Samuel F. Bakhoum, Ph.D. - Publications

Affiliations: 
2009 Biochemistry Dartmouth College, Hanover, NH, United States 
Area:
Cell Biology

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Loh PR, Genovese G, Handsaker RE, Finucane HK, Reshef YA, Palamara PF, Birmann BM, Talkowski ME, Bakhoum SF, McCarroll SA, Price AL. Insights into clonal haematopoiesis from 8,342 mosaic chromosomal alterations. Nature. PMID 29995854 DOI: 10.1038/s41586-018-0321-x  0.48
2018 Bakhoum SF, Ngo B, Laughney AM, Cavallo JA, Murphy CJ, Ly P, Shah P, Sriram RK, Watkins TBK, Taunk NK, Duran M, Pauli C, Shaw C, Chadalavada K, Rajasekhar VK, et al. Chromosomal instability drives metastasis through a cytosolic DNA response. Nature. PMID 29342134 DOI: 10.1038/nature25432  0.48
2017 Bakhoum SF, Kabeche L, Compton DA, Powell SN, Bastians H. Mitotic DNA Damage Response: At the Crossroads of Structural and Numerical Cancer Chromosome Instabilities. Trends in Cancer. 3: 225-234. PMID 28718433 DOI: 10.1016/j.trecan.2017.02.001  1
2015 Laughney AM, Elizalde S, Genovese G, Bakhoum SF. Dynamics of Tumor Heterogeneity Derived from Clonal Karyotypic Evolution. Cell Reports. 12: 809-20. PMID 26212324 DOI: 10.1016/j.celrep.2015.06.065  1
2015 Bakhoum SF, Kabeche L, Wood MD, Laucius CD, Qu D, Laughney AM, Reynolds GE, Louie RJ, Phillips J, Chan DA, Zaki BI, Murnane JP, Petritsch C, Compton DA. Numerical chromosomal instability mediates susceptibility to radiation treatment. Nature Communications. 6: 5990. PMID 25606712 DOI: 10.1038/ncomms6990  1
2014 Genovese G, Kähler AK, Handsaker RE, Lindberg J, Rose SA, Bakhoum SF, Chambert K, Mick E, Neale BM, Fromer M, Purcell SM, Svantesson O, Landén M, Höglund M, Lehmann S, et al. Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence. The New England Journal of Medicine. 371: 2477-87. PMID 25426838 DOI: 10.1056/NEJMoa1409405  1
2014 Bakhoum SF, Kabeche L, Murnane JP, Zaki BI, Compton DA. DNA-damage response during mitosis induces whole-chromosome missegregation. Cancer Discovery. 4: 1281-9. PMID 25107667 DOI: 10.1158/2159-8290.CD-14-0403  1
2014 Bakhoum SF, Swanton C. Chromosomal instability, aneuploidy, and cancer. Frontiers in Oncology. 4: 161. PMID 24995162 DOI: 10.3389/fonc.2014.00161  1
2014 Zaki BI, Suriawinata AA, Eastman AR, Garner KM, Bakhoum SF. Chromosomal instability portends superior response of rectal adenocarcinoma to chemoradiation therapy. Cancer. 120: 1733-42. PMID 24604319 DOI: 10.1002/cncr.28656  1
2014 Bakhoum SF, Silkworth WT, Nardi IK, Nicholson JM, Compton DA, Cimini D. The mitotic origin of chromosomal instability. Current Biology : Cb. 24: R148-9. PMID 24556433 DOI: 10.1016/j.cub.2014.01.019  1
2014 Bekelis K, Desai A, Bakhoum SF, Missios S. A predictive model of complications after spine surgery: the National Surgical Quality Improvement Program (NSQIP) 2005-2010. The Spine Journal : Official Journal of the North American Spine Society. 14: 1247-55. PMID 24211097 DOI: 10.1016/j.spinee.2013.08.009  1
2013 Bekelis K, Bakhoum SF, Desai A, Mackenzie TA, Roberts DW. Outcome prediction in intracranial tumor surgery: the National Surgical Quality Improvement Program 2005-2010. Journal of Neuro-Oncology. 113: 57-64. PMID 23436132 DOI: 10.1007/s11060-013-1089-3  1
