Gary E. Isom - Publications

Affiliations: 
Medicinal Chemistry and Molecular Pharmacology Purdue University, West Lafayette, IN, United States 
Area:
Toxicology
Website:
https://www.mcmp.purdue.edu/faculty/geisom

148 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Lee J, Kim JG, Mahon SB, Mukai D, Yoon D, Boss GR, Patterson SE, Rockwood G, Isom G, Brenner M. Noninvasive optical cytochrome c oxidase redox state measurements using diffuse optical spectroscopy. Journal of Biomedical Optics. 19: 055001. PMID 24788369 DOI: 10.1117/1.JBO.19.5.055001  1
2010 Leavesley HB, Li L, Mukhopadhyay S, Borowitz JL, Isom GE. Nitrite-mediated antagonism of cyanide inhibition of cytochrome c oxidase in dopamine neurons. Toxicological Sciences : An Official Journal of the Society of Toxicology. 115: 569-76. PMID 20335280 DOI: 10.1093/toxsci/kfq084  1
2010 Zhang L, Li L, Leavesley HW, Zhang X, Borowitz JL, Isom GE. Cyanide-induced apoptosis of dopaminergic cells is promoted by BNIP3 and Bax modulation of endoplasmic reticulum-mitochondrial Ca2+ levels. The Journal of Pharmacology and Experimental Therapeutics. 332: 97-105. PMID 19841471 DOI: 10.1124/jpet.109.159103  1
2009 Zhang L, Li L, Liu H, Borowitz JL, Isom GE. BNIP3 mediates cell death by different pathways following localization to endoplasmic reticulum and mitochondrion. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 3405-14. PMID 19535684 DOI: 10.1096/fj.08-124354  1
2009 Zhang X, Li L, Zhang L, Borowitz JL, Isom GE. Cyanide-induced death of dopaminergic cells is mediated by uncoupling protein-2 up-regulation and reduced Bcl-2 expression. Toxicology and Applied Pharmacology. 238: 11-9. PMID 19361538 DOI: 10.1016/j.taap.2009.03.020  1
2008 Borowitz JL, Isom GE. Nicotine and type 2 diabetes. Toxicological Sciences : An Official Journal of the Society of Toxicology. 103: 225-7. PMID 18353801 DOI: 10.1093/toxsci/kfn050  1
2008 Li L, Prabhakaran K, Zhang X, Zhang L, Liu H, Borowitz JL, Isom GE. 1Alpha,25-dihydroxyvitamin D3 attenuates cyanide-induced neurotoxicity by inhibiting uncoupling protein-2 up-regulation. Journal of Neuroscience Research. 86: 1397-408. PMID 18183618 DOI: 10.1002/jnr.21596  1
2008 Leavesley HB, Li L, Prabhakaran K, Borowitz JL, Isom GE. Interaction of cyanide and nitric oxide with cytochrome c oxidase: implications for acute cyanide toxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 101: 101-11. PMID 17906319 DOI: 10.1093/toxsci/kfm254  1
2007 Prabhakaran K, Li L, Zhang L, Borowitz JL, Isom GE. Upregulation of BNIP3 and translocation to mitochondria mediates cyanide-induced apoptosis in cortical cells Neuroscience. 150: 159-167. PMID 17980495 DOI: 10.1016/j.neuroscience.2007.07.033  1
2007 Zhang X, Li L, Prabhakaran K, Zhang L, Leavesley HB, Borowitz JL, Isom GE. Uncoupling protein-2 up-regulation and enhanced cyanide toxicity are mediated by PPARalpha activation and oxidative stress. Toxicology and Applied Pharmacology. 223: 10-9. PMID 17573087 DOI: 10.1016/j.taap.2007.05.002  1
2007 Zhang L, Li L, Liu H, Prabhakaran K, Zhang X, Borowitz JL, Isom GE. HIF-1alpha activation by a redox-sensitive pathway mediates cyanide-induced BNIP3 upregulation and mitochondrial-dependent cell death. Free Radical Biology & Medicine. 43: 117-27. PMID 17561100 DOI: 10.1016/j.freeradbiomed.2007.04.005  1
2006 Prabhakaran K, Li L, Borowitz JL, Isom GE. Inducible nitric oxide synthase up-regulation and mitochondrial glutathione depletion mediate cyanide-induced necrosis in mesencephalic cells Journal of Neuroscience Research. 84: 1003-1011. PMID 16933320 DOI: 10.1002/jnr.20998  1
2006 Zhang L, Li L, Prabhakaran K, Borowitz JL, Isom GE. Trimethyltin-induced apoptosis is associated with upregulation of inducible nitric oxide synthase and Bax in a hippocampal cell line Toxicology and Applied Pharmacology. 216: 34-43. PMID 16797631 DOI: 10.1016/j.taap.2006.05.004  1
2006 Li L, Prabhakaran K, Zhang X, Borowitz JL, Isom GE. PPARalpha-mediated upregulation of uncoupling protein-2 switches cyanide-induced apoptosis to necrosis in primary cortical cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 93: 136-45. PMID 16782780 DOI: 10.1093/toxsci/kfl039  1
