi H, Serhan CN, Blumberg RS, Azuma T. Resolvin E1, an endogenous lipid mediator derived from eicosapentaenoic acid, prevents dextran sulfate sodium-induced colitis. Inflammatory Bowel Diseases. 16: 87-95. PMID 19572372 DOI: 10.1002/Ibd.21029  0.473
2010 Bannenberg G, Serhan CN. A Novel Genus of Specialized Anti-Inflammatory and Pro-Resolution Lipid Mediators Neuroimmune Biology. 9: 37-57. DOI: 10.1016/S1567-7443(10)70009-0  0.382
2010 Serhan CN. Lipoxins and aspirin-triggered 15-epi-lipoxins. pro-resolving mediators in anti-inflammation and resolution Handbook of Cell Signaling, 2/E. 2: 1235-1242. DOI: 10.1016/B978-0-12-374145-5.00152-2  0.321
2009 Spite M, Norling LV, Summers L, Yang R, Cooper D, Petasis NA, Flower RJ, Perretti M, Serhan CN. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis Nature. 461: 1287-1291. PMID 19865173 DOI: 10.1038/Nature08541  0.666
2009 Sun YP, Tjonahen E, Keledjian R, Zhu M, Yang R, Recchiuti A, Pillai PS, Petasis NA, Serhan CN. Anti-inflammatory and pro-resolving properties of benzo-lipoxin A4 analogs Prostaglandins Leukotrienes and Essential Fatty Acids. 81: 357-366. PMID 19853429 DOI: 10.1016/J.Plefa.2009.09.004  0.64
2009 Serhan CN. Systems approach to inflammation resolution: Identification of novel anti-inflammatory and pro-resolving mediators Journal of Thrombosis and Haemostasis. 7: 44-48. PMID 19630766 DOI: 10.1111/J.1538-7836.2009.03396.X  0.445
2009 Ye RD, Boulay F, Wang JM, Dahlgren C, Gerard C, Parmentier M, Serhan CN, Murphy PM. International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) family. Pharmacological Reviews. 61: 119-61. PMID 19498085 DOI: 10.1124/Pr.109.001578  0.317
2009 El Kebir D, József L, Pan W, Wang L, Petasis NA, Serhan CN, Filep JG. 15-epi-lipoxin A4 inhibits myeloperoxidase signaling and enhances resolution of acute lung injury American Journal of Respiratory and Critical Care Medicine. 180: 311-319. PMID 19483113 DOI: 10.1164/Rccm.200810-1601Oc  0.625
2009 Spite M, Summers L, Porter TF, Srivastava S, Bhatnagar A, Serhan CN. Resolvin D1 controls inflammation initiated by glutathione-lipid conjugates formed during oxidative stress. British Journal of Pharmacology. 158: 1062-73. PMID 19422383 DOI: 10.1111/J.1476-5381.2009.00234.X  0.426
2009 Jin Y, Arita M, Zhang Q, Saban DR, Chauhan SK, Chiang N, Serhan CN, Dana R. Anti-angiogenesis effect of the novel anti-inflammatory and pro-resolving lipid mediators. Investigative Ophthalmology & Visual Science. 50: 4743-52. PMID 19407006 DOI: 10.1167/Iovs.08-2462  0.411
2009 Zurier RB, Sun YP, George KL, Stebulis JA, Rossetti RG, Skulas A, Judge E, Serhan CN. Ajulemic acid, a synthetic cannabinoid, increases formation of the endogenous proresolving and anti-inflammatory eicosanoid, lipoxin A4. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 1503-9. PMID 19124557 DOI: 10.1096/Fj.08-118323  0.472
2009 Serhan CN, Yang R, Martinod K, Kasuga K, Pillai PS, Porter TF, Oh SF, Spite M. Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions. The Journal of Experimental Medicine. 206: 15-23. PMID 19103881 DOI: 10.1084/Jem.20081880  0.613
2008 Kasuga K, Yang R, Porter TF, Agrawal N, Petasis NA, Irimia D, Toner M, Serhan CN. Rapid appearance of resolvin precursors in inflammatory exudates: Novel mechanisms in resolution Journal of Immunology. 181: 8677-8687. PMID 19050288 DOI: 10.4049/Jimmunol.181.12.8677  0.655
2008 Serhan CN. Systems approach with inflammatory exudates uncovers novel anti-inflammatory and pro-resolving mediators Prostaglandins Leukotrienes and Essential Fatty Acids. 79: 157-163. PMID 19008087 DOI: 10.1016/J.Plefa.2008.09.012  0.439
2008 Malawista SE, Chevance AdB, Damme JV, Serhan CN. Tonic inhibition of chemotaxis in human plasma Proceedings of the National Academy of Sciences of the United States of America. 105: 17949-17954. PMID 18997012 DOI: 10.1073/Pnas.0802572105  0.334
2008 Chen M, Divangahi M, Gan H, Shin DS, Hong S, Lee DM, Serhan CN, Behar SM, Remold HG. Lipid mediators in innate immunity against tuberculosis: opposing roles of PGE2 and LXA4 in the induction of macrophage death. The Journal of Experimental Medicine. 205: 2791-801. PMID 18955568 DOI: 10.1084/Jem.20080767  0.36
2008 Herrera BS, Ohira T, Gao L, Omori K, Yang R, Zhu M, Muscara MN, Serhan CN, Van Dyke TE, Gyurko R. An endogenous regulator of inflammation, resolvin E1, modulates osteoclast differentiation and bone resorption. British Journal of Pharmacology. 155: 1214-23. PMID 18806821 DOI: 10.1038/Bjp.2008.367  0.311
2008 Serhan CN. Controlling the resolution of acute inflammation: A new genus of dual anti-inflammatory and proresolving mediators Journal of Periodontology. 79: 1520-1526. PMID 18673006 DOI: 10.1902/Jop.2008.080231  0.452
2008 Haworth O, Cernadas M, Yang R, Serhan CN, Levy BD. Resolvin E1 regulates interleukin 23, interferon-gamma and lipoxin A4 to promote the resolution of allergic airway inflammation. Nature Immunology. 9: 873-9. PMID 18568027 DOI: 10.1038/Ni.1627  0.327
2008 Merched AJ, Ko K, Gotlinger KH, Serhan CN, Chan L. Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3595-606. PMID 18559988 DOI: 10.1096/Fj.08-112201  0.45
2008 Dona M, Fredman G, Schwab JM, Chiang N, Arita M, Goodarzi A, Cheng G, von Andrian UH, Serhan CN. Resolvin E1, an EPA-derived mediator in whole blood, selectively counterregulates leukocytes and platelets. Blood. 112: 848-55. PMID 18480426 DOI: 10.1182/Blood-2007-11-122598  0.393
2008 Serhan CN, Chiang N, Van Dyke TE. Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Nature Reviews. Immunology. 8: 349-61. PMID 18437155 DOI: 10.1038/Nri2294  0.436
2008 Poulsen RC, Gotlinger KH, Serhan CN, Kruger MC. Identification of inflammatory and proresolving lipid mediators in bone marrow and their lipidomic profiles with ovariectomy and omega-3 intake. American Journal of Hematology. 83: 437-45. PMID 18429055 DOI: 10.1002/Ajh.21170  0.35
2008 Machado FS, Esper L, Dias A, Madan R, Gu Y, Hildeman D, Serhan CN, Karp CL, Aliberti J. Native and aspirin-triggered lipoxins control innate immunity by inducing proteasomal degradation of TRAF6. The Journal of Experimental Medicine. 205: 1077-86. PMID 18411340 DOI: 10.1084/Jem.20072416  0.348
2008 Chiang N, Schwab JM, Fredman G, Kasuga K, Gelman S, Serhan CN. Anesthetics impact the resolution of inflammation. Plos One. 3: e1879. PMID 18382663 DOI: 10.1371/Journal.Pone.0001879  0.428
2008 Hong S, Porter TF, Lu Y, Oh SF, Pillai PS, Serhan CN. Resolvin E1 metabolome in local inactivation during inflammation-resolution. Journal of Immunology (Baltimore, Md. : 1950). 180: 3512-9. PMID 18292578 DOI: 10.4049/Jimmunol.180.5.3512  0.615
2008 Petasis NA, Keledjian R, Sun YP, Nagulapalli KC, Tjonahen E, Yang R, Serhan CN. Design and synthesis of benzo-lipoxin A4 analogs with enhanced stability and potent anti-inflammatory properties Bioorganic and Medicinal Chemistry Letters. 18: 1382-1387. PMID 18249111 DOI: 10.1016/J.Bmcl.2008.01.013  0.616
2008 Serhan CN, Yacoubian S, Yang R. Anti-inflammatory and proresolving lipid mediators Annual Review of Pathology: Mechanisms of Disease. 3: 279-312. PMID 18233953 DOI: 10.1146/Annurev.Pathmechdis.3.121806.151409  0.449
2008 Masoodi M, Mir AA, Petasis NA, Serhan CN, Nicolaou A. Simultaneous lipidomic analysis of three families of bioactive lipid mediators leukotrienes, resolvins, protectins and related hydroxy-fatty acids by liquid chromatography/electrospray ionisation tandem mass spectrometry Rapid Communications in Mass Spectrometry. 22: 75-83. PMID 18059001 DOI: 10.1002/Rcm.3331  0.576
2008 Serhan CN, Chiang N. Endogenous pro-resolving and anti-inflammatory lipid mediators: a new pharmacologic genus. British Journal of Pharmacology. 153: S200-15. PMID 17965751 DOI: 10.1038/Sj.Bjp.0707489  0.477
2008 Ishida T, Yoshida M, Nishitani Y, Kure I, Shiomi Y, Arita M, Serhan CN, Azuma T. S1747 Rsolvin E1, An Endogenous Lipid Mediator Derived from Eicosapentaenoic Acid Protects in Dextran Sulfate Sodium Induced Colitis Gastroenterology. 134: A-262. DOI: 10.1016/S0016-5085(08)61218-4  0.383
2007 Haas-Stapleton EJ, Lu Y, Hong S, Arita M, Favoreto S, Nigam S, Serhan CN, Agabian N. Candida albicans modulates host defense by biosynthesizing the pro-resolving mediator resolvin E1. Plos One. 2: e1316. PMID 18091990 DOI: 10.1371/Journal.Pone.0001316  0.427
2007 Hasturk H, Kantarci A, Goguet-Surmenian E, Blackwood A, Andry C, Serhan CN, Van Dyke TE. Resolvin E1 regulates inflammation at the cellular and tissue level and restores tissue homeostasis in vivo. Journal of Immunology (Baltimore, Md. : 1950). 179: 7021-9. PMID 17982093 DOI: 10.4049/Jimmunol.179.10.7021  0.428
