| Year |
Citation |
Score |
| 2022 |
Merkler DJ, Hawley AJ, Eipper BA, Mains RE. Peptidylglycine a-amidating monooxygenase as a therapeutic target or biomarker. British Journal of Pharmacology. PMID 35124797 DOI: 10.1111/bph.15815 |
0.304 |
|
| 2020 |
O'Flynn BG, Prins KC, Shepherd BA, Forbrich VE, Suarez G, Merkler DJ. Identification of catalytically distinct arylalkylamine N-acetyltransferase splicoforms from Tribolium castaneum. Protein Expression and Purification. 105695. PMID 32681959 DOI: 10.1016/J.Pep.2020.105695 |
0.441 |
|
| 2020 |
O'Flynn BG, Lewandowski EM, Prins KC, Suarez G, McCaskey AN, Rios-Guzman NM, Anderson RL, Shepherd BA, Gelis I, Leahy JW, Chen Y, Merkler DJ. Characterization of Arylalkylamine -Acyltransferase from : An investigation into a potential next-generation insecticide target. Acs Chemical Biology. PMID 31967772 DOI: 10.1021/Acschembio.9B00973 |
0.415 |
|
| 2019 |
Anderson RL, Wallis DJ, Aguirre A, Holliday D, Merkler DJ. Knockdown of arylalkylamine N-acetyltransferase-like 2 in Drosophila melanogaster. Archives of Insect Biochemistry and Physiology. e21608. PMID 31385627 DOI: 10.1002/Arch.21608 |
0.353 |
|
| 2019 |
Battistini MR, O'Flynn BG, Shoji C, Suarez G, Galloway LC, Merkler DJ. Bm-iAANAT3: Expression and characterization of a novel arylalkylamine N-acyltransferase from Bombyx mori. Archives of Biochemistry and Biophysics. 661: 107-116. PMID 30452894 DOI: 10.1016/J.Abb.2018.11.015 |
0.454 |
|
| 2018 |
Anderson RL, Battistini MR, Wallis DJ, Shoji C, O'Flynn BG, Dillashaw JE, Merkler DJ. Bm-iAANAT and its potential role in fatty acid amide biosynthesis in Bombyx mori. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 135: 10-17. PMID 30103920 DOI: 10.1016/J.Plefa.2018.06.001 |
0.39 |
|
| 2018 |
O'Flynn BG, Suarez G, Hawley AJ, Merkler DJ. Insect Arylalkylamine -Acyltransferases: Mechanism and Role in Fatty Acid Amide Biosynthesis. Frontiers in Molecular Biosciences. 5: 66. PMID 30094237 DOI: 10.3389/Fmolb.2018.00066 |
0.396 |
|
| 2018 |
Handa S, Dempsey DR, Ramamoorthy D, Cook N, Guida WC, Spradling TJ, White JK, Woodcock HL, Merkler DJ. Mechanistic Studies of 1-Deoxy-D-Xylulose-5-Phosphate Synthase from. Biochemistry & Molecular Biology Journal. 4. PMID 29552677 DOI: 10.21767/2471-8084.100051 |
0.564 |
|
| 2017 |
Dempsey DR, Nichols DA, Battistini MR, Pemberton O, Ospina SR, Zhang X, Carpenter AM, O'Flynn BG, Leahy JW, Kanwar A, Lewandowski EM, Chen Y, Merkler DJ. Structural and Mechanistic Analysis of Drosophila melanogaster Agmatine N-Acetyltransferase, an Enzyme that Catalyzes the Formation of N-Acetylagmatine. Scientific Reports. 7: 13432. PMID 29044148 DOI: 10.1038/S41598-017-13669-6 |
0.405 |
|
| 2017 |
Aboalroub AA, Bachman AB, Zhang Z, Keramisanou D, Merkler DJ, Gelis I. Acetyl group coordinated progression through the catalytic cycle of an arylalkylamine N-acetyltransferase. Plos One. 12: e0177270. PMID 28486510 DOI: 10.1371/Journal.Pone.0177270 |
0.369 |
|
| 2016 |
White JK, Handa S, Vankayala SL, Merkler DJ, Woodcock HL. Thiamin Diphosphate Activation in 1-Deoxy-D-Xylulose 5-Phosphate Synthase: Insights into the Mechanism and Underlying Intermolecular Interactions. The Journal of Physical Chemistry. B. PMID 27537621 DOI: 10.1021/Acs.Jpcb.6B07248 |
0.595 |
|
| 2016 |
Jeffries KA, Dempsey DR, Farrell EK, Anderson RL, Garbade GJ, Gurina TS, Gruhonjic I, Gunderson CA, Merkler DJ. Glycine N-acyltransferase like 3 is responsible for long-chain N-acylglycine formation in N18TG2 cells. Journal of Lipid Research. PMID 27016726 DOI: 10.1194/Jlr.M062042 |
