| Year |
Citation |
Score |
| 2024 |
Kalyanaraman H, Casteel DE, China SP, Zhuang S, Boss GR, Pilz RB. A plasma membrane-associated form of the androgen receptor enhances nuclear androgen signaling in osteoblasts and prostate cancer cells. Science Signaling. 17: eadi7861. PMID 38289986 DOI: 10.1126/scisignal.adi7861 |
0.609 |
|
| 2023 |
Kalyanaraman H, Casteel DE, Cabriales JA, Tat J, Zhuang S, Chan A, Dretchen KL, Boss GR, Pilz RB. The Antioxidant/Nitric Oxide-Quenching Agent Cobinamide Prevents Aortic Disease in a Mouse Model of Marfan Syndrome. Jacc. Basic to Translational Science. 9: 46-62. PMID 38362350 DOI: 10.1016/j.jacbts.2023.07.014 |
0.59 |
|
| 2023 |
Hu T, Kalyanaraman H, Pilz RB, Casteel DE. Phosphatase regulatory subunit MYPT2 knock-out partially compensates for the cardiac dysfunction in mice caused by lack of myosin light chain kinase 3. The Journal of Biological Chemistry. 104584. PMID 36889588 DOI: 10.1016/j.jbc.2023.104584 |
0.595 |
|
| 2022 |
Kalyanaraman H, Pal China S, Cabriales JA, Moininazeri J, Casteel DE, Garcia JJ, Wong VW, Chen A, Sah RL, Boss GR, Pilz RB. Protein Kinase G2 Is Essential for Skeletal Homeostasis and Adaptation to Mechanical Loading in Male but not Female Mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 36371651 DOI: 10.1002/jbmr.4746 |
0.585 |
|
| 2022 |
Chang S, Tat J, China SP, Kalyanaraman H, Zhuang S, Chan A, Lai C, Radic Z, Abdel-Rahman EA, Casteel DE, Pilz RB, Ali SS, Boss GR. Cobinamide is a strong and versatile antioxidant that overcomes oxidative stress in cells, flies, and diabetic mice. Pnas Nexus. 1: pgac191. PMID 36276587 DOI: 10.1093/pnasnexus/pgac191 |
0.567 |
|
| 2022 |
Sharma R, Kim JJ, Qin L, Henning P, Akimoto M, VanSchouwen B, Kaur G, Sankaran B, MacKenzie KR, Melacini G, Casteel DE, Herberg FW, Kim CW. An auto-inhibited state of protein kinase G and implications for selective activation. Elife. 11. PMID 35929723 DOI: 10.7554/eLife.79530 |
0.374 |
|
| 2022 |
Aminzai S, Hu T, Pilz RB, Casteel DE. PKGIα is activated by metal-dependent oxidation in vitro but not in intact cells. The Journal of Biological Chemistry. 298: 102175. PMID 35752367 DOI: 10.1016/j.jbc.2022.102175 |
0.641 |
|
| 2021 |
Schwaerzer GK, Casteel DE, Cividini F, Kalyanaraman H, Zhuang S, Gu Y, Dalton ND, Peterson KL, Dillmann WH, Boss GR, Pilz RB. Constitutive Protein Kinase G Activation Exacerbates Stress-induced Cardiomyopathy. British Journal of Pharmacology. PMID 34000062 DOI: 10.1111/bph.15530 |
0.597 |
|
| 2020 |
Wahwah N, Dhar D, Chen H, Zhuang S, Chan A, Casteel DE, Kalyanaraman H, Pilz RB, Boss GR. Metabolic interaction between amino acid deprivation and cisplatin synergistically reduces phosphoribosyl-pyrophosphate and augments cisplatin cytotoxicity. Scientific Reports. 10: 19907. PMID 33199755 DOI: 10.1038/s41598-020-76958-7 |
0.553 |
|
| 2020 |
Chan MH, Aminzai S, Hu T, Taran A, Li S, Kim C, Pilz RB, Casteel DE. A substitution in cGMP-dependent protein kinase 1 associated with aortic disease induces an active conformation in the absence of cGMP. The Journal of Biological Chemistry. PMID 32506052 DOI: 10.1074/Jbc.Ra119.010984 |
0.682 |
|
| 2019 |
Casteel DE. Letter by Casteel Regarding Article, "Blood Pressure-Lowering by the Antioxidant Resveratrol Is Counterintuitively Mediated by Oxidation of the cGMP-Dependent Protein Kinase". Circulation. 140: e808-e809. PMID 31765253 DOI: 10.1161/Circulationaha.119.042120 |