2007 Yacoubian S, Serhan CN. New endogenous anti-inflammatory and proresolving lipid mediators: Implications for rheumatic diseases Nature Clinical Practice Rheumatology. 3: 570-579. PMID 17906612 DOI: 10.1038/Ncprheum0616  0.462
2007 Bannenberg G, Arita M, Serhan CN. Endogenous receptor agonists: resolving inflammation. Thescientificworldjournal. 7: 1440-62. PMID 17767360 DOI: 10.1100/Tsw.2007.188  0.439
2007 Levy BD, Lukacs NW, Berlin AA, Schmidt B, Guilford WJ, Serhan CN, Parkinson JF. Lipoxin A4 stable analogs reduce allergic airway responses via mechanisms distinct from CysLT1 receptor antagonism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 3877-84. PMID 17625069 DOI: 10.1096/Fj.07-8653Com  0.374
2007 Connor KM, SanGiovanni JP, Lofqvist C, Aderman CM, Chen J, Higuchi A, Hong S, Pravda EA, Majchrzak S, Carper D, Hellstrom A, Kang JX, Chew EY, Salem N, Serhan CN, et al. Increased dietary intake of omega-3-polyunsaturated fatty acids reduces pathological retinal angiogenesis. Nature Medicine. 13: 868-73. PMID 17589522 DOI: 10.1038/Nm1591  0.337
2007 El Kebir D, József L, Khreiss T, Pan W, Petasis NA, Serhan CN, Filep JG. Aspirin-triggered lipoxins override the apoptosis-delaying action of serum amyloid A in human neutrophils: A novel mechanism for resolution of inflammation Journal of Immunology. 179: 616-622. PMID 17579083 DOI: 10.4049/Jimmunol.179.1.616  0.619
2007 Schwab JM, Chiang N, Arita M, Serhan CN. Resolvin E1 and protectin D1 activate inflammation-resolution programmes. Nature. 447: 869-74. PMID 17568749 DOI: 10.1038/Nature05877  0.4
2007 Campbell EL, Louis NA, Tomassetti SE, Canny GO, Arita M, Serhan CN, Colgan SP. Resolvin E1 promotes mucosal surface clearance of neutrophils: a new paradigm for inflammatory resolution. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 3162-70. PMID 17496159 DOI: 10.1096/Fj.07-8473Com  0.609
2007 Arita M, Ohira T, Sun YP, Elangovan S, Chiang N, Serhan CN. Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation. Journal of Immunology (Baltimore, Md. : 1950). 178: 3912-7. PMID 17339491 DOI: 10.4049/Jimmunol.178.6.3912  0.456
2007 Ariel A, Serhan CN. Resolvins and protectins in the termination program of acute inflammation Trends in Immunology. 28: 176-183. PMID 17337246 DOI: 10.1016/J.It.2007.02.007  0.441
2007 Serhan CN, Brain SD, Buckley CD, Gilroy DW, Haslett C, O'Neill LA, Perretti M, Rossi AG, Wallace JL. Resolution of inflammation: state of the art, definitions and terms. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 325-32. PMID 17267386 DOI: 10.1096/Fj.06-7227Rev  0.43
2007 Sun YP, Oh SF, Uddin J, Yang R, Gotlinger K, Campbell E, Colgan SP, Petasis NA, Serhan CN. Resolvin D1 and its aspirin-triggered 17R epimer: Stereochemical assignments, anti-inflammatory properties, and enzymatic inactivation Journal of Biological Chemistry. 282: 9323-9334. PMID 17244615 DOI: 10.1074/Jbc.M609212200  0.778
2007 Svensson CI, Zattoni M, Serhan CN. Lipoxins and aspirin-triggered lipoxin inhibit inflammatory pain processing. The Journal of Experimental Medicine. 204: 245-52. PMID 17242163 DOI: 10.1084/Jem.20061826  0.314
2007 Levy BD, Kohli P, Gotlinger K, Haworth O, Hong S, Kazani S, Israel E, Haley KJ, Serhan CN. Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness. Journal of Immunology (Baltimore, Md. : 1950). 178: 496-502. PMID 17182589 DOI: 10.4049/Jimmunol.178.1.496  0.338
2007 Lu Y, Hong S, Yang R, Uddin J, Gotlinger KH, Petasis NA, Serhan CN. Identification of endogenous resolvin E1 and other lipid mediators derived from eicosapentaenoic acid via electrospray low-energy tandem mass spectrometry: Spectra and fragmentation mechanisms Rapid Communications in Mass Spectrometry. 21: 7-22. PMID 17131464 DOI: 10.1002/Rcm.2798  0.564
2007 Serhan CN. Resolution phase of inflammation: Novel endogenous anti-inflammatory and proresolving lipid mediators and pathways Annual Review of Immunology. 25: 101-137. PMID 17090225 DOI: 10.1146/Annurev.Immunol.25.022106.141647  0.442
2007 Hong S, Lu Y, Yang R, Gotlinger KH, Petasis NA, Serhan CN. Resolvin D1, Protectin D1, and Related Docosahexaenoic Acid-Derived Products: Analysis via Electrospray/Low Energy Tandem Mass Spectrometry Based on Spectra and Fragmentation Mechanisms Journal of the American Society For Mass Spectrometry. 18: 128-144. PMID 17055291 DOI: 10.1016/J.Jasms.2006.09.002  0.553
2007 Serhan CN, Lu Y, Hong S, Yang R. Mediator Lipidomics: Search Algorithms for Eicosanoids, Resolvins, and Protectins Methods in Enzymology. 432: 275-317. DOI: 10.1016/S0076-6879(07)32012-0  0.385
2006 Chiang N, Serhan CN. New mechanism for an old drug: aspirin triggers anti-inflammatory lipid mediators with gender implications. Comprehensive Therapy. 32: 150-7. PMID 17435267 DOI: 10.1007/S12019-006-0005-6  0.368
2006 Tjonahen E, Oh SF, Siegelman J, Elangovan S, Percarpio KB, Hong S, Arita M, Serhan CN. Resolvin E2: identification and anti-inflammatory actions: pivotal role of human 5-lipoxygenase in resolvin E series biosynthesis. Chemistry & Biology. 13: 1193-202. PMID 17114001 DOI: 10.1016/J.Chembiol.2006.09.011  0.638
2006 Duffield JS, Hong S, Vaidya VS, Lu Y, Fredman G, Serhan CN, Bonventre JV. Resolvin D series and protectin D1 mitigate acute kidney injury. Journal of Immunology (Baltimore, Md. : 1950). 177: 5902-11. PMID 17056514 DOI: 10.4049/Jimmunol.177.9.5902  0.355
2006 Ariel A, Fredman G, Sun YP, Kantarci A, Van Dyke TE, Luster AD, Serhan CN. Apoptotic neutrophils and T cells sequester chemokines during immune response resolution through modulation of CCR5 expression. Nature Immunology. 7: 1209-16. PMID 17013391 DOI: 10.1038/Ni1392  0.43
2006 Chiang N, Serhan CN, Dahlén SE, Drazen JM, Hay DW, Rovati GE, Shimizu T, Yokomizo T, Brink C. The lipoxin receptor ALX: potent ligand-specific and stereoselective actions in vivo. Pharmacological Reviews. 58: 463-87. PMID 16968948 DOI: 10.1124/Pr.58.3.4  0.37
2006 Wada K, Arita M, Nakajima A, Katayama K, Kudo C, Kamisaki Y, Serhan CN. Leukotriene B4 and lipoxin A4 are regulatory signals for neural stem cell proliferation and differentiation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1785-92. PMID 16940150 DOI: 10.1096/Fj.06-5809Com  0.332
2006 Serhan CN. Novel Chemical Mediators in the Resolution of Inflammation: Resolvins and Protectins Anesthesiology Clinics of North America. 24: 341-364. PMID 16927933 DOI: 10.1016/J.Atc.2006.01.003  0.437
2006 Xia S, Lu Y, Wang J, He C, Hong S, Serhan CN, Kang JX. Melanoma growth is reduced in fat-1 transgenic mice: impact of omega-6/omega-3 essential fatty acids. Proceedings of the National Academy of Sciences of the United States of America. 103: 12499-504. PMID 16888035 DOI: 10.1073/Pnas.0605394103  0.319
2006 Hudert CA, Weylandt KH, Lu Y, Wang J, Hong S, Dignass A, Serhan CN, Kang JX. Transgenic mice rich in endogenous omega-3 fatty acids are protected from colitis. Proceedings of the National Academy of Sciences of the United States of America. 103: 11276-81. PMID 16847262 DOI: 10.1073/Pnas.0601280103  0.349
2006 Chiang N, Serhan CN. Cell-cell interaction in the transcellular biosynthesis of novel omega-3-derived lipid mediators. Methods in Molecular Biology (Clifton, N.J.). 341: 227-50. PMID 16799203 DOI: 10.1385/1-59745-113-4:227  0.458
2006 Serhan CN, Hong S, Lu Y. Lipid mediator informatics-lipidomics: Novel pathways in mapping resolution Aaps Journal. 8. PMID 16796379 DOI: 10.1007/Bf02854899  0.328
2006 Liu W, Cao D, Oh SF, Serhan CN, Kulmacz RJ. Divergent cyclooxygenase responses to fatty acid structure and peroxide level in fish and mammalian prostaglandin H synthases. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1097-108. PMID 16770009 DOI: 10.1096/Fj.05-5273Com  0.555
2006 Arita M, Oh SF, Chonan T, Hong S, Elangovan S, Sun YP, Uddin J, Petasis NA, Serhan CN. Metabolic inactivation of resolvin E1 and stabilization of its anti-inflammatory actions Journal of Biological Chemistry. 281: 22847-22854. PMID 16757471 DOI: 10.1074/Jbc.M603766200  0.734
2006 Lu Y, Hong S, Gotlinger K, Serhan CN. Lipid mediator informatics and proteomics in inflammation resolution. Thescientificworldjournal. 6: 589-614. PMID 16752008 DOI: 10.1100/Tsw.2006.118  0.322
2006 Schwab JM, Serhan CN. Lipoxins and new lipid mediators in the resolution of inflammation Current Opinion in Pharmacology. 6: 414-420. PMID 16750421 DOI: 10.1016/J.Coph.2006.02.006  0.462