0.382 |
|
| 2016 |
Battistini MR, Shoji C, Handa S, Breydo L, Merkler DJ. Mechanistic binding insights for 1-deoxy-d-Xylulose-5-Phosphate synthase, the enzyme catalyzing the first reaction of isoprenoid biosynthesis in the malaria-causing protists, Plasmodium falciparum and Plasmodium vivax. Protein Expression and Purification. 120: 16-27. PMID 26699947 DOI: 10.1016/J.Pep.2015.12.003 |
0.618 |
|
| 2016 |
Battistini M, Mahajan S, Diaz D, Shaw L, Merkler D. A Facile, Microwave-Assisted Synthesis of an Adenosine-Ribose Probe for Binding-Based Profiling of Nucleoside and Nucleotide-Binding Proteins Current Microwave Chemistry. 3: 124-130. DOI: 10.2174/2213335602666150706182206 |
0.479 |
|
| 2015 |
Dempsey DR, Carpenter AM, Ospina SR, Merkler DJ. Probing the chemical mechanism and critical regulatory amino acid residues of Drosophila melanogaster arylalkylamine N-acyltransferase like 2. Insect Biochemistry and Molecular Biology. 66: 1-12. PMID 26476413 DOI: 10.1016/J.Ibmb.2015.10.003 |
0.461 |
|
| 2015 |
McIntyre NR, Lowe EW, Battistini MR, Leahy JW, Merkler DJ. Inactivation of peptidylglycine α-hydroxylating monooxygenase by cinnamic acid analogs. Journal of Enzyme Inhibition and Medicinal Chemistry. 1-12. PMID 26024288 DOI: 10.3109/14756366.2015.1046064 |
0.686 |
|
| 2015 |
Dempsey DR, Jeffries KA, Handa S, Carpenter AM, Rodriguez-Ospina S, Breydo L, Merkler DJ. Mechanistic and Structural Analysis of a Drosophila melanogaster Enzyme, Arylalkylamine N-Acetyltransferase Like 7, an Enzyme That Catalyzes the Formation of N-Acetylarylalkylamides and N-Acetylhistamine. Biochemistry. 54: 2644-58. PMID 25850002 DOI: 10.1021/Acs.Biochem.5B00113 |
0.646 |
|
| 2015 |
Mahajan S, Manetsch R, Merkler DJ, Stevens SM. Synthesis and evaluation of a novel adenosine-ribose probe for global-scale profiling of nucleoside and nucleotide-binding proteins. Plos One. 10: e0115644. PMID 25671571 DOI: 10.1371/Journal.Pone.0115644 |
0.542 |
|
| 2015 |
Mahajan S, Manetsch R, Merkler DJ, Stevens SM. Synthesis and evaluation of a novel adenosine-ribose probe for global-scale profiling of nucleoside and nucleotide-binding proteins Plos One. 10. DOI: 10.1371/journal.pone.0115644 |
0.48 |
|
| 2014 |
Dempsey DR, Jeffries KA, Bond JD, Carpenter AM, Rodriguez-Ospina S, Breydo L, Caswell KK, Merkler DJ. Mechanistic and structural analysis of Drosophila melanogaster arylalkylamine N-acetyltransferases. Biochemistry. 53: 7777-93. PMID 25406072 DOI: 10.1021/Bi5006078 |
0.433 |
|
| 2014 |
Jeffries KA, Dempsey DR, Behari AL, Anderson RL, Merkler DJ. Drosophila melanogaster as a model system to study long-chain fatty acid amide metabolism. Febs Letters. 588: 1596-602. PMID 24650760 DOI: 10.1016/J.Febslet.2014.02.051 |
0.326 |
|
| 2014 |
Dempsey DR, Bond JD, Carpenter AM, Rodriguez Ospina S, Merkler DJ. Expression, purification, and characterization of mouse glycine N-acyltransferase in Escherichia coli. Protein Expression and Purification. 97: 23-8. PMID 24576660 DOI: 10.1016/J.Pep.2014.02.007 |
0.456 |
|
| 2014 |
Dempsey DR, Jeffries KA, Anderson RL, Carpenter AM, Rodriquez Opsina S, Merkler DJ. Identification of an arylalkylamine N-acyltransferase from Drosophila melanogaster that catalyzes the formation of long-chain N-acylserotonins. Febs Letters. 588: 594-9. PMID 24444601 DOI: 10.1016/J.Febslet.2013.12.027 |
0.323 |
|
| 2013 |