0.375 |
|
| 2019 |
Schwaerzer GK, Kalyanaraman H, Casteel DE, Dalton ND, Gu Y, Lee S, Zhuang S, Wahwah N, Schilling JM, Patel HH, Zhang Q, Makino A, Milewicz DM, Peterson KL, Boss GR, et al. Aortic pathology from protein kinase G activation is prevented by an antioxidant vitamin B analog. Nature Communications. 10: 3533. PMID 31387997 DOI: 10.1038/S41467-019-11389-1 |
0.637 |
|
| 2018 |
Ramdani G, Schall N, Kalyanaraman H, Wahwah N, Moheize S, Lee JJ, Sah RL, Pfeifer A, Casteel DE, Pilz RB. cGMP-dependent protein kinase-2 regulates bone mass and prevents diabetic bone loss. The Journal of Endocrinology. PMID 29914933 DOI: 10.1530/Joe-18-0286 |
0.635 |
|
| 2018 |
Qin L, Sankaran B, Aminzai S, Casteel D, Kim C. Structural basis for selective inhibition of human PKG Iα by the balanol-like compound N46. The Journal of Biological Chemistry. PMID 29769318 DOI: 10.1074/Jbc.Ra118.002427 |
0.329 |
|
| 2018 |
Haushalter KJ, Casteel DE, Raffeiner A, Stefan E, Patel HH, Taylor SS. Phosphorylation of Protein Kinase A (PKA) regulatory subunit RIα by Protein Kinase G (PKG) primes PKA for catalytic activity in cells. The Journal of Biological Chemistry. PMID 29378851 DOI: 10.1074/Jbc.M117.809988 |
0.505 |
|
| 2018 |
Kalyanaraman H, Schwaerzer G, Ramdani G, Castillo F, Scott BT, Dillmann W, Sah RL, Casteel DE, Pilz RB. Potein Kinase G Activation Reverses Oxidative Stress and Restores Osteoblast Function and Bone Formation in Male Mice With Type 1 Diabetes. Diabetes. PMID 29301852 DOI: 10.2337/Db17-0965 |
0.644 |
|
| 2017 |
Todd Milne G, Sandner P, Lincoln KA, Harrison PC, Chen H, Wang H, Clifford H, Qian HS, Wong D, Sarko C, Fryer R, Richman J, Reinhart GA, Boustany CM, Pullen SS, ... ... Casteel D, ... ... Casteel DE, et al. Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017. Bmc Pharmacology & Toxicology. 18: 64. PMID 29035170 DOI: 10.1186/s40360-017-0170-5 |
0.512 |
|
| 2017 |
Kalyanaraman H, Zhuang S, Pilz RB, Casteel DE. The Activity of cGMP-dependent Protein Kinase Iα is not Directly Regulated by Oxidation-induced Disulfide Formation at Cysteine 43. The Journal of Biological Chemistry. PMID 28360102 DOI: 10.1074/Jbc.C117.787358 |
0.698 |
|
| 2016 |
Sahu D, Gupta S, Hau AM, Nakashima K, Leivo MZ, Searles SC, Elson P, Bomalaski JS, Casteel DE, Boss GR, Hansel DE. Argininosuccinate Synthetase 1 Loss in Invasive Bladder Cancer Regulates Survival through General Control Nonderepressible 2 Kinase-Mediated Eukaryotic Initiation Factor 2α Activity and Is Targetable by Pegylated Arginine Deiminase. The American Journal of Pathology. PMID 27979310 DOI: 10.1016/J.Ajpath.2016.09.004 |
0.362 |
|
| 2016 |
Cho KJ, Casteel DE, Prakash P, Tan L, van der Hoeven D, Salim AA, Kim C, Capon RJ, Lacey E, Cunha SR, Gorfe AA, Hancock JF. AMPK and eNOS signaling regulates K-Ras plasma membrane interactions via cGMP-dependent Protein Kinase 2. Molecular and Cellular Biology. PMID 27697864 DOI: 10.1128/Mcb.00365-16 |
0.316 |
|
| 2016 |
Kalyanaraman H, Ramdani G, Joshua J, Schall N, Boss GR, Cory E, Sah RL, Casteel DE, Pilz RB. A Novel, Direct No Donor Regulates Osteoblast and Osteoclast Functions and Increases Bone Mass in Ovariectomized Mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 27391172 DOI: 10.1002/Jbmr.2909 |
0.618 |
|
| 2016 |