2006 Serhan CN, Gotlinger K, Hong S, Lu Y, Siegelman J, Baer T, Yang R, Colgan SP, Petasis NA. Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes. Journal of Immunology (Baltimore, Md. : 1950). 176: 1848-59. PMID 16424216 DOI: 10.4049/Jimmunol.176.3.1848  0.698
2006 Machado FS, Johndrow JE, Esper L, Dias A, Bafica A, Serhan CN, Aliberti J. Anti-inflammatory actions of lipoxin A4 and aspirin-triggered lipoxin are SOCS-2 dependent Nature Medicine. 12: 330-334. PMID 16415877 DOI: 10.1038/Nm1355  0.418
2006 Hasturk H, Kantarci A, Ohira T, Arita M, Ebrahimi N, Chiang N, Petasis NA, Levy BD, Serhan CN, Van Dyke TE. RvE1 protects from local inflammation and osteoclast- mediated bone destruction in periodontitis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 401-3. PMID 16373400 DOI: 10.1096/Fj.05-4724Fje  0.639
2006 Serhan CN, Chiang N. Putting the brakes on neutrophils Blood. 107: 1742-1743. DOI: 10.1182/Blood-2005-12-4936  0.37
2006 Serhan CN. Resolvins and protectins: Novel lipid mediators in anti-inflammation and resolution Scandinavian Journal of Food and Nutrition. 50: 68-78. DOI: 10.1080/17482970601066298  0.354
2006 Serhan CN, Ariel A, Fredman G, Sun Y, Kantarci A, Dyke TEV, Luster AD. Removal of CCR5 ligands and induction of pro-resolving lipid mediators by apoptotic neutrophils during resolution Nature Protocols. DOI: 10.1038/Nprot.2006.295  0.345
2005 Serhan CN, Savill J. Resolution of inflammation: The beginning programs the end Nature Immunology. 6: 1191-1197. PMID 16369558 DOI: 10.1038/Ni1276  0.419
2005 Hong S, Tjonahen E, Morgan EL, Lu Y, Serhan CN, Rowley AF. Rainbow trout (Oncorhynchus mykiss) brain cells biosynthesize novel docosahexaenoic acid-derived resolvins and protectins-Mediator lipidomic analysis. Prostaglandins & Other Lipid Mediators. 78: 107-16. PMID 16303609 DOI: 10.1016/J.Prostaglandins.2005.04.004  0.385
2005 Ariel A, Li PL, Wang W, Tang WX, Fredman G, Hong S, Gotlinger KH, Serhan CN. The docosatriene protectin D1 is produced by TH2 skewing and promotes human T cell apoptosis via lipid raft clustering. The Journal of Biological Chemistry. 280: 43079-86. PMID 16216871 DOI: 10.1074/Jbc.M509796200  0.413
2005 Lukiw WJ, Cui JG, Marcheselli VL, Bodker M, Botkjaer A, Gotlinger K, Serhan CN, Bazan NG. A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease. The Journal of Clinical Investigation. 115: 2774-83. PMID 16151530 DOI: 10.1172/Jci25420  0.325
2005 Chiang N, Arita M, Serhan CN. Anti-inflammatory circuitry: lipoxin, aspirin-triggered lipoxins and their receptor ALX. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 73: 163-77. PMID 16125378 DOI: 10.1016/J.Plefa.2005.05.003  0.433
2005 Arita M, Clish CB, Serhan CN. The contributions of aspirin and microbial oxygenase to the biosynthesis of anti-inflammatory resolvins: Novel oxygenase products from ω-3 polyunsaturated fatty acids Biochemical and Biophysical Research Communications. 338: 149-157. PMID 16112645 DOI: 10.1016/J.Bbrc.2005.07.181  0.461
2005 Petasis NA, Akritopoulou-Zanze I, Fokin VV, Bernasconi G, Keledjian R, Yang R, Uddin J, Nagulapalli KC, Serhan CN. Design, synthesis and bioactions of novel stable mimetics of lipoxins and aspirin-triggered lipoxins. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 73: 301-21. PMID 16098719 DOI: 10.1016/J.Plefa.2005.05.020  0.644
2005 Levy BD, Hickey L, Morris AJ, Larvie M, Keledjian R, Petasis NA, Bannenberg G, Serhan CN. Novel polyisoprenyl phosphates block phospholipase D and human neutrophil activation in vitro and murine peritoneal inflammation in vivo. British Journal of Pharmacology. 146: 344-51. PMID 16041402 DOI: 10.1038/Sj.Bjp.0706338  0.648
2005 Serhan CN. Lipoxins and aspirin-triggered 15-epi-lipoxins are the first lipid mediators of endogenous anti-inflammation and resolution Prostaglandins Leukotrienes and Essential Fatty Acids. 73: 141-162. PMID 16005201 DOI: 10.1016/J.Plefa.2005.05.002  0.442
2005 Arita M, Yoshida M, Hong S, Tjonahen E, Glickman JN, Petasis NA, Blumberg RS, Serhan CN. Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis Proceedings of the National Academy of Sciences of the United States of America. 102: 7671-7676. PMID 15890784 DOI: 10.1073/Pnas.0409271102  0.65
2005 Yarovinsky F, Zhang D, Andersen JF, Bannenberg GL, Serhan CN, Hayden MS, Hieny S, Sutterwala FS, Flavell RA, Ghosh S, Sher A. TLR11 activation of dendritic cells by a protozoan profilin-like protein. Science (New York, N.Y.). 308: 1626-9. PMID 15860593 DOI: 10.1126/Science.1109893  0.303
2005 Bannenberg GL, Chiang N, Ariel A, Arita M, Tjonahen E, Gotlinger KH, Hong S, Serhan CN. Molecular circuits of resolution: formation and actions of resolvins and protectins. Journal of Immunology (Baltimore, Md. : 1950). 174: 4345-55. PMID 15778399 DOI: 10.4049/Jimmunol.174.7.4345  0.427
2005 Arita M, Bianchini F, Aliberti J, Sher A, Chiang N, Hong S, Yang R, Petasis NA, Serhan CN. Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1. The Journal of Experimental Medicine. 201: 713-22. PMID 15753205 DOI: 10.1084/Jem.20042031  0.631
2005 Serhan CN. Novel eicosanoid and docosanoid mediators: Resolvins, docosatrienes, and neuroprotectins Current Opinion in Clinical Nutrition and Metabolic Care. 8: 115-121. PMID 15716788 DOI: 10.1097/00075197-200503000-00003  0.467
2005 Devchand PR, Schmidt BA, Primo VC, Zhang QY, Arnaout MA, Serhan CN, Nikolic B. A synthetic eicosanoid LX-mimetic unravels host-donor interactions in allogeneic BMT-induced GvHD to reveal an early protective role for host neutrophils. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 203-10. PMID 15677343 DOI: 10.1096/Fj.04-2565Com  0.326
2005 Serhan CN. Novel omega -- 3-derived local mediators in anti-inflammation and resolution. Pharmacology & Therapeutics. 105: 7-21. PMID 15626453 DOI: 10.1016/J.Pharmthera.2004.09.002  0.472
2004 Chiang N, Serhan CN. Aspirin triggers formation of anti-inflammatory mediators: New mechanism for an old drug. Discovery Medicine. 4: 470-5. PMID 20704950  0.306
2004 Serhan CN, Arita M, Hong S, Gotlinger K. Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their endogenous aspirin-triggered epimers Lipids. 39: 1125-1132. PMID 15726828 DOI: 10.1007/S11745-004-1339-7  0.437
2004 Serhan CN. Clues for new therapeutics in osteoporosis and periodontal disease: New roles for lipoxygenases? Expert Opinion On Therapeutic Targets. 8: 643-652. PMID 15584868 DOI: 10.1517/14728222.8.6.643  0.364
2004 Chiang N, Bermudez EA, Ridker PM, Hurwitz S, Serhan CN. Aspirin triggers antiinflammatory 15-epi-lipoxin A4 and inhibits thromboxane in a randomized human trial. Proceedings of the National Academy of Sciences of the United States of America. 101: 15178-83. PMID 15471991 DOI: 10.1073/Pnas.0405445101  0.316
2004 Serhan CN. A search for endogenous mechanisms of anti-inflammation uncovers novel chemical mediators: Missing links to resolution Histochemistry and Cell Biology. 122: 305-321. PMID 15322859 DOI: 10.1007/S00418-004-0695-8  0.462
2004 Andersson P, Serhan CN, Petasis NA, Palmblad J. Interactions between lipoxin A4, the stable analogue 16-phenoxy-lipoxin A4 and leukotriene B4 in cytokine generation by human monocytes Scandinavian Journal of Immunology. 60: 249-256. PMID 15320881 DOI: 10.1111/J.0300-9475.2004.01469.X  0.543
2004 Bannenberg G, Moussignac RL, Gronert K, Devchand PR, Schmidt BA, Guilford WJ, Bauman JG, Subramanyam B, Perez HD, Parkinson JF, Serhan CN. Lipoxins and novel 15-epi-lipoxin analogs display potent anti-inflammatory actions after oral administration. British Journal of Pharmacology. 143: 43-52. PMID 15302682 DOI: 10.1038/Sj.Bjp.0705912  0.405
2004 Serhan CN, Gotlinger K, Hong S, Arita M. Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their aspirin-triggered endogenous epimers: An overview of their protective roles in catabasis Prostaglandins and Other Lipid Mediators. 73: 155-172. PMID 15290791 DOI: 10.1016/J.Prostaglandins.2004.03.005  0.461
2004 Ohira T, Bannenberg G, Arita M, Takahashi M, Ge Q, Van Dyke TE, Stahl GL, Serhan CN, Badwey JA. A stable aspirin-triggered lipoxin A4 analog blocks phosphorylation of leukocyte-specific protein 1 in human neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 173: 2091-8. PMID 15265945 DOI: 10.4049/Jimmunol.173.3.2091  0.354
2004 Mukherjee PK, Marcheselli VL, Serhan CN, Bazan NG. Neuroprotectin D1: a docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress. Proceedings of the National Academy of Sciences of the United States of America. 101: 8491-6. PMID 15152078 DOI: 10.1073/Pnas.0402531101  0.353