Handa S, Ramamoorthy D, Spradling TJ, Guida WC, Adams JH, Bendinskas KG, Merkler DJ. Production of recombinant 1-deoxy-d-xylulose-5-phosphate synthase from Plasmodium vivax in Escherichia coli. Febs Open Bio. 3: 124-9. PMID 23772383 DOI: 10.1016/J.Fob.2013.01.007 |
0.575 |
|
| 2012 |
Handa S, Spradling TJ, Dempsey DR, Merkler DJ. Production of the catalytic core of human peptidylglycine α-hydroxylating monooxygenase (hPHMcc) in Escherichia coli. Protein Expression and Purification. 84: 9-13. PMID 22554821 DOI: 10.1016/J.Pep.2012.04.012 |
0.602 |
|
| 2012 |
An Z, Chen Y, Koomen JM, Merkler DJ. A mass spectrometry-based method to screen for α-amidated peptides. Proteomics. 12: 173-82. PMID 22106059 DOI: 10.1002/Pmic.201100327 |
0.534 |
|
| 2012 |
Farrell EK, Chen Y, Barazanji M, Jeffries KA, Cameroamortegui F, Merkler DJ. Primary fatty acid amide metabolism: conversion of fatty acids and an ethanolamine in N18TG2 and SCP cells. Journal of Lipid Research. 53: 247-56. PMID 22095832 DOI: 10.1194/Jlr.M018606 |
0.343 |
|
| 2011 |
Ivkovic M, Dempsey DR, Handa S, Hilton JH, Lowe EW, Merkler DJ. N-acylethanolamines as novel alcohol dehydrogenase 3 substrates. Archives of Biochemistry and Biophysics. 506: 157-64. PMID 21144815 DOI: 10.1016/J.Abb.2010.12.002 |
0.565 |
|
| 2010 |
McIntyre NR, Lowe EW, Belof JL, Ivkovic M, Shafer J, Space B, Merkler DJ. Evidence for substrate preorganization in the peptidylglycine α-amidating monooxygenase reaction describing the contribution of ground state structure to hydrogen tunneling. Journal of the American Chemical Society. 132: 16393-402. PMID 21043511 DOI: 10.1021/Ja1019194 |
0.691 |
|
| 2009 |
McIntyre NR, Lowe EW, Merkler DJ. Imino-oxy acetic acid dealkylation as evidence for an inner-sphere alcohol intermediate in the reaction catalyzed by peptidylglycine alpha-hydroxylating monooxygenase. Journal of the American Chemical Society. 131: 10308-19. PMID 19569683 DOI: 10.1021/Ja902716D |
0.644 |
|
| 2008 |
Merkler DJ, Asser AS, Baumgart LE, Carballo N, Carpenter SE, Chew GH, Cosner CC, Dusi J, Galloway LC, Lowe AB, Lowe EW, King L, Kendig RD, Kline PC, Malka R, et al. Substituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine alpha-hydroxylating monooxygenase (PHM). Bioorganic & Medicinal Chemistry. 16: 10061-74. PMID 18952446 DOI: 10.1016/J.Bmc.2008.10.013 |
0.656 |
|
| 2008 |
Farrell EK, Merkler DJ. Biosynthesis, degradation and pharmacological importance of the fatty acid amides. Drug Discovery Today. 13: 558-68. PMID 18598910 DOI: 10.1016/J.Drudis.2008.02.006 |
0.322 |
|
| 2006 |
Weiss ST, McIntyre NR, McLaughlin ML, Merkler DJ. The development of molecular clamps as drugs. Drug Discovery Today. 11: 819-24. PMID 16935750 DOI: 10.1016/J.Drudis.2006.07.011 |
0.654 |
|
| 2006 |
McIntyre NR, Lowe EW, Chew GH, Owen TC, Merkler DJ. Thiorphan, tiopronin, and related analogs as substrates and inhibitors of peptidylglycine alpha-amidating monooxygenase (PAM). Febs Letters. 580: 521-32. PMID 16405966 DOI: 10.1016/J.Febslet.2005.12.058 |
0.695 |
|
| 2005 |
Shonsey EM, Sfakianos M, Johnson M, He D, Falany CN, Falany J, Merkler DJ, Barnes S. Bile acid coenzyme A: amino acid N-acyltransferase in the amino acid conjugation of bile acids. Methods in Enzymology. 400: 374-94. PMID 16399361 DOI: 10.1016/S0076-6879(05)00022-4 |
0.37 |
|
| 2005 |
Chew GH, Galloway LC, McIntyre NR, Schroder LA, Richards KM, Miller SA, Wright DW, Merkler DJ. Ubiquitin and ubiquitin-derived peptides as substrates for peptidylglycine alpha-amidating monooxygenase. Febs Letters. 579: 4678-84. PMID 16098968 DOI: 10.1016/J.Febslet.2005.06.089 |
