Benjamin Philmus, Ph.D. - Publications

2009 University of Hawai'i at Manoa, Honolulu, HI 
Organic Chemistry, Molecular Biology, Biochemistry

40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Rodrigues RR, Gurung M, Li Z, García-Jaramillo M, Greer R, Gaulke C, Bauchinger F, You H, Pederson JW, Vasquez-Perez S, White KD, Frink B, Philmus B, Jump DB, Trinchieri G, et al. Transkingdom interactions between Lactobacilli and hepatic mitochondria attenuate western diet-induced diabetes. Nature Communications. 12: 101. PMID 33397942 DOI: 10.1038/s41467-020-20313-x  0.01
2020 Fraser VN, Philmus B, Megraw M. Metabolomics analysis reveals both plant variety and choice of hormone treatment modulate vinca alkaloid production in . Plant Direct. 4: e00267. PMID 33005857 DOI: 10.1002/pld3.267  0.01
2020 Nofiani R, Weisberg AJ, Tsunoda T, Panjaitan RGP, Brilliantoro R, Chang JH, Philmus B, Mahmud T. Antibacterial Potential of Secondary Metabolites from Indonesian Marine Bacterial Symbionts. International Journal of Microbiology. 2020: 8898631. PMID 32676116 DOI: 10.1155/2020/8898631  1
2019 Videau P, Wells KN, Singh AJ, Eiting J, Proteau PJ, Philmus B. Expanding the Natural Products Heterologous Expression Repertoire in the Model Cyanobacterium Anabaena sp. Strain PCC 7120: Production of Pendolmycin and Teleocidin B-4. Acs Synthetic Biology. PMID 31846576 DOI: 10.1021/Acssynbio.9B00334  1
2019 Nofiani R, Philmus B, Nindita Y, Mahmud T. 3-Ketoacyl-ACP synthase (KAS) III homologues and their roles in natural product biosynthesis. Medchemcomm. 10: 1517-1530. PMID 31673313 DOI: 10.1039/C9Md00162J  0.01
2018 Swenson VA, Stacy AD, Gaylor MO, Ushijima B, Philmus B, Cozy LM, Videau NM, Videau P. Assessment and verification of commercially available pressure cookers for laboratory sterilization. Plos One. 13: e0208769. PMID 30533061 DOI: 10.1371/Journal.Pone.0208769  1
2018 Wells KN, Videau P, Nelson D, Eiting JE, Philmus B. The influence of sigma factors and ribosomal recognition elements on heterologous expression of cyanobacterial gene clusters in Escherichia coli. Fems Microbiology Letters. PMID 29982530 DOI: 10.1093/Femsle/Fny164  1
2018 Gallegos DA, Saurí J, Cohen RD, Wan X, Videau P, Vallota-Eastman AO, Shaala LA, Youssef DTA, Williamson RT, Martin GE, Philmus B, Sikora AE, Ishmael JE, McPhail KL. Jizanpeptins, Cyanobacterial Protease Inhibitors from a Symploca sp. Cyanobacterium Collected in the Red Sea. Journal of Natural Products. PMID 29808677 DOI: 10.1021/Acs.Jnatprod.8B00117  1
2018 Almabruk KH, Dinh LK, Philmus B. Self-resistance of natural product producers: Past, present and future focusing on self-resistant protein variants. Acs Chemical Biology. PMID 29763292 DOI: 10.1021/Acschembio.8B00173  0.01
2018 Videau P, Rivers OS, Tom SK, Oshiro RT, Ushijima B, Swenson VA, Philmus B, Gaylor MO, Cozy LM. The hetZ gene indirectly regulates heterocyst development at the level of pattern formation in Anabaena sp. strain PCC 7120. Molecular Microbiology. PMID 29676808 DOI: 10.1111/Mmi.13974  1
2018 Yan Q, Lopes LD, Shaffer BT, Kidarsa TA, Vining O, Philmus B, Song C, Stockwell VO, Raaijmakers JM, McPhail KL, Andreote FD, Chang JH, Loper JE. Secondary Metabolism and Interspecific Competition Affect Accumulation of Spontaneous Mutants in the GacS-GacA Regulatory System in Pseudomonas protegens. Mbio. 9. PMID 29339425 DOI: 10.1128/Mbio.01845-17  1
2017 Fenwick MK, Almabruk KH, Ealick SE, Begley TP, Philmus B. Biochemical characterization and structural basis of reactivity and regioselectivity differences of Burkholderia thailandensis and Burkholderia glumae 1,6-didesmethyltoxoflavin N-methyltransferase. Biochemistry. PMID 28665591 DOI: 10.1021/Acs.Biochem.7B00476  1
