Jeffrey C. Culhane, Ph.D. - Publications

2008 Johns Hopkins University, Baltimore, MD 
Biochemistry, Organic Chemistry, Pharmaceutical Chemistry

11 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Kong L, Kadam RU, Giang E, Ruwona TB, Nieusma T, Culhane JC, Stanfield RL, Dawson PE, Wilson IA, Law M. Structure of hepatitis C virus envelope glycoprotein E1 antigenic site 314-324 in complex with antibody IGH526. Journal of Molecular Biology. PMID 26135247 DOI: 10.1016/j.jmb.2015.06.012  0.92
2012 Tarrant MK, Rho HS, Xie Z, Jiang YL, Gross C, Culhane JC, Yan G, Qian J, Ichikawa Y, Matsuoka T, Zachara N, Etzkorn FA, Hart GW, Jeong JS, Blackshaw S, et al. Regulation of CK2 by phosphorylation and O-GlcNAcylation revealed by semisynthesis. Nature Chemical Biology. 8: 262-9. PMID 22267120 DOI: 10.1038/nchembio.771  0.92
2011 Culhane JC, Fokin VV. Synthesis and reactivity of sulfamoyl azides and 1-sulfamoyl-1,2,3-triazoles. Organic Letters. 13: 4578-80. PMID 21812453 DOI: 10.1021/ol201705k  0.92
2010 Culhane JC, Wang D, Yen PM, Cole PA. Comparative analysis of small molecules and histone substrate analogues as LSD1 lysine demethylase inhibitors. Journal of the American Chemical Society. 132: 3164-76. PMID 20148560 DOI: 10.1021/ja909996p  0.92
2008 Ebner DC, Culhane JC, Winkelman TN, Haustein MD, Ditty JL, Ippoliti JT. Synthesis of novel oxazolidinone antimicrobial agents. Bioorganic & Medicinal Chemistry. 16: 2651-6. PMID 18077175 DOI: 10.1016/j.bmc.2007.11.040  0.92
2007 Szewczuk LM, Saldanha SA, Ganguly S, Bowers EM, Javoroncov M, Karanam B, Culhane JC, Holbert MA, Klein DC, Abagyan R, Cole PA. De novo discovery of serotonin N-acetyltransferase inhibitors. Journal of Medicinal Chemistry. 50: 5330-8. PMID 17924613 DOI: 10.1021/jm0706463  0.92
2007 Culhane JC, Cole PA. LSD1 and the chemistry of histone demethylation. Current Opinion in Chemical Biology. 11: 561-8. PMID 17851108 DOI: 10.1016/j.cbpa.2007.07.014  0.92
2007 Yang M, Culhane JC, Szewczuk LM, Jalili P, Ball HL, Machius M, Cole PA, Yu H. Structural basis for the inhibition of the LSD1 histone demethylase by the antidepressant trans-2-phenylcyclopropylamine. Biochemistry. 46: 8058-65. PMID 17569509 DOI: 10.1021/bi700664y  0.92
2007 Yang M, Culhane JC, Szewczuk LM, Gocke CB, Brautigam CA, Tomchick DR, Machius M, Cole PA, Yu H. Structural basis of histone demethylation by LSD1 revealed by suicide inactivation. Nature Structural & Molecular Biology. 14: 535-9. PMID 17529991 DOI: 10.1038/nsmb1255  0.92
2007 Szewczuk LM, Culhane JC, Yang M, Majumdar A, Yu H, Cole PA. Mechanistic analysis of a suicide inactivator of histone demethylase LSD1. Biochemistry. 46: 6892-902. PMID 17511474 DOI: 10.1021/bi700414b  0.92
2006 Culhane JC, Szewczuk LM, Liu X, Da G, Marmorstein R, Cole PA. A mechanism-based inactivator for histone demethylase LSD1. Journal of the American Chemical Society. 128: 4536-7. PMID 16594666 DOI: 10.1021/ja0602748  0.92
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