2004 Serhan CN, Chiang N. Novel endogenous small molecules as the checkpoint controllers in inflammation and resolution: entrée for resoleomics. Rheumatic Diseases Clinics of North America. 30: 69-95. PMID 15061569 DOI: 10.1016/S0889-857X(03)00117-0  0.471
2004 Brink C, Dahlén SE, Drazen J, Evans JF, Hay DW, Rovati GE, Serhan CN, Shimizu T, Yokomizo T. International Union of Pharmacology XLIV. Nomenclature for the oxoeicosanoid receptor. Pharmacological Reviews. 56: 149-57. PMID 15001665 DOI: 10.1124/Pr.56.1.4  0.316
2004 Bannenberg GL, Aliberti J, Hong S, Sher A, Serhan C. Exogenous pathogen and plant 15-lipoxygenase initiate endogenous lipoxin A4 biosynthesis. The Journal of Experimental Medicine. 199: 515-23. PMID 14970178 DOI: 10.1084/Jem.20031325  0.339
2004 Vance RE, Hong S, Gronert K, Serhan CN, Mekalanos JJ. The opportunistic pathogen Pseudomonas aeruginosa carries a secretable arachidonate 15-lipoxygenase. Proceedings of the National Academy of Sciences of the United States of America. 101: 2135-9. PMID 14766977 DOI: 10.1073/Pnas.0307308101  0.386
2004 Gronert K, Kantarci A, Levy BD, Clish CB, Odparlik S, Hasturk H, Badwey JA, Colgan SP, Van Dyke TE, Serhan CN. A molecular defect in intracellular lipid signaling in human neutrophils in localized aggressive periodontal tissue damage. Journal of Immunology (Baltimore, Md. : 1950). 172: 1856-61. PMID 14734770 DOI: 10.4049/Jimmunol.172.3.1856  0.582
2003 Serhan CN, Jain A, Marleau S, Clish C, Kantarci A, Behbehani B, Colgan SP, Stahl GL, Merched A, Petasis NA, Chan L, Van Dyke TE. Reduced Inflammation and Tissue Damage in Transgenic Rabbits Overexpressing 15-Lipoxygenase and Endogenous Anti-inflammatory Lipid Mediators Journal of Immunology. 171: 6856-6865. PMID 14662892 DOI: 10.4049/Jimmunol.171.12.6856  0.739
2003 Schwab JM, Schluesener HJ, Meyermann R, Serhan CN. COX-3 the enzyme and the concept: Steps towards highly specialized pathways and precision therapeutics? Prostaglandins Leukotrienes and Essential Fatty Acids. 69: 339-343. PMID 14580368 DOI: 10.1016/J.Plefa.2003.07.003  0.359
2003 Jain A, Batista EL, Serhan C, Stahl GL, Van Dyke TE. Role for periodontitis in the progression of lipid deposition in an animal model. Infection and Immunity. 71: 6012-8. PMID 14500522 DOI: 10.1128/Iai.71.10.6012-6018.2003  0.316
2003 Serhan CN, Levy B. Novel Pathways and Endogenous Mediators in Anti-Inflammation and Resolution Chemical Immunology and Allergy. 83: 115-145. PMID 12947982 DOI: 10.1159/000071558  0.393
2003 Marcheselli VL, Hong S, Lukiw WJ, Tian XH, Gronert K, Musto A, Hardy M, Gimenez JM, Chiang N, Serhan CN, Bazan NG. Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression. The Journal of Biological Chemistry. 278: 43807-17. PMID 12923200 DOI: 10.1074/Jbc.M305841200  0.378
2003 Levy O, Canny G, Serhan CN, Colgan SP. Expression of BPI (bactericidal/permeability-increasing protein) in human mucosal epithelia. Biochemical Society Transactions. 31: 795-800. PMID 12887308 DOI: 10.1042/Bst0310795  0.367
2003 Levy BD, Serhan CN. Exploring new approaches to the treatment of asthma: Potential roles for lipoxins and aspirin-triggered lipid mediators Drugs of Today. 39: 373-384. PMID 12861350 DOI: 10.1358/Dot.2003.39.5.740217  0.364
2003 Serhan CN, Levy B. Success of prostaglandin E2 in structure-function is a challenge for structure-based therapeutics Proceedings of the National Academy of Sciences of the United States of America. 100: 8609-8611. PMID 12861081 DOI: 10.1073/Pnas.1733589100  0.423
2003 Ariel A, Chiang N, Arita M, Petasis NA, Serhan CN. Aspirin-triggered lipoxin A4 and B4 analogs block extracellular signal-regulated kinase-dependent TNF-alpha secretion from human T cells. Journal of Immunology (Baltimore, Md. : 1950). 170: 6266-72. PMID 12794159 DOI: 10.4049/Jimmunol.170.12.6266  0.61
2003 Levy BD, De Sanctis GT, Devchand PR, Kim E, Ackerman K, Schmidt B, Szczeklik W, Drazen JM, Serhan CN. Lipoxins and aspirin-triggered lipoxins in airway responses. Advances in Experimental Medicine and Biology. 525: 19-23. PMID 12751730 DOI: 10.1007/978-1-4419-9194-2_5  0.346
2003 Chiang N, Takano T, Arita M, Watanabe S, Serhan CN. A novel rat lipoxin A4 receptor that is conserved in structure and function. British Journal of Pharmacology. 139: 89-98. PMID 12746227 DOI: 10.1038/Sj.Bjp.0705220  0.365
2003 Devchand PR, Arita M, Hong S, Bannenberg G, Moussignac RL, Gronert K, Serhan CN. Human ALX receptor regulates neutrophil recruitment in transgenic mice: roles in inflammation and host defense. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 652-9. PMID 12665478 DOI: 10.1096/Fj.02-0770Com  0.387
2003 Fierro IM, Colgan SP, Bernasconi G, Petasis NA, Clish CB, Arita M, Serhan CN. Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 inhibit human neutrophil migration: Comparisons between synthetic 15 epimers in chemotaxis and transmigration with microvessel endothelial cells and epithelial cells Journal of Immunology. 170: 2688-2694. PMID 12594298 DOI: 10.4049/Jimmunol.170.5.2688  0.727
2003 Hong S, Gronert K, Devchand PR, Moussignac RL, Serhan CN. Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation. The Journal of Biological Chemistry. 278: 14677-87. PMID 12590139 DOI: 10.1074/Jbc.M300218200  0.424
2003 Van Dyke TE, Serhan CN. Resolution of inflammation: A new paradigm for the pathogenesis of periodontal diseases Journal of Dental Research. 82: 82-90. PMID 12562878 DOI: 10.1177/154405910308200202  0.395
2002 Serhan CN, Chiang N. Lipid-derived mediators in endogenous anti-inflammation and resolution: lipoxins and aspirin-triggered 15-epi-lipoxins. Thescientificworldjournal. 2: 169-204. PMID 12806051 DOI: 10.1100/Tsw.2002.81  0.469
2002 Filep JG, Zouki C, Petasis NA, Hachicha M, Serhan CN. Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 modulate adhesion molecule expression on human leukocytes in whole blood and inhibit neutrophil-endothelial cell adhesion Advances in Experimental Medicine and Biology. 507: 223-228. PMID 12664589 DOI: 10.1007/978-1-4615-0193-0_34  0.657
2002 Bandeira-Melo C, Diaz BL, Cordeiro RS, Jose PJ, Serhan CN, Martins MA, Bozza PT. Inhibition of allergen-induced eosinophil migration by lipoxin (LX)A4 and aspirin-triggered 15-epi-LXA4. Advances in Experimental Medicine and Biology. 507: 211-6. PMID 12664587 DOI: 10.1007/978-1-4615-0193-0_32  0.357
2002 Titos E, Chiang N, Serhan CN, Romano M, Gaya J, Pueyo G, Clària J. Aspirin-triggered 15-epi-lipoxin A4 biosynthesis in rat liver cells. Advances in Experimental Medicine and Biology. 507: 199-209. PMID 12664586 DOI: 10.1007/978-1-4615-0193-0_31  0.446
2002 Serhan CN. Lipoxins and aspirin-triggered 15-epi-lipoxin biosynthesis: An update and role in anti-inflammation and pro-resolution Prostaglandins and Other Lipid Mediators. 68: 433-455. PMID 12432935 DOI: 10.1016/S0090-6980(02)00047-3  0.447
2002 Serhan CN, Hong S, Gronert K, Colgan SP, Devchand PR, Mirick G, Moussignac RL. Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. The Journal of Experimental Medicine. 196: 1025-37. PMID 12391014 DOI: 10.1084/Jem.20020760  0.633
2002 Perretti M, Chiang N, La M, Fierro IM, Marullo S, Getting SJ, Solito E, Serhan CN. Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor. Nature Medicine. 8: 1296-302. PMID 12368905 DOI: 10.1038/Nm786  0.412
2002 József L, Zouki C, Petasis NA, Serhan CN, Filep JG. Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 inhibit peroxynitrite formation, NF-κB and AP-1 activation, and IL-8 gene expression in human leukocytes Proceedings of the National Academy of Sciences of the United States of America. 99: 13266-13271. PMID 12235371 DOI: 10.1073/Pnas.202296999  0.602
2002 Levy BD, De Sanctis GT, Devchand PR, Kim E, Ackerman K, Schmidt BA, Szczeklik W, Drazen JM, Serhan CN. Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A(4). Nature Medicine. 8: 1018-23. PMID 12172542 DOI: 10.1038/Nm748  0.353
2002 Levy BD, Serhan CN. Polyisoprenyl phosphates: Natural antiinflammatory lipid signals Cellular and Molecular Life Sciences. 59: 729-741. PMID 12088274 DOI: 10.1007/S00018-002-8462-2  0.406
2002 Canny G, Levy O, Furuta GT, Narravula-Alipati S, Sisson RB, Serhan CN, Colgan SP. Lipid mediator-induced expression of bactericidal/ permeability-increasing protein (BPI) in human mucosal epithelia. Proceedings of the National Academy of Sciences of the United States of America. 99: 3902-7. PMID 11891303 DOI: 10.1073/Pnas.052533799  0.616
2002 Resnati M, Pallavicini I, Wang JM, Oppenheim J, Serhan CN, Romano M, Blasi F. The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R. Proceedings of the National Academy of Sciences of the United States of America. 99: 1359-64. PMID 11818541 DOI: 10.1073/Pnas.022652999  0.345