0.675 |
|
| 2004 |
Francisco WA, Wille G, Smith AJ, Merkler DJ, Klinman JP. Investigation of the pathway for inter-copper electron transfer in peptidylglycine α-amidating monooxygenase Journal of the American Chemical Society. 126: 13168-13169. PMID 15479039 DOI: 10.1021/Ja046888Z |
0.317 |
|
| 2004 |
Merkler DJ, Chew GH, Gee AJ, Merkler KA, Sorondo JP, Johnson ME. Oleic acid derived metabolites in mouse neuroblastoma N18TG2 cells. Biochemistry. 43: 12667-74. PMID 15449956 DOI: 10.1021/Bi049529P |
0.397 |
|
| 2004 |
Carpenter T, Poore DD, Gee AJ, Deshpande P, Merkler DJ, Johnson ME. Use of reversed phase HP liquid chromatography to assay conversion of N-acylglycines to primary fatty acid amides by peptidylglycine-alpha-amidating monooxygenase. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 809: 15-21. PMID 15282088 DOI: 10.1016/J.Jchromb.2004.05.028 |
0.354 |
|
| 2004 |
Owen TC, Merkler DJ. A new proposal for the mechanism of glycine hydroxylation as catalyzed by peptidylglycine alpha-hydroxylating monooxygenase (PHM). Medical Hypotheses. 62: 392-400. PMID 14975510 DOI: 10.1016/J.Mehy.2003.11.012 |
0.382 |
|
| 2003 |
Carpenter SE, Merkler DJ. An enzyme-coupled assay for glyoxylic acid. Analytical Biochemistry. 323: 242-6. PMID 14656531 DOI: 10.1016/J.Ab.2003.09.012 |
0.407 |
|
| 2003 |
Miller LA, Baumgart LE, Chew GH, deLong MA, Galloway LC, Jung KW, Merkler KA, Nagle AS, Poore DD, Yoon CH, Merkler DJ. Glutathione, S-substituted glutathiones, and leukotriene C4 as substrates for peptidylglycine alpha-amidating monooxygenase. Archives of Biochemistry and Biophysics. 412: 3-12. PMID 12646261 DOI: 10.1016/S0003-9861(02)00730-0 |
0.424 |
|
| 2000 |
DeBlassio JL, deLong MA, Glufke U, Kulathila R, Merkler KA, Vederas JC, Merkler DJ. Amidation of salicyluric acid and gentisuric acid: a possible role for peptidylglycine alpha-amidating monooxygenase in the metabolism of aspirin. Archives of Biochemistry and Biophysics. 383: 46-55. PMID 11097175 DOI: 10.1006/Abbi.2000.2047 |
0.418 |
|
| 2000 |
King L, Barnes S, Glufke U, Henz ME, Kirk M, Merkler KA, Vederas JC, Wilcox BJ, Merkler DJ. The enzymatic formation of novel bile acid primary amides. Archives of Biochemistry and Biophysics. 374: 107-17. PMID 10666288 DOI: 10.1006/Abbi.1999.1611 |
0.443 |
|
| 2000 |
Ritenour-Rodgers KJ, Driscoll WJ, Merkler KA, Merkler DJ, Mueller GP. Induction of peptidylglycine α-amidating monooxygenase in N18TG2 cells: A model for studying oleamide biosynthesis Biochemical and Biophysical Research Communications. 267: 521-526. PMID 10631094 DOI: 10.1006/Bbrc.1999.1977 |
0.425 |
|
| 1999 |
Merkler KA, Baumgart LE, DeBlassio JL, Glufke U, King L, Ritenour-Rodgers K, Vederas JC, Wilcox BJ, Merkler DJ. A pathway for the biosynthesis of fatty acid amides. Advances in Experimental Medicine and Biology. 469: 519-25. PMID 10667377 DOI: 10.1007/978-1-4615-4793-8_76 |
0.323 |
|
| 1999 |
Wilcox BJ, Ritenour-Rodgers KJ, Asser AS, Baumgart LE, Baumgart MA, Boger DL, DeBlassio JL, deLong MA, Glufke U, Henz ME, King L, Merkler KA, Patterson JE, Robleski JJ, Vederas JC, ... Merkler DJ, et al. N-acylglycine amidation: implications for the biosynthesis of fatty acid primary amides. Biochemistry. 38: 3235-45. PMID 10079066 DOI: 10.1021/Bi982255J |
0.38 |
|
| 1999 |
Merkler DJ, Glufke U, Ritenour-Rodgers KJ, Baumgart LE, DeBlassio JL, Merkler KA, Vederas JC. Formation of nicotinamide from nicotinuric acid by peptidylglycine α- amidating monooxygenase (PAM): A possible alternative route from nicotinic acid (niacin) to NADP in mammals [7] Journal of the American Chemical Society. 121: 4904-4905. DOI: 10.1021/Ja990517E |