2005 Prabhakaran K, Li L, Mills EM, Borowitz JL, Isom GE. Up-regulation of uncoupling protein 2 by cyanide is linked with cytotoxicity in mesencephalic cells. The Journal of Pharmacology and Experimental Therapeutics. 314: 1338-45. PMID 15937145 DOI: 10.1124/jpet.105.088625  1
2005 Li L, Prabhakaran K, Mills EM, Borowitz JL, Isom GE. Enhancement of cyanide-induced mitochondrial dysfunction and cortical cell cecrosis by uncoupling protein-2 Toxicological Sciences. 86: 116-124. PMID 15800031 DOI: 10.1093/toxsci/kfi164  1
2004 Gunasekar PG, Prabhakaran K, Li L, Zhang L, Isom GE, Borowitz JL. Receptor mechanisms mediating cyanide generation in PC12 cells and rat brain Neuroscience Research. 49: 13-18. PMID 15099699 DOI: 10.1016/j.neures.2004.01.006  1
2004 Prabhakaran K, Li L, Borowitz JL, Isom GE. Caspase inhibition switches the mode of cell death induced by cyanide by enhancing reactive oxygen species generation and PARP-1 activation. Toxicology and Applied Pharmacology. 195: 194-202. PMID 14998685 DOI: 10.1016/j.taap.2003.11.012  1
2004 Shou Y, Li L, Prabhakaran K, Borowitz JL, Isom GE. Calcineurin-mediated Bad translocation regulates cyanide-induced neuronal apoptosis. The Biochemical Journal. 379: 805-13. PMID 14741051 DOI: 10.1042/BJ20031107  1
2003 Shou Y, Li L, Prabhakaran K, Borowitz JL, Isom GE. p38 Mitogen-activated protein kinase regulates Bax translocation in cyanide-induced apoptosis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 75: 99-107. PMID 12805646 DOI: 10.1093/toxsci/kfg157  1
2003 Jones DC, Prabhakaran K, Li L, Gunasekar PG, Shou Y, Borowitz JL, Isom GE. Cyanide enhancement of dopamine-induced apoptosis in mesencephalic cells involves mitochondrial dysfunction and oxidative stress. Neurotoxicology. 24: 333-42. PMID 12782099 DOI: 10.1016/S0161-813X(03)00042-1  1
2002 Li L, Prabhakaran K, Shou Y, Borowitz JL, Isom GE. Oxidative stress and cyclooxygenase-2 induction mediate cyanide-induced apoptosis of cortical cells. Toxicology and Applied Pharmacology. 185: 55-63. PMID 12460737 DOI: 10.1006/taap.2002.9515  1
2002 Prabhakaran K, Li L, Borowitz JL, Isom GE. Cyanide induces different modes of death in cortical and mesencephalon cells Journal of Pharmacology and Experimental Therapeutics. 303: 510-519. PMID 12388630 DOI: 10.1124/jpet.102.039453  1
2002 Shou Y, Li N, Li L, Borowitz JL, Isom GE. NF-kappaB-mediated up-regulation of Bcl-X(S) and Bax contributes to cytochrome c release in cyanide-induced apoptosis. Journal of Neurochemistry. 81: 842-52. PMID 12065643 DOI: 10.1046/j.1471-4159.2002.00880.x  1
2001 Gunasekar PG, Mickova V, Kotyzova D, Li L, Borowitz JL, Eybl V, Isom GE. Role of astrocytes in trimethyltin neurotoxicity Journal of Biochemical and Molecular Toxicology. 15: 256-262. PMID 11835622 DOI: 10.1002/jbt.10004  1
2001 Li L, Shou Y, Borowitz JL, Isom GE. Reactive oxygen species mediate pyridostigmine-induced neuronal apoptosis: involvement of muscarinic and NMDA receptors. Toxicology and Applied Pharmacology. 177: 17-25. PMID 11708896 DOI: 10.1006/taap.2001.9283  1
2001 Gunasekar P, Li L, Prabhakaran K, Eybl V, Borowitz JL, Isom GE. Mechanisms of the apoptotic and necrotic actions of trimethyltin in cerebellar granule cells Toxicological Sciences. 64: 83-89. PMID 11606804  1
2000 Li L, Gunasekar PG, Borowitz JL, Isom GE. Muscarinic receptor-mediated pyridostigmine-induced neuronal apoptosis Neurotoxicology. 21: 541-552. PMID 11022862  1
2000 Gunasekar PG, Borowitz JL, Turek JJ, Van Horn DA, Isom GE. Endogenous generation of cyanide in neuronal tissue: involvement of a peroxidase system. Journal of Neuroscience Research. 61: 570-5. PMID 10956427 DOI: 10.1002/1097-4547(20000901)61:5<570::AID-JNR12>3.0.CO;2-V  1
2000 Jones DC, Gunasekar PG, Borowitz JL, Isom GE. Dopamine-induced apoptosis is mediated by oxidative stress and is enhanced by cyanide in differentiated PC12 cells Journal of Neurochemistry. 74: 2296-2304. PMID 10820189 DOI: 10.1046/j.1471-4159.2000.0742296.x  1