2002 Fierro IM, Kutok JL, Serhan CN. Novel lipid mediator regulators of endothelial cell proliferation and migration: Aspirin-triggered-15R-lipoxin A4 and lipoxin A4 Journal of Pharmacology and Experimental Therapeutics. 300: 385-392. PMID 11805195 DOI: 10.1124/Jpet.300.2.385  0.366
2002 ZHANG Y, WALKER JL, HUANG A, KEANEY JF, CLISH CB, SERHAN CN, LOSCALZO J. Expression of 5-lipoxygenase in pulmonary artery endothelial cells Biochemical Journal. 361: 267-276. DOI: 10.1042/Bj3610267  0.315
2001 Aliberti J, Hieny S, Reis e Sousa C, Serhan CN, Sher A. Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity. Nature Immunology. 3: 76-82. PMID 11743584 DOI: 10.1038/Ni745  0.32
2001 Clish CB, Sun YP, Serhan CN. Identification of dual cyclooxygenase-eicosanoid oxidoreductase inhibitors: NSAIDs that inhibit PG-LX reductase/LTB4 dehydrogenase Biochemical and Biophysical Research Communications. 288: 868-874. PMID 11688989 DOI: 10.1006/Bbrc.2001.5841  0.398
2001 Qiu FH, Devchand PR, Wada K, Serhan CN. Aspirin-triggered lipoxin A4 and lipoxin A4 up-regulate transcriptional corepressor NAB1 in human neutrophils The Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 2736-2738. PMID 11687510 DOI: 10.1096/Fj.01-0576Fje  0.39
2001 Levy BD, Clish CB, Schmidt B, Gronert K, Serhan CN. Lipid mediator class switching during acute inflammation: signals in resolution. Nature Immunology. 2: 612-9. PMID 11429545 DOI: 10.1038/89759  0.427
2001 Serhan CN, Oliw E. Unorthodox routes to prostanoid formation: New twists in cyclooxygenase-initiated pathways Journal of Clinical Investigation. 107: 1481-1489. PMID 11413151 DOI: 10.1172/Jci13375  0.423
2001 Fierro IM, Serhan CN. Mechanisms in anti-inflammation and resolution: The role of lipoxins and aspirin-triggered lipoxins Brazilian Journal of Medical and Biological Research. 34: 555-566. PMID 11323741 DOI: 10.1590/S0100-879X2001000500002  0.437
2001 Wada K, Qiu FH, Stahl GL, Serhan CN. Inosine monophosphate and aspirin-triggered 15-epi-lipoxin a4 act in concert to regulate neutrophil trafficking: Additive actions of two new endogenous anti-inflammatory mediators Journal of Hematotherapy and Stem Cell Research. 10: 75-79. PMID 11276361 DOI: 10.1089/152581601750098273  0.468
2001 Serhan CN, Fierro IM, Chiang N, Pouliot M. Cutting edge: nociceptin stimulates neutrophil chemotaxis and recruitment: inhibition by aspirin-triggered-15-epi-lipoxin A4. Journal of Immunology (Baltimore, Md. : 1950). 166: 3650-4. PMID 11238602 DOI: 10.4049/Jimmunol.166.6.3650  0.407
2001 Gronert K, Martinsson-Niskanen T, Ravasi S, Chiang N, Serhan CN. Selectivity of recombinant human leukotriene D(4), leukotriene B(4), and lipoxin A(4) receptors with aspirin-triggered 15-epi-LXA(4) and regulation of vascular and inflammatory responses. The American Journal of Pathology. 158: 3-9. PMID 11141472 DOI: 10.1016/S0002-9440(10)63937-5  0.317
2000 Serhan CN, Clish CB, Brannon J, Colgan SP, Chiang N, Gronert K. Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing. The Journal of Experimental Medicine. 192: 1197-204. PMID 11034610 DOI: 10.1084/Jem.192.8.1197  0.409
2000 Serhan CN, Clish CB. Aspirin triggered lipid mediators: Novel inhibitors of leucocyte trafficking Thorax. 55. PMID 10992546 DOI: 10.1136/Thorax.55.Suppl_2.S10  0.474
2000 Levy BD, Serhan CN. Polyisoprenyl phosphate signaling: Topography in human neutrophils Biochemical and Biophysical Research Communications. 275: 739-745. PMID 10973792 DOI: 10.1006/Bbrc.2000.3371  0.326
2000 Serhan CN, Levy BD, Clish CB, Gronert K, Chiang N. Lipoxins, aspirin-triggered 15-epi-lipoxin stable analogs and their receptors in anti-inflammation: a window for therapeutic opportunity. Ernst Schering Research Foundation Workshop. 143-85. PMID 10943332 DOI: 10.1007/978-3-662-04047-8_8  0.324
2000 Sanak M, Levy BD, Clish CB, Chiang N, Gronert K, Mastalerz L, Serhan CN, Szczeklik A. Aspirin-tolerant asthmatics generate more lipoxins than aspirin-intolerant asthmatics. The European Respiratory Journal. 16: 44-9. PMID 10933083 DOI: 10.1034/J.1399-3003.2000.16A08.X  0.391
2000 Clish CB, Levy BD, Chiang N, Tai HH, Serhan CN. Oxidoreductases in lipoxin A4 metabolic inactivation: a novel role for 15-onoprostaglandin 13-reductase/leukotriene B4 12-hydroxydehydrogenase in inflammation. The Journal of Biological Chemistry. 275: 25372-80. PMID 10837478 DOI: 10.1074/Jbc.M002863200  0.42
2000 Levy BD, Serhan CN. A novel polyisoprenyl phosphate signaling cascade in human neutrophils Annals of the New York Academy of Sciences. 905: 69-80. PMID 10818443 DOI: 10.1111/J.1749-6632.2000.Tb06539.X  0.41
2000 Pouliot M, Clish CB, Petasis NA, Van Dyke TE, Serhan CN. Lipoxin A4 analogues inhibit leukocyte recruitment to Porphyromonas gingivalis: A role for cyclooxygenase-2 and lipoxins in periodontal disease Biochemistry. 39: 4761-4768. PMID 10769133 DOI: 10.1021/Bi992551B  0.634
2000 Qiu FH, Wada K, Stahl GL, Serhan CN. IMP and AMP deaminase in reperfusion injury down-regulates neutrophil recruitment Proceedings of the National Academy of Sciences of the United States of America. 97: 4267-4272. PMID 10760293 DOI: 10.1073/Pnas.97.8.4267  0.397
2000 Chiang N, Fierro IM, Gronert K, Serhan CN. Activation of lipoxin A4 receptors by aspirin-triggered lipoxins and select peptides evokes ligand-specific responses in inflammation Journal of Experimental Medicine. 191: 1197-1207. PMID 10748237 DOI: 10.1084/Jem.191.7.1197  0.312
2000 Bandeira-Melo C, Bozza PT, Diaz BL, Cordeiro RS, Jose PJ, Martins MA, Serhan CN. Cutting edge: lipoxin (LX) A4 and aspirin-triggered 15-epi-LXA4 block allergen-induced eosinophil trafficking. Journal of Immunology (Baltimore, Md. : 1950). 164: 2267-71. PMID 10679058 DOI: 10.4049/Jimmunol.164.5.2267  0.385
2000 Serhan CN, Takano T, Chiang N, Gronert K, Clish CB. Formation of endogenous 'antiinflammatory' lipid mediators by transcellular biosynthesis: Lipoxins and aspirin-triggered lipoxins inhibit neutrophil recruitment and vascular permeability American Journal of Respiratory and Critical Care Medicine. 161. PMID 10673235 DOI: 10.1164/Ajrccm.161.Supplement_1.Ltta-19  0.421
2000 Serhan CN, Takano T, Clish CB, Gronert K, Petasis N. Aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogs inhibit neutrophil-mediated changes in vascular permeability Advances in Experimental Medicine and Biology. 469: 287-293. PMID 10667343 DOI: 10.1007/978-1-4615-4793-8_42  0.608
2000 Wright HM, Clish CB, Mikami T, Hauser S, Yanagi K, Hiramatsu R, Serhan CN, Spiegelman BM. A synthetic antagonist for the peroxisome proliferator-activated receptor gamma inhibits adipocyte differentiation. The Journal of Biological Chemistry. 275: 1873-7. PMID 10636887 DOI: 10.1074/Jbc.275.3.1873  0.313
2000 Bandeira-Melo C, Serra MF, Diaz BL, Cordeiro RS, Silva PM, Lenzi HL, Bakhle YS, Serhan CN, Martins MA. Cyclooxygenase-2-derived prostaglandin E2 and lipoxin A4 accelerate resolution of allergic edema in Angiostrongylus costaricensis-infected rats: relationship with concurrent eosinophilia. Journal of Immunology (Baltimore, Md. : 1950). 164: 1029-36. PMID 10623853 DOI: 10.4049/Jimmunol.164.2.1029  0.302
1999 Titos E, Chiang N, Serhan CN, Romano M, Gaya J, Pueyo G, Clària J. Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A. American Journal of Physiology. Cell Physiology. 277: C870-C877. PMID 29590867 DOI: 10.1152/Ajpcell.1999.277.5.C870  0.339
1999 Pouliot M, Serhan CN. Lipoxin A4 and aspirin-triggered 15-epi-LXA4 inhibit tumor necrosis factor-α-initiated neutrophil responses and trafficking: Novel regulators of a cytokine-chemokine axis relevant to periodontal diseases Journal of Periodontal Research. 34: 370-373. PMID 10685363 DOI: 10.1111/J.1600-0765.1999.Tb02268.X  0.364
1999 Filep JG, Zouki C, Petasis NA, Hachicha M, Serhan CN. Anti-inflammatory actions of lipoxin A4 stable analogs are demonstrable in human whole blood: Modulation of leukocyte adhesion molecules and inhibition of neutrophil-endothelial interactions Blood. 94: 4132-4142. PMID 10590058 DOI: 10.1182/Blood.V94.12.4132.424K25_4132_4142  0.582
1999 Chiang N, Gronert K, Clish CB, O'Brien JA, Freeman MW, Serhan CN. Leukotriene B4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion. The Journal of Clinical Investigation. 104: 309-16. PMID 10430612 DOI: 10.1172/Jci7016  0.349
1999 Clish CB, O'Brien JA, Gronert K, Stahl GL, Petasis NA, Serhan CN. Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo Proceedings of the National Academy of Sciences of the United States of America. 96: 8247-8252. PMID 10393980 DOI: 10.1073/Pnas.96.14.8247  0.599