0.319 |
|
| 1998 |
Francisco WA, Merkler DJ, Blackburn NJ, Klinman JP. Kinetic mechanism and intrinsic isotope effects for the peptidylglycine alpha-amidating enzyme reaction. Biochemistry. 37: 8244-52. PMID 9609721 DOI: 10.1021/Bi973004Y |
0.456 |
|
| 1997 |
Bell J, Ash DE, Snyder LM, Kulathila R, Blackburn NJ, Merkler DJ. Structural and functional investigations on the role of zinc in bifunctional rat peptidylglycine α-amidating enzyme Biochemistry. 36: 16239-16246. PMID 9405058 DOI: 10.1021/Bi970903D |
0.424 |
|
| 1997 |
Merkler DJ, Asser AS, Deblassio JL, Gee AJ, Johnson ME, Liang H, Merkler KA, Roy Chowdury S. N-acylglycines as substrates for peptidylglycine α-amidating enzyme Faseb Journal. 11. |
0.398 |
|
| 1996 |
Boswell JS, Reedy BJ, Kulathila R, Merkler D, Blackburn NJ. Structural investigations on the coordination environment of the active-site copper centers of recombinant bifunctional peptidylglycine alpha-amidating enzyme. Biochemistry. 35: 12241-50. PMID 8823157 DOI: 10.1021/Bi960742Y |
0.382 |
|
| 1996 |
Merkler DJ, Merkler KA, Stern W, Fleming FF. Fatty acid amide biosynthesis: A possible new role for peptidylglycine α-amidating enzyme and acyl-coenzyme A:Glycine N-acyltransferase Archives of Biochemistry and Biophysics. 330: 430-434. PMID 8660675 DOI: 10.1006/Abbi.1996.0272 |
0.485 |
|
| 1995 |
Merkler DJ, Kulathila R, Ash DE. The inactivation of bifunctional peptidylglycine α-amidating enzyme by benzylhydrazine: Evidence that the two enzyme-bound copper atoms are nonequivalent Archives of Biochemistry and Biophysics. 317: 93-102. PMID 7872809 DOI: 10.1006/abbi.1995.1140 |
0.356 |
|
| 1995 |
Merkler DJ, Kulathila R, Francisco WA, Ash DE, Bell J. The irreversible inactivation of two copper-dependent monooxygenases by sulfite: peptidylglycine α-amidating enzyme and dopamine β-monooxygenase Febs Letters. 366: 165-169. PMID 7540562 DOI: 10.1016/0014-5793(95)00516-C |
0.381 |
|
| 1994 |
Kulathila R, Consalvo AP, Fitzpatrick PF, Freeman JC, Snyder LM, Villafranca JJ, Merkler DJ. Bifunctional peptidylglcine alpha-amidating enzyme requires two copper atoms for maximum activity. Archives of Biochemistry and Biophysics. 311: 191-5. PMID 8185317 DOI: 10.1006/Abbi.1994.1225 |
0.43 |
|
| 1993 |
Merkler DJ, Schramm VL. Catalytic mechanism of yeast adenosine 5′-monophosphate deaminase. Zinc content, substrate specificity, pH studies, and solvent isotope effects Biochemistry. 32: 5792-5799. PMID 8504099 DOI: 10.1021/Bi00073A011 |
0.394 |
|
| 1993 |
Merkler DJ, Kline PC, Weiss P, Schramm VL. Transition-state analysis of AMP deaminase Biochemistry. 32: 12993-13001. PMID 8241153 DOI: 10.1021/Bi00211A007 |
0.338 |
|
| 1993 |
Freeman JC, Villafranca JJ, Merkler DJ. Redox cycling of enzyme-bound copper during peptide amidation Journal of the American Chemical Society. 115: 4923-4924. DOI: 10.1021/Ja00064A077 |
0.392 |
|
| 1992 |
Merkler DJ, Kulathila R, Tamburini PP, Young SD. Selective inactivation of the hydroxylase activity of bifunctional rat peptidylglycine α-amidating enzyme Archives of Biochemistry and Biophysics. 294: 594-602. PMID 1567215 DOI: 10.1016/0003-9861(92)90730-K |
0.392 |
|
| 1992 |
Consalvo AP, Young SD, Merkler DJ. Rapid fluorimetric assay for the detection of the peptidyl α-amdating enzyme intermediate using high-performance liquid chromatography Journal of Chromatography A. 607: 25-29. PMID 1447357 DOI: 10.1016/0021-9673(92)87050-I |