2000 Shou Y, Gunasekar PG, Borowitz JL, Isom GE. Cyanide-induced apoptosis involves oxidative-stress-activated NF-kappaB in cortical neurons. Toxicology and Applied Pharmacology. 164: 196-205. PMID 10764633 DOI: 10.1006/taap.2000.8900  1
2000 Eybl V, Kotyzová D, Míčková V, Koutenský J, Borowitz JL, Isom GE. Changes in organ distribution of cadmium, lead and manganese caused by cyanide in mice Biologia - Section Cellular and Molecular Biology. 55: 33-38.  0.64
1999 Sun P, Rane SG, Gunasekar PG, Borowitz JL, Isom GE. Cyanide interaction with redox modulatory sites enhances NMDA receptor responses Journal of Biochemical and Molecular Toxicology. 13: 253-259. PMID 10402559  1
1999 Mills EM, Gunasekar PG, Li L, Borowitz JL, Isom GE. Differential susceptibility of brain areas cyanide involves different modes of cell death Toxicology and Applied Pharmacology. 156: 6-16. PMID 10101094 DOI: 10.1006/taap.1999.8630  1
1998 Kane MD, Vanden Heuvel JP, Isom GE, Schwarz RD. Differential expression of group I metabotropic glutamate receptors (mGluRs) in the rat pheochromocytoma cell line PC12: Role of nerve growth factor and ras Neuroscience Letters. 252: 1-4. PMID 9756344 DOI: 10.1016/S0304-3940(98)00484-4  1
1998 Gunasekar PG, Borowitz JL, Isom GE. Cyanide-induced generation of oxidative species: Involvement of nitric oxide synthase and cyclooxygenase-2 Journal of Pharmacology and Experimental Therapeutics. 285: 236-241. PMID 9536016  1
1998 Kane MD, Yang CW, Gunasekar PG, Isom GE. Trimethyltin stimulates protein kinase C translocation through receptor- mediated phospholipase C activation in PC12 cells Journal of Neurochemistry. 70: 509-514. PMID 9453544  1
1997 Kanthasamy AG, Ardelt B, Malave A, Mills EM, Powley TL, Borowitz JL, Isom GE. Reactive oxygen species generated by cyanide mediate toxicity in rat pheochromocytoma cells. Toxicology Letters. 93: 47-54. PMID 9381482 DOI: 10.1016/S0378-4274(97)00068-4  1
1997 Borowitz JL, Gunasekar PG, Isom GE. Hydrogen cyanide generation by μ-opiate receptor activation: Possible neuromodulatory role of endogenous cyanide Brain Research. 768: 294-300. PMID 9369328 DOI: 10.1016/S0006-8993(97)00659-8  1
1997 Bitner RS, Yim GKW, Isom GE. 2-Iminothiazolidine-4-carboxylic acid produces hippocampal CA1 lesions independent of seizure excitation and glutamate receptor activation Neurotoxicology. 18: 191-200. PMID 9216001  1
1997 Sun P, Rane SG, Gunasekar PG, Borowitz JL, Isom GE. Modulation of the NMDA receptor by cyanide: Enhancement of receptor- mediated responses Journal of Pharmacology and Experimental Therapeutics. 280: 1341-1348. PMID 9067322  1
1996 Yang CW, Borowitz JL, Gunasekar PG, Isom GE. Cyanide-stimulated inositol 1,4,5-trisphosphate formation: An intracellular neurotoxic signaling cascade Journal of Biochemical Toxicology. 11: 251-256. PMID 9110247  1
1996 Mills EM, Gunasekar PG, Pavlakovic G, Isom GE. Cyanide-induced apoptosis and oxidative stress in differentiated PC12 cells Journal of Neurochemistry. 67: 1039-1046. PMID 8752110  1
1996 Gunasekar PG, Sun PW, Kanthasamy AG, Borowitz JL, Isom GE. Cyanide-induced neurotoxicity involves nitric oxide and reactive oxygen species generation after N-methyl-D-aspartate receptor activation. The Journal of Pharmacology and Experimental Therapeutics. 277: 150-5. PMID 8613912  1
1995 Gunasekar PG, Kanthasamy AG, Borowitz JL, Isom GE. Monitoring intracellular nitric oxide formation by dichlorofluorescin in neuronal cells Journal of Neuroscience Methods. 61: 15-21. PMID 8618413 DOI: 10.1016/0165-0270(95)00018-P  1
1995 Isom GE, Borowitz JL. Modification of cyanide toxicodynamics: mechanistic based antidote development Toxicology Letters. 82: 795-799. PMID 8597144 DOI: 10.1016/0378-4274(95)03521-4  1
1995 Sun P, Borowitz JL, Kanthasamy AG, Kane MD, Gunasekar PG, Isom GE. Antagonism of cyanide toxicity by isosorbide dinitrate: possible role of nitric oxide. Toxicology. 104: 105-11. PMID 8560488 DOI: 10.1016/0300-483X(95)03152-6  1