1999 Hachicha M, Pouliot M, Petasis NA, Serhan CN. Lipoxin (LX)A4 and aspirin-triggered 15-epi-LXA4 inhibit tumor necrosis factor 1α-initiated neutrophil responses and trafficking: Regulators of a cytokine-chemokine axis Journal of Experimental Medicine. 189: 1923-1929. PMID 10377187 DOI: 10.1084/Jem.189.12.1923  0.584
1999 Serhan CN, Takano T, Gronert K, Chiang N, Clish CB. Lipoxin and aspirin-triggered 15-epi-lipoxin cellular interactions anti-inflammatory lipid mediators Clinical Chemistry and Laboratory Medicine. 37: 299-309. PMID 10353476 DOI: 10.1515/Cclm.1999.052  0.434
1999 Gronert K, Clish CB, Romano M, Serhan CN. Transcellular regulation of eicosanoid biosynthesis Methods in Molecular Biology (Clifton, N.J.). 120: 119-144. PMID 10343315 DOI: 10.1385/1-59259-263-5:119  0.319
1999 Levy BD, Fokin VV, Clark JM, Wakelam MJ, Petasis NA, Serhan CN. Polyisoprenyl phosphate (PIPP) signaling regulates phospholipase D activity: a 'stop' signaling switch for aspirin-triggered lipoxin A4. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 13: 903-11. PMID 10224233 DOI: 10.1096/Fasebj.13.8.903  0.601
1999 Gewirtz AT, Fokin VV, Petasis NA, Serhan CN, Madara JL. LXA4, aspirin-triggered 15-epi-LXA4, and their analogs selectively downregulate PMN azurophilic degranulation. The American Journal of Physiology. 276: C988-94. PMID 10199831 DOI: 10.1152/Ajpcell.1999.276.4.C988  0.656
1999 Serhan CN, Takano T, Maddox JF. Aspirin-triggered 15-epi-lipoxin A4 and stable analogs of lipoxin A4 are potent inhibitors of acute inflammation: Receptors and pathways Advances in Experimental Medicine and Biology. 447: 133-149. PMID 10086190 DOI: 10.1007/978-1-4615-4861-4_13  0.434
1999 Pouliot M, Hachicha M, Petasisz NA, Serhan CN. Lipoxin A4, and aspirin-triggered 15-epi-LXA4 inhibit TNFα-initiated neutropail responses and trafficking: Regulators of a cytokinechemokine axis Prostaglandins & Other Lipid Mediators. 59: 170. DOI: 10.1016/S0090-6980(99)90405-7  0.304
1999 Levy BD, Marshall CF, Serhan CN. Polyisoprenyl phosphate (PIPP) signaling regulates phospholipase D and superoxide anion generation in human neutrophils: Novel intracellular “stop” signals Prostaglandins & Other Lipid Mediators. 59: 128. DOI: 10.1016/S0090-6980(99)90363-5  0.32
1999 Chiang N, Gronert K, Clish CB, Freeman MW, Serhan CN. Lipoxin A4 and aspirin-triggered 15-epi-LXA are protective in acute inflammation and reperfusion injury in leukotriene B4 receptor transgenic mice Prostaglandins & Other Lipid Mediators. 59: 102. DOI: 10.1016/S0090-6980(99)90337-4  0.307
1999 Filep JG, Zouki C, Petasis NA, Hachicha M, Serhan CN. Anti-inflammatory actions of lipoxin-A4 stable analogs in human whole blood: Modulation of leukocyte adhesion molecule expression and inhibition of neutrophil-endothelial interactions Prostaglandins & Other Lipid Mediators. 59: 3. DOI: 10.1016/S0090-6980(99)90238-1  0.613
1998 Chiang N, Takano T, Clish CB, Petasis NA, Tai HH, Serhan CN. Aspirin-triggered 15-epi-lipoxin A4 (ATL) generation by human leukocytes and murine peritonitis exudates: development of a specific 15-epi-LXA4 ELISA. The Journal of Pharmacology and Experimental Therapeutics. 287: 779-90. PMID 9808710 DOI: 10.1016/S0090-6980(99)90421-5  0.614
1998 Gewirtz AT, McCormick B, Neish AS, Petasis NA, Gronert K, Serhan CN, Madara JL. Pathogen-induced chemokine secretion from model intestinal epithelium is inhibited by lipoxin A4 analogs. The Journal of Clinical Investigation. 101: 1860-9. PMID 9576749 DOI: 10.1172/Jci1339  0.62
1998 Gronert K, Gewirtz A, Madara JL, Serhan CN. Identification of a human enterocyte lipoxin A4 receptor that is regulated by interleukin (IL)-13 and interferon gamma and inhibits tumor necrosis factor alpha-induced IL-8 release. The Journal of Experimental Medicine. 187: 1285-94. PMID 9547339 DOI: 10.1084/Jem.187.8.1285  0.376
1998 Maddox JF, Colgan SP, Clish CB, Petasis NA, Fokin VV, Serhan CN. Lipoxin B4 regulates human monocyte/neutrophil adherence and motility: design of stable lipoxin B4 analogs with increased biologic activity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 12: 487-94. PMID 9535221 DOI: 10.1096/Fasebj.12.6.487  0.621
1998 Takano T, Clish CB, Gronert K, Petasis N, Serhan CN. Neutrophil-mediated changes in vascular permeability are inhibited by topical application of aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogues. The Journal of Clinical Investigation. 101: 819-26. PMID 9466977 DOI: 10.1172/Jci1578  0.62
1998 Gewirtz A, McCormick B, Neish A, Petasis N, Gronert K, Serhan C, Madara J. Release of pro-inflammatory chemokines from model intestinal epithelia is inhibited by lipoxin A4 analogs Gastroenterology. 114: A372. DOI: 10.1016/S0016-5085(98)81509-6  0.588
1997 Levy BD, Petasis NA, Serhan CN. Polyisoprenyl phosphates in intracellular signalling. Nature. 389: 985-90. PMID 9353124 DOI: 10.1038/40180  0.631
1997 Scalia R, Gefen J, Petasis NA, Serhan CN, Lefer AM. Lipoxin A4 stable analogs inhibit leukocyte rolling and adherence in the rat mesenteric microvasculature: role of P-selectin. Proceedings of the National Academy of Sciences of the United States of America. 94: 9967-72. PMID 9275235 DOI: 10.1073/Pnas.94.18.9967  0.561
1997 Takano T, Fiore S, Maddox JF, Brady HR, Petasis NA, Serhan CN. Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors. The Journal of Experimental Medicine. 185: 1693-704. PMID 9151906 DOI: 10.1084/Jem.185.9.1693  0.666
1997 Serhan CN. Lipoxins and novel aspirin-triggered 15-epi-lipoxins (ATL): A jungle of cell-cell interactions or a therapeutic opportunity? Prostaglandins. 53: 107-137. PMID 9112289 DOI: 10.1016/S0090-6980(97)00001-4  0.444
1997 Maddox JF, Hachicha M, Takano T, Petasis NA, Fokin VV, Serhan CN. Lipoxin A4 stable analogs are potent mimetics that stimulate human monocytes and THP-1 cells via a G-protein-linked lipoxin A4 receptor. The Journal of Biological Chemistry. 272: 6972-8. PMID 9054386 DOI: 10.1074/Jbc.272.11.6972  0.627
1996 Clària J, Lee MH, Serhan CN. Aspirin-triggered lipoxins (15-epi-LX) are generated by the human lung adenocarcinoma cell line (A549)-neutrophil interactions and are potent inhibitors of cell proliferation Molecular Medicine. 2: 583-596. PMID 8898374 DOI: 10.1007/Bf03401642  0.363
1996 Brady HR, Serhan CN. Lipoxins: Putative braking signals in host defense, inflammation and hypersensitivity Current Opinion in Nephrology and Hypertension. 5: 20-27. PMID 8834158 DOI: 10.1097/00041552-199601000-00006  0.418
1996 Serhan CN, Haeggström JZ, Leslie CC. Lipid mediator networks in cell signaling: Update and impact of cytokines Faseb Journal. 10: 1147-1158. PMID 8751717 DOI: 10.1096/Fasebj.10.10.8751717  0.389
1996 Maddox JF, Serhan CN. Lipoxin A4 and B4 are potent stimuli for human monocyte migration and adhesion: Selective inactivation by dehydrogenation and reduction Journal of Experimental Medicine. 183: 137-146. PMID 8551217 DOI: 10.1084/Jem.183.1.137  0.426
1995 Serhan CN, Romano M. Lipoxin biosynthesis and actions: role of the human platelet LX-synthase Journal of Lipid Mediators and Cell Signalling. 12: 293-306. PMID 8777573 DOI: 10.1016/0929-7855(95)00035-O  0.31
1995 Fiore S, Serhan CN. Lipoxin A4 receptor activation is distinct from that of the formyl peptide receptor in myeloid cells: Inhibition of CD11/18 expression by lipoxin A4-lipoxin A4 receptor interaction Biochemistry. 34: 16678-16686. PMID 8527441 DOI: 10.1021/Bi00051A016  0.328
1995 Serhan CN. Leukocyte transmigration, chemotaxis, and oxygenated derivatives of arachidonic acid: when is chirality important? American Journal of Respiratory Cell and Molecular Biology. 12: 251-253. PMID 7873189 DOI: 10.1165/Ajrcmb.12.3.7873189  0.432
1995 Datta YH, Romano M, Jacobson BC, Golan DE, Serhan CN, Ewenstein BM. Peptido-leukotrienes are potent agonists of von Willebrand factor secretion and P-selectin surface expression in human umbilical vein endothelial cells. Circulation. 92: 3304-11. PMID 7586318 DOI: 10.1161/01.Cir.92.11.3304  0.341
1995 Serhan CN, Maddox JF, Petasis NA, Akritopoulou-Zanze I, Papayianni A, Brady HR, Colgan SP, Madara JL. Design of lipoxin A4 stable analogs that block transmigration and adhesion of human neutrophils. Biochemistry. 34: 14609-15. PMID 7578068 DOI: 10.1021/Bi00044A041  0.613
1995 Clària J, Serhan CN. Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions Proceedings of the National Academy of Sciences of the United States of America. 92: 9475-9479. PMID 7568157 DOI: 10.1073/Pnas.92.21.9475  0.432