0.388 |
|
| 1992 |
Merkler DJ. 18O isotopic 13C NMR shift as proof that bifunctional peptidylglycine α-amidating enzyme is a monooxygenase Biochemistry. 31: 7282-7288. PMID 1387319 DOI: 10.1021/Bi00147A011 |
0.376 |
|
| 1992 |
Miller DA, Sayad KU, Kulathila R, Beaudry GA, Merkler DJ, Bertelsen AH. Characterization of a bifunctional peptidylglycine alpha-amidating enzyme expressed in Chinese hamster ovary cells. Archives of Biochemistry and Biophysics. 298: 380-8. PMID 1384431 DOI: 10.1016/0003-9861(92)90425-V |
0.384 |
|
| 1991 |
Merkler DJ, Young SD. Recombinant type A rat 75-kDa α-amidating enzyme catalyzes the conversion of glycine-extended peptides to peptide amides via an α-hydroxyglycine intermediate Archives of Biochemistry and Biophysics. 289: 192-196. PMID 1898062 DOI: 10.1016/0003-9861(91)90461-Q |
0.402 |
|
| 1989 |
Merkler DJ, Wali AS, Taylor J, Schramm VL. AMP Deaminase from yeast. Role in AMP degradation, large scale purification, and properties of the native and proteolyzed enzymes Journal of Biological Chemistry. 264: 21422-21430. PMID 2687280 |
0.33 |
|
| 1988 |
Merkler DJ, Srikumar K, Marchese-Ragona SP, Wedler FC. Aggregation and thermo-inactivation of glutamine synthetase from an extreme thermophile, Bacillus caldolyticus Biochimica Et Biophysica Acta (Bba)/Protein Structure and Molecular. 952: 101-114. PMID 2891380 DOI: 10.1016/0167-4838(88)90106-9 |
0.595 |
|
| 1987 |
Merkler DJ, Srikumar K, Wedler FC. Synergistic ligand protection and intermediates in the denaturation of extremely thermophilic glutamine synthetase Biochemistry. 26: 7805-7813. DOI: 10.1021/Bi00398A041 |
0.637 |
|
| 1985 |
Wedler FC, Merkler DJ. Thermostabilization of Bacillus caldolyticus glutamine synthetase by intrinsic and extrinsic factors Current Topics in Cellular Regulation. 26: 263-280. PMID 2866936 |
0.533 |
|
| 1981 |
Merkler DJ, Farrington GK, Wedler FC. Protein thermostability. Correlations between calculated macroscopic parameters and growth temperature for closely related thermophilic and mesophilic bacilli International Journal of Peptide and Protein Research. 18: 430-442. PMID 7341526 |
0.526 |
|
| 1981 |
Wedler FC, Shreve DS, Fisher KE, Merkler DJ. Complementarity of regulation for the two glutamine synthetases from Bacillus caldolyticus, an extreme thermophile. Archives of Biochemistry and Biophysics. 211: 276-87. PMID 6118092 DOI: 10.1016/0003-9861(81)90455-0 |
0.564 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 1990 |
Merkler DJ, Brenowitz M, Schramm VL. The rate constant describing slow-onset inhibition of yeast AMP deaminase by coformycin analogues is independent of inhibitor structure Biochemistry®. 29: 8358-8364. PMID 2252896 DOI: 10.1021/Bi00488A023 |
0.298 |
|
| 2019 |
Lan J, Liu J, Liao C, Merkler DJ, Han Q, Li J. A study for therapeutic treatment against Parkinson's Disease via Chou's 5-steps rule. Current Topics in Medicinal Chemistry. PMID 31629395 DOI: 10.2174/1568026619666191019111528 |
0.295 |
|
| 1993 |
Ray MVL, Van Duyne P, Bertelsen AH, Jackson-Matthews DE, Sturmer AM, Merkler DJ, Consalvo AP, Young SD, Gilligan JP, Shields PP. Production of recombinant salmon calcitonin by in vitro amidation of an escherichia coli produced precursor peptide Bio/Technology. 11: 64-70. PMID 7763486 DOI: 10.1038/nbt0193-64 |
0.295 |
|
| 1992 |