1995 Kanthasamy AG, Isom GE, Borowitz JL. Role of intracellular Cd2+ in catecholamine release and lethality in PC12 cells. Toxicology Letters. 81: 151-7. PMID 8553369 DOI: 10.1016/0378-4274(95)03425-0  1
1995 Pavlaković G, Eyer CL, Isom GE. Neuroprotective effects of PKC inhibition against chemical hypoxia Brain Research. 676: 205-211. PMID 7796171 DOI: 10.1016/0006-8993(95)00094-7  1
1995 Dawson R, Beal MF, Bondy SC, Dimonte DA, Isom GE. Excitotoxins, Aging, and Environmental Neurotoxins: Implications for Understanding Human Neurodegenerative Diseases Toxicology and Applied Pharmacology. 134: 1-17. PMID 7676443 DOI: 10.1006/taap.1995.1163  1
1995 Bitner RS, Kanthasamy A, Isom GE, Yim GKW. Seizures and selective CA-1 hippocampal lesions induced by an excitotoxic cyanide metabolite, 2-iminothiazolidine-4-carboxylic acid Neurotoxicology. 16: 115-122. PMID 7603631  1
1995 Pavlaković G, Kane MD, Eyer CL, Kanthasamy A, Isom GE. Activation of protein kinase C by trimethyltin: relevance to neurotoxicity. Journal of Neurochemistry. 65: 2338-43. PMID 7595523  1
1995 Gunasekar PG, Kanthasamy AG, Borowitz JL, Isom GE. NMDA receptor activation produces concurrent generation of nitric oxide and reactive oxygen species: Implication for cell death Journal of Neurochemistry. 65: 2016-2021. PMID 7595485  1
1995 Sun P, Kanthasamy A, Yim GK, Isom GE. Inhibition of potassium-stimulated dopamine release by the nitric oxide generator isosorbide dinitrate. Neuropharmacology. 34: 205-10. PMID 7542370 DOI: 10.1016/0028-3908(94)00151-H  1
1994 Ardelt BK, Borowitz JL, Maduh EU, Swain SL, Isom GE. Cyanide-induced lipid peroxidation in different organs: subcellular distribution and hydroperoxide generation in neuronal cells Toxicology. 89: 127-137. PMID 8197590 DOI: 10.1016/0300-483X(94)90221-6  1
1994 Yang CW, Rathinavelu A, Borowitz JL, Isom GE. Activation of a calcium- and pH-dependent phospholipase A2 by cyanide in PC12 cells Toxicology and Applied Pharmacology. 124: 262-267. PMID 8122272 DOI: 10.1006/taap.1994.1031  1
1994 Latha MV, Borowitz JL, Yim GKW, Kanthasamy A, Isom GE. Plasma membrane hyperpolarization by cyanide in chromaffin cells: role of potassium channels Archives of Toxicology. 68: 370-374. PMID 8092929 DOI: 10.1007/s002040050084  1
1994 Borowitz JL, Rathinavelu A, Kanthasamy A, Wilsbacher J, Isom GE. Accumulation of Labeled Cyanide in Neuronal Tissue Toxicology and Applied Pharmacology. 129: 80-85. PMID 7974498 DOI: 10.1006/taap.1994.1230  1
1994 Kanthasamy AG, Borowitz JL, Pavlakovic G, Isom GE. Dopaminergic neurotoxicity of cyanide: Neurochemical, histological, and behavioral characterization Toxicology and Applied Pharmacology. 126: 156-163. PMID 7910421 DOI: 10.1006/taap.1994.1102  1
1994 Pavlaković G, Rathinavelu A, Isom GE. MK-801 prevents cyanide-induced changes of fos levels in rat brain Neurochemical Research. 19: 1289-1294. PMID 7891846 DOI: 10.1007/BF01006820  1
1994 Rathinavelu A, Sun P, Pavlakovic G, Borowitz JL, Isom GE. Cyanide induces protein kinase C translocation: Blockade by NMDA antagonists J.Biochem.Toxicol.. 9: 235-240. PMID 7853358  1
1994 Kanthasamy AG, Rathinavelu A, Borowitz JL, Isom GE. Interaction of cyanide with a dopamine metabolite: Formation of a cyanohydrin adduct and its implications for cyanide-induced neurotoxicity Neurotoxicology. 15: 887-896. PMID 7715859  1
1994 Patel MN, Peoples RW, Yim GKW, Isom GE. Enhancement of NMDA-mediated responses by cyanide Neurochemical Research. 19: 1319-1323. PMID 7534385 DOI: 10.1007/BF01006824  1
1993 Rathunavelu A, Isom GE. Lysosomal delivery of ANP receptors following internalization in PC12 cell Life Sciences. 53: 1007-1014. PMID 8361324 DOI: 10.1016/0024-3205(93)90123-K  1
1993 Patel MN, Yim GKW, Isom GE. N-methyl-D-aspartate receptors mediate cyanide-induced cytotoxicity in hippocampal cultures Neurotoxicology. 14: 35-40. PMID 8103209  1
1993 Borowitz JL, Kanthasamy AG, Mitchell PJ, Isom GE. Use of PC12 cells as a neurotoxicological screen: Characterization of anticyanide compounds Toxicological Sciences. 20: 133-140. DOI: 10.1093/toxsci/20.2.133  1