1995 Papayianni A, Serhan CN, Phillips ML, Rennke HG, Brady HR. Transcellular biosynthesis of lipoxin A4 during adhesion of platelets and neutrophils in experimental immune complex glomerulonephritis. Kidney International. 47: 1295-302. PMID 7543622 DOI: 10.1038/Ki.1995.184  0.396
1995 Brady HR, Papayianni A, Serhan CN. Potential vascular roles for lipoxins in the "stop programs" of host defense and inflammation Trends in Cardiovascular Medicine. 5: 186-192. DOI: 10.1016/1050-1738(95)00055-E  0.407
1994 Rowley AF, Lloyd-Evans P, Barrow SE, Serhan CN. Lipoxin biosynthesis by trout macrophages involves the formation of epoxide intermediates Biochemistry. 33: 856-863. PMID 8305432 DOI: 10.1021/Bi00170A002  0.394
1994 Serhan CN. Lipoxin biosynthesis and its impact in inflammatory and vascular events Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 1212: 1-25. PMID 8155718 DOI: 10.1016/0005-2760(94)90185-6  0.33
1994 Levy BD, Bertram S, Tai HH, Israel E, Fischer A, Drazen JM, Serhan CN. Agonist-induced lipoxin A4 generation: detection by a novel lipoxin A4-ELISA. Lipids. 28: 1047-53. PMID 8121246 DOI: 10.1007/Bf02537069  0.358
1994 Fiore S, Maddox JF, Perez HD, Serhan CN. Identification of a human cDNA encoding a functional high affinity lipoxin A4 receptor Journal of Experimental Medicine. 180: 253-260. PMID 8006586 DOI: 10.1084/Jem.180.1.253  0.324
1994 Takata S, Matsubara M, Allen PG, Janmey PA, Serhan CN, Brady HR. Remodeling of neutrophil phospholipids with 15(S)-hydroxyeicosatetraenoic acid inhibits leukotriene B4-induced neutrophil migration across endothelium Journal of Clinical Investigation. 93: 499-508. PMID 7906693 DOI: 10.1172/Jci116999  0.437
1994 Simchowitz L, Fiore S, Serhan CN. Carrier-mediated transport of lipoxin A4 in human neutrophils American Journal of Physiology - Cell Physiology. 267. PMID 7810593 DOI: 10.1152/Ajpcell.1994.267.6.C1525  0.391
1994 McManus M, Serhan C, Jackson P, Strange K. Ketoconazole blocks organic osmolyte efflux independently of its effect on arachidonic acid conversion American Journal of Physiology - Cell Physiology. 267. PMID 7519397 DOI: 10.1152/Ajpcell.1994.267.1.C266  0.365
1993 Serhan CN. Lipoxin A4 metabolism by differentiated HL-60 cells and human monocytes: Conversion to novel 15-oxo and dihydro products Biochemistry®. 32: 6313-6319. PMID 8518275 DOI: 10.1021/Bi00076A002  0.363
1993 Fiore S, Romano M, Reardon EM, Serhan CN. Induction of functional lipoxin A4 receptors in HL-60 cells Blood. 81: 3395-3403. PMID 8389617 DOI: 10.1182/Blood.V81.12.3395.3395  0.307
1993 Levy BO, Romano M, Chapman HA, Reilly JJ, Drazen J, Serhan CN. Human alveolar macrophages have 15-lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxins Journal of Clinical Investigation. 92: 1572-1579. PMID 8376607 DOI: 10.1172/Jci116738  0.395
1993 Colgan SP, Serhan CN, Parkos CA, Delp-Archer C, Madara JL. Lipoxin A4 modulates transmigration of human neutrophils across intestinal epithelial monolayers. The Journal of Clinical Investigation. 92: 75-82. PMID 8326019 DOI: 10.1172/Jci116601  0.379
1993 Romano M, Chen XS, Takahashi Y, Yamamoto S, Funk CD, Serhan CN. Lipoxin synthase activity of human platelet 12-lipoxygenase. The Biochemical Journal. 127-33. PMID 8250832 DOI: 10.1042/Bj2960127  0.333
1992 Roll FJ, Perez HD, Serhan CN. Characterization of a novel arachidonic acid-derived neutrophil chemoattractant Biochemical and Biophysical Research Communications. 186: 269-276. PMID 1632770 DOI: 10.1016/S0006-291X(05)80803-4  0.339
1992 Brady HR, Serhan CN. Adhesion promotes transcellular leukotriene biosynthesis during neutrophil-glomerular endothelial cell interactions: Inhibition by antibodies against CD18 and L-selectin Biochemical and Biophysical Research Communications. 186: 1307-1314. PMID 1380800 DOI: 10.1016/S0006-291X(05)81548-7  0.35
1992 Sheppard KA, Greenberg SM, Funk CD, Romano M, Serhan CN. Lipoxin generation by human megakaryocyte-induced 12-lipoxygenase. Biochimica Et Biophysica Acta. 1133: 223-34. PMID 1310055 DOI: 10.1016/0167-4889(92)90073-K  0.365
1992 Romano M, Serhan CN. Lipoxin generation by permeabilized human platelets Biochemistry. 31: 8269-8277. DOI: 10.1021/Bi00150A021  0.326
1991 Serhan CN. Lipoxins: Eicosanoids carrying intra-and intercellular messages Journal of Bioenergetics and Biomembranes. 23: 105-122. PMID 2010431 DOI: 10.1007/Bf00768841  0.395
1991 Brezinski DA, Serhan CN. Characterization of lipoxins by combined gas chromatography and electron-capture negative ion chemical ionization mass spectrometry: Formation of lipoxin A4 by stimulated human whole blood Biological Mass Spectrometry. 20: 45-52. PMID 1883860 DOI: 10.1002/Bms.1200200202  0.335
1991 Brady HR, Denton MD, Brenner BM, Serhan CN. Neutrophil adhesion to glomerular mesangial cells: Regulation by lipoxygenase-derived eicosanoids Advances in Experimental Medicine and Biology. 314: 347-359. PMID 1818493 DOI: 10.1007/978-1-4684-6024-7_24  0.339
1991 Fiore S, Brezinski ME, Sheppard KA, Serhan CN. The lipoxin biosynthetic circuit and their actions with human neutrophils. Advances in Experimental Medicine and Biology. 314: 109-32. PMID 1818482 DOI: 10.1007/978-1-4684-6024-7_7  0.439
1991 Nicolaou KC, Ramphal JY, Petasis NA, Serhan CN. Lipoxins and Related Eicosanoids: Biosynthesis, Biological Properties, and Chemical Synthesis Angewandte Chemie. 30: 1100-1116. DOI: 10.1002/Anie.199111001  0.608
1991 Nicolaou KC, Ramphal JY, Petasis NA, Serhan CN. Lipoxine und verwandte Eicosanoide: Biosynthese, biologische Eigenschaften und chemische Synthese Angewandte Chemie. 103: 1119-1136. DOI: 10.1002/Ange.19911030907  0.484
1991 Nicolaou KC, Ramphal JY, Petasis NA, Serhan CN. Lipoxins and related eicosanoids: Biosynthesis, biological properties, and chemical synthesis Angewandte Chemie (International Edition in English). 30: 1100-1116.  0.471
1990 Serhan CN. High-performance liquid chromatography separation and determination of lipoxins Methods in Enzymology. 187: 167-175. PMID 2233343 DOI: 10.1016/0076-6879(90)87022-U  0.33
1990 Brady HR, Persson U, Ballermann BJ, Brenner BM, Serhan CN. Leukotrienes stimulate neutrophil adhesion to mesangial cells: modulation with lipoxins. The American Journal of Physiology. 259: F809-15. PMID 2173421 DOI: 10.1152/Ajprenal.1990.259.5.F809  0.375
1990 Fiore S, Serhan CN. Formation of lipoxins and leukotrienes during receptor-mediated interactions of human platelets and recombinant human granulocyte/macrophage colony-stimulating factor-primed neutrophils Journal of Experimental Medicine. 172: 1451-1457. PMID 2172436 DOI: 10.1084/Jem.172.5.1451  0.365
1990 Nigam S, Fiore S, Luscinskas FW, Serhan CN. Lipoxin A4 and Li pox in B4 stimulate the release but not the oxygenation of arachidonic acid in human neutrophils: Dissociation between lipid remodeling and adhesion Journal of Cellular Physiology. 143: 512-523. PMID 2162850 DOI: 10.1002/Jcp.1041430316  0.4
1990 Lee TH, Crea AE, Gant V, Spur BW, Marron BE, Nicolaou KC, Reardon E, Brezinski M, Serhan CN. Identification of lipoxin A4 and its relationship to the sulfidopeptide leukotrienes C4, D4, and E4 in the bronchoalveolar lavage fluids obtained from patients with selected pulmonary diseases. The American Review of Respiratory Disease. 141: 1453-8. PMID 2161628 DOI: 10.1164/Ajrccm/141.6.1453  0.307
1990 Serhan CN, Sheppard KA. Lipoxin formation during human neutrophil-platelet interactions: Evidence for the transformation of leukotriene A4 by platelet 12-lipoxygenase in vitro Journal of Clinical Investigation. 85: 772-780. PMID 2155925 DOI: 10.1172/Jci114503  0.36
1990 Fiore S, Nicolaou KC, Caulfield T, Kataoka H, Serhan CN. Evaluation of synthetic sphingosine, lysosphingolipids and glycosphingolipids as inhibitors of functional responses of human neutrophils. The Biochemical Journal. 266: 25-31. PMID 2155608 DOI: 10.1042/Bj2660025  0.387
1990 Luscinskas FW, Nlcolaou KC, Webber SE, Veale CA, Gimbrone MA, Serhan CN. Ca2+ mobilization with leukotriene A4 and epoxytetraenes in human neutrophils Biochemical Pharmacology. 39: 355-365. PMID 2154229 DOI: 10.1016/0006-2952(90)90035-J  0.331
1990 Liu LX, Serhan CN, Weller PF. Intravascular filarial parasites elaborate cyclooxygenase-derived eicosanoids Journal of Experimental Medicine. 172: 993-996. PMID 2117642 DOI: 10.1084/Jem.172.3.993  0.332