2013 Bekelis K, Bakhoum SF, Desai A, Mackenzie TA, Goodney P, Labropoulos N. A risk factor-based predictive model of outcomes in carotid endarterectomy: the National Surgical Quality Improvement Program 2005-2010. Stroke; a Journal of Cerebral Circulation. 44: 1085-90. PMID 23412374 DOI: 10.1161/STROKEAHA.111.674358  1
2012 Bakhoum SF, Compton DA. Chromosomal instability and cancer: a complex relationship with therapeutic potential. The Journal of Clinical Investigation. 122: 1138-43. PMID 22466654 DOI: 10.1172/JCI59954  1
2012 Bakhoum SF, Compton DA. Kinetochores and disease: keeping microtubule dynamics in check! Current Opinion in Cell Biology. 24: 64-70. PMID 22196931 DOI: 10.1016/j.ceb.2011.11.012  1
2011 Bakhoum SF, Danilova OV, Kaur P, Levy NB, Compton DA. Chromosomal instability substantiates poor prognosis in patients with diffuse large B-cell lymphoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 7704-11. PMID 22184286 DOI: 10.1158/1078-0432.CCR-11-2049  1
2010 Manning AL, Bakhoum SF, Maffini S, Correia-Melo C, Maiato H, Compton DA. CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity. The Embo Journal. 29: 3531-43. PMID 20852589 DOI: 10.1038/emboj.2010.230  1
2010 Thompson SL, Bakhoum SF, Compton DA. Mechanisms of chromosomal instability. Current Biology : Cb. 20: R285-95. PMID 20334839 DOI: 10.1016/j.cub.2010.01.034  1
2009 Kollu S, Bakhoum SF, Compton DA. Interplay of microtubule dynamics and sliding during bipolar spindle formation in mammalian cells. Current Biology : Cb. 19: 2108-13. PMID 19931454 DOI: 10.1016/j.cub.2009.10.056  1
2009 Bakhoum SF, Genovese G, Compton DA. Deviant kinetochore microtubule dynamics underlie chromosomal instability. Current Biology : Cb. 19: 1937-42. PMID 19879145 DOI: 10.1016/j.cub.2009.09.055  1
2009 Bakhoum SF, Compton DA. Cancer: CINful centrosomes. Current Biology : Cb. 19: R642-5. PMID 19674544 DOI: 10.1016/j.cub.2009.06.039  1
2009 Bakhoum SF, Thompson SL, Manning AL, Compton DA. Genome stability is ensured by temporal control of kinetochore-microtubule dynamics. Nature Cell Biology. 11: 27-35. PMID 19060894 DOI: 10.1038/ncb1809  1
2007 Draper ND, Bakhoum SF, Haddrell AE, Agnes GR. Ion-induced nucleation in solution: promotion of solute nucleation in charged levitated droplets. Journal of the American Chemical Society. 129: 11364-77. PMID 17718487 DOI: 10.1021/ja067094i  1
2007 Manning AL, Ganem NJ, Bakhoum SF, Wagenbach M, Wordeman L, Compton DA. The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells. Molecular Biology of the Cell. 18: 2970-9. PMID 17538014 DOI: 10.1091/mbc.E07-02-0110  1
2006 Bakhoum SF. Bench-to-bedside solution to funding problems. Nature. 443: 506. PMID 17024068 DOI: 10.1038/443506b  1
2006 Stirling PC, Bakhoum SF, Feigl AB, Leroux MR. Convergent evolution of clamp-like binding sites in diverse chaperones. Nature Structural & Molecular Biology. 13: 865-70. PMID 17021621 DOI: 10.1038/nsmb1153  1
2005 Bakhoum SF, Bogan MJ, Agnes GR. Archiving and absolute quantitation of solutes separated by single charged droplet coulomb explosion. Analytical Chemistry. 77: 3461-5. PMID 15924376 DOI: 10.1021/ac048113e  1
2005 Bogan MJ, Bakhoum SF, Agnes GR. Promotion of alpha-cyano-4-hydroxycinnamic acid and peptide cocrystallization within levitated droplets with net charge. Journal of the American Society For Mass Spectrometry. 16: 254-62. PMID 15694775 DOI: 10.1016/j.jasms.2004.11.006  1
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