1992 Giridhar J, Rathinavelu A, Isom GE. Interaction of cadmium with atrial natriuretic peptide receptors: Implications for toxicity Toxicology. 75: 133-143. PMID 1462351 DOI: 10.1016/0300-483X(92)90152-5  1
1992 Patel MN, Yim GKW, Isom GE. Potentiation of cyanide neurotoxicity by blockade of ATP-sensitive potassium channels Brain Research. 593: 114-116. PMID 1458312 DOI: 10.1016/0006-8993(92)91271-F  1
1992 Giridhar J, Peoples RW, Isom GE. Modulation of hypothalamic norepinephrine release by atrial natriuretic peptide: involvement of cyclic GMP. European Journal of Pharmacology. 213: 317-21. PMID 1377629 DOI: 10.1016/0014-2999(92)90619-F  1
1992 Patel MN, Yim GKW, Isom GE. Blockade of N-methyl-d-aspartate receptors prevents cyanide-induced neuronal injury in primary hippocampal cultures Toxicology and Applied Pharmacology. 115: 124-129. PMID 1352919 DOI: 10.1016/0041-008X(92)90375-3  1
1991 Maduh EU, Borowitz JL, Isom GE. Cyanide-induced alteration of the adenylate energy pool in a rat neurosecretory cell line Journal of Applied Toxicology. 11: 97-101. PMID 2061557  1
1991 Peoples RW, Giridhar J, Isom GE. γ-aminobutyric acid enhancement of potassium-stimulated release of [3H]norepinephrine by multiple mechanisms in rat cortical slices Biochemical Pharmacology. 41: 119-123. PMID 1986736 DOI: 10.1016/0006-2952(91)90019-2  1
1991 Kanthasamy AG, Maduh EU, Peoples RW, Borowitz JL, Isom GE. Calcium mediation of cyanide-induced catecholamine release: Implications for neurotoxicity Toxicology and Applied Pharmacology. 110: 275-282. PMID 1909818 DOI: 10.1016/S0041-008X(05)80010-9  1
1991 Rathinavelu A, Isom GE. Regulation of ANF receptor internalization: Involvement of extracellular calcium Biochemical and Biophysical Research Communications. 175: 1017-1022. PMID 1850991 DOI: 10.1016/0006-291X(91)91666-Z  1
1991 Giridhar J, Isom GE. Alteration of atrial natriuretic peptide levels by short term cadmium treatment Toxicology. 70: 185-194. PMID 1837192 DOI: 10.1016/0300-483X(91)90045-3  1
1991 Kanthasamy AG, Borowitz JL, Isom GE. Cyanide-induced increases in plasma catecholamines: Relationship to acute toxicity Neurotoxicology. 12: 777-784. PMID 1795901  1
1991 Peoples RW, Giridhar J, Isom GE. γ-aminobutyric acidA (GABAA) receptor modulation of morphine inhibition of norepinephrine release Biochemical Pharmacology. 42. PMID 1662949 DOI: 10.1016/0006-2952(91)90401-P  1
1991 Rathinavelu A, Isom GE. Differential internalization and processing of atrial-natriuretic-factor B and C receptors in PC12 cells Biochemical Journal. 276: 493-497. PMID 1646602  1
1991 Patel MN, Ardelt BK, Yim GKW, Isom GE. Cyanide induces Ca2+-dependent and -independent release of glutamate from mouse brain slices Neuroscience Letters. 131: 42-44. DOI: 10.1016/0304-3940(91)90332-N  1
1990 Maduh EU, Turek JJ, Borowitz JL, Rebar A, Isom GE. Cyanide-induced neurotoxicity: calcium mediation of morphological changes in neuronal cells. Toxicology and Applied Pharmacology. 103: 214-21. PMID 2330585 DOI: 10.1016/0041-008X(90)90224-I  1
1990 Maduh EU, Borowitz JL, Isom GE. Cyanide-induced alteration of cytosolic pH: Involvement of cellular hydrogen ion handling processes Toxicology and Applied Pharmacology. 106: 201-208. PMID 2256111 DOI: 10.1016/0041-008X(90)90240-U  1
1990 Giridhar J, Isom GE. Interaction of lead acetate with atrial natriuretic factor in rats Life Sciences. 46: 569-576. PMID 2137898 DOI: 10.1016/0024-3205(90)90124-A  1
1990 Patel M, Ardelt BK, Yim GKW, Isom GE. Interaction of trimethyltin with hippocampal glutamate Neurotoxicology. 11: 601-608. PMID 2128396  1
1989 Ardelt BK, Borowitz JL, Isom GE. Brain lipid peroxidation and antioxidant protectant mechanisms following acute cyanide intoxication Toxicology. 56: 147-154. PMID 2734799 DOI: 10.1016/0300-483X(89)90129-7  1
1989 Conroy WG, Peoples RW, Isom GE. Identification of functional beta-adrenergic receptors on AC glioma cells Biochemical Pharmacology. 38: 3175-3178. PMID 2554917 DOI: 10.1016/0006-2952(89)90610-2  1