Bongers J, Felix AM, Campbell RM, Lee Y, Merkler DJ, Heimer EP. Semisynthesis of human growth hormone-releasing factors by alpha-amidating enzyme catalyzed oxidation of glycine-extended precursors. Peptide Research. 5: 183-9. PMID 1421807 |
0.293 |
|
| 1999 |
Kulathila R, Merkler KA, Merkler DJ. Enzymatic formation of C-terminal amides Natural Product Reports. 16: 145-154. PMID 10331284 DOI: 10.1039/A801346B |
0.291 |
|
| 1994 |
Merkler DJ. C-Terminal amidated peptides: Production by the in vitro enzymatic amidation of glycine-extended peptides and the importance of the amide to bioactivity Enzyme and Microbial Technology. 16: 450-456. PMID 7764886 DOI: 10.1016/0141-0229(94)90014-0 |
0.252 |
|
| 1990 |
Merkler DJ, Schramm VL. Catalytic and regulatory site composition of yeast AMP deaminase by comparative binding and rate studies: Resolution of the cooperative mechanism Journal of Biological Chemistry. 265: 4420-4426. PMID 2407736 |
0.23 |
|
| 1981 |
Karpel RL, Merkler DJ, Flowers BK, Delahunty MD. Involvement of basic amino acids in the activity of a nucleic acid helix-destabilizing protein. Biochimica Et Biophysica Acta. 654: 42-51. PMID 6268166 DOI: 10.1016/0005-2787(81)90134-9 |
0.213 |
|
| 1996 |
Schramm VL, Horenstein BA, Bagdassarian CK, Schwartz SD, Berti PJ, Rising KA, Scheuring J, Kline PC, Parkin DW, Merkler DJ. Enzymatic transition states and inhibitor design from principles of classical and quantum chemistry International Journal of Quantum Chemistry. 60: 1805-1813. DOI: 10.1002/(Sici)1097-461X(1996)60:8<1805::Aid-Qua8>3.0.Co;2-1 |
0.199 |
|
| 2019 |
Kim M, Snowden S, Suvitaival T, Ali A, Merkler DJ, Ahmad T, Westwood S, Baird A, Proitsi P, Nevado-Holgado A, Hye A, Bos I, Vos S, Vandenberghe R, Teunissen C, et al. Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31078433 DOI: 10.1016/J.Jalz.2019.03.004 |
0.196 |
|
| 2018 |
Merkler DJ, Leahy JW. Binding-based proteomic profiling and the fatty acid amides. Trends in Research. 1. PMID 30775690 DOI: 10.15761/TR.1000120 |
0.191 |
|
| 2022 |
Bhandari S, Bisht KS, Merkler DJ. The Biosynthesis and Metabolism of the -Acylated Aromatic Amino Acids: -Acylphenylalanine, -Acyltyrosine, -Acyltryptophan, and -Acylhistidine. Frontiers in Molecular Biosciences. 8: 801749. PMID 35047560 DOI: 10.3389/fmolb.2021.801749 |
0.177 |
|
| 2021 |
Ni R, Bhandari S, Mitchell PR, Suarez G, Patel NB, Lamb K, Bisht KS, Merkler DJ. Synthesis, Quantification, and Characterization of Fatty Acid Amides from In Vitro and In Vivo Sources. Molecules (Basel, Switzerland). 26. PMID 33925418 DOI: 10.3390/molecules26092543 |
0.164 |
|
| 2023 |
Li J, Merkler DJ, Han Q. Editorial: Aromatic amino acid metabolism-Volume II. Frontiers in Molecular Biosciences. 9: 1122151. PMID 36703916 DOI: 10.3389/fmolb.2022.1122151 |
0.161 |
|
| 2022 |
Zhang L, Tang Y, Merkler DJ, Han Q. Function, structure, evolution, regulation of a potent drug target, arylalkylamine N-acetyltransferase. Advances in Protein Chemistry and Structural Biology. 134: 211-223. PMID 36858736 DOI: 10.1016/bs.apcsb.2022.11.002 |
0.151 |
|
| 1993 |
Sollitti P, Merkler DJ, Estupiñán B, Schramm VL. Yeast AMP deaminase: Catalytic activity in Schizosaccharomyces pombe and chromosomal location in Saccharomyces cerevisiae Journal of Biological Chemistry. 268: 4549-4555. PMID 8440738 |
0.139 |
|
| 2018 |
O'Flynn BG, Hawley AJ, Merkler DJ. Insect Arylalkylamine-Acetyltransferases as Potential Targets for Novel Insecticide Design. Biochemistry & Molecular Biology Journal. 4. PMID 29552676 DOI: 10.21767/2471-8084.100053 |
0.138 |
|
| 2017 |
Anderson RL, Merkler DJ.