Kim JJ, Lorenz R, Arold ST, Reger AS, Sankaran B, Casteel DE, Herberg FW, Kim C. Crystal Structure of PKG I:cGMP Complex Reveals a cGMP-Mediated Dimeric Interface that Facilitates cGMP-Induced Activation. Structure (London, England : 1993). PMID 27066748 DOI: 10.1016/J.Str.2016.03.009 |
0.449 |
|
| 2016 |
Campbell JC, Kim JJ, Li KY, Huang GY, Reger AS, Matsuda S, Sankaran B, Link TM, Yuasa K, Ladbury JE, Casteel DE, Kim C. Structural Basis of Cyclic Nucleotide Selectivity in cGMP-Dependent Protein Kinase II. The Journal of Biological Chemistry. PMID 26769964 DOI: 10.1186/2050-6511-16-S1-A15 |
0.384 |
|
| 2016 |
Kim JJ, Lorenz R, Arold ST, Reger RS, Sankaran B, Casteel DE, Herberg FW, Kim C. Structural Analysis of the PKG I Regulatory Domain Reveals a Novel cGMP-Induced Dimeric Interface that Promotes Activation. Structure. DOI: 10.2210/Pdb4Z07/Pdb |
0.337 |
|
| 2015 |
Qin L, Reger AS, Guo E, Yang MP, Zwart P, Casteel DE, Kim C. Structures of cGMP-Dependent Protein Kinase (PKG) Iα Leucine Zippers Reveal an Interchain Disulfide Bond Important for Dimer Stability. Biochemistry. 54: 4419-22. PMID 26132214 DOI: 10.1021/Acs.Biochem.5B00572 |
0.408 |
|
| 2014 |
Reger AS, Yang MP, Koide-Yoshida S, Guo E, Mehta S, Yuasa K, Liu A, Casteel DE, Kim C. Crystal structure of the cGMP-dependent protein kinase II leucine zipper and Rab11b protein complex reveals molecular details of G-kinase-specific interactions. The Journal of Biological Chemistry. 289: 25393-403. PMID 25070890 DOI: 10.1074/Jbc.M114.575894 |
0.385 |
|
| 2014 |
Kalyanaraman H, Schwappacher R, Joshua J, Zhuang S, Scott BT, Klos M, Casteel DE, Frangos JA, Dillmann W, Boss GR, Pilz RB. Nongenomic thyroid hormone signaling occurs through a plasma membrane-localized receptor. Science Signaling. 7: ra48. PMID 24847117 DOI: 10.1126/Scisignal.2004911 |
0.668 |
|
| 2014 |
Huang GY, Kim JJ, Reger AS, Lorenz R, Moon EW, Zhao C, Casteel DE, Bertinetti D, Vanschouwen B, Selvaratnam R, Pflugrath JW, Sankaran B, Melacini G, Herberg FW, Kim C. Structural basis for cyclic-nucleotide selectivity and cGMP-selective activation of PKG i Structure. 22: 116-124. PMID 24239458 DOI: 10.1016/J.Str.2013.09.021 |
0.427 |
|
| 2013 |
Guo DC, Regalado E, Casteel DE, Santos-Cortez RL, Gong L, Kim JJ, Dyack S, Horne SG, Chang G, Jondeau G, Boileau C, Coselli JS, Li Z, Leal SM, Shendure J, et al. Recurrent gain-of-function mutation in PRKG1 causes thoracic aortic aneurysms and acute aortic dissections. American Journal of Human Genetics. 93: 398-404. PMID 23910461 DOI: 10.1016/J.Ajhg.2013.06.019 |
0.314 |
|
| 2013 |
Fridman A, Saha A, Chan A, Casteel DE, Pilz RB, Boss GR. Cell cycle regulation of purine synthesis by phosphoribosyl pyrophosphate and inorganic phosphate. The Biochemical Journal. 454: 91-9. PMID 23734909 DOI: 10.1042/Bj20130153 |
0.626 |
|
| 2013 |
Schwappacher R, Rangaswami H, Su-Yuo J, Hassad A, Spitler R, Casteel DE. cGMP-dependent protein kinase Iβ regulates breast cancer cell migration and invasion via interaction with the actin/myosin-associated protein caldesmon. Journal of Cell Science. 126: 1626-36. PMID 23418348 DOI: 10.1242/Jcs.118190 |
0.378 |
|
| 2013 |
Casteel DE, Schwappacher R, Rangaswami H, Su-Yuo J. cGMP-dependent protein kinase Iβ phosphorylates and regulates the function of the actin/myosin-associatedprotein caldesmon Bmc Pharmacology and Toxicology. 14. DOI: 10.1186/2050-6511-14-S1-P13 |
0.412 |
|
| 2013 |