1989 Rathinavelu A, Isom GE. Production of a monoclonal antibody against C terminus of atrial natriuretic factor by in vitro immunization Biochemical and Biophysical Research Communications. 162: 634-638. PMID 2527033 DOI: 10.1016/0006-291X(89)92357-7  1
1989 Howell SR, Christian JE, Isom GE. Alteration of hepatic lipid metabolism by combined toluene-ethanol exposure Research Communications in Substances of Abuse. 10: 81-94.  1
1988 Borowitz JL, Born GS, Isom GE. Potentiation of evoked adrenal catecholamine release by cyanide: Possible role of calcium Toxicology. 50: 37-45. PMID 3388429 DOI: 10.1016/0300-483X(88)90119-9  1
1988 Golub ES, Diaz De' Pagan T, Sun I, Hall AK, Crane FL, Isom G. Can opioids regulate hemopoietic differentiation? Annals of the New York Academy of Sciences. 521: 123-8. PMID 3288038 DOI: 10.1111/j.1749-6632.1988.tb35270.x  1
1988 Maduh EU, Johnson JD, Ardelt BK, Borowitz JL, Isom GE. Cyanide-induced neurotoxicity: Mechanisms of attenuation by chlorpromazine Toxicology and Applied Pharmacology. 96: 60-67. PMID 3188027 DOI: 10.1016/0041-008X(88)90247-5  1
1988 Rathinavelu A, Isom GE. High affinity receptors for atrial natriuretic factor in PC12 cells Biochemical and Biophysical Research Communications. 156: 78-85. PMID 2845987 DOI: 10.1016/S0006-291X(88)80807-6  1
1987 Johnson JD, Conroy WG, Burris KD, Isom GE. Peroxidation of brain lipids following cyanide intoxication in mice Toxicology. 46: 21-28. PMID 3660418 DOI: 10.1016/0300-483X(87)90134-X  1
1987 Johnson JD, Conroy WG, Isom GE. Effect of pentobarbital on cyanide-induced tremors in mice and calcium accumulation in PC12 cells Biochemical Pharmacology. 36: 1747-1749. PMID 3593396 DOI: 10.1016/0006-2952(87)90064-5  1
1987 Johnson JD, Conroy WG, Isom GE. Alteration of cytosolic calcium levels in PC12 cells by potassium cyanide. Toxicology and Applied Pharmacology. 88: 217-24. PMID 3564040 DOI: 10.1016/0041-008X(87)90007-X  1
1987 Borowitz JL, Stebbins G, Isom GE, Johnson JD. Studies of the hypotensive effect of calcium injected into lateral brain ventricles Research Communications in Chemical Pathology and Pharmacology. 55: 67-74. PMID 3563107  1
1987 Conroy WG, Isom GE. Affinity chromatography of the opiate receptor from toad brain utilizing a 3-O-carboxymethylmorphine-Sepharose matrix Biochemical Archives. 3: 53-59.  1
1987 Howell SR, Christian JE, Isom GE. Interaction of acute ethanol and toluene effects of hepatic lipid metabolism and ethanol disposition Research Communications in Substances of Abuse. 8: 17-27.  1
1986 Johnson JD, Meisenheimer TL, Isom GE. A new method for quantification of tremors in mice Journal of Pharmacological Methods. 16: 329-337. PMID 3784575 DOI: 10.1016/0160-5402(86)90035-5  1
1986 Howell SR, Christian JE, Isom GE. The hepatotoxic potential of combined toluene-chronic ethanol exposure Archives of Toxicology. 59: 45-50. PMID 3741143 DOI: 10.1007/BF00263957  1
1986 Johnson JD, Meisenheimer TL, Isom GE. Cyanide-induced neurotoxicity: Role of neuronal calcium Toxicology and Applied Pharmacology. 84: 464-469. PMID 3726869 DOI: 10.1016/0041-008X(86)90251-6  1
1985 Johnson JD, Isom GE. The oxidative disposition of potassium cyanide in mice Toxicology. 37: 215-224. PMID 3000027 DOI: 10.1016/0300-483X(85)90084-8  1
1985 Ng DSS, Isom GE. Anti-morphine anti-idiotypic antibodies. Opiate receptor binding and isolated tissue responses Biochemical Pharmacology. 34: 2853-2858. PMID 2992520 DOI: 10.1016/0006-2952(85)90006-1  1
1985 Johnson JD, Isom GE. Quantification of expired metabolites following potassium cyanide administration: A new method Journal of Analytical Toxicology. 9: 112-115. PMID 2989616 DOI: 10.1093/jat/9.3.112  1
1985 Bryant HU, Conroy WG, Isom GE, Malven PV, Yim GKW. Presence of dynorphin-like immunoreactivity but not opiate binding in Walker-256 tumors Life Sciences. 37: 155-160. PMID 2861551 DOI: 10.1016/0024-3205(85)90418-7  1
1985 Johnson JD, Mayer PR, Isom GE. Pharmacokinetic analysis of potassium cyanate in mice using whole blood and expired air Drug Metabolism and Disposition. 13: 260-262. PMID 2859178  1