-FATTY ACYLGLYCINES: UNDERAPPRECIATED ENDOCANNABINOID-LIKE FATTY ACID AMIDES? Journal of Biology and Nature. 8: 156-165. PMID 29607420 |
0.136 |
|
| 2023 |
Chen J, Wu YC, Chen JK, Zhu XJ, Merkler D, Liao CH, Han Q. Elongases of Long-Chain Fatty Acids ELO2 and ELO9 Are Involved in Cuticle Formation and Function in Fecundity in the Yellow Fever Mosquito, . Insects. 14. PMID 36835758 DOI: 10.3390/insects14020189 |
0.135 |
|
| 2022 |
Tang Y, Chen H, Lin Z, Zhang L, Upadhyay A, Liao C, Merkler DJ, Han Q. Evolutionary genomics analysis reveals gene expansion and functional diversity of arylalkylamine N-acetyltransferases in Culicinae subfamily mosquitoes. Insect Science. PMID 35922881 DOI: 10.1111/1744-7917.13100 |
0.118 |
|
| 1987 |
Merkler DJ, Schramm VL. A preparative method for the enzymatic 5′-monophosphorylation of nucleosides Analytical Biochemistry. 167: 148-153. PMID 2829655 DOI: 10.1016/0003-2697(87)90145-X |
0.084 |
|
| 2013 |
Williams AJ, Buck BJ, Soukup DA, Merkler DJ. Geomorphic controls on biological soil crust distribution: A conceptual model from the Mojave Desert (USA) Geomorphology. 195: 99-109. DOI: 10.1016/J.Geomorph.2013.04.031 |
0.06 |
|
| 2006 |
Buck BJ, Wolff K, Merkler DJ, McMillan NJ. Salt mineralogy of Las Vegas Wash, Nevada: Morphology and subsurface evaporation Soil Science Society of America Journal. 70: 1639-1651. DOI: 10.2136/Sssaj2005.0276 |
0.042 |
|
| 2009 |
Drohan PJ, Merkler DJ. How do we find a true gypsophile? Geoderma. 150: 96-105. DOI: 10.1016/J.Geoderma.2009.01.008 |
0.033 |
|
| 2005 |
Drohan PJ, Merkler DJ, Buck BJ. Suitability of the plant root simulator probe for use in the Mojave Desert Soil Science Society of America Journal. 69: 1482-1491. DOI: 10.2136/Sssaj2004.0377 |
0.031 |
|
| 2012 |
Abella SR, Hurja JC, Merkler DJ, Denton CW, Brewer DG. Overstory-Understory Relationships along Forest Type and Environmental Gradients in the Spring Mountains of Southern Nevada, USA Folia Geobotanica. 47: 119-134. DOI: 10.1007/s12224-011-9108-7 |
0.026 |
|
| 2015 |
Baumann F, Buck BJ, Metcalf RV, McLaurin BT, Merkler DJ, Carbone M. The Presence of Asbestos in the Natural Environment is Likely Related to Mesothelioma in Young Individuals and Women from Southern Nevada. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 10: 731-7. PMID 25668121 DOI: 10.1097/Jto.0000000000000506 |
0.016 |
|
| 2012 |
Abella SR, Prengaman KA, Embrey TM, Schmid SM, Newton AC, Merkler DJ. A hierarchical analysis of vegetation on a Mojave Desert landscape, USA Journal of Arid Environments. 78: 135-143. DOI: 10.1016/j.jaridenv.2011.11.014 |
0.01 |
|
| Hide low-probability matches. |