Huang GY, Kim JJ, Reger AS, Lorenz R, Moon E, Zhao C, Casteel DE, Bertinetti D, VanSchouwen B, Selvaratnam R, Pflugrath JW, Sankaran B, Melacini G, Herberg FW, Kim C. Structures of human PKG reveal cGMP-selectived activation mechanisms Bmc Pharmacology and Toxicology. 14. DOI: 10.1186/2050-6511-14-S1-O16 |
0.469 |
|
| 2012 |
Casteel DE, Turner S, Schwappacher R, Rangaswami H, Su-Yuo J, Zhuang S, Boss GR, Pilz RB. Rho isoform-specific interaction with IQGAP1 promotes breast cancer cell proliferation and migration. The Journal of Biological Chemistry. 287: 38367-78. PMID 22992742 DOI: 10.1074/Jbc.M112.377499 |
0.642 |
|
| 2011 |
Kryshtafovych A, Moult J, Bartual SG, Bazan JF, Berman H, Casteel DE, Christodoulou E, Everett JK, Hausmann J, Heidebrecht T, Hills T, Hui R, Hunt JF, Seetharaman J, Joachimiak A, et al. Target highlights in CASP9: Experimental target structures for the critical assessment of techniques for protein structure prediction. Proteins. 79: 6-20. PMID 22020785 DOI: 10.1002/Prot.23196 |
0.339 |
|
| 2011 |
Osborne BW, Wu J, McFarland CJ, Nickl CK, Sankaran B, Casteel DE, Woods VL, Kornev AP, Taylor SS, Dostmann WR. Crystal structure of cGMP-dependent protein kinase reveals novel site of interchain communication. Structure (London, England : 1993). 19: 1317-27. PMID 21893290 DOI: 10.1016/J.Str.2011.06.012 |
0.392 |
|
| 2011 |
Lee JH, Li S, Liu T, Hsu S, Kim C, Woods VL, Casteel DE. The amino terminus of cGMP-dependent protein kinase Iβ increases the dynamics of the protein's cGMP-binding pockets. International Journal of Mass Spectrometry. 302: 44-52. PMID 21643460 DOI: 10.1016/J.Ijms.2010.07.021 |
0.371 |
|
| 2011 |
Kim JJ, Casteel DE, Huang G, Kwon TH, Ren RK, Zwart P, Headd JJ, Brown NG, Chow DC, Palzkill T, Kim C. Co-crystal structures of PKG Iβ (92-227) with cGMP and cAMP reveal the molecular details of cyclic-nucleotide binding. Plos One. 6: e18413. PMID 21526164 DOI: 10.1371/Journal.Pone.0018413 |
0.458 |
|
| 2011 |
Rangaswami H, Schwappacher R, Marathe N, Casteel DE, Haas B, Pfeifer A, Shattil S, Boss G, Pilz RB. Src activation by cGMP/PKG II in osteoblasts: characterization of a mechano-sensitive signalling complex Bmc Pharmacology. 11. DOI: 10.1186/1471-2210-11-S1-O24 |
0.711 |
|
| 2010 |
Rangaswami H, Schwappacher R, Marathe N, Zhuang S, Casteel DE, Haas B, Chen Y, Pfeifer A, Kato H, Shattil S, Boss GR, Pilz RB. Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts. Science Signaling. 3: ra91. PMID 21177494 DOI: 10.1126/Scisignal.2001423 |
0.758 |
|
| 2010 |
Casteel DE, Smith-Nguyen EV, Sankaran B, Roh SH, Pilz RB, Kim C. A crystal structure of the cyclic GMP-dependent protein kinase I{beta} dimerization/docking domain reveals molecular details of isoform-specific anchoring. The Journal of Biological Chemistry. 285: 32684-8. PMID 20826808 DOI: 10.1074/Jbc.C110.161430 |
0.672 |
|
| 2009 |
Casteel DE, Zhuang S, Zeng Y, Perrino FW, Boss GR, Goulian M, Pilz RB. A DNA polymerase-α·primase cofactor with homology to replication protein A-32 regulates DNA replication in mammalian cells Journal of Biological Chemistry. 284: 5807-5818. PMID 19119139 DOI: 10.1074/Jbc.M807593200 |
0.599 |
|
| 2009 |
Casteel DE, Smith-Nguyen EV, Sankaran B, Spraggon G, Hampton EN, Pilz RB, Taylor SS, Kim C. The first crystal structure of cyclic GMP-dependent protein kinase Iβ dimerization/docking domain reveals molecular details of isoform-specific anchoring Bmc Pharmacology. 9: P6. DOI: 10.1186/1471-2210-9-S1-P6 |