1985 Johnson JD, Conroy WG, Isom GE. Cyanide induced intracellular calcium accumulation in mouse brain Federation Proceedings. 44.  1
1985 Conroy WG, Johnson JD, Isom GE. Affinity chromatography of opioid receptors utilizing a naloxone-sepharose matrix Federation Proceedings. 44.  1
1984 Isom GE, Way JL. Effects of oxygen on the antagonism of cyanide intoxication: Cytochrome oxidase, in vitro Toxicology and Applied Pharmacology. 74: 57-62. PMID 6328698 DOI: 10.1016/0041-008X(84)90269-2  1
1984 Way JL, Sylvester D, Morgan RL, Isom GE, Burrows GE, Tamulinas CB, Way JL. Recent perspectives on the toxicodynamic basis of cyanide antagonism. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 4: S231-9. PMID 6327443  1
1984 Ng DS, Isom GE. Binding of antimorphine anti-idiotypic antibodies to opiate receptors European Journal of Pharmacology. 102: 187-190. PMID 6090156 DOI: 10.1016/0014-2999(84)90357-1  1
1984 Way JL, Sylvester D, Morgan RL, Isom GE, Burrows GE, Tamulinas CB. Recent perspectives on the toxicodynamic basis of cyanide antagonism Toxicological Sciences. 4: 231-239. DOI: 10.1016/0272-0590(84)90157-X  1
1984 Johnson JD, Isom GE. The effect of the superoxide dismutase system on the oxidative metabolism of cyanide Federation Proceedings. 43.  1
1984 Isom GE, Ng DS, Abdul-Wahid F. Attenuation of opiate responses by antimorphine anti-idiotypic antibodies Federation Proceedings. 43.  1
1983 Khairy L, Isom GE, Kildsig DO. Reversal of acetaminophen intoxication with an N-acetylcysteine-liposome preparation Research Communications in Chemical Pathology and Pharmacology. 42: 153-156. PMID 6648037  1
1983 Kong A, Shen A, Burrows G, Sylvester D, Isom GE, Way JL. Effect of chlorpromazine on cyanide intoxication Toxicology and Applied Pharmacology. 71: 407-413. PMID 6318390 DOI: 10.1016/0041-008X(83)90028-5  1
1983 Johnson JD, White HS, Isom GE. Local application of cyclic AMP in the rat brain: characterization of the cardiovascular response. European Journal of Pharmacology. 91: 343-51. PMID 6311585 DOI: 10.1016/0014-2999(83)90157-7  1
1982 Burrows GE, Liu DHW, Isom GE, Way JL. Effect of antagonists on the physiologic disposition of sodium cyanide Journal of Toxicology and Environmental Health. 10: 181-189. PMID 7143474 DOI: 10.1080/15287398209530242  1
1982 Isom GE, Elshowihy RM. Interaction of acute and chronic stress with respiration: Modification by naloxone Pharmacology, Biochemistry and Behavior. 16: 599-603. PMID 6803252 DOI: 10.1016/0091-3057(82)90422-1  1
1982 Isom GE, Burrows GE, Way JL. Effect of oxygen on the antagonism of cyanide intoxication-cytochrome oxidase, in vivo Toxicology and Applied Pharmacology. 65: 250-256. PMID 6294919 DOI: 10.1016/0041-008X(82)90007-2  1
1982 Isom GE, Elshowihy RM. Naloxone-induced enhancement of carbon dioxide stimulated respiration Life Sciences. 31: 113-118. PMID 6289028 DOI: 10.1016/0024-3205(82)90422-2  1
1981 Zobrist RH, Allerton HW, Isom GE. Characterization of the respiratory activity of (D-Ala2)methionine-enkephalinamide European Journal of Pharmacology. 70: 121-128. PMID 6790294 DOI: 10.1016/0014-2999(81)90206-5  1
1981 Meldrum MJ, Isom GE. Role of monoaminergic systems in morphine-induced respiratory depression Neuropharmacology. 20: 169-175. PMID 6163106 DOI: 10.1016/0028-3908(81)90200-8  1
1981 Isom GE, Elshowihy R. Stimulation of respiration by naloxone in normal and stressed rats Federation Proceedings. 40: 271.  1
1981 Si CC, Abdul-Wahid F, Isom GE. Characterization of antiopioid receptor antibodies Federation Proceedings. 40: 160.  1
1980 Ganjeloo A, Isom GE, Morgan RL, Way JL. Fluorometric determination of cyanide in biological fluids with p-benzoquinone Toxicology and Applied Pharmacology. 55: 103-107. PMID 7423496  1
1980 Isom GE, Meldrum MJ. Morphine induced respiratory depression: involvement of norepinephrine and serotonin Proceedings of the Western Pharmacology Society. 89-91. PMID 7403171  1
1980 White HS, Isom GE. Localization of the central cardiovascular action of dibutyryl cyclic AMP. Proceedings of the Western Pharmacology Society. 23: 33-5. PMID 6250153  1