2017 Alanjary M, Kronmiller B, Adamek M, Blin K, Weber T, Huson D, Philmus B, Ziemert N. The Antibiotic Resistant Target Seeker (ARTS), an exploration engine for antibiotic cluster prioritization and novel drug target discovery. Nucleic Acids Research. PMID 28472505 DOI: 10.1093/Nar/Gkx360  0.01
2017 Yan Q, Philmus B, Chang JH, Loper JE. Novel mechanism of metabolic co-regulation coordinates the biosynthesis of secondary metabolites in Pseudomonas protegens. Elife. 6. PMID 28262092 DOI: 10.7554/Elife.22835  1
2017 Abugrain ME, Brumsted CJ, Osborn AR, Philmus B, Mahmud T. A Highly Promiscuous β-Ketoacyl-ACP Synthase (KAS) III-like Protein is Involved in Pactamycin Biosynthesis. Acs Chemical Biology. PMID 28060484 DOI: 10.1021/Acschembio.6B01043  0.01
2017 Yan Q, Philmus B, Chang JH, Loper JE. Author response: Novel mechanism of metabolic co-regulation coordinates the biosynthesis of secondary metabolites in Pseudomonas protegens Elife. DOI: 10.7554/Elife.22835.036  1
2016 Videau P, Wells KN, Gerwick WH, Philmus B. A workflow for the identification of biosynthetic gene clusters and heterologous production of cyanobacterial natural products. Planta Medica. 81: S1-S381. PMID 27976312 DOI: 10.1055/S-0036-1596128  1
2016 Philmus B. Review of Natural Products Desk Reference Natural Products Desk Reference . By John Buckingham, Caroline Cooper, and Rupert Purchase. CRC Press , Boca Raton, FL . 2016 . Hardcover, 235 pp. $103.95. ISBN-13: 978-1439873618 . Journal of Natural Products. 79: 2982. PMID 27933901 DOI: 10.1021/acs.jnatprod.6b00974  0.01
2016 Philmus B. Review of Natural Products Desk Reference Natural Products Desk Reference . By John Buckingham, Caroline Cooper, and Rupert Purchase. CRC Press , Boca Raton, FL . 2016 . Hardcover, 235 pp. $103.95. ISBN-13: 978-1439873618 . Journal of Natural Products. PMID 27805396 DOI: 10.1021/Acs.Jnatprod.6B00974  0.01
2016 Xu H, Chakrabarty Y, Philmus B, Mehta AP, Bhandari D, Hohmann HP, Begley TP. IIdentification of the first Riboflavin Catabolic Gene Cluster isolated from Microbacterium maritypicum G10. The Journal of Biological Chemistry. PMID 27590337 DOI: 10.1074/Jbc.M116.729871  1
2016 Videau P, Wells K, Singh AJ, Gerwick WH, Philmus B. Assessment of Anabaena sp. strain PCC 7120 as a heterologous expression host for cyanobacterial natural products: production of lyngbyatoxin A. Acs Synthetic Biology. PMID 27176641 DOI: 10.1021/Acssynbio.6B00038  1
2016 Yan Q, Philmus B, Hesse C, Kohen M, Chang JH, Loper JE. The Rare Codon AGA Is Involved in Regulation of Pyoluteorin Biosynthesis in Pseudomonas protegens Pf-5. Frontiers in Microbiology. 7: 497. PMID 27148187 DOI: 10.3389/Fmicb.2016.00497  1
2016 Fenwick MK, Philmus B, Begley TP, Ealick SE. Burkholderia glumae ToxA is a Dual Specificity Methyltransferase that Catalyzes the Last Two Steps of Toxoflavin Biosynthesis. Biochemistry. PMID 27070241 DOI: 10.1021/Acs.Biochem.6B00167  1
2016 Naurin S, Bennett J, Videau P, Philmus B, Soule T. The response regulator npun_f1278 is essential for scytonemin biosynthesis in the cyanobacterium Nostoc punctiforme ATCC29133. Journal of Phycology. PMID 27020740 DOI: 10.1111/Jpy.12414  1
2016 Videau P, Rivers OS, Ushijima B, Oshiro RT, Kim MJ, Philmus B, Cozy LM. Mutation of the murC and murB genes impairs heterocyst differentiation in Anabaena sp. strain PCC 7120. Journal of Bacteriology. PMID 26811320 DOI: 10.1128/Jb.01027-15  1
2015 Philmus B, Shaffer BT, Kidarsa TA, Yan Q, Raaijmakers JM, Begley TP, Loper JE. Investigations into the Biosynthesis, Regulation, and Self-Resistance of Toxoflavin in Pseudomonas protegens Pf-5. Chembiochem : a European Journal of Chemical Biology. PMID 26077901 DOI: 10.1002/Cbic.201500247  1