0.638 |
|
| 2008 |
Casteel DE, Zhang T, Zhuang S, Pilz RB. cGMP-dependent protein kinase anchoring by IRAG regulates its nuclear translocation and transcriptional activity. Cellular Signalling. 20: 1392-9. PMID 18450420 DOI: 10.1016/J.Cellsig.2008.03.009 |
0.696 |
|
| 2007 |
Zhang T, Zhuang S, Casteel DE, Looney DJ, Boss GR, Pilz RB. A cysteine-rich LIM-only protein mediates regulation of smooth muscle-specific gene expression by cGMP-dependent protein kinase. The Journal of Biological Chemistry. 282: 33367-80. PMID 17878170 DOI: 10.1074/Jbc.M707186200 |
0.661 |
|
| 2005 |
Casteel DE, Boss GR, Pilz RB. Identification of the interface between cGMP-dependent protein kinase Ibeta and its interaction partners TFII-I and IRAG reveals a common interaction motif. The Journal of Biological Chemistry. 280: 38211-8. PMID 16166082 DOI: 10.1074/Jbc.M507021200 |
0.635 |
|
| 2005 |
Kambo A, Sharma VS, Casteel DE, Woods VL, Pilz RB, Boss GR. Nitric oxide inhibits mammalian methylmalonyl-CoA mutase. The Journal of Biological Chemistry. 280: 10073-82. PMID 15647267 DOI: 10.1074/Jbc.M411842200 |
0.599 |
|
| 2003 |
Pilz RB, Casteel DE. Regulation of gene expression by cyclic GMP. Circulation Research. 93: 1034-46. PMID 14645134 DOI: 10.1161/01.Res.0000103311.52853.48 |
0.67 |
|
| 2003 |
Chen Y, Zhuang S, Cassenaer S, Casteel DE, Gudi T, Boss GR, Pilz RB. Synergism between calcium and cyclic GMP in cyclic AMP response element-dependent transcriptional regulation requires cooperation between CREB and C/EBP-beta. Molecular and Cellular Biology. 23: 4066-82. PMID 12773552 DOI: 10.1128/Mcb.23.12.4066-4082.2003 |
0.629 |
|
| 2002 |
Gudi T, Chen JC, Casteel DE, Seasholtz TM, Boss GR, Pilz RB. cGMP-dependent protein kinase inhibits serum-response element-dependent transcription by inhibiting rho activation and functions. The Journal of Biological Chemistry. 277: 37382-93. PMID 12119292 DOI: 10.1074/Jbc.M204491200 |
0.696 |
|
| 2002 |
Casteel DE, Zhuang S, Gudi T, Tang J, Vuica M, Desiderio S, Pilz RB. cGMP-dependent protein kinase Iβ physically and functionally interacts with the transcriptional regulator TFII-I Journal of Biological Chemistry. 277: 32003-32014. PMID 12082086 DOI: 10.1074/Jbc.M112332200 |
0.661 |
|
| 2000 |
Gudi T, Casteel DE, Vinson C, Boss GR, Pilz RB. NO activation of fos promoter elements requires nuclear translocation of G-kinase I and CREB phosphorylation but is independent of MAP kinase activation. Oncogene. 19: 6324-33. PMID 11175347 DOI: 10.1038/Sj.Onc.1204007 |
0.699 |
|
| 1999 |
Idriss SD, Gudi T, Casteel DE, Kharitonov VG, Pilz RB, Boss GR. Nitric oxide regulation of gene transcription via soluble guanylate cyclase and type I cGMP-dependent protein kinase. The Journal of Biological Chemistry. 274: 9489-93. PMID 10092632 DOI: 10.1074/Jbc.274.14.9489 |
0.682 |
|
| 1998 |
Casteel D, Suhasini M, Gudi T, Naima R, Pilz RB. Regulation of the erythroid transcription factor NF-E2 by cyclic adenosine monophosphate-dependent protein kinase Blood. 91: 3193-3201. PMID 9558374 DOI: 10.1182/Blood.V91.9.3193 |
0.676 |
|
| 1998 |
Casteel D, Suhasini M, Gudi T, Naima R, Pilz RB. Regulation of the Erythroid Transcription Factor NF-E2 by Cyclic Adenosine Monophosphate–Dependent Protein Kinase Blood. 91: 3193-3201. DOI: 10.1182/blood.v91.9.3193 |
0.348 |
|
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