1980 Wahid FA, Isom GE. Affinity chromatography of antimorphine antibodies Research Communications in Substances of Abuse. 1: 451-458.  1
1979 Wahid FA, Meisheri KD, Isom GE. Suppression of morphine physical dependence and tolerance by immune activation Proceedings of the Western Pharmacology Society. 483-488. PMID 574647  1
1979 Zobrist RH, Allerton HW, Isom GE. Effect of d-ala2-methionine-enkephalinamide on respiration Proceedings of the Western Pharmacology Society. 475-477. PMID 515092  1
1979 Addo MF, Isom GE. Chronic intracerebroventricular infusion of angiotensin II Proceedings of the Western Pharmacology Society. 247-249. PMID 515059  1
1979 White HS, Driver PS, Isom GE. Studies on the central pressor activity of dibutyryl cyclic AMP. European Journal of Pharmacology. 57: 107-13. PMID 226371 DOI: 10.1016/0014-2999(79)90356-X  1
1979 Morgan RL, Isom GE, Way JL. Resolution of thiosulfate interference in cyanide determination Toxicology and Applied Pharmacology. 50: 323-328. PMID 41341 DOI: 10.1016/0041-008X(79)90158-3  1
1978 Mann PA, Isom GE. A model for the rapid induction of barbiturate tolerance Proceedings of the Western Pharmacology Society. 387-390. PMID 693521  1
1978 Meisheri KD, Isom GE. Influence of immune stimulation and suppression on morphine physical dependence and tolerance Research Communications in Chemical Pathology and Pharmacology. 19: 85-99. PMID 564538  1
1978 White HS, Isom GE. Central effects of N6, O2'-dibutyryl adenosine 3',5'-cyclic monophosphate on blood pressure. Proceedings of the Western Pharmacology Society. 21: 253-6. PMID 211527  1
1978 Isom GE, McCarthy TA, Eells JT, Wimer ER. Influence of intracerebroventricular injections of N6, O2'-dibutyryl adenosine 3':5'-cyclic monophosphate on sodium pentobarbital-induced narcosis in rats Neuropharmacology. 17: 53-58. PMID 206854 DOI: 10.1016/0028-3908(78)90173-9  1
1978 Isom GE, Meisheri KD, Meldrum MJ. A long-acting silicone delivery system for morphine and naloxone administration Journal of Pharmacological Methods. 1: 121-129. DOI: 10.1016/0160-5402(78)90017-7  1
1976 Morgan R, Isom GE, Way JL. A fluorometric method for determination of cyanide in biological fluids Proceedings of the Western Pharmacology Society. 392-396. PMID 996012  1
1976 Isom GE, Eells JT, Wimer ER. Effects of N6,O2' dibutyryl adenosine 3':5' cyclic monophosphate on the actions of pentobarbital Proceedings of the Western Pharmacology Society. 445-447. PMID 186811  1
1976 Isom GE, Way JL. Lethality of cyanide in the absence of inhibition of liver cytochrome oxidase Biochemical Pharmacology. 25: 605-608. PMID 182178 DOI: 10.1016/0006-2952(76)90397-X  1
1975 Dodson RA, Burrows GE, Isom GE, Way JL. Mechanism of chlorpromazine antagonism of cyanide intoxication. Proceedings of the Western Pharmacology Society. 18: 348-50. PMID 1178693  1
1975 Isom GE, Liu DHW, Way JL. Effect of sublethal doses of cyanide on glucose catabolism Biochemical Pharmacology. 24: 871-875. PMID 1125087 DOI: 10.1016/0006-2952(75)90157-4  1
1974 Isom GE, Way JL. Alteration of in vivo glucose metabolism by cobaltous chloride Toxicology and Applied Pharmacology. 27: 131-139. PMID 4850485 DOI: 10.1016/0041-008X(74)90180-X  1
1974 Isom GE, Way JL. Effect of oxygen on cyanide intoxication. VI. Reactivation of cyanide-inhibited glucose metabolism Journal of Pharmacology and Experimental Therapeutics. 189: 235-243. PMID 4823293  1
1974 Isom GE, Way JL. Cyanide intoxication: reactivation of cyanide inhibited cytochrome oxidase Federation Proceedings. 33.  1
1973 Isom G, Way JL. Cyanide intoxication: Protection with cobaltous chloride Toxicology and Applied Pharmacology. 24: 449-456. PMID 4704816 DOI: 10.1016/0041-008X(73)90051-3  1
1969 Isom GE, Nelson RB, Edlin AI. A comparison of the lethal and respiratory effects of morphine in Long-Evans and Sprague-Dawley rats. Archives Internationales De Pharmacodynamie Et De théRapie. 182: 130-8. PMID 5365228  1
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