2015 Philmus B, Decamps L, Berteau O, Begley TP. Biosynthetic versatility and coordinated action of 5'-deoxyadenosyl radicals in deazaflavin biosynthesis. Journal of the American Chemical Society. 137: 5406-13. PMID 25781338 DOI: 10.1021/Ja513287K  1
2015 Mehta AP, Abdelwahed SH, Mahanta N, Fedoseyenko D, Philmus B, Cooper LE, Liu Y, Jhulki I, Ealick SE, Begley TP. Radical S-adenosylmethionine (SAM) enzymes in cofactor biosynthesis: a treasure trove of complex organic radical rearrangement reactions. The Journal of Biological Chemistry. 290: 3980-6. PMID 25477515 DOI: 10.1074/Jbc.R114.623793  1
2012 Decamps L, Philmus B, Benjdia A, White R, Begley TP, Berteau O. Biosynthesis of F0, precursor of the F420 cofactor, requires a unique two radical-SAM domain enzyme and tyrosine as substrate. Journal of the American Chemical Society. 134: 18173-6. PMID 23072415 DOI: 10.1021/Ja307762B  1
2012 Lai RY, Huang S, Fenwick MK, Hazra A, Zhang Y, Rajashankar K, Philmus B, Kinsland C, Sanders JM, Ealick SE, Begley TP. Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate. Journal of the American Chemical Society. 134: 9157-9. PMID 22568620 DOI: 10.1021/Ja302474A  1
2012 Greenwald JW, Greenwald CJ, Philmus BJ, Begley TP, Gross DC. RNA-seq analysis reveals that an ECF σ factor, AcsS, regulates achromobactin biosynthesis in Pseudomonas syringae pv. syringae B728a. Plos One. 7: e34804. PMID 22529937 DOI: 10.1371/Journal.Pone.0034804  1
2012 Philmus B, Abdelwahed S, Williams HJ, Fenwick MK, Ealick SE, Begley TP. Identification of the product of toxoflavin lyase: degradation via a Baeyer-Villiger oxidation. Journal of the American Chemical Society. 134: 5326-30. PMID 22304755 DOI: 10.1021/Ja211759N  1
2011 Christiansen G, Philmus B, Hemscheidt T, Kurmayer R. Genetic variation of adenylation domains of the anabaenopeptin synthesis operon and evolution of substrate promiscuity. Journal of Bacteriology. 193: 3822-31. PMID 21622740 DOI: 10.1128/Jb.00360-11  1
2011 Pribat A, Blaby IK, Lara-Núñez A, Jeanguenin L, Fouquet R, Frelin O, Gregory JF, Philmus B, Begley TP, de Crécy-Lagard V, Hanson AD. A 5-formyltetrahydrofolate cycloligase paralog from all domains of life: comparative genomic and experimental evidence for a cryptic role in thiamin metabolism. Functional & Integrative Genomics. 11: 467-78. PMID 21538139 DOI: 10.1007/S10142-011-0224-5  1
2011 Fenwick MK, Philmus B, Begley TP, Ealick SE. Toxoflavin lyase requires a novel 1-His-2-carboxylate facial triad. Biochemistry. 50: 1091-100. PMID 21166463 DOI: 10.1021/Bi101741V  1
2009 Philmus B, Guerrette JP, Hemscheidt TK. Substrate specificity and scope of MvdD, a GRASP-like ligase from the microviridin biosynthetic gene cluster. Acs Chemical Biology. 4: 429-34. PMID 19445532 DOI: 10.1021/Cb900088R  1
2009 Okumura HS, Philmus B, Portmann C, Hemscheidt TK. Homotyrosine-containing cyanopeptolins 880 and 960 and anabaenopeptins 908 and 915 from Planktothrix agardhii CYA 126/8. Journal of Natural Products. 72: 172-6. PMID 19115837 DOI: 10.1021/Np800557M  1
2008 Philmus B, Christiansen G, Yoshida WY, Hemscheidt TK. Post-translational modification in microviridin biosynthesis. Chembiochem : a European Journal of Chemical Biology. 9: 3066-73. PMID 19035375 DOI: 10.1002/Cbic.200800560  1
2008 Christiansen G, Molitor C, Philmus B, Kurmayer R. Nontoxic strains of cyanobacteria are the result of major gene deletion events induced by a transposable element. Molecular Biology and Evolution. 25: 1695-704. PMID 18502770 DOI: 10.1093/Molbev/Msn120  1
2003 Vízvárdi K, Kreutz C, Davis AS, Lee VP, Philmus BJ, Simo O, Michael K. Phototransamidation as a method for the synthesis of N-glycosyl asparagines Chemistry Letters. 32: 348-349.  1
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