1990 Brezinski ME, Serhan CN. Selective incorporation of (15S)-hydroxyeicosatetraenoic acid in phosphatidylinositol of human neutrophils: Agonist-induced deacylation and transformation of stored hydroxyeicosanoids Proceedings of the National Academy of Sciences of the United States of America. 87: 6248-6252. PMID 2117277 DOI: 10.1073/Pnas.87.16.6248  0.36
1989 Nicolaou KC, Marron BE, Veale CA, Webber SE, Dahlén SE, Samuelsson B, Serhan CN. Identification of a novel 7-cis-11-trans-lipoxin A4 generated by human neutrophils: total synthesis, spasmogenic activities and comparison with other geometric isomers of lipoxins A4 and B4. Biochimica Et Biophysica Acta. 1003: 44-53. PMID 2713393 DOI: 10.1016/0005-2760(89)90096-9  0.526
1989 Serhan CN. On the relationship between leukotriene and lipoxin production by human neutrophils: evidence for differential metabolism of 15-HETE and 5-HETE Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 1004: 158-168. PMID 2546590 DOI: 10.1016/0005-2760(89)90264-6  0.33
1989 Badr KF, DeBoer DK, Schwartzberg M, Serhan CN. Lipoxin A4 antagonizes cellular and in vivo actions of leukotriene D4 in rat glomerular mesangial cells: Evidence for competition at a common receptor Proceedings of the National Academy of Sciences of the United States of America. 86: 3438-3442. PMID 2541448 DOI: 10.1073/Pnas.86.9.3438  0.318
1989 Brezinski ME, Gimbrone MA, Nicolaou KC, Serhan CN. Lipoxins stimulate prostacyclin generation by human endothelial cells. Febs Letters. 245: 167-72. PMID 2494071 DOI: 10.1016/0014-5793(89)80214-5  0.343
1988 Brasseur R, Deleers M, Ruysschaert JM, Samuelsson B, Serhan CN. Conformational analysis of lipoxin A, lipoxin B and their trans-isomers. Biochimica Et Biophysica Acta. 960: 245-52. PMID 3365446 DOI: 10.1016/0005-2760(88)90070-7  0.521
1988 Serhan CN, Samuelsson B. Lipoxins: a new series of eicosanoids (biosynthesis, stereochemistry, and biological activities) Advances in Experimental Medicine and Biology. 229: 1-14. PMID 3048058 DOI: 10.1007/978-1-4757-0937-7_1  0.561
1987 Dahlén SE, Raud J, Serhan CN, Björk J, Samuelsson B. Biological activities of lipoxin A include lung strip contraction and dilation of arterioles in vivo. Acta Physiologica Scandinavica. 130: 643-7. PMID 3630737 DOI: 10.1111/J.1748-1716.1987.Tb08187.X  0.559
1987 Badr KF, Serhan CN, Nicolaou KC, Samuelsson B. The action of Lipoxin-A on glomerular microcirculatory dynamics in the rat Biochemical and Biophysical Research Communications. 145: 408-414. PMID 3593345 DOI: 10.1016/0006-291X(87)91337-4  0.444
1987 Palmblad J, Gyllenhammar H, Ringertz B, Serhan CN, Samuelsson B, Nicolaou KC. The effects of lipoxin A and lipoxin B on functional responses of human granulocytes. Biochemical and Biophysical Research Communications. 145: 168-75. PMID 3593338 DOI: 10.1016/0006-291X(87)91302-7  0.546
1987 Serhan CN, Hirsch U, Palmblad J, Samuelsson B. Formation of lipoxin A by granulocytes from eosinophilic donors Febs Letters. 217: 242-246. PMID 3109942 DOI: 10.1016/0014-5793(87)80671-3  0.549
1987 Lam BK, Serhan CN, Samuelsson B, Wong PYK. A phospholipase A2 isoenzyme provokes lipoxin B formation from endogenous sources of arachidonic acid in porcine leukocytes Biochemical and Biophysical Research Communications. 144: 123-131. PMID 3107549 DOI: 10.1016/S0006-291X(87)80484-9  0.55
1987 Serhan CN, Y.-K. Wong P, Samuelsson B. Nomenclature of lipoxins and related compounds derived from arachidonic acid and eicosapentaenoic acid Prostaglandins. 34: 201-204. PMID 2823318 DOI: 10.1016/0090-6980(87)90243-7  0.553
1987 Samuelsson B, Dahlén SE, Lindgren JA, Rouzer CA, Serhan CN. Leukotrienes and lipoxins: Structures, biosynthesis, and biological effects Science. 237: 1171-1176. PMID 2820055 DOI: 10.1126/Science.2820055  0.603
1986 Puustinen T, Webber SE, Nicolaou KC, Haeggström J, Serhan CN, Samuelsson B. Evidence for a 5(6)-epoxytetraene intermediate in the biosynthesis of lipoxins in human leukocytes. Conversion into lipoxin A by cytosolic epoxide hydrolase. Febs Letters. 207: 127-32. PMID 3770188 DOI: 10.1016/0014-5793(86)80025-4  0.563
1986 Serhan CN, Hamberg M, Samuelsson B, Morris J, Wishka DG. On the stereochemistry and biosynthesis of lipoxin B. Proceedings of the National Academy of Sciences of the United States of America. 83: 1983-7. PMID 3083410 DOI: 10.1073/Pnas.83.7.1983  0.534
1986 Hansson A, Serhan CN, Haeggström J, Ingelman-Sundberg M, Samuelsson B. Activation of protein kinase C by lipoxin A and other eicosanoids. Intracellular action of oxygenation products of arachidonic acid. Biochemical and Biophysical Research Communications. 134: 1215-22. PMID 2418836 DOI: 10.1016/0006-291X(86)90380-3  0.523
1985 Ramstedt U, Serhan CN, Lundberg U, Wigzell H, Samuelsson B. Inhibition of human natural killer cell activity by (14R,15S)-14,15-dihydroxy-5Z,8Z,10E,12E- icosatetraenoic acid. Proceedings of the National Academy of Sciences of the United States of America. 81: 6914-8. PMID 6095260 DOI: 10.1073/Pnas.81.22.6914  0.574
1985 Lundberg U, Serhan CN, Samuelsson B. Appearance of an arachidonic acid 15-lipoxygenase pathway upon differentiation of the human promyelocytic cell-line HL-60 Febs Letters. 185: 14-18. PMID 3922792 DOI: 10.1016/0014-5793(85)80731-6  0.543
1985 Aisen PS, Haines KA, Given W, Abramson SB, Pras M, Serhan C, Hamberg M, Samuelsson B, Weissmann G. Circulating hydroxy fatty acids in familial Mediterranean fever. Proceedings of the National Academy of Sciences of the United States of America. 82: 1232-6. PMID 3919389 DOI: 10.1073/Pnas.82.4.1232  0.568
1984 Serhan CN, Lundberg U, Lindgren JA, Weissmann G, Samuelsson B. Formation of leukotriene C4 by human leukocytes exposed to monosodium urate crystals Febs Letters. 167: 109-112. PMID 6698199 DOI: 10.1016/0014-5793(84)80842-X  0.523
1984 Serhan CN, Hamberg M, Samuelsson B. Trihydroxytetraenes: A novel series of compounds formed from arachidonic acid in human leukocytes Biochemical and Biophysical Research Communications. 118: 943-949. PMID 6422933 DOI: 10.1016/0006-291X(84)91486-4  0.54
1984 Weissmann G, Serhan C, Korchak HM, Smolen JE. Mechanisms of mediator release from neutrophils. Advances in Experimental Medicine and Biology. 172: 527-52. PMID 6328909 DOI: 10.1007/978-1-4615-9376-8_29  0.422
1984 Serhan CN, Lundberg U, Weissman G, Samuelsson B. Formation of leukotrienes and hydroxy acids by human neutrophils and platelets exposed to monosodium urate Prostaglandins. 27: 563-581. PMID 6328582 DOI: 10.1016/0090-6980(84)90092-3  0.579
1984 Serhan CN, Hamberg M, Samuelsson B. Lipoxins: Novel series of biologically active compounds formed from arachidonic acid in human leukocytes Proceedings of the National Academy of Sciences of the United States of America. 81: 5335-5339. PMID 6089195 DOI: 10.1073/Pnas.81.17.5335  0.563
1984 Marcus AJ, Safier LB, Broekman MJ, Ullman HL, Islam N, Sorrell TC, Serhan CN, Weissmann G, Oglesby TD, Gorman RR. Production of metabolic products of arachidonic acid during cell-cell interactions. The Journal of Allergy and Clinical Immunology. 74: 338-42. PMID 6088611 DOI: 10.1016/0091-6749(84)90126-X  0.371
1983 Serhan CN, Broekman MJ, Korchak HM, Smolen JE, Marcus AJ, Weissmann G. Changes in phosphatidylinositol and phosphatidic acid in stimulated human neutrophils. Relationship to calcium mobilization, aggregation and superoxide radical generation Bba - Molecular Cell Research. 762: 420-428. PMID 6303442 DOI: 10.1016/0167-4889(83)90007-1  0.344
1982 Serhan CN, Broekman MJ, Korchak HM, Marcus AJ, Weissman G. Endogenous phospholipid metabolism in stimulated neutrophils differential activation by FMLP and PMA Biochemical and Biophysical Research Communications. 107: 951-958. PMID 6814433 DOI: 10.1016/0006-291X(82)90615-5  0.311
1982 Weissmann G, Serhan C, Korchak HM, Smolen JE. Neutrophils: release of mediators of inflammation with special reference to rheumatoid arthritis. Annals of the New York Academy of Sciences. 389: 11-24. PMID 6807175 DOI: 10.1111/J.1749-6632.1982.Tb22122.X  0.416
1982 Marcus AJ, Broekman MJ, Safier LB, Ullman HL, Islam N, Serhan CN, Rutherford LE, Korchak HM, Weissmann G. Formation of leukotrienes and other hydroxy acids during platelet-neutrophil interactions in vitro Biochemical and Biophysical Research Communications. 109: 130-137. PMID 6297472 DOI: 10.1016/0006-291X(82)91575-3  0.352
1982 Serhan CN, Radin A, Smolen JE, Korchak H, Samuelsson B, Weissmann G. Leukotriene B4 is a complete secretagogue in human neutrophils: a kinetic analysis. Biochemical and Biophysical Research Communications. 107: 1006-12. PMID 6291511 DOI: 10.1016/0006-291X(82)90622-2  0.574
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